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2. Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

6. Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer

8. Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)

10. Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

11. Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples

13. Supplementary Methods SM3 from A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer

14. Supplementary Table ST1 from A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer

15. Supplementary Figure S2 from A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer

16. Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11 /Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC).

18. A Systems Biology Approach to Investigate Kinase Signal Transduction Networks That Are Involved in Triple Negative Breast Cancer Resistance to Cisplatin

19. BCL-2 system analysis identifies high-risk colorectal cancer patients

20. Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression

22. Additional file 1 of Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer

25. AMPK‐regulated miRNA‐210‐3p is activated during ischaemic neuronal injury and modulates PI3K‐p70S6K signalling

26. Additional file 1 of Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples

27. Additional_File_1___Cell_line_authentication – Supplemental material for Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

30. List of Contributors

31. Abstract 6270: A radiosensitizer screen identifies a novel role for MDM2 inhibition in the radiosensitization of ER+ breast cancers in a p53 dependent manner

32. Systems analysis of protein signatures predicting cetuximab responses inKRAS,NRAS,BRAFandPIK3CAwild‐type patient‐derived xenograft models of metastatic colorectal cancer

35. Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

36. Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea

38. Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

39. Neratinib plus dasatinib is highly synergistic in HER2-positive breast cancer in vitroand in vivo

40. Supplementary_material – Supplemental material for Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer

41. Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre‐Clinical Detection of Off‐Target Toxicities Associated with Sunitinib Malate

43. Systems analysis of protein signatures predicting cetuximab responses in KRAS, NRAS, BRAF and PIK3CA wild‐type patient‐derived xenograft models of metastatic colorectal cancer.

44. Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)

47. Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer

49. A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib

50. A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer

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