585 results on '"Creek, Darren J"'
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2. Author Correction: The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate
3. Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii
4. Influence of chirality on protein corona formation of low-fouling chiral poly(2-oxazoline) coated nanoparticles
5. Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism
6. Prebiotic intervention with HAMSAB in untreated essential hypertensive patients assessed in a phase II randomized trial
7. Current and emerging target identification methods for novel antimalarials
8. Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia
9. Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
10. Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination
11. Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition
12. Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema
13. Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa
14. Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites
15. The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism
16. On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity
17. Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa
18. Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition
19. Discovery and development of 2-aminobenzimidazoles as potent antimalarials
20. Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity
21. Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4.
22. Multiplexed Native Mass Spectrometry Determination of Ligand Selectivity for Fatty Acid-Binding Proteins.
23. Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
24. Featured Cover
25. Microbial metabolism of l-tyrosine protects against allergic airway inflammation
26. Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells.
27. Ozonide Antimalarial Activity in the Context of Artemisinin-Resistant Malaria
28. Promising antimalarial hits from phenotypic screens: a review of recently-described multi-stage actives and their modes of action
29. On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity
30. Using the IDEOM Workflow for LCMS-Based Metabolomics Studies of Drug Mechanisms
31. Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics
32. Pharmacokinetic Predictors for Recurrent Malaria After Dihydroartemisinin-Piperaquine Treatment of Uncomplicated Malaria in Ugandan Infants
33. Maternal Diet and Gut Microbiota Influence Predisposition to Cardiovascular Disease in Offspring.
34. Multi-omics Based Identification of Specific Biochemical Changes Associated With PfKelch13-Mutant Artemisinin-Resistant Plasmodium falciparum
35. Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia
36. The Plasmodium falciparum artemisinin resistance-associated protein Kelch 13 is required for formation of normal cytostomes
37. Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites
38. Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy
39. Retargeting azithromycin analogues to have dual-modality antimalarial activity
40. Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii
41. Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution
42. The African killifish: A short‐lived vertebrate model to study the biology of sarcopenia and longevity.
43. Global Metabolic Analyses of Acinetobacter baumannii
44. Dietary fibre reverses adverse post-stroke outcomes in mice via short-chain fatty acids and its sensing receptors GPR41, GPR43 and GPR109A
45. The African killifish: A short‐lived vertebrate model to study the biology of sarcopenia and longevity
46. Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria
47. Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis
48. Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs
49. ThePlasmodium falciparumartemisinin resistance-associated protein Kelch 13 is required for formation of normal cytostomes
50. Novel Aroyl Guanidine Anti-Trypanosomal Compounds that Exert Opposing Effects on Parasite Energy Metabolism
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