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Your search keyword '"Cranz, Susanne"' showing total 5 results
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5 results on '"Cranz, Susanne"'

1. How does a DNA interacting enzyme change its specificity during molecular evolution? A site-directed mutagenesis study at the DNA binding site of the DNA-(adenine-N (super)6)-methyltransferase EcoRV

Author

Beck, Carsten, Cranz, Susanne, Solmaz, Merdol, Roth, Markus, and Jeltsch, Albert

Subjects
Biochemistry -- Research, DNA -- Research, Enzymes -- Physiological aspects, Molecules -- Analysis, Mutagenesis -- Analysis, Methyltransferases -- Analysis, Nitrogen -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the EcoRV DNA-(adenine-N (super)6)-methyltransferase. The use of the site-directed mutagenesis in investigating the function of the conserved and nonconserved residues within the loops flanking the DNA binding cleft of M.EcoRV is described.

Published
2001

2. Monomeric and dimeric bZIP transcription factor GCN4 bind at the same rate to their target DNA site

Author

Cranz, Susanne, Berger, Christine, Baici, Antonio, Jelesarov, Illian, and Bosshard, Hans Rudolf

Subjects
Leucine -- Chemical properties, Leucine -- Structure, DNA binding proteins -- Chemical properties, DNA binding proteins -- Structure, Biological sciences, Chemistry
Abstract

Basic leucine zipper (bZIP) transcription factors are dimeric proteins that recognize dyadic and mostly palindromic DNA sites. The kinetics of DNA recognition by unfolded monomeric and folded dimeric derivatives of GCN4 are reported using a 19 bp double-stranded DNA containing a palindromic CRE site.

Published
2004

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