2,532 results on '"Craik, David J."'
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2. Proximity Labelling Confirms the Involvement of Papain-Like Cysteine Proteases and Chaperones in Cyclotide Biosynthesis
3. Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides
4. Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation
5. Functional divergence in plant cyclotides and their role in plant defense
6. Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance
7. Topology in soft and biological matter
8. Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence
9. Gene-guided identifications of a structure-chimeric cyclotide viphi I from Viola philippica: Potential functions against cadmium and nematodes
10. Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor
11. Nucleation of a key beta-turn promotes cyclotide oxidative folding
12. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
13. Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom
14. Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis
15. Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1
16. Molecular dynamics simulations support a preference of cyclotide kalata B1 for phosphatidylethanolamine phospholipids
17. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
18. Cyclotides—Cyclic and Disulfide-Knotted Polypeptides
19. The Circular Bacteriocin enterocin NKR-5-3B has an Improved Stability Profile over Nisin
20. Isolation and Characterization of Insecticidal Cyclotides from Viola communis
21. Seasonal tissue-specific gene expression in wild crown-of-thorns starfish reveals reproductive and stress-related transcriptional systems
22. A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins
23. Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox
24. Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity
25. Sex-specific expression of pheromones and other signals in gravid starfish
26. Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation
27. Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
28. Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA
29. Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming
30. The prospect of substrate-based kinase inhibitors to improve target selectivity and overcome drug resistance.
31. Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides.
32. Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme
33. Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
34. Protocols for measuring the stability and cytotoxicity of cyclotides
35. Sortase‐Catalyzed Protein Domain Inversion
36. Delivery to, and Reactivation of, the p53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide
37. The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
38. Chemical synthesis of grafted cyclotides using a “plug and play” approach
39. Tertiary amide bond formation by an engineered asparaginyl ligase
40. The emerging landscape of peptide-based inhibitors of PCSK9
41. Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1
42. Converting peptides into drugs targeting intracellular protein–protein interactions
43. Scalable and Efficient In Planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics
44. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET
45. Make it or break it: Plant AEPs on stage in biotechnology
46. Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases
47. Design, Synthesis, and Structure–Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus‑2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
48. Modified horseshoe crab peptides target and kill bacteria inside host cells
49. Computational Design of α‐Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes
50. Deciphering the structure and mechanism‐of‐action of computer‐designed mastoparan peptides
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