1. Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma.
- Author
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Elbers PW, Craenen AJ, Driessen A, Stehouwer MC, Munsterman L, Prins M, van Iterson M, Bruins P, and Ince C
- Subjects
- Adult, Fatal Outcome, Humans, Hypothermia physiopathology, Male, Near Drowning physiopathology, Cardiopulmonary Resuscitation, Hypothermia therapy, Microcirculation, Microscopy, Polarization, Near Drowning therapy, Rewarming methods
- Abstract
The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR., (Copyright 2009 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2010
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