44 results on '"Cozza S."'
Search Results
2. Diabetes outcomes within integrated healthcare management programs
- Author
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Baldo, V., Lombardi, S., Cocchio, S., Rancan, S., Buja, A., Cozza, S., Marangon, C., Furlan, P., and Cristofoletti, M.
- Published
- 2015
- Full Text
- View/download PDF
3. N020 'What do you think about it?' The adolescentʼs voice affected by IBD
- Author
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Zaniboni, R, Cozza, S, and Lionetti, P
- Published
- 2018
- Full Text
- View/download PDF
4. Decarbonizing residential buildings with heat pumps: Transferability of front-runner experiences from Swiss Cantons
- Author
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Cozza, S., Chambers, J., Bolliger, R., Tarantino, Matteo, Patel, M. K., Tarantino M. (ORCID:0000-0002-4900-7815), Cozza, S., Chambers, J., Bolliger, R., Tarantino, Matteo, Patel, M. K., and Tarantino M. (ORCID:0000-0002-4900-7815)
- Abstract
The replacement of fossil-fuelled heating systems with systems using renewable energy sources is a central energy and climate policy concern and one of the prerequisites for reducing CO2 emissions to a climate-friendly level. The Swiss decarbonization strategy considers the use of electric air-to-water heat pumps (HP) operated with electricity generated from renewable sources or from a power mix with low CO2 content. However, the installation of HPs, which is essential for decarbonizing heat supply in buildings, is proceeding very slowly, and fossil fuel heating replacement is still the rule rather than the exception. This study investigates how a strong climate protection law (Energy Act of Basel-Stadt) has managed to overcome resistance to the installation of HPs, which is observed in many other Swiss cantons. The research question to be answered is whether the experience made with HP implementation in one location (with Basel-Stadt as forerunner canton) would be similarly viable in another location (Canton of Geneva). The results indicate that although the two cantons have different characteristics in terms of building stock, the potential of buildings where HP installation is considered 'easy' is high in both cases (50% in Basel-Stadt and 40% in Geneva). This is equivalent to 40% (in both cities) of the energy used for thermal use that is currently produced by fossil energy and that could be instead generated with HPs. Although there are many factors to take into account in order to design effective policies that are truly effective for the extensive installation of HP, it is worth remembering that there are many cases where it is already possible to easily install a HP today, and these should be the starting point.(c) 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Published
- 2022
5. Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes 11 Medical and Health Sciences 1103 Clinical Sciences
- Author
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Mirijello, A, Viazzi, F, Fioretto, P, Giorda, C, Ceriello, A, Russo, G, Guida, P, Pontremoli, R, De Cosmo, S, Cimino, A, Fava, D, Meloncelli, I, Nicolucci, A, Pellegrini, F, Rossi, M, Turco, S, Vespasiani, G, Graziano, G, Lucisano, G, Memmo, R, Pellicciotta, E, Paciotti, V, Pupillo, M, Armentano, G, Giovannini, C, Armentano, V, Laudato, M, Acquati, S, Ciardullo, A, Laffi, G, Felace, G, Taboga, C, Tortul, C, Santantonio, G, Suraci, C, Ghisoni, G, Raffa, M, Genovese, S, Lovagnini-Scher, C, Rampini, P, Rocca, A, Ruggeri, P, Tortato, E, Cotti, L, Cristofaro, M, Tagliaferri, M, Comoglio, M, Fornengo, R, Gentile, F, Gigante, A, Mastinu, F, Di Benedetto, A, Pata, P, Arcangeli, A, Orsini, P, Acler, P, De Blasi, G, Cicioni, G, Pocciati, S, Marangoni, A, Nogara, A, Lanero, M, Bertero, M, Damassino, R, Bergonzini, C, Schumtz, L, Seksich, L, Pipitone, A, Boaretto, M, Manfroi, I, Parmesan, L, Conte, B, Soccol, F, Pagano, A, Papini, E, Rinaldi, R, Petrucci, L, Graziano, F, Chianelli, M, Silvagni, S, Rosco, M, Ansaldi, E, Malvicino, F, Battezzati, M, Maresca, P, Palenzona, C, Boemi, M, Rabini, R, Brandoni, G, Lanari, L, Gatti, C, Testa, I, Cherubini, V, Doveri, G, Pecorelli, L, Ciccarelli, A, Gallardini, M, Courthoud, R, Sara Bredy, S, Ricciardi, G, Vitalone, G, Setti, D, Contrini, P, Corsi, A, Ghigliotti, V, Oddone, G, Ponzani, P, Valbonesi, G, Mazzini, V, Di Berardino, P, Colleluori, P, Montani, V, Trosini, V, Velussi, M, Alfidi, P, Verdecchia, B, Baliva, L, Di Pietro, A, Franchi, G, Luce, R, Pianta, A, Ferrari, M, Balzano, S, Beltranello, G, Dal Fabbro, S, Arico, C, Cervo, L, Zanon, R, Rossa, S, Di Pace, M, Ciavarella, A, Giangiulio, S, Grimaldi, M, Mustacchio, A, Fattor, B, Monauni, T, Cristini, M, Orion, G, Crazzolara, D, Amor, F, Eisath, J, Lintner, S, Garavelli, S, Calari, T, Marini, P, Sandri, O, Scala, M, Stroppa, C, Trentin, A, Carlin, R, Carli, B, Sandona, M, Zortea, C, Bonet, L, Pradel, L, Reato, S, Buschini, M, Bonfiglioli, D, Mones, D, Beldi, F, Morea, A, Bondesan, L, Perbellini, S, Valentini, U, Agosti, B, Corsini, R, Girelli, A, Zarra, E, Rocca, L, Bergmann, M, Pradi, I, Unterkircher, S, Piok, M, Pichler, M, Trinchera, A, Palama, G, Palma, P, Carboni, L, Murtas, M, Mudadu, T, Turco, M, Floris, M, Delogu, A, Farris, L, Songini, M, Piras, G, Seguro, R, Floris, R, Corona, G, Lai, M, Piras, E, Contini, P, Cocco, S, Pilosu, R, Sannia, M, Spanu, F, Busciantella Ricci, N, Cartechini, M, Agostinelli, G, Fiorelli, C, Nuzzi, A, Ballauri, C, Lesina, A, Romeo, F, Giudici, G, Maciejewska, E, Deroma, A, Paduano, M, Rossi, L, Vagnini, C, Dolci, M, Mori, M, Baccetti, F, Gregori, G, Straface, E, Pozzuoli, G, Barone, M, Stasio, G, Tondini, S, Borgoni, F, Grosso, J, Scarsellato, C, Sciulli, A, De Marco, F, Confortin, L, Marin, N, Lamonica, M, Gialdino, S, Borzi, V, Gatta, C, Rapisard, R, Strano, S, Calabro, M, Puccio, L, Zolli, M, Coracina, A, Starnone, V, Del Buono, A, Terracciano, A, Monda, M, Castro, F, Guaglianone, A, Maccari, V, Corsi, L, Versari, G, Falivene, M, Boletto, N, Corsi, S, Marafetti, L, Vitacolonna, E, Capani, F, Caputo, L, Di Nisio, L, Simonetti, F, Boscolo Bariga, A, Ballarin, G, De Boni, S, Di Benedetto, S, Chiambretti, A, Di Vito, L, Pascuzzo, M, Urli, P, Rumi, P, Balzarini, B, Galli, P, Castellan, M, Giannetti, A, Russotti, C, De Blasi, A, Perna, A, Campanelli, C, Ranchelli, A, Biccheri, D, Dadi, G, Massa, L, Baldi, G, Sciacca, F, Costanzo, E, Spada, M, Paolini, G, Ziller, P, Portolan, F, Pasolini, G, Ghilardi, G, Fiorina, P, Grata, M, Capretti, L, Speroni, G, Fugazza, L, Massafra, C, Lovagnini Scher, A, Cimicchi, M, Percudani, C, Risolo, T, Sacco, P, Gidoni Guarnieri, G, Piccolo, D, Bravin, C, De Noni, E, Scarpel, M, Marcon, M, Giacon, F, Panebianco, G, Tadiotto, F, Da Tos, V, D'Ambrosio, M, Pellizzola, D, Zampini, M, Frezzati, E, Mari, E, Raminelli, E, Gaiti, D, Bosi, E, Chierici, G, Pilla, S, Copelli, M, Zanichelli, P, Bertelli, L, Caretta, P, Vezzani, V, Bodecchi, S, Longobucco, A, Di Lembo, S, Spotti, E, Carrai, E, Degli Innocenti, A, Manini, L, Persico, R, Rossi, C, Magro, G, Marelli, G, Vilei, V, Andrioli, M, Bellato, L, Fedeli, M, Merlini, A, Pinelli, G, Marin, G, Contin, M, Gallo, A, Parlato, P, Pecchielan, W, Jacovacci, J, Placentino, G, Richini, D, Molinari, S, Strazzeri, R, Fabbri, T, Di Bartolo, P, Garrapa, G, D'Incau, F, Lagomanzini, P, Conte, P, Todesco, F, Foglini, P, Pantanetti, P, Bedetta, C, Maricotti, R, Tomasi, F, Monesi, M, Graziani, R, Beretta, F, Penna, L, Guberti, A, Dazzi, D, Forte, E, Gasbarrone, A, Marrocco, T, Moschetta, R, Tuccinardi, F, De Meo, F, Coppola, A, Pirolozzi, P, Placitelli, E, Vallefuoco, R, Catone, B, Ceschia, S, Urban, M, Fabbri, F, Torresani, M, Crovetto, R, Battistini, M, Carosia, P, Viviani, G, Durante, A, Pais, F, Lilliu, V, Quieto, C, D'Ugo, E, Squadrone, M, Amenduni, T, Iovannisci, M, Della Penna, L, Potente, F, Delle Donne, T, Massa, C, Ulisse, M, De Berardinis, S, Guarnieri, I, Pace, S, Splendiani, M, Di Giuseppe, R, Brunato, B, Assaloni, R, Muraro, R, Loro, R, Bucciol, S, Lavacca, C, Sabbatini, G, Quadri, F, Sambuco, L, Santacroce, C, Paola Caretta, D, Marino, C, Micheletti, A, Petrelli, A, Corda, A, Pisano, L, Guaita, G, Deias, C, Trevisan, G, Coletti, I, Iannarelli, R, De Luca, A, Minnucci, A, Antenucci, D, Di Florio, C, Angelicola, G, Bosco, A, Fresco, R, Di Marco, G, Ugolotti, D, Cadossi, T, Di Caro, P, Mazzocchetti, M, Buzzetti, R, Leto, G, Gnessi, C, Cipolloni, L, Foffi, C, Moretti, C, Venditti, C, Meniconi, R, Bertoli, S, Cosimi, S, Di Cianni, G, Turco, A, Richini, A, Marconi, S, Sannino, C, Lemmi, P, Giuntoli, S, Manfre, N, Giannini, F, Di Carlo, A, Casadidio, I, Melandri, P, Maolo, G, Polenta, B, Piccinini, N, Vincenti, C, Pastore, N, Mega, P, Magurano, E, Cananiello, A, Francescutto, C, Brussa Toi, E, Gaspardo, G, Angeli, L, Ronchese, L, Sciangula, L, Ciucci, A, Contartese, A, Banfi, E, Castelli, E, Tatti, P, Bloise, D, Di Mauro, P, Masselli, L, Lo Presti, A, Scarpitta, A, Gambina, F, Venezia, A, Morea, R, Lagonigro, G, Copeta, G, Iannucci, V, Milano, V, Trupo, M, Lochmann, A, Marchetto, P, Incelli, G, De Paola, G, Steiger, M, Gamper, M, Breitenberger, S, Holzner, M, Frischmann, J, Lambiase, C, Di Vece, T, D'Aniello, M, Fezza, M, Giordano, C, Leo, F, Saitta, G, Cucinotta, D, Di Vieste, G, Pintaudi, B, Mancuso, T, Musacchio, N, Giancaterini, A, Pessina, L, Salis, G, Schivalocchi, F, Testori, G, Cerutti, N, Morpugo, P, Cavaletto, M, Bonino, G, Morreale, F, Mariani, G, Ragonesi, P, Bollati, P, Colapinto, P, Falqui, L, Bortolato, L, Cosma, A, Pistolato, P, Centenaro, B, Ceccato, A, Campobasso, G, Zaurino, F, Mazzotta, G, Manti, R, Da Ros, R, Carlucci, S, Narduzzi, L, Bortolotto, D, D'Acunto, L, Stanic, L, Volpi, A, Cospite, A, Manicardi, V, Michelini, M, Finardi, L, Borghi, F, Manicardi, E, Lombardi, S, Tommasi, C, Iaccarino, M, Cozza, S, Binotto, M, Marini, F, Mecenero, I, Massignani, S, Stecco, P, Urbani, E, Massariol, W, Parolin, R, Gatti, A, Bonavita, M, Creso, E, Giannettino, R, Gobbo, M, Iovine, C, Riccardi, G, Iazzetta, N, Giannattasio, C, Egione, O, Galdieri, S, Velotti, A, Azzolina, A, Annicelli, G, Sorrentino, T, Gaeta, I, Zenari, L, Bertolini, L, Sorgato, C, Grippaldi, F, Stroppiana, M, Popolizio, R, Carbone, N, Grasso, S, Abate, S, Gaggero, G, Strazzabosco, M, Brun, E, Carlesi, G, Garrone, S, Cicalo, A, Clausi, C, Cau, R, Manconi, A, Carboni, A, Angius, M, Pinna, A, Caria, S, Filigheddu, G, Tonolo, G, Carta, I, Calebich, S, Burlotti, C, Saglietti, G, Schellino, A, Madau, G, Cossu, M, Mulas, F, Zoccheddu, S, Balsanelli, M, Fetonti, M, Rotolo, A, Sambo, P, Secchi, E, Angotzi, M, Loddoni, S, Brundu, I, Careddu, F, Becciu, A, Gabriella Piras, G, Novara, F, Cipro, F, Torchio, G, Palumbo, P, Bianchi, A, Colucci, G, La Motta, G, Tiengo, A, Avogaro, A, Bruttomesso, D, Crepaldi, C, Fadini, G, Guarnieri, G, Lavagnini, M, Maran, A, Vedovato, M, De Kreutzenberg, V, Fedele, D, Lapolla, A, Sartore, G, Bax, G, Cardone, C, Dalfra, M, Masin, M, Toniato, R, Piarulli, F, Mattina, G, Fulantelli, M, Gioia, D, Conti, M, Ridola, G, D'Agati, F, Grossi, G, Zavaroni, I, Dei Cas, A, Franzini, L, Usberti, E, Antonimi, M, Anelli, N, Poli, R, Ridolfi, V, Michela, M, Haddoub, S, Prampolini, G, Muoio, A, Filippi, D, Bucci, F, Tardio, S, Calderini, M, Magotti, M, Quarantelli, C, Vernazza, M, Carolfi, A, Saracca, R, Picchio, E, Del Sindaco, P, Spalluto, A, Maggiulli, L, Torreggiani, V, Rastelletti, S, Ugolini, C, Pucci, N, Magi, S, Muratori, S, La Penna, G, Consoli, A, Galeone, F, Magiar, A, Gherardini, V, Moretti, L, Bientinesi, M, Landi, L, Bernardi, A, Del Prato, S, Miccoli, R, Bianchi, C, Penno, G, Venditti, F, Anichini, R, De Bellis, A, Bruschi, T, Butelli, L, Gioffredi, M, Gori, R, Picciafuochi, R, Malagoli, R, Bernini, A, Gelisio, R, Zanon, M, Del Bianco, A, Bamiston, A, Signorato, M, Citro, G, Calabrese, M, Ianni, L, Lorenzetti, M, Marsocci, A, Guizzotti, S, Memoli, G, Cabasino, F, Farci, F, Atzori, A, Sanna, A, Ghiani, M, Siotto, I, Sedda, M, Manis, A, Loddo, C, Loddo, I, Seguro, P, Cuomo, A, Orlando, L, Olanda, G, Pucci, A, Massenzo, M, Sardu, C, Perrone, G, Corazziere, F, La Puzza, I, Tripodi, P, Riggio, S, Giampaolo, A, Mannino, D, Aleandri, A, Guidi, M, Battisti, B, Faraglia, M, Lilli, V, Leotta, S, Visalli, N, Gagliardi, A, Fontana, L, Altomare, M, Carletti, S, Abbruzzese, S, Chiaramonte, F, Giordano, R, Rossini, M, Migneco, G, Cappelloni, D, Urbani, A, Piergiovanni, F, Simonetta, A, Massimiani, F, Bulzomi, R, Giuliano, M, Pennafina, M, Di Perna, P, D'Accinni, M, Paolucci, D, D'Ubaldi, A, D'Angelo, M, Masaro, G, Pietrantoni, M, Fratini, M, La Rosa, R, Poggi, M, Piccirilli, F, Pisano, R, Saponara, C, Conforti, I, Penza, A, Scalpone, R, Lo Pinto, S, Iacovella, L, Caccamo, C, Sposito, S, Teodonio, C, Restuccia, M, Mirto, G, Girardello, R, Gennaro, R, De Moliner, L, Bettini, E, Mattuzzi, A, Speese, K, Frisinghelli, F, Locatelli, F, Nicoletti, M, Trojan, N, Centis, R, L Volsi, P, Levis, E, Zanette, G, Comba, G, Ballatore, L, Cattaneo, A, Aglialoro, A, Guido, R, Patrone, M, Zecchini, M, Clementi, L, Galetta, M, Marconi, V, Bordin, P, Perale, L, Vinci, C, Sira Zanon, M, Geretto, L, Toffolo, C, Furlan, M, Mazzanti, G, Vinci, M, Sica, V, Armeni, M, Derai, R, Ennas, O, Mamusa, S, Pisano, M, Carreras, L, Rauseo, A, Cervone, S, Leggieri, A, Pontonio, M, Sturaro, R, Quattrocchi, F, Molinaro, M, Trasatti, M, Ferretti, B, Labarile, G, Baule, G, Gentilini, A, Spanu, M, Fancellu, A, Bianco, P, Lione, L, Massazza, G, Bocchio, G, Bosco, E, Monachesi, M, Carta, G, Boschetti, M, Ceresola, E, Venier, E, Calcaterra, F, Cataldi, F, Miola, M, Manfrini, S, Lai, A, Locci, B, Putzu, D, Tanganelli, I, Leonini, M, Egger, K, Marchiotto, W, Vincis, L, Orlandini, V, Pilloni, C, Farci, R, Pelligra, I, Renier, G, Mameli, M, Pala, A, Devigus, E, Fumagalli, I, Lalli, C, Leandri, M, Agliani, M, De Pascalis, L, Malci, F, De Ciocchis, A, Diodati, M, Macerola, B, Davi, S, Caccavale, A, Brocato, L, Pognant Gros, M, Borla, S, Lattanzi, E, Piersanti, C, Piersanti, A, Spinelli, I, Tuzzoli, L, Tulini, V, Quaranta, G, Iorio, V, Tirabovi, M, De Terlizi, C, Massarelli, M, Venturi, S, Travaglini, A, Draghi, P, Pomante, P, Richiardi, L, Clerico, A, Bruno, A, Cavallo Perin, P, Ghigo, E, Porta, M, Scuntero, P, Arcari, R, Bertaina, S, Bo, S, Broglio, F, Bruno, G, Degiovanni, M, Fornengo, P, Grassi, G, Inglese, V, Maccario, M, Maghenzani, G, Marena, S, Martina, V, Passera, P, Ruiu, G, Tagliabue, M, Zanone, M, Monge, M, Boffano, G, Macri, K, Maio, P, Ozzello, A, Pergolizzi, E, Gaia, D, Gennari, P, Micali, G, Rossetto, E, Dalmazzo, C, Oreglia, M, Stefani, T, Dossena, C, Paglia, P, Bosoni, S, Romanelli, T, Inchiostro, S, Dauriz, M, Bossi, C, Meregalli, G, Balini, A, Berzi, D, Filippini, B, Crotto, G, Paccagnella, A, Orrasch, M, Sambataro, M, Citro, T, Kiwanuka, E, Bagolin, E, Almoto, B, Macchia, A, Branca, M, Filesi, M, Candido, R, Caroli, E, Manca, E, Petrucco, A, Tommasi, E, Jagodnik, G, Baskar, B, Daris, N, Dal Col, P, Pellegrini, M, Tonutti, L, Venturini, G, Andreani, M, Turchi, F, Fedrighelli, F, Martinelli, G, Rongioletti, R, Candidi, M, Pais, M, Moro, E, Cervellino, F, Sinisi, R, Zampino, A, Mingardi, R, Lora, L, Reitano, R, Stocchiero, C, Simoncini, M, Mesturino, C, Zen, F, Di Pietro, S, Scoponi, C, Tilaro, L, Pelliccioni, S, Slongo, R, Vita, E, Garofalo, A, Vitale, F, Campanella, B, Mastrilli, V, Borrelli, T, D'Avino, A, Perbellini, A, Mirijello A., Viazzi F., Fioretto P., Giorda C. B., Ceriello A., Russo G. T., Guida P., Pontremoli R., De Cosmo S., Cimino A., Fava D., Meloncelli I., Nicolucci A., Pellegrini F., Rossi M. C., Turco S., Vespasiani G., Graziano G., Lucisano G., Memmo R., Pellicciotta E., Paciotti V., Pupillo M., Armentano G., Giovannini C., Armentano V., Laudato M., Acquati S., Ciardullo A. V., Laffi G., Felace G., Taboga C., Tortul C., Santantonio G., Suraci C., Ghisoni G., Raffa M., Genovese S., Lovagnini-Scher C. A., Rampini P., Rocca A., Ruggeri P., Tortato E., Cotti L., Cristofaro M. R., Tagliaferri M., Comoglio M., Fornengo R., Gentile F. M., Gigante A., Mastinu F., Di Benedetto A., Pata P., Arcangeli A., Orsini P., Acler P., De Blasi G., Cicioni G., Pocciati S., Marangoni A., Nogara A., Lanero M., Bertero M. G., Damassino R., Bergonzini C., Schumtz L., Seksich L., Pipitone A., Boaretto M., Manfroi I., Parmesan L., Conte B., Soccol F., Pagano A., Papini E., Rinaldi R., Petrucci L., Graziano F., Chianelli M., Silvagni S., Rosco M., Ansaldi E., Malvicino F., Battezzati M., Maresca P., Palenzona C., Boemi M., Rabini R. A., Brandoni G., Lanari L., Gatti C., Testa I., Cherubini V., Doveri G., Pecorelli L., Ciccarelli A., Gallardini M. B., Courthoud R., Sara Bredy S., Ricciardi G. P., Vitalone G., Setti D., Contrini P., Corsi A., Ghigliotti V., Oddone G., Ponzani P., Valbonesi G., Mazzini V., Di Berardino P., Colleluori P., Montani V., Trosini V., Velussi M., Alfidi P., Verdecchia B., Baliva L., Di Pietro A., Franchi G., Luce R. P., Pianta A., Ferrari M., Balzano S., Beltranello G., Dal Fabbro S., Arico C. N., Cervo L., Zanon R., Rossa S., Di Pace M. C., Ciavarella A., Giangiulio S., Grimaldi M., Mustacchio A., Fattor B., Monauni T., Cristini M., Orion G., Crazzolara D., Amor F., Eisath J. E., Lintner S., Garavelli S., Calari T., Marini P., Sandri O., Scala M., Stroppa C., Trentin A., Carlin R., Carli B., Sandona M., Zortea C., Bonet L., Pradel L., Reato S., Buschini M., Bonfiglioli D., Mones D., Beldi F., Morea A., Bondesan L., Perbellini S., Valentini U., Agosti B., Corsini R., Girelli A., Zarra E., Rocca L., Bergmann M., Pradi I., Unterkircher S., Piok M., Pichler M., Trinchera A., Palama G., Palma P., Carboni L., Murtas M. G., Mudadu T., Turco M. P., Floris M., Delogu A., Farris L., Songini M., Piras G., Seguro R., Floris R., Corona G., Lai M., Piras E., Contini P. P., Cocco S., Pilosu R. M., Sannia M. C., Spanu F., Busciantella Ricci N., Cartechini M. G., Agostinelli G., Fiorelli C., Nuzzi A., Ballauri C., Lesina A., Romeo F., Giudici G., Maciejewska E. G., Deroma A., Paduano M., Rossi L., Vagnini C., Dolci M., Mori M., Baccetti F., Gregori G., Straface E., Pozzuoli G., Barone M., Stasio G. B., Tondini S., Borgoni F., Grosso J., Scarsellato C., Sciulli A., De Marco F., Confortin L., Marin N., Lamonica M., Gialdino S., Borzi V., Gatta C., Rapisard R., Strano S., Calabro M., Puccio L., Zolli M., Coracina A., Starnone V., Del Buono A., Terracciano A. M., Monda M. V., Castro F., Guaglianone A., Maccari V., Corsi L., Versari G., Falivene M. R., Boletto N., Corsi S., Marafetti L., Vitacolonna E., Capani F., Caputo L., Di Nisio L., Simonetti F., Boscolo Bariga A., Ballarin G., De Boni S., Di Benedetto S., Chiambretti A. M., Di Vito L., Pascuzzo M. D., Urli P., Rumi P., Balzarini B., Galli P., Castellan M., Giannetti A., Russotti C., De Blasi A., Perna A., Campanelli C., Ranchelli A., Biccheri D., Dadi G., Massa L., Baldi G. P., Sciacca F., Costanzo E., Spada M., Paolini G., Ziller P., Portolan F., Pasolini G., Ghilardi G., Fiorina P., Grata M. L., Capretti L., Speroni G., Fugazza L., Massafra C., Lovagnini Scher A., Cimicchi M. C., Percudani C., Risolo T., Sacco P., Gidoni Guarnieri G. L., Piccolo D., Bravin C., De Noni E., Scarpel M., Marcon M., Giacon F., Panebianco G., Tadiotto F., Da Tos V., D'Ambrosio M., Pellizzola D., Zampini M. A., Frezzati E., Mari E., Raminelli E., Gaiti D., Bosi E. A., Chierici G., Pilla S., Copelli M., Zanichelli P., Bertelli L., Caretta P., Vezzani V., Bodecchi S., Longobucco A., Di Lembo S., Spotti E., Carrai E., Degli Innocenti A., Manini L., Persico R., Rossi C., Magro G., Marelli G., Vilei V., Andrioli M., Bellato L., Fedeli M., Merlini A., Pinelli G., Marin G., Contin M. L., Gallo A., Parlato P., Pecchielan W., Jacovacci J., Placentino G., Richini D., Molinari S., Strazzeri R., Fabbri T., Di Bartolo P., Garrapa G., D'Incau F., Lagomanzini P., Conte P., Todesco F., Foglini P., Pantanetti P., Bedetta C., Maricotti R., Tomasi F., Monesi M., Graziani R., Beretta F., Penna L., Guberti A., Dazzi D., Forte E., Gasbarrone A., Marrocco T., Moschetta R., Tuccinardi F., De Meo F., Coppola A., Pirolozzi P., Placitelli E., Vallefuoco R., Catone B., Ceschia S., Urban M., Fabbri F., Torresani M., Crovetto R., Battistini M., Carosia P., Viviani G. L., Durante A., Pais F., Lilliu V., Quieto C., D'Ugo E., Squadrone M., Amenduni T., Iovannisci M. M., Della Penna L., Potente F., Delle Donne T., Massa C., Ulisse M. A., De Berardinis S., Guarnieri I., Pace S., Splendiani M., Di Giuseppe R., Brunato B., Assaloni R., Muraro R., Loro R., Bucciol S., Lavacca C., Rossi M., Sabbatini G., Quadri F., Sambuco L., Santacroce C., Paola Caretta D., Marino C., Micheletti A., Petrelli A., Corda A., Pisano L., Guaita G., Deias C., Trevisan G., Coletti I., Iannarelli R., De Luca A., Minnucci A., Antenucci D., Di Florio C., Angelicola G., Bosco A., Fresco R., Di Marco G., Ugolotti D., Cadossi T., Di Caro P., Mazzocchetti M., Buzzetti R., Leto G., Gnessi C., Cipolloni L., Foffi C., Moretti C., Venditti C., Meniconi R., Bertoli S., Cosimi S., Di Cianni G., Turco A., Richini A., Marconi S., Sannino C., Lemmi P., Giuntoli S., Manfre N., Giannini F., Di Carlo A., Casadidio I., Melandri P., Maolo G., Polenta B., Piccinini N., Vincenti C., Pastore N., Mega P., Magurano E., Cananiello A., Francescutto C. A., Brussa Toi E., Gaspardo G., Angeli L., Ronchese L., Sciangula L., Ciucci A., Contartese A., Banfi E., Castelli E., Tatti P., Bloise D., Di Mauro P., Masselli L., Lo Presti A., Scarpitta A. M., Gambina F., Venezia A., Morea R., Lagonigro G., Copeta G., Iannucci V., Milano V., Trupo M., Lochmann A., Marchetto P. E., Incelli G., De Paola G., Steiger M. M., Gamper M. A., Breitenberger S., Holzner M., Frischmann J., Lambiase C., Di Vece T., D'Aniello M., Fezza M., Giordano C., Leo F., Saitta G., Cucinotta D., Di Vieste G., Pintaudi B., Mancuso T., Musacchio N., Giancaterini A., Pessina L., Salis G., Schivalocchi F., Testori G., Cerutti N., Morpugo P. S., Cavaletto M. L., Bonino G., Morreale F., Mariani G., Ragonesi P. D., Bollati P., Colapinto P., Falqui L., Bortolato L., Cosma A., Pistolato P., Centenaro B., Ceccato A., Campobasso G., Zaurino F., Mazzotta G., Manti R., Da Ros R., Carlucci S., Narduzzi L., Bortolotto D., D'Acunto L., Stanic L., Volpi A., Cospite A. M., Manicardi V., Michelini M., Finardi L., Borghi F., Manicardi E., Lombardi S., Tommasi C., Iaccarino M., Cozza S., Binotto M., Marini F., Mecenero I., Massignani S., Stecco P., Urbani E., Massariol W., Parolin R., Gatti A., Bonavita M., Creso E., Giannettino R., Gobbo M., Iovine C., Riccardi G., Iazzetta N., Giannattasio C., Egione O., Galdieri S., Velotti A., Azzolina A., Annicelli G., Sorrentino T., Gaeta I., Zenari L., Bertolini L., Sorgato C., Grippaldi F., Stroppiana M., Popolizio R., Carbone N., Grasso S., Abate S., Gaggero G. C., Strazzabosco M., Brun E., Carlesi G. P., Garrone S., Cicalo A. M., Clausi C., Cau R., Manconi A., Carboni A., Angius M. F., Pinna A. A., Caria S., Filigheddu G. D., Tonolo G., Carta I., Calebich S., Burlotti C., Saglietti G., Schellino A., Madau G., Cossu M., Mulas F., Zoccheddu S., Balsanelli M., Fetonti M., Rotolo A., Sambo P., Secchi E., Angotzi M. A., Loddoni S., Brundu I., Careddu F., Becciu A., Gabriella Piras G., Novara F., Cipro F., Torchio G., Palumbo P., Bianchi A., Colucci G., La Motta G., Tiengo A., Avogaro A., Bruttomesso D., Crepaldi C., Fadini G., Guarnieri G., Lavagnini M. T., Maran A., Vedovato M., De Kreutzenberg V., Fedele D., Lapolla A., Sartore G., Bax G., Cardone C., Dalfra M. G., Masin M., Toniato R., Piarulli F., Mattina G., Fulantelli M. A., Gioia D., Conti M., Ridola G., D'Agati F., Grossi G., Zavaroni I., Dei Cas A., Franzini L., Usberti E., Antonimi M., Anelli N., Poli R., Ridolfi V., Michela M., Haddoub S., Prampolini G., Muoio A., Filippi D., Bucci F., Tardio S. M., Calderini M. C., Magotti M. G., Quarantelli C., Vernazza M. A., Carolfi A., Saracca R., Picchio E., Del Sindaco P., Spalluto A., Maggiulli L., Torreggiani V., Rastelletti S., Ugolini C., Pucci N., Magi S., Muratori S., La Penna G., Consoli A., Galeone F., Magiar A. V., Gherardini V., Moretti L., Bientinesi M., Landi L., Bernardi A., Del Prato S., Miccoli R., Bianchi C., Penno G., Venditti F., Anichini R., De Bellis A., Bruschi T., Butelli L., Gioffredi M., Gori R., Picciafuochi R., Malagoli R., Bernini A., Gelisio R., Zanon M., Del Bianco A., Bamiston A., Signorato M., Citro G., Calabrese M., Ianni L., Lorenzetti M., Marsocci A., Guizzotti S., Memoli G., Cabasino F., Farci F., Atzori A., Sanna A., Ghiani M., Siotto I., Sedda M., Manis A., Loddo C., Loddo I., Seguro P., Cuomo A., Orlando L., Olanda G. B., Pucci A., Massenzo M., Sardu C., Perrone G., Corazziere F., La Puzza I., Tripodi P. F., Riggio S., Giampaolo A., Mannino D., Aleandri A. R., Guidi M. V., Battisti B., Faraglia M. R., Lilli V., Leotta S., Visalli N., Gagliardi A., Fontana L., Altomare M., Carletti S., Abbruzzese S., Chiaramonte F., Giordano R., Rossini M., Migneco G., Cappelloni D., Urbani A., Piergiovanni F., Simonetta A., Massimiani F., Bulzomi R., Giuliano M., Pennafina M. 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A., Fancellu A., Bianco P., Lione L., Massazza G., Bocchio G., Bosco E., Monachesi M., Carta G., Boschetti M., Ceresola E., Venier E., Calcaterra F., Cataldi F., Miola M., Manfrini S., Lai A., Locci B., Putzu D., Tanganelli I., Leonini M., Egger K., Marchiotto W., Vincis L., Orlandini V., Pilloni C., Farci R., Pelligra I., Renier G., Mameli M., Pala A., Devigus E., Fumagalli I., Lalli C., Leandri M., Agliani M., De Pascalis L., Malci F., De Ciocchis A., Diodati M. B., Macerola B., Davi S., Caccavale A., Brocato L., Pognant Gros M., Borla S., Lattanzi E., Piersanti C., Piersanti A., Spinelli I., Tuzzoli L., Tulini V., Quaranta G., Iorio V., Tirabovi M., De Terlizi C., Massarelli M. 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Sciangula, L, Ciucci, A, Contartese, A, Banfi, E, Castelli, E, Tatti, P, Bloise, D, Di Mauro, P, Masselli, L, Lo Presti, A, Scarpitta, A, Gambina, F, Venezia, A, Morea, R, Lagonigro, G, Copeta, G, Iannucci, V, Milano, V, Trupo, M, Lochmann, A, Marchetto, P, Incelli, G, De Paola, G, Steiger, M, Gamper, M, Breitenberger, S, Holzner, M, Frischmann, J, Lambiase, C, Di Vece, T, D'Aniello, M, Fezza, M, Giordano, C, Leo, F, Saitta, G, Cucinotta, D, Di Vieste, G, Pintaudi, B, Mancuso, T, Musacchio, N, Giancaterini, A, Pessina, L, Salis, G, Schivalocchi, F, Testori, G, Cerutti, N, Morpugo, P, Cavaletto, M, Bonino, G, Morreale, F, Mariani, G, Ragonesi, P, Bollati, P, Colapinto, P, Falqui, L, Bortolato, L, Cosma, A, Pistolato, P, Centenaro, B, Ceccato, A, Campobasso, G, Zaurino, F, Mazzotta, G, Manti, R, Da Ros, R, Carlucci, S, Narduzzi, L, Bortolotto, D, D'Acunto, L, Stanic, L, Volpi, A, Cospite, A, Manicardi, V, Michelini, M, Finardi, L, Borghi, F, Manicardi, E, Lombardi, S, Tommasi, C, 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Guarnieri, G, Lavagnini, M, Maran, A, Vedovato, M, De Kreutzenberg, V, Fedele, D, Lapolla, A, Sartore, G, Bax, G, Cardone, C, Dalfra, M, Masin, M, Toniato, R, Piarulli, F, Mattina, G, Fulantelli, M, Gioia, D, Conti, M, Ridola, G, D'Agati, F, Grossi, G, Zavaroni, I, Dei Cas, A, Franzini, L, Usberti, E, Antonimi, M, Anelli, N, Poli, R, Ridolfi, V, Michela, M, Haddoub, S, Prampolini, G, Muoio, A, Filippi, D, Bucci, F, Tardio, S, Calderini, M, Magotti, M, Quarantelli, C, Vernazza, M, Carolfi, A, Saracca, R, Picchio, E, Del Sindaco, P, Spalluto, A, Maggiulli, L, Torreggiani, V, Rastelletti, S, Ugolini, C, Pucci, N, Magi, S, Muratori, S, La Penna, G, Consoli, A, Galeone, F, Magiar, A, Gherardini, V, Moretti, L, Bientinesi, M, Landi, L, Bernardi, A, Del Prato, S, Miccoli, R, Bianchi, C, Penno, G, Venditti, F, Anichini, R, De Bellis, A, Bruschi, T, Butelli, L, Gioffredi, M, Gori, R, Picciafuochi, R, Malagoli, R, Bernini, A, Gelisio, R, Zanon, M, Del Bianco, A, Bamiston, A, Signorato, M, Citro, G, Calabrese, M, Ianni, L, Lorenzetti, M, Marsocci, A, Guizzotti, S, Memoli, G, Cabasino, F, Farci, F, Atzori, A, Sanna, A, Ghiani, M, Siotto, I, Sedda, M, Manis, A, Loddo, C, Loddo, I, Seguro, P, Cuomo, A, Orlando, L, Olanda, G, Pucci, A, Massenzo, M, Sardu, C, Perrone, G, Corazziere, F, La Puzza, I, Tripodi, P, Riggio, S, Giampaolo, A, Mannino, D, Aleandri, A, Guidi, M, Battisti, B, Faraglia, M, Lilli, V, Leotta, S, Visalli, N, Gagliardi, A, Fontana, L, Altomare, M, Carletti, S, Abbruzzese, S, Chiaramonte, F, Giordano, R, Rossini, M, Migneco, G, Cappelloni, D, Urbani, A, Piergiovanni, F, Simonetta, A, Massimiani, F, Bulzomi, R, Giuliano, M, Pennafina, M, Di Perna, P, D'Accinni, M, Paolucci, D, D'Ubaldi, A, D'Angelo, M, Masaro, G, Pietrantoni, M, Fratini, M, La Rosa, R, Poggi, M, Piccirilli, F, Pisano, R, Saponara, C, Conforti, I, Penza, A, Scalpone, R, Lo Pinto, S, Iacovella, L, Caccamo, C, Sposito, S, Teodonio, C, Restuccia, M, Mirto, G, Girardello, R, Gennaro, R, De Moliner, L, Bettini, E, Mattuzzi, A, Speese, K, Frisinghelli, F, Locatelli, F, Nicoletti, M, Trojan, N, Centis, R, L Volsi, P, Levis, E, Zanette, G, Comba, G, Ballatore, L, Cattaneo, A, Aglialoro, A, Guido, R, Patrone, M, Zecchini, M, Clementi, L, Galetta, M, Marconi, V, Bordin, P, Perale, L, Vinci, C, Sira Zanon, M, Geretto, L, Toffolo, C, Furlan, M, Mazzanti, G, Vinci, M, Sica, V, Armeni, M, Derai, R, Ennas, O, Mamusa, S, Pisano, M, Carreras, L, Rauseo, A, Cervone, S, Leggieri, A, Pontonio, M, Sturaro, R, Quattrocchi, F, Molinaro, M, Trasatti, M, Ferretti, B, Labarile, G, Baule, G, Gentilini, A, Spanu, M, Fancellu, A, Bianco, P, Lione, L, Massazza, G, Bocchio, G, Bosco, E, Monachesi, M, Carta, G, Boschetti, M, Ceresola, E, Venier, E, Calcaterra, F, Cataldi, F, Miola, M, Manfrini, S, Lai, A, Locci, B, Putzu, D, Tanganelli, I, Leonini, M, Egger, K, Marchiotto, W, Vincis, L, Orlandini, V, Pilloni, C, Farci, R, Pelligra, I, Renier, G, Mameli, M, Pala, A, Devigus, E, Fumagalli, I, Lalli, C, Leandri, M, Agliani, M, De Pascalis, L, Malci, F, De Ciocchis, A, Diodati, M, Macerola, B, Davi, S, Caccavale, A, Brocato, L, Pognant Gros, M, Borla, S, Lattanzi, E, Piersanti, C, Piersanti, A, Spinelli, I, Tuzzoli, L, Tulini, V, Quaranta, G, Iorio, V, Tirabovi, M, De Terlizi, C, Massarelli, M, Venturi, S, Travaglini, A, Draghi, P, Pomante, P, Richiardi, L, Clerico, A, Bruno, A, Cavallo Perin, P, Ghigo, E, Porta, M, Scuntero, P, Arcari, R, Bertaina, S, Bo, S, Broglio, F, Bruno, G, Degiovanni, M, Fornengo, P, Grassi, G, Inglese, V, Maccario, M, Maghenzani, G, Marena, S, Martina, V, Passera, P, Ruiu, G, Tagliabue, M, Zanone, M, Monge, M, Boffano, G, Macri, K, Maio, P, Ozzello, A, Pergolizzi, E, Gaia, D, Gennari, P, Micali, G, Rossetto, E, Dalmazzo, C, Oreglia, M, Stefani, T, Dossena, C, Paglia, P, Bosoni, S, Romanelli, T, Inchiostro, S, Dauriz, M, Bossi, C, Meregalli, G, Balini, A, Berzi, D, Filippini, B, Crotto, G, Paccagnella, A, Orrasch, M, Sambataro, M, Citro, T, Kiwanuka, E, Bagolin, E, Almoto, B, Macchia, A, Branca, M, Filesi, M, Candido, R, Caroli, E, Manca, E, Petrucco, A, Tommasi, E, Jagodnik, G, Baskar, B, Daris, N, Dal Col, P, Pellegrini, M, Tonutti, L, Venturini, G, Andreani, M, Turchi, F, Fedrighelli, F, Martinelli, G, Rongioletti, R, Candidi, M, Pais, M, Moro, E, Cervellino, F, Sinisi, R, Zampino, A, Mingardi, R, Lora, L, Reitano, R, Stocchiero, C, Simoncini, M, Mesturino, C, Zen, F, Di Pietro, S, Scoponi, C, Tilaro, L, Pelliccioni, S, Slongo, R, Vita, E, Garofalo, A, Vitale, F, Campanella, B, Mastrilli, V, Borrelli, T, D'Avino, A, Perbellini, A, Mirijello A., Viazzi F., Fioretto P., Giorda C. B., Ceriello A., Russo G. T., Guida P., Pontremoli R., De Cosmo S., Cimino A., Fava D., Meloncelli I., Nicolucci A., Pellegrini F., Rossi M. C., Turco S., Vespasiani G., Graziano G., Lucisano G., Memmo R., Pellicciotta E., Paciotti V., Pupillo M., Armentano G., Giovannini C., Armentano V., Laudato M., Acquati S., Ciardullo A. V., Laffi G., Felace G., Taboga C., Tortul C., Santantonio G., Suraci C., Ghisoni G., Raffa M., Genovese S., Lovagnini-Scher C. A., Rampini P., Rocca A., Ruggeri P., Tortato E., Cotti L., Cristofaro M. R., Tagliaferri M., Comoglio M., Fornengo R., Gentile F. M., Gigante A., Mastinu F., Di Benedetto A., Pata P., Arcangeli A., Orsini P., Acler P., De Blasi G., Cicioni G., Pocciati S., Marangoni A., Nogara A., Lanero M., Bertero M. G., Damassino R., Bergonzini C., Schumtz L., Seksich L., Pipitone A., Boaretto M., Manfroi I., Parmesan L., Conte B., Soccol F., Pagano A., Papini E., Rinaldi R., Petrucci L., Graziano F., Chianelli M., Silvagni S., Rosco M., Ansaldi E., Malvicino F., Battezzati M., Maresca P., Palenzona C., Boemi M., Rabini R. A., Brandoni G., Lanari L., Gatti C., Testa I., Cherubini V., Doveri G., Pecorelli L., Ciccarelli A., Gallardini M. B., Courthoud R., Sara Bredy S., Ricciardi G. P., Vitalone G., Setti D., Contrini P., Corsi A., Ghigliotti V., Oddone G., Ponzani P., Valbonesi G., Mazzini V., Di Berardino P., Colleluori P., Montani V., Trosini V., Velussi M., Alfidi P., Verdecchia B., Baliva L., Di Pietro A., Franchi G., Luce R. P., Pianta A., Ferrari M., Balzano S., Beltranello G., Dal Fabbro S., Arico C. N., Cervo L., Zanon R., Rossa S., Di Pace M. C., Ciavarella A., Giangiulio S., Grimaldi M., Mustacchio A., Fattor B., Monauni T., Cristini M., Orion G., Crazzolara D., Amor F., Eisath J. E., Lintner S., Garavelli S., Calari T., Marini P., Sandri O., Scala M., Stroppa C., Trentin A., Carlin R., Carli B., Sandona M., Zortea C., Bonet L., Pradel L., Reato S., Buschini M., Bonfiglioli D., Mones D., Beldi F., Morea A., Bondesan L., Perbellini S., Valentini U., Agosti B., Corsini R., Girelli A., Zarra E., Rocca L., Bergmann M., Pradi I., Unterkircher S., Piok M., Pichler M., Trinchera A., Palama G., Palma P., Carboni L., Murtas M. G., Mudadu T., Turco M. P., Floris M., Delogu A., Farris L., Songini M., Piras G., Seguro R., Floris R., Corona G., Lai M., Piras E., Contini P. P., Cocco S., Pilosu R. M., Sannia M. C., Spanu F., Busciantella Ricci N., Cartechini M. G., Agostinelli G., Fiorelli C., Nuzzi A., Ballauri C., Lesina A., Romeo F., Giudici G., Maciejewska E. G., Deroma A., Paduano M., Rossi L., Vagnini C., Dolci M., Mori M., Baccetti F., Gregori G., Straface E., Pozzuoli G., Barone M., Stasio G. B., Tondini S., Borgoni F., Grosso J., Scarsellato C., Sciulli A., De Marco F., Confortin L., Marin N., Lamonica M., Gialdino S., Borzi V., Gatta C., Rapisard R., Strano S., Calabro M., Puccio L., Zolli M., Coracina A., Starnone V., Del Buono A., Terracciano A. M., Monda M. V., Castro F., Guaglianone A., Maccari V., Corsi L., Versari G., Falivene M. R., Boletto N., Corsi S., Marafetti L., Vitacolonna E., Capani F., Caputo L., Di Nisio L., Simonetti F., Boscolo Bariga A., Ballarin G., De Boni S., Di Benedetto S., Chiambretti A. M., Di Vito L., Pascuzzo M. D., Urli P., Rumi P., Balzarini B., Galli P., Castellan M., Giannetti A., Russotti C., De Blasi A., Perna A., Campanelli C., Ranchelli A., Biccheri D., Dadi G., Massa L., Baldi G. P., Sciacca F., Costanzo E., Spada M., Paolini G., Ziller P., Portolan F., Pasolini G., Ghilardi G., Fiorina P., Grata M. L., Capretti L., Speroni G., Fugazza L., Massafra C., Lovagnini Scher A., Cimicchi M. C., Percudani C., Risolo T., Sacco P., Gidoni Guarnieri G. L., Piccolo D., Bravin C., De Noni E., Scarpel M., Marcon M., Giacon F., Panebianco G., Tadiotto F., Da Tos V., D'Ambrosio M., Pellizzola D., Zampini M. A., Frezzati E., Mari E., Raminelli E., Gaiti D., Bosi E. A., Chierici G., Pilla S., Copelli M., Zanichelli P., Bertelli L., Caretta P., Vezzani V., Bodecchi S., Longobucco A., Di Lembo S., Spotti E., Carrai E., Degli Innocenti A., Manini L., Persico R., Rossi C., Magro G., Marelli G., Vilei V., Andrioli M., Bellato L., Fedeli M., Merlini A., Pinelli G., Marin G., Contin M. L., Gallo A., Parlato P., Pecchielan W., Jacovacci J., Placentino G., Richini D., Molinari S., Strazzeri R., Fabbri T., Di Bartolo P., Garrapa G., D'Incau F., Lagomanzini P., Conte P., Todesco F., Foglini P., Pantanetti P., Bedetta C., Maricotti R., Tomasi F., Monesi M., Graziani R., Beretta F., Penna L., Guberti A., Dazzi D., Forte E., Gasbarrone A., Marrocco T., Moschetta R., Tuccinardi F., De Meo F., Coppola A., Pirolozzi P., Placitelli E., Vallefuoco R., Catone B., Ceschia S., Urban M., Fabbri F., Torresani M., Crovetto R., Battistini M., Carosia P., Viviani G. L., Durante A., Pais F., Lilliu V., Quieto C., D'Ugo E., Squadrone M., Amenduni T., Iovannisci M. M., Della Penna L., Potente F., Delle Donne T., Massa C., Ulisse M. A., De Berardinis S., Guarnieri I., Pace S., Splendiani M., Di Giuseppe R., Brunato B., Assaloni R., Muraro R., Loro R., Bucciol S., Lavacca C., Rossi M., Sabbatini G., Quadri F., Sambuco L., Santacroce C., Paola Caretta D., Marino C., Micheletti A., Petrelli A., Corda A., Pisano L., Guaita G., Deias C., Trevisan G., Coletti I., Iannarelli R., De Luca A., Minnucci A., Antenucci D., Di Florio C., Angelicola G., Bosco A., Fresco R., Di Marco G., Ugolotti D., Cadossi T., Di Caro P., Mazzocchetti M., Buzzetti R., Leto G., Gnessi C., Cipolloni L., Foffi C., Moretti C., Venditti C., Meniconi R., Bertoli S., Cosimi S., Di Cianni G., Turco A., Richini A., Marconi S., Sannino C., Lemmi P., Giuntoli S., Manfre N., Giannini F., Di Carlo A., Casadidio I., Melandri P., Maolo G., Polenta B., Piccinini N., Vincenti C., Pastore N., Mega P., Magurano E., Cananiello A., Francescutto C. A., Brussa Toi E., Gaspardo G., Angeli L., Ronchese L., Sciangula L., Ciucci A., Contartese A., Banfi E., Castelli E., Tatti P., Bloise D., Di Mauro P., Masselli L., Lo Presti A., Scarpitta A. M., Gambina F., Venezia A., Morea R., Lagonigro G., Copeta G., Iannucci V., Milano V., Trupo M., Lochmann A., Marchetto P. E., Incelli G., De Paola G., Steiger M. M., Gamper M. A., Breitenberger S., Holzner M., Frischmann J., Lambiase C., Di Vece T., D'Aniello M., Fezza M., Giordano C., Leo F., Saitta G., Cucinotta D., Di Vieste G., Pintaudi B., Mancuso T., Musacchio N., Giancaterini A., Pessina L., Salis G., Schivalocchi F., Testori G., Cerutti N., Morpugo P. S., Cavaletto M. L., Bonino G., Morreale F., Mariani G., Ragonesi P. D., Bollati P., Colapinto P., Falqui L., Bortolato L., Cosma A., Pistolato P., Centenaro B., Ceccato A., Campobasso G., Zaurino F., Mazzotta G., Manti R., Da Ros R., Carlucci S., Narduzzi L., Bortolotto D., D'Acunto L., Stanic L., Volpi A., Cospite A. M., Manicardi V., Michelini M., Finardi L., Borghi F., Manicardi E., Lombardi S., Tommasi C., Iaccarino M., Cozza S., Binotto M., Marini F., Mecenero I., Massignani S., Stecco P., Urbani E., Massariol W., Parolin R., Gatti A., Bonavita M., Creso E., Giannettino R., Gobbo M., Iovine C., Riccardi G., Iazzetta N., Giannattasio C., Egione O., Galdieri S., Velotti A., Azzolina A., Annicelli G., Sorrentino T., Gaeta I., Zenari L., Bertolini L., Sorgato C., Grippaldi F., Stroppiana M., Popolizio R., Carbone N., Grasso S., Abate S., Gaggero G. C., Strazzabosco M., Brun E., Carlesi G. P., Garrone S., Cicalo A. M., Clausi C., Cau R., Manconi A., Carboni A., Angius M. F., Pinna A. A., Caria S., Filigheddu G. D., Tonolo G., Carta I., Calebich S., Burlotti C., Saglietti G., Schellino A., Madau G., Cossu M., Mulas F., Zoccheddu S., Balsanelli M., Fetonti M., Rotolo A., Sambo P., Secchi E., Angotzi M. A., Loddoni S., Brundu I., Careddu F., Becciu A., Gabriella Piras G., Novara F., Cipro F., Torchio G., Palumbo P., Bianchi A., Colucci G., La Motta G., Tiengo A., Avogaro A., Bruttomesso D., Crepaldi C., Fadini G., Guarnieri G., Lavagnini M. T., Maran A., Vedovato M., De Kreutzenberg V., Fedele D., Lapolla A., Sartore G., Bax G., Cardone C., Dalfra M. G., Masin M., Toniato R., Piarulli F., Mattina G., Fulantelli M. A., Gioia D., Conti M., Ridola G., D'Agati F., Grossi G., Zavaroni I., Dei Cas A., Franzini L., Usberti E., Antonimi M., Anelli N., Poli R., Ridolfi V., Michela M., Haddoub S., Prampolini G., Muoio A., Filippi D., Bucci F., Tardio S. M., Calderini M. C., Magotti M. G., Quarantelli C., Vernazza M. A., Carolfi A., Saracca R., Picchio E., Del Sindaco P., Spalluto A., Maggiulli L., Torreggiani V., Rastelletti S., Ugolini C., Pucci N., Magi S., Muratori S., La Penna G., Consoli A., Galeone F., Magiar A. V., Gherardini V., Moretti L., Bientinesi M., Landi L., Bernardi A., Del Prato S., Miccoli R., Bianchi C., Penno G., Venditti F., Anichini R., De Bellis A., Bruschi T., Butelli L., Gioffredi M., Gori R., Picciafuochi R., Malagoli R., Bernini A., Gelisio R., Zanon M., Del Bianco A., Bamiston A., Signorato M., Citro G., Calabrese M., Ianni L., Lorenzetti M., Marsocci A., Guizzotti S., Memoli G., Cabasino F., Farci F., Atzori A., Sanna A., Ghiani M., Siotto I., Sedda M., Manis A., Loddo C., Loddo I., Seguro P., Cuomo A., Orlando L., Olanda G. B., Pucci A., Massenzo M., Sardu C., Perrone G., Corazziere F., La Puzza I., Tripodi P. F., Riggio S., Giampaolo A., Mannino D., Aleandri A. R., Guidi M. V., Battisti B., Faraglia M. R., Lilli V., Leotta S., Visalli N., Gagliardi A., Fontana L., Altomare M., Carletti S., Abbruzzese S., Chiaramonte F., Giordano R., Rossini M., Migneco G., Cappelloni D., Urbani A., Piergiovanni F., Simonetta A., Massimiani F., Bulzomi R., Giuliano M., Pennafina M. G., Di Perna P., D'Accinni M. P., Paolucci D., D'Ubaldi A., D'Angelo M. T., Masaro G., Pietrantoni M., Fratini M., La Rosa R., Poggi M., Piccirilli F., Pisano R., Saponara C., Conforti I., Penza A., Scalpone R., Lo Pinto S., Iacovella L., Caccamo C., Sposito S., Teodonio C., Restuccia M. G., Mirto G., Girardello R., Gennaro R., De Moliner L., Bettini E., Mattuzzi A., Speese K., Frisinghelli F., Locatelli F., Nicoletti M., Trojan N., Centis R., L Volsi P., Levis E., Zanette G., Comba G., Ballatore L., Cattaneo A., Aglialoro A., Guido R., Patrone M., Zecchini M., Clementi L., Galetta M., Marconi V., Bordin P., Perale L., Vinci C., Sira Zanon M., Geretto L., Toffolo C., Furlan M. G., Mazzanti G., Vinci M., Sica V., Armeni M., Derai R., Ennas O., Mamusa S., Pisano M. A., Carreras L., Rauseo A., Cervone S., Leggieri A., Pontonio M., Sturaro R., Quattrocchi F., Molinaro M., Trasatti M., Ferretti B., Labarile G., Baule G. M., Gentilini A., Spanu M. A., Fancellu A., Bianco P., Lione L., Massazza G., Bocchio G., Bosco E., Monachesi M., Carta G., Boschetti M., Ceresola E., Venier E., Calcaterra F., Cataldi F., Miola M., Manfrini S., Lai A., Locci B., Putzu D., Tanganelli I., Leonini M., Egger K., Marchiotto W., Vincis L., Orlandini V., Pilloni C., Farci R., Pelligra I., Renier G., Mameli M., Pala A., Devigus E., Fumagalli I., Lalli C., Leandri M., Agliani M., De Pascalis L., Malci F., De Ciocchis A., Diodati M. B., Macerola B., Davi S., Caccavale A., Brocato L., Pognant Gros M., Borla S., Lattanzi E., Piersanti C., Piersanti A., Spinelli I., Tuzzoli L., Tulini V., Quaranta G., Iorio V., Tirabovi M., De Terlizi C., Massarelli M. G., Venturi S., Travaglini A., Draghi P., Pomante P., Richiardi L., Clerico A., Bruno A., Cavallo Perin P., Ghigo E., Porta M., Scuntero P., Arcari R., Bertaina S., Bo S., Broglio F., Bruno G., Degiovanni M., Fornengo P., Grassi G., Inglese V., Maccario M., Maghenzani G., Marena S., Martina V., Passera P., Ruiu G., Tagliabue M., Zanone M., Monge M., Boffano G. M., Macri K., Maio P., Ozzello A., Pergolizzi E., Gaia D., Gennari P., Micali G., Rossetto E., Dalmazzo C., Oreglia M., Stefani T., Dossena C., Paglia P., Bosoni S., Romanelli T., Inchiostro S., Dauriz M., Bossi C. A., Meregalli G., Balini A., Berzi D., Filippini B., Crotto G., Paccagnella A., Orrasch M., Sambataro M., Citro T., Kiwanuka E., Bagolin E., Almoto B., Macchia A., Branca M. T., Filesi M., Candido R., Caroli E., Manca E., Petrucco A., Tommasi E., Jagodnik G., Baskar B., Daris N., Dal Col P., Pellegrini M. A., Tonutti L., Venturini G., Andreani M., Turchi F., Fedrighelli F., Martinelli G., Rongioletti R., Candidi M., Pais M., Moro E., Cervellino F., Sinisi R., Zampino A., Mingardi R., Lora L., Reitano R., Stocchiero C., Simoncini M., Mesturino C. A., Zen F., Di Pietro S., Scoponi C., Tilaro L., Pelliccioni S., Slongo R., Vita E., Garofalo A., Vitale F., Campanella B., Mastrilli V., Borrelli T., D'Avino A., and Perbellini A.
- Abstract
Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage ≥3 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 ± 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage ≥3 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage ≥3 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening.
- Published
- 2018
6. Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes 11 Medical and Health Sciences 1103 Clinical Sciences
- Author
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Mirijello, Antonio, Viazzi, Francesca, Fioretto, Paola, Giorda, C. B., Ceriello, Antonio, Russo, Giuspina T., Guida, Pietro, Pontremoli, Roberto, De Cosmo, S., Cimino, Antonino, Fava, Danila, Meloncelli, Illidio, Nicolucci, Antonio, Pellegrini, Fabio, Rossi, Maria Chiara, Turco, Salvatore, Vespasiani, Giacomo, Graziano, G., Lucisano, G., Memmo, R., Pellicciotta, E., Paciotti, V., Pupillo, M., Armentano, G., Giovannini, C., Armentano, V., Laudato, M., Acquati, S., Ciardullo, A. V., Laffi, G., Felace, G., Taboga, C., Tortul, C., Santantonio, G., Suraci, C., Ghisoni, G., Raffa, M., Genovese, S., Lovagnini-Scher, C. A., Rampini, P., Rocca, A., Ruggeri, P., Tortato, E., Cotti, L., Cristofaro, M. R., Tagliaferri, M., Comoglio, M., Fornengo, R., Gentile, F. M., Gigante, Antonio, Mastinu, F., Di Benedetto, A., Pata, P., Arcangeli, A., Orsini, P., Acler, P., De Blasi, G., Cicioni, G., Pocciati, S., Marangoni, A., Nogara, A., Lanero, M., Bertero, M. G., Damassino, R., Bergonzini, C., Schumtz, L., Seksich, L., Pipitone, A., Boaretto, M., Manfroi, I., Parmesan, L., Conte, B., Soccol, F., Pagano, A., Papini, E., Rinaldi, R., Petrucci, L., Graziano, F., Chianelli, M., Silvagni, S., Rosco, M., Ansaldi, E., Malvicino, F., Battezzati, M., Maresca, P., Palenzona, C., Boemi, M., Rabini, R. A., Brandoni, G., Lanari, L., Gatti, C., Testa, I., Cherubini, V., Doveri, G., Pecorelli, L., Ciccarelli, A., Gallardini, M. B., Courthoud, R., Sara Bredy, S., Ricciardi, G. P., Vitalone, G., Setti, D., Contrini, P., Corsi, A., Ghigliotti, V., Oddone, G., Ponzani, P., Valbonesi, G., Mazzini, V., Di Berardino, P., Colleluori, P., Montani, V., Trosini, V., Velussi, M., Alfidi, P., Verdecchia, B., Baliva, L., Di Pietro, A., Franchi, G., Luce, R. P., Pianta, A., Ferrari, M., Balzano, S., Beltranello, G., Dal Fabbro, S., Aricò, C. N., Cervo, L., Zanon, R., Rossa, S., Di Pace, M. 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M., Clausi, C., Cau, R., Manconi, A., Carboni, A., Angius, M. F., Pinna, A. A., Caria, S., Filigheddu, G. D., Tonolo, G., Carta, I., Calebich, S., Burlotti, C., Saglietti, G., Schellino, A., Madau, G., Cossu, M., Mulas, F., Zoccheddu, S., Balsanelli, M., Fetonti, M., Rotolo, A., Sambo, P., Secchi, E., Angotzi, M. A., Loddoni, S., Brundu, I., Careddu, F., Becciu, A., Gabriella Piras, G., Novara, F., Cipro, F., Torchio, G., Palumbo, P., Bianchi, A., Colucci, G., La Motta, G., Tiengo, A., Avogaro, A., Bruttomesso, D., Crepaldi, C., Fadini, G., Guarnieri, G., Lavagnini, M. T., Maran, A., Vedovato, M., De Kreutzenberg, V., Fedele, D., Lapolla, A., Sartore, G., Bax, G., Cardone, C., Dalfrà, M. G., Masin, M., Toniato, R., Piarulli, Francesco, Mattina, G., Fulantelli, M. A., Gioia, D., Conti, M., Ridola, G., D'Agati, F., Grossi, G., Zavaroni, I., Dei Cas, A., Franzini, L., Usberti, E., Antonimi, M., Anelli, N., Poli, R., Ridolfi, V., Michela, M., Haddoub, S., Prampolini, G., Muoio, A., Filippi, D., Bucci, F., Tardio, S. M., Calderini, M. C., Magotti, M. G., Quarantelli, C., Vernazza, M. A., Carolfi, A., Saracca, R., Picchio, E., Del Sindaco, P., Spalluto, A., Maggiulli, L., Torreggiani, V., Rastelletti, S., Ugolini, C., Pucci, N., Magi, S., Muratori, S., La Penna, G., Consoli, A., Galeone, F., Magiar, A. 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- Subjects
Albuminuria ,Diabetic kidney disease ,GFR ,Albuminuria, Diabetic kidney disease, GFR ,Nephrology - Abstract
Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage ≥3 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 ± 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage ≥3 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage ≥3 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening.
- Published
- 2018
7. Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes
- Author
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Mirijello, Antonio, Viazzi, Francesca, Fioretto, Paola, Giorda, Carlo, Ceriello, Antonio, Russo, Giuspina T., Guida, Pietro, Pontremoli, Roberto, De Cosmo, Salvatore, Cimino, Antonino, Fava, Danila, Giorda, Carlo Bruno, Meloncelli, Illidio, Nicolucci, Antonio, Pellegrini, Fabio, Rossi, Maria Chiara, Turco, Salvatore, Vespasiani, Giacomo, Pellegrini, F., Graziano, G., Lucisano, G., Memmo, R., Pellicciotta, E., Paciotti, V., Pupillo, M., Armentano, G., Giovannini, C., Armentano, V., Laudato, M., Turco, S., Acquati, S., Ciardullo, A. V., Laffi, G., Felace, G., Taboga, C., Tortul, C., Santantonio, G., Suraci, C., Ghisoni, G., Raffa, M., Genovese, S., Lovagnini-Scher, C. A., Rampini, P., Rocca, A., Ruggeri, P., Tortato, E., Cotti, L., Cristofaro, M. R., Tagliaferri, M., Comoglio, M., Fornengo, R., De Cosmo, S., Gentile, F. M., Gigante, A., Mastinu, F., Di Benedetto, A., Pata, P., Arcangeli, A., Orsini, P., Acler, P., De Blasi, G., Cicioni, G., Pocciati, S., Marangoni, A., Nogara, A., Lanero, M., Bertero, M. G., Damassino, R., Bergonzini, C., Schumtz, L., Seksich, L., Pipitone, A., Boaretto, M., Manfroi, I., Parmesan, L., Conte, B., Soccol, F., Pagano, A., Papini, E., Rinaldi, R., Petrucci, L., Graziano, F., Chianelli, M., Silvagni, S., Rosco, M., Ansaldi, E., Malvicino, F., Battezzati, M., Maresca, P., Palenzona, C., Boemi, M., Rabini, R. A., Brandoni, G., Lanari, L., Gatti, C., Testa, I., Cherubini, V., Doveri, G., Pecorelli, L., Ciccarelli, A., Gallardini, M. B., Courthoud, R., Sara Bredy, S., Ricciardi, G. P., Vitalone, G., Setti, D., Contrini, P., Corsi, A., Ghigliotti, V., Oddone, G., Ponzani, P., Valbonesi, G., Mazzini, V., Di Berardino, P., Colleluori, P., Montani, V., Trosini, V., Velussi, M., Alfidi, P., Verdecchia, B., Baliva, L., Di Pietro, A., Franchi, G., Luce, R. 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C., Spanu, F., Busciantella Ricci, N., Cartechini, M. G., Agostinelli, G., Fiorelli, C., Nuzzi, A., Ballauri, C., Giorda, C. B., Lesina, A., Romeo, F., Giudici, G., Maciejewska, E. G., Deroma, A., Paduano, M., Rossi, L., Vagnini, C., Dolci, M., Mori, M., Baccetti, F., Gregori, G., Straface, E., Pozzuoli, G., Barone, M., Stasio, G. B., Tondini, S., Borgoni, F., Grosso, J., Scarsellato, C., Sciulli, A., De Marco, F., Confortin, L., Marin, N., Lamonica, M., Gialdino, S., Borzì, V., Gatta, C., Rapisard, R., Strano, S., Calabrò, M., Puccio, L., Zolli, M., Coracina, A., Starnone, V., Del Buono, A., Terracciano, A. M., Monda, M. V., Castro, F., Guaglianone, A., Maccari, V., Corsi, L., Versari, G., Falivene, M. R., Boletto, N., Corsi, S., Marafetti, L., Vitacolonna, E., Capani, F., Caputo, L., Di Nisio, L., Simonetti, F., Boscolo Bariga, A., Ballarin, G., De Boni, S., Di Benedetto, S., Chiambretti, A. M., Di Vito, L., Pascuzzo, M. D., Urli, P., Rumi, P., Balzarini, B., Galli, P., Castellan, M., Giannetti, A., Russotti, C., De Blasi, A., Perna, A., Campanelli, C., Ranchelli, A., Biccheri, D., Dadi, G., Massa, L., Baldi, G. P., Sciacca, F., Costanzo, E., Spada, M., Paolini, G., Ziller, P., Portolan, F., Pasolini, G., Ghilardi, G., Fiorina, P., Grata, M. L., Capretti, L., Speroni, G., Fugazza, L., Massafra, C., Lovagnini Scher, A., Cimicchi, M. C., Percudani, C., Risolo, T., Saccò, P., Gidoni Guarnieri, G. L., Piccolo, D., Bravin, C., De Noni, E., Scarpel, M., Marcon, M., Giacon, F., Panebianco, G., Tadiotto, F., Da Tos, V., D'Ambrosio, M., Pellizzola, D., Zampini, M. A., Frezzati, E., Mari, E., Raminelli, E., Gaiti, D., Bosi, E. A., Chierici, G., Pilla, S., Copelli, M., Zanichelli, P., Bertelli, L., Caretta, P., Vezzani, V., Bodecchi, S., Longobucco, A., Di Lembo, S., Spotti, E., Carrai, E., Degli Innocenti, A., Manini, L., Persico, R., Rossi, C., Magro, G., Marelli, G., Vilei, V., Andrioli, M., Bellato, L., Fedeli, M., Merlini, A., Pinelli, G., Marin, G., Contin, M. L., Gallo, A., Parlato, P., Pecchielan, W., Jacovacci, J., Placentino, G., Richini, D., Molinari, S., Strazzeri, R., Fabbri, T., Di Bartolo, P., Garrapa, G., D'Incau, F., Lagomanzini, P., Conte, P., Todesco, F., Foglini, P., Pantanetti, P., Bedetta, C., Maricotti, R., Tomasi, F., Monesi, M., Graziani, R., Beretta, F., Penna, L., Guberti, A., Dazzi, D., Forte, E., Gasbarrone, A., Marrocco, T., Moschetta, R., Tuccinardi, F., De Meo, F., Coppola, A., Pirolozzi, P., Placitelli, E., Vallefuoco, R., Catone, B., Ceschia, S., Urban, M., Fabbri, F., Torresani, M., Crovetto, R., Battistini, M., Carosia, P., Viviani, G. L., Durante, A., Pais, F., Lilliu, V., Quieto, C., D'Ugo, E., Squadrone, M., Amenduni, T., Iovannisci, M. M., Della Penna, L., Potente, F., Delle Donne, T., Massa, C., Ulisse, M. A., De Berardinis, S., Guarnieri, I., Pace, S., Splendiani, M., Di Giuseppe, R., Brunato, B., Assaloni, R., Muraro, R., Loro, R., Bucciol, S., Lavacca, C., Rossi, M., Sabbatini, G., Quadri, F., Sambuco, L., Santacroce, C., Paola Caretta, D., Marino, C., Micheletti, A., Petrelli, A., Corda, A., Pisano, L., Guaita, G., Deias, C., Trevisan, G., Coletti, I., Iannarelli, R., De Luca, A., Minnucci, A., Antenucci, D., Di Florio, C., Angelicola, G., Bosco, A., Fresco, R., Di Marco, G., Ugolotti, D., Cadossi, T., Di Caro, P., Mazzocchetti, M., Buzzetti, R., Leto, G., Gnessi, C., Cipolloni, L., Foffi, C., Moretti, C., Venditti, C., Meniconi, R., Bertoli, S., Cosimi, S., Di Cianni, G., Turco, A., Richini, A., Marconi, S., Sannino, C., Lemmi, P., Giuntoli, S., Manfrè, N., Giannini, F., Di Carlo, A., Casadidio, I., Melandri, P., Maolo, G., Polenta, B., Piccinini, N., Vincenti, C., Pastore, N., Mega, P., Magurano, E., Cananiello, A., Francescutto, C. A., Brussa Toi, E., Gaspardo, G., Angeli, L., Ronchese, L., Sciangula, L., Ciucci, A., Contartese, A., Banfi, E., Castelli, E., Tatti, P., Bloise, D., Di Mauro, P., Masselli, L., Lo Presti, A., Scarpitta, A. M., Gambina, F., Venezia, A., Morea, R., Lagonigro, G., Copeta, G., Iannucci, V., Milano, V., Trupo, M., Lochmann, A., Marchetto, P. E., Incelli, G., De Paola, G., Steiger, M. M., Gamper, M. A., Breitenberger, S., Holzner, M., Frischmann, J., Lambiase, C., Di Vece, T., D'Aniello, M., Fezza, M., Giordano, C., Leo, F., Saitta, G., Cucinotta, D., Di Vieste, G., Pintaudi, B., Mancuso, T., Musacchio, N., Giancaterini, A., Pessina, L., Salis, G., Schivalocchi, F., Testori, G., Rampini, P. A., Cerutti, N., Morpugo, P. S., Cavaletto, M. L., Bonino, G., Morreale, F., Mariani, G., Ragonesi, P. D., Bollati, P., Colapinto, P., Bosi, E., Falqui, L., Bortolato, L., Cosma, A., Pistolato, P., Centenaro, B., Ceccato, A., Campobasso, G., Zaurino, F., Mazzotta, G., Manti, R., Da Ros, R., Carlucci, S., Narduzzi, L., Bortolotto, D., D'Acunto, L., Stanic, L., Volpi, A., Cospite, A. M., Manicardi, V., Michelini, M., Finardi, L., Borghi, F., Manicardi, E., Lombardi, S., Tommasi, C., Iaccarino, M., Cozza, S., Binotto, M., Marini, F., Mecenero, I., Massignani, S., Stecco, P., Urbani, E., Massariol, W., Parolin, R., Gatti, A., Bonavita, M., Creso, E., Giannettino, R., Gobbo, M., Iovine, C., Turco, A. A., Riccardi, G., Iazzetta, N., Giannattasio, C., Egione, O., Galdieri, S., Velotti, A., Azzolina, A., Annicelli, G., Sorrentino, T., Gaeta, I., Zenari, L., Bertolini, L., Sorgato, C., Grippaldi, F., Stroppiana, M., Popolizio, R., Carbone, N., Grasso, S., Abate, S., Gaggero, G. C., Strazzabosco, M., Brun, E., Carlesi, G. P., Garrone, S., Cicalò, A. M., Clausi, C., Cau, R., Manconi, A., Carboni, A., Angius, M. F., Pinna, A. A., Caria, S., Filigheddu, G. D., Tonolo, G., Carta, I., Calebich, S., Burlotti, C., Saglietti, G., Schellino, A., Madau, G., Cossu, M., Mulas, F., Zoccheddu, S., Balsanelli, M., Fetonti, M., Rotolo, A., Sambo, P., Secchi, E., Angotzi, M. A., Loddoni, S., Brundu, I., Careddu, F., Becciu, A., Gabriella Piras, G., Novara, F., Cipro, F., Torchio, G., Palumbo, P., Bianchi, A., Colucci, G., La Motta, G., Tiengo, A., Avogaro, A., Bruttomesso, D., Crepaldi, C., Fadini, G., Guarnieri, G., Lavagnini, M. T., Maran, A., Vedovato, M., De Kreutzenberg, V., Fedele, D., Lapolla, A., Sartore, G., Bax, G., Cardone, C., Dalfrà, M. G., Masin, M., Toniato, R., Piarulli, Francesco, Mattina, G., Fulantelli, M. A., Gioia, D., Conti, M., Ridola, G., D'Agati, F., Grossi, G., De Berardinis, F., Zavaroni, I., Dei Cas, A., Franzini, L., Usberti, E., Antonimi, M., Anelli, N., Poli, R., Ridolfi, V., Michela, M., Haddoub, S., Prampolini, G., Muoio, A., Filippi, D., Bucci, F., Tardio, S. M., Calderini, M. C., Magotti, M. G., Quarantelli, C., Vernazza, M. A., Carolfi, A., Saracca, R., Picchio, E., Del Sindaco, P., Spalluto, A., Maggiulli, L., Torreggiani, V., Rastelletti, S., Ugolini, C., Pucci, N., Magi, S., Muratori, S., La Penna, G., Consoli, A., Galeone, F., Magiar, A. V., Gherardini, V., Moretti, L., Bientinesi, M., Landi, L., Bernardi, A., Del Prato, S., Miccoli, R., Bianchi, C., Penno, G., Venditti, F., Anichini, R., De Bellis, A., Bruschi, T., Butelli, L., Gioffredi, M., Gori, R., Picciafuochi, R., Malagoli, R., Bernini, A., Gelisio, R., Zanon, M., Del Bianco, A., Bamiston, A., Signorato, M., Citro, G., Calabrese, M., Ianni, L., Lorenzetti, M., Marsocci, A., Guizzotti, S., Memoli, G., Cabasino, F., Farci, F., Atzori, A., Sanna, A., Ghiani, M., Siotto, I., Sedda, M., Manis, A., Loddo, C., Loddo, I., Seguro, P., Cuomo, A., Orlando, L., Olanda, G. B., Pucci, A., Massenzo, M., Sardu, C., Perrone, G., Corazziere, F., La Puzza, I., Tripodi, P. F., Riggio, S., Giampaolo, A., Mannino, D., Aleandri, A. R., Guidi, M. V., Battisti, B., Faraglia, M. R., Lilli, V., Leotta, S., Visalli, N., Gagliardi, A., Fontana, L., Altomare, M., Carletti, S., Abbruzzese, S., Chiaramonte, F., Giordano, R., Rossini, M., Migneco, G., Cappelloni, D., Urbani, A., Piergiovanni, F., Fava, D., Simonetta, A., Massimiani, F., Bulzomì, R., Giuliano, M., Pennafina, M. G., Di Perna, P., D'Accinni, M. P., Paolucci, D., D'Ubaldi, A., D'Angelo, M. T., Masaro, G., Pietrantoni, M., Fratini, M., La Rosa, R., Poggi, M., Piccirilli, F., Pisano, R., Saponara, C., Conforti, I., Penza, A., Scalpone, R., Lo Pinto, S., Iacovella, L., Caccamo, C., Sposito, S., Teodonio, C., Restuccia, M. G., Mirto, G., Girardello, R., Gennaro, R., De Moliner, L., Bettini, E., Mattuzzi, A., Speese, K., Frisinghelli, F., Locatelli, F., Nicoletti, M., Trojan, N., Centis, R., L Volsi, P., Levis, E., Zanette, G., Comba, G., Ballatore, L., Cattaneo, A., Aglialoro, A., Guido, R., Patrone, M., Zecchini, M., Vespasiani, G., Meloncelli, I., Clementi, L., Galetta, M., Marconi, V., Bordin, P., Perale, L., Vinci, C., Sira Zanon, M., Geretto, L., Toffolo, C., Furlan, M. G., Mazzanti, G., Vinci, M., Sica, V., Armeni, M., Derai, R., Ennas, O., Mamusa, S., Pisano, M. A., Carreras, L., Rauseo, A., Cervone, S., Leggieri, A., Pontonio, M., Sturaro, R., Quattrocchi, F., Molinaro, M., Trasatti, M., Ferretti, B., Labarile, G., Baule, G. M., Gentilini, A., Spanu, M. A., Fancellu, A., Bianco, P., Lione, L., Massazza, G., Bocchio, G., Bosco, E., Monachesi, M., Carta, G., Boschetti, M., Ceresola, E., Venier, E., Calcaterra, F., Cataldi, F., Miola, M., Manfrini, S., Lai, A., Locci, B., Putzu, D., Tanganelli, I., Leonini, M., Egger, K., Marchiotto, W., Vincis, L., Orlandini, V., Pilloni, C., Farci, R., Pelligra, I., Renier, G., Mameli, M., Pala, A., Devigus, E., Fumagalli, I., Lalli, C., Leandri, M., Agliani, M., De Pascalis, L., Malci, F., De Ciocchis, A., Diodati, M. B., Macerola, B., Davì, S., Caccavale, A., Brocato, L., Pognant Gros, M., Borla, S., Lattanzi, E., Piersanti, C., Piersanti, A., Spinelli, I., Tuzzoli, L., Tulini, V., Quaranta, G., Iorio, V., Tirabovi, M., De Terlizi, Candia, Massarelli, M. G., Venturi, S., Travaglini, A., Draghi, P., Pomante, P., Richiardi, L., Clerico, A., Bruno, A., Cavallo Perin, P., Ghigo, E., Porta, M., Scuntero, P., Arcari, R., Bertaina, S., Bo, S., Broglio, F., Bruno, G., Degiovanni, M., Fornengo, P., Grassi, G., Inglese, V., Maccario, M., Maghenzani, G., Marena, S., Martina, V., Passera, P., Ruiu, G., Tagliabue, M., Zanone, M., Monge, M., Boffano, G. M., Macrì, K., Maio, P., Ozzello, A., Pergolizzi, E., Gaia, D., Gennari, P., Micali, G., Rossetto, E., Dalmazzo, C., Oreglia, M., Stefani, T., Dossena, C., Paglia, P., Bosoni, S., Romanelli, T., Inchiostro, S., Dauriz, M., Bossi, C. A., Meregalli, G., Balini, A., Berzi, D., Filippini, B., Crotto, G., Paccagnella, A., Orrasch, M., Sambataro, M., Citro, T., Kiwanuka, E., Bagolin, E., Almoto, B., Macchia, A., Branca, M. T., Filesi, M., Candido, R., Caroli, E., Manca, E., Petrucco, A., Tommasi, E., Jagodnik, G., Baskar, B., Daris, N., Dal Col, P., Pellegrini, M. A., Tonutti, L., Venturini, G., Andreani, M., Turchi, F., Fedrighelli, F., Martinelli, G., Rongioletti, R., Candidi, M., Pais, M., Moro, E., Cervellino, F., Sinisi, R., Zampino, A., Mingardi, R., Lora, L., Reitano, R., Stocchiero, C., Simoncini, M., Mesturino, C. A., Zen, F., Di Pietro, S., Scoponi, C., Tilaro, L., Pelliccioni, S., Slongo, R., Vita, E., Garofalo, A., Vitale, F., Campanella, B., Mastrilli, V., Borrelli, T., D'Avino, A., Perbellini, A., Mirijello, Antonio, Viazzi, Francesca, Fioretto, Paola, Giorda, Carlo, Ceriello, Antonio, Russo, Giuspina T, Guida, Pietro, Pontremoli, Roberto, and De Cosmo, Salvatore, Giordano, Carla
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Adult ,Male ,Nephrology ,medicine.medical_specialty ,endocrine system diseases ,Renal function ,030209 endocrinology & metabolism ,030204 cardiovascular system & hematology ,lcsh:RC870-923 ,Kidney ,urologic and male genital diseases ,GFR ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Diabetes mellitus ,medicine ,Humans ,Albuminuria ,Diabetic kidney disease ,Type 1 diabetes ,urogenital system ,business.industry ,Incidence (epidemiology) ,Middle Aged ,lcsh:Diseases of the genitourinary system. Urology ,medicine.disease ,female genital diseases and pregnancy complications ,Albuminuria, Diabetic kidney disease, GFR, Nephrology ,Diabetes Mellitus, Type 1 ,medicine.anatomical_structure ,Italy ,Disease Progression ,Female ,medicine.symptom ,business ,Research Article ,Follow-Up Studies ,Glomerular Filtration Rate ,Kidney disease - Abstract
Background Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage ≥3 CKD (eGFR 30% from baseline was evaluated. Results The mean estimated GFR was 98 ± 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions Albuminuria and eGFR reduction represent independent risk factors for incident stage ≥3 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening. Electronic supplementary material The online version of this article (10.1186/s12882-018-1136-6) contains supplementary material, which is available to authorized users.
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- 2018
8. Thrombophilia and Transient Risk Factors for Venous Thromboembolism in Women with Distal Deep Vein Thrombosis
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Cozza, S., primary, Mercier, G., additional, Schved, J.F., additional, and Biron-Andréani, C., additional
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- 2007
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9. F175S Change and a Novel Polymorphism in Presenilin-1 Gene in Late-Onset Familial Alzheimer’s Disease
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Colacicco, A.M., primary, Panza, F., additional, Basile, A.M., additional, Solfrizzi, V., additional, Capurso, C., additional, D’Introno, A., additional, Torres, F., additional, Capurso, S., additional, Cozza, S., additional, Flora, R., additional, and Capurso, A., additional
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- 2002
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10. Knowledge of prophylaxis treatment therapy among HIV-positive prisoners
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Stephens, T. T., primary, Braithwaite, R., additional, and Cozza, S., additional
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- 1999
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11. CAMCE: An Environment to Support Multimedia Courseware Projects
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Barrese, R.M., primary, Calabrò, G., additional, Cozza, S., additional, Gallo, T., additional, and Tisato, F., additional
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- 1992
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12. An object based environment for multimedia courseware engineering.
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Calabro, G., Cozza, S., Gallo, T., and Tisato, D.
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- 1992
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13. Transsexual orientation in HIV risk behaviours in an adult male prison.
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Stephens, Torrance, Cozza, Scott, Braithwaite, Ronald L, Stephens, T, Cozza, S, and Braithwaite, R L
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AIDS ,HIV infections ,TRANSSEXUALS ,SEXUAL orientation ,MALES ,PRISONS ,HIV infections & psychology ,RISK-taking behavior ,SOCIAL participation ,HUMAN sexuality ,PRISONERS ,PSYCHOLOGICAL tests ,PSYCHOSOCIAL factors - Abstract
The present study examined the consequences of being a self-reported transsexual male and HIV risk behaviours in a state penal system. The specific research question was whether or not sexual orientation of inmates influences the level to which they evidence HIV risk behaviours. A total of 153 participants volunteered to participate in the study of which 31 described themselves as being transsexual. Based on risk ratios and using transsexual inmates (TIs) as the reference group, they were 13.7 times more likely to have a main sex partner while in prison [95% CI=5.28, 35.58]. Moreover, TIs were 5.8 times more likely than non-transsexual inmates (NTIs) to report having more than one sex partner while in prison [95% CI=2.18, 15.54]. It is obvious from these findings that TIs require more preventive support than their NTI confederates. In addition to TIs being protected from assault and battery by NTIs, they need social support and carefully developed preventive informational materials. [ABSTRACT FROM AUTHOR]
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- 1999
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14. CAMCE: An Environment to Support Multimedia Courseware Projects.
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Barrese, R.M., Calabrò, G., Cozza, S., Gallo, T., and Tisato, F.
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This paper presents the major results of a research done in the framework of the CAMCE (Computer‐Aided Multimedia Courseware Engineering) project funded within the DELTA (Developing European Learning through Technological Advance) European Community Programme. The project aims to design and prototype a distributed authoring environment supporting the multimedia courseware development process. The first project activity was the definition of a methodology describing in detail a systematic approach to multimedia courseware development. The methodology aim is to provide requirements for the functional specifications of the CAMCE authoring environment. Integration among data and tools is considered a major requirement. Representing data and tools as a network of (multi‐represented) objects, on which different views (environments) are defined, is the basic approach adopted in this project. [ABSTRACT FROM PUBLISHER]
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- 1992
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15. Enhancing ASP by functions: Decidable classes and implementation techniques
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Francesco Calimeri, Cozza, S., Ianni, G., and Leone, N.
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General Medicine - Abstract
This paper summarizes our line of research about the introduction of function symbols (functions) in Answer Set Programming (ASP) – a powerful language for knowledge representation and reasoning. The undecidability of reasoning on ASP with functions, implied that functions were subject to severe restrictions or disallowed at all, drastically limiting ASP applicability. We overcame most of the technical difficulties preventing this introduction, and we singled out a highly expressive class of programs with functions (FG-programs), allowing the (possibly recursive) use of function terms in the full ASP language with disjunction and negation. Reasoning on FG-programs is decidable, and they can express any computable function (causing membership in this class to be semi-decidable). We singled out also FD-programs, a subset of FG-programs which are effectively recognizable, while keeping the computability of reasoning. We implemented all results into the DLV system, thus obtaining an ASP system allowing to encode any computable function in a rich and fully declarative KRR language, ensuring termination on every FG program. Finally, we singled out the class of DFRP programs, where decidability of reasoning is guaranteed and Prolog-like functions are allowed.
16. Enhanced wavelength conversion based on SOA XGM and XPM
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Lucia Marazzi, Parolari, P., Boffi, P., Cozza, S., and Martinelli, M.
17. Color Doppler US to differentiate benign from malignant lymphatic enlargement,Ruolo del color Doppler nella diagnosi differenziale delle adenopatie benigne e maligne
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Ferrari, F. S., Cozza, S., Guazzi, G., Della Sala, L., Leoncini, L., STEFANO LAZZI, and Stefani, P.
18. [Color Doppler echography in the study of obstruction-related lung collapse]
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Fs, Ferrari, Cozza S, Baldini R, Boni S, FRANCESCO MARIA DRUDI, Stefani P, and Passariello R
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Adult ,Male ,Pulmonary Atelectasis ,Bronchial Neoplasms ,Humans ,Bronchi ,Female ,Middle Aged ,Ultrasonography, Doppler, Color ,Lung ,Aged - Abstract
The typical US pattern of obstructive atelectasis consists in a triangular hypoechoic area with anechoic bands inside related to fluid-filled bronchial structures--the US fluid bronchogram sign. According to some authors, this US sign within a chest mass indicates pulmonary parenchyma disease. Furthermore, it suggests the diagnosis of lung collapse. Sixty-one patients with obstructive atelectasis confirmed with conventional radiography, conventional and computed tomography, and bronchoscopy were submitted to B-mode and color-Doppler US to assess the importance of the US fluid bronchogram sign in obstructive pulmonary atelectasis. In this condition, B-mode US showed tubular anechoic bands in 59/61 patients. Power Doppler venous sampling showed a Doppler spectrum with marked phase oscillations. Arterial sampling showed a Doppler spectrum with high distal impedance-with poor or totally absent diastolic component. To conclude, in the atelectasis area, B-mode US showed in 96% of patients some anechoic bands with no apparent pulsatility. Color-Doppler showed color flow in 100% of cases, which confirmed the vascular nature of the masses. Thus, the US fluid bronchogram, which is frequently described in the literature, was never observed in our series. Power Doppler spectral flow analysis can be useful in the diagnosis of obstructive atelectasis because it depicts the hemodynamics of atelectasis parenchyma. Indeed, the arterial spectrum with high distal resistance is consistent with the effects of hypoxia on intra-atelectatic blood vessels. Further research is necessary to assess the role of color-Doppler US in the hemodynamic study of intra-atelectatic vessels. However, our preliminary results open new perspectives for the acquisition of physiopathologic data on abnormal blood flow in obstructive atelectasis.
19. [Role of Doppler color in the differential diagnosis of benign and malignant adenopathies]
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Leoncini, Lorenzo, Cozza, S., Guazzi, Giancarlo, Della Sala, L., Leoncini, L., STEFANO LAZZI, and Stefani, Paolo
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Adult ,Aged, 80 and over ,Male ,Adolescent ,Aged ,Diagnosis, Differential ,Female ,Humans ,Lymphatic Diseases ,Lymphatic Metastasis ,Middle Aged ,Ultrasonography, Doppler, Color ,Doppler ,Color ,Diagnosis ,Differential ,80 and over ,Ultrasonography - Abstract
The diagnosis of enlarged lymph nodes is of the utmost importance especially in the treatment planning of cancer patients. US yields such morphological findings as node size, longitudinal/transverse diameter ratio, hilum visibility and cortical thickness, which however do not permit the differential diagnosis of benign from malignant forms. Some authors tried to distinguish inflammatory enlargement from metastatic forms on the basis of color Doppler findings, with conflicting and questionable results. We investigated the potentials of color Doppler US in the differential diagnosis of benign and malignant lymph node enlargement using morphological data and flow measurements in lymphatic hilum vessels. The palpable superficial lymph nodes of 70 patients were studied with color Doppler with a linear probe (7.5-10 MHz) equipped for Doppler flow measurements. The largest lymph node was studied in multiple enlargement. The final diagnosis was made with US-guided cytology and/or excisional biopsy. The venous hilar vessels were depicted with color Doppler US in 44/45 patients with lymphadenitis and only in 1/17 patients with metastatic enlargement. Spectral Doppler exams of the hilar arteries showed flows with a wide telediastolic component in lymphadenitis (relative RI:0.58), while flow was rapid and with poor telediastolic component (relative RI:0.84) in metastatic enlargement. Average RI was 0.62 in Hodgkin's lymphomas and 0.71 in all the other lesions. We conclude that the distortion and compression of the main hilar vessels in metastatic lymph node enlargement often prevents color Doppler depiction of venous vessels. Moreover, the compression and distortion of the intranodal capillary network (the "mass" effect) often results in increased RI, as detected with power Doppler in the lymphatic hilum. Even though color Doppler US studies of the hemodynamic changes in the hilar vessels need further validation in larger series of cases, our preliminary results suggest interesting potentials in distinguishing inflammatory from metastatic enlargement, which differentiation remains nevertheless difficult especially in Hodgkin's lymphoma.
20. Risperidone may help schizophrenic teens.
- Author
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Cozza, S. and Edison, D.
- Subjects
- *
SCHIZOPHRENIA in adolescence , *THERAPEUTICS - Abstract
Reports on the results of two case studies which show the potential benefit of risperidone as treatment for adolescents with schizophrenia. Sensitivity of adolescents to risperidone; Treatment procedures used; Decrease in both positive and negative psychotic symptoms.
- Published
- 1995
21. A Voxel-Based Assessment of Noise Properties in Computed Tomography Imaging with the ASiR-V and ASiR Iterative Reconstruction Algorithms
- Author
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A. C. Traino, Stefano Diciotti, Marco Giannelli, Chiara Marzi, Patrizio Barca, Daniela Marfisi, Sabino Cozza, Barca P., Marfisi D., Marzi C., Cozza S., Diciotti S., Traino A.C., and Giannelli M.
- Subjects
Technology ,QH301-705.5 ,Noise reduction ,media_common.quotation_subject ,QC1-999 ,noise level ,Computed tomography ,ASiR-V ,Iterative reconstruction ,computer.software_genre ,Imaging phantom ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Voxel ,medicine ,Contrast (vision) ,General Materials Science ,Biology (General) ,Instrumentation ,QD1-999 ,Mathematics ,media_common ,Fluid Flow and Transfer Processes ,iterative reconstruction algorithms ,medicine.diagnostic_test ,Radon transform ,Process Chemistry and Technology ,Physics ,General Engineering ,computed tomography ,Iterative reconstruction algorithm ,noise spatial uniformity ,Engineering (General). Civil engineering (General) ,Computer Science Applications ,Noise ,Chemistry ,ASiR ,030220 oncology & carcinogenesis ,TA1-2040 ,Algorithm ,computer - Abstract
Given the inherent characteristics of nonlinearity and nonstationarity of iterative reconstruction algorithms in computed tomography (CT) imaging, this study aimed to perform, for the first time, a voxel-based characterization of noise properties in CT imaging with the ASiR-V and ASiR algorithms as compared with conventional filtered back projection (FBP). Multiple repeated scans of the Catphan-504 phantom were carried out. CT images were reconstructed using FBP and ASiR/ASiR-V with different blending levels of reconstruction (20%, 40%, 60%, 80%, 100%). Noise maps and their nonuniformity index (NUI) were obtained according to the approach proposed by the report of AAPM TG-233. For the homogeneous CTP486 module, ASiR-V/ASiR allowed a noise reduction of up to 63.7%/52.9% relative to FBP. While the noise reduction values of ASiR-V-/ASiR-reconstructed images ranged up to 33.8%/39.9% and 31.2%/35.5% for air and Teflon contrast objects, respectively, these values were approximately 60%/50% for other contrast objects (PMP, LDPE, polystyrene, acrylic, Delrin). Moreover, for all contrast objects but air and Teflon, ASiR-V showed a greater noise reduction potential than ASiR when the blending level was ≥40%. While noise maps of the homogenous CTP486 module showed only a slight spatial variation of noise (NUI <, 5.2%) for all reconstruction algorithms, the NUI values of iterative-reconstructed images of the nonhomogeneous CTP404 module increased nonlinearly with blending level and were 19%/15% and 6.7% for pure ASiR-V/ASiR and FBP, respectively. Overall, these results confirm the potential of ASiR-V and ASiR in reducing noise as compared with conventional FBP, suggesting, however, that the use of pure ASiR-V or ASiR might be suboptimal for specific clinical applications.
- Published
- 2021
22. Therapeutic alliance building during the child psychiatric intake: does VTC make a difference?
- Author
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Penska K, Michael R, Messer SC, Smith R, Black NB, Cozza S, Penska, Keith, Michael, Robin, Messer, Stephen C, Smith, Ryan, Black, Nancy B, and Cozza, Stephen
- Abstract
This study examined potential changes in perceptions of therapeutic ("working") alliance during a child's initial diagnostic interview from the parent's perspective. The major study objective was to determine whether parental perceptions of alliance vary by group (video teleconferencing [VTC], face-to-face [FTF]) over time (Pre, Post intake). It was predicted that parental alliance would be more favorable after an FTF encounter relative to a VTC intervention. Participants were recruited and enrolled in two study cohorts between August 2000 and October 2005. Parents completed the Parental Perceptions of Alliance Questionnaire (PPAQ) immediately before (pre-PPAQ) and after (post-PPAQ) their interview. Analysis of variance (ANOVA) tests showed that the mean PPAQ scores of FTF groups being higher than that of VTC groups (controlling for time) was statistically significant, F (1,144) = 4.14, p = 0.04. However, upon further analysis, the interaction effect was not significant, F (1,144) = 1.20, p = 0.28. Findings from the current exploratory study suggest that, at least following an intake child psychiatric examination, parents' perceptions of therapeutic alliance are stronger than they were before intake for those conducted in an FTF format as well as through VTC. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
23. Child neglect in Army families: a public health perspective.
- Author
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Fullerton CS, McCarroll JE, Feerick M, McKibben J, Cozza S, Ursano RJ, Child Neglect Workgroup, Fullerton, Carol S, McCarroll, James E, Feerick, Margaret, McKibben, Jodi, Cozza, Stephen, and Ursano, Robert J
- Abstract
Military families include 2.9 million people, with approximately 40% of all service members having at least one child. Rates of child neglect in this population have increased in recent years, but little is known about the characteristics of the neglect. To better identify targets for intervention, it is necessary that we refine our understanding of child neglect in the military. In this review, we examine definitions of child neglect and the specific definitions used by the U.S. Army. We identify domains of neglect and caregiver behaviors and affiliated. We suggest that this approach can inform prevention efforts within the Institute of Medicine's framework for preventive interventions. Understanding risk and protective factors in the military family are important to interventions for child neglect in military families. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
24. Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib
- Author
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Marina Ferrarini, Silvia Nerini-Molteni, Federico Caligaris-Cappio, Roberto Sitia, Sara Cozza, NERINI MOLTENI, S, Ferrarini, M, Cozza, S, CALIGARIS CAPPIO, F, and Sitia, Roberto
- Subjects
Antineoplastic Agents ,Biology ,Antioxidants ,Bortezomib ,chemistry.chemical_compound ,Tumor Cells, Cultured ,medicine ,Homeostasis ,Humans ,Protease Inhibitors ,Buthionine sulfoximine ,Multiple myeloma ,Cell Death ,Dose-Response Relationship, Drug ,GCLM ,ATF4 ,Hematology ,Glutathione ,medicine.disease ,Activating Transcription Factor 4 ,Boronic Acids ,Acetylcysteine ,Neoplasm Proteins ,chemistry ,Proteasome ,Pyrazines ,Cancer research ,Proteasome inhibitor ,Drug Screening Assays, Antitumor ,Multiple Myeloma ,Oxidation-Reduction ,Transcription Factor CHOP ,medicine.drug - Abstract
The use of proteasome inhibitors have been a major advance in the treatment of multiple myeloma (MM), but their mechanisms of action remain largely unclear. A better understanding of the cellular events downstream of proteasome inhibition is essential to improve the response and identify new combination therapies for MM and other malignancies. This study analysed the relationships between redox homeostasis and bortezomib treatment in MM cells. Our data showed that decreasing intracellular glutathione through buthionine sulfoximine treatment strongly enhances bortezomib toxicity, whilst antioxidants protect MM cells from bortezomib-mediated cell death. Bortezomib treatment decreases intracellular glutathione both in MM cell lines and in malignant plasma cells obtained from MM patients. Glutamate-cysteine ligase (GCLM) and haem-oxygenase-1 (HMOX1), two genes involved in the Nrf-2-mediated antioxidant response, as well as two eIF2alpha-downstream transcription factors, activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP), are upregulated, indicating that redox-related adaptive responses are initiated in bortezomib-treated MM cells. These findings demonstrate tight links between sensitivity to proteasome inhibition and redox homeostasis in MM cells and have potential implications for treatment.
- Published
- 2008
25. Near-infrared camera in polycrystalline germanium integrated on complementary-metal-oxide semiconductor electronics
- Author
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Stefano Cozza, F. DeNotaristefani, Lorenzo Colace, Valentino Orsolini Cencelli, Gianlorenzo Masini, Gaetano Assanto, Colace, L, Masini, G, Cozza, S, Assanto, Gaetano, DE NOTARISTEFANI, Francesco, Cencelli, V., Colace, Lorenzo, Denotaristefani, F, Lorenzo, Colace, Gianlorenzo, Masini, Stefano, Cozza, and Valentino, Cencelli
- Subjects
Materials science ,Physics and Astronomy (miscellaneous) ,Silicon ,Physics::Instrumentation and Detectors ,business.industry ,Photodetector ,chemistry.chemical_element ,Germanium ,chemistry ,CMOS ,Optoelectronics ,Electronics ,Image sensor ,business ,Dark current ,Electronic circuit - Abstract
The authors demonstrate a two-dimensional array of Si-integrated photodetectors equipped with readout electronics and operating in the near infrared. The chip is realized in polycrystalline Ge on a silicon complementary metal oxide semiconductor circuitry and includes 512 pixels, 64 analog to digital converters, dark current cancellation, and test/calibration facilities. They describe its design, fabrication, characterization, and operation as a near-infrared image sensor.
- Published
- 2007
26. Transcranial ultrasonography imaging of a suprasellar meningioma: A case description and technical notes.
- Author
-
Meini S, Rossi C, Venturini L, Mura M, Bracalente I, Andreini R, Sgura A, and Cozza S
- Abstract
Background: Computed tomography (CT) and magnetic resonance (MR) represent the gold standard for evaluating intracranial tumours, such as meningiomas; most meningiomas can be managed by surveillance and clinical follow-up, therefore, the ideal technology should be cheap, non-invasive, safe and able to reduce radiation exposure. Transcranial colour-coded duplex sonography (TCCS) can detect space-occupying lesions, but its full potential for clinical practice is still unexpressed., Aims and Methods: We describe the ability of TCCS to directly and accurately image, in a 77-year-old woman hospitalised for septic shock and coma, a suprasellar meningioma with a spatial resolution very similar to CT., Results: The meningioma was clearly visualised as a roundish mass, with well-defined borders, heterogeneously hyperechogenic compared with the surrounding brain structures; multiple intralesional calcifications were detectable as highly echogenic spots. Latero-lateral and antero-posterior diameters were well measurable., Discussion: TCCS should not be considered as an alternative to CT and MR imaging, but it might have a complementary role, useful for use at the bedside in uncooperative or non-transportable patients and for follow-up, when an adequate acoustic window is guaranteed. Neurologists and neuroradiologists should further explore the full potential of this technology., Competing Interests: None to declare., (© 2022 Australasian Society for Ultrasound in Medicine.)
- Published
- 2022
- Full Text
- View/download PDF
27. Detection of a pituitary macroadenoma with transcranial ultrasonography: Principles and potential clinical applications.
- Author
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Meini S, Andreini R, and Cozza S
- Subjects
- Adult, Brain, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Ultrasonography, Ultrasonography, Doppler, Color methods, Ultrasonography, Doppler, Transcranial methods
- Abstract
Transcranial color-coded duplex sonography (TCCS) allows to study intracranial vessels through the intact skull, but the visualization of normal and pathologic brain structures in adults is often suboptimal due to inadequate acoustic window. The full potential of TCCS for clinical practice remains unfulfilled. Here, we describe the ability of TCCS to detect a non-functioning pituitary macroadenoma in a 58-year-old man affected by headache. The macroadenoma was visualized as a roundish, well-defined mass, mildly hyperechogenic compared to the hypoechogenic mesencephalic brainstem but mainly hypoechogenic compared to the surrounding intracranial structures. Intracranial vessels represented useful landmarks. Using tissue harmonic imaging mode, the borders of the macroadenoma were visualized more clearly. Macroadenoma characteristics were confirmed by magnetic resonance imaging. Neurosonologists should be aware of the possibility to incidentally find, during routinary TCCS, pituitary macroadenomas or other brain tumors (as incidentalomas), worthy to be recognized and referred for further investigations., (© 2022 Wiley Periodicals LLC.)
- Published
- 2022
- Full Text
- View/download PDF
28. Progression from Vegetative to Minimally Conscious State Is Associated with Changes in Brain Neural Response to Passive Tasks: A Longitudinal Single-Case Functional MRI Study.
- Author
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Tomaiuolo F, Cecchetti L, Gibson RM, Logi F, Owen AM, Malasoma F, Cozza S, Pietrini P, and Ricciardi E
- Subjects
- Adult, Brain diagnostic imaging, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Male, Persistent Vegetative State diagnostic imaging, Young Adult, Brain physiopathology, Persistent Vegetative State physiopathology, Speech Perception physiology
- Abstract
Objectives: Functional magnetic resonance imaging (fMRI) may be adopted as a complementary tool for bedside observation in the disorders of consciousness (DOC). However, the diagnostic value of this technique is still debated because of the lack of accuracy in determining levels of consciousness within a single patient. Recently, Giacino and colleagues (2014) hypothesized that a longitudinal fMRI evaluation may provide a more informative assessment in the detection of residual awareness. The aim of this study was to measure the correspondence between clinically defined level of awareness and neural responses within a single DOC patient., Methods: We used a follow-up fMRI design in combination with a passive speech-processing task. Patient's consciousness was measured through time by using the Coma Recovery Scale., Results: The patient progressed from a vegetative state (VS) to a minimally conscious state (MCS). Patient's task-related neural responses mirrored the clinical change from a VS to an MCS. Specifically, while in an MCS, but not a VS, the patient showed a selective recruitment of the left angular gyrus when he listened to a native speech narrative, as compared to the reverse presentation of the same stimulus. Furthermore, the patient showed an increased response in the language-related brain network and a greater deactivation in the default mode network following his progression to an MCS., Conclusions: Our findings indicate that longitudinal assessment of brain responses to passive stimuli can contribute to the definition of the clinical status in individual patients with DOC and represents an adequate counterpart of the bedside assessment during the diagnostic decision-making process. (JINS, 2016, 22, 620-630).
- Published
- 2016
- Full Text
- View/download PDF
29. Comparative Evaluation of Two PCR-Based Methods for Detection of Methicillin-Resistant Staphylococcus aureus (MRSA): Xpert MRSA Gen 3 and BD-Max MRSA XT.
- Author
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Lepainteur M, Delattre S, Cozza S, Lawrence C, Roux AL, and Rottman M
- Subjects
- Humans, Nasal Cavity microbiology, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity, Staphylococcal Infections microbiology, Methicillin-Resistant Staphylococcus aureus genetics, Molecular Diagnostic Techniques methods, Polymerase Chain Reaction methods, Staphylococcal Infections diagnosis
- Abstract
We compared two walk-away molecular diagnostic assays, the GeneXpert MRSA Gen 3 assay and the BD-Max MRSA XT assay. A total of 119 prospective swabs and 36 culture-positive samples were tested. Xpert MRSA Gen 3 had sensitivity of 95.7% and specificity of 100% versus 87.5% and 97.1% for BD-Max. The difference in agreement with the enriched culture results was significantly in favor of the Xpert assay (P < 0.02, McNemar nonparametric text)., (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
- Published
- 2015
- Full Text
- View/download PDF
30. Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation.
- Author
-
Wall CE, Cozza S, Riquelme CA, McCombie WR, Heimiller JK, Marr TG, and Leinwand LA
- Subjects
- Adaptation, Physiological physiology, Animals, Base Pairing genetics, Gene Expression Regulation, Humans, Hypertrophy, Molecular Sequence Annotation, Molecular Sequence Data, Myanmar, Myocardium metabolism, Myocardium pathology, Postprandial Period genetics, Postprandial Period physiology, RNA, Messenger genetics, RNA, Messenger metabolism, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid, Signal Transduction genetics, Time Factors, Adaptation, Physiological genetics, Boidae genetics, Boidae physiology, Fasting physiology, Feeding Behavior physiology, Gene Expression Profiling methods, Heart physiology
- Abstract
The infrequently feeding Burmese python (Python molurus) experiences significant and rapid postprandial cardiac hypertrophy followed by regression as digestion is completed. To begin to explore the molecular mechanisms of this response, we have sequenced and assembled the fasted and postfed Burmese python heart transcriptomes with Illumina technology using the chicken (Gallus gallus) genome as a reference. In addition, we have used RNA-seq analysis to identify differences in the expression of biological processes and signaling pathways between fasted, 1 day postfed (DPF), and 3 DPF hearts. Out of a combined transcriptome of ∼2,800 mRNAs, 464 genes were differentially expressed. Genes showing differential expression at 1 DPF compared with fasted were enriched for biological processes involved in metabolism and energetics, while genes showing differential expression at 3 DPF compared with fasted were enriched for processes involved in biogenesis, structural remodeling, and organization. Moreover, we present evidence for the activation of physiological and not pathological signaling pathways in this rapid, novel model of cardiac growth in pythons. Together, our data provide the first comprehensive gene expression profile for a reptile heart.
- Published
- 2011
- Full Text
- View/download PDF
31. Selective visual neglect in right brain damaged patients with splenial interhemispheric disconnection.
- Author
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Tomaiuolo F, Voci L, Bresci M, Cozza S, Posteraro F, Oliva M, and Doricchi F
- Subjects
- Aged, Aged, 80 and over, Brain Mapping, Corpus Callosum pathology, Corpus Callosum physiopathology, Female, Frontal Lobe pathology, Humans, Male, Middle Cerebral Artery pathology, Neuropsychological Tests, Parietal Lobe pathology, Attention physiology, Brain Injuries complications, Functional Laterality physiology, Perceptual Disorders etiology, Space Perception physiology
- Abstract
Left unilateral neglect is frequently reported after right hemispheric lesions of the middle cerebral artery (MCA) damaging the parietal-frontal cortical-subcortical network subserving space representation and awareness. However, accumulating evidence shows that neglect can also follow lesions of the posterior cerebral artery (PCA) that do not directly affect this parietal-frontal network. Surgical studies in the monkeys have demonstrated that complete callosal resection combined with lesion of the right optic tract entirely deprives the right hemisphere of visual inputs from the left hemispace provoking severe left unilateral neglect. Here, through the detailed study of two patients we show, for the first time, that PCA lesions selectively affecting the splenium of the corpus callosum and the adjacent right primary visual cortex provoke severe neglect selectively restricted to the visual domain. No trace of personal, motor or representational-imagery neglect was found. Also at variance with previous case studies in which neglect followed lesion of the trunk or the genu of the corpus callosum, no restriction of neglect to tasks performed with the right hand, no left hemispatial limb akinesia, no tactile extinction for the left hand and no tactile anomia for stimuli explored with the left hand were observed. These findings demonstrate that brain lesions depriving intact parietal and frontal attentional areas from specific sensory inputs can yield spatial neglect limited to specific sensory modalities or sectors of space.
- Published
- 2010
- Full Text
- View/download PDF
32. Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib.
- Author
-
Nerini-Molteni S, Ferrarini M, Cozza S, Caligaris-Cappio F, and Sitia R
- Subjects
- Acetylcysteine pharmacology, Activating Transcription Factor 4 metabolism, Antioxidants pharmacology, Boronic Acids antagonists & inhibitors, Bortezomib, Cell Death drug effects, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Glutathione metabolism, Homeostasis drug effects, Humans, Multiple Myeloma metabolism, Neoplasm Proteins metabolism, Oxidation-Reduction drug effects, Protease Inhibitors pharmacology, Pyrazines antagonists & inhibitors, Transcription Factor CHOP metabolism, Tumor Cells, Cultured, Antineoplastic Agents pharmacology, Boronic Acids pharmacology, Multiple Myeloma pathology, Pyrazines pharmacology
- Abstract
The use of proteasome inhibitors have been a major advance in the treatment of multiple myeloma (MM), but their mechanisms of action remain largely unclear. A better understanding of the cellular events downstream of proteasome inhibition is essential to improve the response and identify new combination therapies for MM and other malignancies. This study analysed the relationships between redox homeostasis and bortezomib treatment in MM cells. Our data showed that decreasing intracellular glutathione through buthionine sulfoximine treatment strongly enhances bortezomib toxicity, whilst antioxidants protect MM cells from bortezomib-mediated cell death. Bortezomib treatment decreases intracellular glutathione both in MM cell lines and in malignant plasma cells obtained from MM patients. Glutamate-cysteine ligase (GCLM) and haem-oxygenase-1 (HMOX1), two genes involved in the Nrf-2-mediated antioxidant response, as well as two eIF2alpha-downstream transcription factors, activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP), are upregulated, indicating that redox-related adaptive responses are initiated in bortezomib-treated MM cells. These findings demonstrate tight links between sensitivity to proteasome inhibition and redox homeostasis in MM cells and have potential implications for treatment.
- Published
- 2008
- Full Text
- View/download PDF
33. Thrombophilia and transient risk factors for venous thromboembolism in women with distal deep vein thrombosis.
- Author
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Cozza S, Mercier G, Schved JF, and Biron-Andréani C
- Subjects
- Adult, Female, Humans, Risk Factors, Young Adult, Thrombophilia complications, Venous Thromboembolism etiology, Venous Thrombosis complications
- Published
- 2008
- Full Text
- View/download PDF
34. Psychiatric interventions with returning soldiers at Walter Reed.
- Author
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Wain H, Bradley J, Nam T, Waldrep D, and Cozza S
- Subjects
- Combat Disorders psychology, Continuity of Patient Care, Hospitalization, Hospitals, General, Humans, Psychiatric Department, Hospital, Referral and Consultation, Stress Disorders, Post-Traumatic etiology, United States, Military Personnel psychology, Stress Disorders, Post-Traumatic rehabilitation
- Abstract
War is a malefic force and results in many psychiatric and medical casualties. Psychiatry's involvement with soldiers experiencing psychological stress resulting from combat experience has been reported for many years (Zajtchuk, 1995). It has been demonstrated that a myriad of diagnosis to include depression, anxiety, somatoform, adjustment disorders and psychotic behaviors also emerge (Wain et al., 1996, 2005a). Nearly all survivors exposed to traumatic events briefly exhibit one or more stress related symptoms (Morgan et al., 2003). In many instances these symptoms dissipate within a reasonable amount of time. However, symptoms persisting for a prolonged period following a traumatic event increase the probability of developing stress-related psychiatric disorders.
- Published
- 2005
- Full Text
- View/download PDF
35. History of prior TB infection and HIV/AIDS risk behaviours among a sample of male inmates in the USA.
- Author
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Stephens TT, Braithwaite R, Cozza S, Robillard A, and Arriola KJ
- Subjects
- Adult, Demography, Female, HIV Infections complications, Health Surveys, Humans, Male, Prisons, Risk Factors, Sexual Behavior, Substance Abuse, Intravenous, Tuberculosis, Pulmonary complications, United States, HIV Infections transmission, Prisoners, Risk-Taking, Tuberculosis, Pulmonary transmission
- Abstract
This study looked at inmates' self-reported data on prior treatment for tuberculosis (TB) and HIV/AIDS risk among a sample of inmates in a medium security prison. Contingency tables were used and risk ratios were computed to provide an estimate of relative risk for inmates with a history of being treated for TB in opposition to inmates without a history of being treated for TB. Findings suggest that inmates who reported being treated for TB were more likely to have had sex with a man while in prison and to report that, while in prison, they had a main sex partner. They were also 1.15 times more likely to have had sex with a person from the transgender community while in prison and 2.53 times more likely to report having been forced to have sex while in prison than those without a past history of being treated for TB. Future studies should attempt to determine the extent to which having an infectious disease such as TB impacts behavioural change with respect to behaviours practised by inmates.
- Published
- 2003
- Full Text
- View/download PDF
36. Prisoners' knowledge and attitude toward prophylactic treatment and therapy.
- Author
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Braithwaite R, Stephens TT, Cozza S, Whitfield R, and Braithwaite K
- Subjects
- Adult, Chi-Square Distribution, Humans, Interviews as Topic, Male, Middle Aged, Sexual Behavior, United States, AIDS-Related Opportunistic Infections prevention & control, Health Knowledge, Attitudes, Practice, Pneumonia, Pneumocystis prevention & control, Prisoners psychology
- Abstract
Identifying factors that hinder an inmate's compliance with Pneumocystis carinii pneumonia (PCP) prophylaxis therapy can be critical in preventing or decreasing the occurrence of PCP in this population. Anticipated factors include lack of knowledge about PCP and its proposed treatment, fear of the adverse effects of prophylaxis therapy, and lack of trust in the correctional facility medical team. Structured interviews were administered to HIV-positive male inmates chosen randomly (n = 104) at a medium- to maximum-security medical correctional facility located in the western portion of the United States. A basic "HIV 101 and Early Intervention" program encompassed the presentation of HIV facts and knowledge as well as safer sex practices. The results revealed that 95% of the respondents were knowledgeable about PCP and the side effects of their medications, and 56% of the respondents were afraid of the medications' side effects. Significant differences based on age were recorded for several specific knowledge questions, including the preventable nature of PCP.
- Published
- 1998
- Full Text
- View/download PDF
37. [High-resolution ultrasonography in the study of carpal tunnel syndrome].
- Author
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Ferrari FS, Della Sala L, Cozza S, Guazzi G, Belcapo L, Mariottini A, Bolognini A, and Stefani P
- Subjects
- Humans, Sensitivity and Specificity, Ultrasonography, Carpal Tunnel Syndrome diagnostic imaging
- Abstract
We investigated the reliability of some US signs in the diagnosis of the carpal tunnel syndrome. We carried out a single-blind study with 13-MHz high resolution probes and electromyography on 132 patients with clinical evidence of the carpal tunnel syndrome; a control group of 20 asymptomatic patients was also submitted to US. Eighty-six of 107 patients with US signs of the carpal tunnel syndrome were then submitted to surgical decompression (resection of the transverse carpal ligament), while the extant 21 patients underwent conservative treatment and clinical follow-up. To diagnose the carpal tunnel syndrome, we considered the following US patterns: median nerve changes (swelling before its entrance into the carpal tunnel and flattening in the tunnel itself), palmar bowing of the flexor retinaculum, thickening of the transverse carpal ligament and increased depth of the carpal tunnel, as measured from the apex of the transverse carpal ligament convexity to the underlying carpal bone. Median nerve changes were unreliable signs and were missing in many cases: only 45 of 107 patients exhibited median nerve swelling before and/or its flattening in the carpal tunnel (42%). Such indirect signs as the thickening of the transverse carpal ligament in chronic cases were demonstrated in 94 of 107 patients with the carpal tunnel syndrome (88%) and canal deepening in all unilateral carpal tunnel syndromes was shown in 92 of 107 patients (87%); both these signs proved to be much more reliable. The palmar bowing of the flexor retinaculum was also difficult to demonstrate in surgical patients or in those with connective tissue fibrosis within the tunnel: this sign was demonstrated in 80 of 107 patients with the carpal tunnel syndrome confirmed with electromyography (75%). Tanzer and Rietze reported median nerve changes observed at surgery in 43% and 66% of their patients, respectively. Recent MR findings in asymptomatic wrists have demonstrated that the normal median nerve has an elliptical shape inside the carpal tunnel. To conclude, high resolution US exhibited 96% sensitivity, 95% specificity and 93% diagnostic accuracy and proved to play a major role in the diagnosis of the carpal tunnel syndrome.
- Published
- 1997
38. [Role of Doppler color in the differential diagnosis of benign and malignant adenopathies].
- Author
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Ferrari FS, Cozza S, Guazzi G, Della Sala L, Leoncini L, Lazzi S, and Stefani P
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Lymphatic Diseases diagnostic imaging, Lymphatic Metastasis diagnostic imaging, Ultrasonography, Doppler, Color
- Abstract
The diagnosis of enlarged lymph nodes is of the utmost importance especially in the treatment planning of cancer patients. US yields such morphological findings as node size, longitudinal/transverse diameter ratio, hilum visibility and cortical thickness, which however do not permit the differential diagnosis of benign from malignant forms. Some authors tried to distinguish inflammatory enlargement from metastatic forms on the basis of color Doppler findings, with conflicting and questionable results. We investigated the potentials of color Doppler US in the differential diagnosis of benign and malignant lymph node enlargement using morphological data and flow measurements in lymphatic hilum vessels. The palpable superficial lymph nodes of 70 patients were studied with color Doppler with a linear probe (7.5-10 MHz) equipped for Doppler flow measurements. The largest lymph node was studied in multiple enlargement. The final diagnosis was made with US-guided cytology and/or excisional biopsy. The venous hilar vessels were depicted with color Doppler US in 44/45 patients with lymphadenitis and only in 1/17 patients with metastatic enlargement. Spectral Doppler exams of the hilar arteries showed flows with a wide telediastolic component in lymphadenitis (relative RI:0.58), while flow was rapid and with poor telediastolic component (relative RI:0.84) in metastatic enlargement. Average RI was 0.62 in Hodgkin's lymphomas and 0.71 in all the other lesions. We conclude that the distortion and compression of the main hilar vessels in metastatic lymph node enlargement often prevents color Doppler depiction of venous vessels. Moreover, the compression and distortion of the intranodal capillary network (the "mass" effect) often results in increased RI, as detected with power Doppler in the lymphatic hilum. Even though color Doppler US studies of the hemodynamic changes in the hilar vessels need further validation in larger series of cases, our preliminary results suggest interesting potentials in distinguishing inflammatory from metastatic enlargement, which differentiation remains nevertheless difficult especially in Hodgkin's lymphoma.
- Published
- 1997
39. [Ileal occlusion with strangulation: importance of ultrasonography findings of the dilated loop with intraluminal fluid-fluid resulting from sedimentation].
- Author
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Cozza S, Ferrari FS, Stefani P, Saporetti N, Fagioli A, Lenucci U, and Isolani G
- Subjects
- Female, Humans, Male, Middle Aged, Ultrasonography, Ileal Diseases diagnostic imaging, Intestinal Obstruction diagnostic imaging
- Abstract
To identify some dynamic or morphological patterns for the diagnosis of small bowel obstruction by hernia, adhesions or volvulus, we submitted to ultrasonography (US) 61 patients with clinical and radiographic syndromes of mechanical small bowel obstruction. The cause of obstruction was demonstrated in 58 patients-namely, with surgery in 56 patients and further instrumental examinations in 2. Three patients died before surgery. In our series, small bowel obstruction with strangulation was demonstrated at surgery in 31/56 patients. In 27/31 patients, US showed the coexistence of dilated loops with different kinetic behavior in the abdominal cavity-i.e., the simultaneous presence of akinetic loops with an intraluminal fluid-fluid level by sediment and peristaltic loops with solid particles in suspension. In 4/31 patients with strangulating small bowel obstruction. US provided no useful elements to explain the mechanism of obstruction. The US pattern of fluid-fluid levels due to intraluminal sediment in all the intestinal mass above the occluded segment was observed in 6/6 patients with uncompensated mechanical intestinal obstruction. This sign is due to the absence of intestinal muscular activity in the late stages of mechanical intestinal obstruction; its value is purely prognostic. To conclude, the US pattern of fluid-fluid levels by sediment diffused in the whole intestinal mass provides no useful elements to explain the cause of obstruction: on the contrary, the US pattern characterized by isolated intraluminal fluid-fluid levels or by the association of akinetic and peristaltic loops in the abdominal cavity appears pathognomonic of strangulating obstruction caused by volvulus, adhesion or hernia, with 87% sensitivity and 100% specificity.
- Published
- 1996
40. [Color Doppler echography in the study of obstruction-related lung collapse].
- Author
-
Ferrari FS, Cozza S, Baldini R, Boni S, Drudi F, Stefani P, and Passariello R
- Subjects
- Adult, Aged, Bronchi diagnostic imaging, Bronchial Neoplasms complications, Bronchial Neoplasms diagnostic imaging, Female, Humans, Lung blood supply, Male, Middle Aged, Pulmonary Atelectasis etiology, Ultrasonography, Doppler, Color instrumentation, Ultrasonography, Doppler, Color methods, Lung diagnostic imaging, Pulmonary Atelectasis diagnostic imaging
- Abstract
The typical US pattern of obstructive atelectasis consists in a triangular hypoechoic area with anechoic bands inside related to fluid-filled bronchial structures--the US fluid bronchogram sign. According to some authors, this US sign within a chest mass indicates pulmonary parenchyma disease. Furthermore, it suggests the diagnosis of lung collapse. Sixty-one patients with obstructive atelectasis confirmed with conventional radiography, conventional and computed tomography, and bronchoscopy were submitted to B-mode and color-Doppler US to assess the importance of the US fluid bronchogram sign in obstructive pulmonary atelectasis. In this condition, B-mode US showed tubular anechoic bands in 59/61 patients. Power Doppler venous sampling showed a Doppler spectrum with marked phase oscillations. Arterial sampling showed a Doppler spectrum with high distal impedance-with poor or totally absent diastolic component. To conclude, in the atelectasis area, B-mode US showed in 96% of patients some anechoic bands with no apparent pulsatility. Color-Doppler showed color flow in 100% of cases, which confirmed the vascular nature of the masses. Thus, the US fluid bronchogram, which is frequently described in the literature, was never observed in our series. Power Doppler spectral flow analysis can be useful in the diagnosis of obstructive atelectasis because it depicts the hemodynamics of atelectasis parenchyma. Indeed, the arterial spectrum with high distal resistance is consistent with the effects of hypoxia on intra-atelectatic blood vessels. Further research is necessary to assess the role of color-Doppler US in the hemodynamic study of intra-atelectatic vessels. However, our preliminary results open new perspectives for the acquisition of physiopathologic data on abnormal blood flow in obstructive atelectasis.
- Published
- 1996
41. [Aneurysm of the right hepatic artery. Diagnosis by color Doppler echography].
- Author
-
Cozza S, Cosi A, Gamberucci G, Isolani G, Cappelli A, Pieraccini M, Civeli L, Bianciardi A, and Stefani P
- Subjects
- Angiography, Digital Subtraction, Female, Humans, Middle Aged, Ultrasonography, Doppler, Color, Aneurysm diagnostic imaging, Hepatic Artery diagnostic imaging
- Published
- 1995
42. [Transrectal color Doppler in calcified neoplasms of the bladder. Report of a case].
- Author
-
Cozza S, Ferrari FS, Baldi C, Ricotti U, Nucci F, Isolani G, and Bernardini M
- Subjects
- Aged, Calcinosis etiology, Carcinoma, Papillary complications, Humans, Male, Urinary Bladder Diseases etiology, Urinary Bladder Neoplasms complications, Calcinosis diagnostic imaging, Carcinoma, Papillary diagnostic imaging, Ultrasonography, Doppler, Color, Urinary Bladder Diseases diagnostic imaging, Urinary Bladder Neoplasms diagnostic imaging
- Published
- 1995
43. [Hydatidosis located in the clavicle. The echographic observation of a case].
- Author
-
Cozza S, Ferrari FS, Guazzi G, Pacini M, and Isolani G
- Subjects
- Aged, Humans, Male, Radiography, Ultrasonography, Bone Diseases diagnostic imaging, Clavicle diagnostic imaging, Echinococcosis diagnostic imaging
- Published
- 1994
44. Risperidone in adolescents.
- Author
-
Cozza SJ and Edison DL
- Subjects
- Adolescent, Antipsychotic Agents adverse effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Hospitalization, Humans, Isoxazoles adverse effects, Male, Piperidines adverse effects, Psychotic Disorders psychology, Risperidone, Antipsychotic Agents therapeutic use, Isoxazoles therapeutic use, Piperidines therapeutic use, Psychotic Disorders drug therapy, Schizophrenia drug therapy, Schizophrenic Psychology
- Published
- 1994
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