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137 results on '"Coviello, V"'

1. The Physics of Granular Natural Flows in Volcanic Environments

Author

Rodríguez-Liñán, G. M., Torres-Orozco, R., Márquez, V. H., Capra, L., Coviello, V., Herrera Guzman, Rafael, Managing Editor, Arizmendi, Octavio, Editorial Board Member, Hernandez, Arturo, Editorial Board Member, Moreles, Miguel Angel, Editorial Board Member, Nakamura, Miguel, Editorial Board Member, and Hernández-Dueñas, Gerardo, editor

Published
2022
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5. Nanostructured ultra-thin patches for ultrasound-modulated delivery of anti-restenotic drug

Author

Vannozzi L, Ricotti L, Filippeschi C, Sartini S, Coviello V, Piazza V, Pingue P, La Motta C, Dario P, and Menciassi A

Subjects
restenosis, micro/nano therapeutic systems, thin films, layer-by-layer polyelectrolytes, barium titanate nanoparticles, drug delivery, ultrasound., Medicine (General), R5-920
Abstract

Lorenzo Vannozzi,1 Leonardo Ricotti,1 Carlo Filippeschi,2 Stefania Sartini,3 Vito Coviello,3 Vincenzo Piazza,4 Pasqualantonio Pingue,5 Concettina La Motta,3 Paolo Dario,1 Arianna Menciassi1 1The BioRobotics Institute, Scuola Superiore Sant’Anna, 2Center for MicroBioRobotics at SSSA, Istituto Italiano di Tecnologia, Pontedera, 3Department of Pharmacy, University of Pisa, 4Center for Nanotechnology Innovation at NEST, Istituto Italiano di Tecnologia, 5NEST, Scuola Normale Superiore, Istituto Nanoscienze-CNR, Pisa, Italy Abstract: This work aims to demonstrate the possibility to fabricate ultra-thin polymeric films loaded with an anti-restenotic drug and capable of tunable drug release kinetics for the local treatment of restenosis. Vascular nanopatches are composed of a poly(lactic acid) supporting membrane (thickness: ~250 nm) on which 20 polyelectrolyte bilayers (overall thickness: ~70 nm) are alternatively deposited. The anti-restenotic drug is embedded in the middle of the polyelectrolyte structure, and released by diffusion mechanisms. Nanofilm fabrication procedure and detailed morphological characterization are reported here. Barium titanate nanoparticles (showing piezoelectric properties) are included in the polymeric support and their role is investigated in terms of influence on nanofilm morphology, drug release kinetics, and cell response. Results show an efficient drug release from the polyelectrolyte structure in phosphate-buffered saline, and a clear antiproliferative effect on human smooth muscle cells, which are responsible for restenosis. In addition, preliminary evidences of ultrasound-mediated modulation of drug release kinetics are reported, thus evaluating the influence of barium titanate nanoparticles on the release mechanism. Such data were integrated with quantitative piezoelectric and thermal measurements. These results open new avenues for a fine control of local therapies based on smart responsive materials. Keywords: restenosis, micro/nanotherapeutic systems, thin films, layer-by-layer polyelectrolytes, barium titanate nanoparticles, drug delivery, ultrasound

Published
2015

11. Strumentazione colate rapide

Author

Marchi L., Coviello V., and Crema S.

Subjects
telecamera, sistema di allertamento, colata detritica, monitoraggio, sensore
Abstract

Nell'ampio di una comprensiva monografia dedicata al monitoraggio delle frane, il paragrafo descrive i principali tipi di sensori utilizzabili la misura delle colate detritiche per finalità di studio e di allertamento

Published
2021

12. Il monitoraggio delle colate detritiche

Author

Marchi L., Crema S., and Coviello V.

Subjects
sistemi di allertamento, colata detritica, monitoraggio
Abstract

Il contributo illustra le principali problematiche relative al monitoraggio delle colate detritiche (per finalità sia di ricerca che di allertamento) con riferimento al contributo degli autori alle Linee guida SNPA per il monitoraggio delle frane.

Published
2021

13. Colata detritica del rio Gadria (Provincia Autonoma di Bolzano)

Author

Marchi L. and Coviello V.

Subjects
Rio Gadria, colata detritica, monitoraggio
Abstract

Nell'ampio di una comprensiva monografia dedicata al monitoraggio delle frane, il paragrafo descrive il bacino attrezzato del Rio Gadria ed i principali dati in esso raccolti

Published
2021

14. Il monitoraggio microsismico dello sperone roccioso di Capanna J.A. Carrel

Author

Arattano M. (1), Chiarle M. (1), Coviello V. (1), Morra di Cella U. (2), and Pogliotti P. (2)

Subjects
Cervino, cambiamento climatico, geofoni, crolli di roccia
Abstract

I cambiamenti climatici stanno determinando un aumento dell'instabilità dei versanti rocciosi di alta quota. Questo fenomeno è divenuto particolarmente evidente a partire dalla torrida estate 2003, quando numerosi massicci alpini hanno manifestato un'attività di crolli senza precedenti, mettendo a rischio escursionisti, alpinisti e infrastrutture di alta quota. Nell'ambito dei progetti Interreg Alcotra PERMAdataROC e MASSA, il CNR-IRPI e ARPA Valle d'Aosta, con il supporto finanziario e logistico della Regione Valle d'Aosta, hanno realizzato presso la Capanna J.A. Carrel un sistema sperimentale di monitoraggio microsismico delle deformazioni dell'ammasso roccioso, in relazione all'andamento della temperatura. La formazione e l'apertura di fratture nella roccia, così come il distacco di blocchi rocciosi, sono infatti fenomeni che producono vibrazioni che possono essere percepite e registrate da geofoni: l'installazione di una rete di sensori adeguatamente posizionati può consentire di individuare non solo quando, ma anche dove avvengono i fenomeni di interesse. Lo studio ha evidenziato una correlazione tra i "rumori" sismici prodotti dallo sviluppo di stati tensionali della roccia e/o da crolli, da un lato, e le variazioni di temperatura, dall'altro. La brevità dello studio non ha tuttavia consentito di verificare il possibile utilizzo applicativo dei segnali registrati dai geofoni quali precursori di eventi di crollo.

Published
2021

16. Cancer incidence in children and young adults living in industrially contaminated sites: from the Italian experience to the development of an international surveillance system

Author

Iavarone, I, Buzzoni, C, Stoppa, G, Steliarova-Foucher, E, Ardizzone, A, Barchielli, A, Borciani, E, Boschetti, L, Brustolin, A, Caiazzo, M, Candela, G, Carrozzi, G, Cavalieri D'Oro, L, Cesaraccio, R, Contiero, P, Contrino, Ml, Coviello, V, Falcini, F, Fanetti, Ac, Ferretti, S, Filiberti, R, Galasso, R, Giorno, A, Grappasonni, I, Magoni, M, Mangone, L, Mazzoleni, G, Melcarne, A, Michiara, M, Minerba, A, Pannozzo, F, Piffer, S, Pisani, S, Ricci, P, Rugge, M, Russo, Ag, Sacerdote, C, Sanpietro, G, Sciacca, S, Stracci, F, Sutera, A, Tagliabue, G, Tumino, R, Usala, M, Vitale, F, and Zanetti, R.

Subjects
Adult, Male, Internationality, Adolescent, Epidemiology, Incidence, Environmental and Occupational Health, Infant, Newborn, Socio-culturale, Infant, Europe, Young Adult, Italy, Child, Preschool, Neoplasms, Public Health, Environmental and Occupational Health, Humans, Industry, Female, Public Health, Child, Environmental Pollution, Environmental Monitoring
Abstract

this paper is based upon work from COST Action ICSHNet. Children's environmental health is on the 2030 Agenda for Sustainable Development. The incidence of childhood cancer is increasing worldwide and in Europe. Yet, the aetiology of most childhood cancers, including the role of environmental carcinogens, is still largely unknown. Contaminated areas, especially of industrial origin, are of high concern due to complex mix of hazardous pollutants and their potential health impacts on human populations, notably in children.to describe cancer risk in children and young adults (YA) residing in national priority contaminated sites (NPCSs) in Italy and to provide a suitable framework for a development of cancer surveillance in industrially contaminated sites (ICSs) in Europe.this study is based on a collaborative work of the Italian Institute of Health (ISS) and the Italian Association of Cancer Registries (AIRTUM), in the context of the SENTIERI project (Epidemiological study of residents in National Priority Contaminated Sites). Incidence rates were standardised according to the European standard population. The number of observed cases was compared to the expected cases derived from the age-, sex-, and cancer-specific incidence rates of the national pool of AIRTUM registries for the period 2006-2013. Standardized incidence ratios (SIRs) and 90% confidence intervals (CIs) were computed. The study reports the cancer profile in all combined 28 NPCSs covered by 22 cancer registries.1,050 cases of malignant tumours (MTs) were recorded among 3,161,786 person-years in people aged 0-29 years in 28 NPCSs (SIR: 1.03; 90%CI 0.98-1.09), with an age-standardised incidence rate of 317 per million. Excess risks were observed for: MT of the central nervous system in the age-group1 year (SIR: 3.2; 90%CI 1.4-6.3); soft tissue sarcoma in the age-group 0-14 years (SIR: 1.6; 90%CI 1.1-2.3); acute myeloid leukaemia in the agegroup 0-14 years (SIR: 1.7; 90%CI 1.1-2.4); non-Hodgkin lymphoma in the age-group 20-24 years (SIR 1.5; 90%CI 1.1-2.1), and germ cell tumours of male gonads in the age-group 20-29 years (SIR: 1.33; 90%CI 1.1-1.5). A deficit of cases was observed for Hodgkin lymphomas in the age-group 20-29 years (SIR 0.8; 90%CI 0.6-1.0).this study, which is based on standardized methods and accredited information sources, supports the hypothesis that living in an NPCS increases the risk of some cancer types in children and young adults. Further work will concern groups of NPCSs characterised by common sources of contamination/key carcinogenic pollutants. In fact, in a novel project proposal we aim to monitor the cancer profile in children living in ICSs in Europe. The new project, based on the SENTIERI-AIRTUM methodology, will build on the networking activities of the COST Action on Industrially Contaminated Sites and Health Networking (ICSHNet) and childhood cancer studies coordinated by the International Agency for research on Cancer (IARC).

Published
2018

19. The anatomy of a pyroclastic density current: the 10 July 2015 event at Volcán de Colima (Mexico)

Author

Ministerio de Economía y Competitividad (España), Universidad Nacional Autónoma de México, Capra, Lucia, Sulpizio, Roberto, Márquez-Ramirez, V. H., Coviello, V., Doronzo, Domenico Maria, Arambula-Mendoza, R., Cruz, S., Ministerio de Economía y Competitividad (España), Universidad Nacional Autónoma de México, Capra, Lucia, Sulpizio, Roberto, Márquez-Ramirez, V. H., Coviello, V., Doronzo, Domenico Maria, Arambula-Mendoza, R., and Cruz, S.

Abstract

Pyroclastic density currents (PDCs) represent one of the most dangerous phenomena occurring in explosive volcanic eruptions, and any advance in the physical understanding of their transport and sedimentation processes can contribute to improving their hazard assessment. The 10–11 July 2015 eruption at Volcán de Colima provided a unique opportunity to better understand the internal behaviour of PDCs based on seismic monitoring data. On 10 July 2015, the summit dome collapsed, producing concentrated PDCs that filled the main channel of the Montegrande ravine. A lahar monitoring station installed 6 km from the volcano summit recorded a PDC before being completely destroyed. Real-time data acquisition from a camcorder and a geophone that were part of the station, along with field observations and grain-size data of the pyroclastic deposits, are used here to interpret the internal flow structure and time-variant transport dynamics of low-volume, valley-confined concentrated PDCs. The PDC that reached the monitoring station moved at a velocity of ~ 7 m/s and filled a 12-m-deep channel. The outcrops show massive, block-and-ash flow deposits with trains of coarse clasts in the middle and towards the top of the depositional units. The seismic record gathered with the geophone was analysed for the time window when the flow travelled past the sensor. The geophone record was also compared with the recordings of a broadband seismic station located nearby. Two main frequency ranges were recognised which could be correlated with the basal frictional forces exerted by the flow on the channel bed (10–20 Hz) and a collisional regime (20–40 Hz) interpreted to be associated with a clast segregation process (i.e. kinematic squeezing). This latter regime promoted the upward migration of large blocks, which subsequently deviated towards the margin of the flow where they interacted with the sidewall of the main channel. The energy calculated for both seismic components shows that the colli

Published
2018

20. Survival of cancer patients in Italy [La sopravvivenza dei pazienti oncologici in Italia [La sopravvivenza dei pazienti oncologici in Italia]

Author

Coviello, V, Buzzoni, C, Fusco, M, Barchielli, A, Cuccaro, F, De Angelis, R, Giacomin, A, Luminari, S, Randi, G, Mangone, L, and AIRTUM Working Group

Subjects
Male, Epidemiology, Incidence, Environmental and Occupational Health, Medical Oncology, Survival Rate, Italy, Neoplasms, Female, Humans, Prevalence, Registries, Retrospective Studies, Public Health, Environmental and Occupational Health, Public Health
Published
2017

21. [The contribution of the Italian association of cancer registries (AIRTUM)]

Author

Crocetti, Emanuele, Buzzoni, Carlotta, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos AP, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Abstract

The study of cluster requires the ability to identify, with accuracy and completeness, the health events of interest and their geographical location and time of occurrence. For rare and complex diseases, such as childhood cancers, it is possible to observe a significant health migration from the place of residence, which makes the detection even more complex. The best tool to identify these rare diseases is represented by cancer registries (CRs). In fact, CRs collect, through many sources, information related to tumours that arise in the population resident in their areas of activity. The number of the sources of information has increased thanks to the computerization of health services. The availability of multiple sources of information increases the completeness of data collection overcoming the limits of a single source, and makes it possible to describe the diagnostic-therapeutic course and the outcome of the cases. Among all data sources, for childhood cancers the model 1.01, which summarize the clinical information of the cases treated in one of the Italian Association of paediatric haematology and oncology (AIEOP) centres, is relevant. Moreover, CRs produce reliable and comparable data due to the use of international rules and classifications for the definition of the topography and morphology of cancer, for the date of diagnosis, and for quality checks. In Italy, the Italian association of cancer registries (AIRTUM) coordinates the activities of 45 population CRs, both general and specialized (by age or tumour type). AIRTUM involves a population of over 6.7 million citizens under the age of 20 years, approximately 60% of the total resident population. AIRTUM plays a role of coordination, support, and harmonization for Italian CRs through training, accreditation, and a shared database, it promotes and participates in national and international collaboration involving scientific societies (AIEOP, Italian Association of medical oncology - AIOM, Italian Federation of volunteer-based cancer organisations - FAVO) and institutions (Italian national Institute of health, Italian national cancer institute of Milan) and performs analysis on key epidemiological indicators (incidence, mortality, survival, and prevalence). The AIRTUM database contains 19,650 cancer cases in child/ adolescent patients diagnosed from 1967 to 2011. The epidemiology of childhood cancers has been the subject of two AIRTUM monographs published in 2008 and in 2013 in collaboration with AIEOP; the latter includes specific contributions on polluted sites, on the psychological side, and on the experience of the parents of young cancer patients. The collaboration between different professionals, needs, and knowledge is the policy followed by AIRTUM to build up a complete picture of cancer epidemiology, even of childhood cancer, in Italy.

Published
2016

22. Early-stage diffuse large B-cell lymphoma of the submental region: a case report and review of the literature

Author

Patini, Romeo, Coviello, V., Riminucci, M., Corsi, A., Cicconetti, A., Patini, R. (ORCID:0000-0001-7358-8763), Patini, Romeo, Coviello, V., Riminucci, M., Corsi, A., Cicconetti, A., and Patini, R. (ORCID:0000-0001-7358-8763)

Abstract

Lymphomas represent the third most common group of malignant lesions in the oral cavity and maxillofacial region, following squamous cell carcinoma and salivary gland neoplasm[1, 2]. Traditionally, lymphomas are divided into two subtypes, Hodgkin lymphomas (HL) and non-Hodgkin lymphomas (NHL)[3]. The diffuse large B-cell lymphoma (DLBCL) is a rapidly aggressive NHL constituted by big lymphoid cells that can appear as a nodal or extra-nodal disease; about 4% of DLBCL are initially confined to extra-nodal sites[4]. The oral and maxillofacial region is the second most common extra-nodal site, and half of the cases are located in Waldeyer's ring[3]. The tumour may present clinical symptoms and radiographic findings as local swelling, pain or discomfort, ulcer and bone resorption mimicking other pathologic lesions such as periodontal disease, pericoronitis, apical radiolucencies or dental abscesses[5]. We report a case of a patient with DLBCL of the submental region staged at I AE according to the Ann Arbor lymphoma staging system.

Published
2017

23. Surgical ciliated cyst 12 years after Le Fort I maxillary advancement osteotomy: a case report and review of the literature

Author

Coviello, V., Zareh Dehkhargani, S., Patini, Romeo, Cicconetti, A., Patini, R. (ORCID:0000-0001-7358-8763), Coviello, V., Zareh Dehkhargani, S., Patini, Romeo, Cicconetti, A., and Patini, R. (ORCID:0000-0001-7358-8763)

Abstract

The surgical ciliated cyst, which is also known with the terms ‘post-operative maxillary cyst (PMC)’ or ‘paranasal cyst’, was originally reported by Kubo in 1927 and well-described in Japanese literature since the 1980s. PMC is a locally aggressive lesion that appears as a long-term delayed complication, arising from years to decades, after surgery or trauma in the maxillary sinus region such as midfacial osteotomies and fractures or orthognatic surgery. Although this cyst is rarely reported in Western population, it constitutes 20% of oral cysts in Japan. PMC usually appears as a swelling that may cause expansion of vestibular, palatine or both bone cortical plates, and pain in the adjacent facial area of buccal vertical releasing incisions; formation of fistulas has also been reported. In case of significant cyst growth, other symptoms may include nasal obstruction, rhinorrhea, dysomia, exophthalmos and ocular displacement. We report the only case of a surgical ciliated cyst that developed in a Caucasian patient 12 years after a Le Fort I maxillary advancement osteotomy.

Published
2017

24. Italian cancer figures, report 2014: Prevalence and cure of cancer in Italy

Author

Adamo, M., Alessi, D., Aletta, P., Amodio, R., Andreone, S., Angelin, T., Anghinoni, E., Annulli, M., Arciprete, C., Artioli, M., Autelitano, M., Baili, P., Balducci, C., Baracco, M., Baracco, S., Battisti, W., Bella, F., Bellatalla, C., Bellini, A., Belluardo, C., Benatti, P., Benedetto, G., Benfatto, L., Bernazza, E., Bianconi, F., Biavati, P., Bidoli, E., Birri, S., Bizzoco, S., Bonelli, L., Bonini, A., Borciani, E., Bordini, M., Bovo, E., Bozzani, F., Braghiroli, B., Brucculeri, M., Brunori, V., Bucalo, G., Bucchi, L., Bugliarello, E., Bulatko, A., Busco, S., Busso, P., Buzzoni, C., Calabrese, A., Calabretta, L., Caldarella, A., Candela, G., Cannone, G., Canu, L., Caparelli, M., Capocaccia, R., Cappelletti, M., Caprara, L., Carboni, D., Carletti, N., Caroli, S., Cascio, M., Cascone, G., Casella, C., Castaing, M., Cavalieri, D., L, Cecconami, L., Celesia, M., Cena, T., Cercato, M., Cesaraccio, R., Chiesa, R., Cirilli, C., Cocchioni, M., Codazzi, T., Cogno, R., Colamartini, A., Colanino, Z., A, Cometti, I., Contiero, P., Contrino, M., Corbinelli, A., Cordaro, C., Corti, M., Costa, A., Costarelli, D., Coviello, V., Crapanzano, G., Cremone, L., Crocetti, E., Cuccaro, F., Curatella, S., Cusimano, R., D Alò, D., Dal, C., Dal, T., Cin, A., Dal, M., Davini, C., Dottori, D., De, M., Angelis, R., Santis, D., De, E., Valiere, E., Dei, T., Demurtas, G., Devigili, E., Felice, D., Di, E., Grazia, L., Gregorio, D., Di, C., Norcia, R., Prima, D., Dinaro, Y., Distefano, R., Doa, N., Domati, F., Fabiano, S., Facchinelli, G., Falcini, F., Falk, M., Fanetti, A., Fattoruso, S., Federico, M., Ferrari, F., Ferrari, L., Ferretti, S., Fidelbo, M., Filipazzi, L., Fiore, A., Fiori, G., Foca, F., Forgiarini, O., Foschi, R., Francisci, S., Frasca, G., Frassoldi, E., Fusco, M., Gada, D., Garrone, E., Gasparotti, C., Gatta, G., Gatti, L., Gaudiano, C., Gennaro, V., Gentilini, M., Gerevini, C., Ghilardi, S., Ghisleni, S., Giacomin, A., Giavazzi, L., Gigli, A., Gilardi, F., Giorgetti, S., Giorgi, R., P, Giubelli, C., Giuliani, O., Giurdanella, M., Gola, G., Goldoni, C., Golizia, M., Greco, A., Guarda, L., Guttadauro, A., Guzzinati, S., Iachetta, F., Iannelli, A., Ieni, A., Intrieri, T., Kaleci, S., Rosa, L., F, Lando, C., Lavecchia, A., Lazzarato, F., Rose, L., Leone, A., Leone, R., Lonati, F., Lucchi, S., Luminari, S., Macci, L., Macerata, V., Madeddu, A., Maffei, S., Maghini, A., Magnani, C., Magnani, G., Magoni, M., Mallone, S., Mameli, G., Mancini, S., Mancuso, P., Mangone, L., Manneschi, G., Mannino, R., Mannino, S., Marani, E., Marchesi, C., Mariani, F., Martorana, C., Marzola, L., Maspero, S., Maule, M., Mazzei, A., Mazzoleni, G., Mazzucco, G., Melcarne, A., Merletti, F., Merlo, E., Michiara, M., Migliari, E., Minerba, S., Minicuzzi, A., Mizzi, M., Monetti, D., Morana, G., Moroni, E., Mosso, M., Muni, A., Mura, F., Natali, M., Negrino, L., Nemcova, L., Nicita, C., Ocello, C., Pala, F., Palumbo, M., Panciroli, E., Panico, M., Pannozzo, F., Pascucci, C., Pasolini, A., Pastore, G., Patriarca, S., Pedroni, M., Perrotta, C., Pesce, P., Petrinelli, A., Petrucci, C., Pezzarossi, A., Pezzuto, L., Piffer, S., Pinon, M., Antonio Pinto, Pintori, N., Pirani, M., Pirino, D., Pironi, V., Ponz, D., Leon, M., Prandi, R., Prazzoli, R., Puleio, M., Puppo, A., Quarta, F., Quattrocchi, M., Ramazzotti, V., Rashid, I., Ravaioli, A., Ravazzolo, B., Ravegnani, M., Reggiani Bonetti, L., Ricci, P., Rinaldi, E., Rizzello, R., Rognoni, M., Rollo, P., Roncaglia, F., Roncucci, L., Rosano, A., Rossi, F., Rossi, G., Rossi, M., Rossi, S., Rossini, S., Rosso, S., Rudisi, G., Ruggeri, M., Russo, A., Russo, M., Sacchettini, C., Sacchetto, L., Sacco, G., Sacerdote, C., Salvatore, S., Salvi, O., Sampietro, G., Santucci, C., Scheibel, M., Sciacca, S., Sciacchitano, C., Sciacchitano, S., Scuderi, T., Sechi, O., Seghini, P., Senatore, G., Serafini, G., Serraino, D., Sgargi, P., Sini, G., Sobrato, I., Soddu, M., Solimene, C., Spano, F., Spata, E., Sperduti, I., Spinosa, S., Staiti, R., Stocco, C., Stracci, F., Sunseri, R., Sutera, S., Tagliabue, G., Tamburo, L., Tamburrino, S., Taranto, V., Terracini, B., Tisano, F., Tittarelli, A., Tognazzo, S., Torrisi, A., Traina, A., Trama, A., Trapani, C., Tschugguel, B., Tumino, R., Usala, M., Vacirca, S., Valerio, O., Valla, K., Varvarà, M., Vasquez, E., Vassante, B., Vattiato, R., Vercelli, M., Vercellino, P., Vicentini, M., Villa, M., Virdone, S., Francesco Vitale, Vitale, M., Vitali, B., Vitali, M., Vitarelli, S., Zanchi, A., Zanetti, R., Zani, G., Zanier, L., Zappa, M., Zarcone, M., Zevola, A., Zorzi, M., Zucchetto, A., Zucchi, A., Adamo, MS, Alessi, D, Aletta, P, Amodio, R, Andreone, S, Angelin, T, Anghinoni, E, Annulli, ML, Arciprete, C, Artioli, ME, Autelitano, M, Baili, P, Balducci, C, Baracco, M, Baracco, S, Battisti, W, Bella, F, Bellatalla, C, Bellini, A, Belluardo, C, Benatti, P, Benedetto, G, Benfatto, L, Bernazza, E, Bianconi, F, Biavati, P, Bidoli, E, Birri, S, Bizzoco, S, Bonelli, L, Bonini, A, Borciani, E, Bordini, M, Bovo, E, Bozzani, F, Braghiroli, B, Brucculeri, MA, Brunori, V, Bucalo, G, Bucchi, L, Bugliarello, E, Bulatko, A, Busco, S, Busso, P, Buzzoni, C, Calabrese, A, Calabretta, L, Caldarella, A, Candela, G, Cannone, G, Canu, L, Caparelli, M, Capocaccia, R, Cappelletti, M, Caprara, L, Carboni, D, Carletti, N, Caroli, S, Cascio, MA, Cascone, G, Casella, C, Castaing, M, Cavalieri, d'Oro, L, Cecconami, L, Celesia, MV, Cena, T, Cercato, MC, Cesaraccio, R, Chiesa, R, Cirilli, C, Cocchioni, M, Codazzi, T, Cogno, R, Colamartini, A, Colanino, Ziino, A, Cometti, I, Contiero, P, Contrino, ML, Corbinelli, A, Cordaro, C, Corti, M, Costa, A, Costarelli, D, Coviello, V, Crapanzano, G, Cremone, L, Crocetti, E, Cuccaro, F, Curatella, S, Cusimano, R, D'Alò, D, Dal, Cappello, T, Dal, Cin, A, Dal, Maso, L, Davini, C, De, Dottori, M, De, Angelis, R, De, Santis, E, De, Valiere, E, Dei, Tos, AP, Demurtas, G, Devigili, E, Di, Felice, E, di, Grazia, L, Di, Gregorio, C, di, Norcia, R, Di, Prima, A, Dinaro, Y, Distefano, R, Doa, N, Domati, F, Fabiano, S, Facchinelli, G, Falcini, F, Falk, M, Fanetti, AC, Fattoruso, S, Federico, M, Ferrari, F, Ferrari, L, Ferretti, S, Fidelbo, M, Filipazzi, L, Fiore, AR, Fiori, G, Foca, F, Forgiarini, O, Foschi, R, Francisci, S, Frasca, G, Frassoldi, E, Fusco, M, Gada, D, Garrone, E, Gasparotti, C, Gatta, G, Gatti, L, Gaudiano, C, Gennaro, V, Gentilini, MA, Gerevini, C, Ghilardi, S, Ghisleni, S, Giacomin, A, Giavazzi, L, Gigli, A, Gilardi, F, Giorgetti, S, Giorgi, Rossi, P, Giubelli, C, Giuliani, O, Giurdanella, MC, Gola, G, Goldoni, CA, Golizia, MG, Greco, A, Guarda, L, Guttadauro, A, Guzzinati, S, Iachetta, F, Iannelli, A, Ieni, A, Intrieri, T, Kaleci, S, La, Rosa, F, Lando, C, Lavecchia, AM, Lazzarato, F, Le, Rose, L, Leone, A, Leone, R, Lonati, F, Lucchi, S, Luminari, S, Macci, L, Macerata, V, Madeddu, A, Maffei, S, Maghini, A, Magnani, C, Magnani, G, Magoni, M, Mallone, S, Mameli, G, Mancini, S, Mancuso, P, Mangone, L, Manneschi, G, Mannino, R, Mannino, S, Marani, E, Marchesi, C, Mariani, F, Martorana, C, Marzola, L, Maspero, S, Maule, M, Mazzei, A, Mazzoleni, G, Mazzucco, G, Melcarne, A, Merletti, F, Merlo, E, Michiara, M, Migliari, E, Minerba, S, Minicuzzi, A, Mizzi, M, Monetti, D, Morana, G, Moroni, E, Mosso, ML, Muni, A, Mura, F, Natali, M, Negrino, L, Nemcova, L, Nicita, C, Ocello, C, Pala, F, Palumbo, M, Panciroli, E, Panico, M, Pannozzo, F, Pascucci, C, Pasolini, A, Pastore, G, Patriarca, S, Pedroni, M, Perrotta, C, Pesce, P, Petrinelli, AM, Petrucci, C, Pezzarossi, A, Pezzuto, L, Piffer, S, Pinon, M, Pinto, A, Pintori, N, Pirani, M, Pirino, D, Pironi, V, Ponz, de, Leon, M, Prandi, R, Prazzoli, R, Puleio, M, Puppo, A, Quarta, F, Quattrocchi, M, Ramazzotti, V, Rashid, I, Ravaioli, A, Ravazzolo, B, Ravegnani, M, Reggiani-Bonetti, L, Ricci, P, Rinaldi, E, Rizzello, R, Rognoni, M, Rollo, PC, Roncaglia, F, Roncucci, L, Rosano, A, Rossi, F, Rossi, G, Rossi, M, Rossi, S, Rossini, S, Rosso, S, Rudisi, G, Ruggeri, MG, Russo, AG, Russo, M, Sacchettini, C, Sacchetto, L, Sacco, G, Sacerdote, C, Salvatore, S, Salvi, O, Sampietro, G, Santucci, C, Scheibel, M, Sciacca, S, Sciacchitano, C, Sciacchitano, S, Scuderi, T, Sechi, O, Seghini, P, Senatore, G, Serafini, G, Serraino, D, Sgargi, P, Sini, GM, Sobrato, I, Soddu, M, Solimene, C, Spano, F, Spata, E, Sperduti, I, Spinosa, S, Staiti, R, Stocco, C, Stracci, F, Sunseri, R, Sutera, Sardo, A, Tagliabue, G, Tamburo, L, Tamburrino, S, Taranto, V, Terracini, B, Tisano, F, Tittarelli, A, Tognazzo, S, Torrisi, A, Traina, A, Trama, A, Trapani, C, Tschugguel, B, Tumino, R, Usala, M, Vacirca, S, Valerio, O, Valla, K, Varvarà, M, Vasquez, E, Vassante, B, Vattiato, R, Vercelli, M, Vercellino, PC, Vicentini, M, Villa, M, Virdone, S, Vitale, F, Vitale, MF, Vitali, B, Vitali, ME, Vitarelli, S, Zanchi, A, Zanetti, R, Zani, G, Zanier, L, Zappa, M, Zarcone, M, Zevola, A, Zorzi, M, Zucchetto, A, and Zucchi, A

Subjects
Aged, 80 and over, Male, Medicine (all), Aged, Female, Humans, Italy, Middle Aged, Neoplasms, Prevalence, Registries, Survival Rate, Socio-culturale, Settore MED/42 - Igiene Generale E Applicata, 80 and over, cancer prevalence, cancer incidence, cancer in Italy
Abstract

This Report intends to estimate the total number of people still alive in 2010 after cancer diagnosis in Italy, regardless of the time since diagnosis, and to project these estimates to 2015. This study is also aimed to estimate the number of already cured cancer patients, whose mortality rates have become undistinguishable from that of the general population of the same age and sex.The study took advantage of the information from the AIRTUM database, which included 29 Cancer Registries (covering 21 million people, 35% of the Italian population). A total of 1,624,533 cancer cases diagnosed between 1976 and 2009 contributed to the study. For each registry, the observed prevalence was calculated. Prevalence for lengths of time exceeding the maximum duration of the registration and of the complete prevalence were derived by applying an estimated correction factor, the completeness index. This index was estimated by means of statistical regression models using cancer incidence and survival data available in registries with 18 years of observation or more. For 50 types or combinations of neoplasms, complete prevalence was estimated at 1.1.2010 as an absolute number and as a proportion per 100,000 inhabitants by sex, age group, area of residence, and years since diagnosis. Projections of complete prevalence for 1.1.2015 were computed under the assumption of a linear trend of the complete prevalence observed until 2010. Validated mixture cure models were used to estimate: the cure fraction, that is the proportion of patients who, starting from the time of diagnosis, are expected to reach the same mortality rate of the general population; the conditional relative survival (CRS), that is the cumulative probability of surviving some additional years, given that patients already survived a certain number of years; the time to cure, that is the number of years necessary so that conditional survival in the following five years (5-year CRS) exceeds the conventional threshold of 95% (i.e., mortality rates in cancer patients become undistinguishable compared to those of the general population); the proportion of patients already cured, i.e., people alive since a number of years exceeding time to cure.As of 1.1.2010, it was estimated that 2,587,347 people were alive after a cancer diagnosis, corresponding to 4.4% of the Italian population. A relevant geographical heterogeneity emerged, with a prevalence above 5% in northern registries and below 4% in southern areas. Men were 45% of the total (1,154,289) and women 55% (1,433,058). In the population aged 75 years or more, the proportions of prevalent cases were 20% in males and 13% in females, 11% between 60 and 74 years of age in both sexes. Nearly 600,000 Italian women were alive after a breast cancer diagnosis (41% of all women with this neoplasm), followed by women with cancers of the colon rectum (12%), corpus uteri (7%), and thyroid (6%). In men, 26% of prevalent cases (295,624) were patients with prostate cancer, 16% with either bladder or colon rectum cancer. The projections for 1.1.2015 are of three million (3,036,741) people alive after a cancer diagnosis, 4.9% of the Italian population; with a 20% increase for males and 15% for females, compared to 2010. The cure fractions were heterogeneous according to cancer type and age. Estimates obtained as the sum of cure fractions for all cancer types showed that more than 60% of patients diagnosed below the age of 45 years will reach the same mortality rate of the general population. This proportion decreased with increasing age and it was30% for cancer diagnosed after the age of 74 years. It was observed that 60% of all prevalent cases (1,543,531 people or 2.6% of overall Italian population) had been diagnosed5 years earlier (long-term survivors). Time to cure (5-year CRS95%) was reached in10 years by patients with cancers of the stomach, colon rectum, pancreas, corpus and cervix uteri, brain, and Hodgkin lymphoma. Mortality rates similar to the ones reported by the general population were reached after approximately 20 years for breast and prostate cancer patients. Five-year CRS remained95% for25 years after cancer diagnosis in patients with liver and larynx cancers, non-Hodgkin lymphoma, myeloma, and leukaemia. Time to cure was reached by 27% (20% in men and 33% in women) of all people living after a cancer diagnosis, defined as already cured.The study showed a steady increase over time (nearly +3% per year) of prevalent cases in Italy. A quarter of Italian cancer patients alive in 2010 can be considered as already cured. The AIRTUM Report 2014 describes characteristics of cancer patients and former-patients for 50 cancer types or combinations by sex and age. This detailed information promotes the conduction of studies aimed at expanding the current knowledge on the quality of life of these patients during and after the active phase of treatments (prevalence according to health status), on the long-term effects of treatments (in particular for paediatric patients), on the cost profile of cancer patients, and on rare tumours. All these observations have a high potential impact on health planning, clinical practice, and, most of all, patients' perspective.

Published
2014

25. In 2014 cancer registration covers more than half of the Italian population [Nel 2014 la registrazione dei tumori in Italia è estesa a oltre la metà del Paese]

Author

Crocetti, E, Madeddu, A, Mangone, L, AIRTUM Working Group: : Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Cusimano, R, Dei Tos, A, Falcini, F, Ferretti, S: Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Magoni, M, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G: Tisano, F, Traina, A, Tumino, R, Usala, M, VITALE, Francesco, Vitarelli, S, Zanetti, R., Crocetti, E, Madeddu, A, Mangone, L, AIRTUM Working Group: : Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Cusimano, R, Dei Tos, A, Falcini, F, Ferretti, S: Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Magoni, M, Marchesi, C:, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G: Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
cancer incidence, Italian population, cancer registration, Settore MED/42 - Igiene Generale E Applicata
Published
2014

26. [Hodgkin lymphoma in Italian children and adolescents]

Author

Dal Maso, Luigino, Terracini, Benedetto, Mosso, MARIA LUISA, Buzzoni, Carlotta, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos AP, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Aged, 80 and over, Adult, Male, Adolescent, Incidence, Infant, Newborn, Infant, Middle Aged, Newborn, Prognosis, Hodgkin Disease, Survival Rate, Age Distribution, Italy, Risk Factors, Child, Preschool, 80 and over, Humans, Female, Aged, Child, Retrospective Studies, Sex Distribution, Preschool
Published
2016

27. AIRTUM - Italia 2015: 3 milioni di italiani vivono dopo una diagnosi di tumore, ma incidenza e mortalità sono in calo

Author

Dal Maso, Luigino, Buzzoni, Carlotta, Guzzinati, Stefano, Crocetti, Emanuele, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, Silvia, Fusco, Marco, Gennaro, V, Giacomin, A, Gola, GIAN LUIGI, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, Alessandro, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, Paola, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Adult, Male, Epidemiology, Incidence, Environmental and Occupational Health, Middle Aged, Aged, Disease-Free Survival, Female, Humans, Italy, Neoplasms, Registries, Risk Factors, Sex Distribution, Survival Rate, Public Health, Environmental and Occupational Health, Public Health
Published
2016

28. ITALIAN CANCER FIGURES - REPORT 2015: The burden of rare cancers in Italy = I TUMORI IN ITALIA - RAPPORTO 2015: I tumori rari in Italia

Author

Busco, Susanna, Buzzoni, Carlotta, Mallone, Sandra, Trama, Annalisa, Castaing, Marine, Bella, Francesca, Amodio, Rosalba, Bizzoco, Sabrina, Cassetti, Tiziana, Cirilli, Claudia, Cusimano, Rosanna, De Angelis, Roberta, Fusco, Mario, Gatta, Gemma, Gennaro, Valerio, Giacomin, Adriano, Giorgi Rossi, Paolo, Mangone, Lucia, Mannino, Salvatore, Rossi, Silvia, Pierannunzio, Daniela, Tavilla, Andrea, Tognazzo, Sandro, Tumino, Rosario, Vicentini, Massimo, Vitale, Maria Francesca, Crocetti, Emanuele, Dal Maso, Luigino, Mazzoleni, G, Bulatko, A, Devigili, E, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Vittadello, F, Coviello, V, Cuccaro, F, Calabrese, A, Pinto, A, Cannone, G, Vitali, Me, Sampietro, G, Ghisleni, S, Giavazzi, L, Zanchi, A, Zucchi, A, Giacomin, A, Vercellino, Pc, Andreone, S, Fedele, M, Barale, A, Germinetti, F, Magoni, M, Zani, G, Salvi, O, Puleio, M, Gerevini, C, Adorni, A, Chiesa, R, Lonati, F, Tumino, R, Cascone, G, Frasca, G, Giurdanella, Mc, Martorana, C, Morana, G, Nicita, C, Rollo, Pc, Ruggeri, Mg, Spata, E, Vacirca, S, Sciacca, S, Sciacchitano, C, Fidelbo, M, Paderni, F, Benedetto, G, Vasquez, E, Bella, F, Calabretta, L, Castaing, M, Di Prima, A, Ieni, A, Leone, A, Pesce, P, Sciacchitano, S, Torrisi, A, Varvarà, M, Sutera Sardo, A, Mazzei, A, Lavecchia, Am, Mancuso, P, Nocera, V, Gola, G, Corti, M, Grandi, L, Caparelli, M, Mannino, S, Belluardo, C, Bizzoco, S, Davini, C, Lucchi, S, Villa, M, Anghinoni, E, Di Norcia, R, Ferretti, S, Biavati, P, Marzola, L, Migliari, E, Carletti, N, Petrucci, C, Brosio, F, Piccinni, L, Valente, N, Barchielli, A, Buzzoni, C, Caldarella, A, Corbinelli, A, Di Dia PP, Intrieri, T, Manneschi, G, Nemcova, L, Susini, N, Visoli, C, Zappa, M, Serraino, D, Angelin, T, Bidoli, E, Birri, S, Dal Maso, L, De Dottori, M, De Santis, E, Forgiarini, O, Zucchetto, A, Zanier, L, Filiberti, Ra, Casella, C, Marani, E, Puppo, A, Celesia, Mv, Cogno, R, Garrone, E, Pannozzo, F, Busco, S, Rashid, I, Ramazzotti, V, Cercato, Mc, Natali, M, Battisti, W, Sperduti, I, Macci, L, Bugliarello, E, Bernazza, E, Tamburo, L, Rossi, M, Curatella, S, Tamburrino, S, Fattoruso, S, Valerio, O, Melcarne, A, Quarta, F, Golizia, Mg, Raho, Am, De Maria, V, Vitarelli, S, Ricci, P, Guarda, L, Gatti, L, Pironi, V, Pasolini, A, Bordini, M, Autelitano, M, Ghilardi, S, Leone, R, Filipazzi, L, Bonini, A, Giubelli, C, Russo, Ag, Quattrocchi, M, Distefano, R, Panciroli, E, Bellini, A, Pinon, M, Spinosa, S, Spagnoli, G, Goldoni, Ca, Valla, K, Braghiroli, B, Cirilli, C, Donini, M, Amendola, V, Cavalieri d'Oro, L, Rognoni, M, Le Rose, L, Merlo, E, Negrino, L, Pezzuto, L, Fusco, M, Bellatalla, C, Panico, M, Perrotta, C, Vassante, B, Vitale, Mf, Usala, M, Pala, F, Sini, Gm, Pintori, N, Canu, L, Demurtas, G, Doa, N, Vitale, F, Cusimano, R, Traina, A, Guttadauro, A, Cascio, Ma, Mannino, R, Ravazzolo, B, Brucculeri, Ma, Rudisi, G, Adamo, Ms, Amodio, R, Costa, A, Zarcone, M, Sunseri, R, Bucalo, G, Trapani, C, Staiti, R, Michiara, M, Bozzani, F, Sgargi, P, Borciani, E, Seghini, P, Faccini, F, Prazzoli, R, Mangone, L, Di Felice, E, Pezzarossi, A, Caroli, S, Sacchettini, C, Ferrari, F, Roncaglia, F, Vicentini, M, Falcini, F, Colamartini, A, Bucchi, L, Balducci, C, Ravegnani, M, Vitali, B, Cordaro, C, Caprara, L, Giuliani, O, Giorgetti, S, Palumbo, M, Vattiato, R, Ravaioli, A, Mancini, S, Caiazzo, Al, Cavallo, R, Colavolpe, Af, D'Alessandro, A, Iannelli, A, Lombardo, C, Senatore, G, Sensi, F, Cesaraccio, R, Sechi, O, Pirino, D, Mura, F, Contrino, Ml, Madeddu, A, Tisano, F, Muni, A, Dinaro, Y, Mizzi, M, Sacco, G, Aletta, P, Ziino, Ac, Maspero, S, Fanetti, Ac, Moroni, E, Cometti, I, Annulli, Ml, Cecconami, L, Minerba, S, Minicuzzi, A, Zanetti, R, Rosso, S, Patriarca, S, Prandi, R, Sobrato, I, Gilardi, F, Busso, P, Sacchetto, L, Candela, G, Scuderi, T, Crapanzano, G, Taranto, V, Piffer, S, Gentilini, Ma, Rizzello, R, Cappelletti, M, Stracci, F, D'Alò, D, Scheibel, M, Costarelli, D, Spano, F, Rossini, S, Santucci, C, Petrinelli, Am, Solimene, C, Bianconi, F, Brunori, V, Tagliabue, G, Contiero, P, Tittarelli, A, Fabiano, S, Maghini, A, Codazzi, T, Frassoldi, E, Gada, D, di Grazia, L, Ruzza, Mr, Dei Tos AP, Baracco, M, Baracco, S, Bovo, E, Dal Cin, A, Fiore, Ar, Greco, A, Guzzinati, S, Monetti, D, Rosano, A, Stocco, C, Tognazzo, S, Zorzi, M, Merletti, F, Magnani, C, Pastore, G, Terracini, B, Alessi, D, Cena, T, Lazzarato, F, Macerata, V, Maule, M, Mosso, Ml, Sacerdote, C, Cocchioni, M, Pascucci, C, Ponz de Leon, M, Domati, F, Rossi, G, Kaleci, S, Rossi, F, Benatti, P, Roncucci, L, Di Gregorio, C, Magnani, G, Pedroni, M, Maffei, S, Mariani, F, Reggiani-Bonetti, L, Gennaro, V, Benfatto, L, Lando, C, Mazzucco, G, Romanelli, A, Storchi, C, Sala, O, Gabbi, C, and Buzzoni, C.

Published
2016

30. [Cancer survival in Italy in 2000-2007 is better than in Europe]

Author

Buzzoni, Carlotta, Crocetti, Emanuele, De Angelis, Roberta, Dal Maso, Luigino, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Adult, Europe, Male, Survival Rate, Italy, Neoplasms, Female, Humans, Registries, Retrospective Studies
Published
2015

31. [AIRTUM and SIE for a shared definition of haemolymphopoietic cancers]

Author

Torrisi, Antonina, Castaing, Marine, Giacomin, Adriano, Luminari, Stefano, Mangone, Lucia, Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, AIRTUM Working Group, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Societies, Scientific, Italy, Risk Factors, Humans, Population Surveillance, Public Health, Registries, Risk Assessment, Sicily, Hematologic Neoplasms, Scientific, Societies
Published
2015

32. Trends in Lung Cancer and Smoking Behavior in Italy: An Alarm Bell for Women

Author

Trama, Annalisa, Boffi, Roberto, Contiero, Paolo, Buzzoni, Carlotta, Pacifici, Roberta, Mangone, Lucia, Coviello, V, Buzzoni, C, Fusco, M, Barchielli, A, Cuccaro, F, De Angelis, R, Giacomin, A, Luminari, S, Randi, G, Mangone, L, Mazzoleni, G, Bulatko, A, Devigili, E, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Vittadello, F, Coviello, V, Cuccaro, F, Calabrese, A, Pinto, A, Cannone, G, Vitali, ME, Galasso, R, Del Riccio, L, Napolitano, D, Sampietro, G, Ghisleni, S, Giavazzi, L, Zanchi, A, Zucchi, A, Giacomin, A, Vercellino, PC, Andreone, S, Fedele, M, Barale, A, Germinetti, F, Magoni, M, Salvi, O, Puleio, M, Gerevini, C, Chiesa, R, Lonati, F, Cavalieri d'Oro, L, Rognoni, M, Le Rose, L, Merlo, E, Bracchi, A, Negrino, L, Pezzuto, L, Ardizzone, A, Spagnolo, G, Cozzi, E, De Lorenzism, L, Lotti, F, Pagliara, MC, D'Argenzio, A, D'Abronzo, M, De Francesco, D, Pereira da Silva, MCM, Menditto, V, Perrotta, E, Pesce, MT, Sessa, A, Sciacca, S, Sciacchitano, S, Fidelbo, M, Benedetto, G, Benedetto, A, Calabretta, LMR, Caruso, AM, Castaing, M, Di Prima, AA, Dinaro, YM, Fidelbo, P, Grosso, G, Ippolito, A, Irato, E, Leone, A, Paderni, F, Pesce, PNR, Pollina Addario, S, Savasta, A, Sciacchitano, CG, Torrisi, AAM, Torrisi, A, Varvarà, M, Viscosi, C, Sutera Sardo, A, Sia, A, Scalzi, S, Lavecchia, AM, Mancuso, P, Nocera, V, Mancusi, F, Del Duca, S, Gola, G, Corti, M, Caparelli, M, Ferretti, S, Marzola, L, Migliari, E, Carletti, N, Biavati, P, Petrucci, C, Serraino, D, Angelin, T, Bidoli, E, Birri, S, Dal Maso, L, De Dottori, M, De Santis, E, Forgiarini, O, Zucchetto, A, Zanier, L, Pannozzo, F, Busco, S, Rossi, M, Curatella, S, Bugliarello, E, Macci, L, Bernazza, E, Calabretta, F, Tamburrino, S, Sperduti, I, Tamburo, L, Serafini, G, Quarta, F, Melcarne, A, Golizia, MG, Arciprete, C, De Maria, V, Filiberti, RA, Casella, C, Marani, E, Puppo, A, Celesia, MV, Cogno, R, Vitarelli, S, Ricci, P, Autelitano, M, Ghilardi, S, Leone, R, Filipazzi, L, Bonini, A, Giubelli, C, Russo, AG, Quattrocchi, M, Distefano, R, Panciroli, E, Bellini, A, Pinon, M, Spinosa, S, Spagnoli, G, Carrozzi, G, Cirilli, C, Valla, K, Amendola, V, Fusco, M, Bellatalla, C, Ciullo, V, Di Buono, M, Fusco, M, Panico, M, Perrotta, C, Vitale, MF, Usala, M, Pala, F, Sini, GM, Pintori, N, Canu, L, Demurtas, G, Doa, N, Vitale, F, Cusimano, R, Traina, A, Guttadauro, A, Cascio, MA, Mannino, R, Ravazzolo, B, Brucculeri, MA, Rudisi, G, Adamo, MS, Amodio, R, Costa, A, Zarcone, M, Sunseri, R, Bucalo, G, Trapani, C, Staiti, R, Michiara, M, Bozzani, F, Sgargi, P, Boschetti, L, Migliazza, S, Reggiani, E, Incardona, N, Borciani, E, Seghini, P, Prazzoli, R, Zanetti, R, Rosso, S, Patriarca, S, Prandi, R, Sobrato, I, Gilardi, F, Busso, P, Sacchetto, L, Tumino, R, Cascone, G, Frasca, G, Giurdanella, MC, Martorana, C, Morana, G, Nicita, C, Rollo, PC, Ruggeri, MG, Spata, E, Vacirca, S, Mangone, L, Vicentini, M, Di Felice, E, Pezzarossi, A, Ferrari, F, Roncaglia, F, Sacchettini, C, Caroli, S, Falcini, F, Colamartini, A, Bucchi, L, Balducci, C, Ravegnani, M, Vitali, B, Cordaro, C, Caprara, L, Giuliani, O, Giorgetti, S, Palumbo, M, Vattiato, R, Ravaioli, A, Mancini, S, Caiazzo, AL, Cavallo, R, Colavolpe, AFG, D'Alessandro, A, Iannelli, A, Lombardo, C, Senatore, G, Sensi, F, Cesaraccio, R, Pirino, D, Mura, F, Contrino, ML, Madeddu, A, Tisano, F, Dinaro, Y, Muni, A, Mizzi, M, Bella, F, Rossitto, L, Sacco, G, Aletta, P, Colanino Ziino, A, Maspero, S, Fanetti, AC, Cometti, I, Cecconami, L, Minerba, S, Mincuzzi, A, Carone, S, Tanzarella, M, Galluzzo, C, Barchielli, A, Buzzoni, C, Caldarella, A, Corbinelli, A, Intrieri, T, Di Dia, PP, Manneschi, G, Nemcova, L, Visioli, C, Zappa, M, Candela, G, Scuderi, T, Crapanzano, G, Taranto, V, Piffer, S, Gentilini, M, Rizzello, R, Bombarda, L, Pedron, M, Clivati, E, Stracci, F, D'Alò, D, Scheibel, M, Costarelli, D, Spano, F, Rossini, S, Santucci, C, Petrinelli, AM, Solimene, C, Bianconi, F, Brunori, V, Tagliabue, G, Contiero, P, Tittarelli, A, Fabiano, S, Maghini, A, Codazzi, T, Barigelletti, G, D'Agostino, A, Modonesi, C, Rugge, M, Baracco, M, Baracco, S, Bovo, E, Dal Cin, A, Fiore, AR, Greco, A, Guzzinati, S, Martin, G, Memo, L, Monetti, D, Rizzato, S, Rosano, A, Stocco, C, Tognazzo, S, Zorzi, M, Brustolin, A, Beggiato, S, Aniceti, S, Fiocchetti, L, Schirra, G, Galeotti, P, Capati, A, Nami, A, Montanaro, M, Verrico, G, Poleggi, F, Rashid, I, Grappasonni, I, Pascucci, C, Merletti, F, Magnani, C, Pastore, G, Terracini, B, Alessi, D, Cena, T, Lazzarato, F, Macerata, V, Maule, M, Mosso, ML, Sacerdote, C, Romanelli, A, Mangone, L, Storchi, C, Sala, O, Gabbi, C, Gennaro, V, Benfatto, L, Malacarne, D, Lando, C, Campi, MG, Mazzucco, G, Ponz de Leon, M, Domati, F, Rossi, G, Goldoni, CA, Kaleci, S, Rossi, F, Benatti, P, Roncucci, L, Di Gregorio, C, Magnani, G, Pedroni, M, Maffei, S, Mariani, F, Reggiani-Bonetti, L, Sassatelli, R, Cassetti, T, Giorgi Rossi, P, and Vicentini, M

Abstract

Introduction The epidemiology of lung cancer is changing worldwide, with smoking being the key driver of lung cancer incidence and mortality. Our aim is to analyze the incidence, survival and mortality trends in Italy in the framework of the 2017 survey on smoking behavior in Italy.Methods AIRTUM 2017 reports on cancer survival and incidence; 2017 survey on smoking behavior in Italy.Results Men achieved progress in lung cancer control characterized by a decrease in incidence and mortality and an increase in survival. The decreasing use of tobacco in men (from 60% in the 1960s to 24% in 2017) was most likely responsible for the decreasing incidence and mortality. Women showed no progress: although survival improved slightly, the incidence and mortality were both on the rise. This was most likely due to the increasing smoking rates in women in the 1970s and 80s. Of major concern is the accelerated rise in the number of smoking women from 4.6 million in 2016 to 5.7 million in 2017 compared to the decrease observed in men (from 6.9 to 6 million).Conclusions The incidence and mortality trends in males clearly demonstrate that primary prevention is the most effective way to reduce lung cancer mortality. By contrast, a 24% increase in the prevalence of smoking among women in just 1 year is extremely worrying for the future, and calls for immediate action by targeted strategies to reduce tobacco consumption in women and avert the dreadful prospect of a lung cancer epidemic in Italy.

Published
2017
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33. Methods of data processing for debris flow seismic warning

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental, Universitat Politècnica de Catalunya. EnGeoModels - Monitoring and Modelling in Engineering Geology, Arattano, Massimo, Coviello, V, Abanco Martínez de Arenzana, Claudia, Hurlimann Ziegler, Marcel, McArdell, Brian, W, Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental, Universitat Politècnica de Catalunya. EnGeoModels - Monitoring and Modelling in Engineering Geology, Arattano, Massimo, Coviello, V, Abanco Martínez de Arenzana, Claudia, Hurlimann Ziegler, Marcel, and McArdell, Brian, W

Abstract

The output of the seismic devices commonly employed for the monitoring of debris flows, such as geophones and seismometers, is a voltage that is directly proportional to the ground vibration velocity. The output signal in analogical form is usually digitalized at a fixed sampling frequency to be opportunely processed. The processing is performed to both reduce the amount of data to be stored in a data-logger and to reveal the main features of the phenomenon that are not immediately detectable in the raw signal, such as its main front, eventual subsequent surges, the wave form and so on. The processing also allows a better and sounder development of algorithms, when seismic devices are employed for warning purposes. However, the processing of the raw signal alters in different ways the original raw data, depending on the processing method adopted. This may consequently limit or reduce the efficacy of the warning. Different methods of data processing can be found in literature, each with its own advantages and shortcomings. In this paper we will explore and discuss the effects of some of these latter on the efficacy of the algorithms employed for warning, applying them to the seismic recordings obtained in the instrumented basins of Gadria (Italy), Rebaixader (Spain) and Illgraben (Switzerland)., Peer Reviewed, Postprint (published version)

Published
2016

34. High elevation rock falls and their climatic control: a case study in the Conca di Cervinia (NW Italian Alps)

Author

Chiarle M. (1), Coviello V. (1), Arattano M. (1), Silvestri P. (1, and Nigrelli G. (1)

Subjects
Climate, High-elevation rock walls, Italian Alps, Stability
Abstract

One of the impacts of climate warming in recent years is the evident increase of the number of rock fall occurrences at high elevations. With few exceptions, these events have small magnitudes and thus are rarely reported and documented, even less so in the past. Therefore it is difficult to use a statistical approach to analyze of the relationships between climate warming and rock slope instability. On the other hand, it is often difficult to carry out a time analysis of meteorological conditions responsible for rock fall triggering, considering that very few automatic weather stations (AWS) are located in the areas and in the altitudinal range that are affected by cryosphere degradation (i.e. above c.a. 3,000 m elevation in the Alps), and that climatic conditions in high elevation environments are spatially and temporally variable. The present study addresses the above-mentioned issues through analysis of a series of small rock falls that occurred in the last 10 years on the Matterhorn and surrounding rock slopes. A specific focus is temperature: we present a preliminary analysis of the spatial and seasonal variability of the vertical temperature gradient in the Conca di Cervinia, where the Matterhorn is located, to illustrate the uncertainty in estimates of the thermometric conditions at high elevation rock fall sites.

Published
2014

35. Confronto fra registri specializzati e registri tumori di popolazione: i risultati del progetto ReNaM-AIRTUM = A comparative analysis between regional mesothelioma registries and cancer registries: results of the ReNaM-AIRTUM project

Author

Nicita, C, Buzzoni, C, Chellini, E, Ferretti, S, Marinaccio, A, Mensi, C, AIRTUM Working Group, ReNaM Working Group, Progetto ReNaM AIRTUM Working Group, Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Candela, G, Cavalieri D’oro, L, Cocchioni, Mario, Coviello, V, Cremone, L, Crocetti, E, Cusimano, R, Dei Tos AP, Falcini, F, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, Susanna, Zanetti, R, and Progetto ReNaM AIRTUM Working

Published
2014

36. Characterization of large mass movements occurred in the Italian Alps using seismic monitoring networks

Author

Coviello V. (1), De Santis F. (1, Chiarle M. (1), Arattano M. (1), and Godio A. (2)

Abstract

Passive seismic monitoring techniques have been profusely adopted to detect seismic sources induced by slope deformation and landslide propagation. Seismic signal processing can provide relevant information on the dynamics of unstable slopes, and may allow the identification of collapse precursors. Otherwise, seismic sensors have been used to characterize the volume and propagation velocity of rock-slides and debris-flows. For these purposes, geophone arrays are usually installed in specific monitoring sites. However, also a broadband seismic network can be used to identify signals originated by the detachment and movements of large masses. One advantage of using these networks would be the ability to detect remote events that might otherwise go unnoticed for weeks or months. Furthermore, even if often recorded at a distance, the spectral analysis of the low frequency content of the recorded signal may allow a preliminary characterization of the phenomenon. We selected five well known large mass movements occurred in the Italian Alps with volumes between 300.000 cubic meter (Monte Rosa rock avalanche, 2007) and 34.000.000 cubic meter (Val Pola rock avalanche, 1987). On average, seismic stations located up to 40 km far from these events were able to detect them, except for the Val Pola rock avalanche which was recorded at a distance greater than 100 km. As already observed by other authors, for these phenomena common signal characteristics include emergent onsets on all channels, slowly decaying tails and a triangular spectrogram shape. For this study we used different ground velocity sensors and considering the event magnitude, the distance source-receiver and to ensure a flat frequency response we focused on the 1-40 Hz frequency band. In this work these five large slope instabilities are described and the associated seismograms are presented and analyzed together with a first discussion of their spectral characteristics.

Published
2014

39. Debris flow monitoring at Mardarello catchment, Italian Western Alps

Author

Turconi L., Arattano M., Coviello V., and Savio G.

Abstract

In this work we report latest outcomes of 18 years-long dataset of monitoring in a very active debris flow-producing catchment, left tributary of the Cenischia valley, NW Italian Alps. The Mardarello catchment (6.61 km²), due to very unfavourable geological and geomorphologic conditions, can be considered a perennial source of debris (the bulk can be estimated at 2.6 106 m3) containing even large-sized blocks. It is incised in carbonatic, massive Mesozoic rocks ("Calcescisti con Pietre Verdi"), interbedded with clayey-arenitic schist, very steeply dipping downslope and widely overlied by deep-seated slope collapse deposits and partly by detrital talus. A north-south oriented fault system together with minor failures has resulted in a complex network of rock joints and cracks. The vegetal cover is developed down 2400 m elevation with pasture herbs and sparse shrubs. Around 2000 m a.s.l. Swiss mountain pine and Larix decidua partly colonize unstable slopes, below such altitude other kinds of Conifers are widely spread all over the catchment, still below chestnuts are also present; such biotopes are in part inherited from re-forestation works carried on for decades by the National Forestry Corps to hinder the soil degradation. The high drop between maximum basin altitude (Rocciamelone Mt., 3538 m a.s.l.) and the fan apex (900 m a.s.l.) is quickly attained over a stretch of only 4 km, with an average slope gradient of 60% and maximum of 80%. The average annual precipitation equals to 820 mm, monthly rainfall depth is highest in Autumn and Springtime, accounting as a whole for 62% of the yearly total. A 1-3 m thick snow mantle usually caps the slopes above 2500 m a.s.l. from half October to the end of June. In spite of reforestation and hydraulic works realized in recent years, debris flows (2-years return period between 1991-2011) still pose significant hazard to human settlements located downstream. In the last one hundred years, thanks to historical documents andon-site monitoring conducted by the CNR-IRPI 31 debris flow events which caused significant damages have been reported. Generally, the mass transport is dominated by channelized debris flow occurring during the summer season, without damages for settlements; nevertheless, major events in the past impacted on the national road at the valley bottom. Since July 1994 the Marderello catchment had been instrumented for a best knowledge of the triggering factors, debris flow dynamics and related effects, in such a severe mountain environment, also in the sight to suggest possible structural interventions for preventing or reducing future damage in the underlying Novalesa village and ensure safety to hundreds of resident and floating population (Tropeano et al., 1996). The rainfall monitoring network consists of four raingauges placed at different elevations, between 800 and 2854 m a.s.l.; others meteorological data (air moisture and temperature, atmospheric pressure, wind speed and direction) are provided by three MICROS® radio-transmitting stations located at 3150, 2150 and 830 m a.s.l.. In 2013 the monitoring system has been further improved and extended on the alluvial fan with the installation of one ultrasonic device and four geophones (at a distance of around 50 m reciprocally) in order to detect debris flow wave-fronts depth and time-to-arrival. To reduce the amount of recorded data, the original ground velocity signal measured by the geophones is transformed into a mean value of amplitude of the velocity signal second per second (Arattano, 1999). The research presently focuses on: (i) the investigation of rainfall characteristics, as recorded to different catchment elevations, in the sight to detect rainfall triggering values for debris flow initiation (Turconi et al., 2008); (ii) the collection of debris-flow seismic data for the future development of a warning system for the lowest part of the alluvial fan. References. Arattano, M. (1999). On the use of seismic detectors as monitoring and warning systems for debris flows. Nat. Hazards, 20, 197-213. Tropeano D., Casagrande A., Luino F., Cescon F. (1996). Processi di mud-debris flow in Val Cenischia (Alpi Graie). Osservazioni nel bacino del T. Marderello. Quaderno di studi e di documentazione n°20 - Suppl. a GEAM Anno XXXIII, n. 2-3. Turconi L., Kumar De S., Tropeano D., Savio G. (2010). Slope failure and related processes in the Mt. Rocciamelone area (Cenischia Valley, Western Italian Alps), Geomorphology, Volume 114, Issue 3, 115-128.

Published
2013

45. The Aiguille du Midi (Mont Blanc massif): a unique high-Alpine site to study bedrock permafrost

Author

Deline, Philip, Bölhert, R., Coviello, V., Cremonese, E., Gruber, S., Krautblatter, M., Jaillet, Stéphane, Malet, Emmanuel, Morra Di Cella, U., Noetzli, J., Pogliotti, P., Rabatel, Antoine, Ravanel, Ludovic, Sadier, Benjamin, Verleysdonk, S., Environnements, Dynamiques et Territoires de la Montagne (EDYTEM), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Ecologie des Hydrosystèmes Fluviaux (EHF), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Glaciology, Geomorphodynamics & Geochronology, Laboratoire de glaciologie et géophysique de l'environnement (LGGE), Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), and Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])

Subjects
[SDE.MCG]Environmental Sciences/Global Changes, ComputingMethodologies_GENERAL
Abstract

EGU2009-9220

Published
2010

46. Conceptual design and first results of a combined electrical resistivity and induced polarization monitoring at the Aiguille du Midi rock permafrost summit (Mont Blanc Massif, French/Italian Alps)

Author

Krautblatter, M., Verleysdonk, S., Flores-Orozco, A., Kemna, A., Deline, Philip, Ravanel, Ludovic, Pogliotti, P., Coviello, V., Malet, Emmanuel, Agrosphere (ICG 4), Agrosphere, Environnements, Dynamiques et Territoires de la Montagne (EDYTEM), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Ecologie des Hydrosystèmes Fluviaux (EHF), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDE.MCG]Environmental Sciences/Global Changes
Abstract

EGU2009-9215

Published
2009

47. L'Aiguille du Midi (massif du Mont Blanc) : un site remarquable pour l'étude du permafrost des parois d'altitude

Author

Deline, Philip, Bölhert, R., Coviello, V., Cremonese, E., Gruber, S., Krautblatter, M., Jaillet, Stéphane, Malet, Emmanuel, Morra Di Cella, U., Noetzli, J., Pogliotti, P., Rabatel, Antoine, Ravanel, Ludovic, Sadier, Benjamin, Verleysdonk, S., Environnements, Dynamiques et Territoires de la Montagne (EDYTEM), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Glaciology, and Geomorphodynamics & Geochronology

Subjects
[SDE.MCG]Environmental Sciences/Global Changes
Published
2009

49. Early-stage diffuse large B-cell lymphoma of the submental region: a case report and review of the literature.

Author

Patini, R., Coviello, V., Riminucci, M., Corsi, A., and Cicconetti, A.

Subjects
SUBMENTAL triangle, PATIENT management, HISTOPATHOLOGY, NECK tumors
Abstract

Lymphomas represent the third most common group of malignant lesions in the oral cavity and maxillofacial region, following squamous cell carcinoma and salivary gland neoplasm. Traditionally, lymphomas are divided into two subtypes, Hodgkin lymphomas ( HL) and non-Hodgkin lymphomas ( NHL). The diffuse large B-cell lymphoma ( DLBCL) is a rapidly aggressive NHL constituted by big lymphoid cells that can appear as a nodal or extra-nodal disease; about 4% of DLBCL are initially confined to extra-nodal sites. The oral and maxillofacial region is the second most common extra-nodal site, and half of the cases are located in Waldeyer's ring. The tumour may present clinical symptoms and radiographic findings as local swelling, pain or discomfort, ulcer and bone resorption mimicking other pathologic lesions such as periodontal disease, pericoronitis, apical radiolucencies or dental abscesses. We report a case of a patient with DLBCL of the submental region staged at I AE according to the Ann Arbor lymphoma staging system. [ABSTRACT FROM AUTHOR]

Published
2017
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50. Platelet-rich plasma improves wound healing in multiple myeloma bisphosphonate-associated osteonecrosis of the jaw patients

Author

Coviello, V, Peluso, F, Dehkhargani, S, Verdugo, F, Raffaelli, Luca, Manicone, Paolo Francesco, D'Addona, Antonio, Raffaelli, Luca (ORCID:0000-0003-4525-8446), Manicone, Paolo Francesco (ORCID:0000-0003-0283-2903), D'Addona, Antonio (ORCID:0000-0002-0876-7594), Coviello, V, Peluso, F, Dehkhargani, S, Verdugo, F, Raffaelli, Luca, Manicone, Paolo Francesco, D'Addona, Antonio, Raffaelli, Luca (ORCID:0000-0003-4525-8446), Manicone, Paolo Francesco (ORCID:0000-0003-0283-2903), and D'Addona, Antonio (ORCID:0000-0002-0876-7594)

Abstract

Bisphosphonates are drugs used to treat various metabolic and malignant bone diseases. In the past 10 years intravenous bisphosphonates have been associated with increased risk of osteonecrosis of the jaw (ONJ). The aim of the present study is to evaluate platelet-rich plasma (PRP) wound healing benefits in multiple myeloma (MM) patients who developed ONJ after surgical tooth extraction. The study included 7 patients, 2 males and 5 females. All individuals had been taking zoledronate or pamidronate followed by zoledronate for an average of 5 years. Four subjects had only standard surgical debridement and sequestrectomy to treat the ONJ and three had additional autologous PRP. The patients were followed-up for 3 months. The use of PRP to enhance wound healing and reduce bone exposure seems to be a good treatment protocol in ONJ MM subjects.

Published
2012

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