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114 results on '"Coverlizza S"'

4. Atypical Urinary Citology in Kidney Transplant Recipients

Author

Massara, C, primary, Basolo, B, additional, Funaro, L, additional, Bayle, F., additional, De Marchi, A., additional, Formica, M, additional, Guermani, P, additional, Rollino, C, additional, Segoloni, G P, additional, Coverlizza, S, additional, and Piccoli, G, additional

Published
1996
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42. Balloon cell melanoma: a report of two cases.

Author

Aloi, F. G., Coverlizza, S., and Pippione, M.

Subjects
*MELANOMA, *SKIN disease diagnosis, *PRECANCEROUS conditions, *PIGMENTATION disorders, *IMMUNOHISTOCHEMISTRY, *DIFFERENTIAL diagnosis
Abstract

Two cases of balloon cell malignant melanoma of the skin are reported. The first lesion was pigmented, the second was amelanotic. Histologically the tumor mass was dermal and intraepidennal and almost exclusively composed of balloon cells. Many of the clear cells demonstrated positivity with tile S-IOU protein immunostaining. the problems of clear-cell tumor differential diagnosis are discussed. [ABSTRACT FROM AUTHOR]

Published
1988
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45. Clinico--Pathological Features of Collagenous Colitis: Case Report and Literature Review.

Author

Coverlizza, S., Ferrari, A., Scevola, F., Gemme, C., Cavallero, M., Spandre, M., Risio, M., and Rossini, F. P.

Subjects
COLITIS, DIARRHEA, ABDOMINAL pain, COLLAGEN, GASTROINTESTINAL mucosa, DISEASE relapse
Abstract

Collagenous colitis is a newly identified condition, with clinical features of chronic watery diarrhea and abdominal pain. Histologically the main characteristic is the presence of a thick collagen band below the surface epithelium. Collagenous colitis occurs in adults, especially women. Endoscopy reveals no particular changes in the intestinal mucosa. Symptoms may persist for years with periods of remission and recurring acute attacks. The cause of this condition is still unknown, and because of no real knowledge only symptoms can be treated, usually with little success. [ABSTRACT FROM AUTHOR]

Published
1986

47. Immunohistochemical study of epithelial cell proliferation in hyperplastic polyps, adenomas, and adenocarcinomas of the large bowel

Author

Risio, M., Coverlizza, S., Ferrari, A., Candelaresi, G.L., and Rossini, F.P.

Abstract

A monoclonal antibody to bromodeoxyuridine was used in tissue specimens previously incubated with bromodeoxyuridine to show S-phase cells by immunohistochemical technique. Biopsy specimens of normal mucosa (n = 10), hyperplastic polyps (n = 10), adenomas with low-grade dysplasia (n = 20), adenomas with high-grade dysplasia (n = 10), and invasive adenocarcinomas (n = 10) of the large bowel were studied. Labeling index and cell proliferative patterns were analyzed. No statistically significant difference was found in labeling index between normal mucosa and hyperplastic polyps or between adenomas with high-grade dysplasia and adenocarcinomas. The labeling index was significantly lower in normal mucosa and in hyperplastic polyps than in adenomas and adenocarcinomas (p < 0.001). The difference in labeling index between adenomas with high-grade dysplasia and low-grade dysplasia was also statistically significant (0.01 < p < 0.05). In normal mucosa and in hyperplastic polyps the proliferative zone was confined to the lower two-thirds of the crypt; no kinetic activity was found in the upper portions of the crypt or in surface epithelium. In adenomas the labeled cells were either present in the upper third or scattered along the whole axis of the crypt and in the surface epithelium. Labeling patterns in invasive carcinomas were similar to those observed in adenomas with high-grade dysplasia. The difference in proliferative patterns between hyperplastic polyps and adenomas supports a different significance of the two polypoid lesions in the histogenesis of large bowel cancer; our results confirm the subsequent steps of the adenoma-carcinoma sequence. Immunohistochemical labeling patterns observed with monoclonal antibody to bromodeoxyuridine in polypoid and cancer lesions of the large bowel are similar to those described by autoradiographic studies.

Published
1988
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50. Tumor Staging But Not Grading Is Associated With Adverse Clinical Outcome in Neuroendocrine Tumors of the Appendix

Author

Cristina Fava, Sofia Asioli, Alfredo Berruti, Alberto Comino, Paolo De Giuli, Paola Cassoni, Lorenzo Daniele, Sergio Coverlizza, Mauro Papotti, Marco Volante, Claudia Manini, Volante M, Daniele L, Asioli S, Cassoni P, Comino A, Coverlizza S, De Giuli P, Fava C, Manini C, Berruti A, and Papotti M

Subjects
carcinoid, Adult, Male, Oncology, medicine.medical_specialty, Adolescent, Mitosis, Neuroendocrine tumors, appendix, World Health Organization, Pathology and Forensic Medicine, Young Adult, Neuroendocrine tumor, Internal medicine, Carcinoma, Humans, Medicine, Stage (cooking), Child, Survival rate, Grading (tumors), Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, Neoplasm Grading, business.industry, Retrospective cohort study, staging, Middle Aged, Prognosis, medicine.disease, Appendix, Carcinoma, Neuroendocrine, Survival Rate, medicine.anatomical_structure, Appendiceal Neoplasms, Italy, Female, Surgery, prognosis, Anatomy, business, prognosi
Abstract

Appendiceal neuroendocrine neoplasms (NENs) are rare and usually incidentally discovered. Most cases are clinically indolent, although the rare aggressive ones are poorly predictable. The aim of this study was to test the applicability and prognostic significance of the new World Health Organization (WHO) classification and to test the several pathologic features and TNM staging systems (American Joint Committee on Cancer and European Neuroendocrine Tumor Society) in these tumors. A multi-institutional retrospective series of 138 appendiceal NENs was selected on the basis of the availability of both pathologic material and clinical information, including follow-up data. All cases were reviewed to record pathologic features and to apply year 2000 and 2010 WHO classifications, as well as European Neuroendocrine Tumor Society and American Joint Committee on Cancer TNM stages. Clinical and pathologic characteristics were compared with disease outcome by contingency, univariate, and multivariate survival analyses. Although up to one third of cases presented several malignancy-associated pathologic features, only 4 patients died of the disease. Adverse outcome was significantly associated with extramural extension (including mesoappendix), well-differentiated carcinoma diagnosis (2000 WHO classification), pT3-4 stage, older age, and presence of positive resection margins, but not with tumor size, mitotic or proliferative indexes, and, consequently, 2010 WHO grading. In the appendix, at variance with midgut/hindgut NENs, the 2000 WHO classification performs better than the grading-based 2010 WHO scheme and, together with tumor stage, is the most relevant parameter associated with clinical aggressiveness.

Published
2013

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