1. Cellular and molecular regulation of cardiac glucose transport.
- Author
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Young, Lawrence, Coven, David, Russell, Raymond, Young, L H, Coven, D L, and Russell, R R 3rd
- Subjects
HEART metabolism ,GLUCOSE metabolism ,ANIMALS ,BIOLOGICAL transport ,CARRIER proteins ,CELLULAR signal transduction ,CORONARY disease ,MUSCLE proteins - Abstract
Tremendous advances have recently been achieved in our understanding of the cellular and molecular mechanisms regulating glucose transport in the heart and other tissues. An intricate network of signaling molecules and intracellular proteins trigger and mediate the vesicular movement of GLUT vesicles, targeting them to the sarcolemma. Ongoing research in this area promises to further define these mechanisms in the heart, which may lead to potential targets for pharmacologic or gene therapy to modulate glucose transport in the heart. [ABSTRACT FROM AUTHOR]
- Published
- 2000
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