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197 results on '"Couturier, Marc Roger"'

1. Bartonella quintana Infection in Kidney Transplant Recipients from Donor Experiencing Homelessness, United States, 2022

Author

Beeson, Amy M., Rich, Shannan N., Russo, Michael E., Bhatnagar, Julu, Kumar, Rebecca N., Ritter, Jana M., Annambhotla, Pallavi, Takeda, Moe R., Kuhn, Kira F., Pillai, Prishanya, DeLeon- Carnes, Marlene, Scobell, Rebecca, Ekambaram, Maheswari, Finkel, Rachel, Reagan-Steiner, Sarah, Martines, Roosecelis B., Satoskar, Rohit S., Vranic, Gayle M., Mohammed, Raji, Rivera, Gloria E., Cooper, Kumarasen, Abdelal, Heba, Couturier, Marc Roger, Bradley, Benjamin T., Hinckley, Alison F., Koehler, Jane E., Mead, Paul S., Kuehnert, Matthew J., Ackelsberg, Joel, Basavaraju, Sridhar V., and Marx, Grace E.

Subjects
Transplantation of organs, tissues, etc. -- Complications and side effects, Verruga peruana -- Diagnosis -- Care and treatment, Homelessness -- Health aspects, Lice -- Health aspects, Medical screening -- Methods, Health
Abstract

Bartonella quintana is a small, facultatively intracellular, gram-negative bacillus that is transmitted to humans through the feces of an infected human body louse (Pediculus humanus corporis) (1). B. quintana infection [...]

Published
2024

10. Where Have All the Diagnostic Morphological Parasitologists Gone?

Author

Bradbury, Richard S., primary, Sapp, Sarah G. H., additional, Potters, Idzi, additional, Mathison, Blaine A., additional, Frean, John, additional, Mewara, Abhishek, additional, Sheorey, Harsha, additional, Tamarozzi, Francesca, additional, Couturier, Marc Roger, additional, Chiodini, Peter, additional, and Pritt, Bobbi, additional

Published
2022
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18. Proceedings of the Clinical Microbiology Open 2018 and 2019 - a Discussion about Emerging Trends, Challenges, and the Future of Clinical Microbiology

Author

Doern, Christopher D., primary, Miller, Melissa B., additional, Alby, Kevin, additional, Bachman, Michael A., additional, Brecher, Stephen M., additional, Casiano-Colon, Aida, additional, Couturier, Marc Roger, additional, Johnson, J. Kristie, additional, Kirby, James E., additional, McElvania, Erin, additional, Newton, Duane W., additional, Nolte, Frederick S., additional, Pancholi, Preeti, additional, McNult, Peggy, additional, Dharmarha, Vaishali, additional, and Dunbar, Sherry, additional

Published
2022
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22. Evaluation of Three SARS CoV-2 IgG Antibody Assays and Correlation with Neutralizing Antibodies

Author

Rychert, Jenna, Couturier, Marc Roger, Elgort, Marc, Lozier, Bucky Ken, La’ulu, Sonia, Genzen, Jonathan R, Straseski, Joely A, Delgado, Julio C, and Slev, Patricia R

Subjects
Serology, COVID-19 Testing, SARS-CoV-2, Immunoglobulin G, COVID-19, Humans, Antibodies, Neutralizing, Article
Abstract

Background As serologic assays for SARS-CoV-2 become more widely utilized, it is important to understand their performance characteristics and correlation with neutralizing antibodies. We evaluated three commonly used SARS-CoV-2 IgG assays (Abbott, DiaSorin and EUROIMMUN) for clinical sensitivity, specificity, and correlation with neutralizing antibodies and then compared antibody kinetics during the acute phase of infection. Methods Three panels of samples were tested on every assay. Sensitivity was assessed using a panel of 35 specimens serially collected from 7 RT-PCR-confirmed COVID-19 patients. Specificity was determined using 100 sera samples collected in 2018 from healthy individuals prior to the outbreak. Analytical specificity was determined using a panel of 37 samples from individuals with respiratory illnesses other than COVID-19. Results Clinical sensitivity was 91.43% (95% CI 76.94%-98.20%) for Abbott, and 88.57% (95% CI 73.26%-96.80%) for both DiaSorin and EUROIMMUN. Clinical specificity was 99.00% (95% CI 94.55%-99.97%) for Abbott and DiaSorin and 94.00% (95% CI 87.40%-97.77%) for EUROIMMUN. The IgG assays demonstrated good qualitative agreement (minimum of 94%) and good correlation between the quantitative result for each combination of assays (r2≥0.90). The neutralizing antibody response did not necessarily follow the same temporal kinetics as the IgG response and did not necessarily correlate with IgG values. Conclusion The three IgG antibody assays demonstrated comparable performance characteristics. Importantly, a qualitative positive IgG result obtained with any of the assays was associated with the presence of neutralizing antibodies; however, neutralizing antibody concentrations did not correlate well with signal to cutoff ratios.

Published
2020

24. Application, Verification, and Implementation of SARS-CoV-2 Serologic Assays with Emergency Use Authorization

Author

Theel, Elitza S., primary, Couturier, Marc Roger, additional, Filkins, Laura, additional, Palavecino, Elizabeth, additional, Mitchell, Stephanie, additional, Campbell, Sheldon, additional, Pentella, Michael, additional, Butler-Wu, Susan, additional, Jerke, Kurt, additional, Dharmarha, Vaishali, additional, McNult, Peggy, additional, and Schuetz, Audrey N., additional

Published
2020
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38. High Prevalence of Shigella or Enteroinvasive Escherichia coli Carriage among Residents of an Internally Displaced Persons Camp in South Sudan

Author

Bliss, Jesse, primary, Martin, Stephen, additional, Couturier, Brianne A., additional, Rumunu, John, additional, Azman, Andrew S., additional, Hale, Peter, additional, Sack, David A., additional, Couturier, Marc Roger, additional, Abubakar, Abdinasir, additional, Wamala, Joseph F., additional, Iyer, Anita S., additional, Leung, Daniel T., additional, Bouhenia, Malika, additional, and Luquero, Francisco J., additional

Published
2018
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41. Revisiting the Roles of Culture and Culture-Independent Detection Tests for Campylobacter

Author

Couturier, Marc Roger

Subjects
Adult, Aged, 80 and over, Immunoassay, Male, Bacteriological Techniques, Adolescent, Diagnostic Tests, Routine, Infant, Campylobacter, Middle Aged, Polymerase Chain Reaction, Sensitivity and Specificity, Feces, Young Adult, Predictive Value of Tests, Commentaries, Child, Preschool, Campylobacter Infections, Humans, Female, Prospective Studies, Child, Aged
Abstract

The use of culture-independent diagnostic tests (CIDTs), such as stool antigen tests, as standalone tests for the detection of Campylobacter in stool is increasing. We conducted a prospective, multicenter study to evaluate the performance of stool antigen CIDTs compared to culture and PCR for Campylobacter detection. Between July and October 2010, we tested 2,767 stool specimens from patients with gastrointestinal illness with the following methods: four types of Campylobacter selective media, four commercial stool antigen assays, and a commercial PCR assay. Illnesses from which specimens were positive by one or more culture media or at least one CIDT and PCR were designated "cases." A total of 95 specimens (3.4%) met the case definition. The stool antigen CIDTs ranged from 79.6% to 87.6% in sensitivity, 95.9 to 99.5% in specificity, and 41.3 to 84.3% in positive predictive value. Culture alone detected 80/89 (89.9% sensitivity) Campylobacter jejuni/Campylobacter coli-positive cases. Of the 209 noncases that were positive by at least one CIDT, only one (0.48%) was positive by all four stool antigen tests, and 73% were positive by just one stool antigen test. The questionable relevance of unconfirmed positive stool antigen CIDT results was supported by the finding that noncases were less likely than cases to have gastrointestinal symptoms. Thus, while the tests were convenient to use, the sensitivity, specificity, and positive predictive value of Campylobacter stool antigen tests were highly variable. Given the relatively low incidence of Campylobacter disease and the generally poor diagnostic test characteristics, this study calls into question the use of commercially available stool antigen CIDTs as standalone tests for direct detection of Campylobacter in stool.

Published
2016

47. Textbook Reviewers

Author

Abadie, Jude, Agarwal, Archana M., Bornhorst, Joshua, Casteele, Niels V., Cobbaert, Christa, Couturier, Marc Roger, Delgado, Julio C., Fernandes, Helen, Hamilton, Paul Kevin, Kellogg, Mark, Kumanovics, Attila, Lai, Leslie C.C.L., Lázár-Molnár, Eszter, Murphy, Michael, Nerenz, Robert D., Ntrivalas, Evangelos, Sharif, Adnan, Simundic, Ana-Maria, Smock, Kristi J., Steenkamp, Vanessa, Wang, Ping, and Westblade, Lars

Published
2023
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48. Diagnostic Algorithm for the Diagnosis of Pediatric Parasitic Gastroenteritis

Author

Beal, Stacy G., Couturier, Marc Roger, Gander, Rita M., and Doern, Christopher D.

Subjects
Animals, Humans, Parasites, Original Articles, Intestinal Diseases, Parasitic, Child, Gastroenteritis, Ovum
Abstract

BACKGROUND: Current practices for ordering stool studies in patients with abdominal and gastrointestinal symptoms are not standardized. We hypothesized that an algorithm involving first‐line use of a Cryptosporidium/Giardia combination antigen test and stricter use of ova and parasite (O&P) examinations would be clinically and cost effective. METHODS: In this study, stool O&P test results for pediatric patients in Dallas, Texas, were reviewed. All results obtained between 2009 and 2012 were included. Patient charts were reviewed to determine test results, symptoms, treatment, travel, and past medical history. Using these data, a retrospective modeling study was done to evaluate the utility of a diagnostic algorithm that limits O&P testing to those patients who are immunocompromised or have travelled outside the United States. RESULTS: Over the 3‐year period of this study, we found that the prevalence of gastrointestinal parasitic disease in children was 1.9%. Analysis of the diagnostic algorithm for the judicious use of stool O&P showed that as much as 65% of testing may be unnecessary and could be eliminated. CONCLUSIONS: Our findings show that the prevalence of pediatric gastrointestinal parasitic disease in Texas may be lower than expected. In addition, these data show that a diagnostic algorithm limiting O&P testing may be both clinically and cost effective in low‐prevalence settings. However, such an algorithm would miss a significant number of infections due to Dientamoeba fragilis and Blastocystis hominis.

Published
2014

50. Clinical Microbiology Laboratories' Adoption of Culture-Independent Diagnostic Tests Is a Threat to Foodborne-Disease Surveillance in the United States

Author

Shea, Shari, primary, Kubota, Kristy A., additional, Maguire, Hugh, additional, Gladbach, Stephen, additional, Woron, Amy, additional, Atkinson-Dunn, Robyn, additional, Couturier, Marc Roger, additional, Miller, Melissa B., additional, Shea, Shari, additional, and Gilligan, Peter H., additional

Published
2017
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