47,243 results on '"Cotter A"'
Search Results
2. Kefir4All, a Citizen Science Initiative to Raise Awareness of the Roles that Microbes Play in Food Fermentation
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Liam H. Walsh, Samuel Breselge, José Guilherme Prado Martin, Mairéad Coakley, Eimear Ferguson, Aimee Stapleton, Fiona Crispie, Paul W. O'Toole, and Paul D. Cotter
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Microorganisms are ubiquitous in nature and are central to human, animal, environmental, and planetary health. They play a particularly important role in the food chain and the production of high-quality, safe, and health-promoting foods, especially fermented foods. This important role is not always apparent to members of the public. Here, we describe Kefir4All, a citizen science project designed to provide the general public with an opportunity to expand their awareness, knowledge, and practical skills relating to microbiology, introduced through the medium of producing fermented food, i.e., milk kefir or water kefir. During the course of Kefir4All, 123 citizen scientists, from second-level school and non-school settings, participated in a study to track changes in the microbial composition of kefirs, by performing and recording details of milk kefir or water kefir fermentations they performed in their homes or schools over the21-week project. At the start of the study, the citizen scientists were provided with milk or water kefir grains to initiate the fermentations. Both types of kefir grain are semi-solid, gelatinous-like substances, composed of exopolysaccharides and proteins, containing a symbiotic community of bacteria and yeast. The experimental component of the project was complemented by a number of education and outreach events, including career talks and a site visit to our research center (Kefir Day). At the end of the study, a report was provided to each citizen scientist, in which individualized results of their fermenting activities were detailed. A number of approaches were taken to obtain feedback and other insights from the citizen scientists. Evaluations took place before and after theKefir4All project to gauge the citizen scientist's self-reported awareness, knowledge, and interest in microbiology and fermented foods. Further insights into the level of citizen science participation were gained through assessing the number of samples returned for analysis and the level of participation of the citizen scientists throughout the project. Notably, the survey results revealed a self-reported, increased interest in, and general knowledge of, science among the Kefir4All citizen scientists after undertaking the project and a willingness to take part in further citizen science projects. Ultimately, Kefir4Allrepresents an example of the successful integration of citizen science into existing education and research systems.
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- 2024
3. The GRBSN webtool: An open-source repository for gamma-ray burst-supernova associations
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Finneran, Gabriel, Cotter, Laura, and Martin-Carrillo, Antonio
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
This paper presents the GRBSN webtool, a public facing application which hosts the most complete list of GRB-SN associations to date. In contrast to other repositories of supernova or gamma-ray burst data, this tool brings together all of the information required to study a GRB-SN association. GRBSN allows users to view and interact with plots of the data; search and filter the whole database; and download all multi-wavelength data related to a GRB-SN association, including radio, X-ray, optical/NIR photometric and spectroscopic data. The tool is fully open source and is hosted on a public GitHub repository, meaning users can upload their own data, flag missing data and suggest improvements. As the number of confirmed GRB-SN associations increases, the webtool will provide a robust framework in which to catalogue these associations and their associated data. The web application is freely available and publicly accessible at https://grbsn.watchertelescope.ie., Comment: 16 pages, 7 figures
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- 2024
4. High-Statistics Measurement of the Cosmic-Ray Electron Spectrum with H.E.S.S
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Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaoui, M., Brose, R., Brown, A., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Bylund, T., Casanova, S., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Collins, T., Cotter, G., Mbarubucyeye, J. Damascene, Devin, J., Djuvsland, J., Dmytriiev, A., Egberts, K., Einecke, S., Ernenwein, J. -P., Fegan, S., Feijen, K., Fontaine, G., Funk, S., Gabici, S., Gallant, Y. A., Glicenstein, J. F., Glombitza, J., Grolleron, G., Heß, B., Hofmann, W., Holch, T. L., Holler, M., Horns, D., Huang, Zhiqiu, Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzynski, K., Kerszberg, D., Khatoon, R., Khelifi, B., Kluzniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemiere, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Luashvili, A., Mackey, J., Malyshev, D., Marandon, V., Marinos, P., Marti-Devesa, G., Marx, R., Meyer, M., Mitchell, A., Moderski, R., Moghadam, M. O., Mohrmann, L., Montanari, A., Moulin, E., de Naurois, M., Niemiec, J., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, D., Pensec, U., Peron, G., Pühlhofer, G., Punch, M., Quirrenbach, A., Ravikularaman, S., Regeard, M., Reimer, A., Reimer, O., Reis, I., Ren, H., Reville, B., Rieger, F., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Salzmann, H., Santangelo, A., Sasaki, M., Schäfer, J., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Sharma, A., Sol, H., Spencer, S., Stawarz, L., Steinmassl, S., Steppa, C., Suzuki, H., Takahashi, T., Tanaka, T., Taylor, A. M., Terrier, R., Tsirou, M., van Eldik, C., Vecchi, M., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zdziarski, A. A., Zech, A., and Zywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Owing to their rapid cooling rate and hence loss-limited propagation distance, cosmic-ray electrons and positrons (CRe) at very high energies probe local cosmic-ray accelerators and provide constraints on exotic production mechanisms such as annihilation of dark matter particles. We present a high-statistics measurement of the spectrum of CRe candidate events from 0.3 to 40 TeV with the High Energy Stereoscopic System (H.E.S.S.), covering two orders of magnitude in energy and reaching a proton rejection power of better than $10^{4}$. The measured spectrum is well described by a broken power law, with a break around 1 TeV, where the spectral index increases from $\Gamma_1 = 3.25$ $\pm$ 0.02 (stat) $\pm$ 0.2 (sys) to $\Gamma_2 = 4.49$ $\pm$ 0.04 (stat) $\pm$ 0.2 (sys). Apart from the break, the spectrum is featureless. The absence of distinct signatures at multi-TeV energies imposes constraints on the presence of nearby CRe accelerators and the local CRe propagation mechanisms., Comment: main paper: 8 pages, 4 figures, supplemental material: 12 pages, 14 figures, accepted for publication in Physical Review Letters https://journals.aps.org/prl/
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- 2024
5. Hidden by a star: the redshift and the offset broad line of the Flat Spectrum Radio Quasar PKS 0903-57
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Goldoni, P., Boisson, C., Pita, S., D'Ammando, F., Kasai, E., Max-Moerbeck, W., Backes, M., and Cotter, G.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Context: PKS 0903-57 is a little-studied gamma-ray blazar which has recently attracted considerable interest due to the strong flaring episodes observed since 2020 in HE (100 MeV < E < 100 GeV) and VHE (100 GeV < E < 10 TeV) gamma-rays. Its nature and properties are still not well determined. In particular, it is unclear whether PKS 0903-57 is a BL Lac or a Flat Spectrum Radio Quasar (FSRQ), while its redshift estimation relies on a possibly misassociated low signal-to-noise spectrum. Aim: We aim to reliably measure the redshift of the blazar and to determine its spectral type and luminosity in the optical range. Methods: We performed spectroscopy of the optical counterpart of the blazar using the South African Large Telescope (SALT) and the Very Large Telescope (VLT) and monitored it photometrically with the Rapid Eye Mount (REM) telescope. Results: We firmly measured the redshift of the blazar as z= 0.2621 +/- 0.0006 thanks to the detection of five narrow optical lines. The detection of a symmetric broad Halpha line with Full Width at Half Maximum (FWHM) of 4020 +/- 30 km/s together with a jet-dominated continuum leads us to classify it as a FSRQ. Finally, we detected with high significance a redshift offset (about 1500 km/s) between the broad line and the host. This is the first time that such an offset is unequivocally detected in a VHE blazar, possibly pointing to a very peculiar accretion configuration, a merging system, or a recoiling Black Hole., Comment: Astronomy and Astrophysics Letters, Accepted
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- 2024
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6. asQ: parallel-in-time finite element simulations using ParaDiag for geoscientific models and beyond
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Hope-Collins, Joshua, Hamdan, Abdalaziz, Bauer, Werner, Mitchell, Lawrence, and Cotter, Colin
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Mathematics - Numerical Analysis - Abstract
Modern high performance computers are massively parallel; for many PDE applications spatial parallelism saturates long before the computer's capability is reached. Parallel-in-time methods enable further speedup beyond spatial saturation by solving multiple timesteps simultaneously to expose additional parallelism. ParaDiag is a particular approach to parallel-in-time based on preconditioning the simultaneous timestep system with a perturbation that allows block diagonalisation via a Fourier transform in time. In this article, we introduce asQ, a new library for implementing ParaDiag parallel-in-time methods, with a focus on applications in the geosciences, especially weather and climate. asQ is built on Firedrake, a library for the automated solution of finite element models, and the PETSc library of scalable linear and nonlinear solvers. This enables asQ to build ParaDiag solvers for general finite element models and provide a range of solution strategies, making testing a wide array of problems straightforward. We use a quasi-Newton formulation that encompasses a range of ParaDiag methods, and expose building blocks for constructing more complex methods. The performance and flexibility of asQ is demonstrated on a hierarchy of linear and nonlinear atmospheric flow models. We show that ParaDiag can offer promising speedups and that asQ is a productive testbed for further developing these methods., Comment: 30 pages, 15 figures. To be submitted to journal
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- 2024
7. Searching for GEMS: TOI-6383Ab, a giant planet transiting an M3-dwarf star in a binary system
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Bernabò, Lia Marta, Kanodia, Shubham, Canas, Caleb I., Cochran, William D., Csizmadia, Szilárd, Mahadevan, Suvrath, Stefánsson, Gudhmundur, Gupta, Arvind F., Monson, Andrew, Kobulnicky, Henry A., Larsen, Alexander K., Cotter, Ethan G., Birkholz, Alexina, Swaby, Tera N., Zeimann, Gregory, Bender, Chad F., Diddams, Scott A., Libby-Roberts, Jessica E., Lin, Andrea S. J., Ninan, Joe P., Rauer, Heike, Reji, Varghese, Robertson, Paul, Roy, Arpita, and Schwab, Christian
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We report on the discovery of a transiting giant planet around the 3500 K M3-dwarf star TOI-6383A located 172 pc from Earth. It was detected by the Transiting Exoplanet Survey Satellite (TESS) and confirmed by a combination of ground-based follow-up photometry and precise radial velocity measurements. This planet has an orbital period of $\sim$1.791 days, mass of 1.040$\pm$0.094 $M_J$ and a radius of 1d.008$^{+0.036}_{-0.033} ~R_J$, resulting in a mean bulk density of 1.26$^{+0.18}_{-0.17}$ g cm$^{-3}$. TOI-6383A has an M-dwarf companion star, TOI-6383B, which has a stellar effective temperature $T_{eff}$ $\sim$ 3100 K and a projected orbital separation of 3100 AU. TOI-6383A is a low-mass dwarf star hosting a giant planet and is an intriguing object for planetary evolution studies due to its high planet-to-star mass ratio. This discovery is part of the \textit{Searching for Giant Exoplanets around M-dwarf Stars (GEMS)} Survey, intending to provide robust and accurate estimates of the occurrence of GEMS and the statistics on their physical and orbital parameters. This paper presents an interesting addition to the small number of confirmed GEMS, particularly notable since its formation necessitates massive, ust-rich protoplanetary discs and high accretion efficiency ($>$ 10\%)., Comment: 20 pages, 8 figures
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- 2024
8. Computational forms for binary particle interactions at different levels of anisotropy
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Everett, Christopher N. and Cotter, Garret
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Particle interactions are key elements of many dynamical systems. In the context of systems described by a Boltzmann equation, such interactions may be described by a collision integral, a multidimensional integral over the momentum-phase space of the interaction. This integral is often simplified by assuming isotropic particle distributions; however, such an assumption places constraints on the dynamics of the system. This paper presents computational forms of the collision integral for relativistic, binary interactions at three levels of anisotropy, including a novel form in the isotropic case. All these forms are split into two parts, an absorption and an emission spectrum, which may be pre-calculated via numerical integration for simulation purposes. We demonstrate the use of these forms by comparison with the analytically integrated, isotropic emission spectrum of electron-positron annihilation, which are shown to agree to numerical precision. The emission spectrum is then further extended to axisymmetric particle distributions, where two-dimensional spectral maps can be generated to provide new insight., Comment: 8 pages, 3 figures
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- 2024
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9. Taking Responsibility for Meaning and Mattering: An Agential Realist Approach to Generative AI and Literacy
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Priya C. Kumar, Kelley Cotter, and Laura Y. Cabrera
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Questions and concerns about artificial intelligence (AI) technologies in education reached a fever pitch with the arrival of publicly accessible, user-facing generative AI systems, especially ChatGPT. Many of these issues will require regulation and collective action to address. But when it comes to generative AI and literacy, we argue that posthuman perspectives can help literacy scholars and practitioners reframe some concerns into questions that open new areas of inquiry. Agential realism in particular offers a useful perspective for exploring how generative AI matters in literacy practices, not as a unilaterally destructive force, but as a set of phenomena that intra-actively reconfigures literacy practices. As a sociocultural (and as we argue, sociotechnical) practice, literacy arises out of the entanglement of bodies, spaces, contexts, positions, histories, and technologies. Generative AI is another in a long line of technologies that reconfigures literacy practices. In this article, we briefly explain how generative AI systems work, focusing on text-based systems called Large Language Models (LLMs), and suggest ways that generative AI may reconfigure the sociocultural practice of literacy. We then offer three provocations to shift discussions about generative AI and literacy (1) from concerns about intentionality to questions of responsibility, (2) from concerns about authenticity to questions of mattering, and (3) from concerns about imitation to questions of multifarious communication. We conclude by encouraging literacy scholars and practitioners to draw inspiration from critical literacy efforts to discover what matters when it comes to generative AI and literacy.
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- 2024
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10. Leveraging Technology to Support Teachers' Fidelity of Universal Classroom Management Interventions: Lessons Learned and Future Applications
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Stephanie D. Smith, Fayth Walbridge, Tiffany Harris, Mairin C. Cotter, Rachel Kaplan, Brittany Garza, Zachary Wilde, Arianna Delgadillo, Richard Mohn, and Brad Dufrene
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The Good Behavior Game (GBG), a universal classroom management intervention, has shown clear benefits in promoting the behavioral, social-emotional, and academic development of students. However, the quality with which this intervention is delivered tends to diminish over time, which decreases the likelihood of these positive outcomes. By leveraging the benefits of technology, we built a sophisticated online platform to support teachers' fidelity of the GBG in collaboration with expert consultants and education partners. This paper details initial steps to develop and refine GBG Technology (GBG Tech). Three teacher consultants and two experts in technology-enhanced and classroom management interventions provided ongoing feedback as GBG Tech was initially developed through a rapid prototyping approach by a team of high-tech engineers. Twenty-four teachers participated in focus groups to inform subsequent revisions of the technology, and seven teachers tested the feasibility of GBG Tech in their classrooms for 6 weeks. As anticipated, teachers found GBG Tech to be acceptable, understandable, and feasible to use. Moreover, teachers reached fidelity quickly (M = 2.43 weeks), sustained fidelity for 6 weeks, and delivered the GBG at the recommended dosage. The results of this study informed a full version of GBG Tech that is ready for large-scale testing and a set of design principles intended to guide the development of other technology-delivered interventions aimed at sustaining fidelity in authentic classroom settings.
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- 2024
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11. Distance estimation of gamma-ray emitting BL Lac objects from imaging observations
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Nilsson, K., Ramazani, V. Fallah, Lindfors, E., Goldoni, P., González, J. Becerra, Pulido, J. A. Acosta, Clavero, R., Otero-Santos, J., Pursimo, T., Pita, S., Kouch, P. M., Boisson, C., Backes, M., Cotter, G., D'Ammando, F., and Kasai, E.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
Direct redshift determination of BL Lac objects is highly challenging as the emission in the optical and near-infrared (NIR) bands is largely dominated by the non-thermal emission from the relativistic jet that points very close to our line of sight. Therefore, their optical spectra often show no emission lines from the host galaxy. In this work, we aim to overcome this difficulty by attempting to detect the host galaxy and derive redshift constraints based on assumptions on the galaxy magnitude ("imaging redshifts"). Imaging redshifts are derived by obtaining deep optical images under good seeing conditions, so that it is possible to detect the host galaxy as weak extension of the point-like source. We then derive the imaging redshift by using the host galaxy as a standard candle using two different methods. We determine imaging redshift for 9 out of 17 blazars that we observed as part of this program. The redshift range of these targets is 0.28-0.60 and the two methods used to derive the redshift give very consistent results within the uncertainties. We also performed a detailed comparison of the imaging redshifts with those obtained by other methods, like direct spectroscopic constraints or looking for groups of galaxies close to the blazar. We show that the constraints from different methods are consistent and that for example in the case of J2156.0+1818, which is the most distant source for which we detect the host galaxy, combining the three constraints narrows down the redshift to $0.63
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- 2024
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12. Searching for GEMS: Characterizing Six Giant Planets around Cool Dwarfs
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Kanodia, Shubham, Gupta, Arvind F., Canas, Caleb I., Bernabo, Lia Marta, Reji, Varghese, Han, Te, Brady, Madison, Seifahrt, Andreas, Cochran, William D., Morrell, Nidia, Basant, Ritvik, Bean, Jacob, Bender, Chad F., de Beurs, Zoe L., Bieryla, Allyson, Birkholz, Alexina, Brown, Nina, Chapman, Franklin, Ciardi, David R., Clark, Catherine A., Cotter, Ethan G., Diddams, Scott A., Halverson, Samuel, Hawley, Suzanne, Hebb, Leslie, Holcomb, Rae, Howell, Steve B., Kobulnicky, Henry A., Kowalski, Adam F., Larsen, Alexander, Libby-Roberts, Jessica, Lin, Andrea S. J., Lund, Michael B., Luque, Rafael, Monson, Andrew, Ninan, Joe P., Parker, Brock A., Patel, Nishka, Rodruck, Michael, Ross, Gabrielle, Roy, Arpita, Schwab, Christian, Stefánsson, Guðmundur, Thoms, Aubrie, and Vanderburg, Andrew
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Transiting giant exoplanets around M-dwarf stars (GEMS) are rare, owing to the low-mass host stars. However, the all-sky coverage of TESS has enabled the detection of an increasingly large number of them to enable statistical surveys like the \textit{Searching for GEMS} survey. As part of this endeavour, we describe the observations of six transiting giant planets, which includes precise mass measurements for two GEMS (K2-419Ab, TOI-6034b) and statistical validation for four systems, which includes validation and mass upper limits for three of them (TOI-5218b, TOI-5616b, TOI-5634Ab), while the fourth one -- TOI-5414b is classified as a `likely planet'. Our observations include radial velocities from the Habitable-zone Planet Finder on the Hobby-Eberly Telescope, and MAROON-X on Gemini-North, along with photometry and high-contrast imaging from multiple ground-based facilities. In addition to TESS photometry, K2-419Ab was also observed and statistically validated as part of the K2 mission in Campaigns 5 and 18, which provides precise orbital and planetary constraints despite the faint host star and long orbital period of $\sim 20.4$ days. With an equilibrium temperature of only 380 K, K2-419Ab is one of the coolest known well-characterized transiting planets. TOI-6034 has a late F-type companion about 40\arcsec~away, making it the first GEMS host star to have an earlier main-sequence binary companion. These confirmations add to the existing small sample of confirmed transiting GEMS., Comment: Accepted in AJ
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- 2024
13. Very-high-energy $\gamma$-ray emission from young massive star clusters in the Large Magellanic Cloud
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Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Brose, R., Brown, A., Brun, F., Bruno, B., Burger-Scheidlin, C., Casanova, S., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Cristofari, P., Devin, J., Djannati-Ataï, A., Djuvsland, J., Dmytriiev, A., Egberts, K., Einecke, S., Feijen, K., Filipovic, M., Fontaine, G., Funk, S., Gabici, S., Gallant, Y. A., Glicenstein, J. F., Glombitza, J., Grolleron, G., Haerer, L., Heß, B., Hinton, J. A., Hofmann, W., Holch, T. L., Horns, D., Huang, Zhiqiu, Jamrozy, M., Jankowsky, F., Jung-Richardt, I., Kasai, E., Katarzyński, K., Khatoon, R., Khélifi, B., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Mackey, J., Marandon, V., Martí-Devesa, G., Marx, R., Mehta, A., Mitchell, A., Moderski, R., Moghadam, M. O., Mohrmann, L., Montanari, A., Moulin, E., de Naurois, M., Niemiec, J., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Pensec, U., Peron, G., Pühlhofer, G., Quirrenbach, A., Ravikularaman, S., Regeard, M., Reimer, A., Reimer, O., Ren, H., Renaud, M., Reville, B., Rieger, F., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sabri, K., Sahakian, V., Salzmann, H., Santangelo, A., Sasaki, M., Schäfer, J., Schüssler, F., Schutte, H. M., Sol, H., Spencer, S., Stawarz, Ł., Steinmassl, S., Steppa, C., Streil, K., Sushch, I., Taylor, A. M., Terrier, R., Tsirou, M., Tsuji, N., van Eldik, C., Vecchi, M., Venter, C., Vink, J., Wagner, S. J., White, R., Wierzcholska, A., Zacharias, M., Zdziarski, A. A., Zech, A., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Tarantula Nebula in the Large Magellanic Cloud is known for its high star formation activity. At its center lies the young massive star cluster R136, providing a significant amount of the energy that makes the nebula shine so brightly at many wavelengths. Recently, young massive star clusters have been suggested to also efficiently produce high-energy cosmic rays, potentially beyond PeV energies. Here, we report the detection of very-high-energy $\gamma$-ray emission from the direction of R136 with the High Energy Stereoscopic System, achieved through a multicomponent, likelihood-based modeling of the data. This supports the hypothesis that R136 is indeed a very powerful cosmic-ray accelerator. Moreover, from the same analysis, we provide an updated measurement of the $\gamma$-ray emission from 30 Dor C, the only superbubble detected at TeV energies presently. The $\gamma$-ray luminosity above $0.5\,\mathrm{TeV}$ of both sources is $(2-3)\times 10^{35}\,\mathrm{erg}\,\mathrm{s}^{-1}$. This exceeds by more than a factor of 2 the luminosity of HESS J1646$-$458, which is associated with the most massive young star cluster in the Milky Way, Westerlund 1. Furthermore, the $\gamma$-ray emission from each source is extended with a significance of $>3\sigma$ and a Gaussian width of about $30\,\mathrm{pc}$. For 30 Dor C, a connection between the $\gamma$-ray emission and the nonthermal X-ray emission appears likely. Different interpretations of the $\gamma$-ray signal from R136 are discussed., Comment: 10+11 pages, 4+6 figures. Corresponding authors: L. Mohrmann, N. Komin
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- 2024
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14. WayveScenes101: A Dataset and Benchmark for Novel View Synthesis in Autonomous Driving
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Zürn, Jannik, Gladkov, Paul, Dudas, Sofía, Cotter, Fergal, Toteva, Sofi, Shotton, Jamie, Simaiaki, Vasiliki, and Mohan, Nikhil
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Graphics ,Computer Science - Robotics - Abstract
We present WayveScenes101, a dataset designed to help the community advance the state of the art in novel view synthesis that focuses on challenging driving scenes containing many dynamic and deformable elements with changing geometry and texture. The dataset comprises 101 driving scenes across a wide range of environmental conditions and driving scenarios. The dataset is designed for benchmarking reconstructions on in-the-wild driving scenes, with many inherent challenges for scene reconstruction methods including image glare, rapid exposure changes, and highly dynamic scenes with significant occlusion. Along with the raw images, we include COLMAP-derived camera poses in standard data formats. We propose an evaluation protocol for evaluating models on held-out camera views that are off-axis from the training views, specifically testing the generalisation capabilities of methods. Finally, we provide detailed metadata for all scenes, including weather, time of day, and traffic conditions, to allow for a detailed model performance breakdown across scene characteristics. Dataset and code are available at https://github.com/wayveai/wayve_scenes., Comment: 7 pages
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- 2024
15. H.E.S.S. observations of the 2021 periastron passage of PSR B1259-63/LS 2883
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Collaboration, H. E. S. S., Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaoui, M., Brose, R., Brown, A., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Caroff, S., Casanova, S., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Mbarubucyeye, J. Damascene, Devin, J., Djuvsland, J., Dmytriiev, A., Egberts, K., Einecke, S., Ernenwein, J. -P., Fontaine, G., Funk, S., Gabici, S., Gallant, Y. A., Glawion, D., Glicenstein, J. F., Goswami, P., Grolleron, G., Haerer, L., Heß, B., Hofmann, W., Holch, T. L., Holler, M., Huang, Zhiqiu, Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Khangulyan, D., Khatoon, R., Khélifi, B., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Mackey, J., Malyshev, D., Martí-Devesa, G., Marx, R., Mehta, A., Meintjes, P. J., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Pensec, U., Peron, G., Prokhorov, D. A., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reimer, A., Reimer, O., Reis, I., Ren, H., Rieger, F., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Salzmann, H., Santangelo, A., Sasaki, M., Schäfer, J., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Spencer, S., Stawarz, Ł., Steenkamp, R., Steinmassl, S., Steppa, C., Streil, K., Sushch, I., Takahashi, T., Tanaka, T., Taylor, A. M., Terrier, R., Thorpe-Morgan, C., Tluczykont, M., Unbehaun, T., van Eldik, C., van Soelen, B., Vecchi, M., Venter, C., Vink, J., Wach, T., Wagner, S. J., Werner, F., Wierzcholska, A., Zacharias, M., Zdziarski, A. A., Zech, A., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
PSR B1259-63 is a gamma-ray binary system that hosts a pulsar in an eccentric orbit, with a 3.4 year period, around an O9.5Ve star. At orbital phases close to periastron passages, the system radiates bright and variable non-thermal emission. We report on an extensive VHE observation campaign conducted with the High Energy Stereoscopic System, comprised of ~100 hours of data taken from $t_p-24$ days to $t_p+127$ days around the system's 2021 periastron passage. We also present the timing and spectral analyses of the source. The VHE light curve in 2021 is consistent with the stacked light curve of all previous observations. Within the light curve, we report a VHE maximum at times coincident with the third X-ray peak first detected in the 2021 X-ray light curve. In the light curve -- although sparsely sampled in this time period -- we see no VHE enhancement during the second disc crossing. In addition, we see no correspondence to the 2021 GeV flare in the VHE light curve. The VHE spectrum obtained from the analysis of the 2021 dataset is best described by a power law of spectral index $\Gamma = 2.65 \pm 0.04_{\text{stat}}$ $\pm 0.04_{\text{sys}}$, a value consistent with the previous H.E.S.S. observations of the source. We report spectral variability with a difference of $\Delta \Gamma = 0.56 ~\pm~ 0.18_{\text{stat}}$ $~\pm~0.10_{\text{sys}}$ at 95% c.l., between sub-periods of the 2021 dataset. We also find a linear correlation between contemporaneous flux values of X-ray and TeV datasets, detected mainly after $t_p+25$ days, suggesting a change in the available energy for non-thermal radiation processes. We detect no significant correlation between GeV and TeV flux points, within the uncertainties of the measurements, from $\sim t_p-23$ days to $\sim t_p+126$ days. This suggests that the GeV and TeV emission originate from different electron populations., Comment: accepted to A&A
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- 2024
16. Unveiling extended gamma-ray emission around HESS J1813-178
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Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Baktash, A., Martins, V. Barbosa, Barnard, J., Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaoui, M., Breuhaus, M., Brose, R., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Caroff, S., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chambery, P., Chand, T., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Mbarubucyeye, J. Damascene, Djannati-Ataï, A., Dmytriiev, A., Doroshenko, V., Einecke, S., Ernenwein, J. -P., Feijen, K., Filipovic, M., Fontaine, G., Füßling, M., Funk, S., Gabici, S., Gallant, Y. A., Ghafourizadeh, S., Giavitt, G., Glawion, D., Glicenstein, J. F., Goswami, P., Grolleron, G., Grondin, M. -H., Hinton, J. A., Hofmann, W., Holch, T. L., Holler, M., Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Katarzyński, K., Khatoon, R., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Mackey, J., Malyshev, D., Marandon, V., Marinos, P., Martí-Devesa, G., Marx, R., Mehta, A., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., Noel, A. Priyana, O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Prokhorov, D. A., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reichherzer, P., Reimer, A., Reimer, O., Ren, H., Renaud, M., Reville, B., Rieger, F., Roellinghoff, G., Rudak, B., Sahakian, V., Salzmann, H., Sasaki, M., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Specovius, A., Spencer, S., Steenkamp, R., Steinmassl, S., Steppa, C., Sushch, I., Suzuki, H., Takahashi, T., Tanaka, T., Terrier, R., Tluczykont, M., Tsuji, N., Unbehaun, T., van Eldik, C., Vecchi, M., Veh, J., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zargaryan, D., Zdziarski, A. A., Zouari, S., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
HESS J1813$-$178 is a very-high-energy $\gamma$-ray source spatially coincident with the young and energetic pulsar PSR J1813$-$1749 and thought to be associated with its pulsar wind nebula (PWN). Recently, evidence for extended high-energy emission in the vicinity of the pulsar has been revealed in the Fermi Large Area Telescope (LAT) data. This motivates revisiting the HESS J1813$-$178 region, taking advantage of improved analysis methods and an extended data set. Using data taken by the High Energy Stereoscopic System (H.E.S.S.) experiment and the Fermi-LAT, we aim to describe the $\gamma$-ray emission in the region with a consistent model, to provide insights into its origin. We performed a likelihood-based analysis on 32 hours of H.E.S.S. data and 12 years of Fermi-LAT data and fit a spectro-morphological model to the combined datasets. These results allowed us to develop a physical model for the origin of the observed $\gamma$-ray emission in the region. In addition to the compact very-high-energy $\gamma$-ray emission centered on the pulsar, we find a significant yet previously undetected component along the Galactic plane. With Fermi-LAT data, we confirm extended high-energy emission consistent with the position and elongation of the extended emission observed with H.E.S.S. These results establish a consistent description of the emission in the region from GeV energies to several tens of TeV. This study suggests that HESS J1813$-$178 is associated with a $\gamma$-ray PWN powered by PSR J1813$-$1749. A possible origin of the extended emission component is inverse Compton emission from electrons and positrons that have escaped the confines of the pulsar and form a halo around the PWN., Comment: 13+5 pages, 13+11 figures. Accepted for publication in A&A. Corresponding authors: T.Wach, A.Mitchell, V.Joshi, P.Chamb\'ery
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- 2024
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17. Spectrum and extension of the inverse-Compton emission of the Crab Nebula from a combined Fermi-LAT and H.E.S.S. analysis
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Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Baktash, A., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bradascio, F., Breuhaus, M., Brose, R., Brown, A., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Bylund, T., Caroff, S., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chambery, P., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Cristofari, P., Devin, J., Djannati-Ataï, A., Djuvsland, J., Dmytriiev, A., Einecke, S., Ernenwein, J. -P., Fegan, S., Feijen, K., Filipović, M., Fontaine, G., Füßling, M., Funk, S., Gabici, S., Gallant, Y. A., Giavitto, G., Glawion, D., Glicenstein, J. F., Glombitza, J., Goswami, P., Grolleron, G., Grondin, M. -H., Haerer, L., Hinton, J. A., Hofmann, W., Holch, T. L., Holler, M., Horns, D., Jamrozy, M., Jankowsky, F., Joshi, V., Kasai, E., Katarzyński, K., Khatoon, R., Khélifi, B., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Luashvili, A., Mackey, J., Malyshev, D., Marandon, V., Marinos, P., Martí-Devesa, G., Marx, R., Mehta, A., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Prokhorov, D. A., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reichherzer, P., Reimer, A., Reimer, O., Ren, H., Renaud, M., Reville, B., Rieger, F., Roellinghoff, G., Rudak, B., Sahakian, V., Salzmann, H., Sasaki, M., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Specovius, A., Spencer, S., Stawarz, Ł., Steenkamp, R., Steinmassl, S., Steppa, C., Streil, K., Sushch, I., Suzuki, H., Takahashi, T., Tanaka, T., Terrier, R., Tluczykont, M., Tsuji, N., Unbehaun, T., van Eldik, C., Vecchi, M., Veh, J., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zargaryan, D., Zdziarski, A. A., Zech, A., Zouari, S., Żywucka, N., and Harding, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Crab Nebula is a unique laboratory for studying the acceleration of electrons and positrons through their non-thermal radiation. Observations of very-high-energy $\gamma$ rays from the Crab Nebula have provided important constraints for modelling its broadband emission. We present the first fully self-consistent analysis of the Crab Nebula's $\gamma$-ray emission between 1 GeV and $\sim$100 TeV, that is, over five orders of magnitude in energy. Using the open-source software package Gammapy, we combined 11.4 yr of data from the Fermi Large Area Telescope and 80 h of High Energy Stereoscopic System (H.E.S.S.) data at the event level and provide a measurement of the spatial extension of the nebula and its energy spectrum. We find evidence for a shrinking of the nebula with increasing $\gamma$-ray energy. Furthermore, we fitted several phenomenological models to the measured data, finding that none of them can fully describe the spatial extension and the spectral energy distribution at the same time. Especially the extension measured at TeV energies appears too large when compared to the X-ray emission. Our measurements probe the structure of the magnetic field between the pulsar wind termination shock and the dust torus, and we conclude that the magnetic field strength decreases with increasing distance from the pulsar. We complement our study with a careful assessment of systematic uncertainties., Comment: 18+6 pages, 15+2 figures. Accepted for publication in A&A. Corresponding authors: M. Meyer, L. Mohrmann, T. Unbehaun. v2: after A&A language editing
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- 2024
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18. Dark Matter Line Searches with the Cherenkov Telescope Array
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Abe, S., Abhir, J., Abhishek, A., Acero, F., Acharyya, A., Adam, R., Aguasca-Cabot, A., Agudo, I., Aguirre-Santaella, A., Alfaro, J., Alfaro, R., Alvarez-Crespo, N., Batista, R. Alves, Amans, J. -P., Amato, E., Ambrosi, G., Angel, L., Aramo, C., Arcaro, C., Arnesen, T. T. H., Arrabito, L., Asano, K., Ascasibar, Y., Aschersleben, J., Ashkar, H., Backes, M., Baktash, A., Balazs, C., Balbo, M., Larriva, A. Baquero, Martins, V. Barbosa, de Almeida, U. Barres, Barrio, J. A., Batković, I., Batzofin, R., Baxter, J., González, J. Becerra, Beck, G., Benbow, W., Berge, D., Bernardini, E., Bernete, J., Bernlöhr, K., Berti, A., Bertucci, B., Bhattacharjee, P., Bhattacharyya, S., Bigongiari, C., Biland, A., Bissaldi, E., Biteau, J., Blanch, O., Blazek, J., Bocchino, F., Boisson, C., Bolmont, J., Bonnoli, G., Bonollo, A., Bordas, P., Bosnjak, Z., Bottacini, E., Böttcher, M., Bringmann, T., Bronzini, E., Brose, R., Brown, A. M., Brunelli, G., Bulgarelli, A., Bulik, T., Burelli, I., Burmistrov, L., Burton, M., Buscemi, M., Bylund, T., Cailleux, J., Campoy-Ordaz, A., Cantlay, B. K., Capasso, G., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Caroff, S., Carosi, A., Carosi, R., Carquin, E., Carrasco, M. -S., Cassol, F., Castaldini, L., Castrejon, N., Castro-Tirado, A. J., Cerasole, D., Cerruti, M., Chadwick, P. M., Chaty, S., Chen, A. W., Chernyakova, M., Chiavassa, A., Chudoba, J., Chytka, L., Cicciari, G. M., Cifuentes, A., Araujo, C. H. Coimbra, Colapietro, M., Conforti, V., Conte, F., Contreras, J. L., Costa, A., Costantini, H., Cotter, G., Cristofari, P., Cuevas, O., Curtis-Ginsberg, Z., D'Amico, G., D'Ammando, F., Dai, S., Dalchenko, M., Dazzi, F., De Angelis, A., de Lavergne, M. de Bony, De Caprio, V., Pino, E. M. de Gouveia Dal, De Lotto, B., De Lucia, M., de Menezes, R., de Naurois, M., de Souza, V., del Peral, L., del Valle, M. V., Giler, A. G. Delgado, Mengual, J. Delgado, Delgado, C., Dell'aiera, M., della Volpe, D., Depaoli, D., Di Girolamo, T., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Diebold, S., Dinesh, A., Djuvsland, J., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Dörner, J., Doro, M., Dournaux, J. -L., Duangchan, C., Dubos, C., Ducci, L., Dwarkadas, V. V., Ebr, J., Eckner, C., Egberts, K., Einecke, S., Elsässer, D., Emery, G., Errando, M., Escanuela, C., Escarate, P., Godoy, M. Escobar, Escudero, J., Esposito, P., Ettori, S., Falceta-Goncalves, D., Fedorova, E., Fegan, S., Feng, Q., Ferrand, G., Ferrarotto, F., Fiandrini, E., Fiasson, A., Filipovic, M., Fioretti, V., Fiori, M., Foffano, L., Guiteras, L. Font, Fontaine, G., Fröse, S., Fukazawa, Y., Fukui, Y., Furniss, A., Galanti, G., Galaz, G., Galelli, C., Gallozzi, S., Gammaldi, V., Garczarczyk, M., Gasbarra, C., Gasparrini, D., Ghalumyan, A., Gianotti, F., Giarrusso, M., Paiva, J. G. Giesbrecht Formiga, Giglietto, N., Giordano, F., Giuffrida, R., Glicenstein, J. -F., Glombitza, J., Goldoni, P., González, J. M., González, M. M., Coelho, J. Goulart, Gradetzke, T., Granot, J., Grasso, D., Grau, R., Gréaux, L., Green, D., Green, J. G., Grolleron, G., Guedes, L. M. V., Gueta, O., Hackfeld, J., Hadasch, D., Hamal, P., Hanlon, W., Hara, S., Harvey, V. M., Hassan, T., Hayashi, K., Heß, B., Heckmann, L., Heller, M., Cadena, S. Hernández, Hervet, O., Hinton, J., Hiroshima, N., Hnatyk, B., Hnatyk, R., Hofmann, W., Holder, J., Horan, D., Horvath, P., Hovatta, T., Hrabovsky, M., Hrupec, D., Iarlori, M., Inada, T., Incardona, F., Inoue, S., Inoue, Y., Iocco, F., Iori, M., Ishio, K., Jamrozy, M., Janecek, P., Jankowsky, F., Jean, P., Quiles, J. Jimenez, Jin, W., Juramy-Gilles, C., Jurysek, J., Kagaya, M., Kalekin, O., Karas, V., Katagiri, H., Kataoka, J., Kaufmann, S., Kazanas, D., Kerszberg, D., Kieda, D. B., Kleiner, T., Kluge, G., Kobayashi, Y., Kohri, K., Komin, N., Kornecki, P., Kosack, K., Kowal, G., Kubo, H., Kushida, J., La Barbera, A., La Palombara, N., Láinez, M., Lamastra, A., Lapington, J., Laporte, P., Lazarević, S., Lazendic-Galloway, J., Lemoine-Goumard, M., Lenain, J. -P., Leone, F., Leonora, E., Leto, G., Lindfors, E., Linhoff, M., Liodakis, I., Lipniacka, A., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Bahilo, J. Lozano, Luque-Escamilla, P. L., Macias, O., Majumdar, P., Mallamaci, M., Malyshev, D., Mandat, D., Manicò, G., Mariotti, M., Márquez, I., Marquez, P., Marsella, G., Martí, J., Martínez, G. A., Martínez, M., Martinez, O., Marty, C., Mas-Aguilar, A., Mastropietro, M., Mazin, D., Menchiari, S., Mestre, E., Meunier, J. -L., Meyer, D. M. -A., Meyer, M., Miceli, D., Miceli, M., Michailidis, M., Michałowski, J., Miener, T., Miranda, J. M., Mitchell, A., Mizote, M., Mizuno, T., Moderski, R., Molero, M., Molfese, C., Molina, E., Montaruli, T., Moralejo, A., Morcuende, D., Morselli, A., Moulin, E., Zamanillo, V. Moya, Munari, K., Murach, T., Muraczewski, A., Muraishi, H., Nakamori, T., Nayak, A., Nemmen, R., Neto, J. P., Nickel, L., Niemiec, J., Nieto, D., Rosillo, M. Nievas, Nikołajuk, M., Nikolić, L., Nishijima, K., Noda, K., Nosek, D., Novotny, V., Nozaki, S., Ohishi, M., Ohtani, Y., Okumura, A., Olive, J. -F., Ong, R. A., Orienti, M., Orito, R., Orlandini, M., Orlando, E., Orlando, S., Ostrowski, M., Otero-Santos, J., Oya, I., Pagano, I., Pagliaro, A., Palatiello, M., Panebianco, G., Paneque, D., Pantaleo, F. R., Paredes, J. M., Parmiggiani, N., Patricelli, B., Pe'er, A., Pech, M., Pecimotika, M., Pensec, U., Peresano, M., Pérez-Romero, J., Persic, M., Peters, K. P., Petruk, O., Piano, G., Pierre, E., Pietropaolo, E., Pihet, M., Pinchbeck, L., Pirola, G., Pittori, C., Plard, C., Podobnik, F., Pohl, M., Pollet, V., Ponti, G., Prandini, E., Principe, G., Priyadarshi, C., Produit, N., Prouza, M., Pueschel, E., Pühlhofer, G., Pumo, M. L., Queiroz, F., Quirrenbach, A., Rainò, S., Rando, R., Razzaque, S., Regeard, M., Reimer, A., Reimer, O., Reisenegger, A., Rhode, W., Ribeiro, D., Ribó, M., Ricci, C., Richtler, T., Rico, J., Rieger, F., Riitano, L., Rizi, V., Roache, E., Fernandez, G. Rodriguez, Frías, M. D. Rodríguez, Rodríguez-Vázquez, J. J., Romano, P., Romeo, G., Rosado, J., de Leon, A. Rosales, Rowell, G., Rudak, B., Ruiter, A. J., Rulten, C. B., Sadeh, I., Saha, L., Saito, T., Salzmann, H., Sánchez-Conde, M., Sandaker, H., Sangiorgi, P., Sano, H., Santander, M., Santos-Lima, R., Sapienza, V., Šarić, T., Sarkar, A., Sarkar, S., Saturni, F. G., Savarese, S., Scherer, A., Schiavone, F., Schipani, P., Schleicher, B., Schovanek, P., Schubert, J. L., Schwanke, U., Arroyo, M. Seglar, Seitenzahl, I. R., Sergijenko, O., Servillat, M., Siegert, T., Siejkowski, H., Siqueira, C., Sliusar, V., Slowikowska, A., Sol, H., Spencer, S. T., Spiga, D., Stamerra, A., Stanič, S., Starecki, T., Starling, R., Stawarz, Ł., Steppa, C., Hatlen, E. Sæther, Stolarczyk, T., Strišković, J., Suda, Y., Świerk, P., Tajima, H., Tak, D., Takahashi, M., Takeishi, R., Tavernier, T., Tejedor, L. A., Terauchi, K., Teshima, M., Testa, V., Tian, W. W., Tibaldo, L., Tibolla, O., Peixoto, C. J. Todero, Torradeflot, F., Torres, D. F., Tosti, G., Tothill, N., Toussenel, F., Tramacere, A., Travnicek, P., Tripodo, G., Trois, A., Truzzi, S., Tutone, A., Vaclavek, L., Vacula, M., Vallania, P., Vallés, R., van Eldik, C., van Scherpenberg, J., Vandenbroucke, J., Vassiliev, V., Acosta, M. Vázquez, Vecchi, M., Ventura, S., Vercellone, S., Verna, G., Viana, A., Viaux, N., Vigliano, A., Vignatti, J., Vigorito, C. F., Villanueva, J., Visentin, E., Vitale, V., Vodeb, V., Voisin, V., Voitsekhovskyi, V., Vorobiov, S., Voutsinas, G., Vovk, I., Vuillaume, T., Wagner, S. J., Walter, R., White, M., White, R., Wierzcholska, A., Will, M., Williams, D. A., Wohlleben, F., Wolter, A., Yamamoto, T., Yang, L., Yoshida, T., Yoshikoshi, T., Zaharijas, G., Zampieri, L., Sanchez, R. Zanmar, Zavrtanik, D., Zavrtanik, M., Zdziarski, A. A., Zech, A., Zhang, W., Zhdanov, V. I., Ziętara, K., Živec, M., and Zuriaga-Puig, J.
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High Energy Physics - Phenomenology ,Astrophysics - High Energy Astrophysical Phenomena ,High Energy Physics - Experiment - Abstract
Monochromatic gamma-ray signals constitute a potential smoking gun signature for annihilating or decaying dark matter particles that could relatively easily be distinguished from astrophysical or instrumental backgrounds. We provide an updated assessment of the sensitivity of the Cherenkov Telescope Array (CTA) to such signals, based on observations of the Galactic centre region as well as of selected dwarf spheroidal galaxies. We find that current limits and detection prospects for dark matter masses above 300 GeV will be significantly improved, by up to an order of magnitude in the multi-TeV range. This demonstrates that CTA will set a new standard for gamma-ray astronomy also in this respect, as the world's largest and most sensitive high-energy gamma-ray observatory, in particular due to its exquisite energy resolution at TeV energies and the adopted observational strategy focussing on regions with large dark matter densities. Throughout our analysis, we use up-to-date instrument response functions, and we thoroughly model the effect of instrumental systematic uncertainties in our statistical treatment. We further present results for other potential signatures with sharp spectral features, e.g.~box-shaped spectra, that would likewise very clearly point to a particle dark matter origin., Comment: 44 pages JCAP style (excluding author list and references), 19 figures; minor changes to match published version
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- 2024
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19. Diagnostic Yield of Endoscopic Ultrasound in Common Bile Duct Dilation: A Real Breakthrough
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Ferreira, A. I., Xavier, S., Dias de Castro, F., Magalhães, J., Leite, S., and Cotter, J.
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- 2024
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20. Insights on prevalence and incidence of anemia and rapid up-titration of oral heart failure treatment from the STRONG-HF study
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Čelutkienė, Jelena, Čerlinskaitė-Bajorė, Kamilė, Cotter, Gad, Edwards, Christopher, Adamo, Marianna, Arrigo, Mattia, Barros, Marianela, Biegus, Jan, Chioncel, Ovidiu, Cohen-Solal, Alain, Damasceno, Albertino, Diaz, Rafael, Filippatos, Gerasimos, Gayat, Etienne, Kimmoun, Antoine, Léopold, Valentine, Deniau, Benjamin, Metra, Marco, Novosadova, Maria, Pagnesi, Matteo, Pang, Peter S., Ponikowski, Piotr, Saidu, Hadiza, Sliwa, Karen, Takagi, Koji, Ter Maaten, Jozine M., Tomasoni, Daniela, Lam, Carolyn S. P., Voors, Adriaan A., Mebazaa, Alexandre, and Davison, Beth
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- 2024
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21. Examining the healthy human microbiome concept
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Joos, Raphaela, Boucher, Katy, Lavelle, Aonghus, Arumugam, Manimozhiyan, Blaser, Martin J., Claesson, Marcus J., Clarke, Gerard, Cotter, Paul D., De Sordi, Luisa, Dominguez-Bello, Maria G., Dutilh, Bas E., Ehrlich, Stanislav D., Ghosh, Tarini Shankar, Hill, Colin, Junot, Christophe, Lahti, Leo, Lawley, Trevor D., Licht, Tine R., Maguin, Emmanuelle, Makhalanyane, Thulani P., Marchesi, Julian R., Matthijnssens, Jelle, Raes, Jeroen, Ravel, Jacques, Salonen, Anne, Scanlan, Pauline D., Shkoporov, Andrey, Stanton, Catherine, Thiele, Ines, Tolstoy, Igor, Walter, Jens, Yang, Bo, Yutin, Natalia, Zhernakova, Alexandra, Zwart, Hub, Doré, Joël, and Ross, R. Paul
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- 2024
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22. Intraoperative imaging and management of common duct stones during subtotal cholecystectomy
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Johnston, Tawni M., Cotter, Robin R., Soybel, David I., and Santos, B. Fernando
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- 2024
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23. Exercise and endometriosis—is there a promising future? A narrative review
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McKnight, Kathryn, Omotosho, Oluwadamilola, Jassim, Samher, and Cotter, Amanda
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- 2024
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24. The relationship between working memory capacity, bilingualism, and ambiguous relative clause attachment
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Cotter, Beverly T. and Ferreira, Fernanda
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- 2024
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25. The ecological and socioeconomic sustainability of organic agroforestry: a systematic review
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Aaron, Willmott, Amritbir, Riar, Stephane, Saj, Laura, Armengot, Harun, Cicek, Milka, Kiboi, Akanksha, Singh, Ingo, Grass, and Marc, Cotter
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- 2024
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26. Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement
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Lee, Brian P., Witkiewitz, Katie, Mellinger, Jessica, Anania, Frank A., Bataller, Ramon, Cotter, Thomas G., Curtis, Brenda, Dasarathy, Srinivasan, DeMartini, Kelly S., Diamond, Ivan, Diazgranados, Nancy, DiMartini, Andrea F., Falk, Daniel E., Fernandez, Anne C., German, Margarita N., Kamath, Patrick S., Kidwell, Kelley M., Leggio, Lorenzo, Litten, Raye, Louvet, Alexandre, Lucey, Michael R., McCaul, Mary E., Sanyal, Arun J., Singal, Ashwani K., Sussman, Norman L., Terrault, Norah A., Thursz, Mark R., Verna, Elizabeth C., Radaeva, Svetlana, Nagy, Laura E., and Mitchell, Mack C.
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- 2024
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27. High-intensity care for GDMT titration
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Biegus, Jan, Pagnesi, Matteo, Davison, Beth, Ponikowski, Piotr, Mebazaa, Alexander, and Cotter, Gadi
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- 2024
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28. Leveraging Technology to Support Teachers’ Fidelity of Universal Classroom Management Interventions: Lessons Learned and Future Applications
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Smith, Stephanie D., Walbridge, Fayth, Harris, Tiffany, Cotter, Mairin C., Kaplan, Rachel, Garza, Brittany, Wilde, Zachary, Delgadillo, Arianna, Mohn, Richard, and Dufrene, Brad
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- 2024
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29. A mixed finite-element, finite-volume, semi-implicit discretisation for atmospheric dynamics: Spherical geometry
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Melvin, Thomas, Shipway, Ben, Wood, Nigel, Benacchio, Tommaso, Bendall, Thomas, Boutle, Ian, Brown, Alex, Johnson, Christine, Kent, James, Pring, Stephen, Smith, Chris, Zerroukat, Mohamed, Cotter, Colin, and Thuburn, John
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Mathematics - Numerical Analysis ,Mathematical Physics ,65M22 - Abstract
The reformulation of the Met Office's dynamical core for weather and climate prediction previously described by the authors is extended to spherical domains using a cubed-sphere mesh. This paper updates the semi-implicit mixed finite-element formulation to be suitable for spherical domains. In particular the finite-volume transport scheme is extended to take account of non-uniform, non-orthogonal meshes and uses an advective-then-flux formulation so that increment from the transport scheme is linear in the divergence. The resulting model is then applied to a standard set of dry dynamical core tests and compared to the existing semi-implicit semi-Lagrangian dynamical core currently used in the Met Office's operational model., Comment: 26 Pages, 8 Figures, 1 Table
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- 2024
30. Curvature in the very-high energy gamma-ray spectrum of M87
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Collaboration, H. E. S. S., Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Bradascio, F., Brose, R., Brun, F., Bruno, B., Burger-Scheidlin, T. Bulik C., Bylund, T., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Collins, T., Cotter, G., Mbarubucyeye, J. Damascene, Djannati-Ataï, A., Djuvsland, J., Dmytriiev, A., Egberts, K., Einecke, S., Fegan, S., Fontaine, G., Funk, S., Gabici, S., Glicenstein, J. F., Glombitza, J., Grolleron, G., Haerer, L., Hofmann, W., Holch, T. L., Holler, M., Horns, D., Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Khatoon, R., Khélifi, B., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Lypova, I., Luashvili, A., Mackey, J., Malyshev, D., Martí-Devesa, G., Marx, R., Mehta, A., Meyer, M., Mitchell, A., Moderski, R., Moghadam, M. O., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Panny, S., Panter, M., Parsons, R. D., Pensec, U., Pita, S., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reimer, A., Reimer, O., Ren, H., Reville, B., Rieger, F., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Salzmann, H., Santangelo, A., Sasaki, M., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Sol, H., Spencer, S., Stawarz, Ł., Steenkamp, R., Steinmassl, S., Steppa, C., Streil, K., Takahashi, T., Tanaka, T., Taylor, A. M., Terrier, R., Tsirou, M., van Eldik, C., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zdziarski, A. A., Zech, A., Zilberman, P., and Zywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The radio galaxy M87 is a variable very-high energy (VHE) gamma-ray source, exhibiting three major flares reported in 2005, 2008, and 2010. Despite extensive studies, the origin of the VHE gamma-ray emission is yet to be understood. In this study, we investigate the VHE gamma-ray spectrum of M87 during states of high gamma-ray activity, utilizing 20.2$\,$ hours the H.E.S.S. observations. Our findings indicate a preference for a curved spectrum, characterized by a log-parabola model with extra-galactic background light (EBL) model above 0.3$\,$TeV at the 4$\sigma$ level, compared to a power-law spectrum with EBL. We investigate the degeneracy between the absorption feature and the EBL normalization and derive upper limits on EBL models mainly sensitive in the wavelength range 12.4$\,$$\mu$m - 40$\,$$\mu$m., Comment: 10 pages, 7 figures. Accepted for publication in A&A. Corresponding authors: Victor Barbosa Martins, Rahul Cecil, Iryna Lypova, Manuel Meyer, Perri Zilberman. Supplementary material: https://zenodo.org/records/10781524
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- 2024
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31. New limiter regions for multidimensional flows
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Woodfield, James, Weller, Hilary, and Cotter, Colin J
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Mathematics - Numerical Analysis ,Physics - Fluid Dynamics - Abstract
Accurate transport algorithms are crucial for computational fluid dynamics and more accurate and efficient schemes are always in development. One dimensional limiting is commonly employed to suppress nonphysical oscillations. However, the application of such limiters can reduce accuracy. It is important to identify the weakest set of sufficient conditions required on the limiter as to allow the development of successful numerical algorithms. The main goal of this paper is to identify new less restrictive sufficient conditions for flux form in-compressible advection to remain monotonic. We identify additional necessary conditions for incompressible flux form advection to be monotonic, demonstrating that the Spekreijse limiter region is not sufficient for incompressible flux form advection to remain monotonic. Then a convex combination argument is used to derive new sufficient conditions that are less restrictive than the Sweby region for a discrete maximum principle. This allows the introduction of two new more general limiter regions suitable for flux form incompressible advection.
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- 2024
32. Data assimilation for the stochastic Camassa-Holm equation using particle filtering: a numerical investigation
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Cotter, Colin John, Crisan, Dan, and Singh, Maneesh Kumar
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Mathematics - Numerical Analysis - Abstract
In this study, we explore data assimilation for the Stochastic Camassa-Holm equation through the application of the particle filtering framework. Specifically, our approach integrates adaptive tempering, jittering, and nudging techniques to construct an advanced particle filtering system. All filtering processes are executed utilizing ensemble parallelism. We conduct extensive numerical experiments across various scenarios of the Stochastic Camassa-Holm model with transport noise and viscosity to examine the impact of different filtering procedures on the performance of the data assimilation process. Our analysis focuses on how observational data and the data assimilation step influence the accuracy and uncertainty of the obtained results., Comment: Submitted for STUOD 2024 volume
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- 2024
33. Acceleration and transport of relativistic electrons in the jets of the microquasar SS 433
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Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaou, M., Breuhau, M., Brose, R., Brown, A. M., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Caroff, S., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Dai, S., Mbarubucyeye, J. Damascene, Djannati-Ataï, A., Dmytriiev, A., Doroshenko, V., Egberts, K., Einecke, S., Ernenwein, J. -P., Filipovic, M., Fontaine, G., Funk, S., Gabici, S., Ghafourizadeh, S., Giavitto, G., Glawion, D., Glicenstein, J. F., Grolleron, G., Haerer, L., Hinton, J. A., Hofmann, W., Holch, T. L., Holler, M., Horns, D., Jamrozy, M., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Khatoon, R., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lenain, J. -P., Leuschner, F., Lohse, T., Luashvili, A., Mackey, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Martí-Devesa, G., Marx, R., Mehta, A., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., Nakashima, K., de Naurois, M., Niemiec, J., Noel, A. Priyana, Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Prokhorov, D. A., Pühlhofer, G., Punch, M., Quirrenbach, A., Reichherzer, P., Reimer, A., Reimer, O., Ren, H., Renaud, M., Reville, B., Rieger, F., Rowell, G., Rudak, B., Ricarte, H. Rueda, Ruiz-Velasco, E., Sahakian, V., Salzman, H., Santangelo, A., Sasaki, M., Schäfer, J., Schüssler, F., Schwanke, U., Shapopi, J. N. S., Sol, H., Specovius, A., Spencer, S., Stawarz, Ł., Steenkamp, R., Steinmassl, S., Steppa, C., Streil, K., Sushch, I., Suzuki, H., Takahashi, T., Tanaka, T., Taylor, A. M., Terrier, R., Tsirou, M., Tsuji, N., Unbehaun, T., van Eldik, C., Vecchi, M., Veh, J., Venter, C., Vink, J., Wach, T., Wagner, S. J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Zacharias, M., Zargaryan, D., Zdziarski, A. A., Zech, A., Zouari, S., and Żywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
SS 433 is a microquasar, a stellar binary system with collimated relativistic jets. We observed SS 433 in gamma rays using the High Energy Stereoscopic System (H.E.S.S.), finding an energy-dependent shift in the apparent position of the gamma-ray emission of the parsec-scale jets. These observations trace the energetic electron population and indicate the gamma rays are produced by inverse-Compton scattering. Modelling of the energy-dependent gamma-ray morphology constrains the location of particle acceleration and requires an abrupt deceleration of the jet flow. We infer the presence of shocks on either side of the binary system at distances of 25 to 30 parsecs and conclude that self-collimation of the precessing jets forms the shocks, which then efficiently accelerate electrons., Comment: Submitted 20th Apr. 2023, published 25th January 2024 (accepted version)
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- 2024
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34. 'I Got Flagged for Supposed Bullying, Even Though It Was in Response to Someone Harassing Me About My Disability.': A Study of Blind TikTokers' Content Moderation Experiences
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Lyu, Yao, Cai, Jie, Callis, Anisa, Cotter, Kelley, and Carroll, John M.
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Computer Science - Human-Computer Interaction - Abstract
The Human-Computer Interaction (HCI) community has consistently focused on the experiences of users moderated by social media platforms. Recently, scholars have noticed that moderation practices could perpetuate biases, resulting in the marginalization of user groups undergoing moderation. However, most studies have primarily addressed marginalization related to issues such as racism or sexism, with little attention given to the experiences of people with disabilities. In this paper, we present a study on the moderation experiences of blind users on TikTok, also known as "BlindToker," to address this gap. We conducted semi-structured interviews with 20 BlindTokers and used thematic analysis to analyze the data. Two main themes emerged: BlindTokers' situated content moderation experiences and their reactions to content moderation. We reported on the lack of accessibility on TikTok's platform, contributing to the moderation and marginalization of BlindTokers. Additionally, we discovered instances of harassment from trolls that prompted BlindTokers to respond with harsh language, triggering further moderation. We discussed these findings in the context of the literature on moderation, marginalization, and transformative justice, seeking solutions to address such issues., Comment: 24 paged, 1 Figure, accepted by CHI'24
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- 2024
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35. Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study.
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Pondicherry, Neha, Abdou, Amza, Kadri, Boubacar, Nassirou, Beido, Cotter, Sun, Varnado, Nicole, Porco, Travis, West, Sheila, Lietman, Thomas, and Keenan, Jeremy
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Azithromycin ,Humans ,Anti-Bacterial Agents ,Child ,Preschool ,Infant ,Female ,Trachoma ,Male ,Longitudinal Studies ,Chlamydia trachomatis ,Treatment Outcome ,Chlamydia Infections ,Niger ,Infant ,Newborn - Abstract
Millions of doses of azithromycin are distributed each year for trachoma, yet the treatment efficacy of a single dose of azithromycin for ocular Chlamydia infection has not been well characterized. In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-monthly monitoring schedule was suboptimal for testing the treatment efficacy of an antibiotic, these findings are nonetheless consistent with high treatment efficacy of a single dose of azithromycin and suggest that additional interventions might be most effective if targeted to those children infected prior to treatment.
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- 2024
36. Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study.
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Byrne, Jonah, Healy, Colm, Föcking, Melanie, Susai, Subash, Mongan, David, Wynne, Kieran, Kodosaki, Eleftheria, Heurich, Meike, de Haan, Lieuwe, Hickie, Ian, Smesny, Stefan, Thompson, Andrew, Markulev, Connie, Young, Alison, Schäfer, Miriam, Riecher-Rössler, Anita, Mossaheb, Nilufar, Berger, Gregor, Schlögelhofer, Monika, Nordentoft, Merete, Chen, Eric, Verma, Swapna, Nieman, Dorien, Woods, Scott, Cornblatt, Barbara, Stone, William, Addington, Jean, Walker, Elaine, Cannon, Tyrone, Cannon, Mary, McGorry, Pat, Amminger, Paul, Cagney, Gerard, Nelson, Barnaby, Jeffries, Clark, Perkins, Diana, Cotter, David, Mathalon, Daniel, Bearden, Carrie, and Cadenhead, Kristin
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coagulation ,complement ,high risk ,immune ,model ,prediction ,proteome ,psychosis ,Humans ,Psychotic Disorders ,Female ,Male ,Biomarkers ,Proteomics ,Young Adult ,Adolescent ,Prodromal Symptoms ,Adult ,Disease Progression ,Longitudinal Studies ,Risk - Abstract
Psychosis risk prediction is one of the leading challenges in psychiatry. Previous investigations have suggested that plasma proteomic data may be useful in accurately predicting transition to psychosis in individuals at clinical high risk (CHR). We hypothesized that an a priori-specified proteomic prediction model would have strong predictive accuracy for psychosis risk and aimed to replicate longitudinal associations between plasma proteins and transition to psychosis. This study used plasma samples from participants in 3 CHR cohorts: the North American Prodrome Longitudinal Studies 2 and 3, and the NEURAPRO randomized control trial (total n = 754). Plasma proteomic data were quantified using mass spectrometry. The primary outcome was transition to psychosis over the study follow-up period. Logistic regression models were internally validated, and optimism-corrected performance metrics derived with a bootstrap procedure. In the overall sample of CHR participants (age: 18.5, SD: 3.9; 51.9% male), 20.4% (n = 154) developed psychosis within 4.4 years. The a priori-specified model showed poor risk-prediction accuracy for the development of psychosis (C-statistic: 0.51 [95% CI: 0.50, 0.59], calibration slope: 0.45). At a group level, Complement C8B, C4B, C5, and leucine-rich α-2 glycoprotein 1 (LRG1) were associated with transition to psychosis but did not surpass correction for multiple comparisons. This study did not confirm the findings from a previous proteomic prediction model of transition from CHR to psychosis. Certain complement proteins may be weakly associated with transition at a group level. Previous findings, derived from small samples, should be interpreted with caution.
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- 2024
37. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis.
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Wannan, Cassandra, Nelson, Barnaby, Addington, Jean, Allott, Kelly, Anticevic, Alan, Arango, Celso, Baker, Justin, McGorry, Patrick, Mittal, Vijay, Nordentoft, Merete, Nunez, Angela, Pasternak, Ofer, Pearlson, Godfrey, Perez, Jesus, Perkins, Diana, Powers, Albert, Roalf, David, Sabb, Fred, Schiffman, Jason, Shah, Jai, Smesny, Stefan, Spark, Jessica, Stone, William, Strauss, Gregory, Tamayo, Zailyn, Torous, John, Upthegrove, Rachel, Vangel, Mark, Verma, Swapna, Wang, Jijun, Rossum, Inge, Wolf, Daniel, Wolff, Phillip, Wood, Stephen, Yung, Alison, Agurto, Carla, Alvarez-Jimenez, Mario, Amminger, Paul, Armando, Marco, Asgari-Targhi, Ameneh, Cahill, John, Carrión, Ricardo, Castro, Eduardo, Cetin-Karayumak, Suheyla, Mallar Chakravarty, M, Cho, Youngsun, Cotter, David, DAlfonso, Simon, Ennis, Michaela, Fadnavis, Shreyas, Fonteneau, Clara, Gao, Caroline, Gupta, Tina, Gur, Raquel, Gur, Ruben, Hamilton, Holly, Hoftman, Gil, Jacobs, Grace, Jarcho, Johanna, Ji, Jie, Kohler, Christian, Lalousis, Paris, Lavoie, Suzie, Lepage, Martin, Liebenthal, Einat, Mervis, Josh, Murty, Vishnu, Nicholas, Spero, Ning, Lipeng, Penzel, Nora, Poldrack, Russell, Polosecki, Pablo, Pratt, Danielle, Rabin, Rachel, Rahimi Eichi, Habiballah, Rathi, Yogesh, Reichenberg, Avraham, Reinen, Jenna, Rogers, Jack, Ruiz-Yu, Bernalyn, Scott, Isabelle, Seitz-Holland, Johanna, Srihari, Vinod, Srivastava, Agrima, Thompson, Andrew, Turetsky, Bruce, Walsh, Barbara, Whitford, Thomas, Wigman, Johanna, Yao, Beier, Yuen, Hok, Ahmed, Uzair, Byun, Andrew, Chung, Yoonho, Do, Kim, Hendricks, Larry, Huynh, Kevin, Jeffries, Clark, Lane, Erlend, and Langholm, Carsten
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clinical high risk ,consortium ,early detection ,prediction ,prevention ,psychosis ,Humans ,Psychotic Disorders ,Schizophrenia ,Prospective Studies ,Adult ,Prodromal Symptoms ,Young Adult ,International Cooperation ,Adolescent ,Research Design ,Male ,Female - Abstract
This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community. In an expected sample of approximately 2000 CHR individuals and 640 matched healthy controls, AMP SCZ will collect clinical, environmental, and cognitive data along with multimodal biomarkers, including neuroimaging, electrophysiology, fluid biospecimens, speech and facial expression samples, novel measures derived from digital health technologies including smartphone-based daily surveys, and passive sensing as well as actigraphy. The study will investigate a range of clinical outcomes over a 2-year period, including transition to psychosis, remission or persistence of CHR status, attenuated positive symptoms, persistent negative symptoms, mood and anxiety symptoms, and psychosocial functioning. The global reach of AMP SCZ and its harmonized innovative methods promise to catalyze the development of new treatments to address critical unmet clinical and public health needs in CHR individuals.
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- 2024
38. Prevalence of Comprehensive Eye Examination in Preschool Children With Eye Conditions
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Yu, Victoria K, Tarczy-Hornoch, Kristina, Cotter, Susan A, Torres, Mina, Jiang, Xuejuan, and Varma, Rohit
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Allied Health and Rehabilitation Science ,Biomedical and Clinical Sciences ,Health Sciences ,Ophthalmology and Optometry ,Neurosciences ,Clinical Research ,Pediatric ,Brain Disorders ,Eye Disease and Disorders of Vision ,Prevention ,Eye ,Amblyopia ,comprehensive eye examination ,preschool vision screening ,refractive error ,strabismus - Abstract
IntroductionThe purpose of this study is to assess the prevalence of comprehensive eye examinations in multiethnic preschool children, including children with visually significant eye conditions, and identify factors associated with comprehensive eye examinations.MethodsA sample of 9,197 African American, Hispanic, Asian American, and non-Hispanic White children aged 6-72 months was recruited for the Multi-Ethnic Pediatric Eye Disease Study from 2003 to 2011. Logistic regression performed in 2022 identified independent factors associated with parent-reported history of comprehensive eye examinations. The proportion of children with previous comprehensive eye examinations and the proportion with undetected amblyopia or strabismus were measured.ResultsThe prevalence of comprehensive eye examinations was 6.3% overall and 38.3%, 24.8%, 19.1%, 15.1%, and 9.8% among children with strabismus, amblyopia, significant anisometropia, hyperopia, and astigmatism, respectively. Children without prior comprehensive eye examinations were more likely to have undetected amblyopia or strabismus than those with comprehensive eye examination history (ps
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- 2024
39. Bi-planar magnetic stabilisation coils for an inertial sensor based on atom interferometry
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Davis, A., Hobson, P. J., Smith, T. X., Morley, C., Sewell, H. G., Cotter, J., and Fromhold, T. M.
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Physics - Atomic Physics ,Mathematical Physics ,Physics - Instrumentation and Detectors - Abstract
Inertial sensors that measure the acceleration of ultracold atoms promise unrivalled accuracy compared to classical equivalents. However, atomic systems are sensitive to various perturbations, including magnetic fields, which can introduce measurement inaccuracies. To address this challenge, we have designed, manufactured, and validated a magnetic field stabilisation system for a quantum sensor based on atom interferometry. We solve for the magnetic field generated by surface currents in-between a pair of rectangular coils and approximate the surface current using discrete wires. The wires are wound by-hand onto machined panels which are retrofitted onto the existing mounting structure of the sensor without interfering with any experimental components. Along the central $60$ mm of the $y$-axis, which aligns with the trajectory of the atoms during interferometry, the coils are measured to generate an independent uniform axial magnetic field with a strength of $B_z=\left(22.81\pm0.01\right)$ $\mu$T/A [$\mathrm{mean}\pm2\sigma\mathrm{std. error}$] and an independent linear axial field gradient of strength $\mathrm{d}B_z/\mathrm{d}y=\left(10.6\pm0.1\right)$ $\mu$T/Am. The uniform $B_z$ field is measured to deviate by a maximum value of $1.3$% in the same region, which is a factor of three times more uniform than the previously-used on-sensor rectangular $B_z$ compensation set., Comment: 11 pages, 9 figures
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- 2023
40. Aspire2Health and covid-19: The impact of the pandemic on outcomes from an outreach program to increase high school student interest in rural health careers
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MacAskill, William, Fallon, Anthony Bruce, Cotter, Nicola, and Purea, Paul
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- 2023
41. Sustained Strain: Faculty Work Strain Under COVID-19
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Cotter, David A., Berheide, Catherine White, and Carpenter, Megan A.
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- 2024
- Full Text
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42. The Effect of the COVID-19 Pandemic on Faculty Well-being: A Study of Academic Staff at Three Colleges in New York State
- Author
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Berheide, Catherine White, Carpenter, Megan A., Cotter, David A., Michalos, Alex C., Series Editor, Møller, Valerie, Editorial Board Member, Glatzer, Wolfgang, Editorial Board Member, Moum, Torbjorn, Editorial Board Member, Veenhoven, Ruut, Editorial Board Member, Suter, Christian, editor, Chesters, Jenny, editor, and Fachelli, Sandra, editor
- Published
- 2025
- Full Text
- View/download PDF
43. Data Assimilation for the Stochastic Camassa-Holm Equation Using Particle Filtering: A Numerical Investigation
- Author
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Cotter, Colin J., Crisan, Dan, Singh, Maneesh Kumar, Crisan, Dan, Series Editor, Golden, Ken, Series Editor, Holm, Darryl D., Series Editor, Lewis, Mark, Series Editor, Nishiura, Yasumasa, Series Editor, Tribbia, Joseph, Series Editor, Zubelli, Jorge Passamani, Series Editor, Chapron, Bertrand, editor, Mémin, Etienne, editor, and Coughlan, Jane-Lisa, editor
- Published
- 2025
- Full Text
- View/download PDF
44. Evaluation of mAb 2C5-modified dendrimer-based micelles for the co-delivery of siRNA and chemotherapeutic drug in xenograft mice model
- Author
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Yalamarty, Satya Siva Kishan, Filipczak, Nina, Pathrikar, Tanvi, Cotter, Colin, Ataide, Janaína Artem, Luther, Ed, Paranjape, Swarali, and Torchilin, Vladimir
- Published
- 2024
- Full Text
- View/download PDF
45. Within-Person Fluctuations in Objective Smartphone Use and Emotional Processes During Adolescence: An Intensive Longitudinal Study
- Author
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Rodman, Alexandra M., Burns, Jason A., Cotter, Grace K., Ohashi, Yuri-Grace B., Rich, Rachael K., and McLaughlin, Katie A.
- Published
- 2024
- Full Text
- View/download PDF
46. Cardiovascular disease risk assessment in patients with rheumatoid arthritis: A scoping review
- Author
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Murphy, Louise, Saab, Mohamad M., Cornally, Nicola, McHugh, Sheena, and Cotter, Patrick
- Published
- 2024
- Full Text
- View/download PDF
47. Species diversity and extinction risk of vertebrate pollinators in India
- Author
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Kallivalappil, Ratheesh, Grattarola, Florencia, de Alwis Pitts, Dilkushi, Cotter, Sheena C., and Pincheira-Donoso, Daniel
- Published
- 2024
- Full Text
- View/download PDF
48. Intraoperative Echocardiography: Guide to Decision-Making
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Cutrone, Michael, Cotter, Sarah, Swaminathan, Madhav, and McCartney, Sharon
- Published
- 2024
- Full Text
- View/download PDF
49. Engaging Faith-Based Organizations to Promote Health Through Health Ministries in Washington, DC
- Author
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Wells, Ayanna, McClave, Robin, Cotter, Elizabeth W., Pruski, Tom, Nix, Deborah, and Snelling, Anastasia M.
- Published
- 2024
- Full Text
- View/download PDF
50. Investigating the Lorentz Invariance Violation effect using different cosmological backgrounds
- Author
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Abdalla, Hassan, Cotter, Garret, Backes, Michael, Kasai, Eli, and Böttcher, Markus
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
Familiar concepts in physics, such as Lorentz symmetry, are expected to be broken at energies approaching the Planck energy scale as predicted by several quantum-gravity theories. However, such very large energies are unreachable by current experiments on Earth. Current and future Cherenkov telescope facilities may have the capability to measure the accumulated deformation from Lorentz symmetry for photons traveling over large distances via energy-dependent time delays. One of the best natural laboratories to test Lorentz Invariance Violation~(LIV) signatures are Gamma-ray bursts~(GRBs). The calculation of time delays due to the LIV effect depends on the cosmic expansion history. In most of the previous works calculating time lags due to the LIV effect, the standard $\Lambda$CDM (or concordance) cosmological model is assumed. In this paper, we investigate whether the LIV signature is significantly different when assuming alternatives to the $\Lambda$CDM cosmological model. Specifically, we consider cosmological models with a non-trivial dark-energy equation of state ($w \neq -1$), such as the standard Chevallier-Polarski-Linder~(CPL) parameterization, the quadratic parameterization of the dark-energy equation of state, and the Pade parameterizations. We find that the relative difference in the predicted time lags is small, of the order of at most a few percent, and thus likely smaller than the systematic errors of possible measurements currently or in the near future., Comment: Accepted for publication in Class. Quantum Grav., 10 pages, 1 figure
- Published
- 2023
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