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Le «nove canzoni» di Gian Francesco Malipiero sono, per ammissione dell’autore stesso, da identificarsi con le tre opere malipieriane Le tre poesie di Angelo Poliziano (1920), i Quattro sonetti del Burchiello (1921) e i Due sonetti del Berni (1922). Queste canzoni per voce e pianoforte appartengono al filone culturale che aveva posto le basi per il recupero dell’antico, divenuto la cosiddetta “missione storica” della generazione dell’Ottanta. Il percorso didattico, rivolto agli studenti del secondo biennio della Scuola secondaria di secondo grado, parte da un’analisi morfologica del testo verbale, da confrontarsi con quella del testo musicale, e prosegue con la ricerca delle soluzioni adottate da Malipiero per valorizzare l’antica tradizione italiana attraverso le interazioni tra musica e letteratura. Le attività proposte, basate sull’ascolto correlato all’analisi del testo poetico, mirano a favorire i diversi collegamenti interdisciplinari offerti dalle «nove canzoni»., Musica Docta, Vol. 12 (2022)

Aim: To determine the current burden of MS in Sardinia, insular Italy, a region at high risk for the disease. Methods: Age- and gender-specific population-based prevalence and incidence were updated based on data from 40-year MS surveillance in the study area (provinces of Sassari and Olbia-Tempio, pop. 481,000 ca). Medical records and district health statistics (hospital discharge ICD9-CM and ticket exemption codes) were scrutinized for the study population. Estimates were based on MS according to Poser et al. criteria. Results: On prevalence day, December 31st 2008, 1265 individuals suffering from MS (345 men, 920 women) were living in the study area. Crude total prevalence was 260.3 per 100,000 (95%CIs: 256,3-264,3), 144,5 and 372,2 for men and women, respectively. The respective estimates adjusted for the 2008 Italian population were 247,6, 137,8, 353.2. Prevalence significantly increased from 1971 (13.6) to 2008. Mean age at death also increased from 40.6 (1971) to 58.7 (2008) years (no gender effect). Mean total incidence for the period 2000-4 was 10.5 per 100,000/year (95%CIs: 8.1, 12.4), 6.3 for men, 14.5 for women. In 1965-2008, mean age at clinical onset increased from 25.5 to 32.1 years with no gender effect; F:M ratio increased from 1.54 to 2.90 Conclusions: MS burden in Sardinia, insular Italy is to our knowledge the highest worldwide. MS in Sardinians shows a relevant incremental temporal trend of prevalence that can be explained by increasing survival but remarkably by increasing incidence especially in women. Because such variation has occurred within a relatively short period of time in this genetically stable population, a corrisponding change in the temporal distribution of an enviromental factor(s) and/or in the population’s lifestyle deserves further investigation.

In recent years the European Commission has increasingly focused its attention on the development of sustainable city logistics by promulgating legislation and formal directives. Despite the efforts made, reducing freight-related congestion and polluting emissions without penalising social and economic activities within cities is still a challenging issue. City logistics measures frequently fail mainly due to a lack of support and commitment from stakeholders. A participatory approach in freight transport planning represents a reasonable and valuable option. This paper describes the innovative governance model developed in the city of Turin in Italy that was based on a proactive and effective stakeholders' cooperation for achieving a resilient urban development. The added value of the paper also relates to the real-life assessment of the impacts the non-mandatory policy-mix implemented, based on a collaborative governance model, have on the environment and service delivery thus providing a realistic measure of the viability and effectiveness of the solution proposed. Its voluntary adoption, in fact, produces an increase in commercial vehicles’ speed and a substantial reduction in CO 2 emissions while also allowing logistic service providers to perform more deliveries.

It has been recently reported that a large proportion of patients with familial amyotrophic lateral sclerosis (familial ALS) and frontotemporal dementia (FTD) are associated with a hexanucleotide (GGGGCC) repeat expansion in the first intron of C9ORF72. We have assessed 1,757 Italian sporadic ALS cases, 133 from Sardinia, 101 from Sicily, and 1,523 from mainland Italy. Sixty (3.7%) of 1,624 mainland Italians and Sicilians and 9 (6.8%) of the 133 Sardinian sporadic ALS cases carried the pathogenic repeat expansion. None of the 619 regionally-matched control samples (1,238 chromosomes) carried the expansion. Twenty-five cases (36.2%) had behavioral FTD in addition to ALS. FTD or unspecified dementia was also detected in 19 pedigrees (27.5%) in first-degree relatives of ALS patients. Cases carrying the C9ORF72 hexanucleotide expansion survived one year less than cases who did not carry this mutation. In conclusion, we found that C9ORF72 hexanucloetide repeat expansions represents a sizeable proportion of apparent sporadic ALS in the Italian and Sardinian population, representing by far the commonest mutation in Italy and the second more common in Sardinia.