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1. The Production of High-Density Briquettes from Wheat Chaff for Energy and Livestock Use

Author

Calegari, F., Bisaglia, C., Assirelli, A., Corvi, G., Moschini, E., Piccioli Cappelli, F., and Masoero, F.

Subjects
Biomass
Abstract

With a view to circular economy and environmental sustainability about the possible alternative uses of by-products from the cultivation of winter cereals, the chaff of soft wheat from an experimental plot located in the province of Lodi, Italy, was sent to a briquette pressing plant to assess the feasibility of producing high-density briquettes to make logistics more economical and provide farmers with a range of viable options. A prototype of chaff/straw separator applied as a retrofit to a commercial combine harvester with a conventional threshing apparatus was purpose designed and used. Energy and livestock alternative applications were identified and analyzed. The preliminary results were of interest: the density of the processed biomass was 4.4 times higher than that of the raw material suggesting good conditions of trasportability for medium-short range energy purposes, while from the point of view of their use as litter in cow barns cubicles, a slight preference of dairy cows over sawdust bedding was recorded., Proceedings of the 30th European Biomass Conference and Exhibition, 9-12 May 2022, Online, pp. 756-760

Published
2022
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6. COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

Author

ALTMAN, R, CARRERAS, L, DIAZ, R, FIGUEROA, E, PAOLASSO, E, PARODI, J, CADE, J, DONNAN, G, EADIE, M, GAVAGHAN, T, OSULLIVAN, E, PARKIN, D, RENNY, J, SILAGY, C, VINAZZER, H, ZEKERT, F, ADRIAENSEN, H, BERTRANDHARDY, J, BRAN, M, DAVID, J, DRICOT, J, LAVENNEPARDONGE, E, LIMET, R, LOWENTHAL, A, MORIAU, M, SCHAPIRA, S, SMETS, P, SYMOENS, J, VERHAEGHE, R, VERSTRAETE, M, ATALLAH, A, BARNETT, H, BATISTA, R, BLAKELY, J, CAIRNS, J, COTE, R, CROUCH, J, EVANS, G, FINDLAY, J, GENT, M, LANGLOIS, Y, LECLERC, J, NORRIS, J, PINEO, G, POWERS, P, ROBERTS, R, SCHWARTZ, L, SICURELLA, J, TAYLOR, W, THEROUX, P, TURPIE, A, WEISEL, R, CUI, J, LIU, L, PIRK, J, BAY, C, BOYSEN, G, KNUDSEN, J, PETERSEN, P, SORENSEN, P, TONNESEN, H, HARJOLA, P, ARCAN, J, BALKAU, B, BLANCHARD, J, BOISSEL, J, BONEU, B, BOUSSER, M, BROCHIER, M, CLOAREC, M, CRIBIER, G, DECHAVANNE, M, DROUIN, P, ESCHWEGE, E, GUIRAUDCHAUMEIL, B, HUGONOT, R, LEIZOROVICZ, A, LORIA, Y, MICHAT, L, MIROUZE, J, PANAK, E, PASTEYER, J, RASCOL, A, REVOL, L, ROY, M, SELLES, J, SLAMA, G, STARKMAN, C, TEULE, M, THIBULT, N, VERRY, M, ALBERT, F, ANDRASSY, K, BREDDIN, K, ECKEL, R, ENCKE, A, FROHLICH, J, HARTUNG, B, HEISS, H, HESS, H, HOFLING, B, KRAUSE, D, LATTA, G, LINKE, H, LOEW, D, LORENZ, R, MIDDLETON, K, NOVAK, G, OLDENDORF, M, PFLUGER, N, RAITHEL, D, REUTER, R, SCHETTLER, G, SCHNITKER, J, SCHOOP, W, STIEGLER, H, UBERLA, K, VOGEL, G, WEBER, M, WELBERS, I, ZEITLER, E, ARAPAKIS, G, CHAN, T, MOK, C, SZABO, R, MISRA, N, REDDY, K, FITZGERALD, G, APOLLONIO, A, BALSANO, F, BASELLINI, A, CANDELISE, L, CATALANO, M, CIAVARELLA, N, CIUFFETTI, G, COCCHERI, S, CORTELLARO, M, CORVI, G, COTO, V, DAVI, G, DECATERINA, R, DIPERRI, T, FIESCHI, C, GENTILE, R, GREGORATTI, L, GRESELE, P, LAVEZZARI, M, LIBRETTI, A, MAGNANI, B, NENCI, G, PAGANO, G, PATRONO, C, PEDRINI, L, PINI, M, PRANDONI, P, ROMEO, F, ROVELLI, F, RUDELLI, G, RUVOLO, G, SIGNORINI, G, TOGNONI, G, VIOLI, F, FUJIMORI, T, KAGEYAMA, M, KATSUMURA, T, KITAMURA, S, MAEDA, K, SUZUKI, A, TOHGI, H, UCHIYAMA, S, UTSUMI, H, GARCIA, A, ALGRA, A, DENOTTOLANDER, G, KUPPER, A, VANGIJN, J, HART, H, KAPPELLE, L, KOUDSTAAL, P, LEMMENS, T, LODDER, J, PANNEBAKKER, M, SERRUYS, P, VANDENBELT, A, VANDERMEER, J, VANDERVIJGH, A, VERHEUGT, F, VETH, G, DALE, J, JOHANNESSEN, K, THAULOW, E, POPESCU, P, TIBERIU, N, AZNAR, J, ESMATJES, E, GUITERAS, P, LASIERRA, J, LOPEZTRIGO, P, ORIOL, A, POMAR, L, ROCHA, E, SANCHEZ, F, SANCHORIEGER, J, SANZ, G, BERGLUND, U, BLOMSTRAND, C, BOBERG, M, BRITTON, M, ELWIN, C, HELMERS, C, HOLM, J, JANZON, L, JUULMOLLER, S, MULEC, H, OLSSON, J, PERSSON, S, RASMANIS, G, ROSEN, A, SAMUELSSON, K, SOREFF, J, WAHLGREN, N, WALLENTIN, L, BAUR, H, BOKSLAG, M, BOLLINGER, A, MEIER, B, PFISTERER, M, SITTHIAMORN, C, ACHESON, E, APPLEBY, P, ASSCHER, A, AUKLAND, A, BAIGENT, C, BALA, S, BARNETT, A, BELL, P, BEWS, S, BORN, G, BRANAGAN, J, BROOKS, N, BROWN, M, BROWSE, N, CAPILDEO, R, CARMALT, M, CARTER, A, CHALMERS, I, CLARKE, M, CLARKE, R, CLYNE, C, COLLINS, R, COOKE, E, COUTTS, G, COVE, D, CROWTHER, P, CUTHBERTSON, W, DEBONO, D, DICKERSON, C, DICKINSON, J, DOLL, R, DORMANDY, J, DUNBABIN, D, ELL, S, ELPHINSTONE, P, ELWOOD, P, ENGLISHBY, V, FARRELL, B, FISKERSTRAND, C, FLATHER, M, FOLEY, T, FOULDS, T, FOX, K, FRANKS, P, FRASER, H, GARDECKI, T, GAWEL, M, GENT, A, GERSHLICK, A, GODWIN, J, GOLDMAN, M, GRAY, C, GRAY, D, GRAY, R, HANDOLL, H, HANKEY, G, HARRISON, M, HENDERSON, N, HEPTINSTALL, S, HOBBIGER, S, JONES, E, JONES, N, JOST, S, JULIAN, D, KELLETT, J, KESTER, R, LOWE, G, MACKENZIE, J, MCCOLLUM, C, MEAD, G, MEADE, T, MENDELOW, D, MILLER, J, MORRIS, G, NICHOL, C, NOBLE, M, OBRIEN, J, OGIER, M, PARISH, S, PARRY, M, PETO, R, POWELL, J, POZZILLI, P, QIZILBASH, N, RAHMAN, A, RAJAH, S, RICHARDS, D, RICHARDS, S, RIPLEY, R, ROBERTS, V, ROSE, F, RUSSELL, R, RUBIN, P, RUCKLEY, C, SANDERCOCK, P, SHAW, M, SHAW, K, SHELLEY, J, SLATTERY, J, SLEIGHT, P, SMITH, S, STEWARTLONG, P, SWEETNAM, P, TANSEY, M, TINDALL, H, TURNEY, J, TYLER, H, VAREY, N, VESSEY, M, WALKER, M, WARLOW, C, WILCOX, R, WILLEMS, H, WOOD, E, WYNJONES, E, ADAMS, H, BARTON, B, BEDFORD, R, BICK, B, BINGHAM, S, BROWN, B, BRYANT, T, BURING, J, CABOT, C, CANNER, P, CHESEBRO, J, CHRISMAN, O, CLAGETT, G, COLWELL, J, DYKEN, M, ELLIS, D, FIELDS, W, FURBERG, C, FUSTER, V, GOLDMAN, S, GRANETT, J, GREEN, R, GREEN, D, HARDY, R, HARKER, L, HARRIS, W, HART, R, HASS, W, HENNEKENS, C, HILL, D, HUME, M, IGLOE, M, JOHNSON, G, JONAS, S, KNATTERUD, G, KOHLER, T, LEMBO, N, LEWIS, D, LOCKHART, E, MAJERUS, P, MCENANY, M, MCKENNA, R, MEHTA, J, MEYER, J, MOLONY, B, MORITZ, T, NICOLOFF, D, NYCZ, G, ONO, H, PANTELY, G, PHILLIPS, S, RIDKER, P, ROBERTSON, J, ROTHBART, R, SALZMAN, E, SAUTTER, R, SCHLANT, R, SCHOENBERGER, J, SENGEKONTACKET, M, SHARMA, G, STEELE, P, STEINNAGEL, K, STRATTON, J, SULLIVAN, J, TIMMIS, G, TOOLE, J, WEISMAN, S, WHITE, C, WIRECKI, M, WOMBOLT, D, WONG, R, YUSUF, S, ZADINA, K, and ZUCKER, D

Published
1994

7. Gastro-Intestinal Blood Loss during Administration of Indoprofen, Aspirin and Ibuprofen

Author

Porro, G Bianchi, Corvi, G, Fuccella, L M, Goldaniga, G C, and Valzelli, G

Abstract

The acute effect of three non-steroidal anti-inflammatory drugs, ibuprofen, acetylsalicylic acid (ASA) and indoprofen, on faecal blood loss was investigated in 15 subjects by means of 51Cr-labelled erythrocytes.Ibuprofen (900 mg/day for 5 days) and indoprofen capsules and tablets (300 mg and 600 mg/day for 5 days, respectively) slightly increased the amount of blood eliminated in faeces. The increase was of the same order of magnitude for both doses of indoprofen. ASA (1,500 mg/day for 5 days) caused about a 6-fold increase in blood loss. Four days after withdrawal of ASA, faecal blood was still about twice as high as in faeces of subjects given ibuprofen and indoprofen.The method appears sensitive and reliable for comparison of the immediate effect of anti-inflammatory drugs on gastrointestinal mucosa.

Published
1977
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8. Inhibition of Platelet Aggregation in Man by Indobufen (K 3920)

Author

Vittoria, A, Pasini, F Laghi, Messa, G L, Di Perri, T, Corvi, G, and Fuccella, LM

Abstract

A complete crossover trial was undertaken in six healthy volunteers to gain information on dose-effect responses to indobufen by assessing the intensity and duration of the effect of 3 single oral doses of the drug on platelet aggregation induced by threshold concentration of ADP and by 3 added doses of collagen.The results of the study confirm that the activity is dose-related and is reversible since 24 hours after administration it has practically disappeared. The effect of the same dose of indobufen differed significantly according to the amount of collagen added to plasma, whereas increasing doses of indobufen provoked a significantly more marked effect when the amount of inducer employed was the same.

Published
1981
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9. Prevention of in vivoPlatelet Aggregation by Indobufen in Angina Patients during Exercise

Author

Pogliani, E M, Fantasia, R, Perini, C, and Corvi, G

Abstract

Platelet aggregation induced by 3 concentrations of ADP and collagen was assessed in thirty patients with stable angina, before and after exercise with a bicycle ergometer. The patients received a single oral 200 mg dose of indobufen and placebo according to a crossover design in double-blind conditions. Platelet sensitivity to both aggregating agents increased when exercise was carried out after placebo, whereas indobufen markedly inhibited ADP- and collagen-induced aggregation. Circulating platelet aggregates increased in some patients during exercise after placebo but not after indobufen. These results suggest that effort may be an important factor in activation of platelet functions and that the use of drugs blocking the arachidonate pathway and the release reaction may be appropriate in patients with angina.

Published
1981
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14. Controlling the Formation of Peptide Films: Fully Developed Helical Peptides are Required to Obtain a Homogenous Coating over a Large Area.

Author

De Zotti M, Corvi G, Gatto E, Di Napoli B, Mazzuca C, Palleschi A, Placidi E, Biondi B, Crisma M, Formaggio F, Toniolo C, and Venanzi M

Subjects
Amino Acid Sequence, Microscopy, Atomic Force, Molecular Dynamics Simulation, Surface Properties, Water chemistry, X-Ray Diffraction, Aluminum Silicates chemistry, Graphite chemistry, Lipopeptides chemistry, Nanostructures chemistry
Abstract

The influence of conformational dynamics on the self-assembly process of a conformationally constrained analogue of the natural antimicrobial peptide Trichogin GA IV was analysed by spectroscopic methods, microscopy imaging at nanometre resolution, and molecular dynamics simulations. The formation of peptide films at the air/water interface and their deposition on a graphite or a mica substrate were investigated. A combination of experimental evidence with molecular dynamics simulation was used to demonstrate that only the fully developed helical structure of the analogue promotes formation of ordered aggregates that nucleate the growth of micrometric rods, which give rise to homogenous coating over wide regions of the hydrophilic mica. This work proves the influence of helix flexibility on peptide self-organization and orientation on surfaces, key steps in the design of bioinspired organic/inorganic hybrid materials., (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2019
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16. Application of nonparametric procedure for bioassay data to the evaluation of analgesics in man.

Author

Fuccella LM, Corvi G, Gorini F, Mandelli V, Mascellani G, Nobili F, Pedronetto S, Ragni N, and Vandelli I

Subjects
Adolescent, Adult, Analgesics adverse effects, Analgesics therapeutic use, Aspirin adverse effects, Aspirin therapeutic use, Clinical Trials as Topic, Dose-Response Relationship, Drug, Female, Humans, Indoles adverse effects, Indoles pharmacology, Indoles therapeutic use, Pain, Postoperative physiopathology, Phenylpropionates adverse effects, Phenylpropionates therapeutic use, Research Design, Time Factors, Analgesics pharmacology, Drug Evaluation methods, Pain, Postoperative drug therapy, Phenylpropionates pharmacology
Abstract

Parametric tests for bioassay data are commonly applied to scores of pain intensity and relief for the assessment of potency ratios of analgesic drugs. It has been demonstrated, however, that scores derived from semiquantitative scales often deviate from normal distribution. In addition, when scores decrease as a consequence of analgesic treatment, the variances may be nonhomogenous. Both parametric and nonparametric procedures have been employed in this study for the evaluation of results of a double-blind multicenter trial of the analgesic effect of indoprofen and ASA (both drugs at three dose levels) and placebo in episiotomy pain. There was a good agreement between potency ratios obtained with the two assays. Peak PID appeared a less efficient means of estimating potency ratio than other measurements such as SPID and TOTPAR. The nonparametric test for quantitative bioassay appears to be a valid statistical procedure for evaluating results of clinical trials, and it does not imply any assumptions as to the type of distribution of the data.

Published
1977
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17. Intravenous catheter-associated Malassezia furfur fungemia.

Author

Garcia CR, Johnston BL, Corvi G, Walker LJ, and George WL

Subjects
Humans, Male, Middle Aged, Parenteral Nutrition, Total, Catheters, Indwelling adverse effects, Fat Emulsions, Intravenous, Malassezia isolation & purification, Tinea Versicolor
Abstract

Malassezia furfur, a lipophilic yeast that is the etiologic agent of tinea versicolor, has not been considered as a cause of serious illness in adults in the past. Two adults are described in whom Malassezia furfur fungemia developed while receiving total parenteral nutrition supplemented with lipids. The organism was identified in blood cultures from both patients only after isolation media were supplemented with a source of fatty acids. Because M. furfur will grow only in media supplemented with fatty acids, clinicians should alert the laboratory whenever a lipophilic organism is suspected to be present in blood cultures.

Published
1987
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19. Effect of food on absorption of indoprofen administered orally to man in two dosage forms.

Author

Tamassia V, Corvi G, Moro E, Tosolini GP, and Fuccella LM

Subjects
Administration, Oral, Adult, Anti-Inflammatory Agents, Non-Steroidal administration & dosage, Biological Availability, Capsules, Humans, Indoles administration & dosage, Indoles metabolism, Male, Phenylpropionates administration & dosage, Tablets, Time Factors, Anti-Inflammatory Agents, Non-Steroidal metabolism, Food, Intestinal Absorption, Phenylpropionates metabolism
Abstract

The influence of food on the bioavailability of two oral dosage forms (100-mg capsules and 200-mg tablets) of indoprofen, a new propionic acid derivative with marked anti-inflammatory and analgesic properties, has been investigated. Plasma levels and urinary excretion of indoprofen were determined both in the fasting state and after a standard meal in healthy volunteers after administration of two 100-mg capsules (4 subjects) and of one 200-mg tablet (6 subjects). Indoprofen in biological fluids was determined by gas-liquid chromatography. The extent of absorption from tablets was not affected by food as indicated from the values of the total area under plasma level curves and urinary excretion of the drug. The rate of absorption was faster after meal than in the fasting state. The opposite was found for capsules, which showed a slightly delayed absorption after food. The results suggest that food may differently influence the absorption pattern of different pharmaceutical forms of the same drug.

Published
1977

20. [Diagnostic considerations on masked depression in medical practice: personal studies on treatment with bromazepam].

Author

Ferrari A and Corvi G

Subjects
Adolescent, Adult, Depression drug therapy, Depression etiology, Eczema complications, Feeding and Eating Disorders complications, Female, Humans, Male, Middle Aged, Physician-Patient Relations, Psychophysiologic Disorders diagnosis, Psychophysiologic Disorders drug therapy, Sleep Wake Disorders complications, Anti-Anxiety Agents therapeutic use, Bromazepam therapeutic use, Depression diagnosis
Published
1979

21. Pharmacokinetic studies of indoprofen in healthy volunteers and in patients.

Author

Caruso I, Corvi G, Fuccella LM, Moro E, Sacchetti G, Tamassia V, and Tosolini GP

Subjects
Administration, Oral, Adult, Aged, Anti-Inflammatory Agents, Non-Steroidal administration & dosage, Arthritis, Rheumatoid metabolism, Female, Half-Life, Humans, Indoles administration & dosage, Indoles metabolism, Injections, Intramuscular, Kinetics, Male, Middle Aged, Phenylpropionates administration & dosage, Time Factors, Anti-Inflammatory Agents, Non-Steroidal metabolism, Phenylpropionates metabolism
Abstract

The pharmacokinetics of indoprofen in healthy subjects after single oral and i.v. administrations is reviewed. During repeated administration of indoprofen to 6 normal subjects (200-mg tablet every 8 hours for 6 days) no variations in the disposition of the drug were found in comparison with single dose administration. In 6 inpatients, with rheumatoid arthritis, the pharmacokinetics of indoprofen was studied after single oral (tablet) and i.m. administration. As for oral doses, no difference in main kinetic parameters was detected between the patients and normal subjects except for a higher volume of distribution in the former population. The bioavailability of the drug given by i.m. injection was not significantly different from that observed after oral administration.

Published
1977

22. Double-blind study of the analgesic effect of indoprofen (K 4277).

Author

Fuccella LM, Conti F, Corvi G, Mandelli V, Randelli M, and Stefanelli G

Subjects
Adult, Aged, Analgesics administration & dosage, Analgesics adverse effects, Clinical Trials as Topic, Female, Humans, Indoles administration & dosage, Indoles adverse effects, Indoles therapeutic use, Male, Middle Aged, Neoplasm Metastasis, Neuralgia, Palliative Care, Phenylpropionates administration & dosage, Phenylpropionates adverse effects, Placebos, Time Factors, Analgesics therapeutic use, Pain drug therapy, Phenylpropionates therapeutic use
Abstract

In a double-blind study, indoprofen was superior to placebo in decreasing pain in patients with primary and metastatic cancer and with neuralgia. A single oral dose of 200 mg was more active than a 100-mg dose. The preferences of patients proved to be a more sensitive parameter in this study than scores of pain intensity, pain relief, and other related measurements (SPID, TOTPAR, and Peak PID).

Published
1975
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32. [A case of epithelioid epulis].

Author

CORVI G and PANNELLA A

Subjects
Animals, Humans, Giant Cell Tumors, Gingiva, Gingival Diseases, Gingival Neoplasms, Medical Records, Neoplasms
Published
1959

33. [Methacycline in dentistry].

Author

Ossido G, Sfondrini G, Zampetti G, and Corvi G

Subjects
Adolescent, Adult, Aged, Humans, Methacycline therapeutic use, Middle Aged, Jaw Diseases drug therapy, Mouth Diseases drug therapy, Tetracycline therapeutic use, Tooth Diseases drug therapy
Published
1966

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