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1. The sensory shark: high-quality phenotypic, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates

Author

Mayeur, Helene, primary, Leyhr, Jake, additional, Mulley, John, additional, Nicolas, Leurs, additional, Michel, Leo, additional, Sharma, Kanika, additional, Lagadec, Ronan, additional, Aury, Jean-Marc, additional, Osborne, Owen Gregory, additional, Mulhair, Peter, additional, Poulain, Julie, additional, Mangenot, Sophie, additional, Mead, Daniel, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Dolucan, Jale, additional, Dudchenko, Olga, additional, Omer, Arina, additional, Weisz, David, additional, Lieberman-Aiden, Erez, additional, McCarthy, Shane, additional, Sims, Ying, additional, Torrance, James, additional, Tracey, Alan, additional, Howe, Kerstin, additional, Baril, Tobias, additional, Hayward, Alex, additional, Martinand-Mari, Camille, additional, Sanchez, Sophie, additional, Haitina, Tatjana, additional, Martin, Kyle John, additional, MAZAN, Sylvie, additional, Korsching, Sigrun I, additional, and Debiais-Thibaud, Melanie, additional

Published
2024
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2. The Genome of the African Trypanosome Trypanosoma brucei

Author

Berriman, Matthew, Ghedin, Elodie, Hertz-Fowler, Christiane, Blandin, Gaëlle, Renauld, Hubert, Bartholomeu, Daniella C., Lennard, Nicola J., Caler, Elisabet, Hamlin, Nancy E., Haas, Brian, Böhme, Ulrike, Hannick, Linda, Aslett, Martin A., Shallom, Joshua, Marcello, Lucio, Hou, Lihua, Wickstead, Bill, Arrowsmith, Claire, Atkin, Rebecca J., Barron, Andrew J., Bringaud, Frederic, Brooks, Karen, Carrington, Mark, Cherevach, Inna, Chillingworth, Tracey-Jane, Churcher, Carol, Clark, Louise N., Corton, Craig H., Cronin, Ann, Davies, Rob M., Doggett, Jonathon, Djikeng, Appolinaire, Feldblyum, Tamara, Field, Mark C., Fraser, Audrey, Goodhead, Ian, Hance, Zahra, Harper, David, Harris, Barbara R., Hauser, Heidi, Hostetler, Jessica, Ivens, Al, Jagels, Kay, Johnson, David, Johnson, Justin, Jones, Kristine, Kerhornou, Arnaud X., Koo, Hean, Larke, Natasha, Landfear, Scott, Larkin, Christopher, Leech, Vanessa, Line, Alexandra, Lord, Angela, MacLeod, Annette, Mooney, Paul J., Moule, Sharon, Morgan, Gareth W., Mungall, Karen, Norbertczak, Halina, Ormond, Doug, Pai, Grace, Peacock, Chris S., Peterson, Jeremy, Quail, Michael A., Rabbinowitsch, Ester, Rajandream, Marie-Adele, Reitter, Chris, Salzberg, Steven L., Sanders, Mandy, Schobel, Seth, Sharp, Sarah, Simmonds, Mark, Simpson, Anjana J., Tallon, Luke, Tait, Andrew, Tivey, Adrian R., Van Aken, Susan, Walker, Danielle, Wanless, David, Wang, Shiliang, White, Brian, White, Owen, Whitehead, Sally, Woodward, John, Wortman, Jennifer, Adams, Mark D., Embley, T. Martin, Gull, Keith, Ullu, Elisabetta, Barry, J. David, Fairlamb, Alan H., Opperdoes, Fred, Barrell, Barclay G., Donelson, John E., Hall, Neil, Fraser, Claire M., Melville, Sara E., and El-Sayed, Najib M.

Published
2005

3. The Genome of the Heartwater Agent Ehrlichia ruminantium Contains Multiple Tandem Repeats of Actively Variable Copy Number

Author

Collins, Nicola E., Liebenberg, Junita, de Villiers, Etienne P., Brayton, Kelly A., Louw, Elmarié, Pretorius, Alri, Faber, F. Erika, van Heerden, Henriette, Josemans, Antoinette, van Kleef, Mirinda, Steyn, Helena C., van Strijp, M. Fransie, Zweygarth, Erich, Jongejan, Frans, Maillard, Jean Charles, Berthier, David, Botha, Marli, Joubert, Fourie, Corton, Craig H., Thomson, Nicholas R., Allsopp, Maria T., Allsopp, Basil A., and Beaty, Barry J.

Published
2005

4. Complete Genomes of Two Clinical Staphylococcus aureus Strains: Evidence for the Rapid Evolution of Virulence and Drug Resistance

Author

Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Enright, Mark C., Foster, Tim J., Moore, Catrin E., Hurst, Laurence, Atkin, Rebecca, Barron, Andrew, Bason, Nathalie, Bentley, Stephen D., Chillingworth, Carol, Chillingworth, Tracey, Churcher, Carol, Clark, Louise, Corton, Craig, Cronin, Ann, Doggett, Jon, Dowd, Linda, Feltwell, Theresa, Hance, Zahra, Harris, Barbara, Hauser, Heidi, Holroyd, Simon, Jagels, Kay, James, Keith D., Lennard, Nicola, Line, Alexandra, Mayes, Rebecca, Moule, Sharon, Mungall, Karen, Ormond, Douglas, Quail, Michael A., Rabbinowitsch, Ester, Rutherford, Kim, Sanders, Mandy, Sharp, Sarah, Simmonds, Mark, Stevens, Kim, Whitehead, Sally, Barrell, Bart G., Spratt, Brian G., Parkhill, Julian, and Mekalanos, John J.

Published
2004

5. Extensive DNA Inversions in the B. fragilis Genome Control Variable Gene Expression

Author

Cerdeño-Tárraga, Ana M., Patrick, Sheila, Crossman, Lisa C., Blakely, Garry, Abratt, Val, Lennard, Nicola, Poxton, Ian, Duerden, Brian, Harris, Barbara, Quail, Mike A., Barron, Andrew, Clark, Louise, Corton, Craig, Doggett, Jonathan, Larke, Natasha, Line, Alexandra, Lord, Angela, Norbertczak, Halina, Ormond, Doug, Price, Claire, Rabbinowitsch, Ester, Woodward, John, Barrell, Bart, and Parkhill, Julian

Published
2005

8. Evolutionary dynamics of Clostridium difficile over short and long time scales

Author

He, Miao, Sebaihia, Mohammed, Lawley, Trevor D., Stabler, Richard A., Dawson, Lisa F., Martin, Melissa J., Holt, Kathryn E., Seth-Smith, Helena M.B., Quail, Michael A., Rance, Richard, Brooks, Karen, Churcher, Carol, Harris, David, Bentley, Stephen D., Burrows, Christine, Clark, Louise, Corton, Craig, Murray, Vicky, Rose, Graham, Thurston, Scott, van Tonder, Andries, Walker, Danielle, Wren, Brendan W., Dougan, Gordon, Parkhill, Julian, and Rappuoli, Rino

Published
2010

9. The genome sequence of the European golden eagle, Aquila chrysaetos chrysaetos Linnaeus 1758

Author

Mead, Dan, Ogden, Rob, Meredith, Anna, Peniche, Gabriela, Smith, Michelle, Corton, Craig, Oliver, Karen, Skelton, Jason, Betteridge, Emma, Doulcan, Jale, Holmes, Nadine, Wright, Victoria, Loose, Matt, Quail, Michael A, McCarthy, Shane A, Howe, Kerstin, Chow, William, Torrance, James, Collins, Joanna, Challis, Richard, Durbin, Richard, Blaxter, Mark, Mead, Dan [0000-0001-7717-4330], Ogden, Rob [0000-0002-2831-0428], Doulcan, Jale [0000-0002-3551-1770], Wright, Victoria [0000-0002-9288-4338], Loose, Matt [0000-0002-5264-0929], McCarthy, Shane A [0000-0002-2715-4187], Howe, Kerstin [0000-0003-2237-513X], Torrance, James [0000-0002-6117-8190], Challis, Richard [0000-0002-3502-1122], Durbin, Richard [0000-0002-9130-1006], and Apollo - University of Cambridge Repository

Subjects
Aquila chrysaetos, genome sequence, European golden eagle, chromosomal
Abstract

We present a genome assembly from an individual female Aquila chrysaetos chrysaetos (the European golden eagle; Chordata; Aves; Accipitridae). The genome sequence is 1.23 gigabases in span. The majority of the assembly is scaffolded into 28 chromosomal pseudomolecules, including the W and Z sex chromosomes.

Published
2021
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10. Complete vertebrate mitogenomes reveal widespread repeats and gene duplications

Author

Formenti, Giulio, Rhie, Arang, Balacco, Jennifer, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Brown, Samara, Capodiferro, Marco Rosario, Al-Ajli, Farooq O., Ambrosini, Roberto, Houde, Peter, Koren, Sergey, Oliver, Karen, Smith, Michelle, Skelton, Jason, Betteridge, Emma, Dolucan, Jale, Corton, Craig, Bista, Iliana, Torrance, James, Tracey, Alan, Wood, Jonathan, Uliano-Silva, Marcela, Howe, Kerstin, McCarthy, Shane, Winkler, Sylke, Kwak, Woori, Korlach, Jonas, Fungtammasan, Arkarachai, Fordham, Daniel, Costa, Vania, Mayes, Simon, Chiara, Matteo, Horner, David S., Myers, Eugene, Durbin, Richard, Achilli, Alessandro, Braun, Edward L., Phillippy, Adam M., Jarvis, Erich D., Kirschel, Alexander N. G., Digby, Andrew, Veale, Andrew, Bronikowski, Anne, Murphy, Bob, Robertson, Bruce, Baker, Clare, Mazzoni, Camila, Balakrishnan, Christopher, Lee, Chul, Mead, Daniel, Teeling, Emma, Aiden, Erez Lieberman, Todd, Erica, Eichler, Evan, Naylor, Gavin J. P., Zhang, Guojie, Smith, Jeramiah, Wolf, Jochen, Touchon, Justin, Delmore, Kira, Jakobsen, Kjetill, Komoroske, Lisa, Wilkinson, Mark, Genner, Martin, Pšenička, Martin, Fuxjager, Matthew, Stratton, Mike, Liedvogel, Miriam, Gemmell, Neil, Minias, Piotr, Dunn, Peter O., Sudmant, Peter, Morin, Phil, Ayub, Qasim, Kraus, Robert, Vernes, Sonja, Smith, Steve, Lama, Tanya, Edwards, Taylor, Smith, Tim, Gilbert, Tom, Marques-Bonet, Tomas, Einfeldt, Tony, Venkatesh, Byrappa, Johnson, Warren, Warren, Wes, Bukhman, Yury, Formenti, Giulio [0000-0002-7554-5991], and Apollo - University of Cambridge Repository

Subjects
Vertebrate, Research, Assembly, Sequencing, Duplications, Long reads, Repeats, Mitochondrial DNA
Abstract

Background: Modern sequencing technologies should make the assembly of the relatively small mitochondrial genomes an easy undertaking. However, few tools exist that address mitochondrial assembly directly. Results: As part of the Vertebrate Genomes Project (VGP) we develop mitoVGP, a fully automated pipeline for similarity-based identification of mitochondrial reads and de novo assembly of mitochondrial genomes that incorporates both long (> 10 kbp, PacBio or Nanopore) and short (100–300 bp, Illumina) reads. Our pipeline leads to successful complete mitogenome assemblies of 100 vertebrate species of the VGP. We observe that tissue type and library size selection have considerable impact on mitogenome sequencing and assembly. Comparing our assemblies to purportedly complete reference mitogenomes based on short-read sequencing, we identify errors, missing sequences, and incomplete genes in those references, particularly in repetitive regions. Our assemblies also identify novel gene region duplications. The presence of repeats and duplications in over half of the species herein assembled indicates that their occurrence is a principle of mitochondrial structure rather than an exception, shedding new light on mitochondrial genome evolution and organization. Conclusions: Our results indicate that even in the “simple” case of vertebrate mitogenomes the completeness of many currently available reference sequences can be further improved, and caution should be exercised before claiming the complete assembly of a mitogenome, particularly from short reads alone.

Published
2021

11. Description and nomenclature of Neisseria meningitidis capsule locus

Author

Harrison, Odile B., Claus, Heike, Jiang, Ying, Bennett, Julia S., Bratcher, Holly B., Jolley, Keith A., Corton, Craig, Care, Rory, Poolman, Jan T., Zollinger, Wendell D., Frasch, Carl E., Stephens, David S., Feavers, Ian, Frosch, Matthias, Parkhill, Julian, Vogel, Ulrich, Quail, Michael A., Bentley, Stephen D., and Maiden, Martin C.J.

Subjects
Neisseria meningitidis -- Identification and classification -- Health aspects -- Genetic aspects -- Research, Nuclear magnetic resonance spectroscopy -- Usage -- Health aspects, Polymerase chain reaction -- Usage, Health
Abstract

Thirteen Neisseria meningitidis serogroups have been described on the basis of serologic differences of the capsule; of these 13 serogroups, 6 (A, B, C, W, X, Y) cause invasive meningococcal [...]

Published
2013
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12. The complete genome sequence of Eimeria tenella (Tyzzer 1929), a common gut parasite of chickens

Author

Aunin, Eerik, primary, Böhme, Ulrike, additional, Blake, Damer, additional, Dove, Alexander, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Betteridge, Emma, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Wood, Jonathan, additional, Tracey, Alan, additional, Torrance, James, additional, Sims, Ying, additional, Howe, Kerstin, additional, Challis, Richard, additional, Berriman, Matthew, additional, and Reid, Adam, additional

Published
2021
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13. Using de novo assembly to identify structural variation of eight complex immune system gene regions

Author

Zhang, Jia-Yuan, primary, Roberts, Hannah, additional, Flores, David S. C., additional, Cutler, Antony J., additional, Brown, Andrew C., additional, Whalley, Justin P., additional, Mielczarek, Olga, additional, Buck, David, additional, Lockstone, Helen, additional, Xella, Barbara, additional, Oliver, Karen, additional, Corton, Craig, additional, Betteridge, Emma, additional, Bashford-Rogers, Rachael, additional, Knight, Julian C., additional, Todd, John A., additional, and Band, Gavin, additional

Published
2021
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14. The genome sequence of the European turtle dove, Streptopelia turtur Linnaeus 1758

Author

Dunn, Jenny C., primary, Hamer, Keith C., additional, Morris, Antony J., additional, Grice, Philip V., additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Dolucan, Jale, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Uliano-Silva, Marcela, additional, Howe, Kerstin, additional, Torrance, James, additional, Chow, William, additional, Pelan, Sarah, additional, Sims, Ying, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, Mead, Daniel, additional, and Blaxter, Mark, additional

Published
2021
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15. The genome sequence of the European robin, Erithacus rubecula Linnaeus 1758

Author

Dunn, Jenny C., primary, Liedvogel, Miriam, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Dolucan, Jale, additional, Quail, Michael A., additional, Uliano-Silva, Marcela, additional, McCarthy, Shane A., additional, Howe, Kerstin, additional, Torrance, James, additional, Wood, Jonathan, additional, Pelan, Sarah, additional, Sims, Ying, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, Mead, Daniel, additional, and Blaxter, Mark, additional

Published
2021
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16. The genome sequence of the European water vole, Arvicola amphibius Linnaeus 1758

Author

Carpenter, Angus I, Smith, Michelle, Corton, Craig, Oliver, Karen, Skelton, Jason, Betteridge, Emma, Doulcan, Jale, Quail, Michael A, McCarthy, Shane A, Uliano Da Silva, Marcela, Howe, Kerstin, Torrance, James, Wood, Jonathan, Pelan, Sarah, Sims, Ying, Tricomi, Francesca Floriana, Challis, Richard, Threlfall, Jonathan, Mead, Daniel, Blaxter, Mark, Carpenter, Angus I [0000-0002-0262-9895], Doulcan, Jale [0000-0002-3551-1770], Howe, Kerstin [0000-0003-2237-513X], Torrance, James [0000-0002-6117-8190], Wood, Jonathan [0000-0002-7545-2162], Tricomi, Francesca Floriana [0000-0002-6170-5499], Challis, Richard [0000-0002-3502-1122], Threlfall, Jonathan [0000-0001-8599-4320], Mead, Daniel [0000-0001-7717-4330], Blaxter, Mark [0000-0003-2861-949X], and Apollo - University of Cambridge Repository

Subjects
genome sequence, chromosomal, European water vole, Arvicola amphibius
Abstract

We present a genome assembly from an individual male Arvicola amphibius (the European water vole; Chordata; Mammalia; Rodentia; Cricetidae). The genome sequence is 2.30 gigabases in span. The majority of the assembly is scaffolded into 18 chromosomal pseudomolecules, including the X sex chromosome. Gene annotation of this assembly on Ensembl has identified 21,394 protein coding genes.

Published
2021

17. The genome sequence of the brown trout, Salmo trutta Linnaeus 1758

Author

Hansen, Tom, Fjelldal, Per Gunnar, Lien, Sigbjørn, Smith, Michelle, Corton, Craig, Oliver, Karen, Skelton, Jason, Betteridge, Emma, Doulcan, Jale, Fedrigo, Olivier, Mountcastle, Jacquelyn, Jarvis, Erich, McCarthy, Shane A, Chow, William, Howe, Kerstin, Torrance, James, Wood, Jonathan, Sims, Ying, Haggerty, Leanne, Challis, Richard, Threlfall, Jonathan, Mead, Daniel, Durbin, Richard, Blaxter, Mark, Hansen, Tom [0000-0002-4784-5014], Doulcan, Jale [0000-0002-3551-1770], Fedrigo, Olivier [0000-0002-6450-7551], Mountcastle, Jacquelyn [0000-0003-1078-4905], Howe, Kerstin [0000-0003-2237-513X], Torrance, James [0000-0002-6117-8190], Wood, Jonathan [0000-0002-7545-2162], Challis, Richard [0000-0002-3502-1122], Threlfall, Jonathan [0000-0001-8599-4320], Mead, Daniel [0000-0001-7717-4330], Durbin, Richard [0000-0002-9130-1006], Blaxter, Mark [0000-0003-2861-949X], and Apollo - University of Cambridge Repository

Subjects
brown trout, animal diseases, genome sequence, Salmo trutta, chromosomal
Abstract

We present a genome assembly from an individual female Salmo trutta (the brown trout; Chordata; Actinopteri; Salmoniformes; Salmonidae). The genome sequence is 2.37 gigabases in span. The majority of the assembly is scaffolded into 40 chromosomal pseudomolecules. Gene annotation of this assembly on Ensembl has identified 43,935 protein coding genes.

Published
2021

18. The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769

Author

Howe, Kerstin, Dwinell, Melinda, Shimoyama, Mary, Corton, Craig, Betteridge, Emma, Dove, Alexander, Quail, Michael A, Smith, Michelle, Saba, Laura, Williams, Robert W, Chen, Hao, Kwitek, Anne E, McCarthy, Shane A, Uliano-Silva, Marcela, Chow, William, Tracey, Alan, Torrance, James, Sims, Ying, Challis, Richard, Threlfall, Jonathan, Blaxter, Mark, Howe, Kerstin [0000-0003-2237-513X], Saba, Laura [0000-0001-9649-1294], Williams, Robert W [0000-0001-8924-4447], Kwitek, Anne E [0000-0003-1024-4116], Tracey, Alan [0000-0002-4805-9058], Torrance, James [0000-0002-6117-8190], Challis, Richard [0000-0002-3502-1122], Threlfall, Jonathan [0000-0001-8599-4320], Blaxter, Mark [0000-0003-2861-949X], and Apollo - University of Cambridge Repository

Subjects
genome sequence, chromosomal, Rattus norvegicus, reference genome, Norway rat
Abstract

We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules, with both X and Y sex chromosomes assembled. This genome assembly, mRatBN7.2, represents the new reference genome for R. norvegicus and has been adopted by the Genome Reference Consortium.

Published
2021

19. Additional file 8 of Complete vertebrate mitogenomes reveal widespread repeats and gene duplications

Author

Formenti, Giulio, Arang Rhie, Balacco, Jennifer, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Brown, Samara, Capodiferro, Marco Rosario, Al-Ajli, Farooq O., Ambrosini, Roberto, Houde, Peter, Koren, Sergey, Oliver, Karen, Smith, Michelle, Skelton, Jason, Betteridge, Emma, Dolucan, Jale, Corton, Craig, Bista, Iliana, Torrance, James, Tracey, Alan, Wood, Jonathan, Uliano-Silva, Marcela, Howe, Kerstin, McCarthy, Shane, Winkler, Sylke, Woori Kwak, Korlach, Jonas, Arkarachai Fungtammasan, Fordham, Daniel, Costa, Vania, Mayes, Simon, Chiara, Matteo, Horner, David S., Myers, Eugene, Durbin, Richard, Achilli, Alessandro, Braun, Edward L., Phillippy, Adam M., and Jarvis, Erich D.

Abstract

Additional file 8: Supplementary Note 1. Relationship between mtDNA sequencing, coverage and genome size.

Published
2021
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20. Additional file 12 of Complete vertebrate mitogenomes reveal widespread repeats and gene duplications

Author

Formenti, Giulio, Arang Rhie, Balacco, Jennifer, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Brown, Samara, Capodiferro, Marco Rosario, Al-Ajli, Farooq O., Ambrosini, Roberto, Houde, Peter, Koren, Sergey, Oliver, Karen, Smith, Michelle, Skelton, Jason, Betteridge, Emma, Dolucan, Jale, Corton, Craig, Bista, Iliana, Torrance, James, Tracey, Alan, Wood, Jonathan, Uliano-Silva, Marcela, Howe, Kerstin, McCarthy, Shane, Winkler, Sylke, Woori Kwak, Korlach, Jonas, Arkarachai Fungtammasan, Fordham, Daniel, Costa, Vania, Mayes, Simon, Chiara, Matteo, Horner, David S., Myers, Eugene, Durbin, Richard, Achilli, Alessandro, Braun, Edward L., Phillippy, Adam M., and Jarvis, Erich D.

Abstract

Additional file 12. Review history.

Published
2021
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21. Twenty-eight divergent polysaccharide loci specifying within- and amongst-strain capsule diversity in three strains of Bacteroides fragilis

Author

Patrick, Sheila, Blakely, Garry W., Houston, Simon, Moore, Jane, Abratt, Valerie R., Bertalan, Marcelo, Cerdeno-Tarraga, Ana M., Quail, Michael A., Cotton, Nicola, Corton, Craig, Bignell, Alexandra, Barron, Andrew, Clark, Louise, Bentley, Stephen D., and Julian Parkhill

Subjects
Anaerobic bacteria -- Genetic aspects, Anaerobic bacteria -- Research, Nucleotide sequence -- Research, Polysaccharides -- Research, Polysaccharides -- Physiological aspects, Biological sciences
Abstract

Comparison of the complete genome sequence of Bacteroides fragilis 638R, originally isolated in the USA, was made with two previously sequenced strains isolated in the UK (NCTC 9343) and Japan (YCH46). The presence of 10 loci containing genes associated with polysaccharide (PS) biosynthesis, each including a putative Wzx flippase and Wzy polymerase, was confirmed in all three strains, despite a lack of cross-reactivity between NCTC 9343 and 638R surface PS-specific antibodies by immunolabelling and microscopy. Genomic comparisons revealed an exceptional level of PS biosynthesis locus diversity. Of the 10 divergent PS-associated loci apparent in each strain, none is similar between NCTC 9343 and 638R. YCH46 shares one locus with NCTC 9343, confirmed by mAb labelling, and a second different locus with 638R, making a total of 28 divergent PS biosynthesis loci amongst the three strains. The lack of expression of the phase-variable large capsule (LC) in strain 638R, observed in NCTC 9343, is likely to be due to a point mutation that generates a stop codon within a putative initiating glycosyltransferase, necessary for the expression of the LC in NCTC 9343. Other major sequence differences were observed to arise from different numbers and variety of inserted extra-chromosomal elements, in particular prophages. Extensive horizontal gene transfer has occurred within these strains, despite the presence of a significant number of divergent DNA restriction and modification systems that act to prevent acquisition of foreign DNA. The level of amongst-strain diversity in PS biosynthesis loci is unprecedented. DOI 10.1099/mic.0.042978-0

Published
2010

22. Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW)

Author

Holden, Matthew T.G., Lindsay, Jodi A., Corton, Craig, Quail, Michael A., Cockfield, Joshua D., Pathak, Smriti, Batra, Rahul, Parkhill, Julian, Bentley, Stephen D., and Edgeworth, Jonathan D.

Subjects
Staphylococcus aureus -- Genetic aspects, Staphylococcus aureus -- Research, Gene mutations -- Research, Drug resistance in microorganisms -- Genetic aspects, Drug resistance in microorganisms -- Research, Biological sciences
Abstract

The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes. doi: 10.1128/JB.01255-09

Published
2010

23. The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli

Author

Petty, Nicola K., Bulgin, Richard, Crepin, Valerie F., Cerdeno-Tarraga, Ana M., Schroeder, Gunnar N., Quail, Michael A., Lennard, Nicola, Corton, Craig, Barron, Andrew, Clark, Louise, Toribio, Ana L., Parkhill, Julian, Dougan, Gordon, Frankel, Gad, and Thomson, Nicholas R.

Subjects
Convergence (Biology) -- Research, Escherichia coli -- Genetic aspects, Biological sciences
Abstract

Citrobacter rodentium (formally Citrobacterfreundii biotype 4280) is a highly infectious pathogen that causes colitis and transmissible colonic hyperplasia in mice. In common with enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC, respectively), C. rodentium exploits a type III secretion system (T3SS) to induce attaching and effacing (A/E) lesions that are essential for virulence. Here, we report the fully annotated genome sequence of the 5.3-Mb chromosome and four plasmids harbored by C. rodentium strain ICC168. The genome sequence revealed key information about the phylogeny of C. rodentium and identified 1,585 C. rodentium-specific (without orthologues in EPEC or EHEC) coding sequences, 10 prophage-like regions, and 17 genomic islands, including the locus for enterocyte effacement (LEE) region, which encodes a T3SS and effector proteins. Among the 29 T3SS effectors found in C. rodentium are all 22 of the core effectors of EPEC strain E2348/69. In addition, we identified a novel C. rodentium effector, named EspS. C. rodentium harbors two type VI secretion systems (T6SS) (CTS1 and CTS2), while EHEC contains only one T6SS (EHS). Our analysis suggests that C. rodentium and EPEC/EHEC have converged on a common host infection strategy through access to a common pool of mobile DNA and that C. rodentium has lost gene functions associated with a previous pathogenic niche. doi: 10.1128/JB.01144-09

Published
2010

24. The genome sequence of the ringlet, Aphantopus hyperantus Linnaeus 1758

Author

Mead, Dan, primary, Saccheri, Ilik, additional, Yung, Carl J., additional, Lohse, Konrad, additional, Lohse, Carla, additional, Ashmole, Philip, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Quail, Michael A., additional, Dolucan, Jale, additional, McCarthy, Shane A., additional, Howe, Kerstin, additional, Wood, Jonathan, additional, Torrance, James, additional, Tracey, Alan, additional, Whiteford, Sam, additional, Challis, Richard, additional, Durbin, Richard, additional, and Blaxter, Mark, additional

Published
2021
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25. The genome sequence of the European water vole, Arvicola amphibius Linnaeus 1758

Author

Carpenter, Angus I., primary, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Doulcan, Jale, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Uliano Da Silva, Marcela, additional, Howe, Kerstin, additional, Torrance, James, additional, Wood, Jonathan, additional, Pelan, Sarah, additional, Sims, Ying, additional, Tricomi, Francesca Floriana, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, Mead, Daniel, additional, and Blaxter, Mark, additional

Published
2021
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26. Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Author

Meng, Bo, primary, Kemp, Steven A., additional, Papa, Guido, additional, Datir, Rawlings, additional, Ferreira, Isabella A.T.M., additional, Marelli, Sara, additional, Harvey, William T., additional, Lytras, Spyros, additional, Mohamed, Ahmed, additional, Gallo, Giulia, additional, Thakur, Nazia, additional, Collier, Dami A., additional, Mlcochova, Petra, additional, Duncan, Lidia M., additional, Carabelli, Alessandro M., additional, Kenyon, Julia C., additional, Lever, Andrew M., additional, De Marco, Anna, additional, Saliba, Christian, additional, Culap, Katja, additional, Cameroni, Elisabetta, additional, Matheson, Nicholas J., additional, Piccoli, Luca, additional, Corti, Davide, additional, James, Leo C., additional, Robertson, David L., additional, Bailey, Dalan, additional, Gupta, Ravindra K., additional, Robson, Samuel C., additional, Loman, Nicholas J., additional, Connor, Thomas R., additional, Golubchik, Tanya, additional, Martinez Nunez, Rocio T., additional, Ludden, Catherine, additional, Corden, Sally, additional, Johnston, Ian, additional, Bonsall, David, additional, Smith, Colin P., additional, Awan, Ali R., additional, Bucca, Giselda, additional, Torok, M. Estee, additional, Saeed, Kordo, additional, Prieto, Jacqui A., additional, Jackson, David K., additional, Hamilton, William L., additional, Snell, Luke B., additional, Moore, Catherine, additional, Harrison, Ewan M., additional, Goncalves, Sonia, additional, Fairley, Derek J., additional, Loose, Matthew W., additional, Watkins, Joanne, additional, Livett, Rich, additional, Moses, Samuel, additional, Amato, Roberto, additional, Nicholls, Sam, additional, Bull, Matthew, additional, Smith, Darren L., additional, Barrett, Jeff, additional, Aanensen, David M., additional, Curran, Martin D., additional, Parmar, Surendra, additional, Aggarwal, Dinesh, additional, Shepherd, James G., additional, Parker, Matthew D., additional, Glaysher, Sharon, additional, Bashton, Matthew, additional, Underwood, Anthony P., additional, Pacchiarini, Nicole, additional, Loveson, Katie F., additional, Templeton, Kate E., additional, Langford, Cordelia F., additional, Sillitoe, John, additional, de Silva, Thushan I., additional, Wang, Dennis, additional, Kwiatkowski, Dominic, additional, Rambaut, Andrew, additional, O’Grady, Justin, additional, Cottrell, Simon, additional, Holden, Matthew T.G., additional, Thomson, Emma C., additional, Osman, Husam, additional, Andersson, Monique, additional, Chauhan, Anoop J., additional, Hassan-Ibrahim, Mohammed O., additional, Lawniczak, Mara, additional, Alderton, Alex, additional, Chand, Meera, additional, Constantinidou, Chrystala, additional, Unnikrishnan, Meera, additional, Darby, Alistair C., additional, Hiscox, Julian A., additional, Paterson, Steve, additional, Martincorena, Inigo, additional, Volz, Erik M., additional, Page, Andrew J., additional, Pybus, Oliver G., additional, Bassett, Andrew R., additional, Ariani, Cristina V., additional, Chapman, Michael H. Spencer, additional, Li, Kathy K., additional, Shah, Rajiv N., additional, Jesudason, Natasha G., additional, Taha, Yusri, additional, McHugh, Martin P., additional, Dewar, Rebecca, additional, Jahun, Aminu S., additional, McMurray, Claire, additional, Pandey, Sarojini, additional, McKenna, James P., additional, Nelson, Andrew, additional, Young, Gregory R., additional, McCann, Clare M., additional, Elliott, Scott, additional, Lowe, Hannah, additional, Temperton, Ben, additional, Roy, Sunando, additional, Price, Anna, additional, Rey, Sara, additional, Wyles, Matthew, additional, Rooke, Stefan, additional, Shaaban, Sharif, additional, de Cesare, Mariateresa, additional, Letchford, Laura, additional, Silveira, Siona, additional, Pelosi, Emanuela, additional, Wilson-Davies, Eleri, additional, Hosmillo, Myra, additional, O’Toole, Áine, additional, Hesketh, Andrew R., additional, Stark, Richard, additional, du Plessis, Louis, additional, Ruis, Chris, additional, Adams, Helen, additional, Bourgeois, Yann, additional, Michell, Stephen L., additional, Grammatopoulos, Dimitris, additional, Edgeworth, Jonathan, additional, Breuer, Judith, additional, Todd, John A., additional, Fraser, Christophe, additional, Buck, David, additional, John, Michaela, additional, Kay, Gemma L., additional, Palmer, Steve, additional, Peacock, Sharon J., additional, Heyburn, David, additional, Weldon, Danni, additional, Robinson, Esther, additional, McNally, Alan, additional, Muir, Peter, additional, Vipond, Ian B., additional, Boyes, John, additional, Sivaprakasam, Venkat, additional, Salluja, Tranprit, additional, Dervisevic, Samir, additional, Meader, Emma J., additional, Park, Naomi R., additional, Oliver, Karen, additional, Jeffries, Aaron R., additional, Ott, Sascha, additional, da Silva Filipe, Ana, additional, Simpson, David A., additional, Williams, Chris, additional, Masoli, Jane A.H., additional, Knight, Bridget A., additional, Jones, Christopher R., additional, Koshy, Cherian, additional, Ash, Amy, additional, Casey, Anna, additional, Bosworth, Andrew, additional, Ratcliffe, Liz, additional, Xu-McCrae, Li, additional, Pymont, Hannah M., additional, Hutchings, Stephanie, additional, Berry, Lisa, additional, Jones, Katie, additional, Halstead, Fenella, additional, Davis, Thomas, additional, Holmes, Christopher, additional, Iturriza-Gomara, Miren, additional, Lucaci, Anita O., additional, Randell, Paul Anthony, additional, Cox, Alison, additional, Madona, Pinglawathee, additional, Harris, Kathryn Ann, additional, Brown, Julianne Rose, additional, Mahungu, Tabitha W., additional, Irish-Tavares, Dianne, additional, Haque, Tanzina, additional, Hart, Jennifer, additional, Witele, Eric, additional, Fenton, Melisa Louise, additional, Liggett, Steven, additional, Graham, Clive, additional, Swindells, Emma, additional, Collins, Jennifer, additional, Eltringham, Gary, additional, Campbell, Sharon, additional, McClure, Patrick C., additional, Clark, Gemma, additional, Sloan, Tim J., additional, Jones, Carl, additional, Lynch, Jessica, additional, Warne, Ben, additional, Leonard, Steven, additional, Durham, Jillian, additional, Williams, Thomas, additional, Haldenby, Sam T., additional, Storey, Nathaniel, additional, Alikhan, Nabil-Fareed, additional, Holmes, Nadine, additional, Moore, Christopher, additional, Carlile, Matthew, additional, Perry, Malorie, additional, Craine, Noel, additional, Lyons, Ronan A., additional, Beckett, Angela H., additional, Goudarzi, Salman, additional, Fearn, Christopher, additional, Cook, Kate, additional, Dent, Hannah, additional, Paul, Hannah, additional, Davies, Robert, additional, Blane, Beth, additional, Girgis, Sophia T., additional, Beale, Mathew A., additional, Bellis, Katherine L., additional, Dorman, Matthew J., additional, Drury, Eleanor, additional, Kane, Leanne, additional, Kay, Sally, additional, McGuigan, Samantha, additional, Nelson, Rachel, additional, Prestwood, Liam, additional, Rajatileka, Shavanthi, additional, Batra, Rahul, additional, Williams, Rachel J., additional, Kristiansen, Mark, additional, Green, Angie, additional, Justice, Anita, additional, Mahanama, Adhyana I.K., additional, Samaraweera, Buddhini, additional, Hadjirin, Nazreen F., additional, Quick, Joshua, additional, Poplawski, Radoslaw, additional, Kermack, Leanne M., additional, Reynolds, Nicola, additional, Hall, Grant, additional, Chaudhry, Yasmin, additional, Pinckert, Malte L., additional, Georgana, Iliana, additional, Moll, Robin J., additional, Thornton, Alicia, additional, Myers, Richard, additional, Stockton, Joanne, additional, Williams, Charlotte A., additional, Yew, Wen C., additional, Trotter, Alexander J., additional, Trebes, Amy, additional, MacIntyre-Cockett, George, additional, Birchley, Alec, additional, Adams, Alexander, additional, Plimmer, Amy, additional, Gatica-Wilcox, Bree, additional, McKerr, Caoimhe, additional, Hilvers, Ember, additional, Jones, Hannah, additional, Asad, Hibo, additional, Coombes, Jason, additional, Evans, Johnathan M., additional, Fina, Laia, additional, Gilbert, Lauren, additional, Graham, Lee, additional, Cronin, Michelle, additional, Kumziene-Summerhayes, Sara, additional, Taylor, Sarah, additional, Jones, Sophie, additional, Groves, Danielle C., additional, Zhang, Peijun, additional, Gallis, Marta, additional, Louka, Stavroula F., additional, Starinskij, Igor, additional, Jackson, Chris, additional, Gourtovaia, Marina, additional, Tonkin-Hill, Gerry, additional, Lewis, Kevin, additional, Tovar-Corona, Jaime M., additional, James, Keith, additional, Baxter, Laura, additional, Alam, Mohammad T., additional, Orton, Richard J., additional, Hughes, Joseph, additional, Vattipally, Sreenu, additional, Ragonnet-Cronin, Manon, additional, Nascimento, Fabricia F., additional, Jorgensen, David, additional, Boyd, Olivia, additional, Geidelberg, Lily, additional, Zarebski, Alex E., additional, Raghwani, Jayna, additional, Kraemer, Moritz U.G., additional, Southgate, Joel, additional, Lindsey, Benjamin B., additional, Freeman, Timothy M., additional, Keatley, Jon-Paul, additional, Singer, Joshua B., additional, de Oliveira Martins, Leonardo, additional, Yeats, Corin A., additional, Abudahab, Khalil, additional, Taylor, Ben E.W., additional, Menegazzo, Mirko, additional, Danesh, John, additional, Hogsden, Wendy, additional, Eldirdiri, Sahar, additional, Kenyon, Anita, additional, Mason, Jenifer, additional, Robinson, Trevor I., additional, Holmes, Alison, additional, Price, James, additional, Hartley, John A., additional, Curran, Tanya, additional, Mather, Alison E., additional, Shankar, Giri, additional, Jones, Rachel, additional, Howe, Robin, additional, Morgan, Sian, additional, Wastenge, Elizabeth, additional, Chapman, Michael R., additional, Mookerjee, Siddharth, additional, Stanley, Rachael, additional, Smith, Wendy, additional, Peto, Timothy, additional, Eyre, David, additional, Crook, Derrick, additional, Vernet, Gabrielle, additional, Kitchen, Christine, additional, Gulliver, Huw, additional, Merrick, Ian, additional, Guest, Martyn, additional, Munn, Robert, additional, Bradley, Declan T., additional, Wyatt, Tim, additional, Beaver, Charlotte, additional, Foulser, Luke, additional, Palmer, Sophie, additional, Churcher, Carol M., additional, Brooks, Ellena, additional, Smith, Kim S., additional, Galai, Katerina, additional, McManus, Georgina M., additional, Bolt, Frances, additional, Coll, Francesc, additional, Meadows, Lizzie, additional, Attwood, Stephen W., additional, Davies, Alisha, additional, De Lacy, Elen, additional, Downing, Fatima, additional, Edwards, Sue, additional, Scarlett, Garry P., additional, Jeremiah, Sarah, additional, Smith, Nikki, additional, Leek, Danielle, additional, Sridhar, Sushmita, additional, Forrest, Sally, additional, Cormie, Claire, additional, Gill, Harmeet K., additional, Dias, Joana, additional, Higginson, Ellen E., additional, Maes, Mailis, additional, Young, Jamie, additional, Wantoch, Michelle, additional, Jamrozy, Dorota, additional, Lo, Stephanie, additional, Patel, Minal, additional, Hill, Verity, additional, Bewshea, Claire M., additional, Ellard, Sian, additional, Auckland, Cressida, additional, Harrison, Ian, additional, Bishop, Chloe, additional, Chalker, Vicki, additional, Richter, Alex, additional, Beggs, Andrew, additional, Best, Angus, additional, Percival, Benita, additional, Mirza, Jeremy, additional, Megram, Oliver, additional, Mayhew, Megan, additional, Crawford, Liam, additional, Ashcroft, Fiona, additional, Moles-Garcia, Emma, additional, Cumley, Nicola, additional, Hopes, Richard, additional, Asamaphan, Patawee, additional, Niebel, Marc O., additional, Gunson, Rory N., additional, Bradley, Amanda, additional, Maclean, Alasdair, additional, Mollett, Guy, additional, Blacow, Rachel, additional, Bird, Paul, additional, Helmer, Thomas, additional, Fallon, Karlie, additional, Tang, Julian, additional, Hale, Antony D., additional, Macfarlane-Smith, Louissa R., additional, Harper, Katherine L., additional, Carden, Holli, additional, Machin, Nicholas W., additional, Jackson, Kathryn A., additional, Ahmad, Shazaad S.Y., additional, George, Ryan P., additional, Turtle, Lance, additional, O’Toole, Elaine, additional, Watts, Joanne, additional, Breen, Cassie, additional, Cowell, Angela, additional, Alcolea-Medina, Adela, additional, Charalampous, Themoula, additional, Patel, Amita, additional, Levett, Lisa J., additional, Heaney, Judith, additional, Rowan, Aileen, additional, Taylor, Graham P., additional, Shah, Divya, additional, Atkinson, Laura, additional, Lee, Jack C.D., additional, Westhorpe, Adam P., additional, Jannoo, Riaz, additional, Lowe, Helen L., additional, Karamani, Angeliki, additional, Ensell, Leah, additional, Chatterton, Wendy, additional, Pusok, Monika, additional, Dadrah, Ashok, additional, Symmonds, Amanda, additional, Sluga, Graciela, additional, Molnar, Zoltan, additional, Baker, Paul, additional, Bonner, Stephen, additional, Essex, Sarah, additional, Barton, Edward, additional, Padgett, Debra, additional, Scott, Garren, additional, Greenaway, Jane, additional, Payne, Brendan A.I., additional, Burton-Fanning, Shirelle, additional, Waugh, Sheila, additional, Raviprakash, Veena, additional, Sheriff, Nicola, additional, Blakey, Victoria, additional, Williams, Lesley-Anne, additional, Moore, Jonathan, additional, Stonehouse, Susanne, additional, Smith, Louise, additional, Davidson, Rose K., additional, Bedford, Luke, additional, Coupland, Lindsay, additional, Wright, Victoria, additional, Chappell, Joseph G., additional, Tsoleridis, Theocharis, additional, Ball, Jonathan, additional, Khakh, Manjinder, additional, Fleming, Vicki M., additional, Lister, Michelle M., additional, Howson-Wells, Hannah C., additional, Berry, Louise, additional, Boswell, Tim, additional, Joseph, Amelia, additional, Willingham, Iona, additional, Duckworth, Nichola, additional, Walsh, Sarah, additional, Wise, Emma, additional, Moore, Nathan, additional, Mori, Matilde, additional, Cortes, Nick, additional, Kidd, Stephen, additional, Williams, Rebecca, additional, Gifford, Laura, additional, Bicknell, Kelly, additional, Wyllie, Sarah, additional, Lloyd, Allyson, additional, Impey, Robert, additional, Malone, Cassandra S., additional, Cogger, Benjamin J., additional, Levene, Nick, additional, Monaghan, Lynn, additional, Keeley, Alexander J., additional, Partridge, David G., additional, Raza, Mohammad, additional, Evans, Cariad, additional, Johnson, Kate, additional, Betteridge, Emma, additional, Farr, Ben W., additional, Goodwin, Scott, additional, Quail, Michael A., additional, Scott, Carol, additional, Shirley, Lesley, additional, Thurston, Scott A.J., additional, Rajan, Diana, additional, Bronner, Iraad F., additional, Aigrain, Louise, additional, Redshaw, Nicholas M., additional, Lensing, Stefanie V., additional, McCarthy, Shane, additional, Makunin, Alex, additional, Balcazar, Carlos E., additional, Gallagher, Michael D., additional, Williamson, Kathleen A., additional, Stanton, Thomas D., additional, Michelsen, Michelle L., additional, Warwick-Dugdale, Joanna, additional, Manley, Robin, additional, Farbos, Audrey, additional, Harrison, James W., additional, Sambles, Christine M., additional, Studholme, David J., additional, Lackenby, Angie, additional, Mbisa, Tamyo, additional, Platt, Steven, additional, Miah, Shahjahan, additional, Bibby, David, additional, Manso, Carmen, additional, Hubb, Jonathan, additional, Dabrera, Gavin, additional, Ramsay, Mary, additional, Bradshaw, Daniel, additional, Schaefer, Ulf, additional, Groves, Natalie, additional, Gallagher, Eileen, additional, Lee, David, additional, Williams, David, additional, Ellaby, Nicholas, additional, Hartman, Hassan, additional, Manesis, Nikos, additional, Patel, Vineet, additional, Ledesma, Juan, additional, Twohig, Katherine A., additional, Allara, Elias, additional, Pearson, Clare, additional, Cheng, Jeffrey K.J., additional, Bridgewater, Hannah E., additional, Frost, Lucy R., additional, Taylor-Joyce, Grace, additional, Brown, Paul E., additional, Tong, Lily, additional, Broos, Alice, additional, Mair, Daniel, additional, Nichols, Jenna, additional, Carmichael, Stephen N., additional, Smollett, Katherine L., additional, Nomikou, Kyriaki, additional, Aranday-Cortes, Elihu, additional, Johnson, Natasha, additional, Nickbakhsh, Seema, additional, Vamos, Edith E., additional, Hughes, Margaret, additional, Rainbow, Lucille, additional, Eccles, Richard, additional, Nelson, Charlotte, additional, Whitehead, Mark, additional, Gregory, Richard, additional, Gemmell, Matthew, additional, Wierzbicki, Claudia, additional, Webster, Hermione J., additional, Fisher, Chloe L., additional, Signell, Adrian W., additional, Betancor, Gilberto, additional, Wilson, Harry D., additional, Nebbia, Gaia, additional, Flaviani, Flavia, additional, Cerda, Alberto C., additional, Merrill, Tammy V., additional, Wilson, Rebekah E., additional, Cotic, Marius, additional, Bayzid, Nadua, additional, Thompson, Thomas, additional, Acheson, Erwan, additional, Rushton, Steven, additional, O’Brien, Sarah, additional, Baker, David J., additional, Rudder, Steven, additional, Aydin, Alp, additional, Sang, Fei, additional, Debebe, Johnny, additional, Francois, Sarah, additional, Vasylyeva, Tetyana I., additional, Zamudio, Marina Escalera, additional, Gutierrez, Bernardo, additional, Marchbank, Angela, additional, Maksimovic, Joshua, additional, Spellman, Karla, additional, McCluggage, Kathryn, additional, Morgan, Mari, additional, Beer, Robert, additional, Afifi, Safiah, additional, Workman, Trudy, additional, Fuller, William, additional, Bresner, Catherine, additional, Angyal, Adrienn, additional, Green, Luke R., additional, Parsons, Paul J., additional, Tucker, Rachel M., additional, Brown, Rebecca, additional, Whiteley, Max, additional, Bonfield, James, additional, Puethe, Christoph, additional, Whitwham, Andrew, additional, Liddle, Jennifier, additional, Rowe, Will, additional, Siveroni, Igor, additional, Le-Viet, Thanh, additional, Gaskin, Amy, additional, Johnson, Rob, additional, Abnizova, Irina, additional, Ali, Mozam, additional, Allen, Laura, additional, Anderson, Ralph, additional, Ariani, Cristina, additional, Austin-Guest, Siobhan, additional, Bala, Sendu, additional, Barrett, Jeffrey, additional, Bassett, Andrew, additional, Battleday, Kristina, additional, Beal, James, additional, Beale, Mathew, additional, Bellany, Sam, additional, Bellerby, Tristram, additional, Bellis, Katie, additional, Berger, Duncan, additional, Berriman, Matt, additional, Bevan, Paul, additional, Binley, Simon, additional, Bishop, Jason, additional, Blackburn, Kirsty, additional, Boughton, Nick, additional, Bowker, Sam, additional, Brendler-Spaeth, Timothy, additional, Bronner, Iraad, additional, Brooklyn, Tanya, additional, Buddenborg, Sarah Kay, additional, Bush, Robert, additional, Caetano, Catarina, additional, Cagan, Alex, additional, Carter, Nicola, additional, Cartwright, Joanna, additional, Monteiro, Tiago Carvalho, additional, Chapman, Liz, additional, Chillingworth, Tracey-Jane, additional, Clapham, Peter, additional, Clark, Richard, additional, Clarke, Adrian, additional, Clarke, Catriona, additional, Cole, Daryl, additional, Cook, Elizabeth, additional, Coppola, Maria, additional, Cornell, Linda, additional, Cornwell, Clare, additional, Corton, Craig, additional, Crackett, Abby, additional, Cranage, Alison, additional, Craven, Harriet, additional, Craw, Sarah, additional, Crawford, Mark, additional, Cutts, Tim, additional, Dabrowska, Monika, additional, Davies, Matt, additional, Dawson, Joseph, additional, Day, Callum, additional, Densem, Aiden, additional, Dibling, Thomas, additional, Dockree, Cat, additional, Dodd, David, additional, Dogga, Sunil, additional, Dorman, Matthew, additional, Dougan, Gordon, additional, Dougherty, Martin, additional, Dove, Alexander, additional, Drummond, Lucy, additional, Dudek, Monika, additional, Durrant, Laura, additional, Easthope, Elizabeth, additional, Eckert, Sabine, additional, Ellis, Pete, additional, Farr, Ben, additional, Fenton, Michael, additional, Ferrero, Marcella, additional, Flack, Neil, additional, Fordham, Howerd, additional, Forsythe, Grace, additional, Francis, Matt, additional, Fraser, Audrey, additional, Freeman, Adam, additional, Galvin, Anastasia, additional, Garcia-Casado, Maria, additional, Gedny, Alex, additional, Girgis, Sophia, additional, Glover, James, additional, Gould, Oliver, additional, Gray, Andy, additional, Gray, Emma, additional, Griffiths, Coline, additional, Gu, Yong, additional, Guerin, Florence, additional, Hamilton, Will, additional, Hanks, Hannah, additional, Harrison, Ewan, additional, Harrott, Alexandria, additional, Harry, Edward, additional, Harvison, Julia, additional, Heath, Paul, additional, Hernandez-Koutoucheva, Anastasia, additional, Hobbs, Rhiannon, additional, Holland, Dave, additional, Holmes, Sarah, additional, Hornett, Gary, additional, Hough, Nicholas, additional, Huckle, Liz, additional, Hughes-Hallet, Lena, additional, Hunter, Adam, additional, Inglis, Stephen, additional, Iqbal, Sameena, additional, Jackson, Adam, additional, Jackson, David, additional, Verdejo, Carlos Jimenez, additional, Jones, Matthew, additional, Kallepally, Kalyan, additional, Kay, Keely, additional, Keatley, Jon, additional, Keith, Alan, additional, King, Alison, additional, Kitchin, Lucy, additional, Kleanthous, Matt, additional, Klimekova, Martina, additional, Korlevic, Petra, additional, Krasheninnkova, Ksenia, additional, Lane, Greg, additional, Langford, Cordelia, additional, Laverack, Adam, additional, Law, Katharine, additional, Lensing, Stefanie, additional, Lewis-Wade, Amanah, additional, Liddle, Jennifer, additional, Lin, Quan, additional, Lindsay, Sarah, additional, Linsdell, Sally, additional, Long, Rhona, additional, Lovell, Jamie, additional, Lovell, Jon, additional, Mack, James, additional, Maddison, Mark, additional, Makunin, Aleksei, additional, Mamun, Irfan, additional, Mansfield, Jenny, additional, Marriott, Neil, additional, Martin, Matt, additional, Mayho, Matthew, additional, McClintock, Jo, additional, McHugh, Sandra, additional, MapcMinn, Liz, additional, Meadows, Carl, additional, Mobley, Emily, additional, Moll, Robin, additional, Morra, Maria, additional, Morrow, Leanne, additional, Murie, Kathryn, additional, Nash, Sian, additional, Nathwani, Claire, additional, Naydenova, Plamena, additional, Neaverson, Alexandra, additional, Nerou, Ed, additional, Nicholson, Jon, additional, Nimz, Tabea, additional, Noell, Guillaume G., additional, O’Meara, Sarah, additional, Ohan, Valeriu, additional, Olney, Charles, additional, Ormond, Doug, additional, Oszlanczi, Agnes, additional, Pang, Yoke Fei, additional, Pardubska, Barbora, additional, Park, Naomi, additional, Parmar, Aaron, additional, Patel, Gaurang, additional, Payne, Maggie, additional, Peacock, Sharon, additional, Petersen, Arabella, additional, Plowman, Deborah, additional, Preston, Tom, additional, Quail, Michael, additional, Rance, Richard, additional, Rawlings, Suzannah, additional, Redshaw, Nicholas, additional, Reynolds, Joe, additional, Reynolds, Mark, additional, Rice, Simon, additional, Richardson, Matt, additional, Roberts, Connor, additional, Robinson, Katrina, additional, Robinson, Melanie, additional, Robinson, David, additional, Rogers, Hazel, additional, Rojo, Eduardo Martin, additional, Roopra, Daljit, additional, Rose, Mark, additional, Rudd, Luke, additional, Sadri, Ramin, additional, Salmon, Nicholas, additional, Saul, David, additional, Schwach, Frank, additional, Seekings, Phil, additional, Simms, Alison, additional, Sinnott, Matt, additional, Sivadasan, Shanthi, additional, Siwek, Bart, additional, Sizer, Dale, additional, Skeldon, Kenneth, additional, Skelton, Jason, additional, Slater-Tunstill, Joanna, additional, Sloper, Lisa, additional, Smerdon, Nathalie, additional, Smith, Chris, additional, Smith, Christen, additional, Smith, James, additional, Smith, Katie, additional, Smith, Michelle, additional, Smith, Sean, additional, Smith, Tina, additional, Sneade, Leighton, additional, Soria, Carmen Diaz, additional, Sousa, Catarina, additional, Souster, Emily, additional, Sparkes, Andrew, additional, Spencer-Chapman, Michael, additional, Squares, Janet, additional, Stanley, Robert, additional, Steed, Claire, additional, Stickland, Tim, additional, Still, Ian, additional, Stratton, Mike, additional, Strickland, Michelle, additional, Swann, Allen, additional, Swiatkowska, Agnieszka, additional, Sycamore, Neil, additional, Swift, Emma, additional, Symons, Edward, additional, Szluha, Suzanne, additional, Taluy, Emma, additional, Tao, Nunu, additional, Taylor, Katy, additional, Taylor, Sam, additional, Thompson, Stacey, additional, Thompson, Mark, additional, Thomson, Mark, additional, Thomson, Nicholas, additional, Thurston, Scott, additional, Toombs, Dee, additional, Topping, Benjamin, additional, Tovar-Corona, Jaime, additional, Ungureanu, Daniel, additional, Uphill, James, additional, Urbanova, Jana, additional, Van, Philip Jansen, additional, Vancollie, Valerie, additional, Voak, Paul, additional, Walker, Danielle, additional, Walker, Matthew, additional, Waller, Matt, additional, Ward, Gary, additional, Weatherhogg, Charlie, additional, Webb, Niki, additional, Wells, Alan, additional, Wells, Eloise, additional, Westwood, Luke, additional, Whipp, Theo, additional, Whiteley, Thomas, additional, Whitton, Georgia, additional, Widaa, Sara, additional, Williams, Mia, additional, Wilson, Mark, additional, and Wright, Sean, additional

Published
2021
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27. The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769

Author

Howe, Kerstin, primary, Dwinell, Melinda, additional, Shimoyama, Mary, additional, Corton, Craig, additional, Betteridge, Emma, additional, Dove, Alexander, additional, Quail, Michael A., additional, Smith, Michelle, additional, Saba, Laura, additional, Williams, Robert W., additional, Chen, Hao, additional, Kwitek, Anne E., additional, McCarthy, Shane A., additional, Uliano-Silva, Marcela, additional, Chow, William, additional, Tracey, Alan, additional, Torrance, James, additional, Sims, Ying, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, and Blaxter, Mark, additional

Published
2021
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28. The genome sequence of the common pipistrelle, Pipistrellus pipistrellus Schreber 1774

Author

Vine, Christopher, primary, Teeling, Emma C., additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Doulcan, Jale, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Howe, Kerstin, additional, Torrance, James, additional, Wood, Jonathan, additional, Pelan, Sarah, additional, Sims, Ying, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, Mead, Daniel, additional, and Blaxter, Mark, additional

Published
2021
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29. The genome sequence of the European golden eagle, Aquila chrysaetos chrysaetos Linnaeus 1758

Author

Mead, Dan, primary, Ogden, Rob, additional, Meredith, Anna, additional, Peniche, Gabriela, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Doulcan, Jale, additional, Holmes, Nadine, additional, Wright, Victoria, additional, Loose, Matt, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Howe, Kerstin, additional, Chow, William, additional, Torrance, James, additional, Collins, Joanna, additional, Challis, Richard, additional, Durbin, Richard, additional, and Blaxter, Mark, additional

Published
2021
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30. The genome sequence of the brown trout, Salmo trutta Linnaeus 1758

Author

Hansen, Tom, primary, Fjelldal, Per Gunnar, additional, Lien, Sigbjørn, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Doulcan, Jale, additional, Fedrigo, Olivier, additional, Mountcastle, Jacquelyn, additional, Jarvis, Erich, additional, McCarthy, Shane A., additional, Chow, William, additional, Howe, Kerstin, additional, Torrance, James, additional, Wood, Jonathan, additional, Sims, Ying, additional, Haggerty, Leanne, additional, Challis, Richard, additional, Threlfall, Jonathan, additional, Mead, Daniel, additional, Durbin, Richard, additional, and Blaxter, Mark, additional

Published
2021
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31. Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation

Author

Bentley, Stephen D., Corton, Craig, Brown, Susan E., Barron, Andrew, Clark, Louise, Doggett, Jon, Harris, Barbara, Ormond, Doug, Quail, Michael A., May, Georgiana, Francis, David, Knudson, Dennis, Parkhill, Julian, and Ishimaru, Carol A.

Subjects
Bacteria, Pathogenic -- Genetic aspects, Niche (Ecology) -- Genetic aspects, Biological sciences
Abstract

Clavibacter michiganensis subsp, sepedonicus is a plant-pathogenic bacterium and the causative agent of bacterial ring rot, a devastating agricultural disease under strict quarantine control and zero tolerance in the seed potato industry. This organism appears to be largely restricted to an endophytic lifestyle, proliferating within plant tissues and unable to persist in the absence of plant material. Analysis of the genome sequence of C. michiganensis subsp, sepedonicus and comparison with the genome sequences of related plant pathogens revealed a dramatic recent evolutionary history. The genome contains 106 insertion sequence elements, which appear to have been active in extensive rearrangement of the chromosome compared to that of Clavibacter michiganensis subsp, michiganensis. There are 110 pseudogenes with overrepresentation in functions associated with carbohydrate metabolism, transcriptional regulation, and pathogenicity. Genome comparisons also indicated that there is substantial gene content diversity within the species, probably due to differential gene acquisition and loss. These genomic features and evolutionary dating suggest that there was recent adaptation for life in a restricted niche where nutrient diversity and perhaps competition are low, correlated with a reduced ability to exploit previously occupied complex niches outside the plant. Toleration of factors such as multiplication and integration of insertion sequence elements, genome rearrangements, and functional disruption of many genes and operons seems to indicate that there has been general relaxation of selective pressure on a large proportion of the genome.

Published
2008

32. The genome sequence of the Eurasian river otter, Lutra lutra Linnaeus 1758 [version 1; peer review: 2 approved]

Author

Mead, Dan, Hailer, Frank, Chadwick, Elisabeth, Portela Miguez, Roberto, Smith, Michelle, Corton, Craig, Oliver, Karen, Skelton, Jason, Betteridge, Emma, Doulcan, Jale Doulcan, Dudchenko, Olga, Omer, Arina, Weisz, David, Lieberman Aiden, Erez, McCarthy, Shane, Howe, Kerstin, Sims, Ying, Torrance, James, Tracey, Alan, Challis, Richard, Durbin, Richard, and Blaxter, Mark

Subjects
lcsh:R, lcsh:Medicine, lcsh:Q, lcsh:Science
Abstract

We present a genome assembly from an individual male Lutra lutra (the Eurasian river otter; Vertebrata; Mammalia; Eutheria; Carnivora; Mustelidae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules, with both X and Y sex chromosomes assembled.

Published
2020

33. Using de novo assembly to identify structural variation of complex immune system gene regions

Author

Zhang, Jia-Yuan, primary, Roberts, Hannah, additional, Flores, David S. C., additional, Cutler, Antony J., additional, Brown, Andrew C., additional, Whalley, Justin P., additional, Mielczarek, Olga, additional, Buck, David, additional, Lockstone, Helen, additional, Xella, Barbara, additional, Oliver, Karen, additional, Corton, Craig, additional, Betteridge, Emma, additional, Bashford-Rogers, Rachael, additional, Knight, Julian C., additional, Todd, John A., additional, and Band, Gavin, additional

Published
2021
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34. Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance

Author

Holden, Matthew T.G., Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Day, Nicholas P.J., Enright, Mark C., Foster, Tim J., Moore, Catrin E., Hurst, Laurence, Atkin, Rebecca, Barron, Andrew, Bason, Nathalie, Bentley, Stephen D., Chillingworth, Carol, Chillingworth, Tracey, Churcher, Carol, Clark, Louise, Corton, Craig, Cronin, Ann, Doggett, Jon, Dowd, Linda, Feltwell, Theresa, Hance, Zahra, Harris, Barbara C., Bishop, Hauser, Heidi, Holroyd, Simon, Jagels, Kay, James, Keith D., Lennard, Nicola, Line, Alexandra, Mayes, Rebecca, Moule, Sharon, Mungall, Karen, Ormond, Douglas, Quail, Michael A., Rabbinowitsch, Ester, Rutherford, Kim, Sanders, Mandy, Sharp, Sarah, Simmonds, Mark, Stevens, Kim, Whitehead, Sally, Barrell, Bart G., Spratt, Brian G., and Parkhill, Julian

Subjects
Drug resistance in microorganisms -- Research, Staphylococcus aureus -- Research, Staphylococcus aureus -- Genetic aspects, Science and technology, National Academy of Sciences -- Research
Abstract

Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major and constantly changing clinical challenge. We sequenced the [approximately equal to] 2.8-Mbp genomes of two disease-causing S. aureus strains isolated from distinct clinical settings: a recent hospital-acquired representative of the epidemic methicillin-resistant S. aureus EMRSA-16 clone (MRSA252), a clinically important and globally prevalent lineage; and a representative of an invasive community-acquired methicillin-susceptible S. aureus clone (MSSA476). A comparative-genomics approach was used to explore the mechanisms of evolution of clinically important S, aureus genomes and to identify regions affecting virulence and drug resistance. The genome sequences of MRSA252 and MSSA476 have a well conserved core region but differ markedly in their accessory genetic elements. MRSA252 is the most genetically diverse S. aureus strain sequenced to date: [approximately equal to] 6% of the genome is novel compared with other published genomes, and it contains several unique genetic elements. MSSA476 is methicillin-susceptible, but it contains a novel Staphylococcal chromosomal cassette (SCC) mec-like element (designated SC[C.sub.476]), which is integrated at the same site on the chromosome as SCCmec elements in MRSA strains but encodes a putative fusidic acid resistance protein. The crucial role that accessory elements play in the rapid evolution of S. aureus is clearly illustrated by comparing the MSSA476 genome with that of an extremely closely related MRSA community-acquired strain; the differential distribution of large mobile elements carrying virulence and drug-resistance determinants may be responsible for the clinically important phenotypic differences in these strains.

Published
2004

35. The gene-rich genome of the scallop Pecten maximus

Author

Kenny, Nathan J, primary, McCarthy, Shane A, primary, Dudchenko, Olga, primary, James, Katherine, primary, Betteridge, Emma, primary, Corton, Craig, primary, Dolucan, Jale, primary, Mead, Dan, primary, Oliver, Karen, primary, Omer, Arina D, primary, Pelan, Sarah, primary, Ryan, Yan, primary, Sims, Ying, primary, Skelton, Jason, primary, Smith, Michelle, primary, Torrance, James, primary, Weisz, David, primary, Wipat, Anil, primary, Aiden, Erez L, primary, Howe, Kerstin, primary, and Williams, Suzanne T, primary

Published
2020
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37. The genome sequence of the eastern grey squirrel, Sciurus carolinensis Gmelin, 1788

Author

Mead, Dan, primary, Fingland, Kathryn, additional, Cripps, Rachel, additional, Portela Miguez, Roberto, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Doulcan, Jale, additional, Quail, Michael A., additional, McCarthy, Shane A., additional, Howe, Kerstin, additional, Sims, Ying, additional, Torrance, James, additional, Tracey, Alan, additional, Challis, Richard, additional, Durbin, Richard, additional, and Blaxter, Mark, additional

Published
2020
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38. The genome sequence of the Eurasian red squirrel, Sciurus vulgaris Linnaeus 1758

Author

Mead, Daniel, primary, Fingland, Kathryn, additional, Cripps, Rachel, additional, Portela Miguez, Roberto, additional, Smith, Michelle, additional, Corton, Craig, additional, Oliver, Karen, additional, Skelton, Jason, additional, Betteridge, Emma, additional, Dolucan, Jale, additional, Dudchenko, Olga, additional, Omer, Arina D., additional, Weisz, David, additional, Lieberman Aiden, Erez, additional, Fedrigo, Olivier, additional, Mountcastle, Jacquelyn, additional, Jarvis, Erich, additional, McCarthy, Shane A., additional, Sims, Ying, additional, Torrance, James, additional, Tracey, Alan, additional, Howe, Kerstin, additional, Challis, Richard, additional, Durbin, Richard, additional, and Blaxter, Mark, additional

Published
2020
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39. The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Author

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., Gerrard, Caroline S., Atkin, Rebecca J., Barron, Andrew J., Bowman, Sharen, Bray-Allen, Sarah P., Bringaud, Frédéric, Clark, Louise N., Corton, Craig H., Cronin, Ann, Davies, Robert, Doggett, Jonathon, Fraser, Audrey, Grüter, Eric, Hall, Sarah, Harper, A. David, Kay, Mike P., Leech, Vanessa, Mayes, Rebecca, Price, Claire, Quail, Michael A., Rabbinowitsch, Ester, Reitter, Christopher, Rutherford, Kim, Sasse, Jürgen, Sharp, Sarah, Shownkeen, Ratna, MacLeod, Annette, Taylor, Sonya, Tweedie, Alison, Turner, C. Michael R., Tait, Andrew, Gull, Keith, Barrell, Bart, and Melville, Sara E.

Published
2003

40. Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens

Author

Churcher Carol, Simmonds Mark, Smith Frances, Bason Nathalie, Mayho Matthew, Ormond Douglas, Clark Louise, Bignell Alexandra, Barron Andrew, Vlisidou Isabella, Sanchez-Contreras Maria, Corton Craig, Crossman Lisa, Waterfield Nicholas R, Wilkinson Paul, Harris David, Thompson Nicholas R, Quail Michael, Parkhill Julian, and ffrench-Constant Richard H

Subjects
Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background The Gram-negative bacterium Photorhabdus asymbiotica (Pa) has been recovered from human infections in both North America and Australia. Recently, Pa has been shown to have a nematode vector that can also infect insects, like its sister species the insect pathogen P. luminescens (Pl). To understand the relationship between pathogenicity to insects and humans in Photorhabdus we have sequenced the complete genome of Pa strain ATCC43949 from North America. This strain (formerly referred to as Xenorhabdus luminescens strain 2) was isolated in 1977 from the blood of an 80 year old female patient with endocarditis, in Maryland, USA. Here we compare the complete genome of Pa ATCC43949 with that of the previously sequenced insect pathogen P. luminescens strain TT01 which was isolated from its entomopathogenic nematode vector collected from soil in Trinidad and Tobago. Results We found that the human pathogen Pa had a smaller genome (5,064,808 bp) than that of the insect pathogen Pl (5,688,987 bp) but that each pathogen carries approximately one megabase of DNA that is unique to each strain. The reduced size of the Pa genome is associated with a smaller diversity in insecticidal genes such as those encoding the Toxin complexes (Tc's), Makes caterpillars floppy (Mcf) toxins and the Photorhabdus Virulence Cassettes (PVCs). The Pa genome, however, also shows the addition of a plasmid related to pMT1 from Yersinia pestis and several novel pathogenicity islands including a novel Type Three Secretion System (TTSS) encoding island. Together these data suggest that Pa may show virulence against man via the acquisition of the pMT1-like plasmid and specific effectors, such as SopB, that promote its persistence inside human macrophages. Interestingly the loss of insecticidal genes in Pa is not reflected by a loss of pathogenicity towards insects. Conclusion Our results suggest that North American isolates of Pa have acquired virulence against man via the acquisition of a plasmid and specific virulence factors with similarity to those shown to play roles in pathogenicity against humans in other bacteria.

Published
2009
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41. Genome Diversity of Epstein-Barr Virus from Multiple Tumor Types and Normal Infection

Author

Palser, Anne L., primary, Grayson, Nicholas E., additional, White, Robert E., additional, Corton, Craig, additional, Correia, Samantha, additional, Ba abdullah, Mohammed M., additional, Watson, Simon J., additional, Cotten, Matthew, additional, Arrand, John R., additional, Murray, Paul G., additional, Allday, Martin J., additional, Rickinson, Alan B., additional, Young, Lawrence S., additional, Farrell, Paul J., additional, and Kellam, Paul, additional

Published
2015
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44. Description and Nomenclature ofNeisseria meningitidisCapsule Locus

Author

Harrison, Odile B., primary, Claus, Heike, additional, Jiang, Ying, additional, Bennett, Julia S., additional, Bratcher, Holly B., additional, Jolley, Keith A., additional, Corton, Craig, additional, Care, Rory, additional, Poolman, Jan T., additional, Zollinger, Wendell D., additional, Frasch, Carl E., additional, Stephens, David S., additional, Feavers, Ian, additional, Frosch, Matthias, additional, Parkhill, Julian, additional, Vogel, Ulrich, additional, Quail, Michael A., additional, Bentley, Stephen D., additional, and Maiden, Martin C.J., additional

Published
2013
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46. Citrobacter rodentium is an Unstable Pathogen Showing Evidence of Significant Genomic Flux

Author

Petty, Nicola K., primary, Feltwell, Theresa, additional, Pickard, Derek, additional, Clare, Simon, additional, Toribio, Ana L., additional, Fookes, Maria, additional, Roberts, Kevin, additional, Monson, Rita, additional, Nair, Satheesh, additional, Kingsley, Robert A., additional, Bulgin, Richard, additional, Wiles, Siouxsie, additional, Goulding, David, additional, Keane, Thomas, additional, Corton, Craig, additional, Lennard, Nicola, additional, Harris, David, additional, Willey, David, additional, Rance, Richard, additional, Yu, Lu, additional, Choudhary, Jyoti S., additional, Churcher, Carol, additional, Quail, Michael A., additional, Parkhill, Julian, additional, Frankel, Gad, additional, Dougan, Gordon, additional, Salmond, George P. C., additional, and Thomson, Nicholas R., additional

Published
2011
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47. Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens

Author

Wilkinson, Paul, primary, Waterfield, Nicholas R, additional, Crossman, Lisa, additional, Corton, Craig, additional, Sanchez-Contreras, Maria, additional, Vlisidou, Isabella, additional, Barron, Andrew, additional, Bignell, Alexandra, additional, Clark, Louise, additional, Ormond, Douglas, additional, Mayho, Matthew, additional, Bason, Nathalie, additional, Smith, Frances, additional, Simmonds, Mark, additional, Churcher, Carol, additional, Harris, David, additional, Thompson, Nicholas R, additional, Quail, Michael, additional, Parkhill, Julian, additional, and ffrench-Constant, Richard H, additional

Published
2009
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48. Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

Author

Stabler, Richard A, primary, He, Miao, additional, Dawson, Lisa, additional, Martin, Melissa, additional, Valiente, Esmeralda, additional, Corton, Craig, additional, Lawley, Trevor D, additional, Sebaihia, Mohammed, additional, Quail, Michael A, additional, Rose, Graham, additional, Gerding, Dale N, additional, Gibert, Maryse, additional, Popoff, Michel R, additional, Parkhill, Julian, additional, Dougan, Gordon, additional, and Wren, Brendan W, additional

Published
2009
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