240 results on '"Corsaro, Alessandro"'
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2. Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity
3. Antitumor Potential of Antiepileptic Drugs in Human Glioblastoma: Pharmacological Targets and Clinical Benefits
4. Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons
5. Proteostasis unbalance in prion diseases: Mechanisms of neurodegeneration and therapeutic targets
6. In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity
7. Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death
8. Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells
9. N6-Isopentenyladenosine Hinders the Vasculogenic Mimicry in Human Glioblastoma Cells through Src-120 Catenin Pathway Modulation and RhoA Activity Inhibition
10. Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment
11. Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity
12. Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231
13. Expression of Somatostatin Receptor mRNA in Human Meningiomas and their Implication in in vitro Antiproliferative Activity
14. Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells
15. Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells
16. Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants
17. ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation
18. Amino-Terminally Truncated Prion Protein PrP90-231 Induces Microglial Activation in Vitro
19. Amyloid Precursor Protein and Presenilin 1 Interaction Studied by FRET in Human H4 Cells
20. Amyloid Precursor Protein Modulates ERK-1 and -2 Signaling
21. SDF-1 Controls Pituitary Cell Proliferation through the Activation of ERK1/2 and the Ca2+-Dependent, Cytosolic Tyrosine Kinase Pyk2
22. Characterization of the Proapoptotic Intracellular Mechanisms Induced by a Toxic Conformer of the Recombinant Human Prion Protein Fragment 90–231
23. Somatostatin Receptor Subtype-Dependent Regulation of Nitric Oxide Release: Involvement of Different Intracellular Pathways
24. The Phosphotyrosine Phosphatase η Mediates Somatostatin Inhibition of Glioma Proliferation via the Dephosphorylation of ERK1/2
25. Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro
26. Contribution of two conserved glycine residues to fibrillogenesis of the 106–126 prion protein fragment. Evidence that a soluble variant of the 106–126 peptide is neurotoxic
27. In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas
28. Nitric Oxide Production Stimulated by the Basic Fibroblast Growth Factor Requires the Synthesis of Ceramide
29. The Activation of the Phosphotyrosine Phosphatase η (r-PTPη) Is Responsible for the Somatostatin Inhibition of PC Cl3 Thyroid Cell Proliferation
30. Canine osteosarcoma cell lines contain stem-like cancer cells : biological and pharmacological characterization
31. Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity
32. p38 MAP Kinase Mediates the Cell Death Induced by PrP106–126 in the SH-SY5Y Neuroblastoma Cells
33. Apoptotic Cell Death and Impairment of L-Type Voltage-Sensitive Calcium Channel Activity in Rat Cerebellar Granule Cells Treated with the Prion Protein Fragment 106–126
34. Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity
35. Unraveling the amyloid beta attraction for the prion protein
36. Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors
37. ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE
38. Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System
39. A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates
40. Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells
41. Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm
42. Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231
43. New therapeutic strategies for Alzheimer’s disease by determination of structure and toxicity of oligomeric beta-amyloids aggregation states
44. Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation
45. Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells
46. Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231 (hPrP90-231), as possible mechanism of its neurotoxic effects
47. Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform
48. Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities'
49. Molecular mechanism involved in the aggregation and fibril formation of the recombinant human prion fragment PrP 90-231
50. The activation of the phosphotyrosine phosphatase h (r-PTPh) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation
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