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Your search keyword '"Corner, Adam S."' showing total 5 results
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5 results on '"Corner, Adam S."'

1. Contrived Materials and a Data Set for the Evaluation of Liquid Biopsy Tests

Author

Hernandez, Kyle M., primary, Bramlett, Kelli S., additional, Agius, Phaedra, additional, Baden, Jonathan, additional, Cao, Ru, additional, Clement, Omoshile, additional, Corner, Adam S., additional, Craft, Jonathan, additional, Dean, Dennis A., additional, Dry, Jonathan R., additional, Grigaityte, Kristina, additional, Grossman, Robert L., additional, Hicks, James, additional, Higa, Nikki, additional, Holzer, Timothy R., additional, Jensen, Jeffrey, additional, Johann, Donald J., additional, Katz, Sigrid, additional, Kolatkar, Anand, additional, Keynton, Jennifer L., additional, Lee, Jerry S.H., additional, Maar, Dianna, additional, Martini, Jean-Francois, additional, Meyer, Christopher G., additional, Roberts, Peter C., additional, Ryder, Matt, additional, Salvatore, Lea, additional, Schageman, Jeoffrey J., additional, Somiari, Stella, additional, Stetson, Daniel, additional, Stern, Mark, additional, Xu, Liya, additional, and Leiman, Lauren C., additional

Published
2023
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3. Catalytic mechanism of the quinoenzyme amine oxidase from Escherichia coli: exploring the reductive half-reaction

Author

Wilmot, Carrie M., Murray, Jeremy M., Alton, Gordon, Parsons, Mark R., Convery, Maire A., Blakeley, Veronica, Corner, Adam S., Palcic, Monica M., Knowles, Peter F., McPherson, Michael J., and Phillips, Simon E.V.

Subjects
X-ray crystallography -- Methods, Mutagenesis -- Methods, Escherichia coli -- Research, Oxidases -- Research, Enzymes -- Research, Biological sciences, Chemistry
Abstract

A crystallographic structural analysis with subsequent mutagenesis study of the complex composed of the inhibitor 2-hydrazinopyridine and Escherichia coli amine oxidase (ECAO) was done to elucidate the identity of the catalytic base and the mode of substrate binding. Asp 383 was identified as the catalytic general base. Substrate binding, on the other hand, was observed to occur at the tip of the pyridine ring located at the molecular interface between D3 and D4. Fuller understanding of the activities of ECAO can be achieved with further studies about the redox chemistry involved.

Published
1997

4. Detection of Actionable BCR-ABL1 Kinase Domain (KD) Mutations in Chronic Myeloid Leukemia (CML) Patients with Failure and Warning Response to Tyrosine Kinase Inhibitors (TKIs): Potential Impact of Next-Generation Sequencing (NGS) and Droplet Digital PCR (ddPCR) on Clinical Decision Making

Author

Soverini, Simona, primary, Martelli, Margherita, primary, Bavaro, Luana, primary, De Benedittis, Caterina, primary, Iurlo, Alessandra, primary, Galimberti, Sara, primary, Pregno, Patrizia, primary, Bonifacio, Massimiliano, primary, Lunghi, Francesca, primary, Castagnetti, Fausto, primary, Gugliotta, Gabriele, primary, Rosti, Gianantonio, primary, Tiribelli, Mario, primary, Velotta, Vanessa, primary, Stagno, Fabio, primary, Russo Rossi, Antonella, primary, D'Adda, Mariella, primary, Baratè, Claudia, primary, Crugnola, Monica, primary, Luciano, Luigiana, primary, Laginestra, Maria Antonella, primary, Corner, Adam S, primary, Maar, Dianna, primary, Percesepe, Antonio, primary, Pileri, Stefano, primary, Pane, Fabrizio, primary, Saglio, Giuseppe, primary, Baccarani, Michele, primary, Martinelli, Giovanni, primary, and Cavo, Michele, primary

Published
2019
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