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4. Risk Factors for Anaplastic Thyroid Carcinoma: A Case Series From a Tertiary Referral Center for Thyroid Surgery and Literature Analysis

Author

Graceffa, Giuseppa, primary, Salamone, Giuseppe, additional, Contino, Silvia, additional, Saputo, Federica, additional, Corigliano, Alessandro, additional, Melfa, Giuseppina, additional, Proclamà, Maria Pia, additional, Richiusa, Pierina, additional, Mazzola, Sergio, additional, Tutino, Roberta, additional, Orlando, Giuseppina, additional, and Scerrino, Gregorio, additional

Published
2022
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5. Papillary Thyroid Microcarcinoma: Active Surveillance Against Surgery. Considerations of an Italian Working Group From a Systematic Review

Author

Orlando, Giuseppina, primary, Scerrino, Gregorio, additional, Corigliano, Alessandro, additional, Vitale, Irene, additional, Tutino, Roberta, additional, Radellini, Stefano, additional, Cupido, Francesco, additional, Graceffa, Giuseppa, additional, Cocorullo, Gianfranco, additional, Salamone, Giuseppe, additional, and Melfa, Giuseppina, additional

Published
2022
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6. Chronic asthenia in patients who have undergone endocrine neck surgery

Author

Scerrino, Gregorio, primary, Melfa, Giuseppina, additional, Lo Brutto, Daniela, additional, Mazzola, Sergio, additional, Corigliano, Alessandro, additional, Vitale, Irene, additional, Tutino, Roberta, additional, Rotolo, Giulia, additional, Orlando, Giuseppina, additional, and Cocorullo, Gianfranco, additional

Published
2021
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7. Predictors of Central Compartment Involvement in Patients with Positive Lateral Cervical Lymph Nodes According to Clinical and/or Ultrasound Evaluation

Author

Graceffa, Giuseppa, primary, Orlando, Giuseppina, additional, Cocorullo, Gianfranco, additional, Mazzola, Sergio, additional, Vitale, Irene, additional, Proclamà, Maria Pia, additional, Amato, Calogera, additional, Saputo, Federica, additional, Rollo, Enza Maria, additional, Corigliano, Alessandro, additional, Melfa, Giuseppina, additional, Cipolla, Calogero, additional, and Scerrino, Gregorio, additional

Published
2021
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8. Improving Diagnostic Performance for Thyroid Nodules Classified as Bethesda Category III or IV: How and by Whom Ultrasonography Should be Performed

Author

Scerrino, Gregorio, primary, Cocorullo, Gianfranco, additional, Mazzola, Sergio, additional, Melfa, Giuseppina, additional, Orlando, Giuseppina, additional, Laise, Iole, additional, Corigliano, Alessandro, additional, Lo Brutto, Daniela, additional, Cipolla, Calogero, additional, and Graceffa, Giuseppa, additional

Published
2021
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9. Autologous peripheral blood mononuclear cells for the treatment of lower extremity lymphedema: A preliminary report.

Author

Bellisi, Mario, Guttuso, Ilenia, Murabito, Alessandra, Corigliano, Alessandro, Filice, Rossella, Trovato, Christian, and Costa, Renato Patrizio

Subjects
MONONUCLEAR leukocytes, LYMPHEDEMA
Abstract

Lymphedema is a chronic devastating disease characterized by the accumulation of fluid in the extremities, tissue progressive changes such as adipose tissue deposition and fibrosis. To restore the functionality and structural integrity of the damaged lymphatic vessels, autologous peripheral blood mononuclear cells (PBMNC) was implanted in 3 sessions, 4 weeks apart, in the affected limb. Each patient was followed for 6 months, monitoring changes in the limb volume. Lymphangiogenesis was evaluated by lymphoscintigraphy, and the monitoring of quality of life. A rapid reduction in the volume of the limbs was observed: Twenty-four point 5 percent of volume reduction after the first implant, 18.5% after the second, and 15.3% at 6 months after the third (p<0.05 vs baseline). Lymphoscintigraphy showed a hyper fixation of the tracer along the ipsilateral iliac axis not appreciable at baseline. Implants of autologous PBMNC in patients with primary lower limb lymphedema seems to be a feasible, effective therapy option. [ABSTRACT FROM AUTHOR]

Published
2021
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10. Predictors of Central Compartment Involvement in Patients with Positive Lateral Cervical Lymph Nodes According to Clinical and/or Ultrasound Evaluation

Author

Enza Maria Rollo, Federica Saputo, Calogera Amato, Giuseppa Graceffa, Maria Pia Proclamà, Giuseppina Orlando, Alessandro Corigliano, G. Melfa, Gregorio Scerrino, Gianfranco Cocorullo, Calogero Cipolla, S Mazzola, Irene Vitale, Graceffa, Giuseppa, Orlando, Giuseppina, Cocorullo, Gianfranco, Mazzola, Sergio, Vitale, Irene, Proclamà, Maria Pia, Amato, Calogera, Saputo, Federica, Rollo, Enza Maria, Corigliano, Alessandro, Melfa, Giuseppina, Cipolla, Calogero, and Scerrino, Gregorio

Subjects
medicine.medical_specialty, skip metastasis, endocrine system diseases, medicine.medical_treatment, 030230 surgery, Article, 03 medical and health sciences, 0302 clinical medicine, central compartment, medicine, lateralcervical lymph nodes, Lymph node, Univariate analysis, business.industry, EU-TIRADS, Bethesda, Cancer, Neck dissection, General Medicine, medicine.disease, Central lymph, Dissection, medicine.anatomical_structure, lateral neck dissection, 030220 oncology & carcinogenesis, central neck dissection, papillary thyroid carcinoma, Medicine, Radiology, Lymph, Thyroid function, business
Abstract

Lymph node neck metastases are frequent in papillary thyroid carcinoma (PTC). Current guidelines state, on a weak level of evidence, that level VI dissection is mandatory in the presence of latero-cervical metastases. The aim of our study is to evaluate predictive factors for the absence of level VI involvement despite the presence of metastases to the lateral cervical stations in PTC. Eighty-eight patients operated for PTC with level II–V metastases were retrospectively enrolled in the study. Demographics, thyroid function, autoimmunity, nodule size and site, cancer variant, multifocality, Bethesda and EU-TIRADS, number of central and lateral lymph nodes removed, number of positive lymph nodes and outcome were recorded. At univariate analysis, PTC location and number of positive lateral lymph nodes were risk criteria for failure to cure. ROC curves demonstrated the association of the number of positive lateral lymph nodes and failure to cure. On multivariate analysis, the protective factors were PTC located in lobe center and number of positive lateral lymph nodes &lt, 4. Kaplan–Meier curves confirmed the absence of central lymph nodes as a positive prognostic factor. In the selected cases, Central Neck Dissection (CND) could be avoided even in the presence of positive Lateralcervical Lymph Nodes (LLN+).

Published
2021

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