13 results on '"Coretti F"'
Search Results
2. Left-ventricular non-compaction and ventricular arrhythmias
- Author
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Principi, S, primary, Alfieri, M, additional, Barbarossa, A, additional, Ciliberti, G, additional, Coretti, F, additional, Coraducci, F, additional, Belleggia, S, additional, Torselletti, L, additional, Paolini, F, additional, Stronati, G, additional, Dello Russo, A, additional, and Guerra, F, additional
- Published
- 2023
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3. P205 COMPASSIONATE DRUG USE FOR PATIENTS WITH TRANSTHYRETIN AMYLOID CARDIOMYOPATHY: THE FIRST EXPERIENCE IN ITALY
- Author
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Ciliberti, G, primary, Torselletti, L, additional, Barbarossa, A, additional, Principi, S, additional, Coraducci, F, additional, Belleggia, S, additional, Coretti, F, additional, Bonci, A, additional, Stronati, G, additional, Casella, M, additional, Dello Russo, A, additional, and Guerra, F, additional
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- 2023
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4. Long-term prognosis in left ventricular non-compaction cardiomyopathy
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Guerra, F, primary, Barbarossa, A, additional, Alfieri, M, additional, Paolini, F, additional, Stronati, G, additional, Ciliberti, G, additional, Torselletti, L, additional, Coretti, F, additional, Coraducci, F, additional, Belleggia, S, additional, Principi, S, additional, Silenzi, M, additional, Manfredi, R, additional, Falanga, U, additional, and Dello Russo, A, additional
- Published
- 2022
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5. Prognostic role of low QRS voltages in patients with cardiac amyloidosis
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Guerra, F, primary, Coretti, F, additional, Torselletti, L, additional, Coraducci, F, additional, Belleggia, S, additional, Manfredi, R, additional, Silenzi, M, additional, Falanga, U, additional, Principi, S, additional, Stronati, G, additional, Ciliberti, G, additional, Barbarossa, A, additional, Casella, M, additional, and Dello Russo, A, additional
- Published
- 2022
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6. Predictive value of basal antral follicle count in controlled ovarian hyperstimulation for assisted reproductive technologies: 202
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Cobuzzi, I., Vacca, M., Capuano, P., Cantatore, C., Nocera, S., Coretti, F., Falagario, D., Garruti, G., and Depalo, R.
- Published
- 2011
7. Serial cardiac magnetic resonance imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis.
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Bianco F, Bucciarelli V, Coretti F, Cataldi S, Damadei F, Raffaelli E, Schicchi N, Omenetti A, Lattanzi B, Berton E, Chiara Surace F, Baldinelli A, Breda L, Cazzato S, Catassi C, Dello Russo A, and Gallina S
- Abstract
Aims: To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with C-reactive protein (CRP) assay alone., Methods and Results: In 2018-21, we enrolled 18 (14.5 ± 1.8 years old, 72% males) consecutive RP patients treated with anakinra (100 mg/day in patients ≥ 18 years old; 2 mg/kg/day < 18 years old) due to RP corticosteroid-dependent or not responsive to colchicine or non-steroidal anti-inflammatory drugs. After hospitalization, they were 1:1 randomized to CMR [no pericardial oedema and/or late gadolinium enchantment (LGE)] or CRP (<0.6 mg/dL). Tests were repeated every 3 months until negative to halve the anakinra dosage and cessation. The idiopathic aetiology was the most prevalent ( n = 8, 44%), followed by post-pericardiotomy ( n = 6, 33%). After a median treatment period of 8.7 ± 3.6 months, CRP-guided RP patients experienced more recurrences than CMR-guided ones (6 vs. 1, P = 0.016), with the worst prognosis in terms of recurrences (log-rank, P = 0.025) and significantly increased time of treatment (12.7 ± 2 vs. 16.1 ± 3.4 months, P = 0.019). In a multivariable exploratory Cox regression model, the number of previous recurrences and the idiopathic aetiology were independent predictors of RP during the anakinra treatment. New recurrences were subsequently directed to CMR imaging, and therapy was modified according to the LGE/oedema trend. After 1-year follow-up, no further recurrence was detected., Conclusion: Among patients with RP and treated with anakinra, serial CMR imaging of the pericardium can be utilized as an imaging biomarker, more informative for therapy duration than the solely CRP assessment., Clinicaltrialsgov Identifier: NCT06071156., Competing Interests: Conflict of interest: None declared., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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- 2024
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8. Giant aneurysm of the left atrial appendage: a case report.
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Coraducci F, Barbarossa A, Coretti F, Belleggia S, and Guerra F
- Abstract
Background: Left atrial appendage aneurysm (LAAA) is a rare condition mostly due to congenital malformations or secondary causes (i.e. mitral regurgitation)., Case Summary: We present a case of a 47-year-old male with a history of atrial fibrillation treated with propafenone presented to our emergency department for palpitation and epigastric pain. The electrocardiogram showed atrial fibrillation at high ventricular rate and a new-onset left bundle branch block. Urgent coronary angiogram excluded coronary artery disease. Echocardiography and cardiac magnetic resonance revealed a giant LAAA. The electrocardiogram alterations were deemed secondary to aberrancy and treatment with class IC antiarrhythmic. The patient was discussed in the heart team, and considering his will to avoid surgery, he was managed conservatively with closed follow-up, anticoagulant and antiarrhythmic therapy, and internal loop recorder. At 1-year follow-up, he showed asymptomatic and without arrhythmias., Discussion: Few cases are described in the literature; therefore, there is uncertainty in treatment and prognosis. Diagnosis is achieved with multimodality imaging. Treatment can be surgical with aneurysmectomy or conservative with regular follow-up by imaging examinations and pharmacological therapy aimed to prevent complications such as thrombosis and arrhythmias. Since high-quality scientific data are lacking, shared decision-making is essential for the management of patients affected by LAAA. In our clinical case, our patient's will to not undergo surgery was considered, and therefore, a conservative management with strict follow-up and medications was chosen., Competing Interests: Conflict of interest: None declared., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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- 2024
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9. Evaluating adherence, tolerability and safety of oral calcium citrate in elderly osteopenic subjects: a real-life non-interventional, prospective, multicenter study.
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Rondanelli M, Minisola S, Barale M, Barbaro D, Mansueto F, Battaglia S, Bonaccorsi G, Caliri S, Cavioni A, Colangelo L, Corbetta S, Coretti F, Dito G, Gavioli V, Ghigo E, Giannattasio R, Lapi P, Maiorana B, Marra C, Mazzantini M, Morini E, Nannipieri F, Nuzzo V, Parri F, Perna S, Santori R, and Procopio M
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- Humans, Female, Aged, Male, Calcium, Prospective Studies, Calcium, Dietary, Dietary Supplements adverse effects, Calcium Citrate adverse effects, Osteoporosis drug therapy
- Abstract
Background: Osteoporosis is a common concern in the elderly that leads to fragile bones. Calcium supplementation plays a crucial role in improving bone health, reducing fracture risk, and supporting overall skeletal strength in this vulnerable population. However, there is conflicting evidence on the safety of calcium supplements in elderly individuals., Aim: The aim of this study was to evaluate the adherence, safety and tolerability of calcium citrate supplementation in elderly osteopenic subjects., Methods: In this non-interventional, prospective, multicenter study, subjects received daily 500 mg calcium citrate supplementation for up to one year. Adherence was calculated based on compliance and persistence. Safety was assessed through adverse reactions (ARs), deaths, and clinical laboratory evaluations., Results: A total of 268 Caucasian subjects (91.4% female, mean age 70 ± 4.5 years) participated in the study. Mean adherence to treatment was 76.6 ± 29.5% and half of subjects had an adherence of 91% and ~ 33% of participants achieved complete (100%) adherence. ARs were reported by nine (3.9%) subjects, primarily gastrointestinal disorders, with no serious ARs. The frequency of all adverse events (including ARs) was significantly higher in subjects with adherence of < 80% (41.6%; 32/77) vs. those with adherence ≥ 80% (11%; 16/145, p < 0.0001). Both systolic and diastolic blood pressure decreased from baseline to follow-up visit (change of -2.8 ± 13.9 mmHg, p = 0.0102 and -2.1 ± 10.4 mmHg, p = 0.0116, respectively)., Conclusion: This study demonstrated favorable adherence to calcium citrate supplementation in elderly osteopenic subjects. The occurrence of ARs, though generally mild, were associated with lower adherence to calcium supplementation., (© 2024. The Author(s).)
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- 2024
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10. Calcium daily intake and the efficacy of a training intervention on optimizing calcium supplementation therapy: A clinical audit.
- Author
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Muscariello R, Rendina D, Giannettino R, Ippolito S, Romano O, Coretti F, De Vita S, Martino M, Sepe C, and Nuzzo V
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- Adult, Aged, Calcium deficiency, Diet, Healthy, Drug Prescriptions, Drug Utilization, Feeding Behavior, Female, Humans, Italy, Male, Medical Audit, Middle Aged, Recommended Dietary Allowances, Calcium administration & dosage, Calcium, Dietary administration & dosage, Dietary Supplements, Education, Medical, Continuing, General Practitioners education, Health Knowledge, Attitudes, Practice, Practice Patterns, Physicians'
- Abstract
Background and Aims: Calcium is an essential element for human health, with key roles in the prevention and therapy of multifactorial conditions. Calcium dietary intake is often insufficient in the general population. The aim of this study was to perform a clinical audit for general practitioners (GPs) to understand the efficacy of training intervention on doctors' awareness about dietary calcium and supplements., Methods and Results: General practice outpatients were enrolled (Before Clinical Audit, BCA) from the same sanitary district, and calcium dietary intake was evaluated with a validated questionnaire, also collecting information about the consumption of calcium and vitamin D supplements. Then, a training intervention with a frontal lesson and discussion with GPs involved was performed. After one month of this intervention, a second outpatient enrolment was performed (Post Clinical Audit, PCA) in the same general practices to evaluate differences in nutritional suggestions and supplement prescription by GPs. In BCA, the calcium dietary intake was low, with nobody reaching 1000 mg as suggested by the guidelines. Only 6.6% and 24.5% took calcium and vitamin D supplements, respectively; in the PCA, these percentages increased to 28% and 78% for calcium and vitamin D supplements, respectively (p < 0.01 PCA vs BCA). There were no differences in calcium dietary intake between BCA and PCA., Conclusion: Training intervention on GPs was successful to sensitize them regarding calcium intake problems; GPs tended to increase the prescription of supplements but not to suggest changes in dietary habits., Competing Interests: Declaration of competing interest No one of the Authors have conflicts of interest., (Copyright © 2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.)
- Published
- 2021
- Full Text
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11. A clinical audit: diagnostic and epidemiological evaluation of the adrenal incidentaloma.
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Nuzzo V, Attardo T, Augello G, Brancato D, Canale C, Camerlingo S, Coretti F, Franco A, Giacometti F, Gambacorta M, Loreno M, Maffettone A, Provenzano V, and Zuccoli A
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- Adrenal Cortex Hormones blood, Adrenal Gland Neoplasms diagnostic imaging, Adrenalectomy, Clinical Audit, Diagnosis, Differential, Humans, Incidence, Incidental Findings, Italy epidemiology, Magnetic Resonance Imaging, Tomography, X-Ray Computed, Adrenal Gland Neoplasms diagnosis, Adrenal Gland Neoplasms epidemiology
- Abstract
Background: Audit is a clinical instrument of government characterized by a whole process of evaluation inter pares to improve medical behaviors in the clinical practice. Different endocrinopathies are underestimated in the clinical and diagnostics practice but they can be a real problem in patients admitted in the departments of Internal Medicine. The adrenal incidentaloma is an accidental discovery with an incidence equal to 4% in radiologic studies but it's rarely considereted in the internal disorders. In the departments of Internal Medicine are hospitalized each year approximately 1450,000 patients and 58,000 about them show a surrenalic lesion identified with CT or MRI as Adrenal Incidentaloma., Methods: Through a search in the radiological archives, were reviewed all abdominal CT performed in the year 2012 in 8 departments of Internal Medicine of 8 Italian public hospitals. They also examined all medical records of these patients to value clinical management of the adrenal masses and the real incidence of the adrenal incidentaloma., Results: Distribution of pathological results show an important incidence about adrenal incidentaloma in Italian patients although this pathology is represented as a rare disease and its clinical and economic burden are significant. Many questions remain unanswered as the association between duration and severity of the disease, morbidity and how the dimensions affecting it. These results need to be supported by important studies with long follow-up to realize an easy diagnosis., Conclusions: The results of this audit confirm the real incidence of this pathology in the internistic patients and the final target is to implement changes about therapeutic diagnostic pathway of the hospital patients in the internal medicine departments.
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- 2020
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12. Shorter telomeres in patients with cerebral autosomal dominant arteriopathy and leukoencephalopathy (CADASIL).
- Author
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Ragno M, Pianese L, Pinelli M, Silvestri S, Cacchiò G, Di Marzio F, Scarcella M, Coretti F, Altamura F, Monticelli A, and Castaldo I
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- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, CADASIL genetics, Telomere metabolism, Telomere Shortening
- Abstract
CADASIL is a hereditary systemic vasculopathy which affects mainly small cerebral arteries and is caused by mutations in the Notch3 gene. Misfolding of Notch3 is linked to endoplasmic reticulum stress and increased reactive oxygen species, which may result in dysfunction of endothelial cells, inflammation and ischemia. Oxidative stress and inflammation may induce a rapid telomere shortening in peripheral blood leukocytes (PBLs). The aim of this study was to assess the telomere length in PBLs from 29 patients with a genetic diagnosis of CADASIL by using a modified quantitative real-time polymerase chain reaction based assay. PBL telomere length was significantly shorter in CADASIL patients (T/S ratio = 0.17, 95% CI, 0.14-0.20) than in the controls (T/S ratio = 0.31, 95% CI, 0.27-0.35, t-test p < 0.001). Moreover, patients with functional dependence displayed shorter telomeres than those with functional independence (p = 0.039). Our data provide the first evidence that PBL telomere length is shortened in CADASIL disease, and this may be a systemic oxidative stress indicator in CADASIL patients, providing a possible biomarker of disease progression and for future therapeutic strategies.
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- 2011
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13. Semen quality and hormonal levels in infertile patients with varicocele.
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Cantatore C, Capuano P, Cobuzzi I, Vacca M, Coretti F, Falagario D, Spilotros M, Bettocchi C, Palumbo F, and Depalo R
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- Adult, Follicle Stimulating Hormone blood, Humans, Infertility, Male blood, Male, Retrospective Studies, Testosterone blood, Infertility, Male etiology, Semen Analysis, Varicocele complications
- Abstract
Objective: Aim of this study was to evaluate the semen quality and the serum concentration of follicle-stimulating hormone (FSH) and Testosterone (T) in infertile patients with and without varicocele., Material and Methods: 365 infertile patients undergoing Assisted Reproduction Tecnique (ART) were retrospectively included in the study. All subject were evaluated by history, physical examination, semen analysis, semen culture, mixed anti-immunoglobulin reaction test (MAR) for demonstration of sperm agglutination antibodies IgG and IgA, serum FSH and T determination., Results: We observed 97 (26.6%) patients affected by varicocele compared to 268 (73.4%) without varicocele. A significant reduced percentage of motile spermatozoa (24.58 +/- 21.68 vs 21.01 +/- 12.62, p < 0.001) and lower sperm concentration (15.50 +/- 23.30 vs 16.50 +/- 15.22, p < 0.001) were observed in patients with varicocele compared to patients without varicocele. No significant differences were observed in sperm vitality between the two population of men with and without varicocele. Serum FSH (10.42 +/- 10.84 vs 9.11 +/- 18.81, p < 0.001) and Testosterone (5.73 +/- 5.97 vs 5.21 +/- 2.43, p < 0.001) levels were significantly higher in patients with varicocele compared to patients without varicocele. Detection of IgG and IgA sperm antibodies were negative in both man with and without varicocele., Conclusion: The direct connection between varicocele and infertility is not clear. The data of the present study suggest that the presence of a clinical varicocele rule out fertility in men affecting the hypothalamic pituitary-gonadal axis.
- Published
- 2010
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