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2 results on '"Cordero CN"'

1. Efficacy of a 1-week, once-daily regimen of terbinafine 1% cream in the treatment of tinea cruris and tinea corporis.

Author

Zaias N, Berman B, Cordero CN, Hernandez A, Jacobson C, Millikan L, Rojas R, de la Rosa I, Villars V, and Birnbaum JE

Subjects
Administration, Cutaneous, Antifungal Agents therapeutic use, Double-Blind Method, Drug Administration Schedule, Follow-Up Studies, Humans, Naphthalenes therapeutic use, Ointments, Terbinafine, Tinea drug therapy, Treatment Outcome, Antifungal Agents administration & dosage, Naphthalenes administration & dosage, Tinea Capitis drug therapy
Published
1993
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2. Naftifine cream in the treatment of cutaneous candidiasis.

Author

Zaias N, Astorga E, Cordero CN, Day RM, de Espinoza ZD, DeGryse R, Rojas RF, and Sefton J

Subjects
Adolescent, Adult, Aged, Allylamine adverse effects, Allylamine analogs & derivatives, Allylamine therapeutic use, Antifungal Agents adverse effects, Antifungal Agents therapeutic use, Clinical Trials as Topic, Double-Blind Method, Female, Humans, Male, Middle Aged, Ointments, Allylamine administration & dosage, Amines administration & dosage, Antifungal Agents administration & dosage, Candidiasis, Cutaneous drug therapy
Abstract

Naftifine, a member of a new class of synthetic antifungal drugs, the allylamines, was evaluated for the treatment of cutaneous candidiasis. In a double-blind, parallel-group clinical trial, sixty patients with cutaneous candidiasis were randomly assigned to receive either naftifine cream 1 percent or its vehicle twice a day for three weeks. Two weeks after the end of therapy, 77 percent of the naftifine-treated patients were mycologically cured (negative results on potassium hydroxide preparations and culture) and had no clinically apparent disease, compared with 3 percent of the patients treated with vehicle (p less than 0.001). Side effects reported with naftifine cream were few and minor.

Published
1988

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