1. Analysis during chest compressions in out-of-hospital cardiac arrest patients, a cross/sectional study: The DEFI 2022 study.
- Author
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Derkenne C, Frattini B, Menetre S, Hong Tuan Ha V, Lemoine F, Beganton F, Didon JP, Rozenberg E, Salome M, Trichereau J, Corcostegui SP, Lemoine S, Kedzierewicz R, Burlaton G, Vial V, Dessertaine T, Miron De L'Espinay A, Jouven X, Travers S, and Jost D
- Subjects
- Humans, Cross-Sectional Studies, Male, Female, Middle Aged, Aged, Heart Massage methods, Defibrillators statistics & numerical data, Electric Countershock methods, Electric Countershock statistics & numerical data, Ventricular Fibrillation therapy, Ventricular Fibrillation complications, Time Factors, Emergency Medical Services methods, Emergency Medical Services statistics & numerical data, Algorithms, Out-of-Hospital Cardiac Arrest therapy, Out-of-Hospital Cardiac Arrest mortality, Cardiopulmonary Resuscitation methods, Cardiopulmonary Resuscitation statistics & numerical data
- Abstract
Aims: During out-of-hospital cardiac arrest (OHCA), an automatic external defibrillator (AED) analyzes the cardiac rhythm every two minutes; however, 80% of refibrillations occur within the first minute post-shock. We have implemented an algorithm for Analyzing cardiac rhythm While performing chest Compression (AWC). When AWC detects a shockable rhythm, it shortens the time between analyses to one minute. We investigated the effect of AWC on cardiopulmonary resuscitation quality., Method: In this cross-sectional study, we compared patients treated in 2022 with AWC, to a historical cohort from 2017. Inclusion criteria were OHCA patients with a shockable rhythm at the first analysis. Primary endpoint was the chest compression fraction (CCF). Secondary endpoints were cardiac rhythm evolution and survival, including survival analysis of non-prespecified subgroups., Results: In 2017 and 2022, 355 and 377 OHCAs met the inclusion criteria, from which we analyzed the 285 first consecutive cases in each cohort. CCF increased in 2022 compared to 2017 (77% [72-80] vs 72% [67-76]; P < 0.001) and VF recurrences were shocked more promptly (53 s [32-69] vs 117 s [90-132]). Survival did not differ between 2017 and 2022 (adjusted hazard-ratio 0.96 [95% CI, 0.78-1.18]), but was higher in 2022 within the sub-group of OHCAs that occurred in a public place and within a short time from call to AED switch-on (adjusted hazard ratio 0.85[0.76-0.96])., Conclusions: OHCA patients treated with AWC had higher CCF, shorter time spent in ventricular fibrillation, but no survival difference, except for OHCA that occurred in public places with short intervention time., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: “Sarah Menetre reports a relationship with Schiller Medical France that includes: employment. Jean-Philippe Didon reports a relationship with Schiller Medical France that includes: employment. Xavier Jouven reports a relationship with Schiller Medical France that includes: funding grants. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.”, (Copyright © 2024. Published by Elsevier B.V.)
- Published
- 2024
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