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8. Micellar crowding and branching in a versatile catanionic system

Author

Asaro, Fioretta, Coppola, Luigi, and Gentile, Luigi

Subjects
Condensed Matter - Soft Condensed Matter
Abstract

The catanionic system didodecyldimethylammonium bromide (DDAB)- sodium taurodeoxycholate (STDC)-D2O is characterized by an exceptionally extended L1 region. The comparison of self-diffusion coefficient of the solvent and the DDAB embedded in the micelles provided information about hydration of the aggregates. Moreover, correlating self-diffusion and 14N NMR relaxation measurements new insight could be obtained regarding the translational and rotational micellar motions in the crowded solutions of systems with 0.2 DDABSTDC molar ratio. 1H 2D NMR spectra gave some hints about the mutual arrangement of DDAB and STDC within the aggregates. For samples with 1.8 and 2.6 DDAB/STD molar ratios the 14N data were in agreement with the presence of somewhat branched, interconnected micelles. 23Na and 81Br dynamic parameters resulted particularly sensitive to the surrounding environment. The peculiar rheological behaviour of the, highly concentrated, branched micelles samples, namely the steady oscillations in the step tests, was found to be an example of instability originated by the combined effect of material elasticity and slippage at the fixed wall.

Published
2022
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15. Immunogenicity and reactogenicity of modified vaccinia Ankara pre-exposure vaccination against mpox according to previous smallpox vaccine exposure and HIV infection: prospective cohort study

Author

Anzalone, Enza, Camici, Marta, Cannone, Fabio, Caputi, Priscilla, Cimaglia, Claudia, Corso, Rita, Cristofanelli, Flavia, Cruciani, Stefania, De Marco, Nicola, De Ponte, Chiara, Del Duca, Giulia, Faccendini, Paolo, Faraglia, Francesca, Faticoni, Augusto, Fusto, Marisa, Gebremeskel, Saba, Giancola, Maria Letizia, Giannico, Giuseppina, Gili, Simona, Iannella, Maria Rosaria, Junea, Angela, Lamonaca, Alessandra, Marani, Alessandra, Masone, Erminia, Mastrorosa, Ilaria, Mazzotta, Stefania, Nappo, Alessandra, Natalini, Giorgia, Parisi, Alfredo, Passacantilli, Sara, Paulicelli, Jessica, Plazzi, Maria Maddalena, Possi, Adriano, Preziosi, Gianni, Rosati, Silvia, Rubino, Marika, Scanzano, Pietro, Scorzolini, Laura, Tomassi, Virginia, Vescovo, Maurizio, Vita, Serena, Caterini, Luciano, Coppola, Luigi, Kontogiannis, Dimitra, D'Ettorre, Gabriella, Ridolfi, Marco, Di Giambenedetto, Simona, Farinacci, Damiano, Latini, Alessandra, Marchili, Mauro, Marocco, Raffaella, Mazzotta, Valentina, Lepri, Alessandro Cozzi, Matusali, Giulia, Cimini, Eleonora, Piselli, Pierluca, Aguglia, Camilla, Lanini, Simone, Colavita, Francesca, Notari, Stefania, Oliva, Alessandra, Meschi, Silvia, Casetti, Rita, Mondillo, Vanessa, Vergori, Alessandra, Bettini, Aurora, Grassi, Germana, Pinnetti, Carmela, Lapa, Daniele, Tartaglia, Eleonora, Gallì, Paola, Mondi, Annalisa, Montagnari, Giulia, Gagliardini, Roberta, Nicastri, Emanuele, Lichtner, Miriam, Sarmati, Loredana, Tamburrini, Enrica, Mastroianni, Claudio, Stingone, Christof, Siddu, Andrea, Barca, Alessandra, Fontana, Carla, Agrati, Chiara, Girardi, Enrico, Vaia, Francesco, Maggi, Fabrizio, and Antinori, Andrea

Published
2024
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16. Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves

Author

Fanelli, Marialaura, Petrone, Vita, Maracchioni, Christian, Chirico, Rossella, Cipriani, Chiara, Coppola, Luigi, Malagnino, Vincenzo, Teti, Elisabetta, Sorace, Chiara, Zordan, Marta, Vitale, Pietro, Iannetta, Marco, Balestrieri, Emanuela, Rasi, Guido, Grelli, Sandro, Malergue, Fabrice, Sarmati, Loredana, Minutolo, Antonella, and Matteucci, Claudia

Published
2024
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18. Thymosin alpha 1 restores the immune homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection

Author

Minutolo, Antonella, Petrone, Vita, Fanelli, Marialaura, Maracchioni, Christian, Giudice, Martina, Teti, Elisabetta, Coppola, Luigi, Sorace, Chiara, Iannetta, Marco, Tony Miele, Martino, Bernardini, Sergio, Mastino, Antonio, Sinibaldi Vallebona, Paola, Balestrieri, Emanuela, Andreoni, Massimo, Sarmati, Loredana, Grelli, Sandro, Garaci, Enrico, and Matteucci, Claudia

Published
2023
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19. Renal alterations in cats (Felis catus) housed in shelters and affected by systemic AA-amyloidosis: Clinicopathological data, histopathology, and ultrastructural features

Author

Ferri, Filippo, primary, Ferro, Silvia, additional, Lucia Benali, Silvia, additional, Aresu, Luca, additional, Muscardin, Lorenza, additional, Porporato, Federico, additional, Rossi, Francesco, additional, Guglielmetti, Chiara, additional, Gallo, Enrico, additional, Palizzotto, Carlo, additional, Callegari, Carolina, additional, Ricagno, Stefano, additional, Mazza, Maria, additional, Michele Coppola, Luigi, additional, Gerardi, Gabriele, additional, Lavatelli, Francesca, additional, Caminito, Serena, additional, Mazzini, Giulia, additional, Palladini, Giovanni, additional, Merlini, Giampaolo, additional, and Zini, Eric, additional

Published
2024
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20. Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease

Author

Marizzoni, Moira, primary, Cattaneo, Annamaria, additional, Mirabelli, Peppino, additional, Festari, Cristina, additional, Lopizzo, Nicola, additional, Nicolosi, Valentina, additional, Mombelli, Elisa, additional, Mazzelli, Monica, additional, Luongo, Delia, additional, Naviglio, Daniele, additional, Coppola, Luigi, additional, Salvatore, Marco, additional, and Frisoni, Giovanni B., additional

Published
2022
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22. Alkali-Activated Slag as Sustainable Binder for Pervious Concrete and Structural Plaster: A Feasibility Study.

Author

Coffetti, Denny, Rapelli, Simone, and Coppola, Luigi

Subjects
MINERAL aggregates, CONSTRUCTION materials, BINDING agents, SUSTAINABLE construction, RETROFITTING of buildings
Abstract

In the realm of sustainable construction materials, the quest for low-environmental-impact binders has gained momentum. Addressing the global demand for concrete, several alternatives have been proposed to mitigate the carbon footprint associated with traditional Portland cement production. Despite technological advancements, property inconsistencies and cost considerations, the wholesale replacement of Portland cement remains a challenge. This study investigates the feasibility of using alkali-activated slag (AAS)-based binders for two specific applications: structural plaster and pervious concrete. The research aims to develop an M10-grade AAS plaster with a 28-day compressive strength of at least 10 MPa for the retrofitting of masonry buildings. The plaster achieved suitable levels of workability and applicability by trowel as well as a 28-day compressive strength of 10.8 MPa, and the level shrinkage was reduced by up to 45% through the inclusion of shrinkage-reducing admixtures. Additionally, this study explores the use of tunnel muck as a recycled aggregate in AAS pervious concrete, achieving a compressive strength up to 20 MPa and a permeability rate from 500 to 3000 mm/min. The relationship between aggregate size and the physical and mechanical properties of no-fines concretes usually used for cement-based pervious concrete was also confirmed. Furthermore, the environmental impacts of these materials, including their global warming potential (GWP) and gross energy requirement (GER), are compared to those of conventional mortars and concretes. The findings highlight that AAS materials reduce the GWP from 50 to 75% and the GER by about 10–30% compared to their traditional counterparts. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Histoplasmosis in patients living with HIV in Europe: review of literature.

Author

Kontogiannis, Dimitra, Di Lorenzo, Andrea, Zaçe, Drieda, Benvenuto, Domenico, Moccione, Martina, Muratore, Gianmarco, Giacalone, Maria L., Montagnari, Giulia, Carnevale, Laura, Mulas, Tiziana, Coppola, Luigi, Campogiani, Laura, Sarmati, Loredana, and Iannetta, Marco

Subjects
LITERATURE reviews, HISTOPLASMOSIS, EUROPEAN literature, HIV-positive persons, OPPORTUNISTIC infections, ITRACONAZOLE, ARACHNOID cysts
Abstract

Histoplasma capsulatum (var. capsulatum Hcc and duboisii Hcd), is a dimorphic fungus that causes histoplasmosis. It usually affects people coming from endemic areas, causing a variety of clinical manifestations up to progressive disseminated histoplasmosis (PDH), especially among people living with HIV (PLWH). We conducted a systematic review to assess histoplasmosis burden of PLWH in Europe. The review follows PRISMA guidelines, with protocol registered in PROSPERO (CRD42023429779). Seventy-eight articles were selected, including 109 patients (32 women). On overall, median age was 37  years. Forty-six patients were Americans, 39 Africans, 17 Europeans, 5 Asians, in 2 cases nationality was not specified. Cases were mainly diagnosed in Italy (28.4%), France (17.3%) and Spain (17.4%), with a north–south gradient. Six cases lacked epidemiologic links with endemic areas. Concerning CDC HIV staging at diagnosis, the information was available for 60 PLWH (55%) and all subjects were at stage C3 except for two subjects at stage B3. PDH was the AIDS-presenting illness in 39 patients. Most patients had a PDH (80.7%); other common extrapulmonary forms were isolated cutaneous histoplasmosis (7.3%), or lymphatic localization (2.7%). In 30 cases, the diagnosis was made by analyzing only one sample. For the remaining 79 cases, multiple samples were collected from each patient. Regarding the biological sample more frequently used for the diagnosis of histoplasmosis, bronchoalveolar lavage sample was taken from 39 patients, and tested positive in 51.3% of cases; 36 patients underwent a skin biopsy which was positive in 86.1% of cases and 28 patients performed bone-marrow biopsy, which led to the diagnosis of histoplasmosis in 92.9% of cases. The identification of Histoplasma capsulatum was available in 97 PLWH through examination of different samples: Hcc and Hcd were identified in 89 and 8 PLWH, respectively. Concerning therapies, 67.9% were treated with liposomal amphotericin B, 18.3% with itraconazole, 10 died pre-treatment. The overall mortality rate was 23.6%. Non-survivors exhibited more frequently gastrointestinal symptoms (p  =  0.017), while cutaneous signs correlated with better survival (p  =  0.05). Untreated patients faced higher mortality (p  <  0.001). Histoplasmosis should be considered amongst opportunistic infection in PLWH, even in Europe, especially if patients originate from or have travelled to endemic areas. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Decision-Making BIM Platform for Chemical Building Products

Author

Gazzaniga, Gabriele, Coppola, Luigi, Daniotti, Bruno, Mirachi, Claudio, Pavan, Alberto, Savoia, Valeria, Bartezzaghi, Emilio, Series Editor, Bracchi, Giampio, Series Editor, Del Bo, Adalberto, Series Editor, Sagarra Trias, Ferran, Series Editor, Stellacci, Francesco, Series Editor, Zio, Enrico, Series Editor, Daniotti, Bruno, editor, Gianinetto, Marco, editor, and Della Torre, Stefano, editor

Published
2020
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27. Corrosion in Concrete: Inhibitors and Coatings.

Author

Coppola, Luigi and Coppola, Luigi

Subjects
History of engineering & technology, Technology: general issues, 3D scanning, EDS, EIS, HDG, LPR, SEM, acid spraying test, adhesive strength, bond strength, cathodic protection, chloride ion corrosion resistance, chloride penetration, chlorides, coatings, compressive strength, concrete, concrete bio-corrosion, corrosion, corrosion inhibitor, durability, durability of concrete, electrochemical noise, fly ash, geopolymer coatings (GPC), impermeability, magnesium hydroxide coating, microstructure, n/a, optical measurements, pullout, rebar corrosion, reinforcing steel, setting time, sewerage pipe systems, silane-based surface treatment, steel fiber reinforced concrete, sulfuric acid corrosion control, zinc coating, zinc phosphate
Abstract

Summary: Improving the durability of reinforced concrete structures is a mandatory strategy to reduce the environmental impact of construction materials together with aiming to limit carbon dioxide emissions, energy consumption and natural raw materials depletion. Hence, for both new and existing concrete structures, proper protective techniques are required to prevent premature failure induced by environmental aggressive agents. The book presents the most innovative findings both in designing durable new constructions and toward solving durability deficiencies in existing concrete structures, such as innovative special coatings, hydrophobic impregnations and pore blocking treatments that are very efficient in severe aggressive environments (seawater, biocorrosion, etc.). Moreover, migrant corrosion inhibitors applied on concrete surfaces are able to greatly improve resistance against both chloride and CO2. Finally, special reinforcements and fibers, together with a proper designed cathodic protection, can greatly contribute to obtaining long-life reinforced concrete structures, significantly increasing the sustainability of concrete construction.

36. Classifying breast cancer and fibroadenoma tissue biopsies from paraffined stain-free slides by fractal biomarkers in Fourier Ptychographic Microscopy

Author

Bianco, Vittorio, primary, Valentino, Marika, additional, Pirone, Daniele, additional, Miccio, Lisa, additional, Memmolo, Pasquale, additional, Brancato, Valentina, additional, Coppola, Luigi, additional, Smaldone, Giovanni, additional, D'Aiuto, Massimiliano, additional, Mossetti, Gennaro, additional, Salvatore, Marco, additional, and Ferraro, Pietro, additional

Published
2023
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38. Primary Anaplastic-Lymphoma-Kinase-Positive Large-Cell Lymphoma of the Central Nervous System: Comprehensive Review of the Literature

Author

Colamaria, Antonio, primary, Leone, Augusto, additional, Carbone, Francesco, additional, Dallos Laguado, Yasser Andres, additional, Fochi, Nicola Pio, additional, Sacco, Matteo, additional, Fesce, Cinzia, additional, Sanguedolce, Francesca, additional, Giordano, Guido, additional, Iaconetta, Giorgio, additional, Spetzger, Uwe, additional, Coppola, Luigi, additional, De Santis, Elena, additional, Coppola, Giulia, additional, and De Notaris, Matteo, additional

Published
2023
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39. Real-life Data on Cefiderocol Efficacy and Safety to Treat Multidrug-Resistant Acinetobacter baumannii Infections

Author

Campogiani, Laura, primary, Crea, Angela Maria Antonia, additional, Minardi, Maria Letizia, additional, Ansaldo, Lorenzo, additional, Coppola, Luigi, additional, Compagno, Mirko, additional, Vitale, Pietro, additional, Spalliera, Ilaria, additional, Malagnino, Vincenzo, additional, Teti, Elisabetta, additional, D’agostini, C, additional, Pennacchiotti, Chiara, additional, Abate, Davide Natale, additional, Celeste, Maria Grazia, additional, Andreoni, Massimo, additional, Iannetta, Marco, additional, and Sarmati, Loredana, additional

Published
2023
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41. Could CT finding of gas in the sole mesenteric artery be a sign of a severe acute ischemia? Presentation of a rare fatal case and a literature review

Author

D'Agostino, Valerio, primary, Coppola, Luigi, additional, Barillaro, Angela, additional, Spaziano, Mariateresa, additional, Bonacci, Nicola, additional, Castaldo, Stefania, additional, Nappa, Ciro, additional, Iacuessa, Giovanna, additional, Cerrone, Fabio, additional, and Salzano, Antonio, additional

Published
2023
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47. Development and validation of a prediction score for failure to casirivimab/imdevimab in hospitalized patients with COVID-19 pneumonia.

Author

Cozzi-Lepri, Alessandro, Borghi, Vanni, Rotundo, Salvatore, Mariani, Bianca, Ferrari, Anna, Borgo, Cosmo Del, Bai, Francesca, Colletti, Pietro, Miraglia, Piermauro, Torti, Carlo, Cattelan, Anna Maria, Cenderello, Giovanni, Berruti, Marco, Tascini, Carlo, Parruti, Giustino, Coladonato, Simona, Gori, Andrea, Marchetti, Giulia, Lichtner, Miriam, and Coppola, Luigi

Published
2024
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48. PD-L1 testing in metastatic triple negative breast cancer: Results of an Italian survey

Author

Cerbelli, Bruna, primary, Cirillo, Alessio, additional, Pomati, Giulia, additional, Pernazza, Angelina, additional, Ascione, Andrea, additional, Pisegna, Simona, additional, Pisano, Annalinda, additional, Leopizzi, Martina, additional, Pignataro, Maria Gemma, additional, Costarelli, Leopoldo, additional, Mulè, Antonino, additional, Vecchione, Andrea, additional, Catalano, Piera, additional, Coppola, Luigi, additional, Perrone, Giuseppe, additional, Perracchio, Letizia, additional, Anemona, Lucia, additional, Mastracchio, Antonio, additional, Nardi, Stefano, additional, Reitano, Renato, additional, Massari, Annalisa, additional, Grillo, Lucia Rosalba, additional, Liberati, Fabrizio, additional, Della Rocca, Carlo, additional, Marchetti, Paolo, additional, Botticelli, Andrea, additional, and D’Amati, Giulia, additional

Published
2023
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50. Resistance to Ceftazidime/Avibactam in Klebsiella pneumoniae KPC-Producing Isolates: A Real-Life Observational Study

Author

Campogiani, Laura, primary, Vitale, Pietro, additional, Lodi, Alessandra, additional, Imeneo, Alessandra, additional, Fontana, Carla, additional, D’Agostini, Cartesio, additional, Compagno, Mirko, additional, Coppola, Luigi, additional, Spalliera, Ilaria, additional, Malagnino, Vincenzo, additional, Teti, Elisabetta, additional, Iannetta, Marco, additional, Andreoni, Massimo, additional, and Sarmati, Loredana, additional

Published
2023
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