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204 results on '"Coordination nationale"'

1. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 7 « Changements des conditions hydrographiques » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 7 « Changements des conditions hydrographiques » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

2. Synthèse de l’évaluation de l’atteinte du bon état écologique des Mammifères Marins au titre du descripteur 1 par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des Mammifères Marins au titre du descripteur 1 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

3. Synthèse de l’évaluation de l’atteinte du bon état écologique des habitats benthiques au titre des descripteurs 1 et 6 par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des habitats benthiques au titre des descripteurs 1 et 6 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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4. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 5 « Eutrophisation » par façade maritime. Fiche indicateur « Concentration en Chlorophylle-a dans la colonne d’eau » Région marine : Manche-Atlantique

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 5 « Eutrophisation » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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5. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 9 «Questions sanitaires» par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 9 « Questions sanitaires » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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6. Synthèse de l’évaluation de l’atteinte du bon état écologique des Reptiles (tortues marines) au titre du descripteur 1 par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des Reptiles (tortues marines) au titre du descripteur 1 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

7. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 3 « Espèces exploitées à des fins commerciales » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 3 « Espèces exploitées à des fins commerciales » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

8. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 10 « Déchets marins » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 10 « Déchets marins » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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9. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 11 « Perturbations sonores » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 11 « Perturbations sonores » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

10. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 6 « Intégrité des fonds marins » (critères D6C1, D6C2 et D6C3) par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 6 « Intégrité des fonds marins » (critères D6C1, D6C2 et D6C3) par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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11. Synthèse de l’évaluation de l’atteinte du bon état écologique des Poissons et Céphalopodes au titre du descripteur 1 par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des Poissons et Céphalopodes au titre du descripteur 1 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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12. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 2 « Espèces Non Indigènes » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 2 « Espèces Non Indigènes » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

13. Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 8 « Contaminants dans le milieu » par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique au titre du descripteur 8 « Contaminants dans le milieu » par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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14. Synthèse de l’évaluation de l’atteinte du bon état écologique des Oiseaux Marins au titre du descripteur 1 par façade maritime

Author: Ifremer and Coordination Nationale Directive Cadre Stratégie Pour Le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des Oiseaux Marins au titre du descripteur 1 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019

15. Synthèse de l’évaluation de l’atteinte du bon état écologique des habitats pélagiques au titre du descripteur 1 par façade maritime

Author: Ifremer, Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique, Ifremer, and Coordination Nationale Directive Cadre Stratégie pour le Milieu Marin, Bon Etat Ecologique
Abstract: Synthèse de l’évaluation de l’atteinte du bon état écologique des habitats pélagiques au titre du descripteur 1 par façade maritime : - Manche Est - mer du Nord - Nord Atlantique - Manche Ouest - Sud - Atlantique - Méditerranée
Published: 2019
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16. LA GÉOGRAPHIE RECENTRÉE: La planète humanisée, dans sa double dimension, naturelle, sociale

Author: Coordination Nationale des Géographes
Published: 1989

17. La santé périnatale en France métropolitaine de 1995 à 2010. Résultats des enquêtes nationales périnatales

Author: la Coordination nationale des Enquêtes Nationales Périnatales, François Goffinet, Béatrice Blondel, Nathalie Lelong, and M Kermarrec
Subjects: Maternity and Midwifery
Abstract: Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 41 - N° 2 - p. 151-166
Published: 2012

18. Quelques observations sur les 'semences' : de la protection des marchands de chandelles à la confiscation du vivant

Author: Berlan, Jean-Pierre, Coordination Nationale pour la Défense des Semences Fermières,Paris (FRA), ., Unité d'économie et sociologie rurales de Montpellier, Institut National de la Recherche Agronomique (INRA), Coordination nationale, Saisissez le nom du laboratoire, du service ou du département., Ville service., and ProdInra, Migration
Subjects: [SHS] Humanities and Social Sciences, ethique, biotechnologie, [SHS]Humanities and Social Sciences
Abstract: International audience; L'auteur se demande s'il n'existe pas une autre dynamique et une autre politique "semencières" à la fois plus efficaces scientifiquement, économiquement et socialement que celle consistant à privatiser le vivant.
Published: 1998

19. La géographie recentrée

Author: Coordination nationale des géographes
Subjects: Geography, Planning and Development, Earth-Surface Processes
Abstract: Coordination Nationale des GéographesCoordination Nationale des Géographes. La géographie recentrée. In: L'Espace géographique, tome 18, n°2, 1989. La géographie et ses enseignements. pp. 178-179.
Published: 1989

20. Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts

Author: Ernesto Martínez-Martínez, Enrique Santamaría, Frederic Jaisser, Joaquín Fernández-Irigoyen, Amaya Fernández-Celis, Natalia López-Andrés, Patrick Rossignol, Jaime Ibarrola, IDISNA, Pamplona, Centre de Recherche des Cordeliers (CRC), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RA), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble, Université Pierre et Marie Curie - Paris 6 (UPMC)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), French-Clinical Research Infrastructure Network [Lyon] (FCRIN INI-CRCT - Coordination Nationale Réseau FORCE), Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RH), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), HAL UPMC, Gestionnaire, Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre de Recherche des Cordeliers ( CRC ), Université Paris Diderot - Paris 7 ( UPD7 ) -École pratique des hautes études ( EPHE ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), French-Clinical Research Infrastructure Network [Lyon] ( FCRIN INI-CRCT - Coordination Nationale Réseau FORCE ), Centre de Recherche en Nutrition Humaine Rhône-Alpes - CRNH-RA-Centre Hospitalier Lyon Sud [CHU - HCL] ( CHLS ), and Hospices Civils de Lyon ( HCL ) -Hospices Civils de Lyon ( HCL )
Subjects: Proteomics, 0301 basic medicine, medicine.medical_specialty, Cardiac fibrosis, Galectin 3, Galectins, lcsh:Medicine, Down-Regulation, Context (language use), 030204 cardiovascular system & hematology, Biology, Article, Cell Line, law.invention, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Mediator, law, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Internal medicine, medicine, Humans, lcsh:Science, Aldosterone, Multidisciplinary, Myocardium, lcsh:R, Calcium-Binding Proteins, Blood Proteins, Fibroblasts, medicine.disease, Fibrosis, Angiotensin II, Recombinant Proteins, Cell biology, 030104 developmental biology, Endocrinology, [ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Proteome, Recombinant DNA, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Cytokines, lcsh:Q, Collagen, Reticulocalbin 1, CRISPR-Cas Systems
Abstract: Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix components, including collagens. Galectin-3 (Gal-3) and Cardiotrophin-1 (CT-1) are two profibrotic molecules that mediate Aldosterone (Aldo)-induced cardiac fibrosis. However the underlying mechanisms are not well defined. Our aim is to characterize changes in the proteome of human cardiac fibroblasts treated with Aldo, Gal-3 or CT-1 to identify new common proteins that might be new therapeutic targets in cardiac fibrosis. Using a quantitative proteomic approach in human cardiac fibroblasts, our results show that Aldo, Gal-3 and CT-1 modified the expression of 30, 17 and 89 proteins respectively, being common the reticulocalbin (RCN) family members. RCN-3 down-regulation triggered by Aldo, Gal-3 and CT-1 was verified. Treatment with recombinant RCN-3 decreased collagens expression in human cardiac fibroblasts through Akt phosphorylation. Interestingly, CRISPR/Cas9-mediated activation of RCN-3 decreased collagen production in human cardiac fibroblasts. In addition, recombinant RCN-3 blocked the profibrotic effects of Aldo, Gal-3 and CT-1. Interestingly, RCN-3 blunted the increase in collagens expression induced by other profibrotic stimuli, angiotensin II, in human cardiac fibroblasts. Our results suggest that RCN-3 emerges as a new potential negative regulator of collagen production and could represent a therapeutic target in the context of cardiac fibrosis.
Published: 2017

21. Higher education strategy in engineering to meet global technical challenges

Author: Bonnaud, Olivier, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Coordination Nationale de la Formation en Microélectronique (CNFM), and Centre National de la Recherche Scientifique (CNRS)
Subjects: [SPI]Engineering Sciences [physics], Microelectronics, Skills and know-how, Worldwide challenges, Learning and training, Digital society
Abstract: International audience; The strategy of teaching electrical engineering applied to microelectronics is undergoing a very strong evolution combining the development of the Internet and thus the globalization of digital technology and the experience of the pandemic on distance learning approaches. On the one hand, the meteoric development of digital technology is creating new challenges related to the saturation of data transfer networks and the associated consumption of electrical energy, which are growing exponentially. On the other hand, the use of digital technology in applied sciences during the pandemic has proven to be almost ineffective. The future engineers need knowledge and know-how in order to be efficient and innovative. This document deals in a first part with the technical and scientific needs applied to microelectronics and in a second part with the training strategy and the pedagogical approach which must imperatively optimize the use of digital technology by promoting well targeted actions.. These experiments were conducted within the French national microelectronics network, which includes 12 inter-university centers and covers all the specialties in the field, and which made it possible to test the interest and effectiveness of different approaches.
Published: 2022

22. REIN : un outil au service des patients

Author: Ayav, Carole, Raffray, Maxime, Béchade, Clémence, Couchoud, Cécile, Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Délégation à la Recherche Clinique et à l'Innovation [CHRU Nancy] (DRCI), Centre de Recherches sur l'Action Politique en Europe (ARENES), Université de Rennes (UR)-Institut d'Études Politiques [IEP] - Rennes-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Centre National de la Recherche Scientifique (CNRS), Recherche sur les services et le management en santé (RSMS), Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), École des Hautes Études en Santé Publique [EHESP] (EHESP), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Coordination Nationale Rein [Paris, France], and Agence de la biomédecine [Saint-Denis la Plaine]
Subjects: Épidémiologie, Public health, Registry, Patients, Epidemiology, Chronic kidney disease, Research, Registre, Maladie rénale chronique, Recherche, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Santé publique
Abstract: International audience; On the occasion of the 20th anniversary of the REIN (French Renal Epidemiology and Information Network), a summary work on the contributions of the national French ESKD register was carried out. On the issue of patients’ perspectives, the following key messages were retained. As shown by the SONG (Standardised Outcomes in Nephrology) initiative, the criteria for judging the dialysis treatment that patients and care-givers prefer are not those that are traditionally found in published studies. For example, for haemodialysis, they are fatigue, ability to travel, time without dialysis, impact on family and ability to work. The concern to give the patients a voice has been at the heart of the REIN registry right from the outset. In addition, there are patient representatives in the REIN Scientific Council and the Steering Group. Although mainly focused on quantitative health data collected from professionals, REIN has also supported studies pertaining to data collected directly from patients. These studies enable addressing questions pertaining to the problems faced by patients in their care pathway and their life with the disease. The setting up of a tool for routine and electronic collection of the patients’ point of view in the evaluation of their treatment and the support of patient-initiated research contribute to positioning the REIN as a partner tool at the service of patients, unique in France; À l’occasion des 20 ans du REIN (Réseau Epidémiologie et Information en Néphrologie), un travail de synthèse sur les apports du registre a été mené. Sur le point de vue des patients avec une maladie rénale stade 5, les messages clés suivants ont été retenus.L’initiative SONG (Standardised Outcomes in Nephrology) l’a montré, les critères de jugement de la prise en charge en dialyse que les patients et aidants privilégient ne sont pas ceux que l’on retrouve traditionnellement dans les études publiées. Par exemple, en hémodialyse, il s’agit de : la fatigue, la capacité à voyager, le temps sans dialyse, l’impact sur la famille et la capacité à travailler.La préoccupation de donner la parole aux patients a d’emblée été au cœur du registre REIN. En outre, des représentants de patients siègent au conseil scientifique REIN et au sein du groupe de pilotage.Bien qu’essentiellement orienté sur des données de santé quantitatives recueillies auprès des professionnels, REIN a également soutenu les études portant sur des données recueillies directement auprès des patients. Ces études permettent d’aborder des questions proches des problématiques des patients sur leurs parcours de soins et leur vie avec la maladie.La mise en place d’un outil de recueil électronique et de routine du point de vue des patients dans l’évaluation de leur prise en charge et le soutien de recherches à l’initiative des patients participent à positionner le REIN comme outil partenaire au service des patients, unique en France.
Published: 2022

23. REIN : un outil au service de l’éclairage des inégalités en santé

Author: Chatelet, Valérie, Bayat, Sahar, Driollet, Bénédicte, Merle, Véronique, Moranne, Olivier, Lassalle, Mathilde, Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), École des Hautes Études en Santé Publique [EHESP] (EHESP), Département Méthodes quantitatives en santé publique (METIS), Centre de Recherches sur l'Action Politique en Europe (ARENES), Université de Rennes (UR)-Institut d'Études Politiques [IEP] - Rennes-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Centre National de la Recherche Scientifique (CNRS), Recherche sur les services et le management en santé (RSMS), Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Rouen, Normandie Université (NU), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Institut Desbrest de santé publique (IDESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Agence de la biomédecine [Saint-Denis la Plaine], and Coordination Nationale Rein [Paris, France]
Subjects: Registry, Public health, Inequities, Réseau Epidémiologie et Information en Néphrologie (REIN), Chronic kidney disease, Registre, Maladie rénale chronique, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Santé publique, Inégalités
Abstract: International audience; On the occasion of the 20th anniversary of the REIN (French Renal Epidemiology and Information Network), a summary work on the contributions of the national French ESKD register was carried out. On the issue of Social Inequalities in Health, the following key messages were retained.Social inequalities in health exist throughout the journey of a patient with chronic kidney disease and manifest as territorial inequalities in access to home-based or independent dialysis treatment and to transplant, whether preemptive or otherwise.SIH are observed in adults as well as in the paediatric population.The female gender appears to be associated with a disparity in access to kidney transplant.; À l’occasion des 20 ans du REIN (Réseau Epidémiologie et Information en Néphrologie), un travail de synthèse sur les apports du registre a été mené. Sur la question des inégalités sociales de santé, les messages clés suivants ont été retenus.Les inégalités sociales de santé existent tout au long du parcours du patient atteint d’une maladie rénale chronique et se traduisent par des inégalités territoriales d’accès au traitement par dialyse au domicile ou autonome, à la greffe qu’elle soit préemptive ou non.Les ISS sont retrouvées chez l’adulte mais aussi dans la population pédiatrique.Le genre féminin semble associé à une disparité d’accès à la greffe rénale.
Published: 2022

24. The limits of the digitalization of the training of engineers and masters in microelectronics

Author: Bonnaud, Olivier, Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Institut d'Électronique et des Technologies du numéRique (IETR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - pôle Sciences et technologie, and Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)
Subjects: digital society limitations, [SPI]Engineering Sciences [physics], microelectronics, pedagogical approach, digital tools
Abstract: International audience; In an increasingly digitalized technological environment, in a temporary context of pandemic and in a strategy of governments to minimize the costs of student training, the ministries of higher education are increasingly organizing the digitalization of all training in the hope of reducing the operating and salary costs of higher education institutions. While for some disciplines this objective may be tolerable, in the training of engineering degrees, it appears dangerous in terms of its effect on the competence and quality of the students. They will have to face many technological and societal challenges and will therefore be expected to have in-depth knowledge and know-how. This article highlights the skills needed to meet the various current challenges, the forecasts for the development of tools for generalized training in digital form, and the limitations of this approach on the actual skills and know-how of the students and users trained. Coordination with the French national network of higher education in microelectronics is a way to evaluate the effectiveness of digital tools in the acquisition of know-how.
Published: 2022

25. Technical and pedagogical challenges in micro-nanoelectronics for facing upcoming digital society

Author: Bonnaud, Olivier, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), French Ministry of Higher Education, IDEFI-FINMINA project [ANR-11-IDFI-0017], and ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011)
Subjects: [SPI]Engineering Sciences [physics], micronanoelectronics, electronics circuits and systems, electronics engineering education, challenges of connected society
Abstract: International audience; The worldwide evolution towards a digital society is strongly underway, thanks in particular to the incredible increase in the performance of electronics and micronanoelectronics in all their compartments, from elementary components to circuits and systems. This accelerating evolution, especially in terms of data flow corresponding to the multiplication of connected objects, raises new challenges of two kinds: technical/technological and human. On the technical side, we need to reduce the size of systems and their energy consumption by controlling elementary devices and circuit architectures. On the human level, we need to adapt skills to the new technical and technological challenges and above all to increase the pool of talent due to the extremely rapid development of applications, despite the growing assistance provided by all the design and manufacturing assistance tools. After having developed the global context, this paper focuses on the different limitations and associated challenges and on the approach brought by the French microelectronics training network for the learning of the know-how in connection with the recovery plans dedicated to the electronics industry.
Published: 2022

26. Estimating the burden of influenza-related and associated hospitalizations and deaths in France: An eight-season data study, 2010-2018

Author: Magali Lemaitre, Fouad Fayssoil, Fabrice Carrat, Pascal Crepey, Jacques Gaillat, Gaetan Gavazzi, O. Launay, Anne Mosnier, Marie-Cecile Levant, Mathieu Uhart, IQVIA, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), École des Hautes Études en Santé Publique [EHESP] (EHESP), Département Méthodes quantitatives en santé publique (METIS), Recherche en Pharmaco-épidémiologie et Recours aux Soins (REPERES), Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP), Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois], CHU Grenoble, CIC Cochin Pasteur (CIC 1417), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôtel-Dieu-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Réseau des Groupes Régionaux d'Observation de la Grippe (GROG), Coordination nationale, Sanofi Pasteur [Lyon, France], Sanofi, and Gestionnaire, HAL Sorbonne Université 5
Subjects: Pulmonary and Respiratory Medicine, Epidemiology, Incidence, Public Health, Environmental and Occupational Health, mortality, Hospitalization, Infectious Diseases, Cost of Illness, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Influenza, Human, Humans, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, France, human, Seasons
Abstract: International audience; BackgroundIn France, each year, influenza viruses are responsible for seasonal epidemics leading to 2–6 million cases. Influenza can cause severe disease that may lead to hospitalization or death. As severe disease may be due to the virus itself or to disease complications, estimating the burden of severe influenza is complex. The present study aimed at estimating the epidemiological and economic burden of severe influenza in France during eight consecutive influenza seasons (2010–2018).MethodsInfluenza-related hospitalization and mortality data and patient characteristics were taken from the French hospital information database, PMSI. An ecological approach using cyclic regression models integrating the incidence of influenza syndrome from the Sentinelles network supplemented the PMSI data analysis in estimating excess hospitalization and mortality (CépiDc—2010–2015) and medical costs.ResultsEach season, the average number of influenza-related hospitalizations was 18,979 (range: 8627–44,024), with an average length of stay of 8 days. The average number of respiratory hospitalizations indirectly related with influenza (i.e., influenza associated) was 31,490 (95% confidence interval [CI]: 24,542–39,012), with an average cost of €141 million (range: 54–217); 70% of these hospitalizations and 77% of their costs concerned individuals ≥65 years of age (65+). More than 90% of excess mortality was in 65+ subjects.ConclusionsThe combination of two complementary approaches allowed estimation of both influenza-related and associated hospitalizations and deaths and their burden in France, showing the substantial impact of complications. The present study highlighted the major public health burden of influenza and its severe complications, especially in 65+ subjects.
Published: 2021

27. La filière électronique: enjeu industriel et défis pour la formation

Author: Gilles Rizzo, Sandrine Beaufils, Virginie HOEL, Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Circuits Systèmes Applications des Micro-ondes - IEMN (CSAM - IEMN ), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), and Université catholique de Lille (UCL)-Université catholique de Lille (UCL)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA)
Subjects: stomatognathic diseases, [SPI]Engineering Sciences [physics]
Abstract: oralSession: Conseil d’orientation du CNFM; National audience
Published: 2021

28. A comparison of coronavirus disease 2019 and seasonal influenza surveillance in five European countries: France, Germany, Italy, Spain and the United Kingdom

Author: Thierry Rigoine de Fougerolles, Joan Puig‐Barbera, George Kassianos, Philippe Vanhems, Jorg Schelling, Pascal Crepey, Raul Ortiz Lejarazu, Filippo Ansaldi, Markus Fruhwein, Cristina Galli, Anne Mosnier, Elena Pariani, Anvar Rasuli, Olivier Vitoux, John Watkins, Thomas Weinke, Hélène Bricout, Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Ludwig-Maximilians-Universität München (LMU), École des Hautes Études en Santé Publique [EHESP] (EHESP), Université de Rennes (UR), Universidad de Valladolid [Valladolid] (UVa), Università degli studi di Genova = University of Genoa (UniGe), Università degli Studi di Milano = University of Milan (UNIMI), Réseau des Groupes Régionaux d'Observation de la Grippe (GROG), Coordination nationale, Sanofi Pasteur [Lyon, France], Cardiff University, and Klinikum Ernst von Bergmann [Potsdam, Germany] (KEVB)
Subjects: Pulmonary and Respiratory Medicine, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, surveillance, Public Health, Environmental and Occupational Health, COVID-19, United Kingdom, burden, Europe, Infectious Diseases, Italy, Spain, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Germany, Influenza, Human, Humans, epidemiology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, France, Seasons, influenza, Pandemics
Abstract: Background\ud In response to the coronavirus disease (COVID-19) outbreak that unfolded across Europe in 2020, the World Health Organisation (WHO) called for repurposing existing influenza surveillance systems to monitor COVID-19. This analysis aimed to compare descriptively the extent to which influenza surveillance systems were adapted and enhanced and how COVID-19 surveillance could ultimately benefit or disrupt routine influenza surveillance.\ud \ud Methods\ud We used a previously developed framework in France, Germany, Italy, Spain and the United Kingdom to describe COVID-19 surveillance and its impact on influenza surveillance. The framework divides surveillance systems into seven subsystems and 20 comparable outcomes of interest and uses five evaluation criteria based on WHO guidance. Information on influenza and COVID-19 surveillance systems were collected from publicly available resources shared by European and national public health agencies.\ud \ud Results\ud Overall, non-medically attended, virological, primary care and mortality surveillance were adapted in most countries to monitor COVID-19, although community, outbreak and hospital surveillance were reinforced in all countries. Data granularity improved, with more detailed demographic and medical information recorded. A shift to systematic notification for cases and deaths enhanced both geographic and population representativeness, although the sampling strategy benefited from the roll out of widespread molecular testing. Data communication was greatly enhanced, contributing to improved public awareness.\ud \ud Conclusions\ud Well-established influenza surveillance systems are a key component of pandemic preparedness, and their upgrade allowed European countries to respond to the COVID-19 pandemic. However, uncertainties remain on how both influenza and COVID-19 surveillance can be jointly and durably implemented.
Published: 2021

29. National recovery plan for the electronics industry in France; importance of training in the field

Author: Olivier Bonnaud, Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), French Ministry of Higher Education, IDEFI-FINMINA project [ANR-11-IDFI-0017], Maga, Hajek, ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: Technological challenges, Higher education, 9. Industry and infrastructure, business.industry, Economic sector, 010102 general mathematics, Microelectronics industries, Context (language use), Plan (drawing), 01 natural sciences, Training (civil), 010305 fluids & plasmas, knowledge and know-how, [SPI]Engineering Sciences [physics], Work (electrical), 0103 physical sciences, Production (economics), Business, 0101 mathematics, Industrial Revolution, Industrial organization
Abstract: The world has witnessed an exponential development of digital technology with the advent of connected objects and the Internet of Things. All economic sectors are affected, leading to the fourth industrial revolution, called “Industry 4.0”, which all industrialized countries are seeking to develop. In parallel, the global evolution of the microelectronics industry has strongly evolved during the last 20 years, towards mass production in the far East. The European companies have thus oriented their activities towards design without manufacturing. This evolution if it seemed economically interesting has led to the loss of knowledge and especially knowhow at the European level, namely at the French one. In a situation of economic and sanitary crisis, supply difficulties have resulted in the definition of a strategy to boost production that is the goal of the new national recovery plan. In this context, it is necessary to build new plants but also to have the skills and know-how. The training of engineers, masters and technicians is of utmost importance. After having detailed the context and the needs manifested by the electronics and microelectronics sector, this paper deals with the approach of the national microelectronics training network to face these challenges which are as well French as European.11This work is financially supported by the French Ministry of Higher Education. Several realizations were obtained in the frame of the project IDEFI-FINMINA: by the IDEFI-FINMINA project, ANR-11-IDFI-0017.
Published: 2021

30. Distance learning is not an online face-to-face – Observations in microelectronic education

Author: Olivier Bonnaud, Laurent Fesquet, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Circuits, Devices and System Integration (CDSI), Techniques de l'Informatique et de la Microélectronique pour l'Architecture des systèmes intégrés (TIMA), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre Interuniversitaire de Micro-Electronique (CIME), Institut National Polytechnique de Grenoble (INPG), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), and Circuits, Devices and System Integration (TIMA-CDSI)
Subjects: 4. Education, distance learning, PACS 85.42, microelectronics, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics
Abstract: International audience; Due to the pandemic in early 2020, the French government, like many others, decided to temporarily close the universities and asked the faculties to entirely focus on online education or e-learning. In a world where digital contents exponentially increase, this pandemic has been an opportunity to develop distance e-learning. Many politicians found a unique opportunity to decrease or even eliminate face-to-face teaching activities. In engineering, this experience has shown clear limits and weaknesses. This paper highlights several problems that raised in microelectronic education and good reasons to move back to face-to-face learning especially for the acquisition of know-how. Indeed, know-how is mandatory for engineers, masters and PhDs in science and technology and this will never be replaced by a virtual experience. Real practice is the necessary price to pay for meeting the technological challenges of the upcoming decade.
Published: 2021

31. Vascular access cannulation and haemostasis: a national observational study of French practices

Author: Thierry Hannedouche, Marion Sallée, Jan-Marc Charrel, Bruno Guéry, Didier Borniche, Guillaume Jean, Lucile Mercadal, Philippe Brunet, Frank Le Roy, HAL-SU, Gestionnaire, Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Service de Néphrologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Clinique Charcot, Service de néphrologie adultes [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), French Association of Nurses for Dialysis, Transplantation and Nephrology , (AFIDTN), Coordination Nationale Rein [Paris, France], Agence de la biomédecine [Saint-Denis la Plaine], Service de néphrologie et hémodialyse [CHU de Strasbourg], CHU Strasbourg, Centre d'Investigation Clinique [CHU Rouen] (CIC Rouen), Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de néphrologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Charles Nicolle [Rouen]-CHU Rouen, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Necker - Enfants Malades [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Subjects: medicine.medical_specialty, cannulation, medicine.medical_treatment, 030232 urology & nephrology, Vascular access, Arteriovenous fistula, 030204 cardiovascular system & hematology, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, 03 medical and health sciences, 0302 clinical medicine, medicine, AcademicSubjects/MED00340, Hemostatic function, arteriovenous fistula, Dialysis, Transplantation, Local anaesthetic, business.industry, vascular access, Original Articles, catheter, medicine.disease, [SDV.MHEP.UN] Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, 3. Good health, Surgery, haemodialysis, Catheter, Nephrology, haemostasis, dialysis, Observational study, Hemodialysis, business
Abstract: Background We report the results of an observational study of arteriovenous fistula (AVF) cannulation and haemostasis practices in France. Methods The study (sponsored by Brothier Pharmaceutical Inc.) was conducted in 150 dialysis units. Data obtained from 150 supervisory nurses, 1538 nurses and 3588 patients with an AVF were analysed. Results The nurses reported using rope-ladder, area or buttonhole cannulation techniques in 68, 26 and 6% of cases, respectively. Metal needles were used most frequently (64%), with mainly a diameter of 15 G or 16 G. The needle was introduced with the bevel up in 56% of cases. Compression applied using dressings (in particular, pure calcium alginate dressings) was the method of choice for haemostasis of the puncture sites and was assessed as being strong by most of the nurses and very strong in cases of prolonged bleeding. Most (82%) of the patients reported the use of local anaesthetic before cannulation and 23% reported an allergic skin reaction to the anaesthetic. Bleeding of the puncture sites lasted for >10 min for 48% of the patients and it reappeared between two sessions for 29% of the patients. Whereas the nurses appeared to have a good understanding of AVF, more than half of the patients did not know how to care for it, with 55% requiring more information. Conclusions This study underlines the lack of national consensus concerning AVF cannulation practices. It suggests that haemostasis methods of the puncture sites can be improved and it highlights the need to improve patient knowledge.
Published: 2021

32. Can empathy be taught? A cross-sectional survey assessing training to deliver the diagnosis of end stage renal disease

Author: Eve Vilaine, Ziad A. Massy, Yosu Luque, Odile Basse, Xavier Belenfant, Eric Rondeau, Wided Tabbi, Hélène François, Alice Doreille, Emmanuelle Corruble, Dan Benhamou, Urgences néphrologiques et transplantation rénale [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Ambroise Paré [AP-HP], Centre Hospitalier Intercommunal André Grégoire [Montreuil] (CHI André Gregoire), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Coordination Nationale Rein [Paris, France], Agence de la biomédecine [Saint-Denis la Plaine], Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), HAL-SU, Gestionnaire, Service d'Urgences néphrologiques et transplantation rénale [CHU Tenon], CHU Tenon [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Subjects: Male, Nephrology, Cross-sectional study, Failure diagnosis, Health Care Providers, 030232 urology & nephrology, Social Sciences, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, 0302 clinical medicine, Primary outcome, Sociology, Chronic kidney disease, Medicine and Health Sciences, Medicine, Medical Personnel, 030212 general & internal medicine, media_common, Multidisciplinary, Education, Medical, 3. Good health, Professions, Patient Satisfaction, Educational Status, Female, Anatomy, Research Article, Medical education, medicine.medical_specialty, Medical curriculum, Patients, Science, media_common.quotation_subject, [SHS.EDU]Humanities and Social Sciences/Education, [SHS.EDU] Humanities and Social Sciences/Education, education, Empathy, Education, End stage renal disease, 03 medical and health sciences, Intervention (counseling), Internal medicine, Physicians, Renal Diseases, Humans, Physician-Patient Relations, business.industry, Biology and Life Sciences, Kidneys, Renal System, Medical dialysis, [SDV.MHEP.UN] Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, Trainees, Health Care, Cross-Sectional Studies, People and Places, Physical therapy, Kidney Failure, Chronic, Population Groupings, business, Medical Humanities
Abstract: Background Receiving the diagnosis of kidney failure has a major impact on patients. Yet, the way in which this diagnosis should be delivered is not formally taught within our medical curriculum. To fill this gap we set up a training course of kidney failure diagnosis delivery for nephrology trainees since 2016. This study assessed the effectiveness of this educational intervention. Methods The primary outcome was change in the empathy score immediately after the training session and several months afterward, based on the Jefferson Scale of Physician Empathy (JSPE). Self-reported change in clinical practice was also evaluated. As control groups, we assessed empathy levels in untrained nephrology trainees (n = 26) and senior nephrologists (n = 71). Later on (>6 months) we evaluated participants’ perception of changes in their clinical practice due to the training. Results Six training sessions permitted to train 46 trainees. Most respondents (76%) considered the training to have a durable effect on their clinical practice. Average empathy scores were not significantly different in pre-trained trainees (average JSPE: 103.7 ± 11.4), untrained trainees (102.8 ± 16.4; P = 0.81) and senior nephrologists (107.2 ± 13.6; P = 0.15). Participants’ empathy score significantly improved after the training session (112.8 ± 13.9; P = 0.003). This improvement was sustained several months afterwards (average JSPE 110.5 ± 10.8; P = 0.04). Conclusion A single 4-hour training session can have long lasting impact on empathy and clinical practice of participants. Willingness to listen, empathy and kindness are thought to be innate and instinctive skills, but they can be acquired and should be taught.
Published: 2021

33. Teaching Hardware Security: Earnings of an Introduction Proposed as an Escape Game

Author: Beatrice Pradarelli, Lionel Torres, Florent Bruguier, Loic Dalmasso, Emmanuelle Lecointre, Pascal Benoit, ADAptive Computing (ADAC), Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Institut Universitaire Technologique de Nîmes (IUT [Nîmes]), IUT de Nîmes, Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), and TEST (TEST)
Subjects: Hardware security module, Acquiring skills, Computer science, Data Security, Data security, Cryptography, Context (language use), Serious game, Computer security, computer.software_genre, Education, Escape Game, 03 medical and health sciences, 0302 clinical medicine, Security Course, ComputingMilieux_COMPUTERSANDEDUCATION, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, Hard- ware Security, Serious Game, 030304 developmental biology, 0303 health sciences, Earnings, business.industry, 030220 oncology & carcinogenesis, Security, business, Internet of Things, computer
Abstract: International audience; The Internet of Things (IoT) sees the appearance of ever more connected objects. In such a context, the security aspect of these objects is more relevant than ever. That's why we have developed several courses about hardware security. Traditional security courses often start with a catalog of definitions that can sometimes be boring for students and therefore counterproductive. This study describes an escape game used as a sequence to introduce several security concepts. This serious game could be adapted according to the degree level of the students. Results show a significant improvement in acquiring skills for the students who plays to the escape game. All the contents of this course are open sourced and could be freely available on request.
Published: 2020

34. Adaptation of the higher education in engineering to the advanced manufacturing technologies

Author: Olivier Bonnaud, Ahmad Bsiesy, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Centre Interuniversitaire de Micro-Electronique (CIME), Institut National Polytechnique de Grenoble (INPG), ANR-11-IDFI-0017, Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), and Université de Nantes (UN)-Université de Rennes 1 (UR1)
Subjects: Engineering, Environmental Engineering, General Computer Science, Higher education, Energy Engineering and Power Technology, 01 natural sciences, Engineering education, [SPI]Engineering Sciences [physics], Microelectronics, Management of Technology and Innovation, 0103 physical sciences, lcsh:Technology (General), Advanced manufacturing, 0101 mathematics, 010306 general physics, Adaptation (computer science), 9. Industry and infrastructure, Renewable Energy, Sustainability and the Environment, business.industry, 4. Education, 010102 general mathematics, General Engineering, Industry 4.0, Network structuring, Engineering management, Multidisciplinarity, 8. Economic growth, lcsh:T1-995, business
Abstract: International audience; The 21st century will be the era of the fourth industrial revolution with the progressive introduction of the digital society, with smart/connected objects, smart factories that are driven by robotics, the Internet of Things (IoT) and artificial intelligence. Manufacturing is expected to be performed by smart factories, i.e. the industry 4.0, which is the outcome of steady development of information technology associated with new objects and systems that can automatically supervise and fulfil manufacturing tasks. The industry 4.0 concept relies largely on the ability to design and manufacture smart and connected devices that are based on microelectronics technology. This evolution requires highly-skilled technicians, engineers and PhDs, all of them well prepared for research, development and manufacturing. Their training, which combines knowledge and the associated compulsory know-how, is becoming the main challenge for the academic world. The curricula must therefore include the basic knowledge and associated know-how training in all the specialties of the field. The software and hardware tools used in microelectronics education are becoming highly complex and expensive that the most viable solution for practical training is to share technical facilities and human resources. This strategy has been adopted by the French microelectronics education network, which includes twelve universities and two industrial unions. By sharing human resources and technical facilities, the CNFM network was able to minimize the costs and to train future graduates on up-to-date tools similar to those used in companies. This paper aims to show how the strategy adopted by the French network can help meeting the needs of the future industry 4.0. Several examples of innovative activities developed in this strategy will be given. © 2020 by the authors. Licensee TAETI, Taiwan.
Published: 2020

35. Les systèmes neuroinspirés appliqués à la vision artificielle : pédagogie et interdisciplinarité

Author: Henniquau, D., Christel Vanbesien, Falez, P., Devienne, P., Alexis Vlandas, Cappy, A., Virginie HOEL, Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Circuits Systèmes Applications des Micro-ondes - IEMN (CSAM - IEMN ), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Bio-Micro-Electro-Mechanical Systems - IEMN (BIOMEMS - IEMN), Advanced NanOmeter DEvices - IEMN (ANODE - IEMN), Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), Université catholique de Lille (UCL)-Université catholique de Lille (UCL)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 (CRIStAL), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Nous remercions toute l’équipe de l’Xperium : Ils nous ont accueillis, conseillés, soutenus financièrement, aidés pour la conception et la mise en place du stand. Enfin, nous remercions tout particulièrement les chercheurs du projet SPINE ainsi que les chercheurs et doctorants impliqués de l’université de Lille, du CNRS, membres des laboratoires IEMN, CRIStAL et de l’IRCICA., and SPINE
Subjects: Neurone et synapse artificiels, stomatognathic diseases, [SPI]Engineering Sciences [physics], traitement d’images, logiciel de simulation, circuit électronique, apprentissage
Abstract: oralSession: la filière dans un contexte de développement durable et responsabilité sociétale; National audience; Le traitement neuroinspiré de l’information et le domaine des neurobiosystèmes sont deux pans de la recherche à fort potentiel de développement. Appliquées au domaine de la vision artificielle, elles visent au développement de nouvelles applications comme la conception d’implants rétiniens et/ou de caméras « intelligentes ». Des actions sont menées dans le domaine de la médiation scientifique et de la formation, au travers d’un stand à l’Xpérium et le développement d’une nouvelle unité d’enseignement (UE) appelée « Neuroengineering », intégrée au parcours de formation du Master « Biotechnologies » proposé à l’université de Lille. Le stand présenté à l’Xpérium montre à des jeunes lycéens et étudiants que l’utilisation d’architectures neuroinspirées dans un système de vision artificielle doit conduire à une forte amélioration des performances associée à une réduction de la consommation énergétique. Il s’agit d’une expérience pédagogique innovante auprès des jeunes générations montrant les enjeux des activités de recherche en construction dans les laboratoires. Pour l’UE Neuroengineering, les sujets abordés en séance permettent d’amener les étudiants vers la compréhension des Trends and challenges in neuroengineering (1), notamment en posant la question du développement de neuroprothèses électroniques intelligentes permettant une communication bidirectionnelle entre des neurones vivants et artificiels.
Published: 2022

36. AMUSE : un escape game pour la sécurité numérique

Author: Bruguier, Florent, Dalmasso, Loïc, Benoit, Pascal, Pradarelli, Béatrice, ADAptive Computing (ADAC), Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Coordination Nationale de la Formation en Microélectronique (CNFM), and Centre National de la Recherche Scientifique (CNRS)
Subjects: Escape Game, Security Course, Data Security, Security, Cryptography, Hardware Security, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, Serious Game, Education
Abstract: National audience; Un escape game de 7 à 99 ans pour découvrir les concepts de la cryptographie ! Vous êtes en quête de défi ? Arriverez-vous à ouvrir le coffre-fort en trouvant son code secret en moins de 5 minutes ? Vous n'aurez à votre disposition qu'une mallette renfermant des indices. En appliquant les concepts de la cryptographie, ces indices vous permettront de résoudre les énigmes qui vous conduiront au code secret. Concentration, mémorisation, logique et réactivité vous seront nécessaires pour défier le temps et battre le record. L'objectif de ce jeu sérieux est d'introduire tous les concepts nécessaires à l'apprentissage de la sécurité numérique. Il permet à travers le jeu de sensibiliser les étudiants aux notions nécessaires à appréhender le monde numérique de demain et sa sécurité. Ce jeu est simple et facile d'accès et permet de renforcer l'intérêt des étudiants pour l'enseignement dispensé. Concentration, mémorisation, logique et réactivité vous seront nécessaires pour défi er le temps et battre le record. Ce « Serious Game » est au cœur d'un processus pédagogique qui comprend plusieurs étapes : • Bilan des connaissances en cryptographie pour les stagiaires (collégiens, lycéens, étudiants, doctorant, personnel académique et privé) en début de séance • Découverte en groupe des principaux concepts et méthodes de cryptage de l'information en lisant un poster et en répondant à un questionnaire • Mise en pratique des acquis théoriques avec le « Serious Game » • Bilan des compétences en cryptographie en fin de séance.
Published: 2019

37. Survival and specific outcome of sickle cell disease patients after renal transplantation

Author: Laetitia Albano, Philippe Gataut, Nacera Ouali, Arnaud Lionet, Anissa Moktefi, Marie-Julia Ziliotis, Marie Matignon, Magali Louis, Philippe Grimbert, Alyette Duquesne, Marine Novion, Dany Anglicheau, Christel Gérardin, Karine Dahan, Pablo Bartolucci, Carmen Lefaucheur, Anoosha Habibi, Alexandre Karras, Arnaud Del Bello, Frédéric Galactéros, Cécile Couchoud, Vincent Audard, Lucile Figueres, service Anatomie et Cytologie Pathologique, Hôpital Henri Mondor, Assistance Publique - Hôpitaux de Paris (AP-HP), Coordination Nationale Rein [Paris, France], Agence de la biomédecine [Saint-Denis la Plaine], Remodelage et Reparation du Tissu Renal, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de néphrologie [Rennes], CHU Pontchaillou [Rennes]-Hôpital Pontchaillou-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Service Néphrologie et transplantation rénale Adultes [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Paris Translational Research Center for Organ Transplantation & Department of Nephrology and Transplantation, Université Paris Diderot - Paris 7 (UPD7)-Hopital Saint-Louis [AP-HP] (AP-HP), Institut de transplantation urologie-néphrologie (ITUN), Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes), Service de néphrologie et transplantation rénale [Nice], Hôpital Pasteur [Nice] (CHU), Université de Lille, Département de Néphrologie et Transplantation d'organes, Hôpital de Rangueil, CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10, CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Unité des maladies génétiques du globule rouge, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Albert Chenevier-groupe hospitalier Hendi Mondor, Centre de référence des syndromes drépanocytaires majeurs, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor, Protéines de la membrane érythrocytaire et homologues non-érythroides, Université des Antilles et de la Guyane (UAG)-Institut National de la Transfusion Sanguine [Paris] (INTS)-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de néphrologie et transplantation, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université de Rennes (UR)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Département de Néphrologie et Transplantation d'organes [CHU Toulouse], Pôle Urologie - Néphrologie - Dialyse - Transplantations - Brûlés - Chirurgie plastique - Explorations fonctionnelles et physiologiques [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], Département de Néphrologie et Transplantation d'organes [Toulouse], CHU Toulouse [Toulouse], and Le Bihan, Sylvie
Subjects: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Cell, Congenital cytomegalovirus infection, Anemia, Sickle Cell, Kaplan-Meier Estimate, Disease, Opportunistic Infections, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, patient survival, hemic and lymphatic diseases, Internal medicine, Humans, Medicine, infections, Kidney transplantation, Dialysis, Retrospective Studies, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, business.industry, Graft Survival, Significant difference, Patient survival, Hematology, Middle Aged, renal transplantation, medicine.disease, Kidney Transplantation, 3. Good health, Transplantation, medicine.anatomical_structure, Case-Control Studies, 030220 oncology & carcinogenesis, Kidney Failure, Chronic, Female, sickle cell disease, France, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Follow-Up Studies, 030215 immunology
Abstract: International audience; The prognosis of sickle cell disease (SCD) patients who need dialysis is poor, but experience with kidney transplantation is limited. This study assessed the characteristics of 36 SCD patients undergoing renal transplantation. Immediate post-surgical complications occurred in 25% of cases. Cytomegalovirus and bacterial infections were frequently observed. Twelve patients died after a median follow-up period of17-4 months. Overall patient survival was significantly lower in SCD than in the control group without significant difference for overall death-censored graft sur-vival. Our data suggest that renal transplantation should be systematically considered in SCD patients with end-stage renal disease.
Published: 2019

38. SP678 Study of the Pre-dialysis Care Trajectory of End-Stage Renal Disease Patients Starting Dialysis in Emergency in France

Author: Adélaïde Pladys, Cécile Vigneau, S. Bayat, Cécile Couchoud, Fei Gao, Maxime Raffray, Recherche en Pharmaco-épidémiologie et Recours aux Soins (REPERES), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP), École des Hautes Études en Santé Publique [EHESP] (EHESP), Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (FEMTO-ST), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale Rein [Paris, France], Agence de la biomédecine [Saint-Denis la Plaine], Laboratoire d'Informatique Médicale (LIM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP), Département Méthodes quantitatives en santé publique (METIS), Université de Rennes (UR), EA Management des Organisations de Santé (EA MOS), École des Hautes Études en Santé Publique [EHESP] (EHESP)-PRES Sorbonne Paris Cité, and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
Subjects: Transplantation, medicine.medical_specialty, Chronicdialysis procedure, business.industry, medicine.medical_treatment, Pre-dialysis, Kidney failure, 3. Good health, End stage renal disease, Nephrology, Hemodialysis, Emergency medicine, medicine, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Dialysis (biochemistry), business
Abstract: International audience; INTRODUCTION: According to the French Renal Epidemiology and Information Network (REIN) registry data, in 2016, 32% of incident dialyzed patients started dialysis in emergency. The notion of emergency dialysis is defined as a first dialysis session performed immediately (within 24 hours) after the nephrologist’s assessment due to a life-threatening risk. Starting dialysis in emergency (ES) is associated with poorer outcome compared to a planned start (PS). Higher risk of morbidity and mortality, decreased quality of life for the patient as well as an increased cost for the health care system. The aim of this study was to compare the pre-dialysis care trajectory between ES and PS patients.METHODS: Data from the French REIN registry linked with the French national health database (SNIIRAM) were used. Patients aged 18 years old and older who started dialysis in 2015 in France were included. Individual characteristics at dialysis initiation, inpatient stays (number, duration and diagnosis), as well as consultations with general practitioners and nephrologists during the year before dialysis start were compared between ES and PS patients. The inpatient stays during which the dialysis started were not included in the comparison.RESULTS: Among the 10667 patients who started dialysis in 2015 in France, 9627 (90,2%) were linked to the SNIIRAM. The context of the first dialysis (ES or PS) was known for 9052 (84,9%) patients. Among them, 2769 (30,6%) had started dialysis in emergency. These patients had more comorbidities than the patients starting in a planned manner (for example, 19 % of ES patients had 3 or more cardio-vascular diseases versus 12,6 % of PS patients, p
Published: 2019

39. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

Author: Jean-Philippe Haymann, Emmanuel Letavernier, Emmanuelle Vidal-Petiot, Martin Flamant, H. Fessi, Christian Jacquot, Jean-Jacques Boffa, Caroline du Halgouet, Pascal Houillier, Marion Vallet, Sandra Wagner, Gérard Maruani, Renaud de la Faille, François Vrtovsnik, Pierre Ronco, Eric Thervet, Eric Daugas, Marine Livrozet, Laurence Nicolet-Barousse, Marie Metzger, Bénédicte Stengel, Nahid Tabibzadeh, Alexandre Karras, Service d'Explorations fonctionnelles multidisciplinaires [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Tenon [APHP], Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), French-Clinical Research Infrastructure Network [Lyon] (FCRIN INI-CRCT - Coordination Nationale Réseau FORCE), Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RH), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Service de Physiologie [Bichat-Claude Bernard], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Service de Physiologie [Georges-Pompidou], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5), Remodelage et Reparation du Tissu Renal, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunopathologie rénale, récepteurs et inflammation, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, CHU Tenon [APHP], Service de Néphrologie et Dialyses [CHU Tenon], Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Service de Néphrologie et Hémodialyse [CHU HEGP], Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, F-CRIN, INICRCT network, Paris, Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), and NephroTest Study Group: Marine Livrozet, Emmanuel Letavernier, Pierre Ronco, Hafedh Fessi, Emmanuelle Vidal-Petiot, Eric Daugas, Caroline du Halgouet, Renaud de La Faille, Gerard Maruani, Marion Vallet, Laurence Nicolet-Barousse, Alexandre Karras, Christian Jacquot
Subjects: Male, urine concentration ability, 030232 urology & nephrology, Urine osmolality, urologic and male genital diseases, tubular damage, 0302 clinical medicine, Risk Factors, 030212 general & internal medicine, Prospective Studies, prognostic factor, ComputingMilieux_MISCELLANEOUS, Fasting, Middle Aged, Prognosis, female genital diseases and pregnancy complications, 3. Good health, Survival Rate, Nephrology, Disease Progression, Biomarker (medicine), biomarker, Female, France, medicine.symptom, glomerular filtration rate (GFR), Cohort study, Glomerular Filtration Rate, medicine.medical_specialty, Urinary system, CKD progression, Urology, chronic kidney disease (CKD), 03 medical and health sciences, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Humans, Risk factor, Renal Insufficiency, Chronic, business.industry, Osmolar Concentration, medicine.disease, measured GFR (mGFR), Decreased glomerular filtration rate, end-stage renal disease (ESRD), Albuminuria, GFR decline, business, Biomarkers, Kidney disease
Abstract: International audience; Rationale & objective: Chronic kidney disease (CKD) characterized by decreased glomerular filtration rate (GFR) is often accompanied by various degrees of impaired tubular function in the cortex and medulla. Assessment of tubular function may therefore be useful in establishing the severity of kidney disease and identifying those at greater risk for CKD progression. We explored reductions in urinary concentrating ability, a well-known feature of CKD, as a risk factor for GFR decline and end-stage renal disease (ESRD).Study design: Prospective longitudinal cohort study.Setting & participants: 2,084 adult patients with CKD stages 1 to 4 from the French NephroTest Cohort Study.Predictor: Fasting urinary osmolality measured using delta cryoscopy.Outcomes: ESRD, mortality before ESRD, and measured GFR (mGFR) assessed using 51Cr-EDTA renal clearance.Analytical approach: Cause-specific hazards models were fit to estimate crude and adjusted associations of urinary osmolality with ESRD and death before ESRD. Linear mixed models with random intercepts were fit to evaluate the association of urinary osmolality with slope of decline in mGFR.Results: At baseline, mean age was 58.7±15.2 (SD) years with a median mGFR of 40.2 (IQR, 29.1-54.5) mL/min/1.73m2 and a median fasting urinary osmolality of 502.7±151.7mOsm/kg H2O. Baseline fasting urinary osmolality was strongly associated with mGFR (R=0.54; P < 0.001). 380 ESRD events and 225 deaths before ESRD occurred during a median follow-up of 5.9 (IQR, 3.8-8.2) years. Patients with lower baseline fasting urinary osmolality had higher adjusted risk for ESRD but not for mortality (HRs of 1.97 [95% CI, 1.26-3.08] and 0.99 [95% CI, 0.68-1.44], respectively, for the lowest vs highest tertile). Based on a mixed linear model adjusted for baseline mGFR and clinical characteristics, patients in the lowest tertile of baseline urinary osmolality had a steeper decline in kidney function (-4.9% ± 0.9% per year; P < 0.001) compared with patients in the highest tertile.Limitations: Fasting was self-reported.Conclusions: Fasting urinary osmolality may be a useful tool, in addition to GFR and albuminuria, for assessing nonglomerular damage in patients with CKD who are at higher risk for CKD progression.
Published: 2019

40. The European eel (Anguilla anguilla) in France: An Example of Close Cooperation Among Researchers and Fishers to Study and Manage an Endangered Species

Author: Patrick Prouzet, Nicolas Michelet, Catherine Boisneau, Eric Feunteun, Philippe Boisneau, Elsa Amilhat, Laboratoire Ressources Halieutiques Aquitaine IFREMER, Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), UMR 5110 CNRS-CEFREM, Université de Perpignan Via Domitia (UPVD), Cités, Territoires, Environnement et Sociétés (CITERES), Centre National de la Recherche Scientifique (CNRS)-Université de Tours (UT), Coordination Nationale de la Pêche Professionnelle en Eau Douce (CNAPPED), Laboratoire d'Evolution des Systèmes Naturels et Modifiés (LESNM), Muséum national d'Histoire naturelle (MNHN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Laboratoire Universitaire des Sciences Appliquées de Cherbourg (LUSAC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), Springer, Komatsu T., Ceccaldi HJ., Yoshida J., Prouzet P., Henocque Y., Centre National de la Recherche Scientifique (CNRS)-Université de Tours, Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), and Muséum national d'Histoire naturelle (MNHN)-Université de Rennes (UR)
Subjects: 0106 biological sciences, biology, 010604 marine biology & hydrobiology, Member states, [SDE.MCG]Environmental Sciences/Global Changes, Fishing, Endangered species, habitat, Silver eel, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, Fishery, Geography, Habitat, European eel, [SDE]Environmental Sciences, 14. Life underwater, population trend, Bay, Stock (geology), Escapement, ComputingMilieux_MISCELLANEOUS, management
Abstract: The European eel (Anguilla Anguilla) was a very valuable species for the economy of small scale fisheries in France both in marine and in inland waters. At the beginning of the 21st century the species was the third economical value of all the species caught in the Bay of Biscay despite a strong reduction in abundance since the middle of the 20th century and especially since the seventies. Right now, there is a sharp decline of the economic value of that fishery due to some constraining fishing regulations and due to the export ban of eel outside Europe. Due to a dramatic decrease of its abundance in all the European waters, the EU decided to implement an eel management plan in 2007, in a council regulation establishing measures for the recovery of the stock of the European eel. Each member states producing eels had to identify regulation measures and eel habitat and had to evaluate the effectiveness of these measures. They represented the basis of the national management plans defined by each member states that wish to exploit the eel resource. The objective of the eel national management plan is to reduce anthropogenic mortalities so as to permit with high probability the escapement to the sea of at least 40% of the silver eel biomass relative to the best estimate of escapement that would have existed if no anthropogenic influences had impacted the stock. In that context, some large scientific programs such as INDICANG and EELIAD have been undertaken to improve our present knowledge on the migratory behaviour of eel at different phases of its biological cycle, to develop some methodologies to evaluate the abundance of the stock in a given river system and to assess the relative effects of both fisheries and others anthropogenic factors on the future of the stock. A large part of these studies were undertaken through a close cooperation between scientists and fishers in order to add their know-how and knowledge to develop some technical approaches on the field. Some examples are given to illustrate these field experiments.
Published: 2019

41. Mandatory matching between microelectronics industry and higher education in engineering toward a digital society

Author: Olivier Bonnaud, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Minatec, Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), Uskov V., Howlett R., Jain L. (eds), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: Matching (statistics), Industry 4.0, Higher education, business.industry, Computer science, Higher education structuring, 4. Education, media_common.quotation_subject, 02 engineering and technology, 021001 nanoscience & nanotechnology, Engineering management, Presentation, [SPI]Engineering Sciences [physics], Embedded software, Engineering, Microelectronics, Multidisciplinary approach, 020204 information systems, 0202 electrical engineering, electronic engineering, information engineering, Software design, 0210 nano-technology, business, Communications protocol, media_common
Abstract: 6th International KES Conference on Smart Education and e-Learning, KES SEEL 2019 (2019-06-17 / 2019-06-19, St. Julian’s, Malte); International audience; The evolution of the world toward the digital society requires the development of many connected objects, the basis of the Internet of Things (IoT), with a very wide spectrum of applications. These connected objects are based on communication protocols, embedded software but more fundamentally on the hardware that corresponds to the physical realization of the objects. Microelectronic technologies are therefore at the heart of all these devices and systems. This exponential evolution is the result of more than 50 years of increasing integration, which is becoming very complex and combining many technological approaches and multidisciplinary architectures. The future industry 4.0 requires skills and competencies in microelectronic design and technological fabrication. At the same time, investments in manufacturing plants and design software follow the same exponential cost trend. To meet the needs of the industry, training must be constantly updated with good know-how on dedicated tools and equipment. To achieve this objective, higher education must be organized to provide students with knowledge and skills. A dedicated organization must be set up with common platforms that allow technological equipment and Computer-Aided-design tools (CAD) to be shared. This paper deals with the French national network which has proven its effectiveness in higher education in microelectronic engineering for more than thirty years. After a presentation of its organization and objectives, several examples of innovative practical work covering the different fields of application are given.
Published: 2019

42. Actions de vulgarisation du guichet national de formation continue du GIP-CNFM

Author: Olivier Bonnaud, Beatrice Pradarelli, Pascal Benoit, Pascal Nouet, Coordination Nationale de la Formation en Microélectronique (CNFM), Centre National de la Recherche Scientifique (CNRS), TEST (TEST), Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Smart Integrated Electronic Systems (SmartIES), and ADAptive Computing (ADAC)
Subjects: 0502 economics and business, 05 social sciences, Nanotechnologies, 050301 education, Visibilité, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, Formation continue, 0503 education, Microélectronique, 050203 business & management, Reconnaissance
Abstract: 15e journées pédagogiques du CNFM (Coordination nationale pour la formation en micro-électronique et en nanotechnologies); International audience; Cet article présente les actions de dissémination et de vulgarisation mises en œuvre pour promouvoir l’offre de formation continue en Microélectronique et en Nanotechnologies du réseau GIP-CNFM. Il rappelle la structuration et organisation du guichet d’entrée national et dresse le bilan 2014-2018 des formations continues réalisées dans le cadre du projet ANR IDEFI-FINMINA. Il conclut en adressant l’actualité et les nouvelles actions identifiées pour accroître la visibilité du GIP- CNFM dans le milieu de la formation professionnelle continue.
Published: 2019

43. L'évolution des technologies microélectroniques d'intégration et d'assemblage vers les IoT

Author: Bonnaud, Olivier, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: [SPI]Engineering Sciences [physics], [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2018

44. Know-how needs for higher education in nanoelectronics: French CNFM network strategy

Author: Bonnaud, Olivier, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: nanoelectronics, pedagogy, higher education, French national network, nanotechnologies, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics
Abstract: International audience; Microelectronic technologies have progressively shifted to nanotechnologies thanks to a permanent decrease in the size of elementary devices over the last 50 years. This evolution has been achieved by decreasing the lateral dimensions of the devices, and the thicknesses of the layers involved in the architecture of the devices. The minimum dimensions have today reached the size of several atoms. New concepts are introduced to better control the fabrication processes and, therefore, the electrical properties of circuits and systems. In parallel, the application spectrum of microelectronics has been broadened, which allows developing complete integrated systems such as connected objects, which also broadens the necessary skills of designers in a multidisciplinary manner. Research and industry therefore have a strong need for such skills and competences. As a consequence, Higher education must continuously adapt to meet these needs. This approach requires the existence of technological platforms, which are becoming more and more expensive due to the increasing complexity of the technology and which must be shared. In France, a national network was created and organized in this way. Based on several examples of the activities of the French common centers, this paper presents how to maintain a high scientific level and skills based on the knowledge and know-how of future engineers and researchers.
Published: 2018

45. Vaccin grippal quadrivalent : quels changements pour quels bénéfices ?

Author: Gaëtan Gavazzi, Claude Hannoun, Catherine Weil-Olivier, Odile Launay, Jacques Gaillat, Luc Martinez, Anne Mosnier, Laurence Josset, Pascal Crépey, Réseau des Groupes Régionaux d'Observation de la Grippe (GROG), Coordination nationale, CIC Cochin Pasteur (CIC 1417), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôtel-Dieu-Université Paris Descartes - Paris 5 (UPD5)-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire [Grenoble] (CHU), Laboratoire de Virologie [HCL, Lyon] (Institut des Agents Infectieux), Hospices civils de Lyon (HCL)-HCL Groupement Hospitalier Nord [Lyon]-Centre National de Reference des virus des Infections Respiratoires France Sud [HCL, Lyon], École des Hautes Études en Santé Publique [EHESP] (EHESP), Recherche en Pharmaco-épidémiologie et Recours aux Soins (REPERES), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP), Université Paris Diderot - Paris 7 (UPD7), Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois], Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP), and Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Cochin [AP-HP]-Hôtel-Dieu-Université Paris Descartes - Paris 5 (UPD5)-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale (INSERM)
Subjects: business.industry, Lineage (evolution), General Medicine, Virus diseases, Vaccine efficacy, medicine.disease_cause, Virology, Vaccin grippal quadrivalent, Virus, 3. Good health, Vaccin anti grippal, 03 medical and health sciences, 0302 clinical medicine, Vaccine strain, Antigen, Immunization, 030225 pediatrics, Influenza A virus, Medicine, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, 030212 general & internal medicine, business
Abstract: International audience; Currently, circulating viruses responsible for annual seasonal influenza epidemics belong to two influenza A subtypes, A(H1N1) and A(H3N2), and to two antigenically distinct type B lineages, B/Yamagata and B/Victoria lineages. Like diseases due to influenza A virus, influenza B virus diseases may have severe consequences and should be prevented. Until now, in France, the vaccines used to prevent seasonal influenza were trivalent, systematically targeting viruses belonging to both A subtypes and to one or other of the B lineages. The protective efficacy of trivalent vaccines is diminished during the seasons when viruses belonging to both B lineages cocirculated or when the circulating dominant type B virus belonged to a lineage different from that targeted by the vaccine strain. By targeting viruses belonging to both B lineages, quadrivalent vaccines improve the antigenic concordance between circulating and vaccine type B strains. Three inactivated quadrivalent vaccines are authorized for marketing in France and should be available for the 2018-2019 season. It is expected that, by providing enlarged protection, these quadrivalent influenza vaccines will improve vaccine efficacy, the confidence in immunization of the public, the satisfaction of health professionals, and ultimately will help to complete immunization coverage.
Published: 2018

46. Increasing Attractiveness of Electrical Engineering for Schoolers Through Experiments on Microelectronics and Nanotechnology Interuniversity Platforms

Author: Robert Baptist, Olivier Bonnaud, Skandar Basrour, Ahmad Bsiesy, Etienne Pernot, Eric Martinet, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), Centre Interuniversitaire de Micro-Electronique (CIME), Institut National Polytechnique de Grenoble (INPG), Techniques de l'Informatique et de la Microélectronique pour l'Architecture des systèmes intégrés (TIMA), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire des matériaux et du génie physique (LMGP ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Institut d'Electronique et de Télécommunications de Rennes (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), CIME Nanotech G-INP UJF (CIME), Techniques of Informatics and Microelectronics for integrated systems Architecture (TIMA), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Laboratoire des matériaux et du génie physique (LMGP), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP), ANR-11-IDFI-0017,FINMINA,Formation Innovante en Microélectronique et Nanotechnologies, Institut National Polytechnique de Grenoble (INPG)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Nantes Université (NU)-Université de Rennes 1 (UR1)
Subjects: Attractiveness, Engineering, Higher education, business.industry, 4. Education, media_common.quotation_subject, 05 social sciences, Electrical engineering, 050301 education, Nanotechnology, Context (language use), Field (computer science), Presentation, [SPI]Engineering Sciences [physics], 0502 economics and business, Microelectronics, Electronics, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, business, Set (psychology), 0503 education, 050203 business & management, ComputingMilieux_MISCELLANEOUS, media_common
Abstract: The world is witnessing a new industrial revolution, which is the generation 4.0 of the industry and many jobs will be related to the development, production and use of connected objects. Thus, the field of microelectronics, at the heart of these objects, increasingly needs specialists. Unfortunately, young people are less and less attracted to science, electrical engineering and microelectronics. The French Higher Education Network in Microelectronics and Nanotechnology, which includes twelve interuniversity centers, is financially supported by a national project on innovation that contains a work-package devoted to raising awareness among high-schoolers. In this way, classes of high-schoolers can experience the fabrication, design and characterization of electronic devices. In 2011, the Grenoble center started hosting secondary classes for a one-day course on its platforms. This activity made it necessary to adapt the training content. To this end, recent practical training courses have been set up. After a presentation of the context of microelectronics, the document deals with the organization and presentation of the practical training dedicated to schools on the platforms of higher education. The effectiveness of this experiment will then be discussed. As a main result, this approach has been extended to other centers in the national network.
Published: 2018

47. (Invited) Thin Film Transistor Technologies: Implementing Research Results in Higher Education to Prepare the Emerging Multidisciplinary Connected Objects

Author: Olivier Bonnaud, Ahmad Bsiesy, Laurent Pichon, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), Centre Interuniversitaire de Micro-Electronique (CIME), Institut National Polytechnique de Grenoble (INPG), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), CIME Nanotech G-INP UJF (CIME), and Université de Nantes (UN)-Université de Rennes 1 (UR1)
Subjects: 010302 applied physics, Engineering, Higher education, business.industry, 02 engineering and technology, 021001 nanoscience & nanotechnology, 7. Clean energy, 01 natural sciences, Engineering physics, Thin-film transistor, Multidisciplinary approach, 0103 physical sciences, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, 0210 nano-technology, business
Abstract: Thin film technologies, particularly thin-film transistors, have been the backbone of large-area electronics for decades, primarily for display applications such as flat panel displays. These devices were mainly manufactured on glass substrate. The processes have therefore been considered as a low temperature technology compared to bulk silicon CMOS technology processes. However, due to the huge development of integrated electronics in parallel driven by a steady size reduction to cope with Moore’s law, the CMOS thermal budget has been drastically lowered, which in-fine brought both technologies to comparable processing temperatures. Today, flexible plastics is used as a substrate. In addition, as the physical limitation of dimensions becomes close to the size of one monolayer, integration has shifted to the third dimension by stacking circuit substrates and other physical or electrical functions (more than Moore). As a result, electrical circuits become three-dimensional and increasingly involve thin-film technologies in new systems-on-a-chip (SOC) or systems-in-package (SiP). This trend allows creating new objects that are gathering several functions with communication capabilities, i.e. connected smart objects. The connected objects can contain sensors, actuators, signal processing circuits but also displays, energy harvesting device. In other words, they combine large area electronics and CMOS ones. The main advantage of the thin film technologies is also offering the possibilities to process multidisciplinary objects such as MEMS (micro-electrical-mechanical systems), BioMEMS for biological application, Optoelectronic systems, for example. The spectrum of combination is increasingly wider and hence addresses a large field of applications to many societal issues such as health, environment, security, transport, energy, communications, etc. The research activities for the development of thin film transistors technologies is mature even if progress still remain to reduce the power consumption and/or to improve the electrical characteristics, the sensitivity and the reliability. Important research efforts were devoted to improve the quality of the semiconductor materials, to adapt the thin layer deposition techniques to the nature of the substrate, to improve the interfaces at the border of the active zones, to minimize the density of defects despite a low temperature budget by involving several techniques of crystallization and/or depositions, by and also changing the architecture of the elementary device, and the design of the circuits, …. A large variety of skills has to be made available in order to keep the pace of this technology development. This means the training of skilled technicians, engineers, and researchers bearing PhD degrees. In a context of digital society, developing the skills of the graduate students is strongly linked to the knowledge and the associated know-how. The initial education of engineers and researchers must contain several practical training based on the outcome of research activity allowing an awareness of the students to the new challenge. Practical training to develop advanced know-how skills might be hindered by the cost of the equipment and the associated running expenses. To meet this challenge, the French CNFM (National coordination for Education in Microelectronics and Nanotechnologies) network strategy is sharing the fabrication facilities such as the cleanroom and the design tools. In this strategy, twelve microelectronics centers were created in the early 80’s, seven of them having cleanrooms opened to initial education, and lifelong learning. Today, these centers are organized in a network, recognized by the Ministry of Higher Education that financially supports at least partially, the common activities. In this network two important industrial partners are members of the CNFM BoD. Several CNFM centers have activities in the thin film technologies, mainly Rennes, Grenoble, Lille and Bordeaux centers. They have developed practicals for students that include amorphous and polycrystalline silicon thin film transistors technologies, and more recently organic semiconductors for photovoltaic and optoelectronics applications, graphene thin film devices, or insulator ultrathin films for memories (such as Metal-Insulator-Metal or MIM), but also sensors and actuators involving suspended gate thin film transistors, suspended membranes, nanowires or cantilevers, piezoelectric films, etc. After a presentation of the evolution of the thin film technologies thanks to the research activities, and of the societal issues for applications that include the development of connected objects, the presentation highlights the set-up of training covering the different aspects of the thin film technologies in order to train the graduate students for the future digital and connected society. This transfer from the research activities towards the Higher Education is the main mission of the University world.
Published: 2018

48. Innovation for education on Internet of things

Author: Bonnaud, Olivier, Fesquet, Laurent, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), Techniques de l'Informatique et de la Microélectronique pour l'Architecture des systèmes intégrés (TIMA), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), CIME Nanotech G-INP UJF (CIME), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Institut d'Electronique et de Télécommunications de Rennes (IETR), Université de Nantes (UN)-Université de Rennes 1 (UR1), Techniques of Informatics and Microelectronics for integrated systems Architecture (TIMA), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), ANR-11-IDFI-0017,FINMINA,Formation Innovante en Microélectronique et Nanotechnologies, Bidégaray-Fesquet, Brigitte, Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique - - FINMINA2011 - ANR-11-IDFI-0017 - IDFI - VALID, Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Centre Interuniversitaire de Micro-Electronique (CIME), and Institut National Polytechnique de Grenoble (INPG)
Subjects: education, lcsh:T, [SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, microelectronics, nanotechnologies, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, internet of things, lcsh:Technology, innovation, ComputingMilieux_MISCELLANEOUS
Abstract: The Internet of Things (IoT) and related objects are becoming more prevalent around the world with exponential growth for the next fifteen years. This evolution implies innovation in many fields of technology, whose core is in microelectronics. Indeed, IoT deals with all societal applications such as health, the environment, transport, energy and communications. Thus, connected objects involve many technological components: sensors and actuators, signal processing circuits, data transmission circuits and systems, energy recovery systems, which directly depend on the performance of microelectronics. To create new connected objects, innovation is the main driver. Innovation results from the combination of a multidisciplinary approach, links between disciplines and the necessary know-how of engineers and technicians. This paper deals with the orientation of pedagogy towards these objectives through the development of dedicated and innovative platforms in microelectronics. These platforms are developed by the French National Microelectronics Education Network (CNFM). After presenting the context of IoT and the evolution of microelectronics technologies, this article highlights the main components of connected objects applied to many societal applications. Each component of the objects requires specific microelectronic devices or circuits. Innovation appears in the nature of platforms, the multidisciplinary approach of training, the permanent links between disciplines, and the adaptation to new educational tools, mainly online. The results of the training on innovative platforms are presented and discussed.
Published: 2018

49. Microélectronique et société connectée : formation au savoir-faire du réseau CNFM

Author: Bonnaud, Olivier, Institut d'Électronique et des Technologies du numéRique (IETR), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Université de Nantes (UN)-Université de Rennes 1 (UR1), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
Subjects: [SPI]Engineering Sciences [physics], [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, ComputingMilieux_MISCELLANEOUS
Abstract: National audience
Published: 2018

50. New Vision in Microelectronics Education: Smart e-Learning and Know-How, A Complementary Approach

Author: Olivier Bonnaud, Institut d'Électronique et des Technologies du numéRique (IETR), Université de Nantes (UN)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Coordination Nationale pour la Formation en Microélectronique et en nanotechnologies (GIP-CNFM), ANR-11-IDFI-0017,FINMINA,Réseau national pour les Formations INnovantes en MIcro et Nanoélectronique(2011), Nantes Université (NU)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), ANR-11-IDFI-0017, MOHE, Ministry of Higher Education, Howlett R.J.Uskov V.L.Vlacic L.Jain L.C., and Université de Nantes (UN)-Université de Rennes 1 (UR1)
Subjects: New approaches, Engineering learning, Cover (telecommunications), Computer science, media_common.quotation_subject, E-learning (theory), Complex networks, Context (language use), 02 engineering and technology, E-learning, [SPI]Engineering Sciences [physics], Presentation, Microelectronics, Digital society, 020204 information systems, 0202 electrical engineering, electronic engineering, information engineering, [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics, Set (psychology), ComputingMilieux_MISCELLANEOUS, Technology transfer, Connected objects, On-line tools, media_common, business.industry, 05 social sciences, Manufacture, Practical training, 050301 education, Data science, business, Microelectronics training, 0503 education, Know-how
Abstract: International audience; The evolution towards a digital society is indisputable and the development of online tools adapted to education is becoming a priority. At the same time, the technologies that allow the development of these tools as well as the connected objects become more and more complex with a need for know-how as well for the design of these objects as for their manufacture and production. Let us mention that the connected objects cover a large spectrum of applications opened to other disciplines. A new approach to education is needed. Following a presentation of the context, this article discusses the strategy that has been adopted to successfully combine engineering learning, and more especially the microelectronics training with the e-learning and the acquisition of know-how through practice. Because practical training is becoming more and more complex and costly, the trend is to share platforms dedicated to education within the framework of a network. This was set up in France for more than thirty years. The evolution of this network in this new context of digital society with an increasing priority of development of Internet of Things is presented and discussed. © 2019, Springer International Publishing AG, part of Springer Nature.
Published: 2018

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