153 results on '"Cooper, Cushla"'
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2. The Oxford Finger Nail Appearance Score - a new scoring system for fingernail deformity following paediatric finger tip trauma
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Jain, Abhilash, Stokes, Jamie, Gardiner, Matthew D., Cook, Jonathan A., Jones, Amy, Cooper, Cushla, Shirkey, Beverly, Sierakowski, Adam, Beard, David, Greig, Aina V.H., Dupré, Sophie, Adami, Raina Zarb, Baker, Benjamin, Fleet, Malik, Miles, Debbie, Nicholas, Rebecca, Nicola, Alexi, Plonczak, Agata, Sleiwah, Aseel, and Williams, Georgina
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- 2021
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3. Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS‐CoV‐2.
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Higham, Helen E., Morgan, Lauren, Cooper, Cushla, Marshall, Julia, Mawer, Andrew, Jackson, Susan, Lopez‐Ramon, Raquel, Hughes, Eileen, Richards, Duncan, McShane, Helen, and Fullerton, James N.
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EXPERIMENTAL medicine ,SARS-CoV-2 ,INFECTION control ,PILOT projects ,SAFETY factor in engineering - Abstract
Aims: The influence of human factors on safety in healthcare settings is well established, with targeted interventions reducing risk and enhancing team performance. In experimental and early phase clinical research participant safety is paramount and safeguarded by guidelines, protocolized care and staff training; however, the real‐world interaction and implementation of these risk‐mitigating measures has never been subjected to formal system‐based assessment. Methods: Independent structured observations, systematic review of study documents, and interviews and focus groups were used to collate data on three key tasks undertaken in a clinical research facility (CRF) during a SARS CoV‐2 controlled human infection model (CHIM) study. The Systems Engineering Initiative for Patient Safety (SEIPS) was employed to analyse and categorize findings, and develop recommendations for safety interventions. Results: High levels of team functioning and a clear focus on participant safety were evident throughout the study. Despite this, latent risks in both study‐specific and CRF work systems were identified in all four SEIPS domains (people, environment, tasks and tools). Fourteen actionable recommendations were generated collaboratively. These included inter‐organization and inter‐study standardization, optimized checklists for safety critical tasks, and use of simulation for team training and exploration of work systems. Conclusions: This pioneering application of human factors techniques to analyse work systems during the conduct of research in a CRF revealed risks unidentified by routine review and appraisal, and despite international guideline adherence. SEIPS may aid categorization of system problems and the formulation of recommendations that reduce risk and mitigate potential harm applicable across a trials portfolio. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Findings from the patch augmented rotator cuff surgery (PARCS) feasibility study
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Cook, Jonathan A., Baldwin, Mathew, Cooper, Cushla, Nagra, Navraj S., Crocker, Joanna C., Glaze, Molly, Greenall, Gemma, Rangan, Amar, Kottam, Lucksy, Rees, Jonathan L., Farrar-Hockley, Dair, Merritt, Naomi, Hopewell, Sally, Beard, David, Thomas, Michael, Dritsaki, Melina, and Carr, Andrew J.
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- 2021
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5. Correction to: Reamed intramedullary nailing versus circular frame external fixation for segmental tibial fractures (STIFF-F): a mixed methods feasibility study
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Hing, Caroline B., Tutton, Elizabeth, Smith, Toby O., Glaze, Molly, Stokes, Jamie R., Cook, Jonathan, Dritsaki, Melina, Phelps, Emma, Cooper, Cushla, Trompeter, Alex, Pearse, Michael, Law, Michael, and Costa, Matthew L.
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- 2021
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6. The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
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Rogers, Chris A., Andrews, Robert, Blazeby, Jane M., Byrne, James, Donovan, Jenny L., Kelly, Jamie, Mazza, Graziella, Mahon, David, Noble, Hamish, Reeves, Barnaby C., Thompson, Janice L., Wordsworth, Sarah, Welbourn, Richard, Beard, David, Carr, Andrew, Cook, Jonathan, Cooper, Cushla, Dean, Benjamin, Gray, Alastair, Gwilym, Stephen, Judge, Andrew, Merritt, Naomi, Moser, Jane, Rees, Jonathan, Rombach, Ines, Savulescu, Julian, Tracey, Irene, Wartolowska, Karolina, Harrison, Eleanor, Tan, Wei, Mills, Nicola, Karantana, Alexia, Sprange, Kirsty, Duley, Lelia, Elliott, Daisy, Hollingworth, William, Montgomery, Alan A., Davis, Tim, Stein, Rob, Bartlett, John, Cameron, David, Campbell, Amy, Canney, Peter, Dunn, Janet, Earl, Helena, Falzon, Mary, Francis, Adele, Hall, Peter, Harmer, Victoria, Higgins, Helen, Hiller, Louise, Hughes-Davies, Luke, Hulme, Claire, Macpherson, Iain, Makris, Andreas, Marshall, Andrea, McCabe, Christopher, Morgan, Adrienne, Pinder, Sarah, Poole, Christopher, Provenzano, Elena, Rea, Daniel, Stallard, Nigel, Avery, Kerry N.L., Barham, C. Paul, Berrisford, Richard, Elliott, Jackie, Falk, Stephen J., Goldin, Rob, Hanna, George, Hollowood, Andrew A., Krysztopik, Richard, Metcalfe, Chris, Noble, Sian, Sanders, Grant, Streets, Christopher G., Titcomb, Dan R., Wheatley, Tim, Rooshenas, Leila, Scott, Lauren J., Tilling, Kate M., Husbands, Samantha, Conefrey, Carmel, Stein, Robert C., Carr, Andrew J., Beard, David J., Paramasivan, Sangeetha, Jepson, Marcus, Avery, Kerry, and Wilson, Caroline
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- 2019
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7. Findings from a pilot randomized trial of spinal decompression alone or spinal decompression plus instrumented fusion
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Beresford-Cleary, Nicolas J. A., primary, Silman, Alan, additional, Thakar, Chrishan, additional, Gardner, Adrian, additional, Harding, Ian, additional, Cooper, Cushla, additional, Cook, Jonathan, additional, and Rothenfluh, Dominique A., additional
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- 2023
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8. Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2
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Higham, Helen, primary, Morgan, Lauren, additional, Cooper, Cushla, additional, Marshall, Julia, additional, Mawer, Andrew, additional, Jackson, Susan, additional, Lopez-Ramon, Raquel, additional, Hughes, Eileen, additional, Richards, Duncan, additional, McShane, Helen, additional, and Fullerton, James, additional
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- 2023
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9. An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
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Beard, David, Carr, Andrew, Cook, Jonathan, Cooper, Cushla, Dean, Benjamin, Donovan, Jenny L., Gray, Alastair, Gwilym, Stephen, Judge, Andrew, Merritt, Naomi, Moser, Jane, Rees, Jonathan, Rombach, Ines, Savulescu, Julian, Tracey, Irene, Wartolowska, Karolina, Blazeby, Jane M., Barham, Paul, Brookes, Sara T., Crosby, Tom, Falk, Stephen J., Griffin, S. Michael, Hollingworth, William, Hollowood, Andrew D., Krysztopik, Richard, Lewis, Wyn, Nicklin, Jo, Streets, Christopher, Strong, Sean, Titcomb, Dan, Williams, Geraint, Birtle, Alison, Bryan, Rik, Catto, James, Chester, John, French, Ann, Hall, Emma, Harris, Chris, Johnson, Mark, Jones, Rob, Keeley, Francis, Kirkbank, Tony, Kockelbergh, Roger, Lewis, Rebecca, Newton, Michelle, Powles, Thomas, Waters, Rachel, Winterbottom, Andrew, Halliday, Alison, Becquemin, Jean-Pierre, Belli, Anna, Bosiers, Marc, Cao, Piergiorgio, Davies, Christina, Gough, Michael, Hayter, Elizabeth, Leopold, Peter, McDonald, Sumaira, Michaels, Jonathan, Mihaylova, Borislava, Peto, Richard, Robertson, Steven, Rothwell, Peter, Scott, Rachael, Thomas, Dafydd, Vermassen, Frank, Stein, Rob, Bartlett, John, Cameron, David, Campbell, Amy, Canney, Peter, Dunn, Janet, Earl, Helena, Falzon, Mary, Francis, Adele, Hall, Peter, Harmer, Victoria, Higgins, Helen, Hiller, Louise, Hughes-Davies, Luke, Hulme, Claire, Macpherson, Iain, Makris, Andreas, Marshall, Andrea, McCabe, Christopher, Morgan, Adrienne, Pinder, Sarah, Poole, Christopher, Rea, Daniel, Stallard, Nigel, Jepson, Marcus, Elliott, Daisy, Conefrey, Carmel, Wade, Julia, Rooshenas, Leila, and Wilson, Caroline
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- 2018
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10. Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
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Ahrens, Philip, Baldwick, Cheryl, Brinsden, Mark, Brownlow, Harry, Burton, David, Butt, Muhammad Sohail, Carr, Andrew, Charalambous, Charalambos P, Conboy, Veronica, Dennell, Lucy, Donaldson, Oliver, Drew, Steven, Dwyer, Amitabh, Gidden, David, Hallam, Peter, Kalogrianitis, Socrates, Kelly, Cormac, Kulkarni, Rohit, Matthews, Tim, McBirnie, Julie, Patel, Vipul, Peach, Chris, Roberts, Chris, Robinson, David, Rosell, Philip, Rossouw, Dan, Senior, Colin, Singh, Bijayendra, Sjolin, Soren, Taylor, Geoffrey, Venkateswaran, Balachandran, Woods, David, Beard, David J, Rees, Jonathan L, Cook, Jonathan A, Rombach, Ines, Cooper, Cushla, Merritt, Naomi, Shirkey, Beverly A, Donovan, Jenny L, Gwilym, Stephen, Savulescu, Julian, Moser, Jane, Gray, Alastair, Jepson, Marcus, Tracey, Irene, Judge, Andrew, Wartolowska, Karolina, and Carr, Andrew J
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- 2018
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11. Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): study protocol for a patient-blinded, randomised controlled superiority trial of liposomal bupivacaine
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Knight, Ruth, Poulton, Lisa, Strickland, Louise H., Hamilton, Thomas W., Beard, David, Cook, Jonathan, Dutton, Susan J., Leal, Jose, Lamb, Sarah, Cooper, Cushla, Barker, Karen L., Murray, David W., and Pandit, Hemant G.
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- 2019
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12. Effectiveness of nail bed repair in children with or without replacing the fingernail: NINJA multicentre randomized clinical trial.
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Jain, Abhilash, Greig, Aina V. H., Jones, Amy, Cooper, Cushla, Davies, Loretta, Greshon, Akiko, Fletcher, Heidi, Sierakowski, Adam, Dritsaki, Melina, Thi Thu An Nguyen, May Ee Png, Stokes, Jamie R., Dakin, Helen, Cook, Jonathan A., Beard, David J., and Gardiner, Matthew D.
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FINGERNAILS ,NAILS (Anatomy) ,PLASTIC surgery ,CLINICAL trials ,MEDICAL care costs ,ARM exercises - Abstract
Background: Surgery for nail bed injuries in children is common. One of the key surgical decisions is whether to replace the nail plate following nail bed repair. The aim of this RCT was to assess the clinical effectiveness and cost-effectiveness of nail bed repair with fingernail replacement/substitution compared with repair without fingernail replacement. Methods: A two-arm 1 : 1 parallel-group open multicentre superiority RCT was performed across 20 secondary-care hospitals in the UK. The co-primary outcomes were surgical-site infection at around 7 days after surgery and cosmetic appearance summary score at a minimum of 4 months. Results: Some 451 children presenting with a suspected nail bed injury were recruited between July 2018 and July 2019; 224 were allocated to the nail-discarded arm, and 227 to the nail-replaced arm. There was no difference in the number of surgical-site infections at around 7 days between the two interventions or in cosmetic appearance. The mean total healthcare cost over the 4 months after surgery was €84 (95 per cent c.i. 34 to 140) lower for the nail-discarded arm than the nail-replaced arm (P < 0.001). Conclusion: After nail bed repair, discarding the fingernail was associated with similar rates of infection and cosmesis ratings as replacement of the finger nail, but was cost saving. Registration number: ISRCTN44551796 (http://www.controlled-trials.com). [ABSTRACT FROM AUTHOR]
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- 2023
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13. Methodological challenges and pragmatic design in randomised controlled trials comparing surgery and rehabilitation
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Gupta, Vandana Ayyar, Palmer, Antony, Rombach, Ines, Dutton, Susan, Cooper, Cushla, Barker, Karen, Beard, David, and Glyn-Jones, Sion
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- 2015
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14. Recruitment challenges in physiotherapy trials
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Gandhi, Varsha, Cooper, Cushla, and Barker, Karen
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- 2015
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15. Efficacy of Liposomal Bupivacaine and Bupivacaine Hydrochloride vs Bupivacaine Hydrochloride Alone as a Periarticular Anesthetic for Patients Undergoing Knee Replacement: A Randomized Clinical Trial.
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Hamilton, Thomas W., Knight, Ruth, Stokes, Jamie R., Rombach, Ines, Cooper, Cushla, Davies, Loretta, Dutton, Susan J., Barker, Karen L., Cook, Jonathan, Lamb, Sarah E., Murray, David W., Poulton, Lisa, Wang, Ariel, Strickland, Louise H., Van Duren, Bernard H., Leal, Jose, Beard, David, Pandit, Hemant G., and Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK) Study Group
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- 2022
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16. Reamed intramedullary nailing versus circular frame external fixation for segmental tibial fractures (STIFF-F): a mixed methods feasibility study
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Hing, Caroline B., primary, Tutton, Elizabeth, additional, Smith, Toby O., additional, Glaze, Molly, additional, Stokes, Jamie R., additional, Cook, Jonathan, additional, Dritsaki, Melina, additional, Phelps, Emma, additional, Cooper, Cushla, additional, Trompeter, Alex, additional, Pearse, Michael, additional, Law, Michael, additional, and Costa, Matthew L., additional
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- 2021
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17. Findings from the Patch Augmented Rotator Cuff Surgery (PARCS) Feasibility Study
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Cook, Jonathan Alistair, primary, Baldwin, Mathew, additional, Cooper, Cushla, additional, Nagra, Navraj S., additional, Crocker, Joanna C., additional, Glaze, Molly, additional, Greenall, Gemma, additional, Rangan, Amar, additional, Kottam, Lucksy, additional, Rees, Jonathan L., additional, Farrar-Hockley, Dair, additional, Merritt, Naomi, additional, Hopewell, Sally, additional, Beard, David, additional, Thomas, Michael, additional, Dritsaki, Melina, additional, and Carr, Andrew J., additional
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- 2021
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18. Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
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Voysey, Merryn, primary, Costa Clemens, Sue Ann, additional, Madhi, Shabir A, additional, Weckx, Lily Y, additional, Folegatti, Pedro M, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Baillie, Vicky L, additional, Barnabas, Shaun L, additional, Bhorat, Qasim E, additional, Bibi, Sagida, additional, Briner, Carmen, additional, Cicconi, Paola, additional, Clutterbuck, Elizabeth A, additional, Collins, Andrea M, additional, Cutland, Clare L, additional, Darton, Thomas C, additional, Dheda, Keertan, additional, Dold, Christina, additional, Duncan, Christopher J A, additional, Emary, Katherine R W, additional, Ewer, Katie J, additional, Flaxman, Amy, additional, Fairlie, Lee, additional, Faust, Saul N, additional, Feng, Shuo, additional, Ferreira, Daniela M, additional, Finn, Adam, additional, Galiza, Eva, additional, Goodman, Anna L, additional, Green, Catherine M, additional, Green, Christopher A, additional, Greenland, Melanie, additional, Hill, Catherine, additional, Hill, Helen C, additional, Hirsch, Ian, additional, Izu, Alane, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kerridge, Simon, additional, Koen, Anthonet, additional, Kwatra, Gaurav, additional, Lazarus, Rajeka, additional, Libri, Vincenzo, additional, Lillie, Patrick J, additional, Marchevsky, Natalie G, additional, Marshall, Richard P, additional, Mendes, Ana V A, additional, Milan, Eveline P, additional, Minassian, Angela M, additional, McGregor, Alastair, additional, Mujadidi, Yama F, additional, Nana, Anusha, additional, Padayachee, Sherman D, additional, Phillips, Daniel J, additional, Pittella, Ana, additional, Plested, Emma, additional, Pollock, Katrina M, additional, Ramasamy, Maheshi N, additional, Ritchie, Adam J, additional, Robinson, Hannah, additional, Schwarzbold, Alexandre V, additional, Smith, Andrew, additional, Song, Rinn, additional, Snape, Matthew D, additional, Sprinz, Eduardo, additional, Sutherland, Rebecca K, additional, Thomson, Emma C, additional, Török, M Estée, additional, Toshner, Mark, additional, Turner, David P J, additional, Vekemans, Johan, additional, Villafana, Tonya L, additional, White, Thomas, additional, Williams, Christopher J, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Pollard, Andrew J, additional, Aban, Marites, additional, Abeyskera, Kushala W.M., additional, Aboagye, Jeremy, additional, Adam, Matthew, additional, Adams, Kirsty, additional, Adamson, James P., additional, Adewatan, Gbadebo, additional, Adlou, Syed, additional, Ahmed, Khatija, additional, Akhalwaya, Yasmeen, additional, Akhalwaya, Saajida, additional, Alcock, Andrew, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Alvernaz, Felipe B., additional, Amorim, Fabio Santos, additional, Andrade, Claudia Sala, additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Arbe-Barnes, Edward H., additional, Ariaans, Mark P., additional, Arns, Beatriz, additional, Arruda, Laiana, additional, Assad, Luiza, additional, Azi, Paula De Almeida, additional, Azi, Lorena De Almeida, additional, Babbage, Gavin, additional, Bailey, Catherine, additional, Baker, Kenneth F., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baleanu, Ioana, additional, Bandeira, Danieli, additional, Bara, Anna, additional, Barbosa, Marcella A.S., additional, Barker, Debbie, additional, Barlow, Gavin D., additional, Barnes, Eleanor, additional, Barr, Andrew S., additional, Barrett, Jordan R., additional, Barrett, Jessica, additional, Barrett, Kelly, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beales, Emily, additional, Beckley, Rebecca, additional, Belij-Rammerstorfer, Sandra, additional, Bell, Jonathan, additional, Bellamy, Duncan, additional, Belton, Sue, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Berry, Lisa, additional, Berzenyi, Daniella, additional, Beveridge, Amy, additional, Bewley, Kevin R., additional, Bharaj, Inderjeet, additional, Bhikha, Sutika, additional, Bhorat, Asad E., additional, Bhorat, Zaheda E., additional, Bijker, Else Margreet, additional, Birch, Sarah, additional, Birch, Gurpreet, additional, Birchall, Kathryn, additional, Bird, Adam, additional, Bird, Olivia, additional, Bisnauthsing, Karen, additional, Bittaye, Mustapha, additional, Blackwell, Luke, additional, Blacow, Rachel, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bodalia, Pritesh, additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Bradley, Penny, additional, Brenner, Tanja, additional, Bridges-Webb, Alice, additional, Brown, Phillip, additional, Brown, Claire, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Budd, William, additional, Bulbulia, Yusuf A., additional, Bull, Melanie, additional, Burbage, Jamie, additional, Burn, Aileen, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabrera Puig, Ingrid, additional, Calvert, Anna, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Cardona, Rita, additional, Cardoso, João R., additional, Carr, Melanie, additional, Carroll, Miles W., additional, Carson-Stevens, Andrew, additional, Carvalho, Yasmin de M., additional, Casey, Helen R., additional, Cashen, Paul, additional, Castro, Thais R.Y., additional, Castro, Lucia Carratala, additional, Cathie, Katrina, additional, Cavey, Ana, additional, Cerbino-Neto, José, additional, Cezar, Luiz Fernando F., additional, Chadwick, Jim, additional, Chanice, Chanice, additional, Chapman, David, additional, Charlton, Sue, additional, Cheliotis, Katerina S., additional, Chelysheva, Irina, additional, Chester, Oliver, additional, Chiplin, Emily, additional, Chita, Sunder, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Clark, Matthew, additional, Colin-Jones, Rachel, additional, Collins, Sarah L.K., additional, Colton, Hayley, additional, Conlon, Christopher P., additional, Connarty, Sean, additional, Coombes, Naomi, additional, Cooper, Cushla, additional, Cooper, Rachel, additional, Cornelissen, Lynne, additional, Corrah, Tumena, additional, Cosgrove, Catherine A., additional, Costa, Fernanda Barroso, additional, Cox, Tony, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Dan, additional, Cunha, Debora R.M.F., additional, Cunningham, Christina J., additional, Cuthbertson, Fiona C., additional, da Costa, Daniel Marinho, additional, Da Guarda, Suzete N. Farias, additional, da Silva, Larissa P., additional, da Silva Moraes, Antonio Carlos, additional, Damratoski, Brad E., additional, Danos, Zsofia, additional, Dantas, Maria T.D.C., additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davids, Malika, additional, Davies, Sarah L., additional, Davies, Kelly, additional, Davies, Hannah, additional, Davies, Sophie, additional, Davies, Judith, additional, Davis, Elizabeth J., additional, Davis, John, additional, de Carvalho, José A.M., additional, De Jager, Jeanne, additional, de Jesus Jnr, Sergio, additional, De Oliveira Kalid, Lis Moreno, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Desai, Amisha, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, Dinesh, Tanya, additional, Docksey, Claire, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Dos Santos, Tannyth Gomes, additional, Dos Santos, Thainá G., additional, Dos Santos, Erika Pachecho, additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Drury, Ruth, additional, Du Plessis, Joan, additional, Dunachie, Susanna J., additional, Duncan, Andrew, additional, Easom, Nicholas J.W., additional, Edwards, Mandy, additional, Edwards, Nick J., additional, Edwards, Frances, additional, El Muhanna, Omar M., additional, Elias, Sean C., additional, Ellison-Handley, Branwen, additional, Elmore, Michael J., additional, English, Marcus Rex, additional, Esmail, Alisgair, additional, Essack, Yakub Moosa, additional, Farooq, Mutjaba, additional, Fedosyuk, Sofiya, additional, Felle, Sally, additional, Ferguson, Susie, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Fletcher, James, additional, Fofie, Hazel, additional, Fok, Henry, additional, Ford, Karen J., additional, Fothergill, Ross, additional, Fowler, Jamie, additional, Fraiman, Pedro H.A., additional, Francis, Emma, additional, Franco, Marilia M., additional, Frater, John, additional, Freire, Marilúcia S.M., additional, Fry, Samantha H., additional, Fudge, Sabrina, additional, Furlan Filho, Renato, additional, Furze, Julie, additional, Fuskova, Michelle, additional, Galian-Rubio, Pablo, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Gibbons, Karyna A., additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Godwin, Kerry, additional, Gokani, Karishma, additional, Gonçalves, Maria Luisa Freire, additional, Gonzalez, Isabela G.S., additional, Goodall, Jack, additional, Goodwin, Jayne, additional, Goondiwala, Amina, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Goyanna, Alvaro, additional, Grab, Janet, additional, Gracie, Lara, additional, Green, Justin, additional, Greenwood, Nicola, additional, Greffrath, Johann, additional, Groenewald, Marisa M., additional, Gunawardene, Anishka, additional, Gupta, Gaurav, additional, Hackett, Mark, additional, Hallis, Bassam, additional, Hamaluba, Mainga, additional, Hamilton, Elizabeth, additional, Hamlyn, Joseph, additional, Hammersley, Daniel, additional, Hanrath, Aidan T., additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Clair, additional, Harrison, Thomas D., additional, Harrison, Daisy, additional, Harris-Wright, Tara A., additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Haughney, John, additional, Hawkins, Sophia, additional, Hayano, Laís Y.M., additional, Head, Ian, additional, Heath, Paul T., additional, Henry, John Aaron, additional, Hermosin Herrera, Macarena, additional, Hettle, David B., additional, Higa, Cristhiane, additional, Hill, Jennifer, additional, Hodges, Gina, additional, Hodgson, Susanne, additional, Horne, Elizea, additional, Hou, Mimi M., additional, Houlihan, Catherine F., additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Hurley, Katrina, additional, Huson, Claire, additional, Hyams, Catherine, additional, Hyder-Wright, Angela, additional, Ikram, Sabina, additional, Ishwarbhai, Alka, additional, Iveson, Poppy, additional, Iyer, Vidyashankara, additional, Jackson, Frederic, additional, Jackson, Susan, additional, Jaumdally, Shameem, additional, Jeffers, Helen, additional, Jesudason, Natasha, additional, Jones, Carina, additional, Jones, Christopher, additional, Jones, Kathryn, additional, Jones, Elizabeth, additional, Jorge, Marianna Rocha, additional, Joshi, Amar, additional, Júnior, Eduardo A.M.S., additional, Kailath, Reshma, additional, Kana, Faeeza, additional, Kar, Arnab, additional, Karampatsas, Konstantinos, additional, Kasanyinga, Mwila, additional, Kay, Linda, additional, Keen, Jade, additional, Kellett Wright, Johanna, additional, Kelly, Elizabeth J., additional, Kelly, Debbie, additional, Kelly, Dearbhla M., additional, Kelly, Sarah, additional, Kerr, David, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Khurana, Ankush, additional, Kidd, Sarah, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, Kinch, Patrick, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Kluczna, Diana M., additional, Knapper, Francesca, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lages, Pedro M., additional, Lang, Matilda, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lawrie, Alison M., additional, Lazarus, Erica M., additional, Leach, Amanda, additional, Lees, Emily A., additional, Lelliott, Alice, additional, Lemm, Nana-Marie, additional, Lessa, Alvaro Edson Ramos, additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Liatsikos, Konstantinos, additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Adam, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Lora, Leandro Bonecker, additional, Luz, Kleber Giovanni, additional, MacDonald, Jonathan C., additional, MacGregor, Gordon, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Makambwa, Edson, additional, Makinson, Rebecca, additional, Malahleha, Mookho, additional, Malamatsho, Ross, additional, Mallett, Garry, additional, Manning, Nicola, additional, Mansatta, Kushal, additional, Maoko, Takalani, additional, Marinou, Spyridoula, additional, Marlow, Emma, additional, Marques, Gabriela N., additional, Marriott, Paula, additional, Marshall, Richard P., additional, Marshall, Julia L., additional, Masenya, Masebole, additional, Masilela, Mduduzi, additional, Masters, Shauna K., additional, Mathew, Moncy, additional, Matlebjane, Hosea, additional, Matshidiso, Kedidimetse, additional, Mazur, Olga, additional, Mazzella, Andrea, additional, McCaughan, Hugh, additional, McEwan, Joanne, additional, McGlashan, Joanna, additional, McInroy, Lorna, additional, McRobert, Nicky, additional, McSwiggan, Steve, additional, Megson, Clare, additional, Mehdipour, Savviz, additional, Meijs, Wilma, additional, Mendonça, Renata N.Õ., additional, Mentzer, Alexander J., additional, Mesquita, Ana Carolina F., additional, Miralhes, Patricia, additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Mnyakeni, Sibusiso, additional, Moghaddas, Fiona, additional, Molapo, Kgaogelo, additional, Moloi, Mapule, additional, Moore, Maria, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan J., additional, Morris, Sheila, additional, Morrison, Hazel, additional, Morselli, Franca, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Mottay, Lynelle, additional, Moultrie, Andrew, additional, Moyo, Nathifa, additional, Mpelembue, Mushiya, additional, Msomi, Sibekezelo, additional, Mugodi, Yvonne, additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Alasdair, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Myerscough, Christopher, additional, Naik, Gurudutt, additional, Naker, Kush, additional, Nastouli, Eleni, additional, Ndlovu, Bongani, additional, Nikolaou, Elissavet, additional, Njenga, Cecilia, additional, Noal, Helena C., additional, Noé, Andrés, additional, Novaes, Gabrielle, additional, Nugent, Fay L., additional, Nunes, Géssika Lanzillo A., additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Oelofse, Suzette, additional, Oguti, Blanche, additional, Olchawski, Victoria, additional, Oldfield, Neil J., additional, Oliveira, Marianne G., additional, Oliveira, Catarina, additional, Oliveira, Isabelle Silva Queiroz, additional, Oommen-Jose, Aylin, additional, Oosthuizen, Angela, additional, O'Reilly, Paula, additional, O'Reilly, Peter J., additional, Osborne, Piper, additional, Owen, David R.J., additional, Owen, Lydia, additional, Owens, Daniel, additional, Owino, Nelly, additional, Pacurar, Mihaela, additional, Paiva, Brenda V.B., additional, Palhares, Edna M.F., additional, Palmer, Susan, additional, Parracho, Helena M. R.T., additional, Parsons, Karen, additional, Patel, Dipak, additional, Patel, Bhumika, additional, Patel, Faeezah, additional, Patrick-Smith, Maia, additional, Payne, Ruth O., additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Pennington, Anna, additional, Peralta Alvarez, Marco Polo, additional, Pereira Stuchi, Bruno Pereira, additional, Perez, Ana Luiza, additional, Perinpanathan, Tanaraj, additional, Perring, James, additional, Perumal, Rubeshan, additional, Petkar, Sahir Yusuf, additional, Philip, Tricia, additional, Phillips, Jennifer, additional, Phohu, Mary Kgomotso, additional, Pickup, Lorinda, additional, Pieterse, Sonja, additional, Pinheiro, Jessica Morgana, additional, Piper, Jo, additional, Pipini, Dimitra, additional, Plank, Mary, additional, Plant, Sinéad, additional, Pollard, Samuel, additional, Pooley, Jennifer, additional, Pooran, Anil, additional, Poulton, Ian, additional, Powers, Claire, additional, Presa, Fernando B., additional, Price, David A., additional, Price, Vivien, additional, Primeira, Marcelo R., additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Quaid, Sheena, additional, Rabara, Ria, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Rajeswaran, Thurkka, additional, Ramos, Leonardo, additional, Ramos, Alberto San Francisco, additional, Ramos Lopez, Fernando, additional, Rampling, Tommy, additional, Rand, Jade, additional, Ratcliffe, Helen, additional, Rawlinson, Tom, additional, Rea, David, additional, Rees, Byron, additional, Resuello-Dauti, Mila, additional, Reyes Pabon, Emilia, additional, Rhead, Sarah, additional, Riaz, Tawassal, additional, Ricamara, Marivic, additional, Richards, Alexander, additional, Richter, Alex, additional, Ritchie, Neil, additional, Ritchie, Adam J., additional, Robbins, Alexander J., additional, Roberts, Hannah, additional, Robinson, Ryan E., additional, Roche, Sophie, additional, Rollier, Christine, additional, Rose, Louisa, additional, Ross Russell, Amy L., additional, Rossouw, Lindie, additional, Royal, Simon, additional, Rudiansyah, Indra, additional, Ryalls, Kim, additional, Sabine, Charlotte, additional, Saich, Stephen, additional, Sale, Jessica C., additional, Salman, Ahmed M., additional, Salvador, Natalia, additional, Salvador, Stephannie, additional, Sampaio, Milla Dias, additional, Samson, Annette D., additional, Sanchez-Gonzalez, Amada, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Santos, Erika, additional, Santos Guerra, Mayara F.S., additional, Satti, Iman, additional, Saunders, Jack E., additional, Saunders, Caroline, additional, Sayed, Aakifah Bibi Arif, additional, Schim van der Loeff, Ina, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin R., additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Senger, Roberta, additional, Serrano, Sonia, additional, Shaik, Imam, additional, Sharpe, Hannah R., additional, Sharrocks, Katherine, additional, Shaw, Robert, additional, Shea, Adam, additional, Sheehan, Emma, additional, Shepherd, Amy, additional, Shiham, Farah, additional, Silk, Sarah E., additional, Silva-Reyes, Laura, additional, Silveira, Lidiana B. T.D., additional, Silveira, Mariana B.V., additional, Singh, Nisha, additional, Sinha, Jaisi, additional, Skelly, Donal T., additional, Smith, Daniel C., additional, Smith, Nick, additional, Smith, Holly E., additional, Smith, David J., additional, Smith, Catherine C., additional, Soares, Airanuédida S., additional, Solórzano, Carla, additional, Sorio, Guilherme L., additional, Sorley, Kim, additional, Sosa-Rodriguez, Tiffany, additional, Souza, Cinthia M.C.D.L., additional, Souza, Bruno S.D.F., additional, Souza, Alessandra R., additional, Souza Lopez, Thamyres, additional, Sowole, Luciana, additional, Spencer, Alexandra J., additional, Spoors, Louise, additional, Stafford, Lizzie, additional, Stamford, Imogen, additional, Stein, Ricardo, additional, Stockdale, Lisa, additional, Stockwell, Lisa V., additional, Strickland, Louise H., additional, Stuart, Arabella, additional, Sturdy, Ann, additional, Sutton, Natalina, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taoushanis, Carol, additional, Tarr, Alexander W., additional, Tarrant, Richard, additional, Taylor, Keja, additional, Taylor, Ursula, additional, Taylor, Iona Jennifer, additional, Taylor, Justin, additional, te Water Naude, Rebecca, additional, Templeton, Kate, additional, Themistocleous, Yrene, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Kelly, additional, Thomas, Tonia M., additional, Thombrayil, Asha, additional, Thompson, Julia, additional, Thompson, Fawziyah, additional, Thompson, Ameeka, additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thornton-Jones, Viv, additional, Thotusi, Larissa H.S., additional, Tighe, Patrick J., additional, Tinoco, Lygia Accioly, additional, Tiongson, Gerlynn Ferreras, additional, Tladinyane, Bonolo, additional, Tomasicchio, Michele, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julia A., additional, Trillana, Gerry, additional, Trinham, Charlotte, additional, Trivett, Rose, additional, Truby, Adam, additional, Tsheko, Betty Lebogang, additional, Tubb, Philippa, additional, Turabi, Aadil, additional, Turner, Richard, additional, Turner, Cheryl, additional, Turner, Nicola, additional, Tyagi, Bhavya, additional, Ulaszewska, Marta, additional, Underwood, Benjamin R., additional, van Eck, Samual, additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije K., additional, Vichos, Iason, additional, Vieira, Taiane A., additional, Walker, Gemma, additional, Walker, Laura, additional, Wand, Matthew E., additional, Wardell, Theresa, additional, Warimwe, George M., additional, Warren, Sarah C., additional, Watkins, Bridget, additional, Watson, Marion E.E., additional, Watson, Ekaterina, additional, Webb, Stewart, additional, Webster, Angela, additional, Welch, Jessica, additional, Wellbelove, Zoe, additional, Wells, Jeanette H., additional, West, Alison J., additional, White, Beth, additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Williams, Rachel L., additional, Willingham, Silvia, additional, Winslow, Rebecca, additional, Woods, Danielle, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Danny, additional, Wroblewska, Marzena, additional, Yao, Andy, additional, Yim, Yee Ting Nicole, additional, Zambrano, Marina Bauer, additional, Zimmer, Rafael Leal, additional, Zizi, Dalila, additional, and Zuidewind, Peter, additional
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- 2021
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19. Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
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Cook, Jonathan A, primary, Baldwin, Mathew, additional, Cooper, Cushla, additional, Nagra, Navraj S, additional, Crocker, Joanna C, additional, Glaze, Molly, additional, Greenall, Gemma, additional, Rangan, Amar, additional, Kottam, Lucksy, additional, Rees, Jonathan L, additional, Farrar-Hockley, Dair, additional, Merritt, Naomi, additional, Hopewell, Sally, additional, Beard, David, additional, Thomas, Michael, additional, Dritsaki, Melina, additional, and Carr, Andrew J, additional
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- 2021
- Full Text
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20. Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial
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Rangan, Amar, Brealey, Stephen, Keding, Ada, Corbacho, Belen, Northgraves, Matthew, Kottam, Lucksy, Goodchild, Lorna, Srikesavan, Cynthia, Rex, Saleema, Charalambous, Charalambos, Hanchard, Nigel, Armstrong, Alison, Brooksbank, Andrew, Carr, Andrew, Cooper, Cushla, Dias, Joseph, Donnelly, Iona, Hewitt, Catherine, Lamb, Sarah, McDaid, Catriona, Richardson, Gerry, Rodgers, Sara, Sharp, Emma, SPENCER, SALLY, Torgerson, David, Toye, Francine, Rangan, Amar, Brealey, Stephen, Keding, Ada, Corbacho, Belen, Northgraves, Matthew, Kottam, Lucksy, Goodchild, Lorna, Srikesavan, Cynthia, Rex, Saleema, Charalambous, Charalambos, Hanchard, Nigel, Armstrong, Alison, Brooksbank, Andrew, Carr, Andrew, Cooper, Cushla, Dias, Joseph, Donnelly, Iona, Hewitt, Catherine, Lamb, Sarah, McDaid, Catriona, Richardson, Gerry, Rodgers, Sara, Sharp, Emma, SPENCER, SALLY, Torgerson, David, and Toye, Francine
- Abstract
Summary Background Manipulation under anaesthesia and arthroscopic capsular release are costly and invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We compared these two surgical interventions with early structured physiotherapy plus steroid injection. Methods In this multicentre, pragmatic, three-arm, superiority randomised trial, patients referred to secondary care for treatment of primary frozen shoulder were recruited from 35 hospital sites in the UK. Participants were adults (≥18 years) with unilateral frozen shoulder, characterised by restriction of passive external rotation (≥50%) in the affected shoulder. Participants were randomly assigned (2:2:1) to receive manipulation under anaesthesia, arthroscopic capsular release, or early structured physiotherapy. In manipulation under anaesthesia, the surgeon manipulated the affected shoulder to stretch and tear the tight capsule while the participant was under general anaesthesia, supplemented by a steroid injection. Arthroscopic capsular release, also done under general anaesthesia, involved surgically dividing the contracted anterior capsule in the rotator interval, followed by manipulation, with optional steroid injection. Both forms of surgery were followed by postprocedural physiotherapy. Early structured physiotherapy involved mobilisation techniques and a graduated home exercise programme supplemented by a steroid injection. Both early structured physiotherapy and postprocedural physiotherapy involved 12 sessions during up to 12 weeks. The primary outcome was the Oxford Shoulder Score (OSS; 0–48) at 12 months after randomisation, analysed by initial randomisation group. We sought a target difference of 5 OSS points between physiotherapy and either form of surgery, or 4 points between manipulation and capsular release. The trial registration is ISRCTN48804508. Findings Between April 1, 2015, and Dec 31, 2017, we screened 914 patients, of whom 503 (55%) were r
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- 2020
21. Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT
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Brealey, Stephen, Northgraves, Matthew, Kottam, Lucksy, Keding, Ada, Corbacho, Belen, Goodchild, Lorna, Srikesavan, Cynthia, Rex, Saleema, Charalambous, Charalambos P., Hanchard, Nigel, Armstrong, Alison, Brooksbank, Andrew, Carr, Andrew, Cooper, Cushla, Dias, Joseph, Donnelly, Iona, Hewitt, Catherine, Lamb, Sarah E, McDaid, Catriona, Richardson, Gerry, Rodgers, Sara, Sharp, Emma, Spencer, Sally, Torgerson, David, Toye, Francine, Rangan, Amar, Brealey, Stephen, Northgraves, Matthew, Kottam, Lucksy, Keding, Ada, Corbacho, Belen, Goodchild, Lorna, Srikesavan, Cynthia, Rex, Saleema, Charalambous, Charalambos P., Hanchard, Nigel, Armstrong, Alison, Brooksbank, Andrew, Carr, Andrew, Cooper, Cushla, Dias, Joseph, Donnelly, Iona, Hewitt, Catherine, Lamb, Sarah E, McDaid, Catriona, Richardson, Gerry, Rodgers, Sara, Sharp, Emma, Spencer, Sally, Torgerson, David, Toye, Francine, and Rangan, Amar
- Abstract
Background Frozen shoulder causes pain and stiffness. It affects around 10% of people in their fifties and is slightly more common in women. Costly and invasive surgical interventions are used, without high-quality evidence that these are effective. Objectives To compare the clinical effectiveness and cost-effectiveness of three treatments in secondary care for adults with frozen shoulder; to qualitatively explore the acceptability of these treatments to patients and health-care professionals; and to update a systematic review to explore the trial findings in the context of existing evidence for the three treatments. Design This was a pragmatic, parallel-group, multicentre, open-label, three-arm, randomised superiority trial with unequal allocation (2 : 2 : 1). An economic evaluation and a nested qualitative study were also carried out. Setting The orthopaedic departments of 35 hospitals across the UK were recruited from April 2015, with final follow-up in December 2018. Participants Participants were adults (aged ≥ 18 years) with unilateral frozen shoulder, characterised by restriction of passive external rotation in the affected shoulder to < 50% of the opposite shoulder, and with plain radiographs excluding other pathology. Interventions The inventions were early structured physiotherapy with a steroid injection, manipulation under anaesthesia with a steroid injection and arthroscopic capsular release followed by manipulation. Both of the surgical interventions were followed with post-procedural physiotherapy. Main outcome measures The primary outcome and end point was the Oxford Shoulder Score at 12 months post randomisation. A difference of 5 points between early structured physiotherapy and manipulation under anaesthesia or arthroscopic capsular release or of 4 points between manipulation under anaesthesia and arthroscopic capsular release was judged clinically important. Results The mean age of the 503 participants was 54 years; 319 were female (63%) and 1
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- 2020
22. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
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Voysey, Merryn, primary, Clemens, Sue Ann Costa, additional, Madhi, Shabir A, additional, Weckx, Lily Y, additional, Folegatti, Pedro M, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Baillie, Vicky L, additional, Barnabas, Shaun L, additional, Bhorat, Qasim E, additional, Bibi, Sagida, additional, Briner, Carmen, additional, Cicconi, Paola, additional, Collins, Andrea M, additional, Colin-Jones, Rachel, additional, Cutland, Clare L, additional, Darton, Thomas C, additional, Dheda, Keertan, additional, Duncan, Christopher J A, additional, Emary, Katherine R W, additional, Ewer, Katie J, additional, Fairlie, Lee, additional, Faust, Saul N, additional, Feng, Shuo, additional, Ferreira, Daniela M, additional, Finn, Adam, additional, Goodman, Anna L, additional, Green, Catherine M, additional, Green, Christopher A, additional, Heath, Paul T, additional, Hill, Catherine, additional, Hill, Helen, additional, Hirsch, Ian, additional, Hodgson, Susanne H C, additional, Izu, Alane, additional, Jackson, Susan, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kerridge, Simon, additional, Koen, Anthonet, additional, Kwatra, Gaurav, additional, Lazarus, Rajeka, additional, Lawrie, Alison M, additional, Lelliott, Alice, additional, Libri, Vincenzo, additional, Lillie, Patrick J, additional, Mallory, Raburn, additional, Mendes, Ana V A, additional, Milan, Eveline P, additional, Minassian, Angela M, additional, McGregor, Alastair, additional, Morrison, Hazel, additional, Mujadidi, Yama F, additional, Nana, Anusha, additional, O’Reilly, Peter J, additional, Padayachee, Sherman D, additional, Pittella, Ana, additional, Plested, Emma, additional, Pollock, Katrina M, additional, Ramasamy, Maheshi N, additional, Rhead, Sarah, additional, Schwarzbold, Alexandre V, additional, Singh, Nisha, additional, Smith, Andrew, additional, Song, Rinn, additional, Snape, Matthew D, additional, Sprinz, Eduardo, additional, Sutherland, Rebecca K, additional, Tarrant, Richard, additional, Thomson, Emma C, additional, Török, M Estée, additional, Toshner, Mark, additional, Turner, David P J, additional, Vekemans, Johan, additional, Villafana, Tonya L, additional, Watson, Marion E E, additional, Williams, Christopher J, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Pollard, Andrew J, additional, Aban, Marites, additional, Abayomi, Fatola, additional, Abeyskera, Kushala, additional, Aboagye, Jeremy, additional, Adam, Matthew, additional, Adams, Kirsty, additional, Adamson, James, additional, Adelaja, Yemi A., additional, Adewetan, Gbadebo, additional, Adlou, Syed, additional, Ahmed, Khatija, additional, Akhalwaya, Yasmeen, additional, Akhalwaya, Saajida, additional, Alcock, Andrew, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Almeida, Thamires C. D. S. C, additional, Alves, Mariana P.S., additional, Amorim, Fabio, additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Appleby, Matthew, additional, Arbe-Barnes, Edward H., additional, Ariaans, Mark P., additional, Arns, Beatriz, additional, Arruda, Laiana, additional, Azi, Paula, additional, Azi, Lorena, additional, Babbage, Gavin, additional, Bailey, Catherine, additional, Baker, Kenneth F., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baldwin, Lisa, additional, Baleanu, Ioana, additional, Bandeira, Danieli, additional, Bara, Anna, additional, Barbosa, Marcella A.S., additional, Barker, Debbie, additional, Barlow, Gavin D., additional, Barnes, Eleanor, additional, Barr, Andrew S., additional, Barrett, Jordan R., additional, Barrett, Jessica, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beales, Emily, additional, Beckley, Rebecca, additional, Belij-Rammerstorfer, Sandra, additional, Bell, Jonathan, additional, Bellamy, Duncan, additional, Bellei, Nancy, additional, Belton, Sue, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Berry, Lisa, additional, Berzenyi, Daniella, additional, Beveridge, Amy, additional, Bewley, Kevin R., additional, Bexhell, Helen, additional, Bhikha, Sutika, additional, Bhorat, Asad E., additional, Bhorat, Zaheda E., additional, Bijker, Else, additional, Birch, Geeta, additional, Birch, Sarah, additional, Bird, Adam, additional, Bird, Olivia, additional, Bisnauthsing, Karen, additional, Bittaye, Mustapha, additional, Blackstone, Katherine, additional, Blackwell, Luke, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bodalia, Pritesh, additional, Boettger, Bruno C., additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Bradley, Penny, additional, Brenner, Tanja, additional, Brown, Phillip, additional, Brown, Claire, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Buchan, Ruaridh, additional, Budd, William, additional, Bulbulia, Yusuf A., additional, Bull, Melanie, additional, Burbage, Jamie, additional, Burhan, Hassan, additional, Burn, Aileen, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabera Puig, Ingrid, additional, Calderon, Gloria, additional, Calvert, Anna, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Cardoso, João R., additional, Carr, Melanie, additional, Carroll, Miles W., additional, Carson-Stevens, Andrew, additional, Carvalho, Yasmin de M., additional, Carvalho, José A.M., additional, Casey, Helen R., additional, Cashen, Paul, additional, Castro, Thais, additional, Castro, Lucia Carratala, additional, Cathie, Katrina, additional, Cavey, Ana, additional, Cerbino-Neto, José, additional, Chadwick, Jim, additional, Chapman, David, additional, Charlton, Sue, additional, Chelysheva, Irina, additional, Chester, Oliver, additional, Chita, Sunder, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Clark, Matthew, additional, Clarke, Andrea, additional, Clutterbuck, Elizabeth A., additional, Collins, Sarah L.K., additional, Conlon, Christopher P., additional, Connarty, Sean, additional, Coombes, Naomi, additional, Cooper, Cushla, additional, Cooper, Rachel, additional, Cornelissen, Lynne, additional, Corrah, Tumena, additional, Cosgrove, Catherine, additional, Cox, Tony, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Lorraine, additional, Cullen, Dan, additional, Cunha, Debora R.M.F., additional, Cunningham, Christina, additional, Cuthbertson, Fiona C., additional, Da Guarda, Suzete N. Farias, additional, da Silva, Larissa P., additional, Damratoski, Brad E., additional, Danos, Zsofia, additional, Dantas, Maria T.D.C., additional, Darroch, Paula, additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davids, Malika, additional, Davies, Sarah L., additional, Davies, Hannah, additional, Davis, Elizabeth, additional, Davis, Judith, additional, Davis, John, additional, De Nobrega, Maristela M.D., additional, De Oliveira Kalid, Lis Moreno, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Desai, Amisha, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, Dinelli, Maria I.S., additional, Dinesh, Tanya, additional, Docksey, Claire, additional, Dold, Christina, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Dos Santos, Tannyth, additional, dos Santos, Thainá G., additional, Dos Santos, Erika Pachecho, additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Driver, Kimberley, additional, Drury, Ruth, additional, Dunachie, Susanna J., additional, Durham, Benjamin S., additional, Dutra, Lidiana, additional, Easom, Nicholas J.W., additional, van Eck, Samual, additional, Edwards, Mandy, additional, Edwards, Nick J., additional, El Muhanna, Omar M., additional, Elias, Sean C., additional, Elmore, Mike, additional, English, Marcus, additional, Esmail, Alisgair, additional, Essack, Yakub Moosa, additional, Farmer, Eoghan, additional, Farooq, Mutjaba, additional, Farrar, Madi, additional, Farrugia, Leonard, additional, Faulkner, Beverley, additional, Fedosyuk, Sofiya, additional, Felle, Sally, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Flaxman, Amy, additional, Fletcher, James, additional, Fofie, Hazel, additional, Fok, Henry, additional, Ford, Karen J., additional, Fowler, Jamie, additional, Fraiman, Pedro H.A., additional, Francis, Emma, additional, Franco, Marilia M., additional, Frater, John, additional, Freire, Marilúcia S.M., additional, Fry, Samantha H., additional, Fudge, Sabrina, additional, Furze, Julie, additional, Fuskova, Michelle, additional, Galian-Rubio, Pablo, additional, Galiza, Eva, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Geddes, Ailsa, additional, Gibbons, Karyna A., additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Glynn, Sharon, additional, Godwin, Kerry, additional, Gokani, Karishma, additional, Goldoni, Ursula Carvalho, additional, Goncalves, Maria, additional, Gonzalez, Isabela G.S., additional, Goodwin, Jayne, additional, Goondiwala, Amina, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Grab, Janet, additional, Gracie, Lara, additional, Greenland, Melanie, additional, Greenwood, Nicola, additional, Greffrath, Johann, additional, Groenewald, Marisa M., additional, Grossi, Leonardo, additional, Gupta, Gaurav, additional, Hackett, Mark, additional, Hallis, Bassam, additional, Hamaluba, Mainga, additional, Hamilton, Elizabeth, additional, Hamlyn, Joseph, additional, Hammersley, Daniel, additional, Hanrath, Aidan T., additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Clair, additional, Harris, Tara, additional, Harrison, Thomas D., additional, Harrison, Daisy, additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Hassan, Shadin, additional, Haughney, John, additional, Hawkins, Sophia, additional, Hay, Jodie, additional, Head, Ian, additional, Henry, John, additional, Hermosin Herrera, Macarena, additional, Hettle, David B., additional, Hill, Jennifer, additional, Hodges, Gina, additional, Horne, Elizea, additional, Hou, Mimi M., additional, Houlihan, Catherine, additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Hurley, Katrina, additional, Huson, Claire, additional, Hyder-Wright, Angela, additional, Hyams, Catherine, additional, Ikram, Sabina, additional, Ishwarbhai, Alka, additional, Ivan, Monica, additional, Iveson, Poppy, additional, Iyer, Vidyashankara, additional, Jackson, Frederic, additional, De Jager, Jeanne, additional, Jaumdally, Shameem, additional, Jeffers, Helen, additional, Jesudason, Natasha, additional, Jones, Bryony, additional, Jones, Kathryn, additional, Jones, Elizabeth, additional, Jones, Christopher, additional, Jorge, Marianna Rocha, additional, Jose, Aylin, additional, Joshi, Amar, additional, Júnior, Eduardo A.M.S., additional, Kadziola, Joanne, additional, Kailath, Reshma, additional, Kana, Faeeza, additional, Karampatsas, Konstantinos, additional, Kasanyinga, Mwila, additional, Keen, Jade, additional, Kelly, Elizabeth J., additional, Kelly, Dearbhla M., additional, Kelly, Debbie, additional, Kelly, Sarah, additional, Kerr, David, additional, Kfouri, Renato de Ávila, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Kidd, Sarah, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, Kinch, Patrick, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Knapper, Francesca, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lang, Matilda, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lazarus, Erica M., additional, Leach, Amanda, additional, Lees, Emily A., additional, Lemm, Nana-Marie, additional, Lessa, Alvaro, additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Liatsikos, Kostas, additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Adam, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Lora, Leandro, additional, Lowthorpe, Vicki, additional, Luz, Kleber, additional, MacDonald, Jonathan C., additional, MacGregor, Gordon, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Makambwa, Edson, additional, Makinson, Rebecca, additional, Malahleha, Mookho, additional, Malamatsho, Ross, additional, Mallett, Garry, additional, Mansatta, Kushal, additional, Maoko, Takalani, additional, Mapetla, Katlego, additional, Marchevsky, Natalie G., additional, Marinou, Spyridoula, additional, Marlow, Emma, additional, Marques, Gabriela N., additional, Marriott, Paula, additional, Marshall, Richard P., additional, Marshall, Julia L., additional, Martins, Flávia J., additional, Masenya, Masebole, additional, Masilela, Mduduzi, additional, Masters, Shauna K., additional, Mathew, Moncy, additional, Matlebjane, Hosea, additional, Matshidiso, Kedidimetse, additional, Mazur, Olga, additional, Mazzella, Andrea, additional, McCaughan, Hugh, additional, McEwan, Joanne, additional, McGlashan, Joanna, additional, McInroy, Lorna, additional, McIntyre, Zoe, additional, McLenaghan, Daniela, additional, McRobert, Nicky, additional, McSwiggan, Steve, additional, Megson, Clare, additional, Mehdipour, Savviz, additional, Meijs, Wilma, additional, Mendonça, Renata N.Á., additional, Mentzer, Alexander J., additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Mnyakeni, Sibusiso, additional, Moghaddas, Fiona, additional, Molapo, Kgaogelo, additional, Moloi, Mapule, additional, Moore, Maria, additional, Moraes-Pinto, M. Isabel, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan, additional, Morris, Sheila, additional, Morris, Helen C., additional, Morselli, Franca, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Mottal, Lynelle, additional, Moultrie, Andrew, additional, Moya, Nathifa, additional, Mpelembue, Mushiya, additional, Msomi, Sibekezelo, additional, Mugodi, Yvonne, additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Alasdair, additional, Munro, Claire, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Myasaki, Celia Hatsuko, additional, Naik, Gurudutt, additional, Naker, Kush, additional, Nastouli, Eleni, additional, Nazir, Abida, additional, Ndlovu, Bongani, additional, Neffa, Fabio, additional, Njenga, Cecilia, additional, Noal, Helena, additional, Noé, Andrés, additional, Novaes, Gabrielle, additional, Nugent, Fay L., additional, Nunes, Géssika, additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Odam, Miranda, additional, Oelofse, Suzette, additional, Oguti, Blanche, additional, Olchawski, Victoria, additional, Oldfield, Neil J., additional, Oliveira, Marianne G., additional, Oliveira, Catarina, additional, Oosthuizen, Angela, additional, O'Reilly, Paula, additional, Osborne, Piper, additional, Owen, David R.J., additional, Owen, Lydia, additional, Owens, Daniel, additional, Owino, Nelly, additional, Pacurar, Mihaela, additional, Paiva, Brenda V.B., additional, Palhares, Edna M.F., additional, Palmer, Susan, additional, Parkinson, Sivapriyai, additional, Parracho, Helena M.R.T., additional, Parsons, Karen, additional, Patel, Dipak, additional, Patel, Bhumika, additional, Patel, Faeezah, additional, Patel, Kelly, additional, Patrick-Smith, Maia, additional, Payne, Ruth O., additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Pennington, Anna, additional, Peralta Alvarez, Marco Polo, additional, Perring, James, additional, Perry, Nicola, additional, Perumal, Rubeshan, additional, Petkar, Sahir, additional, Philip, Tricia, additional, Phillips, Daniel J., additional, Phillips, Jennifer, additional, Phohu, Mary Kgomotso, additional, Pickup, Lorinda, additional, Pieterse, Sonja, additional, Piper, Jo, additional, Pipini, Dimitra, additional, Plank, Mary, additional, Du Plessis, Joan, additional, Pollard, Samuel, additional, Pooley, Jennifer, additional, Pooran, Anil, additional, Poulton, Ian, additional, Powers, Claire, additional, Presa, Fernando B., additional, Price, David A., additional, Price, Vivien, additional, Primeira, Marcelo, additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Quaid, Sheena, additional, Rabara, Ria, additional, Radford, Alexandra, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Rajeswaran, Thurkka, additional, Ramos, Alberto San Francisco, additional, Ramos Lopez, Fernando, additional, Rampling, Tommy, additional, Rand, Jade, additional, Ratcliffe, Helen, additional, Rawlinson, Tom, additional, Rea, David, additional, Rees, Byron, additional, Reiné, Jesús, additional, Resuello-Dauti, Mila, additional, Reyes Pabon, Emilia, additional, Ribiero, Carla M., additional, Ricamara, Marivic, additional, Richter, Alex, additional, Ritchie, Neil, additional, Ritchie, Adam J., additional, Robbins, Alexander J., additional, Roberts, Hannah, additional, Robinson, Ryan E., additional, Robinson, Hannah, additional, Rocchetti, Talita T., additional, Rocha, Beatriz Pinho, additional, Roche, Sophie, additional, Rollier, Christine, additional, Rose, Louisa, additional, Ross Russell, Amy L., additional, Rossouw, Lindie, additional, Royal, Simon, additional, Rudiansyah, Indra, additional, Ruiz, Sarah, additional, Saich, Stephen, additional, Sala, Claudia, additional, Sale, Jessica, additional, Salman, Ahmed M., additional, Salvador, Natalia, additional, Salvador, Stephannie, additional, Sampaio, Milla, additional, Samson, Annette D., additional, Sanchez-Gonzalez, Amada, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Santos, Erika, additional, Santos Guerra, Mayara F.S., additional, Satti, Iman, additional, Saunders, Jack E., additional, Saunders, Caroline, additional, Sayed, Aakifah, additional, Schim van der Loeff, Ina, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin, additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Senger, Roberta, additional, Serrano, Sonia, additional, Shah, Rajiv, additional, Shaik, Imam, additional, Sharpe, Hannah E., additional, Sharrocks, Katherine, additional, Shaw, Robert, additional, Shea, Adam, additional, Shepherd, Amy, additional, Shepherd, James G., additional, Shiham, Farah, additional, Sidhom, Emad, additional, Silk, Sarah E., additional, da Silva Moraes, Antonio Carlos, additional, Silva-Junior, Gilberto, additional, Silva-Reyes, Laura, additional, Silveira, Anderson D., additional, Silveira, Mariana B.V., additional, Sinha, Jaisi, additional, Skelly, Donal T., additional, Smith, Daniel C., additional, Smith, Nick, additional, Smith, Holly E., additional, Smith, David J., additional, Smith, Catherine C., additional, Soares, Airanuédida, additional, Soares, Tiago, additional, Solórzano, Carla, additional, Sorio, Guilherme L., additional, Sorley, Kim, additional, Sosa-Rodriguez, Tiffany, additional, Souza, Cinthia M.C.D.L., additional, Souza, Bruno S.D.F., additional, Souza, Alessandra R., additional, Spencer, Alexandra J., additional, Spina, Fernanda, additional, Spoors, Louise, additional, Stafford, Lizzie, additional, Stamford, Imogen, additional, Starinskij, Igor, additional, Stein, Ricardo, additional, Steven, Jill, additional, Stockdale, Lisa, additional, Stockwell, Lisa V., additional, Strickland, Louise H., additional, Stuart, Arabella C., additional, Sturdy, Ann, additional, Sutton, Natalina, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taoushanis, Carol, additional, Tarr, Alexander W., additional, Taylor, Keja, additional, Taylor, Ursula, additional, Taylor, Iona Jennifer, additional, Taylor, Justin, additional, te Water Naude, Rebecca, additional, Themistocleous, Yrene, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Kelly, additional, Thomas, Tonia M., additional, Thombrayil, Asha, additional, Thompson, Fawziyah, additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thompson, Ameeka, additional, Thomson, Julia, additional, Thornton-Jones, Viv, additional, Tighe, Patrick J., additional, Tinoco, Lygia Accioly, additional, Tiongson, Gerlynn, additional, Tladinyane, Bonolo, additional, Tomasicchio, Michele, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julia, additional, Trillana, Gerry, additional, Trinham, Charlotte, additional, Trivett, Rose, additional, Truby, Adam, additional, Tsheko, Betty Lebogang, additional, Turabi, Aadil, additional, Turner, Richard, additional, Turner, Cheryl, additional, Ulaszewska, Marta, additional, Underwood, Benjamin R., additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije, additional, Vichos, Iason, additional, Vieira, Taiane, additional, Waddington, Claire S., additional, Walker, Laura, additional, Wallis, Erica, additional, Wand, Matthew, additional, Warbick, Deborah, additional, Wardell, Theresa, additional, Warimwe, George, additional, Warren, Sarah C., additional, Watkins, Bridget, additional, Watson, Ekaterina, additional, Webb, Stewart, additional, Webb-Bridges, Alice, additional, Webster, Angela, additional, Welch, Jessica, additional, Wells, Jeanette, additional, West, Alison, additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Williams, Rachel L., additional, Winslow, Rebecca, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Danny, additional, Wroblewska, Marzena, additional, Yao, Andy, additional, Zimmer, Rafael, additional, Zizi, Dalila, additional, and Zuidewind, Peter, additional
- Published
- 2021
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23. Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
- Author
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Ramasamy, Maheshi N, primary, Minassian, Angela M, additional, Ewer, Katie J, additional, Flaxman, Amy L, additional, Folegatti, Pedro M, additional, Owens, Daniel R, additional, Voysey, Merryn, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Babbage, Gavin, additional, Belij-Rammerstorfer, Sandra, additional, Berry, Lisa, additional, Bibi, Sagida, additional, Bittaye, Mustapha, additional, Cathie, Katrina, additional, Chappell, Harry, additional, Charlton, Sue, additional, Cicconi, Paola, additional, Clutterbuck, Elizabeth A, additional, Colin-Jones, Rachel, additional, Dold, Christina, additional, Emary, Katherine R W, additional, Fedosyuk, Sofiya, additional, Fuskova, Michelle, additional, Gbesemete, Diane, additional, Green, Catherine, additional, Hallis, Bassam, additional, Hou, Mimi M, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kelly, Elizabeth J, additional, Kerridge, Simon, additional, Lawrie, Alison M, additional, Lelliott, Alice, additional, Lwin, May N, additional, Makinson, Rebecca, additional, Marchevsky, Natalie G, additional, Mujadidi, Yama, additional, Munro, Alasdair P S, additional, Pacurar, Mihaela, additional, Plested, Emma, additional, Rand, Jade, additional, Rawlinson, Thomas, additional, Rhead, Sarah, additional, Robinson, Hannah, additional, Ritchie, Adam J, additional, Ross-Russell, Amy L, additional, Saich, Stephen, additional, Singh, Nisha, additional, Smith, Catherine C, additional, Snape, Matthew D, additional, Song, Rinn, additional, Tarrant, Richard, additional, Themistocleous, Yrene, additional, Thomas, Kelly M, additional, Villafana, Tonya L, additional, Warren, Sarah C, additional, Watson, Marion E E, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Faust, Saul N, additional, Pollard, Andrew J, additional, Aboagye, Jeremy, additional, Adams, Kelly, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Allison, Jennifer L., additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Arbe-Barnes, Edward H., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baleanu, Ioana, additional, Barker, Debbie, additional, Barnes, Eleanor, additional, Barrett, Jordan R., additional, Barrett, Kelly, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beckley, Rebecca, additional, Bellamy, Duncan, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Beveridge, Amy, additional, Bewley, Kevin, additional, Bijker, Else M., additional, Birch, Geeta, additional, Blackwell, Luke, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Boukas, Konstantinos, additional, Bower, Thomas, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Brenner, Tanja, additional, Brown, Phillip, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Burbage, Jamie, additional, Burgoyne, Joshua, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabera Puig, Ingrid, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Carr, Melanie, additional, Carroll, Miles W., additional, Cashen, Paul, additional, Cavey, Ana, additional, Chadwick, Jim, additional, Challis, Ruth, additional, Chapman, David, additional, Charles, David, additional, Chelysheva, Irina, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Collins, Sarah, additional, Conlon, Christopher P., additional, Coombes, Naomi S., additional, Cooper, Rachel, additional, Cooper, Cushla, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Dan, additional, Cunningham, Christina, additional, Cuthbertson, Fiona, additional, Datoo, Brad E., additional, Dando, Lynne, additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davies, Hannah, additional, Davies, Sarah, additional, Davis, Elizabeth J., additional, Davis, Judith, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, DiTirro, Danielle, additional, Docksey, Claire, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Drury, Ruth E., additional, Dunachie, Susanna J., additional, Edwards, Christopher J., additional, Edwards, Nick J., additional, El Muhanna, Omar, additional, Elias, Sean C., additional, Elliott, Ryan S., additional, Elmore, Michael J., additional, English, Marcus Rex, additional, Felle, Sally, additional, Feng, Shuo, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Fixmer, Carine, additional, Ford, Karen J., additional, Fowler, Jamie, additional, Francis, Emma, additional, Frater, John, additional, Furze, Julie, additional, Galian-Rubio, Pablo, additional, Galloway, Celine, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Gibbons, Felicity, additional, Gibbons, Karyna, additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Godwin, Kerry, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Goulston, Lyndsey, additional, Grabau, Caroline, additional, Gracie, Lara, additional, Graham, Nichola, additional, Greenwood, Nicola, additional, Griffiths, Oliver, additional, Gupta, Gaurav, additional, Hamilton, Elizabeth, additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Tara, additional, Harrison, Daisy, additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Haskell, Louise, additional, Hawkins, Sophia, additional, Henry, John Aaron, additional, Hermosin Herrera, Macarena, additional, Hill, David, additional, Hill, Jennifer, additional, Hodges, Gina, additional, Hodgson, Susanne H.C., additional, Horton, Katie L., additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Howes, Jessica, additional, Huang, Ben, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Iveson, Poppy, additional, Jackson, Frederic, additional, Jackson, Susan, additional, Jauregui, Sam, additional, Jeffers, Helen, additional, Jones, Bryony, additional, Jones, Christine E., additional, Jones, Elizabeth, additional, Jones, Kathryn, additional, Joshi, Amar, additional, Kailath, Reshma, additional, Keen, Jade, additional, Kelly, Dearbhla M., additional, Kelly, Sarah, additional, Kelly, Debbie, additional, Kerr, David, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lee, Arlene, additional, Lee, Kim Y.N., additional, Lees, Emily A., additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Mallett, Garry, additional, Mansatta, Kushal, additional, Marinou, Spyridoula, additional, Marius, Phedra, additional, Marlow, Emma, additional, Marriott, Paula, additional, Marshall, Julia L., additional, Martin, Jane, additional, Masters, Shauna, additional, McEwan, Joanne, additional, McGlashan, Joanna L., additional, McInroy, Lorna, additional, McRobert, Nicky, additional, Megson, Clare, additional, Mentzer, Alexander J., additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Moore, Maria, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan J., additional, Morrison, Hazel Morrison, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Moya, Nathifa A., additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Claire, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Noé, Andrés, additional, Nugent, Fay L., additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Oguti, Blanché, additional, Olchawski, Victoria, additional, Oliveira, Catarina, additional, O'Reilly, Peter John, additional, Osborne, Piper, additional, Owen, Lydia, additional, Owino, Nelly, additional, Papageorgiou, Panagiotis, additional, Parracho, Helena, additional, Parsons, Karen, additional, Patel, Bhumika, additional, Patrick-Smith, Maia, additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Peralta-Alvarez, Marco Polo, additional, Perring, James, additional, Petropoulos, Christos, additional, Phillips, Daniel J., additional, Pipini, Dimitra, additional, Pollard, Samuel, additional, Poulton, Ian, additional, Pratt, Danny, additional, Presland, Laura, additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Rabara, Ria, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Ramos Lopez, Fernando, additional, Ratcliffe, Helen, additional, Rayhan, Sara, additional, Rees, Byron, additional, Reyes Pabon, Emilia, additional, Roberts, Hannah, additional, Robertson, Isla, additional, Roche, Sophie, additional, Rollier, Christine S., additional, Romani, Rossana, additional, Rose, Zoe, additional, Rudiansyah, Indra, additional, Sabheha, Sabeha, additional, Salvador, Stephannie, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Satti, Iman, additional, Sayce, Chloe, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin, additional, Sedik, Cynthia, additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Selby, Beatrice, additional, Shaik, Imam, additional, Sharpe, Hannah R., additional, Shaw, Robert, additional, Shea, Adam, additional, Silk, Sarah, additional, Silva-Reyes, Laura, additional, Skelly, Donal T., additional, Smith, David J., additional, Smith, Daniel C., additional, Smith, Nicholas, additional, Spencer, Alexandra J., additional, Spoors, Louise, additional, Stafford, Elizabeth, additional, Stamford, Imogen, additional, Stockdale, Lisa, additional, Stockley, David, additional, Stockwell, Lisa V., additional, Stokes, Matthew, additional, Strickland, Louise H., additional, Stuart, Arabella, additional, Sulaiman, Sulaiman, additional, Summerton, Eloise, additional, Swash, Zoe, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taylor, Iona, additional, Taylor, Keja, additional, Taylor, Ursula, additional, te Water Naude, Rebecca, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Tonia M., additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thornton-Jones, Viv, additional, Tinh, Lan, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julian A., additional, Truby, Adam, additional, Turner, Cheryl, additional, Turner, Richard, additional, Ulaszewska, Marta, additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije K., additional, Vichos, Iason, additional, Walker, Laura, additional, Wand, Matthew E., additional, Watkins, Bridget, additional, Welch, Jessica, additional, West, Alison J., additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Daniel, additional, Wrin, Terri, additional, Yao, Xin Li, additional, Zbarcea, Diana-Andreea, additional, and Zizi, Dalila, additional
- Published
- 2020
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24. Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT
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Brealey, Stephen, primary, Northgraves, Matthew, additional, Kottam, Lucksy, additional, Keding, Ada, additional, Corbacho, Belen, additional, Goodchild, Lorna, additional, Srikesavan, Cynthia, additional, Rex, Saleema, additional, Charalambous, Charalambos P, additional, Hanchard, Nigel, additional, Armstrong, Alison, additional, Brooksbank, Andrew, additional, Carr, Andrew, additional, Cooper, Cushla, additional, Dias, Joseph, additional, Donnelly, Iona, additional, Hewitt, Catherine, additional, Lamb, Sarah E, additional, McDaid, Catriona, additional, Richardson, Gerry, additional, Rodgers, Sara, additional, Sharp, Emma, additional, Spencer, Sally, additional, Torgerson, David, additional, Toye, Francine, additional, and Rangan, Amar, additional
- Published
- 2020
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25. Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial
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Rangan, Amar, primary, Brealey, Stephen D, additional, Keding, Ada, additional, Corbacho, Belen, additional, Northgraves, Matthew, additional, Kottam, Lucksy, additional, Goodchild, Lorna, additional, Srikesavan, Cynthia, additional, Rex, Saleema, additional, Charalambous, Charalambos P, additional, Hanchard, Nigel, additional, Armstrong, Alison, additional, Brooksbank, Andrew, additional, Carr, Andrew, additional, Cooper, Cushla, additional, Dias, Joseph J, additional, Donnelly, Iona, additional, Hewitt, Catherine, additional, Lamb, Sarah E, additional, McDaid, Catriona, additional, Richardson, Gerry, additional, Rodgers, Sara, additional, Sharp, Emma, additional, Spencer, Sally, additional, Torgerson, David, additional, Toye, Francine, additional, Ahrens, Philip, additional, Baldwick, Cheryl, additional, Bidwai, Amit, additional, Butt, Asim, additional, Candal-Couto, Jamie, additional, Charalambous, Charalambos, additional, Crowther, Mark, additional, Drew, Steve, additional, Garg, Sunil, additional, Hawken, Richard, additional, Kelly, Cormac, additional, Kent, Matthew, additional, Kumar, Kapil, additional, Lawrence, Tom, additional, Little, Christopher, additional, Macleod, Iain, additional, Malal, Jodi George, additional, Matthews, Tim, additional, McClelland, Damian, additional, Millar, Neal, additional, Motkur, Prabhakar, additional, Nanda, Rajesh, additional, Peach, Chris Peach, additional, Peckham, Tim, additional, Rai, Jayanti, additional, Ray, Ravi, additional, Robinson, Douglas, additional, Rosell, Philip, additional, Ruman, Adam, additional, Saithna, Adnan, additional, Senior, Colin, additional, Shanker, Harish, additional, Sheridan, Barnaby, additional, Theivendran, Kanthan, additional, Thomas, Simon, additional, and Venateswaran, Balachandran, additional
- Published
- 2020
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26. Injection versus decompression for carpal tunnel syndrome (INDICATE): feasibility trial
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Berwin, James T., primary, Cooper, Cushla, additional, and Mason, Will, additional
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- 2020
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27. NINJA trial: should the nail plate be replaced or discarded after nail bed repair in children? Protocol for a multicentre randomised control trial
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Jain, Abhilash, primary, Jones, Amy, additional, Gardiner, Matthew D, additional, Cooper, Cushla, additional, Sierakowski, Adam, additional, Dritsaki, Melina, additional, Png, May Ee, additional, Stokes, Jamie R, additional, Shirkey, Beverly, additional, Cook, Jonathan, additional, Beard, David, additional, and Greig, Aina V H, additional
- Published
- 2019
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28. The UKUFF trial and the NIHR comprehensive local research networks
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Carr, Andrew and Cooper, Cushla
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- 2009
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29. The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
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L, Rooshenas, LJ, Scott, JM, Blazeby, CA, Rogers, KM, Tilling, S, Husbands, C, Conefrey, N, Mills, RC, Stein, C, Metcalfe, AJ, Carr, DJ, Beard, T., Davis, S, Paramasivan, M, Jepson, K, Avery, D, Elliott, C, Wilson, JL, Donovan, Rogers, Chris A., Andrews, Robert, Blazeby, Jane M., Byrne, James, Donovan, Jenny L., Kelly, Jamie, Mazza, Graziella, Mahon, David, Noble, Hamish, Reeves, Barnaby C., Thompson, Janice L., Wordsworth, Sarah, Welbourn, Richard, Beard, David, Carr, Andrew, Cook, Jonathan, Cooper, Cushla, Dean, Benjamin, Gray, Alastair, Gwilym, Stephen, Judge, Andrew, Merritt, Naomi, Moser, Jane, Rees, Jonathan, Rombach, Ines, Savulescu, Julian, Tracey, Irene, Wartolowska, Karolina, Tan, Wei, Mills, Nicola, Karantana, Alexia, Sprange, Kirsty, Duley, Lelia, Elliott, Daisy, Hollingworth, William, Montgomery, Alan A., Davis, Tim, Stein, Rob, Bartlett, John, Cameron, David, Campbell, Amy, Canney, Peter, Dunn, Janet, Earl, Helena, Falzon, Mary, Francis, Adele, Hall, Peter, Harmer, Victoria, Higgins, Helen, Hiller, Louise, Hughes-Davies, Luke, Hulme, Claire, Macpherson, Iain, Makris, Andreas, Marshall, Andrea, McCabe, Christopher, Morgan, Adrienne, Pinder, Sarah, Poole, Christopher, Provenzano, Elena, Rea, Daniel, Stallard, Nigel, Avery, Kerry NL., Barham, C Paul, Berrisford, Richard, Elliott, Jackie, Falk, Stephen J., Goldin, Rob, Hanna, George, Hollowood, Andrew A., Krysztopik, Richard, Metcalfe, Chris, Noble, Sian, Sanders, Grant, Streets, Christopher G., Titcomb, Dan R., and Wheatley, Tim
- Subjects
Clinical trial ,Qualitative research ,Communication ,Randomized Controlled Trial ,Recruitment ,Training healthcare professionals - Abstract
ObjectiveTo evaluate the impact of the Quintet Recruitment Intervention (QRI) on recruitment in challenging randomized controlled trials (RCTs) that have applied the intervention. The QRI aims to understand recruitment difficulties, and then implements ‘QRI-actions’ to address these as recruitment proceeds.Study Design and SettingA mixed-methods study, comprising: a) before-and-after comparisons of recruitment rates and numbers of patients approached, and b) qualitative case studies, including documentary analysis and interviews with RCT investigators.ResultsFive UK-based publicly-funded RCTs were included in the evaluation. All recruited to target. RCT2 and RCT5 both received up-front pre-recruitment training before the intervention was applied. RCT2 did not encounter recruitment issues and recruited above target from its outset. Recruitment difficulties, particularly communication issues, were identified and addressed through QRI-actions in RCTs 1, 3, 4 and 5. Randomization rates significantly improved post-QRI-action in RCTs 1,3, and 4. QRI-actions addressed issues with approaching eligible patients in RCTs 3 and 5, which both saw significant increases in patients approached. Trial investigators reported that the QRI had unearthed issues they had been unaware of, and reportedly changed their practices post QRI-action.ConclusionThere is promising evidence to suggest the QRI can support recruitment to difficult RCTs. This needs to be substantiated with future controlled evaluations.
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- 2019
30. Patch-augmented rotator cuff surgery (PARCS) study-protocol for a feasibility study
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Cook, Jonathan A, Merritt, Naomi, Rees, Jonathan L, Crocker, Joanna C, Hopewell, Sally, Dritsaki, Melina, Beard, David J, Rangan, Amar, Cooper, Cushla, Kottam, Lucksy, Farrar-Hockley, Dair, Thomas, Michael, Earle, Robert, and Carr, Andrew J
- Abstract
Background: A rotator cuff tear is a common disabling shoulder problem. Symptoms include pain, weakness, lack of shoulder mobility and sleep disturbance. Many patients require surgery to repair the tear; however, there is a high failure rate. There is a pressing need to improve the outcome of rotator cuff surgery and the use of patch augmentation to provide support to the healing process and improve patient outcomes holds new promise. Patches have been made using different materials (e.g. human/animal skin or intestine tissue, and completely synthetic materials) and processes (e.g. woven or a mesh). However, clinical evidence on their use is limited. The aim of the patch-augmented rotator cuff surgery (PARCS) feasibility study is to determine, using a mixed method approach, the design of a definitive randomised trial assessing the effectiveness and cost-effectiveness of a patch to augment surgical repair of the rotator cuff that is both acceptable to stakeholders and feasible. Methods: The objectives of this six-stage mixed methods feasibility study are to determine current practice, evidence and views about patch use; achieve consensus on the design of a randomised trial to evaluate patch-augmented rotator cuff surgery; and assess the acceptability and feasibility of the proposed design. The six stages will involve a systematic review of clinical evidence, two surveys of surgeons, focus groups and interviews with stakeholders, a Delphi study and a consensus meeting. The various stakeholders (including patients, surgeons, and representatives from industry, the NHS and regulatory bodies) will be involved across the six stages. Discussion: The PARCS feasibility study will inform the feasibility and acceptability of a randomised trial of the effectiveness and cost-effectiveness of a patch-augmented rotator cuff surgery. Consensus opinion on the basic design of a randomised trial will be sought. Trial registration: Not applicable.
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- 2018
31. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial
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Beard, David J, primary, Davies, Loretta J, additional, Cook, Jonathan A, additional, MacLennan, Graeme, additional, Price, Andrew, additional, Kent, Seamus, additional, Hudson, Jemma, additional, Carr, Andrew, additional, Leal, Jose, additional, Campbell, Helen, additional, Fitzpatrick, Ray, additional, Arden, Nigel, additional, Murray, David, additional, Campbell, Marion K, additional, Barker, Karen, additional, Murray, Gordon, additional, Simpson, Hamish, additional, Dodwell, Donna, additional, Donell, Simon, additional, Waite, Jonathan, additional, Beard, David, additional, Cooper, Cushla, additional, Davies, Loretta, additional, Doll, Helen, additional, Cook, Jonathan, additional, Campbell, Marion, additional, Fernie, Gordon, additional, McDonald, Alison, additional, Duncan, Anne, additional, Castillo, Mayret, additional, Fusco, Francesco, additional, Greshon, Akiko, additional, Holland, Kay, additional, Li, Jiyang, additional, Rabaiotti, Elena, additional, Regan, Sandra, additional, Stalker, Victoria, additional, Forrest, Mark, additional, McPherson, Gladys, additional, Boachie, Charles, additional, Collins, Diana, additional, Cruden, Janice, additional, Halpin, Sophie, additional, Smith, Beverley, additional, Torgerson, David, additional, Maher, Chris, additional, Brownson, Peter, additional, Mullins, Mark Mullins, additional, Blazeby, Jane, additional, Jenkins, Ruth, additional, Lewis, Mark, additional, Mintowt-Czyz, Witek, additional, Beverland, Beverland, additional, Bryce, Leeann, additional, Catney, Julie, additional, Dobie, Ian, additional, Doran, Emer, additional, O'Brien, Seamus, additional, Ali, Fazal, additional, Cripps, Heather, additional, Whileman, Amanda, additional, Williams, Phil, additional, Toms, Julie, additional, Brown, Ellen, additional, Horner, Gillian, additional, Jennings, Andrew, additional, Rose, Glynis, additional, Bamford, Frances, additional, Goddard, Wendy, additional, Marynissen, Hans, additional, Peel, Haleh, additional, Richards, Lyndsey, additional, Bell, Amanda, additional, Deo, Sunny, additional, Grayland, Sarah, additional, Hollinghurst, David, additional, Pegler, Suzannah, additional, Satish, Venkat, additional, Woodruffe, Claire, additional, London, Nick, additional, Duffy, David, additional, Bennett, Caroline, additional, Featherstone, James, additional, Cook, Joss, additional, Dearnley, Kim, additional, Muthukumar, Nagarajan, additional, Onuoha, Laura, additional, Wilson, Sarah, additional, Banher, Sandhu, additional, Emeakaroha, Eunice, additional, Horohan, Jamie, additional, Jain, Sunil, additional, Thompson, Susan, additional, Buckley, Sarah, additional, Ng, Aaron, additional, Shetty, Ajit, additional, Simeson, Karen, additional, Flynn, Julian, additional, Newsom, Meryl, additional, Padilla-Harris, Cheryl, additional, Pearce, Oliver, additional, Bidwell, James, additional, Innes, Alison, additional, Culley, Winifred, additional, Ledingham, Bill, additional, Stephen, Janis, additional, Bray, Rachel, additional, Davies, Hywel, additional, Delgado, Debbie, additional, Eldridge, Jonathan, additional, Morrison, Leigh, additional, Murray, James, additional, Porteous, Andrew, additional, Robinson, James, additional, Dawson, Matt, additional, Dharmarajan, Raj, additional, Elson, David, additional, Hage, Will, additional, Kelsall, Nicci, additional, Orr, Mike, additional, Grosvenor, Jackie, additional, Maheswaran, SS, additional, McCue, Claire, additional, Venkatesh, Hemanth, additional, Wild, Michelle, additional, Wilson, Deborah, additional, Dodd, Chris, additional, Jackson, William, additional, Lovegrove, Pam, additional, Piper, Jennifer, additional, Bradbury, Neil, additional, Clark, Lucy, additional, Duncan, Stefanie, additional, Simpson, Genevieve, additional, Trezies, Allister, additional, Desai, Vikram, additional, Heeley, Cheryl, additional, Guy, Kramer, additional, Jackson, Rosalyn, additional, Hall, Alan, additional, Higgins, Gordon, additional, Hockings, Michael, additional, Isaac, David, additional, Mercer, Pauline, additional, Barber, Lindsey, additional, Cochrane, Helen, additional, Curtis, Janette, additional, Grindey, Julie, additional, Johnson, David, additional, Turner, Phil, additional, Houlihan-Burne, David, additional, Hill, Briony, additional, Langstaff, Ron, additional, Nasseri, Mariam, additional, Bowditch, Mark, additional, Martin, Chris, additional, Pryke, Steven, additional, Purewal, Bally, additional, Servant, Chris, additional, Suresh, Sheeba, additional, Tricker, Claire, additional, Ashford, Robert, additional, Attwal, Manjit, additional, Bunga, Jeanette, additional, Chatterji, Urjit, additional, Cockburn, Susan, additional, Esler, Colin, additional, Godsiff, Steven, additional, Green, Tim, additional, Haines, Christina, additional, Tandon, Subash, additional, Carpio, Racquel, additional, Griffiths, Sarah, additional, Grocott, Natalie, additional, dos Remedios, Ian, additional, Barrett, David, additional, Chapman-Sheath, Phil, additional, Grabau, Caroline, additional, Moghul, Jane, additional, Tice, William, additional, Trevithick, Catherine, additional, Deshmukh, Rajiv, additional, Howes, Mandy, additional, Netherton, Kimberley, additional, Raj, Dipak, additional, Travis, Nikki, additional, Maqsood, Mohammad, additional, Norton, Rebecca, additional, Rashid, Farzana, additional, Raynor, Alison, additional, Rowsell, Mark, additional, and Warner, Karen, additional
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- 2019
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32. The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
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Rooshenas, Leila, primary, Scott, Lauren J., additional, Blazeby, Jane M., additional, Rogers, Chris A., additional, Tilling, Kate M., additional, Husbands, Samantha, additional, Conefrey, Carmel, additional, Mills, Nicola, additional, Stein, Robert C., additional, Metcalfe, Chris, additional, Carr, Andrew J., additional, Beard, David J., additional, Davis, Tim, additional, Paramasivan, Sangeetha, additional, Jepson, Marcus, additional, Avery, Kerry, additional, Elliott, Daisy, additional, Wilson, Caroline, additional, Donovan, Jenny L., additional, Andrews, Robert, additional, Byrne, James, additional, Kelly, Jamie, additional, Mazza, Graziella, additional, Mahon, David, additional, Noble, Hamish, additional, Reeves, Barnaby C., additional, Thompson, Janice L., additional, Wordsworth, Sarah, additional, Welbourn, Richard, additional, Beard, David, additional, Carr, Andrew, additional, Cook, Jonathan, additional, Cooper, Cushla, additional, Dean, Benjamin, additional, Gray, Alastair, additional, Gwilym, Stephen, additional, Judge, Andrew, additional, Merritt, Naomi, additional, Moser, Jane, additional, Rees, Jonathan, additional, Rombach, Ines, additional, Savulescu, Julian, additional, Tracey, Irene, additional, Wartolowska, Karolina, additional, Harrison, Eleanor, additional, Tan, Wei, additional, Karantana, Alexia, additional, Sprange, Kirsty, additional, Duley, Lelia, additional, Hollingworth, William, additional, Montgomery, Alan A., additional, Stein, Rob, additional, Bartlett, John, additional, Cameron, David, additional, Campbell, Amy, additional, Canney, Peter, additional, Dunn, Janet, additional, Earl, Helena, additional, Falzon, Mary, additional, Francis, Adele, additional, Hall, Peter, additional, Harmer, Victoria, additional, Higgins, Helen, additional, Hiller, Louise, additional, Hughes-Davies, Luke, additional, Hulme, Claire, additional, Macpherson, Iain, additional, Makris, Andreas, additional, Marshall, Andrea, additional, McCabe, Christopher, additional, Morgan, Adrienne, additional, Pinder, Sarah, additional, Poole, Christopher, additional, Provenzano, Elena, additional, Rea, Daniel, additional, Stallard, Nigel, additional, Avery, Kerry N.L., additional, Barham, C. Paul, additional, Berrisford, Richard, additional, Elliott, Jackie, additional, Falk, Stephen J., additional, Goldin, Rob, additional, Hanna, George, additional, Hollowood, Andrew A., additional, Krysztopik, Richard, additional, Noble, Sian, additional, Sanders, Grant, additional, Streets, Christopher G., additional, Titcomb, Dan R., additional, and Wheatley, Tim, additional
- Published
- 2019
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33. Oral versus Intravenous Antibiotics for Bone and Joint Infection
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Li, Ho-Kwong, primary, Rombach, Ines, additional, Zambellas, Rhea, additional, Walker, A. Sarah, additional, McNally, Martin A., additional, Atkins, Bridget L., additional, Lipsky, Benjamin A., additional, Hughes, Harriet C., additional, Bose, Deepa, additional, Kümin, Michelle, additional, Scarborough, Claire, additional, Matthews, Philippa C., additional, Brent, Andrew J., additional, Lomas, Jose, additional, Gundle, Roger, additional, Rogers, Mark, additional, Taylor, Adrian, additional, Angus, Brian, additional, Byren, Ivor, additional, Berendt, Anthony R., additional, Warren, Simon, additional, Fitzgerald, Fiona E., additional, Mack, Damien J.F., additional, Hopkins, Susan, additional, Folb, Jonathan, additional, Reynolds, Helen E., additional, Moore, Elinor, additional, Marshall, Jocelyn, additional, Jenkins, Neil, additional, Moran, Christopher E., additional, Woodhouse, Andrew F., additional, Stafford, Samantha, additional, Seaton, R. Andrew, additional, Vallance, Claire, additional, Hemsley, Carolyn J., additional, Bisnauthsing, Karen, additional, Sandoe, Jonathan A.T., additional, Aggarwal, Ila, additional, Ellis, Simon C., additional, Bunn, Deborah J., additional, Sutherland, Rebecca K., additional, Barlow, Gavin, additional, Cooper, Cushla, additional, Geue, Claudia, additional, McMeekin, Nicola, additional, Briggs, Andrew H., additional, Sendi, Parham, additional, Khatamzas, Elham, additional, Wangrangsimakul, Tri, additional, Wong, T.H. Nicholas, additional, Barrett, Lucinda K., additional, Alvand, Abtin, additional, Old, C. Fraser, additional, Bostock, Jennifer, additional, Paul, John, additional, Cooke, Graham, additional, Thwaites, Guy E., additional, Bejon, Philip, additional, and Scarborough, Matthew, additional
- Published
- 2019
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34. Tissue inflammation signatures point towards resolution in adhesive capsulitis
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Dakin, Stephanie Georgina, primary, Rangan, Amar, additional, Martinez, Fernando, additional, Brealey, Stephen, additional, Northgraves, Matthew, additional, Kottam, Lucksy, additional, Cooper, Cushla, additional, Buckley, Christopher Dominic, additional, and Carr, Andrew Jonathan, additional
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- 2019
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35. Surgical treatment of paediatric nail bed injuries in the United Kingdom: Surgeon and patient priorities for future research
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Acquaah, Frank, Afzal, Sadia, Ali, Shirwa Sheik, Beard, David, Bisarya, Kamal, Bruce, David, Cook, Jonathan, Cooper, Cushla, Farrar, Nicola, Furniss, Dominic, Jeyakumar, Jenifa, Horwitz, Max, Lloyd-Hughes, Hawys, Pease, Natalie, McArthur, Gordon, Murphy, Adrian, Ruston, Julia, Soueid, Hassan, Tare, Makarand, Tejero, Ricardo, Theodorakopoulou, Evgenia, Zweifel, Claire, Sierakowski, A., Gardiner, M.D., Jain, A., and Greig, A.V.
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- 2016
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36. An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
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Jepson, Marcus, primary, Elliott, Daisy, additional, Conefrey, Carmel, additional, Wade, Julia, additional, Rooshenas, Leila, additional, Wilson, Caroline, additional, Beard, David, additional, Blazeby, Jane M., additional, Birtle, Alison, additional, Halliday, Alison, additional, Stein, Rob, additional, Donovan, Jenny L., additional, Carr, Andrew, additional, Cook, Jonathan, additional, Cooper, Cushla, additional, Dean, Benjamin, additional, Gray, Alastair, additional, Gwilym, Stephen, additional, Judge, Andrew, additional, Merritt, Naomi, additional, Moser, Jane, additional, Rees, Jonathan, additional, Rombach, Ines, additional, Savulescu, Julian, additional, Tracey, Irene, additional, Wartolowska, Karolina, additional, Barham, Paul, additional, Brookes, Sara T., additional, Crosby, Tom, additional, Falk, Stephen J., additional, Griffin, S. Michael, additional, Hollingworth, William, additional, Hollowood, Andrew D., additional, Krysztopik, Richard, additional, Lewis, Wyn, additional, Nicklin, Jo, additional, Streets, Christopher, additional, Strong, Sean, additional, Titcomb, Dan, additional, Williams, Geraint, additional, Bryan, Rik, additional, Catto, James, additional, Chester, John, additional, French, Ann, additional, Hall, Emma, additional, Harris, Chris, additional, Johnson, Mark, additional, Jones, Rob, additional, Keeley, Francis, additional, Kirkbank, Tony, additional, Kockelbergh, Roger, additional, Lewis, Rebecca, additional, Newton, Michelle, additional, Powles, Thomas, additional, Waters, Rachel, additional, Winterbottom, Andrew, additional, Becquemin, Jean-Pierre, additional, Belli, Anna, additional, Bosiers, Marc, additional, Cao, Piergiorgio, additional, Davies, Christina, additional, Gough, Michael, additional, Hayter, Elizabeth, additional, Leopold, Peter, additional, McDonald, Sumaira, additional, Michaels, Jonathan, additional, Mihaylova, Borislava, additional, Peto, Richard, additional, Robertson, Steven, additional, Rothwell, Peter, additional, Scott, Rachael, additional, Thomas, Dafydd, additional, Vermassen, Frank, additional, Bartlett, John, additional, Cameron, David, additional, Campbell, Amy, additional, Canney, Peter, additional, Dunn, Janet, additional, Earl, Helena, additional, Falzon, Mary, additional, Francis, Adele, additional, Hall, Peter, additional, Harmer, Victoria, additional, Higgins, Helen, additional, Hiller, Louise, additional, Hughes-Davies, Luke, additional, Hulme, Claire, additional, Macpherson, Iain, additional, Makris, Andreas, additional, Marshall, Andrea, additional, McCabe, Christopher, additional, Morgan, Adrienne, additional, Pinder, Sarah, additional, Poole, Christopher, additional, Rea, Daniel, additional, and Stallard, Nigel, additional
- Published
- 2018
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37. Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
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Beard, David J, primary, Rees, Jonathan L, additional, Cook, Jonathan A, additional, Rombach, Ines, additional, Cooper, Cushla, additional, Merritt, Naomi, additional, Shirkey, Beverly A, additional, Donovan, Jenny L, additional, Gwilym, Stephen, additional, Savulescu, Julian, additional, Moser, Jane, additional, Gray, Alastair, additional, Jepson, Marcus, additional, Tracey, Irene, additional, Judge, Andrew, additional, Wartolowska, Karolina, additional, Carr, Andrew J, additional, Ahrens, Philip, additional, Baldwick, Cheryl, additional, Brinsden, Mark, additional, Brownlow, Harry, additional, Burton, David, additional, Butt, Muhammad Sohail, additional, Carr, Andrew, additional, Charalambous, Charalambos P, additional, Conboy, Veronica, additional, Dennell, Lucy, additional, Donaldson, Oliver, additional, Drew, Steven, additional, Dwyer, Amitabh, additional, Gidden, David, additional, Hallam, Peter, additional, Kalogrianitis, Socrates, additional, Kelly, Cormac, additional, Kulkarni, Rohit, additional, Matthews, Tim, additional, McBirnie, Julie, additional, Patel, Vipul, additional, Peach, Chris, additional, Roberts, Chris, additional, Robinson, David, additional, Rosell, Philip, additional, Rossouw, Dan, additional, Senior, Colin, additional, Singh, Bijayendra, additional, Sjolin, Soren, additional, Taylor, Geoffrey, additional, Venkateswaran, Balachandran, additional, and Woods, David, additional
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- 2018
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38. United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial
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Brealey, Stephen, primary, Armstrong, Alison L., additional, Brooksbank, Andrew, additional, Carr, Andrew Jonathan, additional, Charalambous, Charalambos P., additional, Cooper, Cushla, additional, Corbacho, Belen, additional, Dias, Joseph, additional, Donnelly, Iona, additional, Goodchild, Lorna, additional, Hewitt, Catherine, additional, Keding, Ada, additional, Kottam, Lucksy, additional, Lamb, Sarah E., additional, McDaid, Catriona, additional, Northgraves, Matthew, additional, Richardson, Gerry, additional, Rodgers, Sara, additional, Shah, Sarwat, additional, Sharp, Emma, additional, Spencer, Sally, additional, Torgerson, David, additional, Toye, Francine, additional, and Rangan, Amar, additional
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- 2017
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39. United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial
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Brealey, Stephen, Armstrong, Alison L., Brooksbank, Andrew, Carr, Andrew Jonathan, Charalambous, Charalambos P., Cooper, Cushla, Corbacho, Belen, Dias, Joseph, Donnelly, Iona, Goodchild, Lorna, Hewitt, Catherine, Keding, Ada, Kottam, Lucksy, Lamb, Sarah E., McDaid, Catriona, Northgraves, Matthew, Richardson, Gerry, Rodgers, Sarah, Shah, Sarwat, Sharp, Emma, Spencer, Sally, Torgerson, David, Toye, Francine, Rangan, Amar, Brealey, Stephen, Armstrong, Alison L., Brooksbank, Andrew, Carr, Andrew Jonathan, Charalambous, Charalambos P., Cooper, Cushla, Corbacho, Belen, Dias, Joseph, Donnelly, Iona, Goodchild, Lorna, Hewitt, Catherine, Keding, Ada, Kottam, Lucksy, Lamb, Sarah E., McDaid, Catriona, Northgraves, Matthew, Richardson, Gerry, Rodgers, Sarah, Shah, Sarwat, Sharp, Emma, Spencer, Sally, Torgerson, David, Toye, Francine, and Rangan, Amar
- Abstract
Background: Frozen shoulder (also known as adhesive capsulitis) occurs when the capsule, or the soft tissue envelope around the ball and socket shoulder joint, becomes scarred and contracted, making the shoulder tight, painful and stiff. It affects around 1 in 12 men and 1 in 10 women of working age. Although this condition can settle with time (typically taking 1 to 3 years), for some people it causes severe symptoms and needs referral to hospital. Our aim is to evaluate the clinical and cost-effectiveness of two invasive and costly surgical interventions that are commonly used in secondary care in the National Health Service (NHS) compared with a non-surgical comparator of Early Structured Physiotherapy. Methods: We will conduct a randomised controlled trial (RCT) of 500 adult patients with a clinical diagnosis of frozen shoulder, and who have radiographs that exclude other pathology. Early Structured Physiotherapy with an intra-articular steroid injection will be compared with manipulation under anaesthesia with a steroid injection or arthroscopic (keyhole) capsular release followed by manipulation. Both surgical interventions will be followed with a programme of post-procedural physiotherapy. These treatments will be undertaken in NHS hospitals across the United Kingdom. The primary outcome and endpoint will be 3 / 7 the Oxford Shoulder Score (a patient selfreported assessment of shoulder function) at 12 months. This will also be measured at baseline, 3 and 6 months after randomisation; and on the day that treatment starts and 6 months later. Secondary outcomes include the Disabilities of Arm Shoulder and Hand (Quick DASH) score, the EQ-5D-5 L score, pain, extent of recovery and complications.We will explore the acceptability of the different treatments to patients and health care professionals using qualitative methods. Discussion: The three treatments being compared are the most frequently used in secondary care in the NHS, but there is uncertainty about which
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- 2017
40. Increasing age and tear size reduce rotator cuff repair healing rate at 1 year
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Rashid, Mustafa S, primary, Cooper, Cushla, additional, Cook, Jonathan, additional, Cooper, David, additional, Dakin, Stephanie G, additional, Snelling, Sarah, additional, and Carr, Andrew J, additional
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- 2017
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41. Injection versus Decompression for Carpal Tunnel Syndrome-Pilot trial (INDICATE-P)—protocol for a randomised feasibility study
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Mason, Will, primary, Ryan, Daniel, additional, Khan, Asif, additional, Kerr, Hui-Ling, additional, Beard, David, additional, Cook, Jonathan, additional, Rombach, Ines, additional, and Cooper, Cushla, additional
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- 2017
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42. The CSAW Study (Can Shoulder Arthroscopy Work?) – a placebo-controlled surgical intervention trial assessing the clinical and cost effectiveness of arthroscopic subacromial decompression for shoulder pain: study protocol for a randomised controlled trial
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Beard, David, Rees, Jonathan, Rombach, Ines, Cooper, Cushla, Cook, Jonathan, Merritt, Naomi, Gray, Alastair, Gwilym, Stephen, Judge, Andrew, Savulescu, Julian, Moser, Jane, Donovan, Jenny, Jepson, Marcus, Wilson, Caroline, Tracey, Irene, Wartolowska, Karolina, Dean, Benjamin, Carr, Andrew, Jones, Anthony, Rangan, Amar, Hutchinson, James, Conboy, Veronica, Costa, Matthew, Stanton, Louise, Brealey, Stephen, and Bowers, Megan
- Subjects
Male ,Time Factors ,Cost effectiveness ,Decompression ,Cost-Benefit Analysis ,Waiting list ,Medicine (miscellaneous) ,Trial ,law.invention ,Study Protocol ,Arthroscopy ,Postoperative Complications ,Randomized controlled trial ,Clinical Protocols ,law ,Pharmacology (medical) ,Randomise ,Pain Measurement ,medicine.diagnostic_test ,Osteophyte ,Health Care Costs ,Decompression, Surgical ,Intention to Treat Analysis ,medicine.anatomical_structure ,Treatment Outcome ,Centre for Surgical Research ,Patient Satisfaction ,Research Design ,Female ,Acromion ,musculoskeletal diseases ,medicine.medical_specialty ,Shoulder ,Placebo ,Sham ,Predictive Value of Tests ,Shoulder Pain ,medicine ,Humans ,Rotator cuff ,Intention-to-treat analysis ,business.industry ,United Kingdom ,Surgery ,Sample Size ,Physical therapy ,business - Abstract
Background Arthroscopic subacromial decompression (ASAD) is a commonly performed surgical intervention for shoulder pain. The rationale is that removal of a bony acromial spur relieves symptoms by decompressing rotator cuff tendons passing through the subacromial space. However, the efficacy of this procedure is uncertain. The objective of this trial was to compare the efficacy and cost-effectiveness of ASAD in patients with subacromial pain using appropriate control groups, including placebo intervention. Methods/Design The trial is a three-group, parallel design, pragmatic, randomised controlled study. The intervention content for each group (ASAD, active monitoring with specialist reassessment (AMSR) and investigational shoulder arthroscopy only (AO)) enables assessment of (1) the efficacy of the surgery against no surgery; (2) the need for a specific component of the surgery—namely, removal of the bony spur; and (3) quantification of the placebo effect. Concealed allocation was performed using a 1:1:1 randomisation ratio and using age, sex, baseline Oxford Shoulder Score (OSS) and centre as minimisation criteria. The primary outcome measure is the OSS at 6 months post randomisation. A total of 300 patients recruited over 24 months from a minimum of 14 UK shoulder units over 24 months were required to detect a difference of 4.5 points on the OSS (standard deviation, 9) with 90% power and to allow for 15% loss to follow-up. Secondary outcomes include cost-effectiveness, pain, complications and patient satisfaction. A substantial qualitative research component is included. The primary analysis will be conducted on the modified intention-to-treat analysis. Sensitivity analysis will be used to assess the robustness of the results with regard to the underlying assumptions about missing data using multiple imputation. Discussion This trial uses an innovative design to account for the known placebo effects of surgery, but it also will delineate the mechanism for any benefit from surgery. The investigational AO group is considered a placebo intervention (not sham surgery), as it includes all components of subacromial decompression except the critical surgical element. Some discussion is also dedicated to the challenges of conducting placebo surgery trials. Trial registrations UK Clinical Research Network UKCRN12104. Registered 22 May 2012. International Standard Randomised Controlled Trial ISRCTN33864128. Registered 22 June 2012. ClinicalTrials.gov NCT01623011. Registered 15 June 2012. Electronic supplementary material The online version of this article (doi:10.1186/s13063-015-0725-y) contains supplementary material, which is available to authorized users.
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- 2015
43. Steroid injection versus surgical decompression for carpal tunnel syndrome
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Cooper, Cushla, primary
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- 2016
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44. Surgical treatment of paediatric nail bed injuries in the United Kingdom: Surgeon and patient priorities for future research
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Sierakowski, A., primary, Gardiner, M.D., additional, Jain, A., additional, Greig, A.V., additional, Acquaah, Frank, additional, Afzal, Sadia, additional, Ali, Shirwa Sheik, additional, Beard, David, additional, Bisarya, Kamal, additional, Bruce, David, additional, Cook, Jonathan, additional, Cooper, Cushla, additional, Farrar, Nicola, additional, Furniss, Dominic, additional, Jeyakumar, Jenifa, additional, Horwitz, Max, additional, Lloyd-Hughes, Hawys, additional, Pease, Natalie, additional, McArthur, Gordon, additional, Murphy, Adrian, additional, Ruston, Julia, additional, Soueid, Hassan, additional, Tare, Makarand, additional, Tejero, Ricardo, additional, Theodorakopoulou, Evgenia, additional, and Zweifel, Claire, additional
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- 2016
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45. Oral versus intravenous antibiotic treatment for bone and joint infections (OVIVA): study protocol for a randomised controlled trial
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Li, Ho Kwong, primary, Scarborough, Matthew, additional, Zambellas, Rhea, additional, Cooper, Cushla, additional, Rombach, Ines, additional, Walker, A. Sarah, additional, Lipsky, Benjamin A., additional, Briggs, Andrew, additional, Seaton, Andrew, additional, Atkins, Bridget, additional, Woodhouse, Andrew, additional, Berendt, Anthony, additional, Byren, Ivor, additional, Angus, Brian, additional, Pandit, Hemant, additional, Stubbs, David, additional, McNally, Martin, additional, Thwaites, Guy, additional, and Bejon, Philip, additional
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- 2015
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46. Clinical effectiveness and cost-effectiveness of open and arthroscopic rotator cuff repair [the UK Rotator Cuff Surgery (UKUFF) randomised trial]
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Carr, Andrew J, primary, Cooper, Cushla D, additional, Campbell, Marion K, additional, Rees, Jonathan L, additional, Moser, Jane, additional, Beard, David J, additional, Fitzpatrick, Ray, additional, Gray, Alastair, additional, Dawson, Jill, additional, Murphy, Jacqueline, additional, Bruhn, Hanne, additional, Cooper, David, additional, and Ramsay, Craig R, additional
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- 2015
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47. Nail bed INJury Assessment Pilot (NINJA-P) study: should the nail plate be replaced or discarded after nail bed repair in children? Study protocol for a pilot randomised controlled trial
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Jain, Abhilash, primary, Sierakowski, Adam, additional, Gardiner, Matthew D., additional, Beard, David, additional, Cook, Jonathan, additional, Cooper, Cushla, additional, and Greig, Aina, additional
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- 2015
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48. Accounting for the placebo effect of surgery in surgical trials?
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Beard, David, primary, Cooper, Cushla, additional, Rombach, Ines, additional, Rees, Jon, additional, Wartolowska, Karolina, additional, Cummings, Naomi, additional, and Carr, Andrew, additional
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- 2013
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49. What influences surgeons’ experience of surgical research?
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Cooper, Cushla, primary, Beard, David, additional, and Carr, Andrew, additional
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- 2013
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50. Challenges in the design and analysis of surgical trials
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Rombach, Ines, primary, Beard, David, additional, Carr, Andrew, additional, Rees, Jonathan, additional, Cooper, Cushla, additional, and Cummings, Naomi, additional
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- 2013
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