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1. Nirmatrelvir-ritonivir, COVID-19, and possible adverse cutaneous reactions

Author

Albrecht, J Mark, Cooper, Benjamin R, Waller, Jacquelyn D, Presley, Colby L, Pulsipher, Kayd J, Rundle, Chandler W, and Dellavalle, Robert P

Subjects
COVID-19, cutaneous, drug reactions, nirmatrelvir-ritonivir, paxlovid, protease inhibitors
Abstract

Nirmatrelvir-ritonivir (Paxlovid) recently received emergency use authorization for the treatment of coronavirus disease 2019 (COVID-19). Literature has linked numerous cutaneous adverse effects to nirmatrelvir and ritonavir, the copackaged tablets within Paxlovid. A review and comparison of these adverse effects to the common cutaneous manifestations of COVID-19 is provided. Numerous drug-to-drug interactions exist between nirmatrelvir-ritonivir and commonly-used medications within dermatology.

Published
2023

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