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23 results on '"Cooney, Tabitha M"'

1. Automated temporalis muscle quantification and growth charts for children through adulthood

Author

Zapaishchykova, Anna, Liu, Kevin X., Saraf, Anurag, Ye, Zezhong, Catalano, Paul J., Benitez, Viviana, Ravipati, Yashwanth, Jain, Arnav, Huang, Julia, Hayat, Hasaan, Likitlersuang, Jirapat, Vajapeyam, Sridhar, Chopra, Rishi B., Familiar, Ariana M., Nabavidazeh, Ali, Mak, Raymond H., Resnick, Adam C., Mueller, Sabine, Cooney, Tabitha M., Haas-Kogan, Daphne A., Poussaint, Tina Y., Aerts, Hugo J.W.L., and Kann, Benjamin H.

Published
2023
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6. Sexual health in adult survivors of childhood cancer: A Project REACH study.

Author

Chevalier, Lydia L., McCormick, Katherine, Cooney, Tabitha M., Recklitis, Christopher J., and Bober, Sharon L.

Subjects
SEXUAL dysfunction, MEDICAL screening, CENTRAL nervous system, SEXUAL health, CANCER survivors, CENTRAL nervous system tumors
Abstract

Background: Sexual dysfunction is a significant complication of treatment for many adult‐onset cancers. However, comparatively less is known about sexual dysfunction in adult childhood cancer survivors (CCSs). Research has been limited by the exclusion of specific cancers (e.g., central nervous system [CNS] tumors) and the lack of validated measures, which makes it difficult to understand the nature and prevalence of sexual dysfunction in CCSs. Methods: A total of 249 adult CCSs (aged 18–65 years) enrolled in Project REACH, a prospective cohort study, and completed measures of physical and mental health, including sexual dysfunction. Participants scoring ≤19 on the Female Sexual Function Index 6 or ≤21 on the International Index of Erectile Function 5 were classified as experiencing sexual dysfunction. Analyses examined the relationships between sexual dysfunction and demographic, disease, treatment, and health variables. Results: A total of 78 participants (32%) experienced clinically significant sexual dysfunction. In univariate analysis, sexual dysfunction was significantly associated with CNS tumor diagnosis (odds ratio [OR], 2.56) and surgery (OR, 1.96) as well as with health variables such as fatigue (OR, 3.00), poor sleep (OR, 2.84), pain (OR, 2.04), depression (OR, 2.64), poor physical health (OR, 2.45), and poor mental health (OR, 2.21). Adjusted analyses found that CNS tumor diagnosis (p =.001) and health variables (p =.025) contribute significantly to sexual dysfunction in CCSs. Conclusions: Approximately one third of adult CCSs report clinically significant sexual dysfunction, which underscores a significant screening and treatment need. However, because available measures were developed for survivors of adult cancers, research to create a sexual health measure specifically for adult CCSs is necessary to better identify the sexual health concerns of this vulnerable population. Regular sexual health screening and treatment are necessary because approximately one third of adult childhood cancer survivors (CCSs) experience sexual dysfunction, with central nervous system tumor survivors experiencing particularly high rates. However, because measures were developed for older survivors, a measure specifically designed for CCSs is critical to better identify and describe the sexual health concerns of this vulnerable population. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer

Author

Lazo De La Vega, Lorena, Comeau, Hannah, Sallan, Sarah, Al-Ibraheemi, Alyaa, Gupta, Hersh, Li, Yvonne Y., Tsai, Harrison K., Kang, Wenjun, Ward, Abigail, Church, Alanna J., Kim, AeRang, Pinto, Navin R., Macy, Margaret E., Maese, Luke D., Sabnis, Amit J., Cherniack, Andrew D., Lindeman, Neal I., Anderson, Megan E., Cooney, Tabitha M., Yeo, Kee Kiat, Reaman, Gregory H., DuBois, Steven G., Collins, Natalie B., Johnson, Bruce E., Janeway, Katherine A., and Forrest, Suzanne J.

Published
2022
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11. Integrated response analysis of pediatric low-grade gliomas during and after targeted therapy treatment

Author

Tsai, Jessica W, primary, Choi, Jungwhan John, additional, Ouaalam, Hakim, additional, Murillo, Efrain Aguilar, additional, Yeo, Kee Kiat, additional, Vogelzang, Jayne, additional, Sousa, Cecilia, additional, Woods, Jared K, additional, Ligon, Keith L, additional, Warfield, Simon K, additional, Bandopadhayay, Pratiti, additional, and Cooney, Tabitha M, additional

Published
2022
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13. PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.

Author

Mueller, Sabine, Kline, Cassie, Stoller, Schuyler, Lundy, Shannon, Christopher, Lauren, Reddy, Alyssa T, Banerjee, Anu, Cooney, Tabitha M, Raber, Shannon, Hoffman, Carly, Luks, Tracy, Wembacher-Schroeder, Eva, Lummel, Nina, Zhang, Yalan, Bonner, Erin R, Nazarian, Javad, Molinaro, Annette M, Prados, Michael, Villanueva-Meyer, Javier E, and Gupta, Nalin

Published
2023
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14. The effect of pediatric central nervous system tumors on identity in young adult survivors: a project REACH study.

Author

Cacciotti, Chantel, Chevalier, Lydia Larocque, Medeiros-Nancarrow, Cheryl, Recklitis, Christopher, and Cooney, Tabitha M.

Abstract

Purpose: Of all childhood cancers, adult survivors of pediatric central nervous system (CNS) tumors are at the highest risk for late mortality as well as neurocognitive, physical, and psychosocial late effects. Their identity with cancer survivorship, the relationship of their identity to health outcomes, and how their identity differs from other childhood cancer survivors is poorly understood. Methods: A total of 127 young adults previously treated for pediatric CNS tumors enrolled in Project REACH, a locally-treated childhood cancer survivor cohort. Participants completed self-report measures on the effects of cancer on identity, someone who had cancer, victim and survivor identity, frequency of thoughts of diagnosis, and health outcomes. Results: The majority of participants identified as a survivor (83%). Survivor identity was linked to diagnosis and treatment but not health outcomes. A minority (9%) endorsed a victim identity, and they were more likely to have poorer mental health (p = 0.03) and depression (p = 0.04) than non-victims. Participants who reported a stronger effect of cancer on their identity also had poorer mental health (p = 0.005). A higher frequency of diagnosis-related thoughts was associated with significantly poorer mental health (p < 0.001), more severe anxiety (p = 0.008), depression (p < 0.001), and neurocognitive impairments (p < 0.01). Those who experienced relapse, radiation, and/or chemotherapy were more likely to identify as someone who had cancer, independent of diagnosis. Implications for Cancer Survivors: Our findings suggest the relationships previously reported between identity and sociodemographic, treatment, and health outcomes after adult and pediatric non-CNS cancers cannot be generalized to pediatric CNS tumors. Understanding the unique features of how this population identifies is important for patient-centered care. [ABSTRACT FROM AUTHOR]

Published
2023
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16. LGG-32. Integrated biologic, radiologic and clinical analysis of pediatric low-grade gliomas during and after targeted therapy treatment

Author

Tsai, Jessica W, primary, Choi, Jungwhan John, additional, Ouaalam, Hakim, additional, Murrillo, Efrain Aguilar, additional, Yeo, Kee Kiat, additional, Vogelzang, Jayne, additional, Sousa, Cecilia, additional, Woods, Jared K, additional, Ligon, Keith L, additional, Warfield, Simon K, additional, Bandopadhayay, Pratiti, additional, and Cooney, Tabitha M, additional

Published
2022
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18. Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry

Author

Lazow, Margot A, primary, Fuller, Christine, additional, DeWire, Mariko, additional, Lane, Adam, additional, Bandopadhayay, Pratiti, additional, Bartels, Ute, additional, Bouffet, Eric, additional, Cheng, Sylvia, additional, Cohen, Kenneth J, additional, Cooney, Tabitha M, additional, Coven, Scott L, additional, Dholaria, Hetal, additional, Diez, Blanca, additional, Dorris, Kathleen, additional, El-ayadi, Moatasem, additional, El-Sheikh, Ayman, additional, Fisher, Paul G, additional, Fonseca, Adriana, additional, Garcia Lombardi, Mercedes, additional, Greiner, Robert J, additional, Goldman, Stewart, additional, Gottardo, Nicholas, additional, Gururangan, Sridharan, additional, Hansford, Jordan R, additional, Hassall, Tim, additional, Hawkins, Cynthia, additional, Kilburn, Lindsay, additional, Koschmann, Carl, additional, Leary, Sarah E, additional, Ma, Jie, additional, Minturn, Jane E, additional, Monje-Deisseroth, Michelle, additional, Packer, Roger, additional, Samson, Yvan, additional, Sandler, Eric S, additional, Sevlever, Gustavo, additional, Tinkle, Christopher L, additional, Tsui, Karen, additional, Wagner, Lars M, additional, Zaghloul, Mohamed, additional, Ziegler, David S, additional, Chaney, Brooklyn, additional, Black, Katie, additional, Asher, Anthony, additional, Drissi, Rachid, additional, Fouladi, Maryam, additional, Jones, Blaise V, additional, and Leach, James L, additional

Published
2021
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20. DDRE-32. THERAPEUTIC TARGETING OF A NOVEL METABOLIC ADDICTION IN DIFFUSE MIDLINE GLIOMA

Author

Pal, Sharmistha, primary, Kaplan, Jakub P, additional, Stopka, Sylwia A, additional, Regan, Michael S, additional, Hunsel, Bradley R, additional, Kann, Benjamin H, additional, Agar, Nathalie Y R, additional, Stiles, Charles D, additional, Cooney, Tabitha M, additional, Mueller, Sabine, additional, Chowdhury, Dipanjan, additional, Kaelin, William G, additional, McBrayer, Samuel K, additional, and Haas-Kogan, Daphne, additional

Published
2021
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21. DIPG-46. NON-DIPG PATIENTS ENROLLED IN THE INTERNATIONAL DIPG REGISTRY: HISTOPATHOLOGIC EVALUATION OF CENTRAL NEURO-IMAGING REVIEW

Author

Lazow, Margot A, primary, Fuller, Christine, additional, Lane, Adam, additional, DeWire-Schottmiller, Mariko D, additional, Bandopadhayay, Pratiti, additional, Bartels, Ute, additional, Bouffet, Eric, additional, Cheng, Sylvia, additional, Cohen, Kenneth J, additional, Cooney, Tabitha M, additional, Coven, Scott L, additional, Dholaria, Hetal, additional, Diez, Blanca, additional, Dorris, Kathleen, additional, El-Ayadi, Motasem, additional, El-Sheikh, Ayman, additional, Fisher, Paul G, additional, Lombardi, Mercedes Garcia, additional, Greiner, Robert J, additional, Goldman, Stewart, additional, Gottardo, Nicholas, additional, Gururangan, Sridharan, additional, Hansford, Jordan R, additional, Hassall, Tim, additional, Hawkins, Cynthia, additional, Kilburn, Lindsay, additional, Koschmann, Carl J, additional, Leary, Sarah E, additional, Ma, Jie, additional, Minturn, Jane E, additional, Monje-Deisseroth, Michelle, additional, Packer, Roger J, additional, Samson, Yvan, additional, Sandler, Eric S, additional, Sevlever, Gustavo, additional, Tinkle, Christopher, additional, Tsui, Karen, additional, Wagner, Lars M, additional, Zaghloul, Mohamed, additional, Ziegler, David S, additional, Chaney, Brooklyn, additional, Black, Katie, additional, Asher, Anthony, additional, Drissi, Rachid, additional, Fouladi, Maryam, additional, Jones, Blaise V, additional, and Leach, James L, additional

Published
2020
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23. Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.

Author

Lazow, Margot A, Fuller, Christine, DeWire, Mariko, Lane, Adam, Bandopadhayay, Pratiti, Bartels, Ute, Bouffet, Eric, Cheng, Sylvia, Cohen, Kenneth J, Cooney, Tabitha M, Coven, Scott L, Dholaria, Hetal, Diez, Blanca, Dorris, Kathleen, El-ayadi, Moatasem, El-Sheikh, Ayman, Fisher, Paul G, Fonseca, Adriana, Lombardi, Mercedes Garcia, and Greiner, Robert J

Published
2022
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