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6 results on '"Coomes Rm"'

2. Alkaloids of the papaveraceae. XX. 2,9-Dimethoxy-3-hydroxypavinane, a new alkaloid from Argemone munita subsp. rotundata

Author

Williams Dk, Falck, Frank R. Stermitz, and Coomes Rm

Subjects
Bridged-Ring Compounds, Methyl Ethers, Magnetic Resonance Spectroscopy, Plants, Medicinal, biology, Optical Rotation, Stereochemistry, Chemistry, Alkaloid, Organic Chemistry, biology.organism_classification, Mass Spectrometry, Alkaloids, Argemone munita, Botany, Papaveraceae, Spectrophotometry, Ultraviolet, Papaver
Published
1973

3. Antineoplastic agents. 42. The butterfly, Prioneris thestylis.

Author

Pettit GR, Ode RH, Coomes RM, and Ode SL

Subjects
Animals, Chromatography, Gel, Chromatography, Thin Layer, Guanine isolation & purification, Guanine pharmacology, Hypoxanthines isolation & purification, Methods, Uric Acid isolation & purification, Urocanic Acid isolation & purification, Xanthines isolation & purification, Antineoplastic Agents isolation & purification, Butterflies analysis, Lepidoptera analysis
Abstract

Isoguanine (2) was found to be an antineoplastic constituent of Prioneris thestylis Dbldy. wings. Three other purine components of the butterfly wings were identified as hypoxanthine (3), uric acid (4) and xanthine (5). Isolation of urocanic acid (6) from the same wing material represented the first detection of this interesting histidine derivative in an arthropod.

Published
1976

4. Butterfly wing antineoplastic agents.

Author

Pettit GR, Houghton LE, Rogers NH, Coomes RM, Berger DF, Reucroft PR, Day JF, Hartwell JL, and Wood HB Jr

Subjects
Animals, Chromatography, DEAE-Cellulose, Chromatography, Thin Layer, Neoplasms, Experimental drug therapy, Rats, Xanthopterin therapeutic use, Antineoplastic Agents analysis, Insecta analysis, Wings, Animal analysis, Xanthopterin analysis
Published
1972
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