1. Consumo de huevo y dislipidemia en una cohorte mediterránea.
- Author
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Vázquez-Ruiz, Zenaida, de la Fuente-Arrillaga, Carmen, Bes-Rastrollo, Maira, Zazpe, Itziar, Santiago, Susana, Razquin, Cristina, Toledo, Estefanía, Martínez-González, Miguel Ángel, Vazquez-Ruiz, Zenaida, and Martinez-Gonzalez, Miguel Ángel
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EGGS , *DYSLIPIDEMIA , *FOOD habits , *BLOOD cholesterol , *HIGH density lipoproteins , *TRIGLYCERIDES - Abstract
Introduction and Objectives: Our aim was to prospectively evaluate the association between egg consumption and dyslipidemia in a Mediterranean cohort.Methods: We followed-up 13,104 Spanish university graduates for a mean period of 8 years. Dietary habits at baseline were assessed using a validated semi-quantitative 136-item food-frequency questionnaire. Self-reported blood concentrations of total cholesterol, high-density lipoproteins cholesterol (HDL-c) and triglycerides were evaluated according to categories of egg consumption after 6 and 8 years of follow-up. We also assessed the association between baseline egg consumption and the incidence of hypercholesterolemia, low HDL-c concentrations and hypertriglyceridemia during follow-up.Results: We observed a significant inverse association for intermediate levels of egg consumption (2 to 4 eggs/week vs. less than 1 egg/week) and hypertriglyceridemia with OR = 0.71 (95% confidence interval [CI]: 0.54 to 0.93, p < 0.05) in the multivariable-adjusted model. Using HDL-c values after 8-year follow-up, we found an association between higher egg consumption and lower HDL-c levels (p for trend = 0.02) with an adjusted difference of -4.01 mg/dl (-7.42 to -0.61) for > 4 vs. < 1 egg/week. Lower means of triglycerides were found in each of the three upper categories of egg consumption compared to the lowest category (< 1 egg/week) with significant results for some of these categories both after 6 and 8 year follow-up.Conclusions: Our data do not support that higher egg consumption was associated with abnormal blood levels of total cholesterol or triglycerides; an inverse association with HDL-c as a quantitative variable was found only in one of our analyses. [ABSTRACT FROM AUTHOR]- Published
- 2018
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