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1. C51 INTRAVASCULAR LITHOTRIPSY FOR THE TREATMENT OF SEVERELY CALCIFIED CORONARY STENOSIS IN ACUTE MYOCARDIAL INFARCTION

Author

Pavani, M, primary, Franzè, A, additional, Cinconze, S, additional, Barbero, U, additional, Meliga, E, additional, Rognoni, A, additional, Nicolino, A, additional, Biasco, L, additional, Conrotto, F, additional, Ugo, F, additional, Scacciatella, P, additional, Tomassini, F, additional, Leoncini, M, additional, Menozzi, A, additional, Patti, G, additional, Rolandi, A, additional, Porto, I, additional, Musumeci, G, additional, Cerrato, E, additional, and Varbella, F, additional

Published
2023
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2. Transthyretin cardiac amyloidosis in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement: a single center experience

Author

Scudeler, L, primary, Gallone, G, additional, Bongiovanni, C, additional, Bruno, F, additional, Landra, F, additional, Andreis, A, additional, Fava, A, additional, Pidello, S, additional, Raineri, C, additional, Giorgi, M, additional, D'Ascenzo, F, additional, Conrotto, F, additional, Alunni, G, additional, Rinaldi, M, additional, and De Ferrari, G M, additional

Published
2022
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4. Mid-term prognostic value of coronary artery disease in patients undergoing transcatheter aortic valve implantation: A meta-analysis of adjusted observational results

Author

D'Ascenzo, F., Conrotto, F., Giordana, F., Moretti, C., D'Amico, M., Salizzoni, S., Omedè, P., La Torre, M., Thomas, M., Khawaja, Z., Hildick-Smith, D., Ussia, Gp., Barbanti, M., Tamburino, C., Webb, John, Schnabel, R.B., Seiffert, M., Wilde, S., Treede, H., Gasparetto, V., Napodano, M., Tarantini, G., Presbitero, P., Mennuni, M., Rossi, M.L., Gasparini, M., Biondi Zoccai, G., Lupo, M., Rinaldi, M., Gaita, F., and Marra, S.

Published
2013
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5. Predictors of fractional flow reserve/instantaneous wave-free ratio discordance: impact of tailored diagnostic cut-offs on clinical outcomes of deferred lesions

Author

De Filippo, O., Gallone, G., D'Ascenzo, Francesca, Leone, Antonio Maria, Mancone, M., Quadri, G., Barbieri, Laura, Bossi, I., Boccuzzi, G., Montone, Rocco Antonio, Burzotta, Francesco, Iannaccone, Marco, Montefusco, A., Carugo, S., Castelli, C., Oreglia, J., Cerrato, E., Peirone, A., Zaccardo, G., Sardella, G., Niccoli, Giampaolo, Omede, P., Varbella, F., Rognoni, A., Trani, Carlo, Conrotto, F., Escaned, J., De Ferrari, G. M., D'Ascenzo F., Leone A. M. (ORCID:0000-0002-1276-9883), Barbieri L. (ORCID:0000-0001-9975-9874), Montone R. A., Burzotta F. (ORCID:0000-0002-6569-9401), Iannaccone M., Niccoli G. (ORCID:0000-0002-3187-6262), Trani C. (ORCID:0000-0001-9777-013X), De Filippo, O., Gallone, G., D'Ascenzo, Francesca, Leone, Antonio Maria, Mancone, M., Quadri, G., Barbieri, Laura, Bossi, I., Boccuzzi, G., Montone, Rocco Antonio, Burzotta, Francesco, Iannaccone, Marco, Montefusco, A., Carugo, S., Castelli, C., Oreglia, J., Cerrato, E., Peirone, A., Zaccardo, G., Sardella, G., Niccoli, Giampaolo, Omede, P., Varbella, F., Rognoni, A., Trani, Carlo, Conrotto, F., Escaned, J., De Ferrari, G. M., D'Ascenzo F., Leone A. M. (ORCID:0000-0002-1276-9883), Barbieri L. (ORCID:0000-0001-9975-9874), Montone R. A., Burzotta F. (ORCID:0000-0002-6569-9401), Iannaccone M., Niccoli G. (ORCID:0000-0002-3187-6262), and Trani C. (ORCID:0000-0001-9777-013X)

Abstract

BACKGROUND: Patient-related and lesion-related factors may influence instantaneous wave-free ratio (iFR)/fractional flow reserve (FFR) concordance, potentially affecting the safety of revascularization deferral. METHODS: Consecutive patients with at least an intermediate coronary stenosis evaluated by both iFR and FFR were retrospectively enrolled. The agreement between iFR and FFR at their diagnostic cut-offs (FFR 0.80, iFR 0.89) was assessed. Predictors of discordance were assessed using multivariate analyses. Tailored iFR cut-offs according to predictors of discordance best matching an FFR of 0.80 were identified. The impact of reclassification according to tailored iFR cut-offs on major cardiovascular events (MACE: cardiovascular death, myocardial infarction or target-lesion revascularization) among deferred lesions was investigated. RESULTS: Two hundred and ninety-nine intermediate coronary stenosis [FFR 0.84 (0.78-0.89), iFR 0.91 (0.87-0.95), 202 left main/left anterior descending (LM/LAD) vessels, 67.6%] of 260 patients were studied. Discordance rate was 23.4% (n = 70, 10.7% iFR-negative discordant, 12.7% iFR-positive discordant). Predictors of discordance were LM/LAD disease, multivessel disease, non-ST-elevation myocardial infarction, smoking, reduced eGFR and hypertension. Lesion reclassification with tailored iFR cut-offs based on patient-level predictors carried no prognostic value among deferred lesions. Reclassification according to lesion location, which was entirely driven by LM/LAD lesions (iFR cut-offs: 0.93 for LM/LAD, 0.89 for non-LM/LAD), identified increased MACE among lesions deferred based on a negative FFR, between patients with a positive as compared with a negative iFR (19.4 vs. 6.1%, P = 0.044), whereas the same association was not observed with the conventional 0.89 iFR cut-off (15 vs. 8.6%, P = 0.303). CONCLUSION: Tailored vessel-based iFR cut-offs carry prognostic value among FFR-negative lesions, suggesting that a one-size-fit-all iFR

Published
2022

6. C25 PREDICTION OF ALL–CAUSE MORTALITY FOLLOWING PERCUTANEOUS CORONARY INTERVENTION IN BIFURCATION LESIONS USING MACHINE LEARNING ALGORITHMS – THE RAIN–ML PREDICTION MODEL

Author

Gallone, G, primary, Burrello, J, additional, Burrello, A, additional, Iannaccone, M, additional, De Luca, L, additional, Patti, G, additional, Cerrato, E, additional, Venuti, G, additional, De Filippo, O, additional, Mattesini, A, additional, Muscoli, S, additional, Trabattoni, D, additional, Giammaria, M, additional, Truffa, A, additional, Cortese, B, additional, Conrotto, F, additional, Mulatero, P, additional, Monticone, S, additional, Escaned, J, additional, Usmiani, T, additional, D‘ascenzo, F, additional, De Ferrari, G, additional, and Breviario, S, additional

Published
2022
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7. P316 TRANSTHYRETIN CARDIAC AMYLOIDOSIS IN PATIENTS WITH SEVERE AORTIC STENOSIS UNDERGOING TRANSCATHETER AORTIC VALVE REPLACEMENT: A SINGLE CENTER EXPERIENCE

Author

Gallone, G, primary, Bongiovanni, F, additional, Bruno, F, additional, Scudeler, L, additional, Landra, F, additional, Andreis, A, additional, Casoni, R, additional, Fava, A, additional, Pidello, S, additional, Raineri, C, additional, Usmiani, T, additional, Alunni, G, additional, Conrotto, F, additional, D‘ascenzo, F, additional, and De Ferrari, G, additional

Published
2022
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8. Net clinical benefit of different strategies of dual antiplatelet therapy in elderly patients: Data from the praise registry

Author

D'Ascenzo, F., Elia, E., de Filippo, O., Manai, R., Breviario, S., Bruno, F., Iannaccone, M., Wanha, W., Bianco, M., Patti, G., Raposeiras-Roubin, S., Abu-Assi, E., Bo, M., De Ferrari, G. M., and Conrotto, F.

Subjects
Aged, 80 and over, Ticagrelor, Myocardial Infarction, Acute coronary syndrome, Clopidogrel, Dual antiplatelet therapy, Elderly, Prasugrel, Hemorrhage, Percutaneous Coronary Intervention, Treatment Outcome, Humans, Registries, Acute Coronary Syndrome, Cardiology and Cardiovascular Medicine, Prasugrel Hydrochloride, Platelet Aggregation Inhibitors, Aged
Abstract

The safety and efficacy of potent P2Y12 inhibitors (Ticagrelor and Prasugrel) in dual antiplatelet therapy (DAPT) with aspirin in elderly acute coronary syndrome (ACS) patients remains unclear.All ACS patients aged 75 years and older treated with Percutaneous Coronary Intervention (PCI) from PRAISE dataset were included. The safety and efficacy of Ticagrelor vs Clopidogrel was evaluated with inverse probability of treatment weighting (IPTW). Sensitivity analysis was performed for patients older or equal than 85 years old. All-cause mortality was the primary endpoint, while myocardial infarction (MI), Bleeding Academic Research Consortium (BARC) 3-5 bleedings and Major and Net Adverse Clinical and Cardiac Events (MACE and NACE) were the secondary ones.4287 patients were included, 3197 treated with Clopidogrel and 1090 with Ticagrelor. After 16 ± 3 months, Ticagrelor showed neutral effect on NACE and mortality (HR 0.98; 0.63-1.52, p = 0.94 and HR 0.38; 0.14-1.04, p = 0,06), reduced risk of MACE and MI (HR 0.82; 0.23-0.91, p = 0.03 and HR 0.43; 0.14-0.89, p = 0.04) and increased risk of BARC 3-5 bleeding (HR 2.14; 1.19-3.85, p = 0.001). In very elderly patients (≥85 years) Ticagrelor decreased risk of MI and increased risk of bleeding (HR 0.69; 0.22-0.95, p = 0.04 and HR 2.36; 1.02-5.52, p = 0.04, all 95%CI) with neutral effect on NACE and MACE.In elderly ACS patients treated with PCI, Ticagrelor was associated with neutral effect on all-cause mortality, lower risk MACE and MI compared with Clopidogrel. Such benefit was counterbalanced by increased risk of major bleedings. These results were consistent among patients aged 85 years and older.

Published
2021

9. Valve-in-valve transcatheter aortic valve replacement or re-surgical aortic valve replacement in degenerated bioprostheses: a systematic review and meta-analysis of short and mid-term results

Author

Bruno, F, primary, Elia, E, additional, D'Ascenzo, F, additional, Marengo, G, additional, De Filippo, O, additional, Gallone, G, additional, Andreis, A, additional, Fortuni, F, additional, Salizzoni, S, additional, Rinaldi, M, additional, La Torre, M, additional, Conrotto, F, additional, and De Ferrari, G M, additional

Published
2021
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11. Accuracy of the PARIS score and PCI complexity to predict ischemic events in patients treated with very thin stents in unprotected left main or coronary bifurcations

Author

Gallone, G., D'Ascenzo, F., Conrotto, F., Costa, F., Capodanno, D., Muscoli, S., Chieffo, A., Yoichi, I., Pennacchi, M., Quadri, G., Nunez-Gil, I., Bocchino, P. P., Piroli, F., De Filippo, O., Rolfo, C., Wojakowski, W., Trabattoni, D., Huczek, Z., Venuti, G., Montabone, A., Rognoni, A., Parma, R., Figini, F., Mitomo, S., Boccuzzi, G., Mattesini, A., Cerrato, E., Wanha, W., Smolka, G., Cortese, B., Ryan, N., Bo, M., di Mario, C., Varbella, F., Burzotta, F., Sheiban, I., Escaned, J., Helft, G., De Ferrari, G. M., D'Ascenzo F., di Mario C., Burzotta F. (ORCID:0000-0002-6569-9401), Gallone, G., D'Ascenzo, F., Conrotto, F., Costa, F., Capodanno, D., Muscoli, S., Chieffo, A., Yoichi, I., Pennacchi, M., Quadri, G., Nunez-Gil, I., Bocchino, P. P., Piroli, F., De Filippo, O., Rolfo, C., Wojakowski, W., Trabattoni, D., Huczek, Z., Venuti, G., Montabone, A., Rognoni, A., Parma, R., Figini, F., Mitomo, S., Boccuzzi, G., Mattesini, A., Cerrato, E., Wanha, W., Smolka, G., Cortese, B., Ryan, N., Bo, M., di Mario, C., Varbella, F., Burzotta, F., Sheiban, I., Escaned, J., Helft, G., De Ferrari, G. M., D'Ascenzo F., di Mario C., and Burzotta F. (ORCID:0000-0002-6569-9401)

Abstract

Background: The PARIS risk score (PARIS-rs) and percutaneous coronary intervention complexity (PCI-c) predict clinical and procedural residual ischemic risk following PCI. Their accuracy in patients undergoing unprotected left main (ULM) or bifurcation PCI has not been assessed. Methods: The predictive performances of the PARIS-rs (categorized as low, intermediate, and high) and PCI-c (according to guideline-endorsed criteria) were evaluated in 3,002 patients undergoing ULM/bifurcation PCI with very thin strut stents. Results: After 16 (12–22) months, increasing PARIS-rs (8.8% vs. 14.1% vs. 27.4%, p <.001) and PCI-c (15.2% vs. 11%, p =.025) were associated with higher rates of major adverse cardiac events ([MACE], a composite of death, myocardial infarction [MI], and target vessel revascularization), driven by MI/death for PARIS-rs and target lesion revascularization/stent thrombosis for PCI-c (area under the curves for MACE: PARIS-rs 0.60 vs. PCI-c 0.52, p-for-difference <.001). PCI-c accuracy for MACE was higher in low-clinical-risk patients; while PARIS-rs was more accurate in low-procedural-risk patients. ≥12-month dual antiplatelet therapy (DAPT) was associated with a lower MACE rate in high PARIS-rs patients, (adjusted-hazard ratio 0.42 [95% CI: 0.22–0.83], p =.012), with no benefit in low to intermediate PARIS-rs patients. No incremental benefit with longer DAPT was observed in complex PCI. Conclusions: In the setting of ULM/bifurcation PCI, the residual ischemic risk is better predicted by a clinical risk estimator than by PCI complexity, which rather appears to reflect stent/procedure-related events. Careful procedural risk estimation is warranted in patients at low clinical risk, where PCI complexity may substantially contribute to the overall residual ischemic risk.

Published
2020

12. Impact of Kissing Balloon in Patients Treated with Ultrathin Stents for Left Main Lesions and Bifurcations: An Analysis from the RAIN-CARDIOGROUP VII Study

Author

Gaido, L., D'Ascenzo, Francesca, Imori, Y., Wojakowski, W., Saglietto, A., Figini, F., Mattesini, A., Trabattoni, D., Rognoni, A., Tomassini, F., Bernardi, A., Ryan, N., Muscoli, S., Helft, G., De Filippo, O., Parma, R., De Luca, L., Ugo, F., Cerrato, E., Montefusco, A., Pennacchi, M., Wanha, W., Smolka, G., De Lio, G., Bruno, F., Huczek, Z., Boccuzzi, G., Cortese, B., Capodanno, D., Omede, P., Mancone, M., Nunez-Gil, I., Romeo, Fabio, Varbella, F., Rinaldi, M., Escaned, J., Conrotto, F., Burzotta, Francesco, Chieffo, A., Perl, L., D'Amico, M., Di Mario, Clara, Sheiban, I., Gagnor, A., Giammaria, M., De Ferrari, G. M., D'ascenzo F., Romeo F., Burzotta F. (ORCID:0000-0002-6569-9401), Di Mario C., Gaido, L., D'Ascenzo, Francesca, Imori, Y., Wojakowski, W., Saglietto, A., Figini, F., Mattesini, A., Trabattoni, D., Rognoni, A., Tomassini, F., Bernardi, A., Ryan, N., Muscoli, S., Helft, G., De Filippo, O., Parma, R., De Luca, L., Ugo, F., Cerrato, E., Montefusco, A., Pennacchi, M., Wanha, W., Smolka, G., De Lio, G., Bruno, F., Huczek, Z., Boccuzzi, G., Cortese, B., Capodanno, D., Omede, P., Mancone, M., Nunez-Gil, I., Romeo, Fabio, Varbella, F., Rinaldi, M., Escaned, J., Conrotto, F., Burzotta, Francesco, Chieffo, A., Perl, L., D'Amico, M., Di Mario, Clara, Sheiban, I., Gagnor, A., Giammaria, M., De Ferrari, G. M., D'ascenzo F., Romeo F., Burzotta F. (ORCID:0000-0002-6569-9401), and Di Mario C.

Abstract

Background: There are limited data regarding the impact of final kissing balloon (FKI) in patients treated with percutaneous coronary intervention using ultrathin stents in left main or bifurcations. Methods: All patients undergoing left main or bifurcations percutaneous coronary intervention enrolled in the RAIN registry (Very Thin Stents for Patients With MAIN or BiF in Real Life: The RAIN, a Multicenter Study) evaluating ultrathin stents were included. Major adverse cardiac event (a composite of all-cause death, myocardial infarction, target lesion revascularization, and stent thrombosis) was the primary end point, while its components, along with target vessel revascularization, were the secondary end points. The main analysis was performed comparing patients with and without FKI after adjustment with inverse probability of treatment weighting. Subgroup analyses were performed according to FKI (short [<3 mm] versus long overlap), strategy (provisional versus 2-stent), routine versus bail-out FKI, and the use of imaging and proximal optimization technique. Results: Two thousand seven hundred forty-two patients were included. At 16 months (8-20) follow-up, inverse probability of treatment weighting adjusted rates of major adverse cardiac event were similar between FKI and no-FKI group (15.1% versus 15.5%; P=0.967), this result did not change with use of imaging, proximal optimization technique, or routine versus bail-out FKI. In the 2-stent subgroup, FKI was associated with lower rates of target vessel revascularization (7.8% versus 15.9%; P=0.030) and target lesion revascularization (7.3% versus 15.2%; P=0.032). Short overlap FKI was associated with a lower rate of target lesion revascularization compared with no FKI (2.6% versus 5.4%; P=0.034), while long overlap was not (6.8% versus 5.4%; P=0.567). Conclusions: In patients with bifurcations or unprotected left main treated with ultrathin stents, short overlap FKI is associated with less restenosis. In a 2-st

Published
2020

14. Fractional flow reserve (FFR) guided vs angiography guided coronary artery bypass graft (CABG): a systematic review and meta-analysis

Author

Bruno, F, primary, D'Ascenzo, F, additional, Marengo, G, additional, Manfredi, R, additional, Conrotto, F, additional, Gallone, G, additional, Omede, P, additional, Montefusco, A, additional, Pennone, M, additional, Salizzoni, S, additional, Rinaldi, M, additional, Giustetto, C, additional, and De Ferrari, G, additional

Published
2020
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15. Incidence, predictors and outcomes of Valve-in-valve (ViV) Transcatheter aortic valve replacement (TAVR): a systematic review and meta-analysis

Author

Bruno, F, primary, D'Ascenzo, F, additional, Giordana, F, additional, Saglietto, A, additional, Conrotto, F, additional, De Filippo, O, additional, Grosso Marra, W, additional, Salizzoni, S, additional, Trompeo, A, additional, La Torre, M, additional, D'Amico, M, additional, Rinaldi, M, additional, Giustetto, C, additional, and De Ferrari, G, additional

Published
2020
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16. Predictors of fractional flow reserve/instantaneous wave-free ratio discordance documented during functional coronary stenosis assessment: impact of tailored diagnostic cut-offs on long-term outcomes

Author

De Filippo, O, primary, Gallone, G, additional, D'Ascenzo, F, additional, Peirone, A, additional, Castelli, C, additional, Leone, A.M, additional, Mancone, M, additional, Cerrato, E, additional, Niccoli, G, additional, Rognoni, A, additional, Varbella, F, additional, Omede, P, additional, Conrotto, F, additional, Escaned, J, additional, and De Ferrari, G.M, additional

Published
2020
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20. P2552Triple vs. double antithrombotic therapy in patients needing oral anticoagulation undergoing percutaneous coronary intervention: a meta-analysis

Author

Errigo, D, primary, Saglietto, A, additional, Angelini, F, additional, Lip, G Y H, additional, Lopes, R D, additional, Conrotto, F, additional, Omede, P G, additional, Montefusco, A, additional, Manzano-Fernandez, S, additional, Raposeiras-Rubin, S, additional, Varbella, F, additional, D'Amico, M, additional, D'Ascenzo, F, additional, Rinaldi, M, additional, and Giustetto, C, additional

Published
2019
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21. P1789Outcomes of different approaches for severe aortic stenosis: “"The Deferred-TAVI”, a multicentre study investigating medical and percutaneous therapy in the era of TAVI

Author

Bruno, F, primary, Errica, N, additional, D'Ascenzo, F, additional, Conrotto, F, additional, De Filippo, O, additional, Salizzoni, S, additional, La Torre, M, additional, D'Amico, M, additional, Omede, P, additional, Tarantini, G, additional, Dowling, C, additional, Shamsi, A, additional, and Rinaldi, M, additional

Published
2019
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22. P2731Complete or culprit only revascularization in patients with multivessel disease presenting with cardiogenic shock: a meta-analysis of RCT and adjusted observational results

Author

Bertaina, M B, primary, Ferraro, I F, additional, Omede', P O, additional, Conrotto, F C, additional, Cavender, M C, additional, Claessen, B E C, additional, Henriques, J P S H, additional, Frea, S F, additional, Usmiani, T U, additional, Pennone, M P, additional, Moretti, C M, additional, D'Amico, M D A, additional, and D'Ascenzo, F D A, additional

Published
2018
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23. 6129Prasugrel vs Ticagrelor in patients with acute coronary syndrome and diabetes: a propensity match substudy of RENAMI

Author

Bertaina, M B, primary, Conrotto, F C, additional, Rapoiseras-Roubin, S R, additional, Kinnaird, T K, additional, Ariza-Sole', A A S, additional, Manzano-Fernandez, S M F, additional, Templin, C T, additional, Velicki, L V, additional, Xanthopoulou, I X, additional, Cerrato, E C, additional, Rognoni, A R, additional, Boccuzzi, G B, additional, Durante, A D, additional, Quadri, G Q, additional, and D'Ascenzo, F D A, additional

Published
2018
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25. P5346Long-term clinical outcomes after percutaneous coronary intervention for ostial/midshaft versus distal bifurcations left main coronary artery disease in the second generation drug eluting stents era

Author

Pavani, M, primary, Conrotto, F, additional, D'Ascenzo, F, additional, Tomassini, F, additional, Nunez-Jil, I J, additional, Scacciatella, P, additional, Varbella, F, additional, Colombo, A, additional, Chieffo, A, additional, and Escaned, J, additional

Published
2018
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26. Simplified hybrid algorithms for pressure wire interrogation exploiting advantages of a baseline and contrast Pd/Pa ratio indexes to predict stenosis significance: Insight from the SPARE multicenter prospective study

Author

Cerrato, E., primary, Tomassini, F., additional, Salinas, P., additional, Pavani, M., additional, Conrotto, F., additional, Echavarria-Pinto, M., additional, Macaya, F., additional, Quadri, G., additional, D'Ascenzo, F., additional, Quirós, Alicia, additional, Varbella, F., additional, and Escaned, J., additional

Published
2018
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27. P6106Safety and efficacy of drug eluting stents in patients with spontaneous coronary artery dissection

Author

Conrotto, F., primary, D'Ascenzo, F., additional, Cerrato, E., additional, Macaya, F., additional, Tamburino, C., additional, Van Lavieren, M., additional, Latib, A., additional, Barbanti, M., additional, Pavani, M., additional, Biagioni, C., additional, Macaya, C., additional, Presbitero, P., additional, Varbella, F., additional, Gaita, F., additional, and Escaned, J., additional

Published
2017
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28. P4657Clinical implications of concomitant atherosclerosis in patients with spontaneous coronary artery dissection. Insights from an international multicentric registry

Author

Cerrato, E., primary, Macaya Ten, F., additional, Conrotto, F., additional, Tamburino, C., additional, Van Lavieren, M., additional, Dascenso, F., additional, Latib, A., additional, Barbanti, M., additional, Piek, J., additional, Marzullo, R., additional, Applegate, R., additional, Macaya, C., additional, Gaita, F., additional, Varbella, F., additional, and Escaned, J., additional

Published
2017
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29. 3120Long-term outcomes of different two-stenting bifurcation techniques for unprotected left main coronary bifurcation disease: a FAILS-2 substudy

Author

Pavani, M., primary, Conrotto, F., additional, D'Ascenzo, F., additional, Kawamoto, H., additional, Cerrato, E., additional, Scacciatella, P., additional, Rolfo, C., additional, Garbo, R., additional, Velazquez, R., additional, Varbella, F., additional, D'Amico, M., additional, Chieffo, A., additional, Gaita, F., additional, Colombo, A., additional, and Escaned, J., additional

Published
2017
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30. P2071Single- vs two- stenting technique with second generation drug eluting stent for unprotected left main coronary bifurcation disease: insights from FAILS-2 study

Author

Pavani, M., primary, Conrotto, F., additional, Chieffo, A., additional, Kawamoto, H., additional, D'Ascenzo, F., additional, Cerrato, E., additional, Nunez-Gil, I., additional, Pennone, M., additional, Tomassini, F., additional, Garbo, R., additional, Varbella, F., additional, Moretti, C., additional, Colombo, A., additional, Gaita, F., additional, and Escaned, J., additional

Published
2017
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32. Impact of access on TAVI procedural and midterm follow-up: A meta-analysis of 13 studies and 10,468 patients

Author

Conrotto, F, D'Ascenzo, Fabrizio, Giordana, Francesca, Colaci, C, Sacciatella, P, Biondi Zoccai, G, Moretti, C, D'Amico, M, Gaita, Fiorenzo, and Marra, S.

Subjects
Stroke, Transcatheter Aortic Valve Replacement, Aortic Valve Stenosis, Hemorrhage, Humans, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine
Abstract

Transcatheter aortic valve implantation (TAVI) may be performed using the transfemoral (TF) or transapical (TA) approach in most patients with aortic stenosis. The impact of access choice on peri-procedural and midterm results remains to be defined.Medline and Cochrane Library were searched for articles describing differences in baseline, peri-procedural, and midterm outcomes among patients undergoing TF or TA TAVI. The primary end-point was all-cause mortality after at least 1-year follow-up, while secondary end-points were 30 days mortality and in-hospital complications (bleeding and cerebrovascular events). The independent impact of access choice was evaluated with pooled analysis using a random-effect model.Thirteen studies with 10,468 patients were included. TF was the most exploited strategy (69.5% vs. 30.5%). After adjusting for confounding variables, 30-day and midterm follow-up mortality (median 365 days, range 222-400) were lower in TF patients with a pooled adjusted odds ratio of 0.81 (0.68-0.97 I(2) 99%) and 0.85 (0.80-0.90 I(2) 96%), respectively. Regarding periprocedural outcomes, TF reduced risk of bleedings and strokes (OR of 0.74 [0.66-0.82 I(2) 95%] and 0.91 [0.83-0.99] I(2) 86%, respectively).The TF approach reduces mortality in TAVI patients, due to lower rates of periprocedural bleedings and strokes.

Published
2014

35. Mid-term prognostic value of coronary artery disease in patients undergoing transcatheter aortic valve implantation: A meta-analysis of adjusted

Author

D'Ascenzo, F, Conrotto, F, Giordana, Francesca, Moretti, C, D'Amico, M, Salizzoni, Stefano, Omedè, P, La Torre, M, Thomas, M, Khawaja, Z, Hildick Smith, D, Ussia, G, Barbanti, M, Tamburino, C, Webb, J, Schnabel, Rb, Seiffert, M, Wilde, S, Treede, H, Gasparetto, V, Napodano, M, Tarantini, G, Presbitero, P, Mennuni, M, Rossi, Ml, Gasparini, M, Biondi Zoccai, G, Lupo, M, Rinaldi, Mauro, Gaita, Fiorenzo, and Marra, S.

Published
2013

38. Abstracts

Author

Barthelemy, O., primary, Silvain, J., additional, Brieger, D., additional, Bellemain-Appaix, A., additional, Cayla, G., additional, Beygui, F., additional, Lancar, R., additional, Collet, J. P., additional, Mercadier, A., additional, Montalescot, G., additional, Cha, K. S., additional, Nam, Y. H., additional, Kim, J. H., additional, Park, S. Y., additional, Park, T. H., additional, Kim, M. H., additional, Kim, Y. D., additional, Lee, H. C., additional, Ahn, M. S., additional, Hong, T. J., additional, Blanco, R., additional, Blanco, F., additional, Szarfer, J., additional, Garcia Escudero, A., additional, Gigena, G., additional, Gagliardi, J., additional, Rodriguez, A., additional, Sarmiento, R., additional, Affatatto, S., additional, Riccitelli, M., additional, Petris, A., additional, Datcu, M. D., additional, Pop, C., additional, Radoi, M., additional, Arsenescu-Georgescu, C., additional, Petrescu, I., additional, Petrescu, L., additional, Serban, L., additional, Nechita, E., additional, Tatu-Chitoiu, G., additional, Dorobantu, M., additional, Benedek, I., additional, Craiu, E., additional, Sinescu, C., additional, Ionescu, D. D., additional, Ginghina, C., additional, Minescu, B., additional, Izzo, A., additional, Mantovani, P., additional, Tomasi, L., additional, Dall'oglio, L., additional, Bonatti, S., additional, Rosiello, R., additional, Romano, M., additional, Agostini, F., additional, Zanini, R., additional, Zhao, Z. Y., additional, Wu, Y. J., additional, Li, J. J., additional, Yany, Y. J., additional, Qian, H. Y., additional, Tang, Y. D., additional, Timoteo, A. T., additional, Toste, A., additional, Lousinha, A., additional, Ramos, R., additional, Oliveira, J. A., additional, Ferreira, M. L., additional, Ferreira, R. C., additional, Cabades, C., additional, Diez Gil, J. L., additional, Aguar, P., additional, Sanmiguel, D., additional, Lopez-March, A., additional, Marmol, R., additional, Guerra, L., additional, Girbes, V., additional, Ferrando, J., additional, Rincon De Arellano, A., additional, Patricio, L., additional, Blondal, M., additional, Ainla, T., additional, Marandi, T., additional, Eha, J., additional, Oliveira, M. M., additional, Silva, M. N., additional, Cunha, P. S., additional, Feliciano, J., additional, Silva, S., additional, Kanovsky, J., additional, Kala, P., additional, Parenica, J., additional, Poloczek, M., additional, Prymusova, K., additional, Kubkova, L., additional, Spinar, J., additional, Olinic, D., additional, Homorodean, C., additional, Ober, M., additional, Olinic, M., additional, Andrioaia, C., additional, Condac, A., additional, Masmoudi, M., additional, Berdaoui, B., additional, Labidi, S., additional, Tapia Ballesteros, C., additional, Hernandez Luis, C., additional, Sandin, M. G., additional, Vegas, J. M., additional, Andion, R., additional, Martinez, N., additional, Gonzalez, I. A., additional, Alvarado, M., additional, Amat, I. J., additional, San Roman, J. A., additional, Garcia Gonzalez, M. J., additional, Arroyo Ucar, E., additional, Hernandez Garcia, C., additional, Dorta Martin, M., additional, Marrero Rodriguez, F., additional, Dragu, R., additional, Kapeliovich, M., additional, Hammerman, H., additional, Silva, D., additional, Cortez-Dias, N., additional, Jorge, C., additional, Silva Marques, J., additional, Carilho Ferreira, P., additional, Robalo Martins, S., additional, Almeida Ribeiro, M., additional, Calisto, C., additional, Fiuza, M., additional, Lopes, M. G., additional, Milicevic, P., additional, Panic, M., additional, Stankovic, I., additional, Milicevic, D., additional, Kalezic, T., additional, Kafedzic, S., additional, Ilic, I., additional, Cerovic, M., additional, Putnikovic, B., additional, Neskovic, A., additional, Rott, D., additional, Leibowitz, D., additional, Monhart, Z., additional, Reissigova, J., additional, Grunfeldova, H., additional, Jansky, P., additional, Valente, B., additional, Villanueva Benito, I., additional, Solla, I., additional, Paredes, E., additional, Diaz Castro, O., additional, Calvo, F., additional, Baz, J. A., additional, Iniguez, A., additional, Aleksova, A., additional, Gerloni, R., additional, Belfiore, R., additional, Carriere, C., additional, Barbati, G., additional, Fabris, E., additional, Possa, F., additional, Nait, D., additional, Milo, M., additional, Sinagra, G., additional, Marques, N., additional, Mimoso, J., additional, Gomes, V., additional, Agra Bermejo, R. M., additional, Emad Abu Assi, E. A. A., additional, Sergio Raposeiras Roubin, S. R. R., additional, Pilar Cabanas Grandio, P. C. G., additional, Carlos Pena Gil, C. P. G., additional, Jose Maria Garcia Acuna, J. M. G. A., additional, Jose Ramon Gonzalez Juanatey, J. R. G. J., additional, Daly, M. J., additional, Scott, P., additional, Owens, C. G., additional, Tomlin, A., additional, Smith, B., additional, Adgey, A. A. J., additional, Alvarez-Contreras, L. R., additional, Juarez, U., additional, Altamirano, A., additional, Arias, A., additional, Alvarez-San Gabriel, A., additional, Gonzalez-Pacheco, H., additional, Martinez-Sanchez, C., additional, Rahnavardi, M., additional, Keshtkar-Jahromi, M., additional, Vakili, H., additional, Gholamin, S., additional, Razavi, S. M., additional, Gilis-Januszewski, T., additional, Mellwig, K.- P., additional, Wiemer, M., additional, Gilis-Januszewski, J., additional, Peterschroeder, A., additional, Koerfer, J., additional, Horstkotte, D., additional, Vrsalovic, M., additional, Getaldic, B., additional, Vrkic, N., additional, Pintaric, H., additional, Khan, S., additional, Wasan, B., additional, Moretti, L., additional, Grossi, P., additional, Silenzi, S., additional, Testa, M., additional, Candelori, L., additional, Clementi, L. N., additional, Forlini, M., additional, Lando, L., additional, Pezzuoli, M. L., additional, Corradetti, P., additional, Leurent, G., additional, Pennec, P. Y., additional, Filippi, E., additional, Moquet, B., additional, Hacot, J. P., additional, Druelles, P., additional, Rialan, A., additional, Rouault, G., additional, Coudert, I., additional, Le Breton, H., additional, Gevaert, S., additional, Tromp, F., additional, Vandecasteele, E., additional, De Somer, F., additional, Van Belleghem, Y., additional, Bouchez, S., additional, Martens, F., additional, Herck, I., additional, De Pauw, M., additional, Ludka, O., additional, Sepsi, M., additional, Miklik, R., additional, Dusek, L., additional, Tomcikova, D., additional, Garcia-Acuna, J. M., additional, Aguiar-Souto, P., additional, Raposeiras Roubin, S., additional, Agra-Bermejo, R., additional, Jacquet, M., additional, Abu-Assi, E., additional, Gonzalez-Juanatey, J. R., additional, Ibatov, A., additional, Labrova, R., additional, Karlik, R., additional, Lokaj, P., additional, She, Q., additional, Deng, S. B., additional, Huang, S. H., additional, Gu, L. J., additional, Rong, J. I. A. N., additional, Wu, Z. K., additional, Li, Y., additional, Zhang, J., additional, Parascan, L., additional, Campanile, A., additional, Spinelli, L., additional, Santulli, G., additional, Ciccarelli, M., additional, De Gennaro, S., additional, Assante Di Panzillo, E., additional, Trimarco, B., additional, Iaccarino, G., additional, Bobescu, E., additional, Datcu, G., additional, Dobreanu, D., additional, Doka, B., additional, Charniot, J.- C., additional, Cosson, C., additional, Albertini, J. P., additional, Bittar, R., additional, Giral, P., additional, Cherfils, C., additional, Guillerm, E., additional, Bonnefont-Rousselot, D., additional, Rusali, A., additional, Cojocaru, L., additional, Parepa, I., additional, Koizumi, T., additional, Iida, S., additional, Sato, J., additional, Kikutani, T., additional, Muramatsu, T., additional, Nishimura, S., additional, Komiyama, N., additional, Lee, W. P., additional, Ong, B. B., additional, Haralambos, K., additional, Townsend, D., additional, Rees, J. A. E., additional, Williams, E. J., additional, Halcox, J. P., additional, Mcdowell, I., additional, Damjanovic, M., additional, Koracevic, G., additional, Djordjevic-Radojkovic, D., additional, Pavlovic, M., additional, Krstic, N., additional, Ciric-Zdravkovic, S., additional, Stojkovic, A., additional, Perisic, Z., additional, Apostolovic, S., additional, Faustino, A., additional, Seca, L., additional, Barra, S., additional, Caetano, F., additional, Providencia, R., additional, Silva, J., additional, Gomes, P., additional, Costa, G., additional, Costa, M., additional, Leitao-Marques, A., additional, Volkova, A. L., additional, Arutyunov, G. P., additional, Bylova, N. A., additional, Dayter, I. I., additional, Jao, Y. T. F. N., additional, Fang, C. C., additional, Chen, Y., additional, Yu, C. L., additional, Wang, S. P., additional, Valencia, J., additional, Perez-Berbel, P., additional, Ruiz-Nodar, J. M., additional, Pineda, J., additional, Bordes, P., additional, Quintanilla, M., additional, Mainar, V., additional, Sogorb, F., additional, Santos, N., additional, Serrao, M., additional, Cafe, H., additional, Silva, B., additional, Oliveira, R., additional, Caires, G., additional, Drumond, A., additional, Araujo, J., additional, Providencia, R. A., additional, Gomes, P. L., additional, Pais, J. R., additional, Mota, P., additional, Leitao-Marques, A. M., additional, Farhan, S., additional, Jarai, R., additional, Tentzeris, I., additional, Vogel, B., additional, Freynhofer, M. K., additional, Wojta, J., additional, Huber, K., additional, Poli, M., additional, Trambaiolo, P., additional, Corsi, F., additional, De Luca, M., additional, Mustilli, M., additional, Lukic, V., additional, Simonetti, M., additional, Ferraiuolo, G., additional, Lettino, M., additional, Casella, G., additional, Conte, M. R., additional, De Luca, L., additional, Geraci, G., additional, Ceravolo, R., additional, Pani, A., additional, Fradella, G., additional, Schratter, A., additional, Thiele, H., additional, Klemm, T., additional, Demmin, K., additional, Lehmann, D., additional, Mende, M., additional, Schuler, G., additional, Pittl, U., additional, Chernova, A., additional, Nikulina, S. U., additional, Naruke, T., additional, Inomata, T., additional, Yanagisawa, T., additional, Maekawa, E., additional, Mizutani, T., additional, Shinagawa, H., additional, Nishii, M., additional, Takeuchi, I., additional, Takehana, H., additional, Izumi, T., additional, Paulo, C., additional, Mascarenhas, J., additional, Patacho, M., additional, Pimenta, J., additional, Bettencourt, P., additional, Nardai, S., additional, Szabo, G. Y., additional, Berta, B., additional, Edes, I., additional, Merkely, B., additional, Delgado Silva, J., additional, Baptista, R., additional, Faria, R., additional, Trigo, J., additional, Gago, P., additional, Gheorghe, G., additional, Nanea, I. T., additional, Cristea, A., additional, Almarichi, S., additional, Martins, H., additional, Saraiva, F., additional, Jorge, E., additional, Mendes, P. L., additional, Monteiro, P., additional, Costa, S., additional, Franco, F., additional, Providencia, L. A., additional, Nanea, T., additional, Gheorghe, G. S., additional, Visan, S., additional, Paun, N., additional, Gaber, R., additional, Delewi, R., additional, Nijveldt, R., additional, De Bruin, H. A., additional, Hirsch, A., additional, Van Der Laan, A., additional, Bouma, B. J., additional, Tijssen, J. P. G., additional, Van Rossum, A. C., additional, Zijlstra, F., additional, Piek, J. J., additional, Rus, H., additional, Donea, M., additional, Ciurea, C., additional, Ifteni, G., additional, Casolo, G., additional, Chioccioli, M., additional, Magnacca, M., additional, Del Meglio, J., additional, Comella, A., additional, Baratto, M., additional, Lera, J., additional, Salvadori, L., additional, Tessa, C., additional, Vignali, C., additional, Keca, Z., additional, Momcilov Popin, T., additional, Panic, G., additional, White, R., additional, Mateen, F., additional, Weaver, A., additional, Agmon, Y., additional, Okisheva, E., additional, Tsaregorodtsev, D., additional, Sulimov, V., additional, Amat Santos, I. J., additional, Hernandez, C., additional, Tapia, C., additional, Campo, A., additional, Fredman, D., additional, Svensson, L., additional, Rosenqvist, M., additional, Tadel-Kocjancic, S., additional, Radsel, P., additional, Knafelj, R., additional, Gorjup, V., additional, Noc, M., additional, Zima, E., additional, Jenei, Z. S., additional, Kovacs, E., additional, Osztheimer, I., additional, Molnar, L., additional, Horvath, A., additional, Becker, D., additional, Geller, L., additional, Maggi, R., additional, Furukawa, T., additional, Viscardi, V., additional, Brignole, M., additional, Leal, S. R. N., additional, Dores, H., additional, Rosario, I., additional, Monge, J., additional, Carvalho, M. J., additional, Arroja, I., additional, Leitao, A., additional, Fonseca, C., additional, Aleixo, A., additional, Silva, A., additional, Keuleers, S., additional, Herijgers, P., additional, Herregods, M. C., additional, Budts, W., additional, Dubois, C., additional, Meuris, B., additional, Verhamme, P., additional, Flameng, W., additional, Van De Werf, F., additional, Adriaenssens, T., additional, Badran, H., additional, Elnoamany, M., additional, Lolah, T., additional, Olariu, C., additional, Macarie, C., additional, Mollik, M. A. H., additional, Hassan, A. I., additional, Paul, T. K., additional, Haque, M. Z., additional, Jahan, R., additional, Rahmatullah, M., additional, Khatun, M. A., additional, Rahman, M. T., additional, Chowdhury, M. H., additional, Bustamante Munguira, J., additional, Tamayo, E., additional, Garcia-Cuenca, I., additional, Bustamante, E., additional, Gualis, J., additional, Gomez-Martinez, M. L., additional, Florez, S., additional, Gomez-Herreras, J. I., additional, Ramirez Rodriguez, R., additional, Ramirez Rodriguez, A. M., additional, Garcia-Bello, M. A., additional, Hernadez Ortega, E., additional, Caballero Dorta, E., additional, Garcia Quintana, A., additional, Piro Mastraccio, V., additional, Medina Fernandez Aceytuno, A., additional, Assanelli, E., additional, De Metrio, M., additional, Rubino, M., additional, Lauri, G., additional, Cabiati, A., additional, Campodonico, J., additional, Grazi, M., additional, Moltrasio, M., additional, Marana, I., additional, Marenzi, G., additional, Lovlien, M., additional, Schei, B., additional, Picon-Heras, R., additional, Acebal, C., additional, Garcia Rubira, J. C., additional, Vivas Balcones, D., additional, Nunez-Gil, I., additional, Ruiz-Mateos, B., additional, Ibanez, B., additional, Fernandez-Ortiz, A., additional, Vintila, V. D., additional, Enescu, O. A., additional, Stoicescu, C. I., additional, Udroiu, C., additional, Cinteza, M., additional, Tatu - Chitoiu, G., additional, Vinereanu, D., additional, Fresco, C., additional, De Biasio, M., additional, Muser, D., additional, Sappa, R., additional, Morocutti, G., additional, Bernardi, G., additional, Proclemer, A., additional, Fontanella, B., additional, Affatato, A., additional, Ciccarese, C., additional, Sacchini, M., additional, Volpini, M., additional, Bianchetti, F., additional, Verzura, G., additional, Dei Cas, L., additional, Pudil, R., additional, Blaha, V., additional, Vojacek, J., additional, Paraskevaidis, I., additional, Ikonomidis, I., additional, Parissis, J., additional, Papadopoulos, C., additional, Stasinos, V., additional, Bistola, V., additional, Anastasiou-Nana, M., additional, Shochat, M., additional, Shotan, A., additional, Kazatsker, M., additional, Gurovich, V., additional, Asif, A., additional, Noiman, E., additional, Levy, Y., additional, Blondhaim, D., additional, Rabinovich, P., additional, Meisel, S., additional, Petrovic, S., additional, Glasnovic, J., additional, Tomasevic, M., additional, Sakac, D., additional, Obradovic, S., additional, Londono Sanchez, O., additional, Pacreu, S., additional, Torres, L., additional, Mihaylov, G., additional, Shaban, G. M., additional, Trendafilova, E., additional, Krasteva, V., additional, Mudrov, T. S., additional, Didon, J. P., additional, Panageas, V., additional, Vlachos, N., additional, Pernat, A., additional, Radan, I., additional, Mozina, H., additional, Pepi, P., additional, Cionini, F., additional, Baccaglioni, N., additional, Viertel, A., additional, Havers, J., additional, Ballard, G., additional, Groenefeld, G., additional, Branco, L. M., additional, Ferreira, L., additional, Fiarresga, A., additional, Lettieri, L., additional, Reggiani, A., additional, Juarez Prera, R., additional, Blanco Palacios, G., additional, Martin, A.- C., additional, Manzo Silberman, S., additional, Chaib, A., additional, Varenne, O., additional, Allouch, P., additional, Salengro, E., additional, Jegou, A., additional, Margot, O., additional, Spaulding, C., additional, Diego, A., additional, De Miguel, A., additional, Cuellas, C., additional, Fraile, E., additional, Martin, J., additional, Vega, B., additional, Bangueses, R., additional, Fernandez-Vazquez, F., additional, Perez De Prado, A., additional, Leal, S., additional, Correia, M. J., additional, Monge, J. C., additional, Abecasis, J., additional, Garcia-Garcia, C., additional, Subirana, I., additional, Sala, J., additional, Bruguera, J., additional, Valle, V., additional, Sanz, G., additional, Fiol, M., additional, Aros, F., additional, Marrugat, J., additional, Elosua, R., additional, Barra, S. N. C., additional, Leitao Marques, A., additional, Yang, Y. J., additional, Xu, B., additional, Song, G. Y., additional, G, R. L., additional, Aleksic, A., additional, Serpytis, P., additional, Rucinskas, K., additional, Kalinauskas, A., additional, Karvelyte, N., additional, Santos De Sousa, C. I., additional, Ferreira, S., additional, Calaca, J., additional, Lousada, N., additional, Palma Reis, R., additional, Gualandro, D. M., additional, Seguro, L. F. B. C., additional, Braga, F. G. M., additional, Silvestre, O. M., additional, Lage, R. L., additional, Fabri, J., additional, Oliveira, M. T., additional, Urbano Moral, J. A., additional, Torres Llergo, J., additional, Solanilla Rodriguez, R., additional, Sanchez Gonzalez, A., additional, Martinez Martinez, A., additional, Den Uil, C. A., additional, Lagrand, W. K., additional, Van Der Ent, M., additional, Jewbali, L. S. D., additional, Cheng, J. M., additional, Spronk, P. E., additional, Simoons, M. L., additional, Mornos, C., additional, Dragulescu, D., additional, Ionac, A., additional, Guardado, J., additional, Azevedo, O., additional, Fernandes, M., additional, Canario-Almeida, F., additional, Sanfins, V., additional, Pereira, A., additional, Almeida, J., additional, Kaplunova, V. U., additional, Belenkov, Y. N., additional, Privalova, E. V., additional, Fomin, A. A., additional, Suvorov, A. Y., additional, Goodkova, A., additional, Rubakova, M. G., additional, Kuznetsova, I. A., additional, Semernin, E. N., additional, Keshavarzi, F., additional, Kojuri, J., additional, Mikhailov, V. M., additional, Vezhenkova, I. V., additional, Goodkova, A. Y. A., additional, Pavlovic, I., additional, Schwarz, M., additional, Jakl, G., additional, Smetana, P., additional, Perkmann, T., additional, Mayr, A., additional, Mair, J., additional, Klug, G., additional, Schocke, M., additional, Trieb, T., additional, Jaschke, W., additional, Pachinger, O., additional, Metzler, B., additional, Bronze Carvalho, L., additional, Azevedo, J., additional, Andrade, M. L., additional, Relvas, M. J., additional, Coucello, J., additional, Morais, G., additional, Seabra, M., additional, Afamefule, F., additional, Luaces Mendez, M., additional, Teijeiro-Mestre, R., additional, Nunez-Gil, I. J., additional, Leco-Gil, N., additional, Madronal-Cerezo, E., additional, Zannin, I., additional, Ruiz, J., additional, Orynchak, M. A., additional, Vakalyuk, I. I., additional, Vakalyuk, I. P., additional, Berezin, A., additional, Panasenko, T., additional, Cavusoglu, Y., additional, Cavusoglu, A., additional, Unluoglu, I., additional, Tek, M., additional, Demirustu, C., additional, Gorenek, B., additional, Unalacak, M., additional, Birdane, A., additional, Yuksel, F., additional, Ata, N., additional, Halcox, J. P. J., additional, Beyaztas, A., additional, Entok, E., additional, Uslu, I., additional, Schaefer, A., additional, Flierl, U., additional, Seydelmann, N., additional, Bauersachs, J., additional, Calmac, L., additional, Marinescu, S., additional, Tatu Chitoiu, G., additional, Fruntelata, A. G., additional, Hamdi, S., additional, Maazoun, Y., additional, Neji, A., additional, Farhat, O., additional, Majdoub, M., additional, Ben Hamda, K., additional, Maatouk, F., additional, Balanescu, S. M., additional, Nedelciuc, I., additional, Deleanu, D., additional, Ortan, F., additional, Mot, S., additional, Sinnaeve, P. R., additional, Moreels, S., additional, Coosemans, M., additional, Vydt, T., additional, Desmet, W., additional, Tobing, D., additional, Rifnaldi, R., additional, Juzar, D., additional, Firdaus, I., additional, Dharma, S., additional, Irmalita, I., additional, Kalim, H., additional, Bejiqi, R., additional, Retkoceri, R., additional, Bejiqi, H., additional, Kryeziu, L., additional, Kelmendi, M., additional, Borovci, S. H., additional, Victor, S. M., additional, Gnanaraj, A., additional, Deshmukh, R., additional, Mullasari, A. S., additional, Yahalom, M., additional, Kaiyal, R. S., additional, Roguin, N., additional, Bornstein, J., additional, Atar, S., additional, Farah, R., additional, Seca, L. F., additional, Leitao Marques, A. M., additional, Margato, R., additional, Sousa, P., additional, Ribeiro, H., additional, Rocha, L., additional, Correia, A., additional, Moreira, J. I., additional, Carvalho, H. C., additional, Afifi, M., additional, Abed, N., additional, Suarez-Barrientos, A., additional, Vivas, D., additional, Castro-Ferreira, F., additional, Franco, E., additional, Garcia-Rubira, J. C., additional, Fuster, V., additional, Macaya, C., additional, Ibanez Cabeza, B., additional, Salinger, S., additional, Milic, D., additional, Stanojlovic, T., additional, Kostic, T., additional, Khan, M. A., additional, Vrapi, F., additional, Naeem, K., additional, Davar, J., additional, Hristova, K., additional, Pencheva, G., additional, Radeva, R., additional, Milanov, S., additional, Fareed, A., additional, Oraby, M., additional, Nasr, G. M., additional, Maklady, F., additional, Dupouy, P., additional, Sorensen, J. T., additional, Terkelsen, C. J., additional, Lassen, J. F., additional, Trautner, S., additional, Christensen, E. F., additional, Nielsen, T. T., additional, Botker, H. E., additional, Andersen, H. R., additional, Thygesen, K. A., additional, Checco, L., additional, Usmiani, T., additional, Sbarra, P. L., additional, Boffini, M., additional, Saviolo, R., additional, Grasso, C., additional, Conrotto, F., additional, Marchetti, M., additional, Rinaldi, M., additional, Marra, S., additional, Moscoso Costa, F., additional, Ferreira, J., additional, Raposo, L., additional, Aguiar, C., additional, Trabulo, M., additional, Silva, J. A., additional, Marques, V., additional, Swiatkowski, A., additional, Kowalczyk, J., additional, Lenarczyk, R., additional, Chodor, P., additional, Honisz, G., additional, Was, T., additional, Swierad, M., additional, Sredniawa, B., additional, Polonski, L., additional, Kalarus, Z., additional, Postadzhiyan, A. S., additional, Velinov, H., additional, Velchev, V., additional, Hazarbasanov, D., additional, Apostolova, M., additional, Finkov, B., additional, Petrovic, M., additional, Jovelic, A., additional, Canji, T., additional, Srdanovic, I., additional, Popov, T., additional, Golubovic, M., additional, Pavlovic, K., additional, Cemerlic-Adjic, N., additional, Bro-Jeppesen, J., additional, Kjaergaard, J., additional, Wanscher, M. C., additional, Nielsen, S. L., additional, Rasmussen, L. S., additional, Hassager, C., additional, Khan, M., additional, Crolla, E., additional, Morley, H., additional, Akeroyd, L., additional, Beaini, Y., additional, Morley, C., additional, Bekeredjian, R. H., additional, Krumsdorf, U., additional, Rottbauer, W., additional, Katus, H. A., additional, Pleger, S., additional, Botelho, A., additional, Quintal, N., additional, Faria, P., additional, Gomes, S., additional, Roussel, J. 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Published
2010
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41. Incidence, predictors, and impact on prognosis of systolic pulmonary artery pressure and its improvement after transcatheter aortic valve implantation: A multicenter registry

Author

D Ascenzo, F., Conrotto, F., Salizzoni, S., Rossi, M. L., Nijhoff, F., Gasparetto, V., Marco Barbanti, Mennuni, M., Omedè, P., Grosso Marra, W., Quadri, G., Giordana, F., Tamburino, C., Tarantini, G., Presbitero, P., Napodanno, M., Stella, P., Biondi-Zoccai, G., Agostoni, P., D Amico, M., Moretti, C., Rinaldi, M., Marra, S., and Gaita, F.

Subjects
Aged, 80 and over, Male, Hypertension, Pulmonary, Incidence, aortic stenosis, Aortic Valve Stenosis, Pulmonary Artery, Prognosis, Severity of Illness Index, left ventricular hypertrophy, Transcatheter Aortic Valve Replacement, Treatment Outcome, Italy, Echocardiography, Risk Factors, Humans, Female, Pulmonary Wedge Pressure, Registries, Netherlands, Retrospective Studies
Abstract

Elevated values of systolic pulmonary artery pressure (sPAP) represent a common finding in patients with aortic stenosis and severe left ventricular hypertrophy. Prognostic impact of sPAP and its potential improvement after transcatheter aortic valve implantation (TAVI) remains to be determined.This is a multicenter retrospective registry in five European institutions. All consecutive patients undergoing TAVI were enrolled, and divided into two groups according to sPAP evaluated with echocardiography: ≤40 mm Hg and40 mm Hg. All-cause mortality at follow-up of at least 1 year was the primary endpoint, while 30-day mortality, periprocedural complications, myocardial infarction, stroke, and reintervention rates at follow-up were the secondary endpoints. Among 674 patients enrolled, a total of 319 (47%) had sPAP40 mm Hg. This was associated with higher mortality at 30 days (4.5% vs 8.5%; P=.03) and at a median follow-up of 477 days (17% vs 26%; P=.03). Improvement of sPAP was reported in 113 patients (27%), occurring more frequently in absence of moderate or severe mitral regurgitation and of right ventricle dysfunction. With multivariate adjustment, reduced renal function, insulin-dependent diabetes mellitus, and sPAP40 mm Hg were independent predictors of all-cause mortality, improvement in sPAP values was related to a better survival, while ejection fraction was not.Elevated values of sPAP represent a common finding in patients undergoing TAVI. This parameter, along with its improvement, may be used to stratify risk and determine prognosis for patients undergoing TAVI.

42. Outcomes of Patients Undergoing Balloon Aortic Valvuloplasty in the TAVI Era: A Multicenter Registry

Author

Moretti, C., Chandran, S., Vervueren, P. -L, D Ascenzo, F., Marco Barbanti, Weerackody, R., Boccuzzi, G., Lee, D. -H, La Torre Hernandez, J., Omedè, P., Nijenhuis, V., Igbineweka, N., Lim, P., Berg, T., Carriè, D., Hildick-Smith, D., Gulino, S., Cannata, S., Gargiulo, G., Tamburino, C., Conrotto, F., Meynet, I., Quadri, G., Marangoni, L., Taha, S., Biondi-Zoccai, G., Salizzoni, S., Marra, S., Gaita, F., Moretti, Claudio, Chandran, Sujay, Vervueren, Paul-Loui, D'Ascenzo, Fabrizio, Barbanti, Marco, Weerackody, Roshan, Boccuzzi, Giacomo, Lee, Dae-Hyun, de la Torre Hernandez, Jose, Omedè, Pierluigi, Nijenhuis, Vincent, Igbineweka, Norri, Lim, Patrick, ten Berg, Null, Carriè, Didier, Hildick-Smith, David, Gulino, Simona, Cannata, Stefano, Gargiulo, Giuseppe, Tamburino, Corrado, Conrotto, Federico, Meynet, Ilaria, Quadri, Giorgio, Marangoni, Ludovica, Taha, Salma, Biondi-Zoccai, Giuseppe, Salizzoni, Stefano, Marra, Sebastiano, and Gaita, Fiorenzo

Subjects
Aged, 80 and over, Balloon Valvuloplasty, Male, Cardiac Catheterization, Time Factors, Time Factor, Risk Factor, Aortic Valve Stenosis, Aortic Valve Stenosi, Follow-Up Studie, Female, Follow-Up Studies, Humans, Retrospective Studies, Risk Factors, Transcatheter Aortic Valve Replacement, Treatment Outcome, Heart Valve Prosthesis, Registries, Heart Valve Prosthesi, Retrospective Studie, 80 and over, Human, Aged
Abstract

Few clinical data about indications and prognoses of patients undergoing balloon aortic valvuloplasty (BAV) in the transcatheter aortic valve implantation (TAVI) era have been reported.Data from all consecutive patients undergoing BAV in seven European centers from 2006 to 2013 were collected. Acute results and long-term outcomes were assessed.A total of 811 patients aged 82 ± 9 years were included; 416 patients (51%) underwent BAV as palliative destination therapy, 320 patients (40%) as bridge to TAVI, and 75 patients (9%) as bridge to surgical aortic valve replacement (SAVR). Patients undergoing BAV as destination therapy had a higher risk profile (logistic EuroSCORE, 20 ± 17 vs 22 ± 14 vs 11 ± 8, respectively; P.001). Post procedure, peak gradient decreased from 87 ± 22 mm Hg to 66 ± 22 mm Hg (P.001) and aortic valve area increased from 0.61 ± 0.2 cm2 to 0.8 ± 0.2 cm2 (P.001). At 30 days, the all-cause death rate (6.5% vs 6.2% vs 7.4%, respectively; P=.56) and the rate of life-threatening and major bleedings (8.0% vs 5.7% vs 6.0%, respectively) did not differ between groups. After a mean follow-up of 318 days (range, 116-500 days), rates of all-cause death were similar (30% vs 34% vs 31%, respectively; P.99), although patients undergoing BAV as bridge to SAVR showed a lower cardiovascular death rate (11% vs 11% vs 3%, respectively; P=.04).In the TAVI era, BAV may represent a reasonable option for patients with severe aortic stenosis and temporary contraindications to definite therapy. Given the mortality rates at 30 days, patients should be carefully selected, while events at follow-up are deeply influenced by the decision of whether or not subsequent interventions are performed.

45. Percutaneous closure of atrial septal defect in adults: Very long-term clinical outcome and effects on aortic and mitral valve function

Author

Scacciatella, P., Marra, S., Pullara, A., Conrotto, F., Marchetti, M., Ferraro, G., Pavani, M., Biasco, L., Dario Bongiovanni, Gaita, F., and Orzan, F.

Subjects
Adult, Male, Cardiac Catheterization, Septal Occluder Device, Aortic Valve Insufficiency, Long Term Adverse Effects, Kaplan-Meier Estimate, atrial septal defect, device, aortic regurgitation, mitral regurgitation, Middle Aged, aortic regurgitation, Heart Septal Defects, Atrial, Postoperative Complications, Italy, Echocardiography, Aortic Valve, Outcome Assessment, Health Care, Humans, Mitral Valve, Female, atrial septal defect, mitral regurgitation, device, Aged, Retrospective Studies
Abstract

To investigate the very long-term clinical outcomes of atrial septal defect (ASD) percutaneous closure in adult patients and to evaluate the 12-month effects of the device on aortic and mitral valve function.Over a 12-year period, a total of 110 consecutive patients underwent percutaneous ASD closure. A yearly clinical follow-up was conducted and any adverse event was recorded. In a 55-patient echocardiographic subgroup, the baseline and 12-month aortic and mitral regurgitation rate was recorded.Mean age was 50.9 ± 17 years and 75% of patients were female. Mean ASD echocardiographic dimension was 17.6 ± 6.2 mm (range, 5-36 mm). Procedural success rate was 97%. After a mean follow-up of 61.8 ± 34.9 months (range, 6-167 months), all-cause death occurred in 2 patients (1.8%) and the composite primary outcome of major adverse cardiovascular event (MACE) occurred in 5 patients (4.5%): 2 non-device related cardiac deaths occurred and 3 surgeries were required. The Kaplan-Meier analysis showed an event-free survival at 140 months of 90%. In the 12-month echocardiographic substudy, no case of significant (moderate or severe) new-onset aortic regurgitation was detected, while 1 case (1.8%) of worsening mild-to-moderate aortic regurgitation was described (P=.90). No case of significant new-onset or worsening mitral regurgitation was noted. No patient needed aortic or mitral surgical repair at very long-term follow-up.Transcatheter ASD closure is a safe procedure with satisfactory very long-term clinical outcomes. The ASD device does not significantly affect aortic and mitral valve function.

46. Catheterization laboratory activity before and during COVID-19 spread: A comparative analysis in Piedmont, Italy, by the Italian Society of Interventional Cardiology (GISE)

Author

Giacomo Boccuzzi, Ferdinando Varbella, Giorgio Baralis, Andrea Gagnor, Angelo Di Leo, Andrea Rognoni, Leonardo De Martino, Enrico Cerrato, Francesco Tomassini, Giuseppe Musumeci, Maurizio Alessandro Reale, Giovanni Esposito, Giorgio Quadri, Fabrizio Ugo, Giuseppe Tarantini, Michele De Benedictis, Pierluigi Soldà, Giuseppe Patti, Alessandra Truffa, Federico Conrotto, Elvis Brscic, Elena Gribaudo, Fabio Ferrari, Giuseppe Pietro Greco Lucchina, Tiziana Montaldo, Quadri, G., Rognoni, A., Cerrato, E., Baralis, G., Boccuzzi, G., Brscic, E., Conrotto, F., De Benedictis, M., De Martino, L., Di Leo, A., Ferrari, F., Gagnor, A., Greco Lucchina, G. P., Montaldo, T., Patti, G., Gribaudo, E., Reale, M. A., Solda, P., Tomassini, F., Truffa, A., Ugo, F., Varbella, F., Esposito, G., Tarantini, G., and Musumeci, G.

Subjects
medicine.medical_specialty, Percutaneous, Coronavirus disease 2019 (COVID-19), Transcatheter aortic, Short Communication, 030204 cardiovascular system & hematology, Mitraclip, TAVR, Coronary Angiography, GISE, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Percutaneous Coronary Intervention, Organizational change, medicine, Humans, 030212 general & internal medicine, Pandemics, COVID-19, PCI, Piedmont, Interventional cardiology, Pandemic, business.industry, MitraClip, Outpatient visits, Italy, Emergency medicine, Conventional PCI, Mitral Valve, business, Cardiology and Cardiovascular Medicine, Human
Abstract

Background COronaVIrus Disease 19 (COVID-19) led to the reorganization of Cardiology Units in terms of working spaces and healthcare personnel. In this scenario, both outpatient visits and elective interventional cardiology procedures were suspended and/or postponed. We aimed to report the impact of COVID-19 on interventional coronary and structural procedures in Piedmont, Italy. Methods The number of coronary angiographies (CAG), percutaneous coronary interventions (PCI), primary PCI (pPCI), transcatheter aortic valve replacements (TAVR) and Mitraclip performed in Piedmont between March 1st and April 20th, 2020 (CoV-time) were collected from each catheterization laboratory and compared to the number of procedures performed the year before in the same months (NoCoV-time). Results Procedural data from 18 catheterization laboratories were collected. Both coronary (5498 versus 2888: difference: −47.5%; mean 305.4 VS 160.4; p = 0.002) and structural (84 versus 17: difference: −79.8%; mean 4.7 Vs 0.9; p, Highlights • COronaVIrus Disease 19 (COVID-19) led to the reorganization of Cardiology Units • Interventional procedures during COVID-19 suffered a dramatic decrease in Piedmont • Structured clinical pathways should be created, together with awareness campaigns.

Published
2021
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49. Endothelial Dysfunction Marker Variation in Young Adults with Chronic Apical Periodontitis before and after Endodontic Treatment

Author

Francesca Silvagno, Milena Maule, Elisabetta Aldieri, Damiano Pasqualini, Loredana Bergandi, Federico Conrotto, Paolo Scacciatella, Beatrice Giuggia, Elio Berutti, Allegra Comba, Mario Alovisi, Nicola Scotti, Bergandi L., Giuggia B., Alovisi M., Comba A., Silvagno F., Maule M., Aldieri E., Scotti N., Scacciatella P., Conrotto F., Berutti E., and Pasqualini D.

Subjects
0301 basic medicine, medicine.medical_specialty, Intercellular Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, endothelial activation, Inflammation, Gastroenterology, endothelial dysfunction, Proinflammatory cytokine, Endothelial activation, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Apical periodontitis, Internal medicine, Periapical Periodontiti, medicine, Humans, Endothelial dysfunction, Periodontitis, Cytokine, Dental Implant, General Dentistry, Dental Implants, business.industry, Interleukin, Biomarker, 030206 dentistry, medicine.disease, Dentistry (all), 030104 developmental biology, Apical periodontiti, Cytokines, Endothelium, Vascular, medicine.symptom, Endothelin receptor, business, Biomarkers, Periapical Periodontitis, Human
Abstract

Introduction Cardiovascular diseases are the leading cause of mortality worldwide. Apical periodontitis (AP) has been associated with an increased risk of cardiovascular diseases. A correlation has been shown between chronic AP and endothelial dysfunction (ED), but there is no evidence to indicate ED improves after endodontic treatment in patients with periapical lesions. The aim of this study was to investigate vascular and molecular markers of early ED before and after root canal treatment in young adults with chronic AP. Methods Twenty control subjects and 21 patients with AP were assessed at baseline. The AP patients were also evaluated 2 and 12 months post-treatment. Endothelial flow reserve was assessed via an endothelial function test, and enzyme-linked immunosorbent assays were used to evaluate plasma levels of proinflammatory cytokines interleukin (IL)-1, IL-6, and tumor necrosis factor alpha; vasoconstrictor ED marker endothelin (ET)-1; circulating endothelial adhesion markers intercellular adhesion molecule 1 (ICAM-1)/CD54 and soluble vascular cellular adhesion molecule (sVCAM)-1/CD106; soluble CD14; and the endothelial leukocyte adhesion molecule (E-selectin). Results AP was associated with increased serum levels of ET-1, ICAM-1, E-selectin, IL-1, and sCD14, suggesting early vascular ED, with no macroscopic evidence of a reduction in endothelial flow reserve. Root canal treatment ameliorated inflammation and early ED, lowering plasma levels of IL-1, sCD14, ET-1, ICAM-1/CD54, and E-selectin to those of control subjects. Conclusions Our findings suggest that AP may drive early vascular ED and that the endodontic therapy of AP ameliorates early ED.

Published
2018

50. Early and mid-term outcomes of 1904 patients undergoing transcatheter balloon-expandable valve implantation in Italy: results from the Italian Transcatheter Balloon-Expandable Valve Implantation Registry (ITER)

Author

Salizzoni, Stefano, D'Onofrio, Augusto, Agrifoglio, Marco, Colombo, Antonio, Chieffo, Alaide, Cioni, Micaela, Besola, Laura, Regesta, Tommaso, Rapetto, Filippo, Tarantini, Giuseppe, Napodano, Massimo, Gabbieri, Davide, Saia, Francesco, Tamburino, Corrado, Ribichini, Flavio, Cugola, Diego, Aiello, Marco, Sanna, Francesco, Iadanza, Alessandro, Pompei, Esmeralda, Stefàno, Pierluigi, Cappai, Antioco, Minati, Alessandro, Cassese, Mauro, Martinelli, Gian Luca, Agostinelli, Andrea, Fiorilli, Rosario, Casilli, Francesco, Reale, Maurizio, Bedogni, Francesco, Petronio, Anna Sonia, Mozzillo, Rosa Alba, Bonmassari, Roberto, Briguori, Carlo, Liso, Armando, Sardella, Gennaro, Bruschi, Giuseppe, Fiorina, Claudia, Filippini, Claudia, Moretti, Claudio, D'Amico, Maurizio, La Torre, Michele, Conrotto, Federico, Di Bartolomeo, Roberto, Gerosa, Gino, Rinaldi, Mauro, Tavi, Team, Pierli, Carlo, Sincropi, Giuseppe, D'Ascenzi, Flavio, Salizzoni, S, D'Onofrio, A, Agrifoglio, M, Colombo, A, Chieffo, A, Cioni, M, Besola, L, Regesta, T, Rapetto, F, Tarantini, G, Napodano, M, Gabbieri, D, Saia, F, Tamburino, C, Ribichini, F, Cugola, D, Aiello, M, Sanna, F, Iadanza, A, Pompei, E, Stefàno, P, Cappai, A, Minati, A, Cassese, M, Martinelli, Gl, Agostinelli, A, Fiorilli, R, Casilli, F, Reale, M, Bedogni, F, Petronio, A, Mozzillo, Ra, Bonmassari, R, Briguori, C, Liso A, Sardella, G, Bruschi, G, Fiorina, C, Filippini, C, Moretti, C, D'Amico, M, La Torre, M, Conrotto, F, Di Bartolomeo, R, Gerosa, G, Rinaldi, M, Tavi, Team, Rubino, A, and Et, Al

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Registry, 030204 cardiovascular system & hematology, Preoperative care, law.invention, Transcatheter Aortic Valve Replacement, TAVI, 03 medical and health sciences, 0302 clinical medicine, law, Internal medicine, medicine, Humans, Registries, 030212 general & internal medicine, Myocardial infarction, Stroke, Aged, Aged, 80 and over, Bioprosthesis, Aortic stenosis, business.industry, Incidence (epidemiology), Aortic Valve Stenosis, Echocardiography, Female, Italy, Treatment Outcome, Heart Valve Prosthesis, Atrial fibrillation, General Medicine, Perioperative, medicine.disease, Surgery, Aortic valve stenosis, Cardiology, Artificial cardiac pacemaker, Cardiology and Cardiovascular Medicine, business
Abstract

Objectives The aim of this multicentre study is to report the clinical experiences of all patients undergoing transcatheter aortic valve implantation (TAVI) with a balloon-expandable device in Italy. Methods The Italian Transcatheter balloon-Expandable valve Registry (ITER) is a real-world registry that includes patients who have undergone TAVI with the Sapien (Edwards Lifesciences, Irvine, CA, USA) bioprosthesis in Italy since it became available in clinical practice. From 2007 to 2012, 1904 patients were enrolled to undergo TAVI in 33 Italian centres. Outcomes were classified according to the updated Valve Academic Research Consortium (VARC-2) definitions. A multivariable analysis was performed to identify independent predictors of all-cause mortality. Results Mean age was 81.7 (SD:6.2) years, and 1147 (60.2%) patients were female. Mean Logistic EuroSCORE was 21.1% (SD:13.7). Transfemoral, transapical, transaortic and transaxillary TAVI was performed in 1252 (65.8%), 630 (33.1%), 18 (0.9%) and 4 (0.2%) patients, respectively. Operative mortality was 7.2% (137 patients). The VARC-2 outcomes were as follows: device success, 88.1%; disabling stroke, 1.0%; life-threatening and major bleeding 9.8 and 10.5%, respectively; major vascular complication, 9.7%; acute kidney injury, 8.2%; acute myocardial infarction ≤72 h, 1.5%. Perioperative pacemaker implantation was necessary in 116 (6.1%) patients. At discharge, the mean transprosthetic gradient was 10.7 (SD:4.5) mmHg. Incidence of postoperative mild, moderate or severe paravalvular leak was, respectively, 32.1, 5.0 and 0.4%. A total of 444/1767 (25.1%) deaths after hospital discharge were reported: of these, 168 (37.8%) were classified as cardiac death. Preoperative independent predictors of all-cause mortality were male gender (HR: 1.395; 95% CI:1.052-1.849); overweight, BMI 25-30 kg/m2 (HR: 0.775; 95% CI: 0.616-0.974); serum creatinine level (every 1 mg/dl increase; HR: 1.314; 95% CI:1.167-1.480); haemoglobin level (every 1 g/dl increase; HR: 0.905; 95% CI:0.833-0.984); critical preoperative state (HR: 2.282; 95% CI: 1.384-3.761); neurological dysfunction (HR: 1.552; 95% CI:1.060-2.272); atrial fibrillation (HR: 1.556; 95% CI:1.213-1.995); pacemaker rhythm (HR: 1.948; 95% CI:1.310-2.896); NYHA Class III or IV (HR: 1.800; 95% CI:1.205-2.689 or HR: 2.331; 95% CI:1.392-3.903, respectively). Conclusions TAVI with a balloon-expandable device in the 'real world' shows good mid-term outcomes in terms of survival, technical success, valve-related adverse events and haemodynamic performance.

Published
2016

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