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Your search keyword '"Cong-Shan, Zhu"' showing total 15 results
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15 results on '"Cong-Shan, Zhu"'

1. Mechanisms of the refractive index change in femtosecond laser-irradiated Au(super 3+) -doped silicate glasses

Author

Quan-Zhong Zhao, Jian-Rong Qiu, Xiong-Wei Jiang, Chong-Hun Zhao, and Cong-Shan Zhu

Subjects
Metallic glasses -- Optical properties, Gold compounds -- Optical properties, Silicates -- Optical properties, Refractive index -- Research, Physics
Abstract

The refractive index change in Au(super+3) -doped silicate glasses irradiated by a femtosecond laser and successive heat treatment is reported. The mechanism of the refractive index and other observed phenomenon are discussed.

Published
2004

2. Charge-conversional and pH-sensitive PEGylated polymeric micelles as efficient nanocarriers for drug delivery

Author

Gong-Yan, Liu, Min, Li, Cong-Shan, Zhu, Qiao, Jin, Zong-Cai, Zhang, and Jian, Ji

Subjects
Drug Carriers, Delayed-Action Preparations, Hydrolysis, Humans, Nanoparticles, Antineoplastic Agents, Hep G2 Cells, Drug Screening Assays, Antitumor, Hydrogen-Ion Concentration, Micelles, Polyethylene Glycols
Abstract

A novel amphiphilic copolymer, poly (ethylene glycol)-graft-polyethyleneimine/amide (PEG-g-PEI/amide), is synthesized by grafting PEG and1,2-cis-Cyclohexanedicarboxylic anhydride onto the PEI. PEGylated polymeric micelles can be assembled from the amphiphilic copolymers with well-defined nano-sizes, and anti-cancer drugs are successfully loaded into micelle core formed by the amide. The amides with neighboring carboxylic acid groups exhibit pH-dependent hydrolysis and can reversibly shield the cationic charge of amine groups on the PEI, giving the micelles a charge-conversion property from negative to positive in acidic tumor tissue environment. Meanwhile, the cleavage of amide bonds at acidic pH also results in the disassembly of the micelle and pH-responsive drug release. These micelles are promising drug delivery systems due to their smart properties: PEGylation, suitable size, charge-conversion, and simultaneous pH-sensitive drug release.

Published
2014

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