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830 results on '"Confalonieri, Marco"'

1. Contributors

Author

Amrein, Karin, primary, Bertsch-Gout, Marcel, additional, Borráz-León, Javier I., additional, Bui, Alexandra, additional, Chapman, Karen, additional, Chaudhuri, Dipayan, additional, Chen, Alon, additional, Chiappelli, Francesco, additional, Chrousos, George P., additional, Confalonieri, Marco, additional, Conway de Macario, Everly, additional, Cornell, Jessica, additional, Dantzer, Robert, additional, Dhabhar, Firdaus S., additional, Dong, Tao, additional, Dyrma, Sherina, additional, Eccles, Melissa, additional, Feldotto, Martin, additional, Gilardi, Josh, additional, Godbout, Jonathan P., additional, Gouin, Jean-Philippe, additional, Groth, David, additional, Hakamata, Yuko, additional, Hori, Hiroaki, additional, James, Eddie A., additional, Khakshooy, Allen, additional, Kuperman, Yael, additional, Lebow, Maya, additional, Lee, Royce, additional, Macario, Alberto J.L., additional, Marshall, Gailen D., additional, Matovic, Sara, additional, Meduri, G. Umberto, additional, Meibohm, Bernd, additional, Milligan Armstrong, Ayeisha, additional, Mitra, Sirsha, additional, Morris, Matthew C., additional, Patil, Chandrashekhar D., additional, Psarra, Anna-Maria G., additional, Rantala, Markus J., additional, Reder, Anthony T., additional, Rochwerg, Bram, additional, Rummel, Christoph, additional, Salinas, Shelbi, additional, Sheridan, John F., additional, Shukla, Deepak, additional, Sirisha, V.L., additional, Suprasanna, Penna, additional, Tang, Ming-Xuan, additional, Verdile, Giuseppe, additional, Volety, Ipsita, additional, Whiteside, Theresa L., additional, Woodfield, Amy, additional, Yin, Wenyuan, additional, Young, Morag, additional, and Zhou, Miou, additional

Published
2024
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2. Right ventricular phenotyping in incident patients with idiopathic pulmonary arterial hypertension

Author

Ghio, Stefano, Badagliacca, Roberto, D’Alto, Michele, Scelsi, Laura, Argiento, Paola, Brunetti, Natale D., Casu, Gavino, Cedrone, Nadia, Confalonieri, Marco, Corda, Marco, Correale, Michele, D’Agostino, Carlo, De Tommasi, Elisabetta, Filomena, Domenico, Galgano, Giuseppe, Greco, Alessandra, Grimaldi, Massimo, Lombardi, Carlo, Madonna, Rosalinda, Manzi, Giovanna, Mercurio, Valentina, Mihai, Alexandra, Mulè, Massimiliano, Paciocco, Giuseppe, Papa, Silvia, Recchioni, Tommaso, Romaniello, Antonella, Romeo, Emanuele, Stolfo, Davide, Vitulo, Patrizio, Benza, Raymond L., and Vizza, Carmine D.

Published
2024
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5. Ventilatory associated barotrauma in COVID-19 patients: A multicenter observational case control study (COVI-MIX-study)

Author

Vetrugno, Luigi, Castaldo, Nadia, Fantin, Alberto, Deana, Cristian, Cortegiani, Andrea, Longhini, Federico, Forfori, Francesco, Cammarota, Gianmaria, Grieco, Domenico Luca, Isola, Miriam, Navalesi, Paolo, Maggiore, Salvatore Maurizio, Bassetti, Matteo, Chetta, Alfredo, Confalonieri, Marco, De Martino, Maria, Ferrari, Giovanni, Francisi, Daniela, Luzzati, Roberto, Meini, Simone, Scozzafava, Mariano, Sozio, Emanuela, Tascini, Carlo, Bassi, Flavio, Patruno, Vincenzo, De Robertis, Edoardo, Aldieri, Chiara, Ball, Lorenzo, Baratella, Elisa, Bartoletti, Michele, Boscolo, Annalisa, Burgazzi, Barbara, Catalanotti, Vito, Confalonieri, Paola, Corcione, Silvia, De Rosa, Francesco Giuseppe, De Simoni, Alessandro, Bono, Valerio Del, Tria, Roberta Di, Forlani, Sara, Giacobbe, Daniele Roberto, Granozzi, Bianca, Labate, Laura, Lococo, Sara, Lupia, Tommaso, Matellon, Carola, Mehrabi, Sara, Morosi, Sabrina, Mongodi, Silvia, Mura, Maddalena, Nava, Stefano, Pol, Riccardo, Pettenuzzo, Tommaso, Quyen, Nguyen Hoang, Rescigno, Carolina, Righi, Elda, Ruaro, Barbara, Salton, Francesco, Scabini, Silvia, Scarda, Angelo, Sibani, Marcella, Tacconelli, Evelina, Tartaglione, Gennaro, Tazza, Beatrice, Vania, Eleonora, Viale, Pierluigi, Vianello, Andrea, Visentin, Alessandro, Zuccon, Umberto, Meroi, Francesco, and Buonsenso, Danilo

Published
2023
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7. GRAd-COV2 vaccine provides potent and durable humoral and cellular immunity to SARS-CoV-2 in randomized placebo-controlled phase 2 trial

Author

Ziviani, Luigi, Malescio, Feliciana, Turrini, Irene, Lawlor, Rita, Romano, Annamaria, Nunziata, Mariagrazia, Armato, Salvatore, Mazzeo, Nicole, Carleo, Maria Aurora, Dell’Isola, Chiara, Pisapia, Raffaella, Pontarelli, Agostina, Olivani, Andrea, Grasselli, Sara, Laccabue, Diletta, Leoni, Maria Cristina, Paolillo, Franco, Mancini, Annalisa, Ruaro, Barbara, Confalonieri, Marco, Salton, Francesco, Mancarella, Giulia, Marocco, Raffaella, De Masi, Margherita, Belvisi, Valeria, Lamonica, Silvia, Cingolani, Antonella, Seguiti, Cristina, Brambilla, Paola, Ferraresi, Alice, Lupi, Matteo, Ludovisi, Serena, Renisi, Giulia, Massafra, Roberta, Pellicciotta, Martina, Armiento, Luciana, Vimercati, Stefania, Piacenza, Mariagrazia, Bonfanti, Paolo, Columpsi, Paola, Cazzaniga, Marina Elena, Rovelli, Cristina, Ceresini, Mariaelena, Previtali, Letizia, Trentini, Laura, Alcantarini, Chiara, Rugge, Walter, Biffi, Stefano, Poletti, Federica, Rostagno, Roberto, Moglia, Roberta, De Negri, Ferdinando, Fini, Elisabetta, Cangialosi, Alice, Bruno, Serena Rita, Rizzo, Marianna, Niglio, Mariangela, Stritto, Anna Dello, Matano, Alfredo, Petruzziello, Arnolfo, Valsecchi, Pietro, Pieri, Teresa, Altamura, Mauro, Calamo, Angela, Giannelli, Anna, Menolascina, Stefania, Di Bari, Silvia, Mauro, Vera, Aronica, Raissa, Segala, Daniela, Cultrera, Rosario, Sighinolfi, Laura, Abbott, Michelle, Gizzi, Andrea, Marascia, Federica Guida, Valenti, Giacomo, Feasi, Marcello, Bobbio, Nicoletta, Del Puente, Filippo, Nicosia, Alfredo, Frascà, Martina, Mazzoleni, Miriam, Garofalo, Nadia, Ammendola, Virginia, Grazioli, Fabiana, Napolitano, Federico, Vitelli, Alessandra, Marcellini, Valentina, Capone, Stefania, Fusco, Francesco M., Milleri, Stefano, Borrè, Silvio, Carbonara, Sergio, Lo Caputo, Sergio, Leone, Sebastiano, Gori, Giovanni, Maggi, Paolo, Cascio, Antonio, Lichtner, Miriam, Cauda, Roberto, Dal Zoppo, Sarah, Cossu, Maria V., Gori, Andrea, Roda, Silvia, Confalonieri, Paola, Bonora, Stefano, Missale, Gabriele, Codeluppi, Mauro, Mezzaroma, Ivano, Capici, Serena, Pontali, Emanuele, Libanore, Marco, Diani, Augusta, Lanini, Simone, Battella, Simone, Contino, Alessandra M., Piano Mortari, Eva, Genova, Francesco, Parente, Gessica, Dragonetti, Rosella, Colloca, Stefano, Visani, Luigi, Iannacone, Claudio, Carsetti, Rita, Folgori, Antonella, and Camerini, Roberto

Published
2023
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11. High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation

Author

Rehman, Michael, Vodret, Simone, Braga, Luca, Guarnaccia, Corrado, Celsi, Fulvio, Rossetti, Giulia, Martinelli, Valentina, Battini, Tiziana, Long, Carlin, Vukusic, Kristina, Kocijan, Tea, Collesi, Chiara, Ring, Nadja, Skoko, Natasa, Giacca, Mauro, Del Sal, Giannino, Confalonieri, Marco, Raspa, Marcello, Marcello, Alessandro, Myers, Michael P, Crovella, Sergio, Carloni, Paolo, and Zacchigna, Serena

Subjects
Lung, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Actins, Animals, Calcium, Cell Differentiation, Cells, Cultured, Disease Models, Animal, Drug Repositioning, Endoplasmic Reticulum Stress, Fibrosis, Haloperidol, Humans, Intravital Microscopy, Mice, Myocardium, Myofibroblasts, Optical Imaging, Primary Cell Culture, RNA Interference, RNA, Small Interfering, Receptor, Notch1, Receptors, sigma, Signal Transduction, Cell Biology, Drug screens, Pulmonology, Signal transduction
Abstract

Fibrosis is a hallmark in the pathogenesis of various diseases, with very limited therapeutic solutions. A key event in the fibrotic process is the expression of contractile proteins, including α-smooth muscle actin (αSMA) by fibroblasts, which become myofibroblasts. Here, we report the results of a high-throughput screening of a library of approved drugs that led to the discovery of haloperidol, a common antipsychotic drug, as a potent inhibitor of myofibroblast activation. We show that haloperidol exerts its antifibrotic effect on primary murine and human fibroblasts by binding to sigma receptor 1, independent from the canonical transforming growth factor-β signaling pathway. Its mechanism of action involves the modulation of intracellular calcium, with moderate induction of endoplasmic reticulum stress response, which in turn abrogates Notch1 signaling and the consequent expression of its targets, including αSMA. Importantly, haloperidol also reduced the fibrotic burden in 3 different animal models of lung, cardiac, and tumor-associated fibrosis, thus supporting the repurposing of this drug for the treatment of fibrotic conditions.

Published
2019

13. Pirfenidone in Idiopathic Pulmonary Fibrosis: Real-World Observation on Efficacy and Safety, Focus on Patients Undergoing Antithrombotic and Anticoagulant.

Author

Reccardini, Nicolò, Chernovsky, Maria, Salton, Francesco, Confalonieri, Paola, Mondini, Lucrezia, Barbieri, Mariangela, Romallo, Antonio, Maggisano, Marta, Torregiani, Chiara, Geri, Pietro, Hughes, Michael, Campochiaro, Corrado, Confalonieri, Marco, Scarda, Angelo, Zuccon, Umberto, and Ruaro, Barbara

Subjects
IDIOPATHIC pulmonary fibrosis, INTERSTITIAL lung diseases, PULMONARY function tests, TERMINATION of treatment, VITAL capacity (Respiration), LUNGS
Abstract

Idiopathic pulmonary fibrosis (IPF) is a rare and progressive interstitial lung disease characterized by irreversible distortion of lung architecture and subsequent loss of pulmonary function. Pirfenidone is an antifibrotic agent associated with increased progression-free survival and overall survival rates, but it carries multiple side effects. The aim of the study was to examine the efficacy and safety profile of pirfenidone in a real-life context, with a focus on the concomitant use of antithrombotic and/or anticoagulant treatments. The clinical and functional data (forced vital capacity [FVC], forced expiratory volume in 1 s [FEV1], diffusing lung capacity for carbon monoxide [DLCO], and 6 min walking test distance [6MWD]) of all IPF patients treated with pirfenidone and referred to our two centers between 2019 and 2022 were retrospectively analyzed at baseline, 6 and 12 months after the start of treatment. A total of 55 IPF subjects undergoing pirfenidone treatment were included in the analysis (45.5% females, median [IQR] age at disease onset 68.0 [10.0] years, median [IQR] age at baseline 69.0 [10.8] years). Compared to baseline, at 12 months, FVC (86.0% vs. 80.0%; p = 0.023) and DLCO (44.0% vs. 40.0%; p = 0.002) were significantly reduced, while FEV1 (p = 0.304) and 6MWD (p = 0.276) remained stable; no significant change was recorded at 6 months. Most of the reported adverse events were mild or moderate. Gastrointestinal intolerance (9.1%) was the main cause of treatment discontinuation. A total of 5% of patients reported at least one minor bleeding event, although all episodes occurred in those receiving concomitant antithrombotic or anticoagulant. Overall, this real-life experience confirms the efficacy and safety profile of pirfenidone in the case of the concomitant use of antithrombotic and/or anticoagulant drugs. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Oscillometry Longitudinal Data on COVID-19 Acute Respiratory Distress Syndrome Treated with Non-Invasive Respiratory Support

Author

Torregiani, Chiara, primary, Baratella, Elisa, additional, Segalotti, Antonio, additional, Ruaro, Barbara, additional, Salton, Francesco, additional, Confalonieri, Paola, additional, Tavano, Stefano, additional, Lapadula, Giulia, additional, Bozzi, Chiara, additional, Confalonieri, Marco, additional, Dellaca’, Raffaele, additional, and Veneroni, Chiara, additional

Published
2024
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18. Nailfold Capillaroscopy Analysis Can Add a New Perspective to Biomarker Research in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Author

Screm, Gianluca, primary, Mondini, Lucrezia, additional, Confalonieri, Paola, additional, Salton, Francesco, additional, Trotta, Liliana, additional, Barbieri, Mariangela, additional, Mari, Marco, additional, Reccardini, Nicolò, additional, Della Porta, Rossana, additional, Kodric, Metka, additional, Bandini, Giulia, additional, Hughes, Michael, additional, Bellan, Mattia, additional, Lerda, Selene, additional, Confalonieri, Marco, additional, and Ruaro, Barbara, additional

Published
2024
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19. Functional Progression after Dose Suspension or Discontinuation of Nintedanib in Idiopathic Pulmonary Fibrosis: A Real-Life Multicentre Study

Author

Ruaro, Barbara, primary, Salotti, Andrea, additional, Reccardini, Nicolò, additional, Kette, Stefano, additional, Da Re, Beatrice, additional, Nicolosi, Salvatore, additional, Zuccon, Umberto, additional, Confalonieri, Marco, additional, Mondini, Lucrezia, additional, Pozzan, Riccardo, additional, Hughes, Michael, additional, Confalonieri, Paola, additional, and Salton, Francesco, additional

Published
2024
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22. Pirfenidone and Nintedanib in Pulmonary Fibrosis: Lights and Shadows.

Author

Chianese, Maria, Screm, Gianluca, Salton, Francesco, Confalonieri, Paola, Trotta, Liliana, Barbieri, Mariangela, Ruggero, Luca, Mari, Marco, Reccardini, Nicolò, Geri, Pietro, Hughes, Michael, Lerda, Selene, Confalonieri, Marco, Mondini, Lucrezia, and Ruaro, Barbara

Subjects
PULMONARY fibrosis, IDIOPATHIC pulmonary fibrosis, INTERSTITIAL lung diseases, VITAL capacity (Respiration), PULMONARY function tests, ELECTROCONVULSIVE therapy
Abstract

Pirfenidone and Nintedanib are specific drugs used against idiopathic pulmonary fibrosis (IPF) that showed efficacy in non-IPF fibrosing interstitial lung diseases (ILD). Both drugs have side effects that affect patients in different ways and have different levels of severity, making treatment even more challenging for patients and clinicians. The present review aims to assess the effectiveness and potential complications of Pirfenidone and Nintedanib treatment regimens across various ILD diseases. A detailed search was performed in relevant articles published between 2018 and 2023 listed in PubMed, UpToDate, Google Scholar, and ResearchGate, supplemented with manual research. The following keywords were searched in the databases in all possible combinations: Nintedanib; Pirfenidone, interstitial lung disease, and idiopathic pulmonary fibrosis. The most widely accepted method for evaluating the progression of ILD is through the decline in forced vital capacity (FVC), as determined by respiratory function tests. Specifically, a decrease in FVC over a 6–12-month period correlates directly with increased mortality rates. Antifibrotic drugs Pirfenidone and Nintedanib have been extensively validated; however, some patients reported several side effects, predominantly gastrointestinal symptoms (such as diarrhea, dyspepsia, and vomiting), as well as photosensitivity and skin rashes, particularly associated with Pirfenidone. In cases where the side effects are extremely severe and are more threatening than the disease itself, the treatment has to be discontinued. However, further research is needed to optimize the use of antifibrotic agents in patients with PF-ILDs, which could slow disease progression and decrease all-cause mortality. Finally, other studies are requested to establish the treatments that can stop ILD progression. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Vascular Endothelial Damage in COPD: Where Are We Now, Where Will We Go?

Author

Screm, Gianluca, Mondini, Lucrezia, Salton, Francesco, Confalonieri, Paola, Trotta, Liliana, Barbieri, Mariangela, Romallo, Antonio, Galantino, Alessandra, Hughes, Michael, Lerda, Selene, Confalonieri, Marco, and Ruaro, Barbara

Subjects
CHRONIC obstructive pulmonary disease, RETINAL blood vessels, ENDOTHELIUM diseases
Abstract

Background: Chronic obstructive pulmonary disease (COPD) has higher rates among the general population, so early identification and prevention is the goal. The mechanisms of COPD development have not been completely established, although it has been demonstrated that endothelial dysfunction plays an important role. However, to date, the measurement of endothelial dysfunction is still invasive or not fully established. Nailfold video capillaroscopy (NVC) is a safe, non-invasive diagnostic tool that can be used to easily evaluate the microcirculation and can show any possible endothelial dysfunctions early on. The aim of this review is to evaluate if nailfold microcirculation abnormalities can reflect altered pulmonary vasculature and can predict the risk of cardiovascular comorbidities in COPD patients. Methods: A systematic literature search concerning COPD was performed in electronic databases (PUBMED, UpToDate, Google Scholar, ResearchGate), supplemented with manual research. We searched in these databases for articles published until March 2024. The following search words were searched in the databases in all possible combinations: chronic obstructive pulmonary disease (COPD), endothelial damage, vascular impairment, functional evaluation, capillaroscopy, video capillaroscopy, nailfold video capillaroscopy. Only manuscripts written in English were considered for this review. Papers were included only if they were able to define a relationship between COPD and endothelium dysfunction. Results: The search selected 10 articles, and among these, only three previous reviews were available. Retinal vessel imaging, flow-mediated dilation (FMD), and skin autofluorescence (AF) are reported as the most valuable methods for assessing endothelial dysfunction in COPD patients. Conclusions: It has been assumed that decreased nitric oxide (NO) levels leads to microvascular damage in COPD patients. This finding allows us to assume NVC's potential effectiveness in COPD patients. However, this potential link is based on assumption; further investigations are needed to confirm this hypothesis. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Oscillometry Longitudinal Data on COVID-19 Acute Respiratory Syndrome Treated with Non-Invasive Respiratory Support.

Author

Torregiani, Chiara, Baratella, Elisa, Segalotti, Antonio, Ruaro, Barbara, Salton, Francesco, Confalonieri, Paola, Tavano, Stefano, Lapadula, Giulia, Bozzi, Chiara, Confalonieri, Marco, Dellaca', Raffaele L., and Veneroni, Chiara

Subjects
COVID-19, PANEL analysis, PSYCHOLOGICAL reactance, SYNDROMES, HOSPITAL admission & discharge
Abstract

Background: Oscillometry allows for the non-invasive measurements of lung mechanics. In COVID-19 ARDS patients treated with Non-Invasive Oxygen Support (NI-OS), we aimed to (1) observe lung mechanics at the patients' admission and their subsequent changes, (2) compare lung mechanics with clinical and imaging data, and (3) evaluate whether lung mechanics helps to predict clinical outcomes. Methods: We retrospectively analyzed the data from 37 consecutive patients with moderate–severe COVID-19 ARDS. Oscillometry was performed on their 1st, 4th, and 7th day of hospitalization. Resistance (R5), reactance (X5), within-breath reactance changes (ΔX5), and the frequency dependence of the resistance (R5–R19) were considered. Twenty-seven patients underwent computed tomographic pulmonary angiography (CTPA): collapsed, poorly aerated, and normally inflated areas were quantified. Adverse outcomes were defined as intubation or death. Results: Thirty-two patients were included in this study. At the first measurement, only 44% of them had an abnormal R5 or X5. In total, 23 patients had measurements performed on their 3rd day and 7 on their 7th day of hospitalization. In general, their R5, R5–R19, and ΔX decreased with time, while their X5 increased. Collapsed areas on the CTPA correlated with the X5 z-score (ρ = −0.38; p = 0.046), while poorly aerated areas did not. Seven patients had adverse outcomes but did not present different oscillometry parameters on their 1st day of hospitalization. Conclusions: Our study confirms the feasibility of oscillometry in critically ill patients with COVID-19 pneumonia undergoing NI-OS. The X5 z-scores indicates collapsed but not poorly aerated lung areas in COVID-19 pneumonia. Our data, which show a severe impairment of gas exchange despite normal reactance in most patients with COVID-19 ARDS, support the hypothesis of a composite COVID-19 ARDS physiopathology. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation

Author

Ring, Nadja Anneliese Ruth, Volpe, Maria Concetta, Stepišnik, Tomaž, Mamolo, Maria Grazia, Panov, Panče, Kocev, Dragi, Vodret, Simone, Fortuna, Sara, Calabretti, Antonella, Rehman, Michael, Colliva, Andrea, Marchesan, Pietro, Camparini, Luca, Marcuzzo, Thomas, Bussani, Rossana, Scarabellotto, Sara, Confalonieri, Marco, Pham, Tho X., Ligresti, Giovanni, Caporarello, Nunzia, Loffredo, Francesco S., Zampieri, Daniele, Džeroski, Sašo, and Zacchigna, Serena

Published
2022
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27. Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS

Author

Meduri, Gianfranco Umberto, Annane, Djillali, Confalonieri, Marco, Chrousos, George P., Rochwerg, Bram, Busby, Amanda, and Ruaro, Barbara

Subjects
Methylprednisolone -- Analysis, Corticosteroids -- Analysis, Health care industry
Abstract

Current literature addressing the pharmacological principles guiding glucocorticoid (GC) administration in ARDS is scant. This paucity of information may have led to the heterogeneity of treatment protocols and misinterpretation of available findings. GCs are agonist compounds that bind to the GC receptor (GR) producing a pharmacological response. Clinical efficacy depends on the magnitude and duration of exposure to GR. We updated the meta-analysis of randomized trials investigating GC treatment in ARDS, focusing on treatment protocols and response. We synthesized the current literature on the role of the GR in GC therapy including genomic and non-genomic effects, and integrated current clinical pharmacology knowledge of various GCs, including hydrocortisone, methylprednisolone and dexamethasone. This review addresses the role dosage, timing of initiation, mode of administration, duration, and tapering play in achieving optimal response to GC therapy in ARDS. Based on RCTs' findings, GC plasma concentration-time profiles, and pharmacodynamic studies, optimal results are most likely achievable with early intervention, an initial bolus dose to achieve close to maximal GR[alpha] saturation, followed by a continuous infusion to maintain high levels of response throughout the treatment period. In addition, patients receiving similar GC doses may experience substantial between-patient variability in plasma concentrations affecting clinical response. GC should be dose-adjusted and administered for a duration targeting clinical and laboratory improvement, followed by dose-tapering to achieve gradual recovery of the suppressed hypothalamic-pituitary-adrenal (HPA) axis. These findings have practical clinical relevance. Future RCTs should consider these pharmacological principles in the study design and interpretation of findings., Author(s): Gianfranco Umberto Meduri [sup.1] [sup.8], Djillali Annane [sup.2], Marco Confalonieri [sup.3], George P. Chrousos [sup.4], Bram Rochwerg [sup.5] [sup.9], Amanda Busby [sup.6], Barbara Ruaro [sup.3], Bernd Meibohm [sup.7] Author [...]

Published
2020
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30. Predicting individualized treatment effects of corticosteroids in community-acquired-pneumonia: a data-driven analysis of randomized controlled trials

Author

Smit, Jim M., primary, van der Zee, Philip A., additional, Stoof, S. C.M., additional, van Genderen, Michel E., additional, Snijders, Dominic, additional, Boersma, Wim G., additional, Confalonieri, Paola, additional, Salton, Francesco, additional, Confalonieri, Marco, additional, Shih, Mei-Chiung, additional, Meduri, Gianfranco U., additional, Dequin, Pierre-Francois, additional, Le Gouge, Amelie, additional, Lloyd, Melanie, additional, Karunajeewa, Harin, additional, Bartminski, Grzegorz, additional, Fernandez-Serrano, Silvia, additional, Suarez-Cuartin, Guillermo, additional, van Klaveren, David, additional, Briel, Matthias, additional, Schoenenberger, Christof M., additional, Steyerberg, Ewout W., additional, Gommers, Diederik A.M.P.J., additional, Bax, Hannelore I., additional, Bos, W J W., additional, van de Garde, Ewoudt, additional, Wittermans, Esther, additional, Grutters, Jan C., additional, Blum, Claudine A., additional, Christ-Crain, Mirjam, additional, Torres, Antoni, additional, Motos, Anna, additional, Reinders, Marcel J.T., additional, van Bommel, Jasper, additional, Krijthe, Jesse H., additional, and Endeman, Henrik, additional

Published
2023
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31. Accuracy of right atrial pressure estimation using a multi-parameter approach derived from inferior vena cava semi-automated edge-tracking echocardiography: a pilot study in patients with cardiovascular disorders

Author

Albani, Stefano, Pinamonti, Bruno, Giovinazzo, Tatiana, de Scordilli, Marco, Fabris, Enrico, Stolfo, Davide, Perkan, Andrea, Gregorio, Caterina, Barbati, Giulia, Geri, Pietro, Confalonieri, Marco, Lo Giudice, Francesco, Aquaro, Giovanni D., Pasquero, Paolo, Porta, Massimo, Sinagra, Gianfranco, and Mesin, Luca

Published
2020
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32. An international perspective on hospitalized patients with viral community-acquired pneumonia

Author

Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic-Carevic, Vesna, Jakopovic, Marko, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Bødtger, Uffe, Meyer, Christian Niels, Vestergaard Jensen, Andreas, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Salvi, Sundeep, Limaye, Sneha, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d’Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F., Medenica, Milic, van de Garde, E.M.W., Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N.O., Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B., Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González Del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F.M., Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hancock, Carole, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Franco-Sadud, Ricardo A., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J., Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Angel, Luis F., Anzueto, Antonio, Scott Whitlow, K., Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Radovanovic, Dejan, Sotgiu, Giovanni, Jankovic, Mateja, Mahesh, Padukudru Anand, Marcos, Pedro Jorge, Abdalla, Mohamed I., Di Pasquale, Marta Francesca, Gramegna, Andrea, Terraneo, Silvia, Blasi, Francesco, Santus, Pierachille, Aliberti, Stefano, Reyes, Luis F., and Restrepo, Marcos I.

Published
2019
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33. Biomarkers in Systemic Sclerosis: An Overview

Author

Di Maggio, Giuseppe, primary, Confalonieri, Paola, additional, Salton, Francesco, additional, Trotta, Liliana, additional, Ruggero, Luca, additional, Kodric, Metka, additional, Geri, Pietro, additional, Hughes, Michael, additional, Bellan, Mattia, additional, Gilio, Michele, additional, Lerda, Selene, additional, Baratella, Elisa, additional, Confalonieri, Marco, additional, Mondini, Lucrezia, additional, and Ruaro, Barbara, additional

Published
2023
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34. Pulmonary Sarcoidosis and Immune Dysregulation: A Pilot Study on Possible Correlation

Author

Cifaldi, Rossella, primary, Salton, Francesco, additional, Confalonieri, Paola, additional, Trotta, Liliana, additional, Barbieri, Mariangela, additional, Ruggero, Luca, additional, Valeri, Gianmaria, additional, Pozzan, Riccardo, additional, Della Porta, Rossana, additional, Kodric, Metka, additional, Baratella, Elisa, additional, Bellan, Mattia, additional, Lerda, Selene, additional, Hughes, Michael, additional, Confalonieri, Marco, additional, Cova, Maria Assunta, additional, Gandin, Ilaria, additional, Mondini, Lucrezia, additional, and Ruaro, Barbara, additional

Published
2023
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35. Clinical profile in patients with severe alpha-1 antitrypsin deficiency due to rare genotypes

Author

Ottaviani, Stefania, primary, Piloni, Davide, additional, Filosa, Asia, additional, Barzon, Valentina, additional, Balderacchi, Alice Maria, additional, Corda, Luciano, additional, Seebacher, Christine, additional, Corino, Alessandra, additional, Magni, Sara, additional, Mariani, Francesca, additional, Baderna, Paolo, additional, Confalonieri, Marco, additional, Iannacci, Leonardo, additional, Mancinelli, Silvia, additional, Putignano, Paola, additional, Stella, Giulia Maria, additional, Monti, Maria Cristina, additional, Corsico, Angelo Guido, additional, and Ferrarotti, Ilaria, additional

Published
2023
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39. 184 Complement score: A novel prognostic tool in malignant pleural mesothelioma?

Author

Balduit, Andrea, primary, Mangogna, Alessandro, additional, Vaira, Valentina, additional, Agostinis, Chiara, additional, Rafaniello Raviele, Paola, additional, Bottin, Cristina, additional, Salton, Francesco, additional, Nesa, Francesco, additional, Fusco, Nicola, additional, Ferrero, Stefano, additional, Zanconati, Fabrizio, additional, Confalonieri, Marco, additional, and Bulla, Roberta, additional

Published
2023
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40. 178 Complement component C1q can predict patients’ response to cisplatin depending on tumour type: A step towards personalized medicine?

Author

Balduit, Andrea, primary, Mangogna, Alessandro, additional, Agostinis, Chiara, additional, Salton, Francesco, additional, Toffoli, Miriam, additional, Zito, Gabriella, additional, Romano, Federico, additional, Verardo, Roberto, additional, Confalonieri, Marco, additional, Ricci, Giuseppe, additional, and Bulla, Roberta, additional

Published
2023
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41. Epithelioid Mesothelioma Patients with Very Long Survival Display Defects in DNA Repair

Author

Ganzinelli, Monica, primary, Guffanti, Federica, additional, Ianza, Anna, additional, Sobhani, Navid, additional, Crovella, Sergio, additional, Zanconati, Fabrizio, additional, Bottin, Cristina, additional, Confalonieri, Marco, additional, Fumagalli, Stefano, additional, Guglielmi, Alessandra, additional, Generali, Daniele, additional, and Damia, Giovanna, additional

Published
2023
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42. Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia : Systematic Review and Individual Patient Data Metaanalysis

Author

Ovidius Study Group, Capisce Study Group, and STEP Study Group, Briel, Matthias, Spoorenberg, Simone M. C., Snijders, Dominic, Torres, Antoni, Fernandez-Serrano, Silvia, Meduri, G. Umberto, Gabarrús, Albert, Blum, Claudine A., Confalonieri, Marco, Kasenda, Benjamin, Siemieniuk, Reed A.C., Boersma, Wim, Bos, Willem Jan W., and Christ-Crain, Mirjam

Published
2018

46. Infection control, genetic assessment of drug resistance and drug susceptibility testing in the current management of multidrug/extensively-resistant tuberculosis (M/XDR-TB) in Europe: A tuberculosis network European Trialsgroup (TBNET) study

Author

Albrecht, Dirk, Anibarro, Luis, Gomez, Neus Altet, Andersen, Aase Bengaard, Avsar, Korkut, Balasanyants, Goar, Belton, Moerida, García, Cristina Berastegui, Bogyi, Matthias, Bruchfeld, Judith, Caminero, Jose, Chesov, Dumitru, Chiappini, Elena, Confalonieri, Marco, Dedicoat, Martin, Luiza de Souza Galvao, Maria, Duarte, Raquel, Dudnyk, Andrii, Dyrhol-Riise, Anne Ma, Eisenhut, Michael, Esteban, Jaime, Fløe, Andreas, García-García, José-María, Giacomet, Vania, Gomez-Pastrana, David, Gyorfy, Zsuzsanna, Holmoka, Jiri, Jachym, Mathilde Fréchet, Janssens, Jean-Paul, Jonsson, Jerker, Kaluzhenina, Anna, Konstantynovska, Olha, Kruczak, Katarzyna, Ladeira, Inês, Kuksa, Liga, Kulcitkaia, Stela, Lillebæk, Troels, Magis-Escurra, Cecile, Manika, Katerina, Joan-Pau, Millet, Muylle, Inge, Palmieri, Fabrizio, Pesut, Dragica, Polanova, Monika, Pontali, Emanuele, Popa, Cristina, Ravn, Pernille, Sánchez-Montalvá, Adrian, Schoch, Otto, Selmeryd, Ingrid, Skrahina, Alena, Solovic, Ivan, Soriano-Arandes, Antoni, Thouvenin, Guillaume, Tiberi, Simon, Wagner, Dirk, van der Werf, Tjip, van Ingen, Jakko, Vicente, Diego, Volchenkov, Grigory, Woltmann, Gerrit, Bothamley, Graham H., and Lange, Christoph

Published
2017
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47. Theory and Practice of Glucocorticoids in COVID-19: Getting to the Heart of the Matter—A Critical Review and Viewpoints

Author

Salton, Francesco, primary, Confalonieri, Paola, additional, Meduri, Gianfranco Umberto, additional, Mondini, Lucrezia, additional, Trotta, Liliana, additional, Barbieri, Mariangela, additional, Bozzi, Chiara, additional, Torregiani, Chiara, additional, Lerda, Selene, additional, Bellan, Mattia, additional, Confalonieri, Marco, additional, Ruaro, Barbara, additional, Tavano, Stefano, additional, and Pozzan, Riccardo, additional

Published
2023
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48. Host-Based Treatments for Severe COVID-19

Author

Mondini, Lucrezia, primary, Salton, Francesco, additional, Trotta, Liliana, additional, Bozzi, Chiara, additional, Pozzan, Riccardo, additional, Barbieri, Mariangela, additional, Tavano, Stefano, additional, Lerda, Selene, additional, Hughes, Michael, additional, Confalonieri, Marco, additional, Confalonieri, Paola, additional, and Ruaro, Barbara, additional

Published
2023
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