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11. Predictors of complications and mortality following left colectomy with primary stapled anastomosis for cancer: results of a multicentric study with 1111 patients

Author

Pellino, G., Frasson, M., García-Granero, A., Granero-Castro, P., Ramos Rodríguez, J. L., Flor-Lorente, B., Bargallo Berzosa, J., Alonso Hernández, N., Labrador Vallverdú, F. J., Parra Baños, P. A., Ais Conde, G., Garcia-Granero, E., Alvarez Rico, Miguel Angel, García Brao, Maria Jesus, Sanchez Gonzalez, Juan Manuel, Braithwaite, Mariela, Martí Martínez, Eva, Álvarez Pérez, Jose Antonio, Espí, Alejandro, Trallero, A., Millán Scheiding, Mónica, Maseda Díaz, Olga, Dujovne Lindenbaum, Paula, Monzón Abad, Andrés, Romero Simó, Manuel, Escoll Rufino, Jordi, Santamaría Olabarrieta, Marta, Viñas Martínez, José, López Bañeres, Manolo, Blesa Sierra, Isabel, Feliú Villaró, Francesc, Lucía, Javier Aguiló, Codina Cazador, Antonio, Villalba, Juan Hernandis, Álvarez Laso, Carlos, Alcaide, Sonia Martínez, Cáceres Alvarado, Maria Nieves, Simó, Ignacio Rey, Montero García, Josep, García Fadrique, Alfonso, Aguilella Diago, Vicente, García Septiem, Javier, García, Jacinto García, Ponchietti, Luca, Carceller Navarro, Maria Soledad, Ramos Fernández, María, Conde Muiño, Raquel, Huerga Álvarez, Daniel, Sánchez, Pablo Menéndez, Maristany Bienert, Carlos, García Martínez, Maria Teresa, Muzas, Celia Moreno, Pastor Idoate, Carlos, Alonso Casado, Adolfo Pedro, Roig Vila, Jose Vicente, Goded Broto, Ignacio, Collera, Pablo, Sebastián, Antonio Arroyo, Pellino, G., Frasson, M., García-Granero, A., Granero-Castro, P., Ramos Rodríguez, J. L., Flor-Lorente, B., Bargallo Berzosa, J., Alonso Hernández, N., Labrador Vallverdú, F. J., Parra Baños, P. A., Ais Conde, G., Garcia-Granero, E., Alvarez Rico, Miguel Angel, García Brao, Maria Jesu, Sanchez Gonzalez, Juan Manuel, Braithwaite, Mariela, Martí Martínez, Eva, Álvarez Pérez, Jose Antonio, Espí, Alejandro, Trallero, A., Millán Scheiding, Mónica, Maseda Díaz, Olga, Dujovne Lindenbaum, Paula, Monzón Abad, André, Romero Simó, Manuel, Escoll Rufino, Jordi, Santamaría Olabarrieta, Marta, Viñas Martínez, José, López Bañeres, Manolo, Blesa Sierra, Isabel, Feliú Villaró, Francesc, Lucía, Javier Aguiló, Codina Cazador, Antonio, Villalba, Juan Hernandi, Álvarez Laso, Carlo, Alcaide, Sonia Martínez, Cáceres Alvarado, Maria Nieve, Simó, Ignacio Rey, Montero García, Josep, García Fadrique, Alfonso, Aguilella Diago, Vicente, García Septiem, Javier, García, Jacinto García, Ponchietti, Luca, Carceller Navarro, Maria Soledad, Ramos Fernández, María, Conde Muiño, Raquel, Huerga Álvarez, Daniel, Sánchez, Pablo Menéndez, Maristany Bienert, Carlo, García Martínez, Maria Teresa, Muzas, Celia Moreno, Pastor Idoate, Carlo, Alonso Casado, Adolfo Pedro, Roig Vila, Jose Vicente, Goded Broto, Ignacio, Collera, Pablo, and Sebastián, Antonio Arroyo

Subjects
Male, medicine.medical_specialty, Colectomies, Databases, Factual, Colorectal cancer, Colon, anastomotic leak, 030230 surgery, Lower risk, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Risk Factors, Surgical Stapling, medicine, Humans, stapled anastomosi, postoperative complication, Prospective Studies, left colectomy, Colectomy, Aged, business.industry, Anastomosis, Surgical, Gastroenterology, Postoperative complication, Perioperative, Middle Aged, medicine.disease, Surgery, Colon cancer, Parenteral nutrition, Treatment Outcome, 030220 oncology & carcinogenesis, Colonic Neoplasms, Female, business, Complication
Abstract

Aim Reports detailing the morbidity-mortality after left colectomy are sparse and do not allow definitive conclusions to be drawn. We aimed to identify risk factors for anastomotic leakage, perioperative mortality and complications following left colectomy for colonic malignancies. Method We undertook a STROBE-compliant analysis of left colectomies included in a national prospective online database. Forty-two variables were analysed as potential independent risk factors for anastomotic leakage, postoperative morbidity and mortality. Variables were selected using the 'least absolute shrinkage and selection operator' (LASSO) method. Results We analysed 1111 patients. Eight per cent of patients had a leakage and in 80% of them reoperation or surgical drainage was needed. A quarter of patients (24.9%) experienced at least one minor complication. Perioperative mortality was 2%, leakage being responsible for 47.6% of deaths. Obesity (OR 2.8, 95% CI 1.00-7.05, P = 0.04) and total parenteral nutrition (TPN) (OR 3.7, 95% CI 1.58-8.51, P = 0.002) were associated with increased risk of leakage, whereas female patients had a lower risk (OR 0.36, 95% CI 0.18-0.67, P = 0.002). Corticosteroids (P = 0.03) and oral anticoagulants (P = 0.01) doubled the risk of complications, which was lower with hyperlipidaemia (OR 0.3, P = 0.02). Patients on TPN had more complications (OR 4.02, 95% CI 2.03-8.07, P = 0.04) and higher mortality (OR 8.7, 95% CI 1.8-40.9, P = 0.006). Liver disease and advanced age impaired survival, corticosteroids being the strongest predictor of mortality (OR 21.5, P = 0.001). Conclusion Requirement for TPN was associated with more leaks, complications and mortality. Leakage was presumably responsible for almost half of deaths. Hyperlipidaemia and female gender were associated with lower rates of complications. These findings warrant a better understanding of metabolic status on perioperative outcome after left colectomy.

Published
2018

17. Protocolo del estudio: abordaje del sobrepeso en Atención Primaria: papel de la entrevista motivacional

Author

Gorrotxategi Gorrotxategi, P., Leizaola Olarreaga, L., Solorzano Sánchez, C., García Conde, G., Aguirre Sorondo, B., Totoricaguena Imaz, A., Caballero Barrigón, M. J., and Cancio López, H.

Subjects
Sobrepeso infantil, Hábitos dietéticos, Physical activity, Dietary habits, Motivational interviewing, Sedentary lifestyle, Entrevista motivacional, Child overweight, Atención Primaria, Primary care, Nutrición, Actividad física, Sedentarismo, Nutrition
Abstract

Objetivo: plantear un programa de intervención sobre el sobrepeso, desarrollado por los profesionales de Atención Primaria (AP), basado en la entrevista motivacional. Analizar las variaciones del z score del índice de masa corporal (IMC), del patrón nutricional, del nivel de actividad física y la concordancia entre dos diferentes escalas para ese fin. Metodología: diseño: estudio de intervención en niños entre 6 y 12 años que en el control del programa de salud infantil de los seis años tengan un IMC >P85 y 85th percentile and < 95th percentile). Children with secondary obesity or those who would not be properly followed-up will be excluded from the study. Asix-sessioninterventionbased onmotivational interviewing, will be performed. A nutritionand physical activityquestionnaire will be administered at baseline, at 4months andat the end oftheintervention. Factors associated to pre-post changes will be studied via multivariate regression models. The agreement between the physical activity questionnaires will be assessed with the Kappa coefficient. Statistical analysis will be performed using SPSS version 21. The greatest limitation of this study is the lack of skills for motivational interviewing among the participating clinicians. To address this limitation, the participating clinicians will attend specific workshops on motivational interviewing focused on child obesity. Another limitation is the lack of a control group.

Published
2014

18. Anxiety and depressive symptomatology among children and adolescents exposed to the COVID-19 pandemic: A systematic review

Author

Đurđević Sanja, Conde Ghigliazza Ileana, Dukanac Vesna, and Đurđević Ana

Subjects
adolescent, anxiety, child, covid-19, depression, Medicine (General), R5-920
Abstract

Background/Aim. Children and adolescents are sensitive groups for the development of mental disorders during the crisis. The aim of this systematic review was to assess the impact of the COVID-19 pandemic on anxiety and depressive symptomatology in the population of children and adolescents. Methods. The investigation was based on a systematic review followed by PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) protocol, including Ovid MEDLINE, Embase, Global Health, and APA Psyc Info databases, to identify relevant studies reporting anxiety and depressive symptoms among children and adolescents during the COVID-19 pandemic. A total of 27 articles were included. Results. Anxiety symptoms increased from 28.3% before the pandemic to 49.5% during confinement [General Anxiety Disorder (GAD)-7 ≥ 11)] (McNemar test, p < 0.0001). More depressive symptomatology was found, as well as weight and sleep disturbances which are the characteristics of children and adolescents’ mental health. Additionally, female teenagers were experiencing grater declines in mood disorders than male teenagers during the COVID-19 crisis. On the one hand, different positive correlations between anxiety and other variables, were found, such as clinical depressive symptoms and anxiety (3/14), smartphone and internet addiction (2/14), lower levels of family income (2/14), perceived threats (2/14), higher grades at school (2/14), and loneliness (1/14). On the other hand, positive correlations were reported between depression and children and adolescents that were socially disconnected (3/17). Finally, mothers with higher level of education and income were associated with higher level of happiness (2/17). Conclusion. COVID-19 has a strong impact on the mental health of children and adolescents regarding depression and anxiety symptoms. Prevention programs focused on coping strategies should be conducted in elementary schools, middle schools, and high schools. Mental health should become a priority matter for governments, and the current pandemic could be an opportunity to highlight the importance of mental well-being and to invest in the betterment of clinical trainings, treatments and mental health research.

Published
2022
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20. Nuevo tratamiento para la vejiga hiperactiva

Author

Rebassa Llull, Miguel, Conde, G., Cholvi, M., Briones, G., Mus Malleu, Alfredo, Blasco, M., Fuentes, I., Hidalgo Pardo, Félix, and Gutiérrez Sanz-Gadea, Carlos

Subjects
Urinary incontinence
Published
2007

35. General discussion.

Author

Davies, D. W., del Conde, G., Lin, S. M., Grice, R., McDonald, J. D., Polanyi, J. C., Schreiber, J. L., Whitehead, J. C., Dixon, D. A., King, D. L., Herschbach, D. R., Cheung, J. T., Marcus, R. A., Parson, J. M., Shobatake, K., Lee, Y. T., Rice, S. A., Carter, C. F., Levy, M. R., and Woodall, K. B.

Published
1973
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36. UHF study of multibody effects in small lithium clusters and their relevance to atom-surface interactions

Author

Conde, G. del, García-Prieto, J., and Novaro, O.

Abstract

An unrestricted Hartree-Fock (UHF) study of multibody non-additive effects on various lithium clusters, proposed as models of the Li (100) surface, is presented. Non-additive terms are used as a reliable guide to cluster stabilities and their adsorption capacities. Three- and four-body terms are shown to be of equal sign and comparable magnitude, thus suggesting a slow convergence of the multibody expansion of the interaction energy for the lithium surface.

Published
1981
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39. A novel application of Fiber Bragg Grating (FBG) sensors in MPGD

Author

Abbaneo D., Abbas M., Abbrescia M., Abi Akl M., Aboamer O., Acosta D., Ahmad A., Ahmed W., Aleksandrov A., Altieri P., Asawatangtrakuldee C., Aspell P., Assran Y., Awan I., Bally S., Ban Y., Banerjee S., Barashko V., Barria P., Bencze G., Beni N., Benussi L., Bhopatkar V., Bianco S., Bos J., Bouhali O., Braghieri A., Braibant S., Buontempo S., Calabria C., Caponero M., Caputo C., Cassese F., Castaneda A., Cauwenbergh S., Cavallo F.R., Celik A., Choi M., Choi S., Christiansen J., Cimmino A., Colafranceschi S., Colaleo A., Conde Garcia A., Czellar S., Dabrowski M.M., De Lentdecker G., De Oliveira R., de Robertis G., Dildick S., Dorney B., Endroczi G., Errico F., Fenyvesi A., Ferrini M., Ferry S., Furic I., Giacomelli P., Gilmore J., Golovtsov V., Guiducci L., Guilloux F., Gutierrez A., Hadjiiska R.M., Hauser J., Hoepfner K., Hohlmann M., Hoorani H., Iaydjiev P., Jeng Y.G., Kamon T., Karchin P., Korytov A., Krutelyov S., Kumar A., Kim H., Lalli A., Lee J., Lenzi T., Litov L., Loddo F., Madorsky A., Maerschalk T., Maggi M., Magnani A., Mal P.K., Mandal K., Marchioro A., Marinov A., Majumdar N., Merlin J.A., Mitselmakher G., Mohanty A.K., Mohapatra A., Molnar J., Muhammad S., Mukhopadhyay S., Naimuddin M., Nuzzo S., Oliveri E., Pant L.M., Paolucci P., Park I., Passamonti L., Passeggio G., Pavlov B., Philipps B., Piccolo D., Pierluigi D., Postema H., Primavera F., Puig Baranac A., Radi A., Radogna R., Raffone G., Ranieri A., Rashevski G., Riccardi C., Rodozov M., Rodrigues A., Ropelewski L., RoyChowdhury S., Russo A., Ryu G., Ryu M.S., Safonov A., Salva S., Saviano G., Sharma A., Sharma R., Shah A.H., Shopova M., Sturdy J., Sultanov G., Swain S.K., Szillasi Z., Talvitie J., Tatarinov A., Tuuva T., Tytgat M., Valente M., Vai I., Van Stenis M., Venditti R., Verhagen E., Verwilligen P., Vitulo P., Volkov S., Vorobyev A., Wang D., Wang M., Yang U., Yang Y., Yonamine R., Zaganidis N., Zenoni F., and Zhang A.

Subjects
Physics, QC1-999
Abstract

We present a novel application of Fiber Bragg Grating (FBG) sensors in the construction and characterisation of Micro Pattern Gaseous Detector (MPGD), with particular attention to the realisation of the largest triple (Gas electron Multiplier) GEM chambers so far operated, the GE1/1 chambers of the CMS experiment at LHC. The GE1/1 CMS project consists of 144 GEM chambers of about 0.5 m2 active area each, employing three GEM foils per chamber, to be installed in the forward region of the CMS endcap during the long shutdown of LHC in 2108-2019. The large active area of each GE1/1 chamber consists of GEM foils that are mechanically stretched in order to secure their flatness and the consequent uniform performance of the GE1/1 chamber across its whole active surface. So far FBGs have been used in high energy physics mainly as high precision positioning and re-positioning sensors and as low cost, easy to mount, low space consuming temperature sensors. FBGs are also commonly used for very precise strain measurements in material studies. In this work we present a novel use of FBGs as flatness and mechanical tensioning sensors applied to the wide GEM foils of the GE1/1 chambers. A network of FBG sensors have been used to determine the optimal mechanical tension applied and to characterise the mechanical tension that should be applied to the foils. We discuss the results of the test done on a full-sized GE1/1 final prototype, the studies done to fully characterise the GEM material, how this information was used to define a standard assembly procedure and possible future developments.

Published
2018
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40. Quality control for the first large areas of triple-GEM chambers for the CMS endcaps

Author

Abbaneo D., Abbas M., Abbrescia M., Abi Akl M., Aboamer O., Acosta D., Ahmad A., Ahmed W., Aleksandrov A., Altieri P., Asawatangtrakuldee C., Aspell P., Assran Y., Awan I., Bally S., Ban Y., Banerjee S., Barashko V., Barria P., Bencze G., Beni N., Benussi L., Bhopatkar V., Bianco S., Bos J., Bouhali O., Braghieri A., Braibant S., Buontempo S., Calabria C., Caponero M., Caputo C., Cassese F., Castaneda A., Cauwenbergh S., Cavallo F.R., Celik A., Choi M., Choi S., Christiansen J., Cimmino A., Colafranceschi S., Colaleo A., Conde Garcia A., Czellar S., Dabrowski M.M., De Lentdecker G., De Oliveira R., de Robertis G., Dildick S., Dorney B., Endroczi G., Errico F., Fenyvesi A., Ferry S., Furic I., Giacomelli P., Gilmore J., Golovtsov V., Guiducci L., Guilloux F., Gutierrez A., Hadjiiska R.M., Hauser J., Hoepfner K., Hohlmann M., Hoorani H., Iaydjiev P., Jeng Y.G., Kamon T., Karchin P., Korytov A., Krutelyov S., Kumar A., Kim H., Lee J., Lenzi T., Litov L., Loddo F., Madorsky A., Maerschalk T., Maggi M., Magnani A., Mal P.K., Mandal K., Marchioro A., Marinov A., Majumdar N., Merlin J.A., Mitselmakher G., Mohanty A.K., Mohapatra A., Molnar J., Muhammad S., Mukhopadhyay S., Naimuddin M., Nuzzo S., Oliveri E., Pant L.M., Paolucci P., Park I., Passeggio G., Pavlov B., Philipps B., Piccolo D., Postema H., Puig Baranac A., Radi A., Radogna R., Raffone G., Ranieri A., Rashevski G., Riccardi C., Rodozov M., Rodrigues A., Ropelewski L., RoyChowdhury S., Ryu G., Ryu M.S., Safonov A., Salva S., Saviano G., Sharma A., Sharma R., Shah A.H., Shopova M., Sturdy J., Sultanov G., Swain S.K., Szillasi Z., Talvitie J., Tatarinov A., Tuuva T., Tytgat M., Vai I., Van Stenis M., Venditti R., Verhagen E., Verwilligen P., Vitulo P., Volkov S., Vorobyev A., Wang D., Wang M., Yang U., Yang Y., Yonamine R., Zaganidis N., Zenoni F., and Zhang A.

Subjects
Physics, QC1-999
Abstract

The CMS Collaboration plans to equip the very forward muon system with triple-GEM detectors that can withstand the environment of the High-Luminosity LHC. This project is at the final stages of R&D and moving to production. An unprecedented large area of several 100 m2 are to be instrumented with GEM detectors which will be produced in six different sites around the world. A common construction and quality control procedure is required to ensure the performance of each detector. The quality control steps will include optical inspection, cleaning and baking of all materials and parts used to build the detector, leakage current tests of the GEM foils, high voltage tests, gas leak tests of the chambers and monitoring pressure drop vs. time, gain calibration to know the optimal operation region of the detector, gain uniformity tests, and studying the efficiency, noise and tracking performance of the detectors in a cosmic stand using scintillators.

Published
2018
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42. Pasatiempos

Author

Fuente, B. A. de la, ed. lit, Imprenta de El Nacional, imp, Conde, G. L. de, Fuente, B. A. de la, ed. lit, Imprenta de El Nacional, imp, and Conde, G. L. de

Abstract

Marca tip. en port

Published
1896

45. General discussion

Author

Loesch, H. J., primary, Carley, J. S., additional, Zandee, L., additional, Reuss, J., additional, Le Roy, R. J., additional, Child, M. S., additional, Dixon, D. A., additional, Herschbach, D. R., additional, Klemperer, W., additional, Whitehead, R. J., additional, Swaminathan, S., additional, Guth, E., additional, Beveridge, D. L., additional, Kutzelnigg, W., additional, Murrell, J. N., additional, Freed, K. F., additional, Hase, W. L., additional, Longuet-Higgins, H. C., additional, Mulder, J. J. C., additional, Engelke, F., additional, Whitehead, J. C., additional, Zare, R. N., additional, Estler, R. C., additional, Lubman, D., additional, George, T. F., additional, Gorry, Peter A., additional, Grice, Roger, additional, Polanyi, J. C., additional, Schreiber, J. L., additional, Skrlac, W. J., additional, Bagus, P. S., additional, del Conde, G., additional, Davies, D. W., additional, Hillier, I. H., additional, Wyatt, R. E., additional, McNutt, J. A., additional, Latham, S. L., additional, Redmon, M. J., additional, Jakubetz, W., additional, Connor, J. N. L., additional, Fraser, S. J., additional, Komornicki, A., additional, Morokuma, K., additional, Blackwell, B. A., additional, Sloan, J. J., additional, Ungemach, S. R., additional, Schaefer, H. F., additional, Liu, B., additional, Klimek, D. E., additional, Ding, A., additional, Aquilanti, V., additional, Luiti, G., additional, Pirani, F., additional, Vecchiocattivi, F., additional, Volpi, G. G., additional, Lawley, K. P., additional, Costello, J., additional, Fluendy, M. A. D., additional, and Dewar, M. J. S., additional

Published
1977
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