Search

Your search keyword '"Colombo, M. G."' showing total 74 results
Start Over Author "Colombo, M. G."
74 results on '"Colombo, M. G."'

12. Sales and employment changes in entrepreneurial ventures with family ownership:empirical evidence from high-tech industries

Author

Colombo, M. G., De Massis, Alfredo, Piva, E., Rossi-Lamastra, C., Wright, M., Colombo, M. G., De Massis, Alfredo, Piva, E., Rossi-Lamastra, C., and Wright, M.

Abstract

We examine the relation between changes in employment and changes in sales for entrepreneurial ventures with and without family ownership. We argue that this positive relation is weaker for entrepreneurial ventures with family ownership. The goal of preserving socio-emotional wealth (SEW) makes indeed these firms more reluctant to hire (fire) employees in correspondence with an increase (decrease) in sales than their counterparts without family ownership. Results on a sample of Italian entrepreneurial ventures in high-tech industries support our arguments. They also show that the strength of the relation depends on the composition of the entrepreneurial team.

Published
2014

44. Evidence for association of a common variant of the endothelial nitric oxide synthase gene (Glu298↠Asp polymorphism) to the presence, extent, and severity of coronary artery disease.

Author

Colombo, M. G., Andreassi, M. G., Paradossi, U., Botto, N., Manfredi, S., Masetti, S., Rossi, G., Clerico, A., and Biagini, A.

Subjects
*NITRIC-oxide synthases, *GENES, *GENETIC polymorphisms, *POLYMERASE chain reaction, *ANGIOGRAPHY, *CORONARY disease
Abstract

Background: Genetic variants of endothelial nitric oxide synthase (eNOS) could influence individual susceptibility to coronary artery disease. Objective: To assess whether GIu298 → Asp polymorphism of the eNOS gene is associated with the occurrence and severity of angiographically defined coronary artery disease in the Italian population. Methods: Polymerase chain reaction/restriction fragment length polymorphism analysis was done to detect the Glu298 → Asp variant of the eNOS gene in 201 patients with coronary artery disease and 114 controls. The severity of coronary artery disease was expressed by the number of affected vessels and by the Duke scoring system. Results: The frequencies of the eNOS Glu/Glu, Glu/Asp, and Asp/Asp genotypes in the coronary artery disease group were significantly different from those of controls (45.3%, 38.8%, and 15.9% v 42.1%, 51.8%, and 6.1%, respectively; χ² = 8.589, p = 0.0136). In comparison with subjects who had a Glu298 allele in the eNOS gene, the risk of coronary artery disease was increased among Asp/Asp carriers (odds ratio 2.9, 95% confidence interval 1.2 to 6.8, p = 0.01) and was independent of the other common risk factors (p = 0.04). There was a significant association between the eNOS Glu298→Asp variant and both the number of stenosed vessels (mean (SEM), 2.3 (0.1) for Asp/Asp v 1.9 (0.1) and 1.8 (0.1) for Glu/Glu and Glu/Asp, respectively; p = 0.01) and the Duke score (56.1 (3.1) for Asp/Asp v 46.7 (2.0) and 46.1 (1.9) for Glu/Glu and Glu/Asp respectively; p = 0.02). Conclusions: Glu298→Asp polymorphism of the eNOS gene appears to be associated with the presence, extent, and severity of angiographically assessed coronary artery disease. [ABSTRACT FROM AUTHOR]

Published
2002
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results