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This study identified the relationship between energy balance and some blood metabolites in primiparous dairy cows with different calving conception interval. Twenty primiparous Holstein-Friesian dairy cows were grouped according to the interval (days) from calving to conception into early-conception (early-c; <100 days), mid-conception group (mid-c; 100 -- 150 days) or late-conception (late-c; >150 days) group; and evaluated on day -7 prior to parturition, and days 28, 56 and 90 postpartum. All groups presented positive energy balance, serum concentrations of HDL, urea-N and progesterone with no difference on days 28 and 56 of lactation. On day 90 of lactation all the cows presented negative energy balance; however, the early-c group presented a less intense (P < 0.05) net energy balance (-1.09 versus -2.15 and -1.86 Mcal/day), lower concentrations of serum urea-N (3.28 versus 4.22 and 4.88 mg/dL) and HDL cholesterol (0.84 versus 1.59 and 1.46 mmol/L) and greater serum concentration of progesterone (8.13 versus 4.54 and 1.83 ng/mL) than cows of mid-c and late-c groups, respectively. In conclusion, different from those usually observed for multiparous dairy cows, the energy balance during the first weeks of lactation was not a determining factor affecting the calving conception interval of primiparous dairy cows in the present study. Instead, the nutritional status and the serum concentration of urea-N and progesterone at a later stage, after 56 days of lactation, suggest having a role in delaying these cows' pregnant status. [ABSTRACT FROM AUTHOR]

Atherosclerotic cardiovascular disease (ASCVD) remains the major cause of premature death and disability; effective cardiovascular (CV) risk prevention is fundamental. The World Heart Federation (WHF) Cholesterol Roadmap provides a framework for national policy development and aims to achieve ASCVD prevention.At the invitation of the WHF, a group of experts from the Portuguese Society of Cardiology (SPC), addressed the cholesterol burden at nationally and discussed possible strategies to include in a Portuguese cholesterol roadmap. The literature review showed that the cholesterol burden in Portugal is high and especially uncontrolled in those with the highest CV risk. An infographic scorecard was built to include in the WHF collection, for a clear idea about CV risk and cholesterol burden in Portugal, which would also be useful for health policy advocacy.The expert discussion and preventive strategies proposal followed the five pillars of the WHF document: awareness improvement; population-based approaches for CV risk and cholesterol; risk assessment/population screening; system-level approaches; surveillance of cholesterol and ASCVD outcomes. These strategies were debated by all the expert participants, with the goal of creating a national cholesterol roadmap to be used for advocacy and as a guide for CV prevention.Several key recommendations were outlined: include all stakeholders in a multidisciplinary national program; create a structured activities plan to increase awareness in the population; improve the quality of continuous CV health education; increase the interaction between different health professionals and non-health professionals; increment the referral of patients to cardiac rehabilitation; screen cholesterol levels in the general population, especially high-risk groups; promote patient self-care, engage with patients’ associations; use specific social networks to spread information widely; create a national database of cholesterol levels with systematic registry of CV events; redefine strategies based on the evaluation of results; create and involve more patients’ associations – invert the pyramid order.In conclusion, ASCVD and the cholesterol burden remain a strong global issue in Portugal, requiring the involvement of multiple stakeholders in prevention. The Portuguese cholesterol roadmap can provide some solutions to help urgently mitigate the problem. Population-based approaches to improve awareness and CV risk assessment and surveillance of cholesterol and ASCVD outcomes are key factors in this change. A call to action is clearly needed to fight hypercholesterolemia and ASCVD burden. Resumo: A doença aterosclerótica cardiovascular (DACV) mantém-se a maior causa de morte prematura e de incapacidade, sendo uma prevenção eficaz de risco cardiovascular (CV) fundamental. O WHF Cholesterol Roadmap fornece enquadramento para o desenvolvimento de políticas nacionais, tendo como objetivo a prevenção de DACV. A convite da WHF, um grupo de peritos da Sociedade Portuguesa de Cardiologia (SPC) avaliou a carga do colesterol a nível nacional e discutiu possíveis estratégias para um Roadmap português.A revisão da literatura mostrou uma carga elevada de colesterol em Portugal, sobretudo em pessoas de alto risco CV. Uma infografia, Scorecard, foi construída pela WHF, para mostrar claramente o risco CV e o peso do colesterol em Portugal, sendo útil para advocacia em políticas de saúde.A discussão de peritos e proposta das estratégias preventivas seguiram os cinco pilares do documento da WHF: Melhoria da consciencialização; Abordagens do risco CV e do colesterol nas populações; Avaliação de risco/screening das populações; abordagens a nível do sistema; Seguimento do colesterol e complicações da DACV.Várias recomendações chave foram definidas: incluir todos os stakeholders em programa multidisciplinar nacional; criar plano de atividades estruturadas para aumentar a consciencialização da população; aumentar qualidade da educação contínua em saúde CV; aumentar interação entre profissionais de saúde e outros profissionais; aumentar referenciação de doentes para reabilitação cardiovascular; avaliar níveis de colesterol na população geral, especialmente em alto risco; promover autocuidado dos doentes, envolvendo associações de doentes; usar redes sociais específicas para disseminar informação; criar base nacional de níveis de colesterol com registo sistemático de eventos CV; redefinir estratégias baseadas na avaliação de resultados; criar e envolver mais doentes em associações – inverter a ordem da pirâmide!Em conclusão, a DACV e o peso de colesterol permanecem uma questão global forte em Portugal, necessitando o envolvimento de múltiplos stakeholders na prevenção. O Roadmap de colesterol português pode fornecer algumas soluções para urgentemente mitigar o problema. Abordagens a nível das populações para melhorar a consciencialização e avaliar o risco CV, seguimento do colesterol e das complicações de DACV são fatores chave nesta mudança. Uma call to action é claramente necessária para combater a carga da hipercolesterolemia e DACV.

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Minas Frescal cheese is a relevant nutritional source in the diet, and its consumption is expressive and growing. However, the unsaturated fatty acids and cholesterol present in its lipid fraction are susceptible to oxidation, with implications for health issues, due to quality losses and the formation of harmful compounds for consumers. Due to the importance of dairy products associated with the enhancement of food quality and clean production practices, it is important to the lipid fraction, identifying the composition of fatty acids and cholesterol content. The food industry uses different strategies for the use of antioxidants to reduce lipid oxidation and increase shelf life. Herbs and spices are natural ingredients widely used not only as a food flavoring but also for their health attributes. The present study is a literature review on the lipid composition of Minas Frescal cheese and the use of natural additives to protect against lipid oxidation. Thus, the use of vegetable sources in Minas Frescal cheese, in addition to providing flavor, aroma, and color, is an option for natural preservatives to replace synthetic additives, and presents antioxidant, antimicrobial, and anticancer compounds, with protective potential against undesirable reactions, corroborating to consumer demand for healthy food.

Background: the aim of this randomized placebo-controlled study was to investigate the effect of probiotics mainly on plasma lipids, homocysteine levels, glycemic biomarkers and inflammatory marker in people with hyperlipidemia, compared to a placebo. Methods: a randomized, double-blind placebo-controlled study was completed with a total of 51 men and women who have diagnosed with hyperlipidemia. The three study interventions were: 1) probiotic group I asked to take once a day 1 x 106 colony forming unit (CFU) Lactobacillus rhamnosus GG microorganism (n = 18) capsule; 2) probiotic group II asked to take once a day of a combined Lactobacillus acidophilus 1 x 109 CFU and Bifidobacterium animalis subsp. lactis 1 x 109 CFU probiotic capsule (n = 17); and 3) placebo group: emptied capsule (n = 16), plasma lipids, homocysteine, and glycemic biomarkers were were performed at baseline and week 8. Also, hs-CRP levels was assessed as inflammatory parameter. Results: compared to baseline there was a significant decrease in triglyceride and total cholesterol levels of the both intervention groups compared to the placebo group. Regarding the glycemic biomarkers. both intervention groups significantly alter the HOMA-IR values compared to the placebo group (p < 0.05). When homocysteine values were evaluated. a statistically significant decrease was observed only in the group using the combined strain (p < 0.05). Results demonstrated that regular and strain-specific use of probiotics have effective and favorable consequences on plasma lipids and glycemic biomarkers. Conclusion: probiotics containing Lactobacillus or Bifidobacterium could be effective in hypercholesterolemic patients, reducing serum lipids as well as homocysteine and glycaemia. [ABSTRACT FROM AUTHOR]

Copyright of Revista Latinoamericana de Hipertension is the property of Revista Latinoamericana de Hipertension and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Selva Andina Animal Science is the property of Fundacion Selva Andina Research Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Romanian Journal of Nutrition is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Los ácidos biliares son biomoléculas con esqueleto esteroidal presentes en la bilis animal y humana, sintetizada en el hígado, a partir de la descomposición del colesterol y luego metabolizados por el microbiota intestinal. Se les atribuyen propiedades biológicas, farmacológicas, anticancerígena, antimicrobiana y terapéuticas; también exhiben efectos bacteriostáticos y bactericidas afectando a géneros, como Staphylococcus, Balantidium, Pneumococcus y Enterococcus; sin embargo, hay pocos estudios con actividad antioxidante apreciable. Por lo tanto, se extrajeron e identificaron químicamente los ácidos biliares aislados de la bilis de bovino (Bos), para determinar su potencial antioxidante y bactericida. Los ácidos biliares fueron derivatizados como ésteres metílicos y analizados mediante cromatografía de gases, acoplada a espectrometría de masas. La actividad bactericida se evaluó frente a Staphylococcus aureus y Pseudomona aeruginosa por el método de microdilución, con concentraciones entre 250 - 4000 μg/mL. El potencial antioxidante fue evaluado frente al radical libre 2,2-difenil-1-picrilhidracilo, a una concentración de 100 μg/mL. Los resultados mostraron la presencia de tres ácidos biliares: ácidos cólicos, ácido desoxicólico y ácido 7alfa-hidroxi-3-oxo-colan-24-oico. La inhibición del crecimiento bacteriano se alcanzó, en su totalidad, con los dos microorganismos evaluados, aún a la concentración más baja utilizada (250 μg/mL). La actividad antioxidante de los ácidos biliares frente al radical DPPH fue muy baja, presentándose un potencial de reducción de 8,9 % a la concentración utilizada. Esta investigación permitió contribuir con el estudio de las actividades biológicas y químicas de los ácidos biliares.

Aim: Metabolic syndrome increases the risk of diabetes and cardiovascular disease. Recent studies on the prevalence of metabolic syndrome in Peru have focused on specific populations without national representativeness. Material and Methods: Cross-sectional analysis of a national health survey. Metabolic syndrome was defined according to the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF). The prevalence of metabolic syndrome was described according to sociodemographic variables, as well as its most frequent individual components and their predicted cardiovascular risk. Results: We included 917 participants aged 18-59 years. The prevalence of metabolic syndrome was 46% according to the NCEP ATP III criteria and 57% according to the IDF criteria. According to both criteria, prevalence of metabolic syndrome was higher in women, people aged 40-59 years, and people from urban areas. ~60% of the population with metabolic syndrome met 3 criteria, and 96% had low HDL, 79% hyperglycemia, and 77% abdominal obesity. The predicted cardiovascular risk was higher in those meeting all 5 criteria (3,9%) than 3 criteria (1.8%). Conclusions: Metabolic syndrome affects 1 in 2 adults in Peru and is more frequent in women, older people, and urban population. Of every 10 Peruvians with metabolic syndrome, 6 meet 3 components and only 1 meet all 5 components. The most frequent components are low HDL, hyperglycemia, and abdominal obesity. [ABSTRACT FROM AUTHOR]

Copyright of Revista Cientifica de la Facultade de Veterinaria is the property of Universidad del Zulia, Facultad de Ciencias Veterinarias and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas is the property of Universidad de Santiago de Chile and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Atherosclerosis constitutes the leading cause of death worldwide, surpassing violence. Given the physiopathological complexity it presents, it is important to recognize the genetic and atherogenic alterations associated with its development biology, which is useful for the prevention and control of obstructive vascular disease. The genetic inheritance pattern and the availability of candidate genes, such as PCSK9, APOB, APOA5, APOC3, ApoE, ABCA1, LPA, involved in the synthesis and metabolism of lipoproteins, show the possibility of establishing biomarkers related to alterations in plasma levels, demonstrating their risk association in different populations, which allows the identification of potential therapeutic targets. [ABSTRACT FROM AUTHOR]

Primary Biliary Cholangitis (PBC) is a multifactorial autoimmune disease influenced by genetic factors and environmental triggers such as geographic location, smoking, microorganisms, xenobiotics. This study aims to elucidate the risk factors associated with PBC and its impact on cardiovascular risk. A comprehensive literature search was conducted across databases including original research, prospective and retrospective cohort studies, case-control studies, systematic reviews, and meta-analyses, utilizing relevant keywords. Evidence suggests a correlation between PBC related alterations in the lipid profile, increased oxidative stress, and endothelial dysfunction; however, studies attempting to determine the effect of hypercholesterolemia on the increase in Cardio Vascular Risk (CVR) in patients with PBC have yield contradictory results. Hepatic steatosis is associated with an elevated risk of Cardiovascular Disease (CV D) and is common in chronic liver diseases such as chronic hepatitis B and C, as well as non-alcoholic fatty liver disease. PBC can manifest extrahepatically, with pulmonary conditions such as interstitial lung disease and pulmonary hypertension being among the most prevalent. This article explores the relationship between PBC and its primary risk factors, as well as the development of both hepatic and extrahepatic conditions contributing cardiovascular risk. [ABSTRACT FROM AUTHOR]

Triglicéridos en ayunas >100 mg / dl se encuentran asociados con Resistencia a la Insulina y dislipidemia aterogenica Objetivo: evaluar el aumento de triglicéridos postprandiales tomando como base triglicéridos en ayuna con valores mayores y menores de 100 mg|dL , en pacientes despues de su desayuno habitual y correlacionarlos con Resistencia a la insulina medida por HOMA y Colesterol y sus fracciones asi como Colesterol No HDL y Colesterol Remanente Método: Estudio descriptivo de corte transversal, con una población de pacientes de la consulta de Endocrinología del Hospital Militar Dr. Carlos Arvelo de Caracas. Las muestras fueron tomadas en ayuna y a las 2 horas depués de una comida, y se dividieron los pacientes en 2 grupos según trigliceridos mayores o menores de 100mg/dl Resultados: Los pacientes con trigliceridos menores de 100mg/dl presentaron triglicéridos a las 2 horas menores a 150mg/dl, en los dos grupos los triglicéridos subieron en promedio 49 mg/dl. El colesterol no HDL, el colesterol remanente y el HOMA estaban más alto estadísticamente significativos en los pacientes con triglicéridos basales mayores a 100 mg/dl así como el HDL colesterol era menor en pacientes. Conclusiones: en nuestro estudio los triglicéridos por debajo de 100mg/dl se acompañaban de HDL colesterol alto mientras los valores de triglicéridos por encima de 100m/dl se acompañaban de HDL colesterol bajo, mayor HOMA, mayor colesterol remanente y mayor colesterol No HDL

Introduction: Rafts are protein-lipid structural nanodomains involved in efficient signal transduction and the modulation of physiological processes of the cell plasma membrane. Raft disruption in the nervous system has been associated with a wide range of disorders. Development: We review the concept of rafts, the nervous system processes in which they are involved, and their role in diseases such as Parkinson’s disease, Alzheimer disease, and Huntington disease. Conclusions: Based on the available evidence, preservation and/or reconstitution of rafts is a promising treatment strategy for a wide range of neurological disorders. Resumen: Introducción: Los rafts constituyen nanodominios estructurales de naturaleza lipo-proteica que propician la eficiente transducción de señales y la modulación de procesos fisiológicos asociados a la membrana plasmática. En el sistema nervioso, la alteración de estos dominios se ha asociado con el desarrollo de diversos padecimientos. Desarrollo: En el presente artículo se revisa el concepto de rafts, los procesos del sistema nervioso en los cuales están involucrados y su papel en distintas afectaciones, entre las que se destacan las enfermedades de Parkinson, Alzheimer y Huntington. Conclusiones: Dadas las evidencias de su participación en diversas neuropatías, la preservación y/o reconstitución de los rafts se vislumbran como una atractiva estrategia terapéutica.

Cardiovascular diseases (CVD) continue to be the main cause of death in our country. Adequate control of lipid metabolism disorders is a key challenge in cardiovascular prevention that is far from being achieved in real clinical practice. There is a great heterogeneity in the reports of lipid metabolism from Spanish clinical laboratories, which may contribute to its poor control. For this reason, a working group of the main scientific societies involved in the care of patients at vascular risk, has prepared this document with a consensus proposal on the determination of the basic lipid profile in cardiovascular prevention, recommendations for its realization and unification of criteria to incorporate the lipid control goals appropriate to the vascular risk of the patients in the laboratory reports. Resumen: Las enfermedades cardiovasculares (ECV) siguen siendo la principal causa de muerte en nuestro pais. El control adecuado de las alteraciones del metabolismo lipidico es un reto clave en prevencion cardiovascular que esta lejos de alcanzarse en la practica clinica real. Existe una gran heterogeneidad en los informes del metabolismo lipidico de los laboratorios clinicos españoles, lo que puede contribuir al mal control del mismo. Por ello, un grupo de trabajo de las principales sociedades cientificas implicadas en la atencion de los pacientes de riesgo vascular hemos elaborado este documento con una propuesta basica de consenso sobre la determinacion del perfil lipidico basico en prevencion cardiovascular, recomendaciones para su realizacion y unificacion de criterios para incorporar los objetivos de control lipidico adecuados al riesgo vascular de los pacientes en los informes de laboratorio.

Copyright of Revista de la Facultad de Medicina Humana is the property of Instituto de Investigaciones en Ciencias Biomedicas de la Universidad Ricardo Palma and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Nutrición Clínica y Dietética Hospitalaria is the property of Sociedad Espanola de Dietetica y Ciencias de la Alimentacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de la Asociación Odontológica Argentina is the property of Asociacion Odontologica Argentina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Las enfermedades cardiovasculares (ECV) siguen siendo la principal causa de muerte en nuestro país. El control adecuado de las alteraciones del metabolismo lipídico es un reto clave en prevención cardiovascular que está lejos de alcanzarse en la práctica clínica real. Existe una gran heterogeneidad en los informes del metabolismo lipídico de los laboratorios clínicos españoles, lo que puede contribuir al mal control del mismo. Por ello, un grupo de trabajo de las principales sociedades científicas implicadas en la atención de los pacientes de riesgo vascular hemos elaborado este documento con una propuesta básica de consenso sobre la determinación del perfil lipídico básico en prevención cardiovascular, recomendaciones para su realización y unificación de criterios para incorporar los objetivos de control lipídico adecuados al riesgo vascular de los pacientes en los informes de laboratorio.

Cholesterol crystal embolism is the effect of the destabilization of an atherosclerotic plaque after a triggering event, producing the migration of cholesterol crystals to peripheral arterioles, triggering an endothelial inflammatory process; the clinical spectrum varies from being asymptomatic to having multiple organ involvement; diagnostic suspicion is mainly clinical and the skin biopsy will confirm the diagnosis due to its easy accessibility. The treatment is still controversial and there is no consensus on the therapeutic measures to apply. Below is the case of a 72-year-old male patient with atheroembolism due to cholesterol crystals in the lower limbs, secondary to endovascular manipulation by prior angioplasty. [ABSTRACT FROM AUTHOR]

This research aimed to evaluate the profile of fatty acids (saturated, monounsaturated and polyunsaturated) and the cholesterol of lamb meat from the crossing of breeds Santa Inês x Dorper handled in the Campomar Farm and subjected to production systems with Experimental and Conventional diet. We used six lambs from the crossing of Santa Inês x Dorper with experimental diet and 6 without experimental diet, uncastrated male, recently weaned with 15 kg of body weight according to completely randomized design with two treatments and six repetitions. Comparisons of the contrasts between treatment averages were made by the Tukey test at 5% and the analysis of variance according to procedures of SAS (1996). The experimental diet provided to the animals was composed of 100% concentrate in the diet consisting of grain corn + pelleted supplement, sodium chloride, calcium carbonate, dicalcium phosphate and vitamin and mineral supplements, making isoproteic (17% of PB) and isoenergetic (2.95 Mcal/kg of MS of metabolizable energy) diets, according to NRC (2006), while in the conventional diet, the animals were fed large (50%) and concentrate (50%) corn, wheat and soybeans. In the centesimal composition of the palette of lambs subjected to experimental and conventional production systems, only the mineral matter was influenced (P<0.05) with lower value in the experimental system (1.09%) compared to the conventional (1.43%). For the parameters moisture, gross protein and fat and cholesterol (P>0.05) there was no effect of treatments. It was observed that the saturated and monounsaturated fatty acids were not affected (P> 0.05) by the treatments, however, the polyunsaturated fatty acid C18:2 (linoleic) was higher (4.72%) in the meat of lambs from the experimental system compared to (3.72%) observed in the meat of lambs reared in the conventional system. The palette of lambs subjected to experimental production and conventional systems, was similar on centesimal composition (exception mineral matter), no significant differences in two treatments studied, the fatty acid profile and cholesterol (with the exception of linoleic acid) in the two treatments evaluated in the palette. [ABSTRACT FROM AUTHOR]

Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista do Instituto de Laticínios Cândido Tostes is the property of Revista do Instituto de Laticinios Candido Tostes and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objetivo. Determinar la efectividad de la intervención nutricional en los beneficiarios de comedores populares de Lima, 2022. Métodos. El estudio fue de tipo aplicativo, diseño experimental específicamente pre-experimental (sin grupo control) y de corte longitudinal. La población estuvo conformada por todos los benefciarios de los comedores populares de San Luis. La muestra estuvo constituida por 110 benefciarios de comedores populares. Resultados. El diagnostico nutricional cambió de manera positiva. Con respecto a la evaluación antropométrica, la mediana del IMC disminuyó de 27,95 a 26,04; el CMB disminuyó de 30,05 a 28,20 y el PAB disminuyó de 90,00 a 88,00. En relación a los valores bioquímicos, la mediana del nivel de colesterol disminuyó de 190,20 a 184,10; el nivel de glucosa disminuyó de 99,30 a 92,40 y el nivel de hemoglobina disminuyó de 13,30 a 13,20. En relación a la impedancia bioeléctrica, el porcentaje de grasa disminuyó de 34,00 a 31,00 y el porcentaje de agua aumento de 47,00 a 48,00. El valor de p = 0,00 fue menor de 0,05; por lo tanto, el cambio obtenido después de la intervención nutricional es signifcativo. Con respecto a la hemoglobina el valor de p = 0,06 fue mayor de 0,05; por ende, el cambio no fue signifcativo. Conclusiones. La intervención nutricional causó efecto signifcativo en el estado nutricional defnido por antropometría, análisis bioquímico e impedancia bioeléctrica

El impacto de los cambios bioquímicos en el adulto mayor tiene el mismo factor en común ya que, presentan alteraciones en su vejez y los descritos se ven en el metabolismo de la glucosa como: morfológicos y funcionales. Los primeros se asocian a un aumento de grasa visceral, infiltración grasa de tejidos y menor masa de células beta, los segundos se observan en una mayor producción de adipocinas factores inflamatorios, al igual que, una mayor resistencia insulínica y diabetes. Los cambios en el metabolismo lipídico fluctúan y alteran las lipoproteínas, colesterol y triglicéridos; se puede evidenciar al medir dichos analitos séricos provocando así dislipidemias. La investigación está enfocada en identificar los principales cambios bioquímicos en los análisis de glucosa y perfil lipídico (colesterol, triglicéridos, HDL y LDL) en una población de 89 adultos mayores de la provincia de Tungurahua, Ecuador, a través de un estudio con diseño descriptivo, transversal, de campo. Mediante el software Minitab versión 18.1, se pudo determinar que con un intervalo de confianza del 95% no existen cambios en los analitos de glucosa, colesterol total, HDL y LDL. Por otra parte, con un intervalo de confianza del 95% del 100%, el 14% pueden tener un valor sobre los 150mg/dL en el analito de triglicéridos tanto en hombres como en mujeres. El porcentaje de pacientes con tendencia a padecer cambios bioquímicos es relativamente bajo en nuestra investigación, por lo que se ha determinado como un factor protector la actividad física que desarrollan los pacientes del estudio dado su forma de trabajo, pese a ello se destaca a la hipertrigliceridemia en un 14%. Asimismo, un alto porcentaje de pacientes geriátricos manifiesta haber desarrollado diabetes en un 64% (n= 57), pero demuestran un escaso conocimiento de la enfermedad, ya que dicen padecerla, pero no se refleja en los resultados de laboratorio que presenten tal enfermedad.

Introducción. La hipercolesterolemia familiar (HcF) es una patología causada por diversas mutaciones con una incidencia variable dependiendo de su forma heterocigota u homocigota. Sin embargo, pocos casos son diagnosticados y no todo el personal de salud conoce sobre la enfermedad. Materiales y Método. Se realizó una encuesta en línea basada en Google Forms para medir el nivel de conocimiento del personal de salud sobre la HcF en la República Dominicana. Se utilizó un cuestionario confeccionado por los autores basado en los criterios DUCTH de hipercolesterolemia. Resultados. El predominio del personal de salud que llenó el cuestionario fue de nutriólogos; el conocimiento sobre los valores de corte adecuado para el diagnóstico de HcF fue reportado en 30% de la muestra. Conclusiones. Es imperativo incrementar el conocimiento del personal de salud sobre HcF con el objetivo de disminuir la muerte cardiovascular prematura.

Ficou experimentalmente comprovado que os fosfolipideos retardam e o colesterol e seus derivados aceleram a formação de tumores induzidos por hidrocarbonetos cancerígenos. Acentua-se a suma importância deste fenômeno, pois trata-se de dois grupos de lipídeos comuns, aliás componentes naturais de qualquer célula animal, capazes de influenciar, positivamente, o mecanismo da carcinogênese. O fato de que os fosfolipideos e o colesterol, ao lado das proteínas, constituem quantitativamente os componentes principais da membrana celular, conduziu ao raciocínio lógico que as membranas devem representar uma posição chave na etiologia do câncer.

Objetivo: definir a ação do licopeno sob CT, HDL, LDL e TG e analisar quais dosagens suficientes que apresentam efeito positivo nos marcadores metabólicos. Metodologia: A investigação foi baseada no efeito dos produtos contendo licopeno e seu efeito nos marcadores metabólicos séricos de Colesterol total, LDL, HDL e Triglicerídeos. Para análise de estudos in vivo foram incluídos estudos que preenchiam critérios de intervenção com delineamento controlado, dieta ou manipulado controlado por placebo cruzado ou paralelo, ensaio clínico randomizado com dosagem padronizada de licopeno no tratamento e grupo controle e intervenção 2≤ semanas que avaliaram colesterol total, HDL, LDL e triglicerídeos. Resultados: Foi visto que o licopeno apresenta importante atuação sobre marcadores metabólicos isto devido a sua capacidade de reduzir o mecanismo de HMG-Coa redutase, diminuindo a síntese de colesterol e sua capacidade antioxidante sob LDL. O licopeno também modulou a atividade de PPAR e LXR, modulando ação de ABCA1, Apoa1 e caveolinas melhorando a síntese de HDL e efluxo de colesterol. As dosagens com efeito positivo de colesterol variam, mas ficam em torno de 26,5 mg de licopeno por dia, relatado em estudos in vivo com suplementação de colesterol. Conclusão: A revisão sugere a eficácia do licopeno na redução de marcadores metabólicos, reduzindo assim riscos de doenças ateroscleróticas.

Introdução: A melhor composição da dieta no tratamento da obesidade é ainda bastante controversa, tendo em vista que a composição ideal para a perda e manutenção de peso é ainda desconhecida, e entre essa busca pela melhor estratégia vem se destacando como as mais populares atualmente as dietas restritas em carboidratos. Cada vez mais se tem buscado novos tipos de dietas e estratégias nutricionais para solucionar esses problemas que a obesidade causa e cada profissional busca uma linha da nutrição para se basear. Objetivo: Investigar se a prescrição de uma dieta com baixo teor de carboidratos possui efeitos sobre o emagrecimento e redução da concentração de lipídeos séricos e glicose em um indivíduo obeso. Materiais e Métodos: Estudo de caso com tipo de abordagem qualitativa, com natureza de pesquisa aplicada, realizado durante um mês com um indivíduo que estava na condição de obesidade submetido a uma dieta com 25% de carboidrato por dia. Resultados: Houve uma perda de seis kg, redução de 3,5% do percentual de gordura, quatro cm de cintura, cinco cm de abdominal e quatro cm de quadril. Todos os parâmetros bioquímicos tiveram uma melhora considerável, mas destaca-se a redução do colesterol total que reduziu 26,33%, seguido da glicemia que obteve redução de 21,73%. Os triglicerídeos tiveram uma redução de 21,13%. Conclusão: Torna-se mais evidente que uma dieta com baixo teor de carboidrato é uma alternativa eficaz para perda de peso, melhora do perfil lipídico e glicêmico.

Una cacatúa ninfa (Nymphicus hollandicus), hembra de 10 años, que fallece súbitamente durante la consulta médica, fue evaluada, histopatológicamente, en el laboratorio Unidad de Diagnóstico en Patología Aviar, Escuela de Medicina Veterinaria, Universidad Nacional. En la evaluación, post-mortem, macroscópicamente, destaca el hallazgo de engrosamiento, tortuosidad y múltiples nodulaciones de la aorta ascendente, en sus bifurcaciones y otras arterias en la base del corazón. El estudio histopatológico revela diversos grados de lesiones arteriales causadas por aterosclerosis. En este reporte, se describe y caracteriza las lesiones histológicas además, se realiza una revisión de las medidas preventivas, métodos diagnósticos y tratamientos disponibles para manejo de esta patología en aves de Costa Rica.

El objetivo de la presente investigación fue monitorear en las cuatro estaciones del año, el estado nutricional de cabras en tres etapas fisiológicas. La investigación se realizó en Tlahualilo, Durango de agosto 2014 a julio de 2015. Muestreos sanguíneos se hicieron en cabras para determinar las concentraciones de glucosa, colesterol, proteína total y nitrógeno ureico. Los grupos estudiados fueron cabras en producción (PROD), gestación (GES) y desarrollo (DES), factor uno; en invierno, primavera, verano y otoño, factor dos, en un diseño completamente al azar con arreglo factorial. La glucosa en invierno del grupo PROD con 45.81 mg dL−1 fue la menor concentración (p < .05). La DES en invierno de 57.71 mg dL−1 fue la más baja (p < .05) en colesterol. La PROD en invierno tuvo de proteína 58.74 mg dL−1 , la menor concentración (p < .05). El nitrógeno ureico encontrado también fue menor en invierno (p < .05). Los parámetros sanguíneos fueron más bajos en invierno.

Introducción. Las heridas crónicas suponen un grave problema de salud con gran impacto socioeconómico debido a su morbimortalidad y a la afectación de la calidad de vida. Desde hace tiempo se conocen las propiedades de los lípidos en el sistema inmunitario. Un sistema inmunológico débil podría conducir a una infección o cronificación de las heridas. El colesterol es un lípido con importancia cuantitativa en las membranas de las células donde contribuye al mantenimiento de la fluidez de membrana. Unos niveles bajos de colesterol se relacionan con mayor riesgo de padecer infecciones. El objetivo del estudio fue analizar los niveles de lípidos en pacientes con úlceras por presión infectadas. Metodología. Se estudiaron 77 pacientes del Departamento de Salud de Elche Hospital General con úlceras por presión infectadas en un periodo de un año. Resultados. Se ponen de manifiesto diferencias estadísticamente significativas entre pacientes con niveles de C-LDL por debajo de 70mg/dL y pacientes con niveles por encima de 70mg/dL que presentan un CT por debajo de 140mg/dL. Discusión. La investigación futura sobre estos aspectos ayudará a aclarar los mecanismos de transporte del colesterol hacia los tejidos para así protegerlos de las agresiones de los microorganismos. ABSTRACT Introduction. Chronic wounds are a serious health problem with great socioeconomic impact due to their morbidity and mortality and the affectation of quality of life. The properties of lipids in the immune system have been known for a long time. A weak immune system could lead to infection or chronic wounds. Cholesterol is a quantitatively important lipid in cell membranes where it contributes to maintaining membrane fluidity. Low levels of cholesterol are associated with an increased risk of infections. The objective of the study was to analyze the levels of lipids in patients with pressure ulcers infected. Methodology. 77 patients with infections in pressure ulcers from the Health Department of Elche-General Hospital were studied for one year. Results. Statistically significant differences are revealed between patients with LDL-C levels below 70mg/dL and patients with levels above 70mg/dL. Levels of TC were below 140mg/dL in both groups. Discussion. Future research on these aspects will help clarify the mechanisms of cholesterol transport to the tissues and therefore protect them from microorganism aggressions.

Introduction: Metabolic syndrome is defined as a set of clinical conditions that affect approximately 25% of the world's population and 29.6% of Brazilians. This syndrome is related to increased cardiovascular outcomes, which may be predicted by the lipid profile. Bioactive compounds, such as monounsaturated fatty acids (MUFAs), are strong allies in preventing these outcomes. Avocado is an important food because it contains abundant bioactive compounds and MUFAs. However, few studies evaluated the effects of pure/virgin avocado oil on the lipid profile in humans with metabolic syndrome, and its effects on atherogenic indices are not known. Objective: This study evaluated avocado oil supplementation on lipid levels and atherogenic indices in patients with metabolic syndrome. Method: Thirty-one obese adults were randomised into a control group (soybean oil) and an intervention group (avocado oil). These groups were evaluated in the pre- and post-intervention periods (12 weeks) via clinical anamnesis and nutritional assessment. Results: The control group and the intervention group had higher intakes of lipids and saturated fat than recommended. For the lipid profile and atherogenic indices, no significant difference was observed between the pre- and postintervention periods. Conclusion: These results may have been due to the absence of dietary control, medication overload, intervention duration, mode of administration and dose of the supplement. Therefore, future studies on the effects of avocado oil are needed in this population to better control these variables. [ABSTRACT FROM AUTHOR]

Dyslipidemia is considered a risk factor for the development of insulin resistance and cardiovascular diseases, such as left ventricular hypertrophy and remodeling of the arterial wall. Resveratrol, present in grapes, has been studied as a possible mediator of cardiovascular protection. The present study aimed to evaluate the effect of red wine from the Merlot grape (Vitis vinifera L.) on dyslipidemia and its involvement in male mice, knockout for the LDL receptor gene (LDLR-/-). The mice were divided into 4 experimental groups: Group S received standard rodent food; Group SV received standard feed for rodents and wine; Group HL received high fat diet; Group HLV received hyperlipidic food and wine orally for 60 days. All animals received water and food ad libitum during this period. After this period, they remained fasting and were then anesthetized. Blood was collected for serum analysis of triglycerides, total cholesterol, and its fractions (HDL and VLDL), C-reactive protein, glucose, and insulin to compare the data. Morphometric and histological analyzes of the left ventricle and abdominal aorta were also performed. It was found that Merlot red wine has antidyslipidemic effects on genetic dyslipidemia, associated with food, partially preventing insulin resistance, hyperinsulinemia and increased CRP; as well as cardiovascular effect, partially preventing LVH and arterial remodeling. [ABSTRACT FROM AUTHOR]

Copyright of Ecosistemas y Recursos Agropecuarios is the property of Universidad Juarez Autonoma de Tabasco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Selva Andina Animal Science is the property of Fundacion Selva Andina Research Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Cardiovascular disease is one of the main causes of morbidity and mortality worldwide. Control of its risk factors, particularly diabetes and dyslipidemia, through reduction of LDL cholesterol, is crucial to reduce cardiovascular risk. This work aims to assess and improve the medical approach to dyslipidemia in diabetic patients. Methods: This is a quality improvement study aimed at family doctors. It included patients with diabetics and dyslipidemia enrolled in the primary health care units of Além D’Ouro, S. Miguel and Oceanos. A quality standard was defined for each of the criteria assessed, and the results were compared using the chi-square test with p-value

Diversas semillas de oleaginosas son fuente de ácidos grasos esenciales indispensables para cubrir las funciones básicas en el organismo. El estudio tuvo como objetivo evaluar el efecto de la inclusión de semilla de linaza (Linum usitatissimum)en la dieta de conejos por medio del perfil metabólico. Se utilizaron 20 machos de la raza Nueva Zelandia de 8 meses de edad. Distribuidos en cuatro grupos, recibieron niveles de semilla de linaza (L. usitatissimum) en la dieta total: 0%, 3%, 6% y9%, durante un período de 88 días. Los animales se sometieron a colecta de sangre cada 22 días para determinar glucosa, colesterol total, lipoproteínas de alta densidad (HDL), triglicéridos, lipoproteínas de muy baja densidad (VLDL), lipoproteínas de baja densidad (LDL), creatinina y urea. Los datos se evaluaron por análisis de varianza y de regresión con 5% de significancia. La inclusión de semilla de linaza (L. usitatissimum) en la dieta presentó comportamiento cuadrático positivo para concentración plasmática de glucosa y colesterol total. No hubo diferencia significativa entre los tratamientos para la concentración plasmática detriglicéridos, lipoproteínas de baja densidad (LDL), lipoproteínas de muy baja densidad (VLDL) urea. Hubo comportamiento cúbico para lipoproteínas de alta densidad (HDL) y creatinina. La inclusión de linaza (L. usitatissimum) en la dieta no presentó efecto hipercolesterolémico en estos animales.

Objetivo. Determinar la influencia de la castración bilateral de alpacas jóvenes sobre la composición centesimal y el contenido de colesterol en tejido muscular de cinco regiones anatómicas. Materiales y métodos. Se seleccionaron 20 animales machos, de 1.5 años de edad, de raza Huacaya, formándose dos grupos de 10 animales: experimental y control. Los del grupo experimental fueron sometidos a castración bilateral y los del grupo control permanecieron “enteros”. Después de seis meses, todos los animales fueron beneficiados y se tomaron muestras de tejido muscular de cinco regiones anatómicas: cuello, brazo, costillar, lomo y pierna. La humedad se determinó por desecación en estufa hasta peso constante, la grasa total por el método de Soxhlet, la proteína bruta por el método Kjeldahl, las cenizas por calcinación en mufla a 550˚C y el colesterol por el método colorimétrico previa extracción de grasas con cloroformo/metanol (2:1). Resultados. El contenido de grasa es superior en los castrados (2.28%) que en los enteros (1.82%) (P≤0.01) y varía entre las distintas regiones anatómicas (P≤0.05); la humedad es mayor en enteros (76.14%) que en castrados (75.45%) (P≤0.01), pero similar entre las distintas las regiones anatómicas (P>0.05); no hay diferencias en cuanto al contenido de proteínas, cenizas y colesterol (P>0.05), siendo el promedio de 20.39%, 1.13% y 55.56 mg/100 g, respectivamente. Conclusiones. Se evidenció que existe cierto efecto de la castración sobre la composición centesimal de la carne de alpaca de machos jóvenes al incrementar el contenido graso y disminuir la humedad.

El dengue es la arbovirosis con mayor incidencia a nivel mundial. Aproximadamente 100 millones de casos de dengue con signos de alarma y entre 250.000 y 500.000 casos de dengue grave, se registran anualmente. En Ecuador, en los últimos cuatro años se han registrado 83.472 casos de dengue. Estudios previos evidencian un incremento de los casos que cursan con disfunción hepática. El objetivo de este estudio fue analizar la asociación entre los niveles séricos de las enzimas aspartato aminotransferasa y alanino aminotransferasa y el perfil lipídico en pacientes con infección confirmada de Dengue. Se estudiaron 110 pacientes seleccionados sin distingo de edad, género o procedencia, cuyo diagnóstico fue confirmado virológica y serológicamente. Se incluyó un grupo control seronegativo al virus. En el perfil lipídico se evidenciaron diferencias significativas (p

Copyright of Gaceta Médica de Caracas is the property of Academia Nacional de Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Española de Cardiología (18855857) is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The trace element zinc is essential for the construction and function of cellular proteins. The current study aimed to estimate the improved cause of zinc on the changes resulting from high concentrations of cholesterol. In this experiment, thirty male rats aged 3-4 months were randomly divided into three groups of ten rats each. Control group: the animals did not receive any treatment, cholesterol group: the animals received cholesterol at a concentration of 400 mg/kg mixed with diet for 4 weeks, while in the zinc group: rats received cholesterol at a concentration of 400 mg/kg for 4 weeks, then zinc was given 20 mg/kg for another 4 weeks. The study period was 56 days, after its completion, hematological and biochemical parameters were studied, in addition to the histological examination of the liver. The results showed that cholesterol treatment alone led to significant negative changes in hematological, biochemical and histological indices. Whereas zinc administration to experimental rats resulted in clear positive effects in those parameters. We concluded that the cholesterol-damaged rats improved after receiving zinc. [ABSTRACT FROM AUTHOR]

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Atherosclerotic cardiovascular disease (ASCVD) remains the major cause of premature death and disability; effective cardiovascular (CV) risk prevention is fundamental. The World Heart Federation (WHF) Cholesterol Roadmap provides a framework for national policy development and aims to achieve ASCVD prevention. At the invitation of the WHF, a group of experts from the Portuguese Society of Cardiology (SPC), addressed the cholesterol burden at nationally and discussed possible strategies to include in a Portuguese cholesterol roadmap. The literature review showed that the cholesterol burden in Portugal is high and especially uncontrolled in those with the highest CV risk. An infographic scorecard was built to include in the WHF collection, for a clear idea about CV risk and cholesterol burden in Portugal, which would also be useful for health policy advocacy. The expert discussion and preventive strategies proposal followed the five pillars of the WHF document: awareness improvement; population-based approaches for CV risk and cholesterol; risk assessment/population screening; system-level approaches; surveillance of cholesterol and ASCVD outcomes. These strategies were debated by all the expert participants, with the goal of creating a national cholesterol roadmap to be used for advocacy and as a guide for CV prevention. Several key recommendations were outlined: include all stakeholders in a multidisciplinary national program; create a structured activities plan to increase awareness in the population; improve the quality of continuous CV health education; increase the interaction between different health professionals and non-health professionals; increment the referral of patients to cardiac rehabilitation; screen cholesterol levels in the general population, especially high-risk groups; promote patient self-care, engage with patients' associations; use specific social networks to spread information widely; create a national database of cholesterol levels with systematic registry of CV events; redefine strategies based on the evaluation of results; create and involve more patients' associations - invert the pyramid order. In conclusion, ASCVD and the cholesterol burden remain a strong global issue in Portugal, requiring the involvement of multiple stakeholders in prevention. The Portuguese cholesterol roadmap can provide some solutions to help urgently mitigate the problem. Population-based approaches to improve awareness and CV risk assessment and surveillance of cholesterol and ASCVD outcomes are key factors in this change. A call to action is clearly needed to fight hypercholesterolemia and ASCVD burden., (Copyright © 2024. Publicado por Elsevier España, S.L.U.)