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335 results on '"Cohen, Stacey A"'

2. SWOG S1820: A pilot randomized trial of the Altering Intake, Managing Bowel Symptoms Intervention in Survivors of Rectal Cancer

Author

Sun, Virginia, Guthrie, Katherine A, Crane, Tracy E, Arnold, Kathryn B, Colby, Sarah, Freylersythe, Sarah G, Braun‐Inglis, Christa, Topacio, Roxanne, Messick, Craig A, Carmichael, Joseph C, Muskovitz, Andrew A, Nashawaty, Mohammed, Bajaj, Madhuri, Cohen, Stacey A, Flaherty, Devin C, O’Rourke, Mark A, Jones, Lee, Krouse, Robert S, and Thomson, Cynthia A

Subjects
Health Services and Systems, Nursing, Health Sciences, Rare Diseases, Clinical Trials and Supportive Activities, Behavioral and Social Science, Colo-Rectal Cancer, Clinical Research, Cancer, Digestive Diseases, Health Disparities, Women's Health, Nutrition, Prevention, Management of diseases and conditions, 7.1 Individual care needs, Oral and gastrointestinal, Humans, Rectal Neoplasms, Middle Aged, Female, Male, Pilot Projects, Cancer Survivors, Quality of Life, Aged, Adult, bowel dysfunction, low anterior resection syndrome, quality of life, rectal cancer, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis, Public health
Abstract

BackgroundSurvivors of rectal cancer experience persistent bowel dysfunction after treatments. Dietary interventions may be an effective approach for symptom management and posttreatment diet quality. SWOG S1820 was a pilot randomized trial of the Altering Intake, Managing Symptoms in Rectal Cancer (AIMS-RC) intervention for bowel dysfunction in survivors of rectal cancer.MethodsNinety-three posttreatment survivors were randomized to the AIMS-RC group (N = 47) or the Healthy Living Education attention control group (N = 46) after informed consent and completion of a prerandomization run-in. Outcome measures were completed at baseline and at 18 and 26 weeks postrandomization. The primary end point was total bowel function score, and exploratory end points included low anterior resection syndrome (LARS) score, quality of life, dietary quality, motivation, self-efficacy, and positive/negative affect.ResultsMost participants were White and college educated, with a mean age of 55.2 years and median time since surgery of 13.1 months. There were no statistically significant differences in total bowel function score by group, with the AIMS-RC group demonstrating statistically significant improvements in the exploratory end points of LARS (p = .01) and the frequency subscale of the bowel function index (p = .03). The AIMS-RC group reported significantly higher acceptability of the study.ConclusionsSWOG S1820 did not provide evidence of benefit from the AIMS-RC intervention relative to the attention control. Select secondary end points did demonstrate improvements. The study was highly feasible and acceptable for participants in the National Cancer Institute Community Oncology Research Program. Findings provide strong support for further refinement and effectiveness testing of the AIMS-RC intervention.

Published
2024

3. Baseline characteristics and recruitment for SWOG S1820: altering intake, managing bowel symptoms in survivors of rectal cancer (AIMS-RC)

Author

Sun, Virginia, Thomson, Cynthia A, Crane, Tracy E, Arnold, Kathryn B, Guthrie, Katherine A, Freylersythe, Sarah G, Braun-Inglis, Christa, Jones, Lee, Carmichael, Joseph C, Messick, Craig, Flaherty, Devin, Ambrale, Samir, Cohen, Stacey A, and Krouse, Robert S

Subjects
Health Services and Systems, Nursing, Health Sciences, Behavioral and Social Science, Clinical Trials and Supportive Activities, Cancer, Colo-Rectal Cancer, Prevention, Clinical Research, Nutrition, Digestive Diseases, Rare Diseases, Oral and gastrointestinal, Good Health and Well Being, Humans, Rectal Neoplasms, Male, Female, Middle Aged, Cancer Survivors, Aged, Quality of Life, Adult, Patient Selection, Self Efficacy, Feasibility Studies, Bowel dysfunction, Diet modification, Intervention, Quality of life, Self-management, Medical and Health Sciences, Psychology and Cognitive Sciences, Oncology & Carcinogenesis, Biomedical and clinical sciences, Health sciences, Psychology
Abstract

PurposeMany survivors of rectal cancer experience persistent bowel dysfunction. There are few evidence-based symptom management interventions to improve bowel control. The purpose of this study is to describe recruitment and pre-randomization baseline sociodemographic, health status, and clinical characteristics for SWOG S1820, a trial of the Altering Intake, Managing Symptoms in Rectal Cancer (AIMS-RC) intervention.MethodsSWOG S1820 aimed to determine the preliminary efficacy, feasibility, and acceptability of AIMS-RC, a symptom management intervention for bowel health, comparing intervention to attention control. Survivors with a history of cancers of the rectosigmoid colon or rectum, within 6-24 months of primary treatment completion, with a post-surgical permanent ostomy or anastomosis, and over 18 years of age were enrolled. Outcomes included total bowel function, low anterior resection syndrome, quality of life, motivation for managing bowel health, self-efficacy for managing symptoms, positive and negative affect, and study feasibility and acceptability.ResultsThe trial completed accrual over a 29-month period and enrolled 117 participants from 34 institutions across 17 states and one US Pacific territory. At baseline, most enrolled participants reported self-imposed diet adjustments after surgery, persistent dietary intolerances, and bowel discomfort post-treatment, with high levels of constipation and diarrhea (grades 1-4).ConclusionsSWOG S1820 was able to recruit, in a timely manner, a study cohort that is demographically representative of US survivors of rectal cancer. Baseline characteristics illustrate the connection between diet/eating and bowel symptoms post-treatment, with many participants reporting diet adjustments and persistent inability to be comfortable with dietary intake.ClinicaltrialsGov registration date12/19/2019.ClinicaltrialsGov identifierNCT#04205955.

Published
2024

8. Functional quality of life among newly diagnosed young adult colorectal cancer survivors compared to older adults: results from the ColoCare Study

Author

Oswald, Laura B., Bloomer, Amanda, Li, Xiaoyin, Jean-Baptiste, Esther, Trujillo, Gillian, Felder, Seth, Small, Brent J., Ose, Jennifer, Hardikar, Sheetal, Strehli, Ildiko, Huang, Lyen C., Mooney, Kathi, Mutch, Matthew G., Chao, Dante, Cohen, Stacey A., Karchi, Meghana, Wood, Elizabeth H., Damerell, Victoria, Loroña, Nicole C., Gong, Jun, Toriola, Adetunji T., Li, Christopher I., Shibata, David, Schneider, Martin, Gigic, Biljana, Figueiredo, Jane C., Jim, Heather S. L., Ulrich, Cornelia M., and Siegel, Erin M.

Published
2024
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9. Clinical signatures of genetic epilepsies precede diagnosis in electronic medical records of 32,000 individuals

Author

Galer, Peter D., Parthasarathy, Shridhar, Xian, Julie, McKee, Jillian L., Ruggiero, Sarah M., Ganesan, Shiva, Kaufman, Michael C., Cohen, Stacey R., Haag, Scott, Chen, Chen, Ojemann, William K.S., Kim, Dan, Wilmarth, Olivia, Vaidiswaran, Priya, Sederman, Casey, Ellis, Colin A., Gonzalez, Alexander K., Boßelmann, Christian M., Lal, Dennis, Sederman, Rob, Lewis-Smith, David, Litt, Brian, and Helbig, Ingo

Published
2024
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10. Associations of combined physical activity and body mass index groups with colorectal cancer survival outcomes

Author

Himbert, Caroline, Ose, Jennifer, Gigic, Biljana, Viskochil, Richard, Santuci, Kelly, Lin, Tengda, Ashworth, Anjelica, Cohan, Jessica N., Scaife, Courtney L., Jedrzkiewicz, Jolanta, Damerell, Victoria, Atkins, Katelyn M., Gong, Jun, Mutch, Matthew G., Bernadt, Corey, Felder, Seth, Sanchez, Julian, Cohen, Stacey A., Krane, Mukta K., Hinkle, Nathan, Wood, Elizabeth, Peoples, Anita R., Figueiredo, Jane C., Toriola, Adetunji T., Siegel, Erin M., Li, Christopher I., Shibata, David, Boucher, Kenneth, Round, June L., Ulrich, Alexis B., Schneider, Martin, Huang, Lyen C., Hardikar, Sheetal, and Ulrich, Cornelia M.

Published
2023
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12. Biallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections

Author

Borras, Silvia, Clark, Caroline, Dean, John, Miedzybrodzka, Zosia, Ross, Alison, Tennant, Stephen, Dabir, Tabib, Donnelly, Deirdre, Humphreys, Mervyn, Magee, Alex, McConnell, Vivienne, McKee, Shane, McNerlan, Susan, Morrison, Patrick J., Rea, Gillian, Stewart, Fiona, Cole, Trevor, Cooper, Nicola, Cooper-Charles, Lisa, Cox, Helen, Islam, Lily, Jarvis, Joanna, Keelagher, Rebecca, Lim, Derek, McMullan, Dominic, Morton, Jenny, Naik, Swati, O’Driscoll, Mary, Ong, Kai-Ren, Osio, Deborah, Ragge, Nicola, Turton, Sarah, Vogt, Julie, Williams, Denise, Bodek, Simon, Donaldson, Alan, Hills, Alison, Low, Karen, Newbury-Ecob, Ruth, Norman, Andrew M., Roberts, Eileen, Scurr, Ingrid, Smithson, Sarah, Tooley, Madeleine, Abbs, Steve, Armstrong, Ruth, Dunn, Carolyn, Holden, Simon, Park, Soo-Mi, Paterson, Joan, Raymond, Lucy, Reid, Evan, Sandford, Richard, Simonic, Ingrid, Tischkowitz, Marc, Woods, Geoff, Bradley, Lisa, Comerford, Joanne, Green, Andrew, Lynch, Sally, McQuaid, Shirley, Mullaney, Brendan, Berg, Jonathan, Goudie, David, Mavrak, Eleni, McLean, Joanne, McWilliam, Catherine, Reavey, Eleanor, Azam, Tara, Cleary, Elaine, Jackson, Andrew, Lam, Wayne, Lampe, Anne, Moore, David, Porteous, Mary, Baple, Emma, Baptista, Júlia, Brewer, Carole, Castle, Bruce, Kivuva, Emma, Owens, Martina, Rankin, Julia, Shaw-Smith, Charles, Turner, Claire, Turnpenny, Peter, Tysoe, Carolyn, Bradley, Therese, Davidson, Rosemarie, Gardiner, Carol, Joss, Shelagh, Kinning, Esther, Longman, Cheryl, McGowan, Ruth, Murday, Victoria, Pilz, Daniela, Tobias, Edward, Whiteford, Margo, Williams, Nicola, Barnicoat, Angela, Clement, Emma, Faravelli, Francesca, Hurst, Jane, Jenkins, Lucy, Jones, Wendy, Ajith Kumar, V.K., Lees, Melissa, Loughlin, Sam, Male, Alison, Morrogh, Deborah, Rosser, Elisabeth, Scott, Richard, Wilson, Louise, Beleza, Ana, Deshpande, Charu, Flinter, Frances, Holder, Muriel, Irving, Melita, Izatt, Louise, Josifova, Dragana, Mohammed, Shehla, Molenda, Aneta, Robert, Leema, Roworth, Wendy, Ruddy, Deborah, Ryten, Mina, Yau, Shu, Bennett, Christopher, Blyth, Moira, Campbell, Jennifer, Coates, Andrea, Dobbie, Angus, Hewitt, Sarah, Hobson, Emma, Jackson, Eilidh, Jewell, Rosalyn, Kraus, Alison, Prescott, Katrina, Sheridan, Eamonn, Thomson, Jenny, Bradshaw, Kirsty, Dixit, Abhijit, Eason, Jacqueline, Haines, Rebecca, Harrison, Rachel, Mutch, Stacey, Sarkar, Ajoy, Searle, Claire, Shannon, Nora, Sharif, Abid, Suri, Mohnish, Vasudevan, Pradeep, Canham, Natalie, Ellis, Ian, Greenhalgh, Lynn, Howard, Emma, Stinton, Victoria, Swale, Andrew, Weber, Astrid, Banka, Siddharth, Breen, Catherine, Briggs, Tracy, Burkitt-Wright, Emma, Chandler, Kate, Clayton-Smith, Jill, Donnai, Dian, Douzgou, Sofia, Gaunt, Lorraine, Jones, Elizabeth, Kerr, Bronwyn, Langley, Claire, Metcalfe, Kay, Smith, Audrey, Wright, Ronnie, Bourn, David, Burn, John, Fisher, Richard, Hellens, Steve, Henderson, Alex, Montgomery, Tara, Splitt, Miranda, Straub, Volker, Wright, Michael, Zwolinski, Simon, Allen, Zoe, Bernhard, Birgitta, Brady, Angela, Brooks, Claire, Busby, Louise, Clowes, Virginia, Ghali, Neeti, Holder, Susan, Ibitoye, Rita, Wakeling, Emma, Blair, Edward, Carmichael, Jenny, Cilliers, Deirdre, Clasper, Susan, Gibbons, Richard, Kini, Usha, Lester, Tracy, Nemeth, Andrea, Poulton, Joanna, Price, Sue, Shears, Debbie, Stewart, Helen, Wilkie, Andrew, Albaba, Shadi, Baker, Duncan, Balasubramanian, Meena, Johnson, Diana, Parker, Michael, Quarrell, Oliver, Stewart, Alison, Willoughby, Josh, Crosby, Charlene, Elmslie, Frances, Homfray, Tessa, Jin, Huilin, Lahiri, Nayana, Mansour, Sahar, Marks, Karen, McEntagart, Meriel, Saggar, Anand, Tatton-Brown, Kate, Butler, Rachel, Clarke, Angus, Corrin, Sian, Fry, Andrew, Kamath, Arveen, McCann, Emma, Mugalaasi, Hood, Pottinger, Caroline, Procter, Annie, Sampson, Julian, Sansbury, Francis, Varghese, Vinod, Baralle, Diana, Callaway, Alison, Cassidy, Emma J., Daniels, Stacey, Douglas, Andrew, Foulds, Nicola, Hunt, David, Kharbanda, Mira, Lachlan, Katherine, Mercer, Catherine, Side, Lucy, Temple, I. Karen, Wellesley, Diana, Ambrose, J.C., Arumugam, P., Baple, E.L., Bleda, M., Boardman-Pretty, F., Boissiere, J.M., Boustred, C.R., Caulfield, M.J., Chan, G.C., Craig, C.E.H., Daugherty, L.C., de Burca, A., Devereau, A., Elgar, G., Foulger, R.E., Fowler, T., FurióTarí, P., Hackett, J.M., Halai, D., Hamblin, A., Henderson, S., Holman, J.E., Hubbard, T.J.P., Ibáñez, K., Jackson, R., Jones, L.J., Kasperaviciute, D., Kayikci, M., Lahnstein, L., Lawson, K., Leigh, S.E.A., Leong, I.U.S., Lopez, F.J., MaleadyCrowe, F., Mason, J., McDonagh, E.M., Moutsianas, L., Mueller, M., Murugaesu, N., Need, A.C., Odhams, C.A., Patch, C., Perez-Gil, D., Polychronopoulos, D., Pullinger, J., Rahim, T., Rendon, A., Riesgo-Ferreiro, P., Rogers, T., Ryten, M., Savage, K., Sawant, K., Scott, R.H., Siddiq, A., Sieghart, A., Smedley, D., Smith, K.R., Sosinsky, A., Spooner, W., Stevens, H.E., Stuckey, A., Sultana, R., Thomas, E.R.A., Thompson, S.R., Tucci, A., Walsh, E., Watters, S.A., Welland, M.J., Williams, E., Witkowska, K., Acosta, Maria T., Adam, Margaret, Adams, David R., Agrawal, Pankaj B., Alejandro, Mercedes E., Alvey, Justin, Amendola, Laura, Andrews, Ashley, Ashley, Euan A., Azamian, Mahshid S., Bacino, Carlos A., Bademci, Guney, Baker, Eva, Balasubramanyam, Ashok, Baldridge, Dustin, Bale, Jim, Bamshad, Michael, Barbouth, Deborah, Bayrak-Toydemir, Pinar, Beck, Anita, Beggs, Alan H., Behrens, Edward, Bejerano, Gill, Bennet, Jimmy, Berg-Rood, Beverly, Bernstein, Jonathan A., Berry, Gerard T., Bican, Anna, Bivona, Stephanie, Blue, Elizabeth, Bohnsack, John, Bonnenmann, Carsten, Bonner, Devon, Botto, Lorenzo, Boyd, Brenna, Briere, Lauren C., Brokamp, Elly, Brown, Gabrielle, Burke, Elizabeth A., Burrage, Lindsay C., Butte, Manish J., Byers, Peter, Byrd, William E., Carey, John, Carrasquillo, Olveen, Peter Chang, Ta Chen, Chanprasert, Sirisak, Chao, Hsiao-Tuan, Clark, Gary D., Coakley, Terra R., Cobban, Laurel A., Cogan, Joy D., Coggins, Matthew, Cole, F. Sessions, Colley, Heather A., Cooper, Cynthia M., Craigen, William J., Crouse, Andrew B., Cunningham, Michael, D'Souza, Precilla, Dai, Hongzheng, Dasari, Surendra, Davids, Mariska, Dayal, Jyoti G., Deardorff, Matthew, Dell'Angelica, Esteban C., Dhar, Shweta U., Dipple, Katrina, Doherty, Daniel, Dorrani, Naghmeh, Douine, Emilie D., Draper, David D., Duncan, Laura, Earl, Dawn, Eckstein, David J., Emrick, Lisa T., Eng, Christine M., Esteves, Cecilia, Estwick, Tyra, Falk, Marni, Fernandez, Liliana, Ferreira, Carlos, Fieg, Elizabeth L., Findley, Laurie C., Fisher, Paul G., Fogel, Brent L., Forghani, Irman, Fresard, Laure, Gahl, William A., Glass, Ian, Godfrey, Rena A., Golden-Grant, Katie, Goldman, Alica M., Goldstein, David B., Grajewski, Alana, Groden, Catherine A., Gropman, Andrea L., Gutierrez, Irma, Hahn, Sihoun, Hamid, Rizwan, Hanchard, Neil A., Hassey, Kelly, Hayes, Nichole, High, Frances, Hing, Anne, Hisama, Fuki M., Holm, Ingrid A., Hom, Jason, Horike-Pyne, Martha, Huang, Alden, Huang, Yong, Isasi, Rosario, Jamal, Fariha, Jarvik, Gail P., Jarvik, Jeffrey, Jayadev, Suman, Johnston, Jean M., Karaviti, Lefkothea, Kelley, Emily G., Kennedy, Jennifer, Kiley, Dana, Kohane, Isaac S., Kohler, Jennefer N., Krakow, Deborah, Krasnewich, Donna M., Kravets, Elijah, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lalani, Seema R., Lam, Byron, Lam, Christina, Lanpher, Brendan C., Lanza, Ian R., Lau, C. Christopher, LeBlanc, Kimberly, Lee, Brendan H., Lee, Hane, Levitt, Roy, Lewis, Richard A., Lincoln, Sharyn A., Liu, Pengfei, Liu, Xue Zhong, Longo, Nicola, Loo, Sandra K., Loscalzo, Joseph, Maas, Richard L., Macnamara, Ellen F., MacRae, Calum A., Maduro, Valerie V., Majcherska, Marta M., Mak, Bryan, Malicdan, May Christine V., Mamounas, Laura A., Manolio, Teri A., Mao, Rong, Maravilla, Kenneth, Markello, Thomas C., Marom, Ronit, Marth, Gabor, Martin, Beth A., Martin, Martin G., Martínez-Agosto, Julian A., Marwaha, Shruti, McCauley, Jacob, McCormack, Colleen E., McCray, Alexa T., McGee, Elisabeth, Mefford, Heather, Merritt, J. Lawrence, Might, Matthew, Mirzaa, Ghayda, Morava, Eva, Moretti, Paolo M., Morimoto, Marie, Mulvihill, John J., Murdock, David R., Nakano-Okuno, Mariko, Nath, Avi, Nelson, Stan F., Newman, John H., Nicholas, Sarah K., Nickerson, Deborah, Nieves-Rodriguez, Shirley, Novacic, Donna, Oglesbee, Devin, Orengo, James P., Pace, Laura, Pak, Stephen, Pallais, J. Carl, Papp, Jeanette C., Parker, Neil H., Phillips, John A., Posey, Jennifer E., Potocki, Lorraine, Pusey, Barbara N., Quinlan, Aaron, Raskind, Wendy, Raja, Archana N., Rao, Deepak A., Renteria, Genecee, Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Rosenfeld, Jill A., Rosenwasser, Natalie, Ruzhnikov, Maura, Sacco, Ralph, Sampson, Jacinda B., Samson, Susan L., Saporta, Mario, Scott, C. Ron, Schaechter, Judy, Schedl, Timothy, Scott, Daryl A., Sharma, Prashant, Shin, Jimann, Signer, Rebecca, Sillari, Catherine H., Silverman, Edwin K., Sinsheimer, Janet S., Sisco, Kathy, Smith, Edward C., Smith, Kevin S., Solem, Emily, Solnica-Krezel, Lilianna, Stoler, Joan M., Stong, Nicholas, Sullivan, Jennifer A., Sun, Angela, Sutton, Shirley, Sweetser, David A., Sybert, Virginia, Tabor, Holly K., Tamburro, Cecelia P., Tekin, Mustafa, Telischi, Fred, Thorson, Willa, Tifft, Cynthia J., Toro, Camilo, Tran, Alyssa A., Tucker, Brianna M., Urv, Tiina K., Vanderver, Adeline, Velinder, Matt, Viskochil, Dave, Vogel, Tiphanie P., Wahl, Colleen E., Wallace, Stephanie, Walley, Nicole M., Walsh, Chris A., Walker, Melissa, Wambach, Jennifer, Wan, Jijun, Wang, Lee-Kai, Wangler, Michael F., Ward, Patricia A., Wegner, Daniel, Wener, Mark, Wenger, Tara, Perry, Katherine Wesseling, Westerfield, Monte, Wheeler, Matthew T., Whitlock, Jordan, Wolfe, Lynne A., Woods, Jeremy D., Yamamoto, Shinya, Yang, John, Yu, Guoyun, Zastrow, Diane B., Zhao, Chunli, Zuchner, Stephan, Jeffries, Lauren, Mis, Emily K., McWalter, Kirsty, Donkervoort, Sandra, Brodsky, Nina N., Carpier, Jean-Marie, Ji, Weizhen, Ionita, Cristian, Roy, Bhaskar, Morrow, Jon S., Darbinyan, Armine, Iyer, Krishna, Aul, Ritu B., Chao, Katherine R., Cobbold, Laura, Cohen, Stacey, Custodio, Helena M., Drummond-Borg, Margaret, Finanger, Erika, Hainline, Bryan E., Helbig, Ingo, Hewson, Stacy, Hu, Ying, Jackson, Adam, Konstantino, Monica, Leach, Meganne E., McCormick, David, Nelson, Stanley, Nguyen, Joanne, Nugent, Kimberly, Ortega, Lucy, Goodkin, Howard P., Roeder, Elizabeth, Roy, Sani, Sapp, Katie, Saade, Dimah, Sisodiya, Sanjay M., Stals, Karen, Towner, Shelley, Wilson, William, Khokha, Mustafa K., Bönnemann, Carsten G., Lucas, Carrie L., and Lakhani, Saquib A.

Published
2024
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13. A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3

Author

Acosta, Maria T., Adam, Margaret, Adams, David R., Alvarez, Raquel L., Alvey, Justin, Amendola, Laura, Andrews, Ashley, Ashley, Euan A., Bacino, Carlos A., Bademci, Guney, Balasubramanyam, Ashok, Baldridge, Dustin, Bale, Jim, Bamshad, Michael, Barbouth, Deborah, Bayrak-Toydemir, Pinar, Beck, Anita, Beggs, Alan H., Behrens, Edward, Bejerano, Gill, Bellen, Hugo J., Bennett, Jimmy, Berg-Rood, Beverly, Bernstein, Jonathan A., Berry, Gerard T., Bican, Anna, Bivona, Stephanie, Blue, Elizabeth, Bohnsack, John, Bonner, Devon, Botto, Lorenzo, Boyd, Brenna, Briere, Lauren C., Brown, Gabrielle, Burke, Elizabeth A., Burrage, Lindsay C., Butte, Manish J., Byers, Peter, Byrd, William E., Carey, John, Carrasquillo, Olveen, Cassini, Thomas, Chang, Ta Chen Peter, Chanprasert, Sirisak, Chao, Hsiao-Tuan, Chinn, Ivan, Clark, Gary D., Coakley, Terra R., Cobban, Laurel A., Cogan, Joy D., Coggins, Matthew, Cole, F. Sessions, Colley, Heather A., Cope, Heidi, Corona, Rosario, Craigen, William J., Crouse, Andrew B., Cunningham, Michael, D’Souza, Precilla, Dai, Hongzheng, Dasari, Surendra, Davis, Joie, Dayal, Jyoti G., Dell'Angelica, Esteban C., Dipple, Katrina, Doherty, Daniel, Dorrani, Naghmeh, Doss, Argenia L., Douine, Emilie D., Earl, Dawn, Eckstein, David J., Emrick, Lisa T., Eng, Christine M., Falk, Marni, Fieg, Elizabeth L., Fisher, Paul G., Fogel, Brent L., Forghani, Irman, Gahl, William A., Glass, Ian, Gochuico, Bernadette, Goddard, Page C., Godfrey, Rena A., Golden-Grant, Katie, Grajewski, Alana, Hadley, Don, Hahn, Sihoun, Halley, Meghan C., Hamid, Rizwan, Hassey, Kelly, Hayes, Nichole, High, Frances, Hing, Anne, Hisama, Fuki M., Holm, Ingrid A., Hom, Jason, Horike-Pyne, Martha, Huang, Alden, Hutchison, Sarah, Introne, Wendy, Isasi, Rosario, Izumi, Kosuke, Jamal, Fariha, Jarvik, Gail P., Jarvik, Jeffrey, Jayadev, Suman, Jean-Marie, Orpa, Jobanputra, Vaidehi, Karaviti, Lefkothea, Ketkar, Shamika, Kiley, Dana, Kilich, Gonench, Kobren, Shilpa N., Kohane, Isaac S., Kohler, Jennefer N., Korrick, Susan, Kozuira, Mary, Krakow, Deborah, Krasnewich, Donna M., Kravets, Elijah, Lalani, Seema R., Lam, Byron, Lam, Christina, Lanpher, Brendan C., Lanza, Ian R., LeBlanc, Kimberly, Lee, Brendan H., Levitt, Roy, Lewis, Richard A., Liu, Pengfei, Liu, Xue Zhong, Longo, Nicola, Loo, Sandra K., Loscalzo, Joseph, Maas, Richard L., Macnamara, Ellen F., MacRae, Calum A., Maduro, Valerie V., Maghiro, Audrey Stephannie, Mahoney, Rachel, Malicdan, May Christine V., Mamounas, Laura A., Manolio, Teri A., Mao, Rong, Maravilla, Kenneth, Marom, Ronit, Marth, Gabor, Martin, Beth A., Martin, Martin G., Martínez-Agosto, Julian A., Marwaha, Shruti, McCauley, Jacob, McConkie-Rosell, Allyn, McCray, Alexa T., McGee, Elisabeth, Mefford, Heather, Merritt, J. Lawrence, Might, Matthew, Mirzaa, Ghayda, Morava, Eva, Moretti, Paolo, Mulvihill, John, Nakano-Okuno, Mariko, Nelson, Stanley F., Newman, John H., Nicholas, Sarah K., Nickerson, Deborah, Nieves-Rodriguez, Shirley, Novacic, Donna, Oglesbee, Devin, Orengo, James P., Pace, Laura, Pak, Stephen, Pallais, J. Carl, Palmer, Christina G.S., Papp, Jeanette C., Parker, Neil H., Phillips III, John A., Posey, Jennifer E., Potocki, Lorraine, Pusey Swerdzewski, Barbara N., Quinlan, Aaron, Rao, Deepak A., Raper, Anna, Raskind, Wendy, Renteria, Genecee, Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Rosenfeld, Jill A., Rosenwasser, Natalie, Rossignol, Francis, Ruzhnikov, Maura, Sacco, Ralph, Sampson, Jacinda B., Saporta, Mario, Schaechter, Judy, Schedl, Timothy, Schoch, Kelly, Scott, Daryl A., Scott, C. Ron, Seto, Elaine, Shashi, Vandana, Shin, Jimann, Silverman, Edwin K., Sinsheimer, Janet S., Sisco, Kathy, Smith, Edward C., Smith, Kevin S., Solnica-Krezel, Lilianna, Solomon, Ben, Spillmann, Rebecca C., Stoler, Joan M., Sullivan, Kathleen, Sullivan, Jennifer A., Sun, Angela, Sutton, Shirley, Sweetser, David A., Sybert, Virginia, Tabor, Holly K., Tan, Queenie K.-G., Tan, Amelia L.M., Tarakad, Arjun, Tekin, Mustafa, Telischi, Fred, Thorson, Willa, Tifft, Cynthia J., Toro, Camilo, Tran, Alyssa A., Ungar, Rachel A., Urv, Tiina K., Vanderver, Adeline, Velinder, Matt, Viskochil, Dave, Vogel, Tiphanie P., Wahl, Colleen E., Walker, Melissa, Wallace, Stephanie, Walley, Nicole M., Wambach, Jennifer, Wan, Jijun, Wang, Lee-kai, Wangler, Michael F., Ward, Patricia A., Wegner, Daniel, Weisz Hubshman, Monika, Wener, Mark, Wenger, Tara, Westerfield, Monte, Wheeler, Matthew T., Whitlock, Jordan, Wolfe, Lynne A., Worley, Kim, Xiao, Changrui, Yamamoto, Shinya, Yang, John, Zhang, Zhe, Zuchner, Stephan, Paul, Maimuna S., Michener, Sydney L., Pan, Hongling, Chan, Hiuling, Pfliger, Jessica M., Lerma, Vanesa C., Tran, Alyssa, Longley, Megan A., Weisz-Hubshman, Monika, Bekheirnia, Mir Reza, Bekheirnia, Nasim, Massingham, Lauren, Zech, Michael, Wagner, Matias, Engels, Hartmut, Cremer, Kirsten, Mangold, Elisabeth, Peters, Sophia, Trautmann, Jessica, Perne, Claudia, Mester, Jessica L., Guillen Sacoto, Maria J., Person, Richard, McDonnell, Pamela P., Cohen, Stacey R., Lusk, Laina, Cohen, Ana S.A., Le Pichon, Jean-Baptiste, Pastinen, Tomi, Zhou, Dihong, Engleman, Kendra, Racine, Caroline, Faivre, Laurence, Moutton, Sébastien, Denommé-Pichon, Anne-Sophie, Koh, Hyun Yong, Poduri, Annapurna, Bolton, Jeffrey, Knopp, Cordula, Julia Suh, Dong Sun, Maier, Andrea, Toosi, Mehran Beiraghi, Karimiani, Ehsan Ghayoor, Maroofian, Reza, Schaefer, Gerald Bradley, Ramakumaran, Vijayalakshmi, Vasudevan, Pradeep, Banos-Pinero, Benito, Pagnamenta, Alistair T., Prasad, Chitra, Osmond, Matthew, Schuhmann, Sarah, Vasileiou, Georgia, Russ-Hall, Sophie, Scheffer, Ingrid E., and Carvill, Gemma L.

Published
2024
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14. Clinical Characteristics and Outcomes of Colorectal Cancer in the ColoCare Study: Differences by Age of Onset

Author

Himbert, Caroline, Figueiredo, Jane C, Shibata, David, Ose, Jennifer, Lin, Tengda, Huang, Lyen C, Peoples, Anita R, Scaife, Courtney L, Pickron, Bartley, Lambert, Laura, Cohan, Jessica N, Bronner, Mary, Felder, Seth, Sanchez, Julian, Dessureault, Sophie, Coppola, Domenico, Hoffman, David M, Nasseri, Yosef F, Decker, Robert W, Zaghiyan, Karen, Murrell, Zuri A, Hendifar, Andrew, Gong, Jun, Firoozmand, Eiman, Gangi, Alexandra, Moore, Beth A, Cologne, Kyle G, El-Masry, Maryliza S, Hinkle, Nathan, Monroe, Justin, Mutch, Matthew, Bernadt, Cory, Chatterjee, Deyali, Sinanan, Mika, Cohen, Stacey A, Wallin, Ulrike, Grady, William M, Lampe, Paul D, Reddi, Deepti, Krane, Mukta, Fichera, Alessandro, Moonka, Ravi, Herpel, Esther, Schirmacher, Peter, Kloor, Matthias, von Knebel-Doeberitz, Magnus, Nattenmueller, Johanna, Kauczor, Hans-Ulrich, Swanson, Eric, Jedrzkiewicz, Jolanta, Schmit, Stephanie L, Gigic, Biljana, Ulrich, Alexis B, Toriola, Adetunji T, Siegel, Erin M, Li, Christopher I, Ulrich, Cornelia M, and Hardikar, Sheetal

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Digestive Diseases, Colo-Rectal Cancer, Clinical Research, cohort, colorectal cancer, early onset, epidemiology, Oncology and carcinogenesis
Abstract

Early-onset colorectal cancer has been on the rise in Western populations. Here, we compare patient characteristics between those with early- (

Published
2021

15. Use of acupuncture with acupressure in addition to standard-of-care cryotherapy to decrease chemotherapy-associated neuropathy in patients with gastrointestinal malignancies receiving oxaliplatin-based chemotherapy: Study protocol for a randomized, controlled pilot and feasibility study

Author

Cohen, Stacey A., Veleber, Susan, Siman, Jonathan, Guthrie, Katherine A., McMillen, Kerry, Heit, Madilyn, Wadhera, Sonia, Daniels, Jonathan, Hansen, Kjell, Jacoby, Madeline, Taromina, Katherine, Chin, Samantha, Romeo, Melissa, Langley, Blake O., Coveler, Andrew L., Hannan, Lindsay M., King, Gentry, Purcell, Tom, Safyan, Rachael A., Shankaran, Veena, Zhen, David B., Chiorean, E. Gabriela, and Greenlee, Heather

Published
2023
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16. Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology

Author

Benson, Al B., primary, Venook, Alan P., additional, Adam, Mohamed, additional, Chang, George, additional, Chen, Yi-Jen, additional, Ciombor, Kristen K., additional, Cohen, Stacey A., additional, Cooper, Harry S., additional, Deming, Dustin, additional, Garrido-Laguna, Ignacio, additional, Grem, Jean L., additional, Haste, Paul, additional, Hecht, J. Randolph, additional, Hoffe, Sarah, additional, Hunt, Steven, additional, Hussan, Hisham, additional, Johung, Kimberly L., additional, Joseph, Nora, additional, Kirilcuk, Natalie, additional, Krishnamurthi, Smitha, additional, Malla, Midhun, additional, Maratt, Jennifer K., additional, Messersmith, Wells A., additional, Meyerhardt, Jeffrey, additional, Miller, Eric D., additional, Mulcahy, Mary F., additional, Nurkin, Steven, additional, Overman, Michael J., additional, Parikh, Aparna, additional, Patel, Hitendra, additional, Pedersen, Katrina, additional, Saltz, Leonard, additional, Schneider, Charles, additional, Shibata, David, additional, Shogan, Benjamin, additional, Skibber, John M., additional, Sofocleous, Constantinos T., additional, Tavakkoli, Anna, additional, Willett, Christopher G., additional, Wu, Christina, additional, Gurski, Lisa A., additional, Snedeker, Jenna, additional, and Jones, Frankie, additional

Published
2024
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17. NCCN Guidelines Insights: Colon Cancer, Version 2.2018.

Author

Benson, Al B, Venook, Alan P, Al-Hawary, Mahmoud M, Cederquist, Lynette, Chen, Yi-Jen, Ciombor, Kristen K, Cohen, Stacey, Cooper, Harry S, Deming, Dustin, Engstrom, Paul F, Garrido-Laguna, Ignacio, Grem, Jean L, Grothey, Axel, Hochster, Howard S, Hoffe, Sarah, Hunt, Steven, Kamel, Ahmed, Kirilcuk, Natalie, Krishnamurthi, Smitha, Messersmith, Wells A, Meyerhardt, Jeffrey, Miller, Eric D, Mulcahy, Mary F, Murphy, James D, Nurkin, Steven, Saltz, Leonard, Sharma, Sunil, Shibata, David, Skibber, John M, Sofocleous, Constantinos T, Stoffel, Elena M, Stotsky-Himelfarb, Eden, Willett, Christopher G, Wuthrick, Evan, Gregory, Kristina M, and Freedman-Cass, Deborah A

Subjects
Digestive Diseases, Cancer, Colo-Rectal Cancer, Good Health and Well Being, Colonic Neoplasms, Humans, Oncology & Carcinogenesis
Abstract

The NCCN Guidelines for Colon Cancer provide recommendations regarding diagnosis, pathologic staging, surgical management, perioperative treatment, surveillance, management of recurrent and metastatic disease, and survivorship. These NCCN Guidelines Insights summarize the NCCN Colon Cancer Panel discussions for the 2018 update of the guidelines regarding risk stratification and adjuvant treatment for patients with stage III colon cancer, and treatment of BRAF V600E mutation-positive metastatic colorectal cancer with regimens containing vemurafenib.

Published
2018

18. Optimizing clinical interpretability of functional evidence in epilepsy-related ion channel variants

Author

Parthasarathy, Shridhar, primary, Cohen, Stacey R, additional, Fitch, Eryn, additional, Vaidiswaran, Priya, additional, Ruggiero, Sarah M, additional, Lusk, Laina, additional, Chisari, Victoria, additional, Lewis-Smith, David, additional, Lauxmann, Stephan, additional, Bosselmann, Christian M, additional, Thompson, Christopher H, additional, Wengert, Eric R, additional, Hedrich, Ulrike, additional, Ganesan, Shiva, additional, Balagura, Ganna, additional, Krause, Roland, additional, Xian, Julie, additional, Galer, Peter D, additional, Pendziwiat, Manuela, additional, Perez-Palma, Eduardo, additional, Vihinen, Mauno, additional, Hart, Jennifer, additional, Landrum, Melissa J, additional, Lal, Dennis, additional, Cooper, Edward C, additional, Lerche, Holger, additional, Goldberg, Ethan M, additional, Brunklaus, Andreas, additional, Vanoye, Carlos G, additional, Schorge, Stephanie, additional, George, Alfred L, additional, and Helbig, Ingo, additional

Published
2024
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20. A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3

Author

Paul, Maimuna S., primary, Michener, Sydney L., additional, Pan, Hongling, additional, Chan, Hiuling, additional, Pfliger, Jessica M., additional, Rosenfeld, Jill A., additional, Lerma, Vanesa C., additional, Tran, Alyssa, additional, Longley, Megan A., additional, Lewis, Richard A., additional, Weisz-Hubshman, Monika, additional, Bekheirnia, Mir Reza, additional, Bekheirnia, Nasim, additional, Massingham, Lauren, additional, Zech, Michael, additional, Wagner, Matias, additional, Engels, Hartmut, additional, Cremer, Kirsten, additional, Mangold, Elisabeth, additional, Peters, Sophia, additional, Trautmann, Jessica, additional, Perne, Claudia, additional, Mester, Jessica L., additional, Guillen Sacoto, Maria J., additional, Person, Richard, additional, McDonnell, Pamela P., additional, Cohen, Stacey R., additional, Lusk, Laina, additional, Cohen, Ana S.A., additional, Le Pichon, Jean-Baptiste, additional, Pastinen, Tomi, additional, Zhou, Dihong, additional, Engleman, Kendra, additional, Racine, Caroline, additional, Faivre, Laurence, additional, Moutton, Sébastien, additional, Denommé-Pichon, Anne-Sophie, additional, Koh, Hyun Yong, additional, Poduri, Annapurna, additional, Bolton, Jeffrey, additional, Knopp, Cordula, additional, Julia Suh, Dong Sun, additional, Maier, Andrea, additional, Toosi, Mehran Beiraghi, additional, Karimiani, Ehsan Ghayoor, additional, Maroofian, Reza, additional, Schaefer, Gerald Bradley, additional, Ramakumaran, Vijayalakshmi, additional, Vasudevan, Pradeep, additional, Banos-Pinero, Benito, additional, Pagnamenta, Alistair T., additional, Prasad, Chitra, additional, Osmond, Matthew, additional, Schuhmann, Sarah, additional, Vasileiou, Georgia, additional, Russ-Hall, Sophie, additional, Scheffer, Ingrid E., additional, Carvill, Gemma L., additional, Mefford, Heather, additional, Bacino, Carlos A., additional, Lee, Brendan H., additional, and Chao (趙孝端), Hsiao-Tuan, additional

Published
2024
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21. Diagnostic Yield of Genetic Testing in Adults with Epilepsy (P7-1.010)

Author

Copeland, Juliette, primary, Baldwin, Aaron, additional, Raper, Anna, additional, Helbig, Katherine, additional, Sullivan, Katie Rose, additional, Ginn, Natalie, additional, Ruggiero, Sarah, additional, Lusk, Laina, additional, Cohen, Stacey, additional, Back, Amanda, additional, Fitzgerald, Mark, additional, Massey, Shavonne, additional, McDonnell, Pamela, additional, Goldberg, Ethan, additional, Helbig, Ingo, additional, and Ellis, Colin, additional

Published
2024
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22. Assessing the Clinical and Treatment Landscape of Genetic Epilepsies Through 3,760 Individuals (S24.007)

Author

Xian, Julie, primary, Kaufman, Michael, additional, Ruggiero, Sarah, additional, Ramos, Mark, additional, Gonzalez, Alexander, additional, Back, Amanda, additional, Bailey-medley, Lea, additional, Cohen, Stacey, additional, Cuddapah, Vishnu, additional, Ellis, Colin, additional, Ginn, Natalie, additional, Lewin, Naomi, additional, Lusk, Laina, additional, Marsh, Eric, additional, Massey, Shavonne, additional, Ortiz-Gonzalez, Xilma, additional, Mcdonnell, Pamela, additional, Sullivan, Katie Rose, additional, Taub, Katherine, additional, Tefft, Sarah, additional, Helbig, Katherine, additional, Goldberg, Ethan, additional, Helbig, Ingo, additional, and Fitzgerald, Mark, additional

Published
2024
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27. The Art of Hormone Replacement Therapy (HRT) in Menopause Management.

Author

Cameron, Courtney R., Cohen, Stacey, Sewell, Keri, and Lee, Meissane

Subjects
*BREAST tumor risk factors, *INFECTION risk factors, *THROMBOEMBOLISM risk factors, *PERIMENOPAUSE, *RISK assessment, *VEINS, *CARDIOVASCULAR diseases risk factors, *VAGINAL diseases, *ATROPHY, *HORMONE therapy, *DYSPAREUNIA, *STROKE, *DISEASE risk factors
Abstract

Hormone replacement therapy (HRT) is considered the gold standard for management of vasomotor and vaginal symptoms of menopause. Vasomotor symptoms of menopause may include hot flashes and diaphoresis that vary in intensity and duration. Other symptoms of menopause can include vaginal atrophy and dryness, leading to dyspareunia and increased risk of infection. These symptoms can be impactful on a woman's life and HRT has data to support its efficacy, however, HRT carries significant risks that are generally well known, including risk of stroke, cardiovascular disease, breast cancer, and venous thromboembolism. These risks were most well characterized by several landmark trials published in the early 2000s. There are several nuances to prescribing HRT that can make doing so complex. These include consideration of cyclic vs continuous administration and of tapering therapy. Additionally, estrogen is available in a variety of dosage forms including injections and transdermal formulations. However, for women with an intact uterus, estrogen will need to be combined with progestin or bazedoxifene (a selective estrogen receptor modulator – SERM), both once daily oral formulations, in order to minimize malignancy risk. Though product preference and considerations of dosing may vary depending on practitioner preference, this brief report aims to clarify some nuances to prescribing or recommending HRT. [ABSTRACT FROM AUTHOR]

Published
2024
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29. COVALENT-102: A phase 1/1b dose finding study of BMF-219, an oral covalent menin inhibitor, in adults with locally advanced, unresectable, or metastatic non-small cell lung cancer (NSCLC), pancreatic cancer (PDAC) and colorectal cancer (CRC) with activating KRAS mutations.

Author

Fountzilas, Christos, primary, Cohen, Stacey A., additional, Duvivier, Herbert Leon, additional, Hong, David S., additional, Pedersen, Katrina Sophia, additional, Pisick, Evan P., additional, Sommerhalder, David, additional, Cacovean, Alex, additional, Follit, Courtney, additional, Kowalczyk, Nicole, additional, Munneke, Brian, additional, Tong, Tracy, additional, Morris, Steve, additional, Butler, Thomas, additional, and Spira, Alexander I., additional

Published
2024
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30. Prognostic value of circulating tumor DNA (ctDNA) testing in patients (pts) with rectal cancer after neoadjuvant therapy (NAT) and surgery.

Author

Chakrabarti, Sakti, primary, Cohen, Stacey A., additional, Tin, Antony, additional, Dangl, Autumn, additional, Aushev, Vasily N., additional, Tejani, Mohamedtaki Abdulaziz, additional, Chandana, Sreenivasa R, additional, Malla, Midhun, additional, Landmann, Ron G., additional, Sharma, Vivek R., additional, Botta, Gregory P., additional, Nagarajan, Arun, additional, Azzi, Georges, additional, Cho, May Thet, additional, Dayyani, Farshid, additional, Hanna, Diana L., additional, Jurdi, Adham A, additional, Liu, Minetta C., additional, Dasari, Arvind, additional, and Kasi, Pashtoon Murtaza, additional

Published
2024
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31. Comparison of the disease presentation of early- vs. later-onset colorectal cancer within the prospective ColoCare study.

Author

Gottschalk, Zachary, primary, Redman, Mary Weber, additional, Baker, Kelsey K., additional, Ulrich, Cornelia M, additional, Siegel, Erin M., additional, Figueiredo, Jane C., additional, Shibata, David, additional, Toriola, Adetunji T., additional, Gigic, Biljana, additional, Ose, Jennifer, additional, Lin, Tengda, additional, Hardikar, Sheetal, additional, Li, Christopher I., additional, and Cohen, Stacey A., additional

Published
2024
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32. Genomic and immune landscape of biliary tract cancers with ARID1A, PBRM1, and BAP1 alterations.

Author

King, Gentry Teng, primary, Berg, Rachel, additional, Yilma, Binyam, additional, Stoppler, Melissa Conrad, additional, Hsieh, Ronan Wenhan, additional, Safyan, Rachael A, additional, Zhen, David Bing, additional, Coveler, Andrew L., additional, Cohen, Stacey A., additional, Shankaran, Veena, additional, Chiorean, E. Gabriela, additional, and Harris, William Proctor, additional

Published
2024
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33. Abstract A003: Preliminary safety results from a phase I study of autologous transgenic T cells expressing high affinity mesothelin-specific T cell receptor (TCR) (FH-TCR TMSLN) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDA)

Author

Chiorean, Elena G., primary, Chapuis, Aude, additional, Coveler, Andrew, additional, Yeung, Cecilia, additional, Gooley, Ted, additional, Zhen, David B., additional, King, Gentry, additional, Cohen, Stacey, additional, Hannan, Lindsay, additional, Safyan, Rachael, additional, Germani, Anthony, additional, Ra, Susan, additional, Casserd, Jennifer, additional, Schmitt, Tom, additional, and Greenberg, Philip, additional

Published
2024
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35. Prevalence and Correlates of Post-Diagnosis Alcohol Use among Cancer Survivors.

Author

Heffner, Jaimee L., Ton, Mimi, Jones, Salene M. W., Malen, Rachel C., Cohen, Stacey A., and Newcomb, Polly A.

Abstract

Background: Alcohol is a risk factor for cancer and may pose unique risks for cancer survivors. Population-based studies of confirmed cancer cases are needed to estimate the extent of drinking among cancer survivors and to understand which survivors are most at risk of alcohol-related health problems. Methods: Cancer survivors who resided in the Puget Sound Surveillance, Epidemiology, and End Results (SEER) region, were ages 21 to 74 years at diagnosis, and were 6 to 17 months post-diagnosis at the start of the recruitment period (April 2020-December 2020) were sent a survey that included demographics, substance use, mental health, and cancer-related items. Data from returned surveys (n = 1,488) were weighted to represent the characteristics of the Puget Sound SEER region. We estimated the prevalence of post-diagnosis alcohol use as well as demographic, behavioral, and clinical correlates of three levels of drinking: any drinking, drinking exceeding cancer prevention guidelines, and hazardous drinking. Results: The weighted prevalence of any drinking, drinking exceeding cancer prevention guidelines, and hazardous drinking was 71%, 46.2%, and 31.6%, respectively. Higher income and cannabis use were associated with increased odds of all three drinking levels. Lower physical health quality of life, having non-colorectal gastrointestinal cancer, and receiving chemotherapy within the last month were associated with decreased odds of all three drinking levels. Conclusions: The prevalence of any drinking and at-risk drinking was higher than in previous studies and differed based on sociodemographic, substance use, and cancer-related factors. Impact: Findings highlight the importance of identifying and addressing risky alcohol use in cancer care settings. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Biallelic CRELD1 variants cause a multisystem syndrome including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections.

Author

Jeffries, Lauren, primary, Mis, Emily K., additional, McWalter, Kirsty, additional, Donkervoort, Sandra, additional, Brodsky, Nina N., additional, Carpier, Jean-Marie, additional, Ji, Weizhen, additional, Ionita, Cristian, additional, Roy, Bhaskar, additional, Morrow, Jon S., additional, Darbinyan, Armine, additional, Iyer, Krishna, additional, Aul, Ritu B., additional, Banka, Siddharth, additional, Chao, Katherine R., additional, Cobbold, Laura, additional, Cohen, Stacey, additional, Custodio, Helena M., additional, Drummond-Borg, Margaret, additional, Elmslie, Frances, additional, Finanger, Erika, additional, Hainline, Bryan E., additional, Helbig, Ingo, additional, Hewson, Stacy, additional, Hu, Ying, additional, Jackson, Adam, additional, Josifova, Dragana, additional, Konstantino, Monica, additional, Leach, Meganne E., additional, Mak, Bryan, additional, McCormick, David, additional, McGee, Elisabeth, additional, Nelson, Stanley, additional, Nguyen, Joanne, additional, Nugent, Kimberly, additional, Ortega, Lucy, additional, Goodkin, Howard P., additional, Roeder, Elizabeth, additional, Roy, Sani, additional, Sapp, Katie, additional, Saade, Dimah, additional, Sisodiya, Sanjay M., additional, Stals, Karen, additional, Towner, Shelley, additional, Wilson, William, additional, Khokha, Mustafa K., additional, Bönnemann, Carsten G., additional, Lucas, Carrie L., additional, Lakhani, Saquib A., additional, Acosta, Maria T., additional, Adam, Margaret, additional, Adams, David R., additional, Agrawal, Pankaj B., additional, Alejandro, Mercedes E., additional, Alvey, Justin, additional, Amendola, Laura, additional, Andrews, Ashley, additional, Ashley, Euan A., additional, Azamian, Mahshid S., additional, Bacino, Carlos A., additional, Bademci, Guney, additional, Baker, Eva, additional, Balasubramanyam, Ashok, additional, Baldridge, Dustin, additional, Bale, Jim, additional, Bamshad, Michael, additional, Barbouth, Deborah, additional, Bayrak-Toydemir, Pinar, additional, Beck, Anita, additional, Beggs, Alan H., additional, Behrens, Edward, additional, Bejerano, Gill, additional, Bennet, Jimmy, additional, Berg-Rood, Beverly, additional, Bernstein, Jonathan A., additional, Berry, Gerard T., additional, Bican, Anna, additional, Bivona, Stephanie, additional, Blue, Elizabeth, additional, Bohnsack, John, additional, Bonnenmann, Carsten, additional, Bonner, Devon, additional, Botto, Lorenzo, additional, Boyd, Brenna, additional, Briere, Lauren C., additional, Brokamp, Elly, additional, Brown, Gabrielle, additional, Burke, Elizabeth A., additional, Burrage, Lindsay C., additional, Butte, Manish J., additional, Byers, Peter, additional, Byrd, William E., additional, Carey, John, additional, Carrasquillo, Olveen, additional, Peter Chang, Ta Chen, additional, Chanprasert, Sirisak, additional, Chao, Hsiao-Tuan, additional, Clark, Gary D., additional, Coakley, Terra R., additional, Cobban, Laurel A., additional, Cogan, Joy D., additional, Coggins, Matthew, additional, Cole, F Sessions, additional, Colley, Heather A., additional, Cooper, Cynthia M., additional, Craigen, William J., additional, Crouse, Andrew B., additional, Cunningham, Michael, additional, D'Souza, Precilla, additional, Dai, Hongzheng, additional, Dasari, Surendra, additional, Davids, Mariska, additional, Dayal, Jyoti G., additional, Deardorff, Matthew, additional, Dell'Angelica, Esteban C., additional, Dhar, Shweta U., additional, Dipple, Katrina, additional, Doherty, Daniel, additional, Dorrani, Naghmeh, additional, Douine, Emilie D., additional, Draper, David D., additional, Duncan, Laura, additional, Earl, Dawn, additional, Eckstein, David J., additional, Emrick, Lisa T., additional, Eng, Christine M., additional, Esteves, Cecilia, additional, Estwick, Tyra, additional, Falk, Marni, additional, Fernandez, Liliana, additional, Ferreira, Carlos, additional, Fieg, Elizabeth L., additional, Findley, Laurie C., additional, Fisher, Paul G., additional, Fogel, Brent L., additional, Forghani, Irman, additional, Fresard, Laure, additional, Gahl, William A., additional, Glass, Ian, additional, Godfrey, Rena A., additional, Golden-Grant, Katie, additional, Goldman, Alica M., additional, Goldstein, David B., additional, Grajewski, Alana, additional, Groden, Catherine A., additional, Gropman, Andrea L., additional, Gutierrez, Irma, additional, Hahn, Sihoun, additional, Hamid, Rizwan, additional, Hanchard, Neil A., additional, Hassey, Kelly, additional, Hayes, Nichole, additional, High, Frances, additional, Hing, Anne, additional, Hisama, Fuki M., additional, Holm, Ingrid A., additional, Hom, Jason, additional, Horike-Pyne, Martha, additional, Huang, Alden, additional, Huang, Yong, additional, Isasi, Rosario, additional, Jamal, Fariha, additional, Jarvik, Gail P., additional, Jarvik, Jeffrey, additional, Jayadev, Suman, additional, Johnston, Jean M., additional, Karaviti, Lefkothea, additional, Kelley, Emily G., additional, Kennedy, Jennifer, additional, Kiley, Dana, additional, Kohane, Isaac S., additional, Kohler, Jennefer N., additional, Krakow, Deborah, additional, Krasnewich, Donna M., additional, Kravets, Elijah, additional, Korrick, Susan, additional, Koziura, Mary, additional, Krier, Joel B., additional, Lalani, Seema R., additional, Lam, Byron, additional, Lam, Christina, additional, Lanpher, Brendan C., additional, Lanza, Ian R., additional, Lau, C Christopher, additional, LeBlanc, Kimberly, additional, Lee, Brendan H., additional, Lee, Hane, additional, Levitt, Roy, additional, Lewis, Richard A., additional, Lincoln, Sharyn A., additional, Liu, Pengfei, additional, Liu, Xue Zhong, additional, Longo, Nicola, additional, Loo, Sandra K., additional, Loscalzo, Joseph, additional, Maas, Richard L., additional, Macnamara, Ellen F., additional, MacRae, Calum A., additional, Maduro, Valerie V., additional, Majcherska, Marta M., additional, Christine V Malicdan, May, additional, Mamounas, Laura A., additional, Manolio, Teri A., additional, Mao, Rong, additional, Maravilla, Kenneth, additional, Markello, Thomas C., additional, Marom, Ronit, additional, Marth, Gabor, additional, Martin, Beth A., additional, Martin, Martin G., additional, Martínez-Agosto, Julian A., additional, Marwaha, Shruti, additional, McCauley, Jacob, additional, McCormack, Colleen E., additional, McCray, Alexa T., additional, Mefford, Heather, additional, Merritt, J Lawrence, additional, Might, Matthew, additional, Mirzaa, Ghayda, additional, Morava, Eva, additional, Moretti, Paolo M., additional, Morimoto, Marie, additional, Mulvihill, John J., additional, Murdock, David R., additional, Nakano-Okuno, Mariko, additional, Nath, Avi, additional, Nelson, Stan F., additional, Newman, John H., additional, Nicholas, Sarah K., additional, Nickerson, Deborah, additional, Nieves-Rodriguez, Shirley, additional, Novacic, Donna, additional, Oglesbee, Devin, additional, Orengo, James P., additional, Pace, Laura, additional, Pak, Stephen, additional, Pallais, J Carl, additional, Papp, Jeanette C., additional, Parker, Neil H., additional, Phillips, John A., additional, Posey, Jennifer E., additional, Potocki, Lorraine, additional, Pusey, Barbara N., additional, Quinlan, Aaron, additional, Raskind, Wendy, additional, Raja, Archana N., additional, Rao, Deepak A., additional, Renteria, Genecee, additional, Reuter, Chloe M., additional, Rives, Lynette, additional, Robertson, Amy K., additional, Rodan, Lance H., additional, Rosenfeld, Jill A., additional, Rosenwasser, Natalie, additional, Ruzhnikov, Maura, additional, Sacco, Ralph, additional, Sampson, Jacinda B., additional, Samson, Susan L., additional, Saporta, Mario, additional, Scott, C Ron, additional, Schaechter, Judy, additional, Schedl, Timothy, additional, Scott, Daryl A., additional, Sharma, Prashant, additional, Shin, Jimann, additional, Signer, Rebecca, additional, Sillari, Catherine H., additional, Silverman, Edwin K., additional, Sinsheimer, Janet S., additional, Sisco, Kathy, additional, Smith, Edward C., additional, Smith, Kevin S., additional, Solem, Emily, additional, Solnica-Krezel, Lilianna, additional, Stoler, Joan M., additional, Stong, Nicholas, additional, Sullivan, Jennifer A., additional, Sun, Angela, additional, Sutton, Shirley, additional, Sweetser, David A., additional, Sybert, Virginia, additional, Tabor, Holly K., additional, Tamburro, Cecelia P., additional, Tekin, Mustafa, additional, Telischi, Fred, additional, Thorson, Willa, additional, Tifft, Cynthia J., additional, Toro, Camilo, additional, Tran, Alyssa A., additional, Tucker, Brianna M., additional, Urv, Tiina K., additional, Vanderver, Adeline, additional, Velinder, Matt, additional, Viskochil, Dave, additional, Vogel, Tiphanie P., additional, Wahl, Colleen E., additional, Wallace, Stephanie, additional, Walley, Nicole M., additional, Walsh, Chris A., additional, Walker, Melissa, additional, Wambach, Jennifer, additional, Wan, Jijun, additional, Wang, Lee-Kai, additional, Wangler, Michael F., additional, Ward, Patricia A., additional, Wegner, Daniel, additional, Wener, Mark, additional, Wenger, Tara, additional, Perry, Katherine Wesseling, additional, Westerfield, Monte, additional, Wheeler, Matthew T., additional, Whitlock, Jordan, additional, Wolfe, Lynne A., additional, Woods, Jeremy D., additional, Yamamoto, Shinya, additional, Yang, John, additional, Yu, Guoyun, additional, Zastrow, Diane B., additional, Zhao, Chunli, additional, Zuchner, Stephan, additional, Ambrose, J.C., additional, Arumugam, P., additional, Baple, E.L., additional, Bleda, M., additional, Boardman-Pretty, F., additional, Boissiere, J.M., additional, Boustred, C.R., additional, Caulfield, M.J., additional, Chan, G.C., additional, Craig, C.E.H., additional, Daugherty, L.C., additional, de Burca, A., additional, Devereau, A., additional, Elgar, G., additional, Foulger, R.E., additional, Fowler, T., additional, FurióTarí, P., additional, Hackett, J.M., additional, Halai, D., additional, Hamblin, A., additional, Henderson, S., additional, Holman, J.E., additional, Hubbard, T.J.P., additional, Ibáñez, K., additional, Jackson, R., additional, Jones, L.J., additional, Kasperaviciute, D., additional, Kayikci, M., additional, Lahnstein, L., additional, Lawson, K., additional, Leigh, S.E.A., additional, Leong, I.U.S., additional, Lopez, F.J., additional, MaleadyCrowe, F., additional, Mason, J., additional, McDonagh, E.M., additional, Moutsianas, L., additional, Mueller, M., additional, Murugaesu, N., additional, Need, A.C., additional, Odhams, C.A., additional, Patch, C., additional, Perez-Gil, D., additional, Polychronopoulos, D., additional, Pullinger, J., additional, Rahim, T., additional, Rendon, A., additional, Riesgo-Ferreiro, P., additional, Rogers, T., additional, Ryten, M., additional, Savage, K., additional, Sawant, K., additional, Scott, R.H., additional, Siddiq, A., additional, Sieghart, A., additional, Smedley, D., additional, Smith, K.R., additional, Sosinsky, A., additional, Spooner, W., additional, Stevens, H.E., additional, Stuckey, A., additional, Sultana, R., additional, Thomas, E.R.A., additional, Thompson, S.R., additional, Tucci, A., additional, Walsh, E., additional, Watters, S.A., additional, Welland, M.J., additional, Williams, E., additional, and Witkowska, K., additional

Published
2023
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37. Supplemental Table 4 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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38. Supplemental Table 6 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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39. Supplemental Table 7 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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40. Supplemental Figure 3 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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41. Supplemental Table 2 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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42. Supplemental Figure 2 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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43. Supplemental Table 1 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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44. Data from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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45. Supplemental Table 5 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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46. Supplemental Table 3 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
Full Text
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47. Supplemental Figure 1 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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48. Supplemental Figure 4 from Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

Author

Yu, Ming, primary, Carter, Kelly T., primary, Baker, Kelsey K., primary, Redman, Mary W., primary, Wang, Ting, primary, Vickers, Kathy, primary, Li, Christopher I., primary, Cohen, Stacey A., primary, Krane, Mukta, primary, Ose, Jennifer, primary, Gigic, Biljana, primary, Figueiredo, Jane C., primary, Toriola, Adetunji T., primary, Siegel, Erin M., primary, Shibata, David, primary, Schneider, Martin, primary, Ulrich, Cornelia M., primary, Dzubinski, Lynda A., primary, Schoen, Robert E., primary, and Grady, William M., primary

Published
2023
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49. Beyond Getting Rid of Stupid Stuff in the Electronic Health Record (Beyond-GROSS): Protocol for a User-Centered, Mixed-Method Intervention to Improve the Electronic Health Record System

Author

Otokiti, Ahmed Umar, Craven, Catherine K, Shetreat-Klein, Avniel, Cohen, Stacey, and Darrow, Bruce

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundUp to 60% of health care providers experience one or more symptoms of burnout. Perceived clinician burden resulting in burnout arises from factors such as electronic health record (EHR) usability or lack thereof, perceived loss of autonomy, and documentation burden leading to less clinical time with patients. Burnout can have detrimental effects on health care quality and contributes to increased medical errors, decreased patient satisfaction, substance use, workforce attrition, and suicide. ObjectiveThis project aims to improve the user-centered design of the EHR by obtaining direct input from clinicians about deficiencies. Fixing identified deficiencies via user-centered design has the potential to improve usability, thereby increasing satisfaction by reducing EHR-induced burnout. MethodsQuantitative and qualitative data will be obtained from clinician EHR users. The input will be received through a form built in a REDCap database via a link embedded in the home page of the EHR. The REDCap data will be analyzed in 2 main dimensions, based on nature of the input, what section of the EHR is affected, and what is required to fix the issue(s). Identified issues will be escalated to relevant stakeholders responsible for rectifying the problems identified. Data analysis, project evaluation, and lessons learned from the evaluation will be incorporated in a Plan-Do-Study-Act (PDSA) manner every 4-6 weeks. ResultsThe pilot phase of the study began in October 2020 in the Gastroenterology Division at Mount Sinai Hospital, New York City, NY, which includes 39 physicians and 15 nurses. The pilot is expected to run over a 4-6–month period. The results of the REDCap data analysis will be reported within 1 month of completing the pilot phase. We will analyze the nature of requests received and the impact of rectified issues on the clinician EHR user. We expect that the results will reveal which sections of the EHR have the highest deficiencies while also highlighting issues about workflow difficulties. Perceived impact of the project on provider engagement, patient safety, and workflow efficiency will also be captured by evaluation survey and other qualitative methods where possible. ConclusionsThe project aims to improve user-centered design of the EHR by soliciting direct input from clinician EHR users. The ultimate goal is to improve efficiency, reduce EHR inefficiencies with the possibility of improving staff engagement, and lessen EHR-induced clinician burnout. Our project implementation includes using informatics expertise to achieve the desired state of a learning health system as recommended by the National Academy of Medicine as we facilitate feedback loops and rapid cycles of improvement. International Registered Report Identifier (IRRID)PRR1-10.2196/25148

Published
2021
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