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274 results on '"Cogan E"'

1. Un cow-boy est passé par là

Author

Engel, H., primary, Cudia, A., additional, Rimachi, R., additional, Schmitz, L., additional, Gerain, J., additional, De Backer, D., additional, Cogan, E., additional, and David, C., additional

Published
2023
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3. [Skin ulcerations, melanoderma and dyspnea].

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de pneumologie, Wouters, A, Andrianne, M, Wellemans, I, Dahlqvist, Caroline, Gerain, J, Cogan, E, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de pneumologie, Wouters, A, Andrianne, M, Wellemans, I, Dahlqvist, Caroline, Gerain, J, and Cogan, E

Published
2023

5. [Skin ulcerations, melanoderma and dyspnea]

Author

Wouters, A, Andrianne, M, Wellemans, I, Dahlqvist, Caroline, Gerain, J, Cogan, E, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de pneumologie

Subjects
Dyspnea, Mélanodermie, Amyopathique, Dermatomyosite, Humans, Anti MDA5, Dermatomyositis, Autoantibodies
Published
2023

14. A code is afloat!

Author

Cogan, E.

Subjects
Riddles -- Tests, problems and exercises, General interest
Abstract

What do boats do when they get sick? To figure out the riddle answer below, use the code at right. They go to the [...]

Published
2016

15. Une histoire empérique, polémique : à l’aise !

Author

Vandeputte, M., primary, Couturier, B., additional, Vandergheynst, F., additional, Maerevoet, M., additional, Jullie, M.-L., additional, Kolivras, A., additional, Fontanges, Q., additional, Verset, L., additional, André, J., additional, Cogan, E., additional, and Boysson, H., additional

Published
2017
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20. Bien, bien, bien…

Author

Abbara, S., primary, Bachmeyer, C., additional, Stankovic Stojanovic, K., additional, Amselem, S., additional, Grateau, G., additional, Georgin-Lavialle, S., additional, Couturier, B., additional, and Cogan, E., additional

Published
2015
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22. Pulmonary granulomatous necrotizing vasculitis: an extra-intestinal manifestation of ulcerative colitis or Wegener's granulomatosis?

Author

ULB - Laboratoire de Physiologie, UCL - Autre, Ouazzani, A, Sokolow, Y, Hanebaly, M, Rondelet, Benoît, Patino, M Ruiz, Remmelink, Myriam, Jacobovitz, D, Cappello, M, Cogan, E, ULB - Laboratoire de Physiologie, UCL - Autre, Ouazzani, A, Sokolow, Y, Hanebaly, M, Rondelet, Benoît, Patino, M Ruiz, Remmelink, Myriam, Jacobovitz, D, Cappello, M, and Cogan, E

Abstract

Respiratory symptoms are rare manifestations of ulcerative colitis as well as intestinal manifestations in Wegener granulomatosis. We report the case of a 17-year old man previously diagnosed as having ulcerative colitis who presented with diffuse thoracic pain. Hypermetabolic pulmonary nodules were discovered at the positron emission tomographic scan. Necrotizing granulomatous vasculitis was demonstrated at lung biopsy. In this paper, we describe the association between pulmonary nodules and ulcerative colitis and we discuss the possibility of an overlap syndrome between ulcerative colitis and Wegener granulomatosis.

Published
2011

26. A pilot study of mycophenolate mofetil combined to intravenous methylprednisolone pulses and oral low-dose glucocorticoids in severe early systemic sclerosis.

Author

UCL - MD/MINT - Département de médecine interne, UCL - (SLuc) Service de rhumatologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Centre du cancer, UCL - MD/RAIM - Département de radiologie et d'imagerie médicale, Vanthuyne, Marie, Blockmans, D., Westhovens, Rene, Roufosse, F, Cogan, E, Coche, Emmanuel, Nzeusseu Toukap, A, Depresseux, Geneviève, Houssiau, Frédéric, UCL - MD/MINT - Département de médecine interne, UCL - (SLuc) Service de rhumatologie, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Centre du cancer, UCL - MD/RAIM - Département de radiologie et d'imagerie médicale, Vanthuyne, Marie, Blockmans, D., Westhovens, Rene, Roufosse, F, Cogan, E, Coche, Emmanuel, Nzeusseu Toukap, A, Depresseux, Geneviève, and Houssiau, Frédéric

Abstract

OBJECTIVE: This pilot study was aimed at evaluating the efficacy and safety of a protocol-based treatment strategy combining mycophenolate mofetil (MMF), intravenous (IV) methylprednisolone (MP) pulses and low-dose glucocorticoids (GC) in early systemic sclerosis (SSc) patients suffering from either active interstitial lung disease (ILD) or extensive skin disease. PATIENTS AND METHODS: Sixteen SSc patients were recruited in the study, 9 based on the severity of their skin involvement (modified Rodnan total skin score [TSS] >or= 15) and 7 based on the presence of active ILD. Patients received 3 consecutive daily IV MP pulses, followed by 5 additional monthly IV MP pulses. MMF (0.5 g bid for one week; then, 1 g bid) and low-dose (5-10 mg/day) oral prednisolone were prescribed for one year. Patients were assessed at baseline, month 6 and 12. Statistics were by ANOVA. RESULTS: TSS and Health Assessment Questionnaire significantly improved over time. In ILD patients, the vital capacity, forced expiratory volume in one second and carbon monoxide diffusing capacity significantly improved. Although the difference was not statistically significant, ground glass lesions decreased, based on semi-quantitative planimetry analyses performed on chest high-resolution computerized tomography. Toxicity was low and none of the patients suffered from renal crisis. CONCLUSION: The results of this pilot study suggest that the combination of MMF, IV MP and low-dose GC might achieve good clinical, functional and radiological results in patients suffering from severe early SSc.

Published
2007

38. T-cell receptor-independent activation of clonal Th2 cells associated with chronic hypereosinophilia

Author

UCL - FSA/INGI - Département d'ingénierie informatique, Roufosse, F, Schandene, L., Sibille, Cécile, Kennes, B, Efira, A., Cogan, E, Goldman, M., UCL - FSA/INGI - Département d'ingénierie informatique, Roufosse, F, Schandene, L., Sibille, Cécile, Kennes, B, Efira, A., Cogan, E, and Goldman, M.

Abstract

We recently observed a clonal expansion of CD3(-)CD4(+) T cells secreting Th2-type cytokines in patients presenting chronic hypereosinophilia. As clonal T cells isolated from such patients did not spontaneously secrete cytokines in vitro, we reasoned that costimulatory signals delivered by antigen-presenting cells might be required to induce their full activation. To address this question, we investigated in two such patients the responses of CD3(-)CD4+ T cells to dendritic cells (DC). DC elicited proliferation and production of interleukin-5 (IL-5) and IL-13 by clonal cells from patient 1 and upregulated their expression of CD25 (IL-2R-alpha). These effects were abolished when blocking monoclonal antibodies (MoAbs) against IL-2R-alpha and IL-2 were added to cocultures, indicating critical involvement of an autocrine IL-2/IL-2R pathway. Cells from patient 2 were stimulated by DC to produce Th2 cytokines only when rIL-2 or rIL-15 was added to cocultures. In both patients, addition of inhibitory MoAbs against B7-1/B7-2 or CD2 to cocultures resulted in dramatic reduction of cytokine production and inhibited CD25 upregulation. Thus, TCR/CD3-independent activation of clonal Th2 cells by DC is an IL-2-dependent process, which requires signaling through CD2 and CD28. (C) 1999 by The American Society of Hematology.

Published
1999

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