289 results on '"Clurman, Bruce E."'
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2. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
3. Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism
4. Ras Activity Regulates Cyclin E Degradation by the Fbw7 Pathway
5. Terminal Osteoblast Differentiation, Mediated by Runx2 and p27 KIP1 , Is Disrupted in Osteosarcoma
6. The Fbw7 Tumor Suppressor Regulates Glycogen Synthase Kinase 3 Phosphorylation-Dependent c-Myc Protein Degradation
7. Identification of Oncogenes Collaborating with p27 Kip1 Loss by Insertional Mutagenesis and High-Throughput Insertion Site Analysis
8. Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice
9. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells
10. Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
11. A Novel Function for Cyclin E in Cell Cycle Progression
12. Analysis of gene expression, copy number and palindrome formation with a DT40 enriched CDNA microarray
13. New Insights into the Tumor Suppression Function of P27 Kip1
14. Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins
15. Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation
16. Isoform- and Cell Cycle-Dependent Substrate Degradation by the Fbw7 Ubiquitin Ligase
17. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
18. Author response: Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
19. Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor
20. Hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute myeloid leukemia arising from myelodysplastic syndrome: similar outcomes in patients with de novo disease and disease following prior therapy or antecedent hematologic disorders
21. Regulation of cell proliferation in a stratified culture system of epithelial cells from prostate tissue
22. Ubiquitin-Independent Degradation of Cell-Cycle Inhibitors by the REGγ Proteasome
23. Cyclin E in normal and neoplastic cell cycles
24. Terminal osteoblast differentiation, mediated by runx2 and [p27.sup.KIP1], is disrupted in osteosarcoma
25. Identification of oncogenes collaborating with [p27.sup.Kip1] loss by insertional mutagenesis and high-throughput insertion site analysis
26. Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import
27. A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation
28. The SV40 Large T Antigen Contains a Decoy Phosphodegron That Mediates Its Interactions with Fbw7/hCdc4
29. A mouse model for cyclin E-dependent genetic instability and tumorigenesis
30. Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins
31. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
32. Recognition of Phosphodegron Motifs in Human Cyclin E by the SCFFbw7 Ubiquitin Ligase
33. N-Acetylation and Ubiquitin-Independent Proteasomal Degradation of p21 Cip1
34. Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation
35. Cycling without CDK2?
36. Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP
37. The CDKN2A Tumor-Suppressor Locus - A Tale of Two Proteins
38. p53 and p21 Form an Inducible Barrier that Protects Cells against Cyclin E-cdk2 Deregulation
39. Npap60/Nup50 Is a Tri-Stable Switch that Stimulates Importin-α:β-Mediated Nuclear Protein Import
40. Fbw7/hCDC4 dimerization regulates its substrate interactions
41. Proteasomal Turnover of p21 Cip1 Does Not Require p21 Cip1 Ubiquitination
42. RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions
43. The p27Kip1 Tumor Suppressor and Multi-Step Tumorigenesis
44. The p27Kipl Tumor Suppressor and Multi-Step Tumorigenesis
45. Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo
46. Discovery of an oncogenic activity in [p27.sup.Kip1] that causes stem cell expansion and a multiple tumor phenotype
47. Abstract 1030: Metabolic reprogramming caused by mutations of the Fbw7 ubiquitin ligase in colorectal cancer
48. Abstract 2341:In situlabelling identifies a novel landscape of nuclear CDK2 substrates
49. Abstract 308: The PP2A-B56 phosphatase opposes cyclin E autocatalytic degradation via site-specific dephosphorylation
50. The miR-106a~363Xpcl1 miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27Kip1 cell cycle inhibitor
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