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2. Effect of BMI on safety of bariatric surgery during the COVID-19 pandemic, procedure choice, and safety protocols – An analysis from the GENEVA Study

Author

Pędziwiatr, Michał, Major, Piotr, Zarzycki, Piotr, Pantelis, Athanasios, Lapatsanis, Dimitris P., Stravodimos, Georgios, Matthys, Chris, Focquet, Marc, Vleeschouwers, Wouter, Spaventa, Antonio G., Zerrweck, Carlos, Vitiello, Antonio, Berardi, Giovanna, Musella, Mario, Sanchez-Meza, Alberto, Cantu, Felipe J., Jr, Mora, Fernando, Cantu, Marco A., Katakwar, Abhishek, Reddy, D. Nageshwar, Elmaleh, Haitham, Hassan, Mohammad, Elghandour, Abdelrahman, Elbanna, Mohey, Osman, Ahmed, Khan, Athar, Layani, Laurent, Kiran, Nalini, Velikorechin, Andrey, Solovyeva, Maria, Melali, Hamid, Shahabi, Shahab, Agrawal, Ashish, Shrivastava, Apoorv, Sharma, Ankur, Narwaria, Bhavya, Narwaria, Mahendra, Raziel, Asnat, Sakran, Nasser, Susmallian, Sergio, Karagöz, Levent, Akbaba, Murat, Pişkin, Salih Zeki, Balta, Ahmet Ziya, Senol, Zafer, Manno, Emilio, Iovino, Michele Giuseppe, Qassem, Mohamed, Arana-Garza, Sebastián, Povoas, Heitor P., Vilas-Boas, Marcos Leão, Li, Alan, Ammori, Basil J., Balamoun, Hany, Salman, Mohammed, Nasta, Amrit Manik, Goel, Ramen, Sánchez-Aguilar, Hugo, Herrera, Miguel F., Abou-Mrad, Adel, Cloix, Lucie, Mazzini, Guilherme Silva, Kristem, Leonardo, Lazaro, Andre, Campos, Jose, Bernardo, Joaquín, González, Jesús, Trindade, Carlos, Viveiros, Octávio, Ribeiro, Rui, Goitein, David, Hazzan, David, Segev, Lior, Beck, Tamar, Reyes, Hernán, Monterrubio, Jerónimo, García, Paulina, Benois, Marine, Kassir, Radwan, Contine, Alessandro, Elshafei, Moustafa, Aktas, Sueleyman, Weiner, Sylvia, Heidsieck, Till, Level, Luis, Pinango, Silvia, Ortega, Patricia Martinez, Moncada, Rafael, Valenti, Victor, Vlahović, Ivan, Boras, Zdenko, Liagre, Arnaud, Martini, Francesco, Juglard, Gildas, Motwani, Manish, Saggu, Sukhvinder Singh, Momani, Hazem Al, López, Luis Adolfo Aceves, Cortez, María Angelina Contreras, Zavala, Rodrigo Aceves, D'Haese, Christine, Kempeneers, Ivo, Himpens, Jacques, Lazzati, Andrea, Paolino, Luca, Bathaei, Sarah, Bedirli, Abdulkadir, Yavuz, Aydın, Büyükkasap, Çağrı, Özaydın, Safa, Kwiatkowski, Andrzej, Bartosiak, Katarzyna, Walędziak, Maciej, Santonicola, Antonella, Angrisani, Luigi, Iovino, Paola, Palma, Rossella, Iossa, Angelo, Boru, Cristian Eugeniu, Angelis, Francesco De, Silecchia, Gianfranco, Hussain, Abdulzahra, Balchandra, Srivinasan, Coltell, Izaskun Balciscueta, Pérez, Javier Lorenzo, Bohra, Ashok, Awan, Altaf K., Madhok, Brijesh, Leeder, Paul C., Awad, Sherif, Al-Khyatt, Waleed, Shoma, Ashraf, Elghadban, Hosam, Ghareeb, Sameh, Mathews, Bryan, Kurian, Marina, Larentzakis, Andreas, Vrakopoulou, Gavriella Zoi, Albanopoulos, Konstantinos, Bozdag, Ahemt, Lale, Azmi, Kirkil, Cuneyt, Dincer, Mursid, Bashir, Ahmad, Haddad, Ashraf, Hijleh, Leen Abu, Zilberstein, Bruno, de Marchi, Danilo Dallago, Souza, Willy Petrini, Brodén, Carl Magnus, Gislason, Hjörtur, Shah, Kamran, Ambrosi, Antonio, Pavone, Giovanna, Tartaglia, Nicola, Kumari Kona, S. Lakshmi, Kalyan, K., Perez, Cesar Ernesto Guevara, Botero, Miguel Alberto Forero, Covic, Adrian, Timofte, Daniel, Maxim, Madalina, Faraj, Dashti, Tseng, Larissa, Liem, Ronald, Ören, Gürdal, Dilektasli, Evren, Yalcin, Ilker, AlMukhtar, Hudhaifa, Hadad, Mohammed Al, Mohan, Rasmi, Arora, Naresh, Bedi, Digvijaysingh, Rives-Lange, Claire, Chevallier, Jean-Marc, Poghosyan, Tigran, Sebbag, Hugues, Zinaï, Lamia, Khaldi, Saadi, Mauchien, Charles, Mazza, Davide, Dinescu, Georgiana, Rea, Bernardo, Pérez-Galaz, Fernando, Zavala, Luis, Besa, Anais, Curell, Anna, Balibrea, Jose M., Vaz, Carlos, Galindo, Luis, Silva, Nelson, Caballero, José Luis Estrada, Sebastian, Sergio Ortiz, Marchesini, João Caetano Dallegrave, da Fonseca Pereira, Ricardo Arcanjo, Sobottka, Wagner Herbert, Fiolo, Felipe Eduardo, Turchi, Matias, Coelho, Antonio Claudio Jamel, Zacaron, Andre Luis, Barbosa, André, Quinino, Reynaldo, Menaldi, Gabriel, Paleari, Nicolás, Martinez-Duartez, Pedro, de Aragon Ramírez de Esparza, Gabriel Martínez, Esteban, Valentin Sierra, Torres, Antonio, Garcia-Galocha, Jose Luis, Josa, Miguel, Pacheco-Garcia, Jose Manuel, Mayo-Ossorio, Maria Angeles, Chowbey, Pradeep, Soni, Vandana, de Vasconcelos Cunha, Hercio Azevedo, Castilho, Michel Victor, Ferreira, Rafael Meneguzzi Alves, Barreiro, Thiago Alvim, Charalabopoulos, Alexandros, Sdralis, Elias, Davakis, Spyridon, Bomans, Benoit, Dapri, Giovanni, Belle, Koenraad Van, Takieddine, Mazen, Vaneukem, Pol, Karaca, Esma Seda Akalın, Karaca, Fatih Can, Sumer, Aziz, Peksen, Caghan, Savas, Osman Anil, Chousleb, Elias, Elmokayed, Fahad, Fakhereldin, Islam, Aboshanab, Hany Mohamed, Swelium, Talal, Gudal, Ahmad, Gamloo, Lamees, Ugale, Ayushka, Ugale, Surendra, Boeker, Clara, Reetz, Christian, Hakami, Ibrahim Ali, Mall, Julian, Alexandrou, Andreas, Baili, Efstratia, Bodnar, Zsolt, Maleckas, Almantas, Gudaityte, Rita, Guldogan, Cem Emir, Gundogdu, Emre, Ozmen, Mehmet Mahir, Thakkar, Deepti, Dukkipati, Nandakishore, Shah, Poonam Shashank, Shah, Shashank Subhashchandra, Shah, Simran Shashank, Adil, Md Tanveer, Jambulingam, Periyathambi, Mamidanna, Ravikrishna, Whitelaw, Douglas, Jain, Vigyan, Veetil, Deepa Kizhakke, Wadhawan, Randeep, Torres, Max, Tinoco, Tabata, Leclercq, Wouter, Romeijn, Marleen, van de Pas, Kelly, Alkhazraji, Ali K., Taha, Safwan A., Ustun, Murat, Yigit, Taner, Inam, Aatif, Burhanulhaq, Muhammad, Pazouki, Abdolreza, Eghbali, Foolad, Kermansaravi, Mohammad, Jazi, Amir Hosein Davarpanah, Mahmoudieh, Mohsen, Mogharehabed, Neda, Tsiotos, Gregory, Stamou, Konstantinos, Barrera Rodriguez, Francisco J, Rojas Navarro, Marco A., MOhamed Torres, Omar, Martinez, Sergio Lopez, Tamez, Elda Rocio Maltos, Millan Cornejo, Gustavo A., Flores, Jose Eduardo Garcia, Mohammed, Diya Aldeen, Elfawal, Mohamad Hayssam, Shabbir, Asim, Guowei, Kim, So, Jimmy By, Kaplan, Elif Tuğçe, Kaplan, Mehmet, Kaplan, Tuğba, Pham, DangTuan, Rana, Gurteshwar, Kappus, Mojdeh, Gadani, Riddish, Kahitan, Manish, Pokharel, Koshish, Osborne, Alan, Pournaras, Dimitri, Hewes, James, Napolitano, Errichetta, Chiappetta, Sonja, Bottino, Vincenzo, Dorado, Evelyn, Schoettler, Axel, Gaertner, Daniel, Fedtke, Katharina, Aguilar-Espinosa, Francisco, Aceves-Lozano, Saul, Balani, Alessandro, Nagliati, Carlo, Pennisi, Damiano, Rizzi, Andrea, Frattini, Francesco, Foschi, Diego, Benuzzi, Laura, Parikh, Chirag, Shah, Harshil, Pinotti, Enrico, Montuori, Mauro, Borrelli, Vincenzo, Dargent, Jerome, Copaescu, Catalin A, Hutopila, Ionut, Smeu, Bogdan, Witteman, Bart, Hazebroek, Eric, Deden, Laura, Heusschen, Laura, Okkema, Sietske, Aufenacker, Theo, den Hengst, Willem, Vening, Wouter, van der Burgh, Yonta, Ghazal, Ahmad, Ibrahim, Hamza, Niazi, Mourad, Alkhaffaf, Bilal, Altarawni, Mohammad, Cesana, Giovanni Carlo, Anselmino, Marco, Uccelli, Matteo, Olmi, Stefano, Stier, Christine, Akmanlar, Tahsin, Sonnenberg, Thomas, Schieferbein, Uwe, Marcolini, Alejandro, Awruch, Diego, Vicentin, Marco, de Souza Bastos, Eduardo Lemos, Gregorio, Samuel Azenha, Ahuja, Anmol, Mittal, Tarun, Bolckmans, Roel, Wiggins, Tom, Baratte, Clément, Wisnewsky, Judith Aron, Genser, Laurent, Chong, Lynn, Taylor, Lillian, Ward, Salena, Hi, Michael W., Heneghan, Helen, Fearon, Naomi, Plamper, Andreas, Rheinwalt, Karl, Geoghegan, Justin, Ng, Kin Cheung, Kaseja, Krzysztof, Kotowski, Maciej, Samarkandy, Tarig A., Leyva-Alvizo, Adolfo, Corzo-Culebro, Lourdes, Wang, Cunchuan, Yang, Wah, Dong, Zhiyong, Riera, Manel, Jain, Rajesh, Hamed, Hosam, Said, Mohammed, Zarzar, Katia, Garcia, Manuel, Türkçapar, Ahmet Gökhan, Şen, Ozan, Baldini, Edoardo, Conti, Luigi, Wietzycoski, Cacio, Lopes, Eduardo, Pintar, Tadeja, Salobir, Jure, Aydin, Cengiz, Atici, Semra Demirli, Ergin, Anıl, Ciyiltepe, Huseyin, Bozkurt, Mehmet Abdussamet, Kizilkaya, Mehmet Celal, Onalan, Nezihe Berrin Dodur, Binti Ahmad Zuber, Mariana Nabila, Wong, Wei Jin, Garcia, Amador, Vidal, Laura, Beisani, Marc, Pasquier, Jorge, Vilallonga, Ramon, Sharma, Sharad, Parmar, Chetan, Lee, Lyndcie, Sufi, Pratik, Sinan, Hüseyin, Saydam, Mehmet, Singhal, Rishi, Omar, Islam, Ludwig, Christian, Tahrani, Abd A., and Mahawar, Kamal

Published
2022
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3. Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study

Author

Chasseloup, Fanny, Bourdeau, Isabelle, Tabarin, Antoine, Regazzo, Daniela, Dumontet, Charles, Ladurelle, Nataly, Tosca, Lucie, Amazit, Larbi, Proust, Alexis, Scharfmann, Raphael, Mignot, Tiphaine, Fiore, Frédéric, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Maiter, Dominique, Young, Jacques, Lecoq, Anne-Lise, Deméocq, Vianney, Salenave, Sylvie, Lefebvre, Hervé, Cloix, Lucie, Emy, Philippe, Dessailloud, Rachel, Vezzosi, Delphine, Scaroni, Carla, Barbot, Mattia, de Herder, Wouter, Pattou, François, Tétreault, Martine, Corbeil, Gilles, Dupeux, Margot, Lambert, Benoit, Tachdjian, Gérard, Guiochon-Mantel, Anne, Beau, Isabelle, Chanson, Philippe, Viengchareun, Say, Lacroix, André, Bouligand, Jérôme, and Kamenický, Peter

Published
2021
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4. OR04-4 Loss of KDM1A in Bilateral Macronodular Adrenal Hyperplasia With GIP-Dependent Cushing's Syndrome and in Acromegaly With Paradoxical GH Response to Oral Glucose

Author

Amazit, Larbi, primary, Barbot, Mattia, additional, Beau, Isabelle, additional, Bouligand, Jérôme, additional, Bourdeau, Isabelle, additional, Chanson, Philippe, additional, Cloix, Lucie, additional, Corbeil, Gilles, additional, de Herder, Wouter, additional, Deméocq, Vianney, additional, Desailloud, Rachel, additional, Dumontet, Charles, additional, Dupeux, Margot, additional, Emy, Philippe, additional, Fiore, Frederic, additional, Guiochon-Mantel, Anne, additional, Kamenicky, Peter, additional, Lacroix, André, additional, Ladurelle, Nataly, additional, Lambert, Benoit, additional, Lecoq, Anne-Lise, additional, Lefebvre, Hervé, additional, Maiter, Dominique, additional, Pattou, Francois, additional, Proust, Alexis, additional, Regazzo, Daniela, additional, Salenave, Sylvie, additional, Scaroni, Carla, additional, Scharfmann, Raphael, additional, Tabarin, Antoine, additional, Tachdjian, Gerard, additional, Tetreault, Martine, additional, Tosca, Lucie, additional, Tsagarakis, Stylianos, additional, Vassiliadi, Dimitra, additional, Vezzosi, Delphine, additional, Viengchareun, Say, additional, Young, Jacques, additional, and Chasseloup, Fanny, additional

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2022
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5. Loss of lysine demethylase KDM1A in GIP-dependent bilateral macronodular adrenal hyperplasia with Cushing's syndrome

Author

Chasseloup, Fanny, primary, Bourdeau, Isabelle, additional, Tabarin, Antoine, additional, Regazzo, Daniela, additional, Dumontet, Charles, additional, Ladurelle, Nataly, additional, Tosca, Lucie, additional, Amazit, Larbi, additional, Proust, Alexis, additional, Scharfmann, Raphael, additional, Fiore, Frederic, additional, Tsagarakis, Stylianos, additional, Vassiliadi, Dimitra, additional, Maiter, Dominique, additional, Young, Jacques, additional, Lecoq, Anne-Lise, additional, Demeocq, Vianney, additional, Salenave, Sylvie, additional, Lefebvre, Herve, additional, Cloix, Lucie, additional, Emy, Philippe, additional, Desailloud, Rachel, additional, Vezzosi, Delphine, additional, Scaroni, Carla, additional, Barbot, Mattia, additional, de, Herder Wouter, additional, Pattou, Francois, additional, Tetreault, Martine, additional, Corbeil, Gilles, additional, Dupeux, Margot, additional, Lambert, Benoit, additional, Tachdjian, Gerard, additional, Guiochon-Mantel, Anne, additional, Beau, Isabelle, additional, Chanson, Philippe, additional, Viengchareun, Say, additional, Lacroix, Andre, additional, Bouligand, Jerome, additional, and Kamenicky, Peter, additional

Published
2022
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6. Effect of BMI on safety of bariatric surgery during the COVID-19 pandemic, procedure choice, and safety protocols – An analysis from the GENEVA Study

Author

Singhal, Rishi, primary, Omar, Islam, additional, Madhok, Brijesh, additional, Ludwig, Christian, additional, Tahrani, Abd A., additional, Mahawar, Kamal, additional, Pędziwiatr, Michał, additional, Major, Piotr, additional, Zarzycki, Piotr, additional, Pantelis, Athanasios, additional, Lapatsanis, Dimitris P., additional, Stravodimos, Georgios, additional, Matthys, Chris, additional, Focquet, Marc, additional, Vleeschouwers, Wouter, additional, Spaventa, Antonio G., additional, Zerrweck, Carlos, additional, Vitiello, Antonio, additional, Berardi, Giovanna, additional, Musella, Mario, additional, Sanchez-Meza, Alberto, additional, Cantu, Felipe J., additional, Mora, Fernando, additional, Cantu, Marco A., additional, Katakwar, Abhishek, additional, Reddy, D. Nageshwar, additional, Elmaleh, Haitham, additional, Hassan, Mohammad, additional, Elghandour, Abdelrahman, additional, Elbanna, Mohey, additional, Osman, Ahmed, additional, Khan, Athar, additional, Layani, Laurent, additional, Kiran, Nalini, additional, Velikorechin, Andrey, additional, Solovyeva, Maria, additional, Melali, Hamid, additional, Shahabi, Shahab, additional, Agrawal, Ashish, additional, Shrivastava, Apoorv, additional, Sharma, Ankur, additional, Narwaria, Bhavya, additional, Narwaria, Mahendra, additional, Raziel, Asnat, additional, Sakran, Nasser, additional, Susmallian, Sergio, additional, Karagöz, Levent, additional, Akbaba, Murat, additional, Pişkin, Salih Zeki, additional, Balta, Ahmet Ziya, additional, Senol, Zafer, additional, Manno, Emilio, additional, Iovino, Michele Giuseppe, additional, Qassem, Mohamed, additional, Arana-Garza, Sebastián, additional, Povoas, Heitor P., additional, Vilas-Boas, Marcos Leão, additional, Li, Alan, additional, Ammori, Basil J., additional, Balamoun, Hany, additional, Salman, Mohammed, additional, Nasta, Amrit Manik, additional, Goel, Ramen, additional, Sánchez-Aguilar, Hugo, additional, Herrera, Miguel F., additional, Abou-Mrad, Adel, additional, Cloix, Lucie, additional, Mazzini, Guilherme Silva, additional, Kristem, Leonardo, additional, Lazaro, Andre, additional, Campos, Jose, additional, Bernardo, Joaquín, additional, González, Jesús, additional, Trindade, Carlos, additional, Viveiros, Octávio, additional, Ribeiro, Rui, additional, Goitein, David, additional, Hazzan, David, additional, Segev, Lior, additional, Beck, Tamar, additional, Reyes, Hernán, additional, Monterrubio, Jerónimo, additional, García, Paulina, additional, Benois, Marine, additional, Kassir, Radwan, additional, Contine, Alessandro, additional, Elshafei, Moustafa, additional, Aktas, Sueleyman, additional, Weiner, Sylvia, additional, Heidsieck, Till, additional, Level, Luis, additional, Pinango, Silvia, additional, Ortega, Patricia Martinez, additional, Moncada, Rafael, additional, Valenti, Victor, additional, Vlahović, Ivan, additional, Boras, Zdenko, additional, Liagre, Arnaud, additional, Martini, Francesco, additional, Juglard, Gildas, additional, Motwani, Manish, additional, Saggu, Sukhvinder Singh, additional, Momani, Hazem Al, additional, López, Luis Adolfo Aceves, additional, Cortez, María Angelina Contreras, additional, Zavala, Rodrigo Aceves, additional, D'Haese, Christine, additional, Kempeneers, Ivo, additional, Himpens, Jacques, additional, Lazzati, Andrea, additional, Paolino, Luca, additional, Bathaei, Sarah, additional, Bedirli, Abdulkadir, additional, Yavuz, Aydın, additional, Büyükkasap, Çağrı, additional, Özaydın, Safa, additional, Kwiatkowski, Andrzej, additional, Bartosiak, Katarzyna, additional, Walędziak, Maciej, additional, Santonicola, Antonella, additional, Angrisani, Luigi, additional, Iovino, Paola, additional, Palma, Rossella, additional, Iossa, Angelo, additional, Boru, Cristian Eugeniu, additional, Angelis, Francesco De, additional, Silecchia, Gianfranco, additional, Hussain, Abdulzahra, additional, Balchandra, Srivinasan, additional, Coltell, Izaskun Balciscueta, additional, Pérez, Javier Lorenzo, additional, Bohra, Ashok, additional, Awan, Altaf K., additional, Leeder, Paul C., additional, Awad, Sherif, additional, Al-Khyatt, Waleed, additional, Shoma, Ashraf, additional, Elghadban, Hosam, additional, Ghareeb, Sameh, additional, Mathews, Bryan, additional, Kurian, Marina, additional, Larentzakis, Andreas, additional, Vrakopoulou, Gavriella Zoi, additional, Albanopoulos, Konstantinos, additional, Bozdag, Ahemt, additional, Lale, Azmi, additional, Kirkil, Cuneyt, additional, Dincer, Mursid, additional, Bashir, Ahmad, additional, Haddad, Ashraf, additional, Hijleh, Leen Abu, additional, Zilberstein, Bruno, additional, de Marchi, Danilo Dallago, additional, Souza, Willy Petrini, additional, Brodén, Carl Magnus, additional, Gislason, Hjörtur, additional, Shah, Kamran, additional, Ambrosi, Antonio, additional, Pavone, Giovanna, additional, Tartaglia, Nicola, additional, Kumari Kona, S. Lakshmi, additional, Kalyan, K., additional, Perez, Cesar Ernesto Guevara, additional, Botero, Miguel Alberto Forero, additional, Covic, Adrian, additional, Timofte, Daniel, additional, Maxim, Madalina, additional, Faraj, Dashti, additional, Tseng, Larissa, additional, Liem, Ronald, additional, Ören, Gürdal, additional, Dilektasli, Evren, additional, Yalcin, Ilker, additional, AlMukhtar, Hudhaifa, additional, Hadad, Mohammed Al, additional, Mohan, Rasmi, additional, Arora, Naresh, additional, Bedi, Digvijaysingh, additional, Rives-Lange, Claire, additional, Chevallier, Jean-Marc, additional, Poghosyan, Tigran, additional, Sebbag, Hugues, additional, Zinaï, Lamia, additional, Khaldi, Saadi, additional, Mauchien, Charles, additional, Mazza, Davide, additional, Dinescu, Georgiana, additional, Rea, Bernardo, additional, Pérez-Galaz, Fernando, additional, Zavala, Luis, additional, Besa, Anais, additional, Curell, Anna, additional, Balibrea, Jose M., additional, Vaz, Carlos, additional, Galindo, Luis, additional, Silva, Nelson, additional, Caballero, José Luis Estrada, additional, Sebastian, Sergio Ortiz, additional, Marchesini, João Caetano Dallegrave, additional, da Fonseca Pereira, Ricardo Arcanjo, additional, Sobottka, Wagner Herbert, additional, Fiolo, Felipe Eduardo, additional, Turchi, Matias, additional, Coelho, Antonio Claudio Jamel, additional, Zacaron, Andre Luis, additional, Barbosa, André, additional, Quinino, Reynaldo, additional, Menaldi, Gabriel, additional, Paleari, Nicolás, additional, Martinez-Duartez, Pedro, additional, de Aragon Ramírez de Esparza, Gabriel Martínez, additional, Esteban, Valentin Sierra, additional, Torres, Antonio, additional, Garcia-Galocha, Jose Luis, additional, Josa, Miguel, additional, Pacheco-Garcia, Jose Manuel, additional, Mayo-Ossorio, Maria Angeles, additional, Chowbey, Pradeep, additional, Soni, Vandana, additional, de Vasconcelos Cunha, Hercio Azevedo, additional, Castilho, Michel Victor, additional, Ferreira, Rafael Meneguzzi Alves, additional, Barreiro, Thiago Alvim, additional, Charalabopoulos, Alexandros, additional, Sdralis, Elias, additional, Davakis, Spyridon, additional, Bomans, Benoit, additional, Dapri, Giovanni, additional, Belle, Koenraad Van, additional, Takieddine, Mazen, additional, Vaneukem, Pol, additional, Karaca, Esma Seda Akalın, additional, Karaca, Fatih Can, additional, Sumer, Aziz, additional, Peksen, Caghan, additional, Savas, Osman Anil, additional, Chousleb, Elias, additional, Elmokayed, Fahad, additional, Fakhereldin, Islam, additional, Aboshanab, Hany Mohamed, additional, Swelium, Talal, additional, Gudal, Ahmad, additional, Gamloo, Lamees, additional, Ugale, Ayushka, additional, Ugale, Surendra, additional, Boeker, Clara, additional, Reetz, Christian, additional, Hakami, Ibrahim Ali, additional, Mall, Julian, additional, Alexandrou, Andreas, additional, Baili, Efstratia, additional, Bodnar, Zsolt, additional, Maleckas, Almantas, additional, Gudaityte, Rita, additional, Guldogan, Cem Emir, additional, Gundogdu, Emre, additional, Ozmen, Mehmet Mahir, additional, Thakkar, Deepti, additional, Dukkipati, Nandakishore, additional, Shah, Poonam Shashank, additional, Shah, Shashank Subhashchandra, additional, Shah, Simran Shashank, additional, Adil, Md Tanveer, additional, Jambulingam, Periyathambi, additional, Mamidanna, Ravikrishna, additional, Whitelaw, Douglas, additional, Jain, Vigyan, additional, Veetil, Deepa Kizhakke, additional, Wadhawan, Randeep, additional, Torres, Max, additional, Tinoco, Tabata, additional, Leclercq, Wouter, additional, Romeijn, Marleen, additional, van de Pas, Kelly, additional, Alkhazraji, Ali K., additional, Taha, Safwan A., additional, Ustun, Murat, additional, Yigit, Taner, additional, Inam, Aatif, additional, Burhanulhaq, Muhammad, additional, Pazouki, Abdolreza, additional, Eghbali, Foolad, additional, Kermansaravi, Mohammad, additional, Jazi, Amir Hosein Davarpanah, additional, Mahmoudieh, Mohsen, additional, Mogharehabed, Neda, additional, Tsiotos, Gregory, additional, Stamou, Konstantinos, additional, Barrera Rodriguez, Francisco J, additional, Rojas Navarro, Marco A., additional, MOhamed Torres, Omar, additional, Martinez, Sergio Lopez, additional, Tamez, Elda Rocio Maltos, additional, Millan Cornejo, Gustavo A., additional, Flores, Jose Eduardo Garcia, additional, Mohammed, Diya Aldeen, additional, Elfawal, Mohamad Hayssam, additional, Shabbir, Asim, additional, Guowei, Kim, additional, So, Jimmy By, additional, Kaplan, Elif Tuğçe, additional, Kaplan, Mehmet, additional, Kaplan, Tuğba, additional, Pham, DangTuan, additional, Rana, Gurteshwar, additional, Kappus, Mojdeh, additional, Gadani, Riddish, additional, Kahitan, Manish, additional, Pokharel, Koshish, additional, Osborne, Alan, additional, Pournaras, Dimitri, additional, Hewes, James, additional, Napolitano, Errichetta, additional, Chiappetta, Sonja, additional, Bottino, Vincenzo, additional, Dorado, Evelyn, additional, Schoettler, Axel, additional, Gaertner, Daniel, additional, Fedtke, Katharina, additional, Aguilar-Espinosa, Francisco, additional, Aceves-Lozano, Saul, additional, Balani, Alessandro, additional, Nagliati, Carlo, additional, Pennisi, Damiano, additional, Rizzi, Andrea, additional, Frattini, Francesco, additional, Foschi, Diego, additional, Benuzzi, Laura, additional, Parikh, Chirag, additional, Shah, Harshil, additional, Pinotti, Enrico, additional, Montuori, Mauro, additional, Borrelli, Vincenzo, additional, Dargent, Jerome, additional, Copaescu, Catalin A, additional, Hutopila, Ionut, additional, Smeu, Bogdan, additional, Witteman, Bart, additional, Hazebroek, Eric, additional, Deden, Laura, additional, Heusschen, Laura, additional, Okkema, Sietske, additional, Aufenacker, Theo, additional, den Hengst, Willem, additional, Vening, Wouter, additional, van der Burgh, Yonta, additional, Ghazal, Ahmad, additional, Ibrahim, Hamza, additional, Niazi, Mourad, additional, Alkhaffaf, Bilal, additional, Altarawni, Mohammad, additional, Cesana, Giovanni Carlo, additional, Anselmino, Marco, additional, Uccelli, Matteo, additional, Olmi, Stefano, additional, Stier, Christine, additional, Akmanlar, Tahsin, additional, Sonnenberg, Thomas, additional, Schieferbein, Uwe, additional, Marcolini, Alejandro, additional, Awruch, Diego, additional, Vicentin, Marco, additional, de Souza Bastos, Eduardo Lemos, additional, Gregorio, Samuel Azenha, additional, Ahuja, Anmol, additional, Mittal, Tarun, additional, Bolckmans, Roel, additional, Wiggins, Tom, additional, Baratte, Clément, additional, Wisnewsky, Judith Aron, additional, Genser, Laurent, additional, Chong, Lynn, additional, Taylor, Lillian, additional, Ward, Salena, additional, Hi, Michael W., additional, Heneghan, Helen, additional, Fearon, Naomi, additional, Plamper, Andreas, additional, Rheinwalt, Karl, additional, Geoghegan, Justin, additional, Ng, Kin Cheung, additional, Kaseja, Krzysztof, additional, Kotowski, Maciej, additional, Samarkandy, Tarig A., additional, Leyva-Alvizo, Adolfo, additional, Corzo-Culebro, Lourdes, additional, Wang, Cunchuan, additional, Yang, Wah, additional, Dong, Zhiyong, additional, Riera, Manel, additional, Jain, Rajesh, additional, Hamed, Hosam, additional, Said, Mohammed, additional, Zarzar, Katia, additional, Garcia, Manuel, additional, Türkçapar, Ahmet Gökhan, additional, Şen, Ozan, additional, Baldini, Edoardo, additional, Conti, Luigi, additional, Wietzycoski, Cacio, additional, Lopes, Eduardo, additional, Pintar, Tadeja, additional, Salobir, Jure, additional, Aydin, Cengiz, additional, Atici, Semra Demirli, additional, Ergin, Anıl, additional, Ciyiltepe, Huseyin, additional, Bozkurt, Mehmet Abdussamet, additional, Kizilkaya, Mehmet Celal, additional, Onalan, Nezihe Berrin Dodur, additional, Binti Ahmad Zuber, Mariana Nabila, additional, Wong, Wei Jin, additional, Garcia, Amador, additional, Vidal, Laura, additional, Beisani, Marc, additional, Pasquier, Jorge, additional, Vilallonga, Ramon, additional, Sharma, Sharad, additional, Parmar, Chetan, additional, Lee, Lyndcie, additional, Sufi, Pratik, additional, Sinan, Hüseyin, additional, and Saydam, Mehmet, additional

Published
2022
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7. OR04-4 Loss of KDM1A in Bilateral Macronodular Adrenal Hyperplasia With GIP-Dependent Cushing's Syndrome and in Acromegaly With Paradoxical GH Response to Oral Glucose

Author

UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - (SLuc) Service d'endocrinologie et de nutrition, Amazit, Larbi, Barbot, Mattia, Beau, Isabelle, Bouligand, Jérôme, Bourdeau, Isabelle, Chanson, Philippe, Cloix, Lucie, Corbeil, Gilles, de Herder, Wouter, Deméocq, Vianney, Desailloud, Rachel, Dumontet, Charles, Dupeux, Margot, Emy, Philippe, Fiore, Frederic, Guiochon-Mantel, Anne, Kamenicky, Peter, Lacroix, André, Ladurelle, Nataly, Lambert, Benoit, Lecoq, Anne-Lise, Lefebvre, Hervé, Maiter, Dominique, Pattou, Francois, Proust, Alexis, Regazzo, Daniela, Salenave, Sylvie, Scaroni, Carla, Scharfmann, Raphael, Tabarin, Antoine, Tachdjian, Gerard, Tetreault, Martine, Tosca, Lucie, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Vezzosi, Delphine, Viengchareun, Say, Young, Jacques, Chasseloup, Fanny, Annual Meeting of the Endocrine Society 2022, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - (SLuc) Service d'endocrinologie et de nutrition, Amazit, Larbi, Barbot, Mattia, Beau, Isabelle, Bouligand, Jérôme, Bourdeau, Isabelle, Chanson, Philippe, Cloix, Lucie, Corbeil, Gilles, de Herder, Wouter, Deméocq, Vianney, Desailloud, Rachel, Dumontet, Charles, Dupeux, Margot, Emy, Philippe, Fiore, Frederic, Guiochon-Mantel, Anne, Kamenicky, Peter, Lacroix, André, Ladurelle, Nataly, Lambert, Benoit, Lecoq, Anne-Lise, Lefebvre, Hervé, Maiter, Dominique, Pattou, Francois, Proust, Alexis, Regazzo, Daniela, Salenave, Sylvie, Scaroni, Carla, Scharfmann, Raphael, Tabarin, Antoine, Tachdjian, Gerard, Tetreault, Martine, Tosca, Lucie, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Vezzosi, Delphine, Viengchareun, Say, Young, Jacques, Chasseloup, Fanny, and Annual Meeting of the Endocrine Society 2022

Abstract

CONTEXT : Primary bilateral macronodular adrenal hyperplasia (PBMAH) with glucose-dependent insulinotropic polypeptide (GIP)-dependent Cushing's syndrome is caused by ectopic expression of GIP receptor (GIPR) in the adrenal lesions. Such ectopic expression of GIPR was also reported in other endocrine neoplasm, notably in somatotroph pituitary adenomas from acromegalic patients with paradoxical increase of GH after oral glucose load, suggesting a common molecular pathogenesis. We aimed to identify the driver event responsible for GIP-dependent PBMAH with Cushing's syndrome and ectopic GIPR expression in somatotropinomas. [...]

Published
2022

8. OR04-4 Loss of KDM1A in Bilateral Macronodular Adrenal Hyperplasia With GIP-Dependent Cushing's Syndrome and in Acromegaly With Paradoxical GH Response to Oral Glucose

Author

Amazit, Larbi, Barbot, Mattia, Beau, Isabelle, Bouligand, Jérôme, Bourdeau, Isabelle, Chanson, Philippe, Cloix, Lucie, Corbeil, Gilles, de Herder, Wouter, Deméocq, Vianney, Desailloud, Rachel, Dumontet, Charles, Dupeux, Margot, Emy, Philippe, Fiore, Frederic, Guiochon-Mantel, Anne, Kamenicky, Peter, Lacroix, André, Ladurelle, Nataly, Lambert, Benoit, Lecoq, Anne-Lise, Lefebvre, Hervé, Maiter, Dominique, Pattou, Francois, Proust, Alexis, Regazzo, Daniela, Salenave, Sylvie, Scaroni, Carla, Scharfmann, Raphael, Tabarin, Antoine, Tachdjian, Gerard, Tetreault, Martine, Tosca, Lucie, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Vezzosi, Delphine, Viengchareun, Say, Young, Jacques, Chasseloup, Fanny, Annual Meeting of the Endocrine Society 2022, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, and UCL - (SLuc) Service d'endocrinologie et de nutrition

Subjects
Diabetes and Metabolism, Endocrinology, Endocrinology, Diabetes and Metabolism
Abstract

Context Primary bilateral macronodular adrenal hyperplasia (PBMAH) with glucose-dependent insulinotropic polypeptide (GIP)-dependent Cushing's syndrome is caused by ectopic expression of GIP receptor (GIPR) in the adrenal lesions. Such ectopic expression of GIPR was also reported in other endocrine neoplasm, notably in somatotroph pituitary adenomas from acromegalic patients with paradoxical increase of GH after oral glucose load, suggesting a common molecular pathogenesis. We aimed to identify the driver event responsible for GIP-dependent PBMAH with Cushing's syndrome and ectopic GIPR expression in somatotropinomas. Methods We conducted an international, multicenter, cohort study. We collected blood and adrenal samples from patients who had undergone unilateral or bilateral adrenalectomy for GIP-dependent PBMAH with Cushing's syndrome. Adrenal samples from patients with PBMAH and Cushing's syndrome without food-dependent cortisol production were used as controls. We further collected somatotropinoma specimens from acromegaly patients followed at two expert endocrine centers in France. Results 17 patients with familial or sporadic GIP-dependent PBMAH with Cushing's syndrome were studied. We identified germline heterozygous mutations in the lysine demethylase 1A (KDM1A) gene in all 17 patients. We further identified a recurrent deletion of the short arm of chromosome 1 harboring the KDM1A locus in the adrenal lesions of affected patients. None of the 25 patients in the control group had KDM1A germline or somatic alterations. Concomitant genetic inactivation of both KDM1A alleles resulted in loss of KDM1A expression in the adrenal lesions. RNA-sequencing revealed the global impact of KDM1A loss in adrenal tissue on gene transcription and identified differentially regulated genes including those encoding for GIPR and other G-Protein-Coupled Receptors that may be involved in adrenal tumorigenesis and regulation of steroidogenesis. In vitro pharmacologic inhibition, silencing and knock-out by CRISPR-Cas9 genome editing of KDM1A led to an increase in GIPR transcripts and protein in human adrenocortical H295R cells. Somatotropinoma samples from 78 patients with acromegaly were studied. 24% of these patients presented with a paradoxical rise of GH after oral glucose load and expressed ectopically GIP-receptor in their somatotropinoma. None of the somatotropinomas harbored KDM1A pathogenic variants, but those from patients with paradoxical GH response displayed a recurrent chromosome 1p loss. Discussion We identified germline inactivating KDM1A mutations and loss of heterozygosity as a genetic predisposition to GIP-dependent PBMAH with Cushing's syndrome following a tumor suppressor gene model of tumorigenesis. We currently perform genetic screening in first-degree relatives of patients with GIP-dependent PBMAH with Cushing's syndrome and clinical examination with biochemical testing in asymptomatic KDM1A variant carriers. We did not identify somatic KDM1A mutations in somatotropinomas expressing GIPR ectopically, however their recurrent 1p chromosome loss suggests that KDM1A haploinsufficiency may contribute to GIPR expression in those tumors. Presentation: Saturday, June 11, 2022 12:15 p.m. - 12:30 p.m.

Published
2022

9. Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study.

Author

UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - (SLuc) Service d'endocrinologie et de nutrition, Chasseloup, Fanny, Bourdeau, Isabelle, Tabarin, Antoine, Regazzo, Daniela, Dumontet, Charles, Ladurelle, Nataly, Tosca, Lucie, Amazit, Larbi, Proust, Alexis, Scharfmann, Raphael, Mignot, Tiphaine, Fiore, Frédéric, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Maiter, Dominique, Young, Jacques, Lecoq, Anne-Lise, Deméocq, Vianney, Salenave, Sylvie, Lefebvre, Hervé, Cloix, Lucie, Emy, Philippe, Dessailloud, Rachel, Vezzosi, Delphine, Scaroni, Carla, Barbot, Mattia, de Herder, Wouter, Pattou, François, Tétreault, Martine, Corbeil, Gilles, Dupeux, Margot, Lambert, Benoit, Tachdjian, Gérard, Guiochon-Mantel, Anne, Beau, Isabelle, Chanson, Philippe, Viengchareun, Say, Lacroix, André, Bouligand, Jérôme, Kamenický, Peter, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - (SLuc) Service d'endocrinologie et de nutrition, Chasseloup, Fanny, Bourdeau, Isabelle, Tabarin, Antoine, Regazzo, Daniela, Dumontet, Charles, Ladurelle, Nataly, Tosca, Lucie, Amazit, Larbi, Proust, Alexis, Scharfmann, Raphael, Mignot, Tiphaine, Fiore, Frédéric, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Maiter, Dominique, Young, Jacques, Lecoq, Anne-Lise, Deméocq, Vianney, Salenave, Sylvie, Lefebvre, Hervé, Cloix, Lucie, Emy, Philippe, Dessailloud, Rachel, Vezzosi, Delphine, Scaroni, Carla, Barbot, Mattia, de Herder, Wouter, Pattou, François, Tétreault, Martine, Corbeil, Gilles, Dupeux, Margot, Lambert, Benoit, Tachdjian, Gérard, Guiochon-Mantel, Anne, Beau, Isabelle, Chanson, Philippe, Viengchareun, Say, Lacroix, André, Bouligand, Jérôme, and Kamenický, Peter

Abstract

BACKGROUND: GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome is caused by aberrant expression of the GIP receptor in adrenal lesions. The bilateral nature of this disease suggests germline genetic predisposition. We aimed to identify the genetic driver event responsible for GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome. METHODS: We conducted a multicentre, retrospective, cohort study at endocrine hospitals and university hospitals in France, Canada, Italy, Greece, Belgium, and the Netherlands. We collected blood and adrenal samples from patients who had undergone unilateral or bilateral adrenalectomy for GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome. Adrenal samples from patients with primary bilateral macronodular adrenal hyperplasia who had undergone an adrenalectomy for overt or mild Cushing's syndrome without evidence of food-dependent cortisol production and those with GIP-dependent unilateral adrenocortical adenomas were used as control groups. We performed whole genome, whole exome, and targeted next generation sequencing, and copy number analyses of blood and adrenal DNA from patients with familial or sporadic disease. We performed RNA sequencing on adrenal samples and functional analyses of the identified genetic defect in the human adrenocortical cell line H295R. FINDINGS: 17 patients with GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome were studied. The median age of patients was 43·3 (95% CI 38·8-47·8) years and most patients (15 [88%]) were women. We identified germline heterozygous pathogenic or most likely pathogenic variants in the KDM1A gene in all 17 patients. We also identified a recurrent deletion in the short p arm of chromosome 1 harboring the KDM1A locus in adrenal lesions of these patients. None of the 29 patients in the control groups had KDM1A germline or somatic alterations.

Published
2021

12. Loss of KDM1Ain GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome: a multicentre, retrospective, cohort study

Author

Chasseloup, Fanny, Bourdeau, Isabelle, Tabarin, Antoine, Regazzo, Daniela, Dumontet, Charles, Ladurelle, Nataly, Tosca, Lucie, Amazit, Larbi, Proust, Alexis, Scharfmann, Raphael, Mignot, Tiphaine, Fiore, Frédéric, Tsagarakis, Stylianos, Vassiliadi, Dimitra, Maiter, Dominique, Young, Jacques, Lecoq, Anne-Lise, Deméocq, Vianney, Salenave, Sylvie, Lefebvre, Hervé, Cloix, Lucie, Emy, Philippe, Dessailloud, Rachel, Vezzosi, Delphine, Scaroni, Carla, Barbot, Mattia, de Herder, Wouter, Pattou, François, Tétreault, Martine, Corbeil, Gilles, Dupeux, Margot, Lambert, Benoit, Tachdjian, Gérard, Guiochon-Mantel, Anne, Beau, Isabelle, Chanson, Philippe, Viengchareun, Say, Lacroix, André, Bouligand, Jérôme, and Kamenický, Peter

Abstract

GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome is caused by aberrant expression of the GIP receptor in adrenal lesions. The bilateral nature of this disease suggests germline genetic predisposition. We aimed to identify the genetic driver event responsible for GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing's syndrome.

Published
2021
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13. Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016

Author

McCormack, Ann, primary, Dekkers, Olaf M, additional, Petersenn, Stephan, additional, Popovic, Vera, additional, Trouillas, Jacqueline, additional, Raverot, Gerald, additional, Burman, Pia, additional, _, _, additional, Hubalewska-Dydejezky, Alicia, additional, Assie, Guillaume, additional, Bach, Leon, additional, Batisse-Lignier, Marie, additional, Berinder, Katarina, additional, Bilbao, Ismene, additional, Bonnet, Fabrice, additional, Bresson, Damien, additional, Bruno, Oscar, additional, Campdera, Mariana, additional, Caron, Philippe, additional, Castinetti, Frederic, additional, Ceccato, Filippo, additional, Chabre, Olivier, additional, Chanson, Philippe, additional, Christ, Emanuel, additional, Cloix, Lucie, additional, Cortet, Christine, additional, Criniere, Lise, additional, Cuatrecasas, Guillem, additional, Debono, Miguel, additional, Delemer, Brigitte, additional, Desailloud, Rachel, additional, Deutschbein, Timo, additional, Dusek, Tina, additional, Engström, Britt Eden, additional, Faustini-Fustini, Marco, additional, Franck, Schillo, additional, Garcia, Cyril, additional, Greenman, Yona, additional, Gil, Susana Mallea, additional, Mantovani, Giovanna, additional, Gurnell, Mark, additional, Heaney, Anthony, additional, Henley, David, additional, Higham, Claire, additional, Hoving, EW, additional, Höybye, Charlotte, additional, Ichihara, Atsuhiro, additional, Jaffrain-Rea, Marie-Lise, additional, Johannsson, Gudmundur, additional, Jorgensen, Jens Otto Lunde, additional, Jublanc, Christel, additional, Komor, Jan, additional, Korbonits, Marta, additional, Kralievic, Ivana, additional, Larrieu-Ciron, Delphine, additional, Lasolle, Helene, additional, Laws, Edward, additional, Losa, Marco, additional, Maiter, Dominique, additional, Marcocci, Claudio, additional, Marques, Olinda Castro, additional, Mazzuco, Tania Longo, additional, Micko, Alexander, additional, Bourcigaux, Nathalie, additional, Neggers, Sebastian, additional, Newell-Price, John, additional, Perez-Berida, Belén, additional, Ortiz, Leon D, additional, Ragnarsson, Oskar, additional, Ragonese, Marta, additional, Reincke, Martin, additional, Sadoul, Jean-Louis, additional, Shimatsu, Akira, additional, Syro, Luis V, additional, Taillandier, Luc, additional, Toth, Miklos, additional, Usui, Takeshi, additional, Valkusz, Zauzsanna, additional, Vila, Greisa, additional, Whitelaw, Ben, additional, and Zatelli, Maria Chiara, additional

Published
2018
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15. Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas

Author

Lasolle, Hélène, primary, Cortet, Christine, additional, Castinetti, Fréderic, additional, Cloix, Lucie, additional, Caron, Philippe, additional, Delemer, Brigitte, additional, Desailloud, Rachel, additional, Jublanc, Christel, additional, Lebrun-Frenay, Christine, additional, Sadoul, Jean-Louis, additional, Taillandier, Luc, additional, Batisse-Lignier, Marie, additional, Bonnet, Fabrice, additional, Bourcigaux, Nathalie, additional, Bresson, Damien, additional, Chabre, Olivier, additional, Chanson, Philippe, additional, Garcia, Cyril, additional, Haissaguerre, Magalie, additional, Reznik, Yves, additional, Borot, Sophie, additional, Villa, Chiara, additional, Vasiljevic, Alexandre, additional, Gaillard, Stephan, additional, Jouanneau, Emmanuel, additional, Assié, Guillaume, additional, and Raverot, Gérald, additional

Published
2017
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16. La vistafine est exprimée par les cellules de la granulosa humaine : Régulation par la metformine via la voie AMPK/SIRT1 et rôle dans la stéroïdogenèse ?

Author

Reverchon, Maxime, Cornuau, Marion, Rame, Christelle, Cloix, Lucie, Royère, Dominique, Guerif, Fabrice, Dupont, Joëlle, ProdInra, Migration, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Service de Médecine et Biologie de la Reproduction, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Association pour le Développement des Biotechnologies en Région Centre (Biotechnocentre). Tours, FRA., Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), and Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS)

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2012

17. Caractérisation et rôle de l'omentine dans les cellules de la granulosa humaine ?

Author

Cloix, Lucie, Reverchon, Maxime, Rame, Christelle, Cornuau, Marion, Royère, Dominique, Guerif, Fabrice, Dupont, Joëlle, ProdInra, Migration, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Service de Médecine et Biologie de la Reproduction, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Association pour le Développement des Biotechnologies en Région Centre (Biotechnocentre). Tours, FRA., Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), and Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS)

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2012

18. Mass spectrometry for steroid assays

Author

Dufour-Rainfray, Diane, additional, Moal, Valérie, additional, Cloix, Lucie, additional, Mathieu, Elisabeth, additional, Gauchez, Anne-Sophie, additional, Brossaud, Julie, additional, Corcuff, Jean-Benoît, additional, Fraissinet, François, additional, Collet, Christine, additional, Boux de Casson, Florence, additional, Guilloteau, Denis, additional, Emond, Patrick, additional, and Reynier, Pascal, additional

Published
2015
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19. High genetic variation of the multidrug transporter gene cmeB in Campylobacter jejuni and Campylobacter coli

Author

Cagliero, Cedric, Cloix, Lucie, Payot, Sophie, Cloeckaert, Axel, Bio-Agresseurs, Santé, Environnement [Nouzilly] (UR BASE), Institut National de la Recherche Agronomique (INRA), ProdInra, Archive Ouverte, and Unité de recherche Bio-Agresseurs, Santé, Environnement (BASE)

Subjects
[SDV] Life Sciences [q-bio], kjeldahl method, bactérie, pcr, [SDV]Life Sciences [q-bio], campylobacter coli, technique analytique, TRANSPORTEUR, bacterium, enzyme de restriction, restriction enzymes, campylobacter jejuni
Abstract

High genetic variation of the multidrug transporter gene cmeB in Campylobacter jejuni and Campylobacter coli. 6. European Congress of Chemotherapy and Infection - 24 Réunion Interdisciplinaire de Chimiothérapie Anti-Infectieuse

Published
2004

20. Expression and Regulation of INTELECTIN1 in Human Granulosa-Lutein Cells: Role in IGF-1-Induced Steroidogenesis Through NAMPT1

Author

Cloix, Lucie, primary, Reverchon, Maxime, additional, Cornuau, Marion, additional, Froment, Pascal, additional, Ramé, Christelle, additional, Costa, Caroline, additional, Froment, Gisèle, additional, Lecomte, Pierre, additional, Chen, Wenyong, additional, Royère, Dominique, additional, Guerif, Fabrice, additional, and Dupont, Joëlle, additional

Published
2014
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22. Treatment of aggressive pituitary tumours and carcinomas: Results of a European Society of Endocrinology (ESE) survey 2016

Author

Ann McCormack, Olaf M Dekkers, Stephan Petersenn, Vera Popovic, Jacqueline Trouillas, Gerald Raverot, Pia Burman, Alicia Hubalewska-Dydejezky, Guillaume Assie, Leon Bach, Marie Batisse-Lignier, Katarina Berinder, Ismene Bilbao, Fabrice Bonnet, Damien Bresson, Oscar Bruno, Mariana Campdera, Philippe Caron, Frederic Castinetti, Filippo Ceccato, Olivier Chabre, Philippe Chanson, Emanuel Christ, Lucie Cloix, Christine Cortet, Lise Criniere, Guillem Cuatrecasas, Miguel Debono, Brigitte Delemer, Rachel Desailloud, Timo Deutschbein, Tina Dusek, Britt Eden Engström, Marco Faustini-Fustini, Schillo Franck, Cyril Garcia, Yona Greenman, Susana Mallea Gil, Giovanna Mantovani, Mark Gurnell, Anthony Heaney, David Henley, Claire Higham, EW Hoving, Charlotte Höybye, Atsuhiro Ichihara, Marie-Lise Jaffrain-Rea, Gudmundur Johannsson, Jens Otto Lunde Jorgensen, Christel Jublanc, Jan Komor, Marta Korbonits, Ivana Kralievic, Delphine Larrieu-Ciron, Helene Lasolle, Edward Laws, Marco Losa, Dominique Maiter, Claudio Marcocci, Olinda Castro Marques, Tania Longo Mazzuco, Alexander Micko, Nathalie Bourcigaux, Sebastian Neggers, John Newell-Price, Belén Perez-Berida, Leon D Ortiz, Oskar Ragnarsson, Marta Ragonese, Martin Reincke, Jean-Louis Sadoul, Akira Shimatsu, Luis V Syro, Luc Taillandier, Miklos Toth, Takeshi Usui, Zauzsanna Valkusz, Greisa Vila, Ben Whitelaw, Maria Chiara Zatelli, Mccormack, Ann, Dekkers, Olaf M, Petersenn, Stephan, Popovic, Vera, Trouillas, Jacqueline, Raverot, Gerald, Burman, Pia, Harrison, Alex, Hubalewska-Dydejezky, Alicia, Assie, Guillaume, Bach, Leon, Batisse-Lignier, Marie, Berinder, Katarina, Bilbao, Ismene, Bonnet, Fabrice, Bresson, Damien, Bruno, Oscar, Campdera, Mariana, Caron, Philippe, Castinetti, Frederic, Ceccato, Filippo, Chabre, Olivier, Chanson, Philippe, Christ, Emanuel, Cloix, Lucie, Cortet, Christine, Criniere, Lise, Cuatrecasas, Guillem, Debono, Miguel, Delemer, Brigitte, Desailloud, Rachel, Deutschbein, Timo, Dusek, Tina, Engström, Britt Eden, Faustini-Fustini, Marco, Franck, Schillo, Garcia, Cyril, Greenman, Yona, Gil, Susana Mallea, Mantovani, Giovanna, Gurnell, Mark, Heaney, Anthony, Henley, David, Higham, Claire, Hoving, E. W., Höybye, Charlotte, Ichihara, Atsuhiro, Jaffrain-Rea, Marie-Lise, Johannsson, Gudmundur, Jorgensen, Jens Otto Lunde, Jublanc, Christel, Komor, Jan, Korbonits, Marta, Kralievic, Ivana, Larrieu-Ciron, Delphine, Lasolle, Helene, Laws, Edward, Losa, Marco, Maiter, Dominique, Marcocci, Claudio, Marques, Olinda Castro, Mazzuco, Tania Longo, Micko, Alexander, Bourcigaux, Nathalie, Neggers, Sebastian, Newell-Price, John, Perez-Berida, Belén, Ortiz, Leon D, Ragnarsson, Oskar, Ragonese, Marta, Reincke, Martin, Sadoul, Jean-Loui, Shimatsu, Akira, Syro, Luis V, Taillandier, Luc, Toth, Miklo, Usui, Takeshi, Valkusz, Zauzsanna, Vila, Greisa, Whitelaw, Ben, and Zatelli, Maria Chiara

Subjects
Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Medizin, pituitary carcinoma, Pituitary neoplasm, Neurosurgical Procedure, Neurosurgical Procedures, 0302 clinical medicine, Endocrinology, Pituitary tumour, aggressive pituitary tumour, pituitary carcinoma, temozolomide, Surveys and Questionnaires, Antineoplastic Combined Chemotherapy Protocols, Surveys and Questionnaire, Pituitary Neoplasm, Adenoma, Adolescent, Adult, Aged, Antineoplastic Agents, Alkylating, Bevacizumab, Capecitabine, Carcinoma, Carmustine, Child, Child, Preschool, DNA Modification Methylases, DNA Repair Enzymes, Dacarbazine, Europe, Female, Humans, Ki-67 Antigen, Middle Aged, Neoplasm Invasiveness, Pituitary Neoplasms, Societies, Medical, Temozolomide, Thalidomide, Tumor Suppressor Proteins, Young Adult, Cranial Irradiation, DNA Repair Enzyme, General Medicine, Alkylating, aggressive pituitary tumour, 3. Good health, Diabetes and Metabolism, 030220 oncology & carcinogenesis, Human, medicine.drug, medicine.medical_specialty, 030209 endocrinology & metabolism, Antineoplastic Agents, 03 medical and health sciences, Internal medicine, Medical, DNA Modification Methylase, medicine, Preschool, Neoplasm Invasivene, Tumor Suppressor Protein, Chemotherapy, Antineoplastic Combined Chemotherapy Protocol, Pituitary tumour, business.industry, medicine.disease, Concomitant, business, Societies, Progressive disease
Abstract

Objective To collect outcome data in a large cohort of patients with aggressive pituitary tumours (APT)/carcinomas (PC) and specifically report effects of temozolomide (TMZ) treatment. Design Electronic survey to ESE members Dec 2015–Nov 2016. Results Reports on 166 patients (40 PC, 125 APT, 1 unclassified) were obtained. Median age at diagnosis was 43 (range 4–79) years. 69% of the tumours were clinically functioning, and the most frequent immunohistochemical subtype were corticotroph tumours (45%). Ki-67 index did not distinguish APT from PC, median 7% and 10% respectively. TMZ was first-line chemotherapy in 157 patients. At the end of the treatment (median 9 cycles), radiological evaluation showed complete response (CR) in 6%, partial response (PR) in 31%, stable disease (SD) in 33% and progressive disease in 30%. Response was more frequent in patients receiving concomitant radiotherapy and TMZ. CR was seen only in patients with low MGMT expression. Clinically functioning tumours were more likely to respond than non-functioning tumours, independent of MGMT status. Of patients with CR, PR and SD, 25, 40 and 48% respectively progressed after a median of 12-month follow-up. Other oncological drugs given as primary treatment and to TMZ failures resulted in PR in 20%. Conclusion This survey confirms that TMZ is established as first-line chemotherapeutic treatment of APT/PC. Clinically functioning tumours, low MGMT and concurrent radiotherapy were associated with a better response. The limited long-term effect of TMZ and the poor efficacy of other drugs highlight the need to identify additional effective therapies.

Published
2018

23. 30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

Author

Singhal R, Ludwig C, Rudge G, Gkoutos GV, Tahrani A, Mahawar K, Pędziwiatr M, Major P, Zarzycki P, Pantelis A, Lapatsanis DP, Stravodimos G, Matthys C, Focquet M, Vleeschouwers W, Spaventa AG, Zerrweck C, Vitiello A, Berardi G, Musella M, Sanchez-Meza A, Cantu FJ Jr, Mora F, Cantu MA, Katakwar A, Reddy DN, Elmaleh H, Hassan M, Elghandour A, Elbanna M, Osman A, Khan A, Layani L, Kiran N, Velikorechin A, Solovyeva M, Melali H, Shahabi S, Agrawal A, Shrivastava A, Sharma A, Narwaria B, Narwaria M, Raziel A, Sakran N, Susmallian S, Karagöz L, Akbaba M, Pişkin SZ, Balta AZ, Senol Z, Manno E, Iovino MG, Osman A, Qassem M, Arana-Garza S, Povoas HP, Vilas-Boas ML, Naumann D, Super J, Li A, Ammori BJ, Balamoun H, Salman M, Nasta AM, Goel R, Sánchez-Aguilar H, Herrera MF, Abou-Mrad A, Cloix L, Mazzini GS, Kristem L, Lazaro A, Campos J, Bernardo J, González J, Trindade C, Viveiros O, Ribeiro R, Goitein D, Hazzan D, Segev L, Beck T, Reyes H, Monterrubio J, García P, Benois M, Kassir R, Contine A, Elshafei M, Aktas S, Weiner S, Heidsieck T, Level L, Pinango S, Ortega PM, Moncada R, Valenti V, Vlahović I, Boras Z, Liagre A, Martini F, Juglard G, Motwani M, Saggu SS, Al Moman H, López LAA, Cortez MAC, Zavala RA, D'Haese C, Kempeneers I, Himpens J, Lazzati A, Paolino L, Bathaei S, Bedirli A, Yavuz A, Büyükkasap Ç, Özaydın S, Kwiatkowski A, Bartosiak K, Walędziak M, Santonicola A, Angrisani L, Iovino P, Palma R, Iossa A, Boru CE, De Angelis F, Silecchia G, Hussain A, Balchandra S, Coltell IB, Pérez JL, Bohra A, Awan AK, Madhok B, Leeder PC, Awad S, Al-Khyatt W, Shoma A, Elghadban H, Ghareeb S, Mathews B, Kurian M, Larentzakis A, Vrakopoulou GZ, Albanopoulos K, Bozdag A, Lale A, Kirkil C, Dincer M, Bashir A, Haddad A, Hijleh LA, Zilberstein B, de Marchi DD, Souza WP, Brodén CM, Gislason H, Shah K, Ambrosi A, Pavone G, Tartaglia N, Kona SLK, Kalyan K, Perez CEG, Botero MAF, Covic A, Timofte D, Maxim M, Faraj D, Tseng L, Liem R, Ören G, Dilektasli E, Yalcin I, AlMukhtar H, Al Hadad M, Mohan R, Arora N, Bedi D, Rives-Lange C, Chevallier JM, Poghosyan T, Sebbag H, Zinaï L, Khaldi S, Mauchien C, Mazza D, Dinescu G, Rea B, Pérez-Galaz F, Zavala L, Besa A, Curell A, Balibrea JM, Vaz C, Galindo L, Silva N, Caballero JLE, Sebastian SO, Marchesini JCD, da Fonseca Pereira RA, Sobottka WH, Fiolo FE, Turchi M, Coelho ACJ, Zacaron AL, Barbosa A, Quinino R, Menaldi G, Paleari N, Martinez-Duartez P, de Aragon Ramírez de Esparza GM, Esteban VS, Torres A, Garcia-Galocha JL, Josa M, Pacheco-Garcia JM, Mayo-Ossorio MA, Chowbey P, Soni V, de Vasconcelos Cunha HA, Castilho MV, Ferreira RMA, Barreiro TA, Charalabopoulos A, Sdralis E, Davakis S, Bomans B, Dapri G, Van Belle K, Takieddine M, Vaneukem P, Karaca ESA, Karaca FC, Sumer A, Peksen C, Savas OA, Chousleb E, Elmokayed F, Fakhereldin I, Aboshanab HM, Swelium T, Gudal A, Gamloo L, Ugale A, Ugale S, Boeker C, Reetz C, Hakami IA, Mall J, Alexandrou A, Baili E, Bodnar Z, Maleckas A, Gudaityte R, Guldogan CE, Gundogdu E, Ozmen MM, Thakkar D, Dukkipati N, Shah PS, Shah SS, Shah SS, Adil MT, Jambulingam P, Mamidanna R, Whitelaw D, Adil MT, Jain V, Veetil DK, Wadhawan R, Torres A, Torres M, Tinoco T, Leclercq W, Romeijn M, van de Pas K, Alkhazraji AK, Taha SA, Ustun M, Yigit T, Inam A, Burhanulhaq M, Pazouki A, Eghbali F, Kermansaravi M, Jazi AHD, Mahmoudieh M, Mogharehabed N, Tsiotos G, Stamou K, Barrera Rodriguez FJ, Rojas Navarro MA, Torres OM, Martinez SL, Tamez ERM, Millan Cornejo GA, Flores JEG, Mohammed DA, Elfawal MH, Shabbir A, Guowei K, So JB, Kaplan ET, Kaplan M, Kaplan T, Pham D, Rana G, Kappus M, Gadani R, Kahitan M, Pokharel K, Osborne A, Pournaras D, Hewes J, Napolitano E, Chiappetta S, Bottino V, Dorado E, Schoettler A, Gaertner D, Fedtke K, Aguilar-Espinosa F, Aceves-Lozano S, Balani A, Nagliati C, Pennisi D, Rizzi A, Frattini F, Foschi D, Benuzzi L, Parikh C, Shah H, Pinotti E, Montuori M, Borrelli V, Dargent J, Copaescu CA, Hutopila I, Smeu B, Witteman B, Hazebroek E, Deden L, Heusschen L, Okkema S, Aufenacker T, den Hengst W, Vening W, van der Burgh Y, Ghazal A, Ibrahim H, Niazi M, Alkhaffaf B, Altarawni M, Cesana GC, Anselmino M, Uccelli M, Olmi S, Stier C, Akmanlar T, Sonnenberg T, Schieferbein U, Marcolini A, Awruch D, Vicentin M, de Souza Bastos EL, Gregorio SA, Ahuja A, Mittal T, Bolckmans R, Wiggins T, Baratte C, Wisnewsky JA, Genser L, Chong L, Taylor L, Ward S, Chong L, Taylor L, Hi MW, Heneghan H, Fearon N, Plamper A, Rheinwalt K, Heneghan H, Geoghegan J, Ng KC, Fearon N, Kaseja K, Kotowski M, Samarkandy TA, Leyva-Alvizo A, Corzo-Culebro L, Wang C, Yang W, Dong Z, Riera M, Jain R, Hamed H, Said M, Zarzar K, Garcia M, Türkçapar AG, Şen O, Baldini E, Conti L, Wietzycoski C, Lopes E, Pintar T, Salobir J, Aydin C, Atici SD, Ergin A, Ciyiltepe H, Bozkurt MA, Kizilkaya MC, Onalan NBD, Zuber MNBA, Wong WJ, Garcia A, Vidal L, Beisani M, Pasquier J, Vilallonga R, Sharma S, Parmar C, Lee L, Sufi P, Sinan H, and Saydam M

Subjects
COVID-19 Testing, Cohort Studies, Humans, Incidence, Pandemics, Postoperative Complications epidemiology, SARS-CoV-2, Bariatric Surgery, COVID-19, Diabetes Mellitus, Type 2, Obesity, Morbid surgery
Abstract

Background: There are data on the safety of cancer surgery and the efficacy of preventive strategies on the prevention of postoperative symptomatic COVID-19 in these patients. But there is little such data for any elective surgery. The main objectives of this study were to examine the safety of bariatric surgery (BS) during the coronavirus disease 2019 (COVID-19) pandemic and to determine the efficacy of perioperative COVID-19 protective strategies on postoperative symptomatic COVID-19 rates., Methods: We conducted an international cohort study to determine all-cause and COVID-19-specific 30-day morbidity and mortality of BS performed between 01/05/2020 and 31/10/2020., Results: Four hundred ninety-nine surgeons from 185 centres in 42 countries provided data on 7704 patients. Elective primary BS (n = 7084) was associated with a 30-day morbidity of 6.76% (n = 479) and a 30-day mortality of 0.14% (n = 10). Emergency BS, revisional BS, insulin-treated type 2 diabetes, and untreated obstructive sleep apnoea were associated with increased complications on multivariable analysis. Forty-three patients developed symptomatic COVID-19 postoperatively, with a higher risk in non-whites. Preoperative self-isolation, preoperative testing for SARS-CoV-2, and surgery in institutions not concurrently treating COVID-19 patients did not reduce the incidence of postoperative COVID-19. Postoperative symptomatic COVID-19 was more likely if the surgery was performed during a COVID-19 peak in that country., Conclusions: BS can be performed safely during the COVID-19 pandemic with appropriate perioperative protocols. There was no relationship between preoperative testing for COVID-19 and self-isolation with symptomatic postoperative COVID-19. The risk of postoperative COVID-19 risk was greater in non-whites or if BS was performed during a local peak., (© 2021. The Author(s).)

Published
2021
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