12 results on '"Clerc, O F"'
Search Results
2. 1172 Predictive value of coronary artery calcium score for myocardial ischaemia in positron emission tomography
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Clerc, O F, primary, Caobelli, F, additional, Haaf, P, additional, and Zellweger, M J, additional
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- 2020
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3. P3187Meta-analysis of coronary CT angiography for risk stratification in asymptomatic diabetic patients
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Clerc, O F, primary, Haaf, P, additional, and Zellweger, M J, additional
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- 2018
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4. 1426Meta-analysis of SPECT-MPI for risk stratification in asymptomatic diabetic patients
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Clerc, O F, primary, Haaf, P, additional, and Zellweger, M J, additional
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- 2018
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- View/download PDF
5. Poster Session 2 : Monday 4 May 2015, 08
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Bouyoucef, S E, Uusitalo, V, Kamperidis, V, De Graaf, M A, Maaniitty, T, Stenstrom, I, Broersen, A, Scholte, A J, Saraste, A, Bax, J J, Knuuti, J, Furuhashi, T, Moroi, M, Awaya, T, Masai, H, Minakawa, M, Kunimasa, T, Fukuda, H, Sugi, K, Berezin, A, Kremzer, A, Clerc, O F, Kaufmann, B, Possner, M, Liga, R, Vontobel, J, Mikulicic, F, Graeni, C, Benz, D C, Kaufmann, P A, Buechel, R B, Ferreira, Mjv, Cunha, M J, Albuquerque, A, Ramos, D, Costa, G, Lima, J, Pego, M, Peix, A, Cisneros, L, Cabrera, L O, Padron, K, Rodriguez, L, Heres, F, Carrillo, R, Mena, E, Fernandez, Y, Huizing, E D, Van Dijk, J D, Van Dalen, J A, Timmer, J R, Ottervanger, J P, Slump, C H, Jager, P L, Venuraju, S, Jeevarethinam, A, Yerramasu, A, Atwal, S, Mehta, V S, Lahiri, A, Arjonilla Lopez, A, Calero Rueda, M J, Gallardo, G, Fernandez-Cuadrado, J, Hernandez Aceituno, D, Sanchez Hernandez, J, Yoshida, H, Mizukami, A, Matsumura, A, Smettei, O, Abazid, R, Sayed, S, Mlynarska, A, Mlynarski, R, Golba, K, Sosnowski, M, Winther, S, Svensson, M, Jorgensen, H S, Bouchelouche, K, Gormsen, L C, Holm, N R, Botker, H E, Ivarsen, P R, Bottcher, M, Cortes, C M, Aramayo G, E N, Daicz, M, Casuscelli, J F, Alaguibe, E D, Neira Sepulveda, A, Cerda, M, Ganum, G E, Embon, M, Vigne, J, Enilorac, B, Lebasnier, A, Valancogne, L, Peyronnet, D, Manrique, A, Agostini, D, Menendez, D, Rajpal, S, Kocherla, C, Acharya, M, Reddy, P, Sazonova, I, Ilushenkova, Yun, Batalov, R E, Rogovskaya, Y V, Lishmanov, Y B, Popov, S V, Varlamova, N V, Prado Diaz, S, Jimenez Rubio, C, Gemma, D, Refoyo Salicio, E, Valbuena Lopez, S C, Moreno Yanguela, M, Torres, M, Fernandez-Velilla, M, Lopez-Sendon, J L, Guzman Martinez, G, Puente, A, Rosales, S, Martinez, C, Cabada, M, Melendez, G M, Ferreira, R, Gonzaga, A, Santos, J, Vijayan, S, Smith, Smg, Smith, M, Muthusamy, R, Takeishi, Y, Oikawa, M, Goral, J L, Napoli, J, Montana, O R, Damico, A C, Quiroz, M C, Damico, A E, Forcada, P J, Schmidberg, J M, Zucchiatti, N E, Olivieri, D B, Dumo, A, Ruano, S, Rakhit, R, Davar, J, Nair, D, Cohen, M, Darko, D, Yokota, S, Maas, Ahe, Mouden, M, Knollema, S, Sanja Mazic, S M, Lazovic, B, Marina Djelic, Mdj, Jelena Suzic Lazic, J S, Tijana Acimovic, T A, Milica Deleva, M D, Vesnina, Z H, Zafrir, N, Bental, T, Mats, I, Solodky, A, Gutstein, A, Hasid, Y, Belzer, D, Kornowski, R, Ben Said, Rim, Ben Mansour, N, Ibn Haj Amor, H, Chourabi, C, Hagui, A, Fehri, W, Hawala, H, Shugushev, Z, Patrikeev, A, Maximkin, D, Chepurnoy, A, Kallianpur, V, Mambetov, A, Dokshokov, G, Teresinska, A, Wozniak, O, Maciag, A, Wnuk, J, Dabrowski, A, Czerwiec, A, Jezierski, J, Biernacka, K, Robinson, J, Prosser, J, Cheung, Gsm, Allan, S, Mcmaster, G, Reid, S, Tarbuck, A, Martin, W, Queiroz, R C, Falcao, A, Giorgi, McP, Imada, R, Nogueira, S A, Chalela, W A, Kalil Filho, R, Meneghetti, W A, Matveev, V V, Bubyenov, A S, Podzolkov, V I, Baranovich, V, Faibushevich, A, Kolzhecova, Y, Volkova, O, Fernandez, J, Lopez, G, Dondi, M, Paez, D, Butcher, Cjt, Reyes, E, Al-Housni, M B, Green, R, Santiago, H, Ghiotto, F, Hinton-Taylor, S, Pottle, A, Mason, M, Underwood, S R, Casans Tormo, I, Diaz-Exposito, R, Plancha-Burguera, E, Elsaban, K, Alsakhri, Hijji, Yoshinaga, K, Ochi, N, Tomiyama, Y, Katoh, C, Inoue, M, Nishida, M, Suzuki, E, Manabe, O, Ito, Y M, Tamaki, N, Tahilyani, A, Jafary, Fahim, Ho Hee Hwa, H H, Ozdemir, S, Kirilmaz, B, Barutcu, A, Tan, Y Z, Celik, F, Sakgoz, S, Cabada Gamboa, M, Puente Barragan, A, Morales Vitorino, N, Medina Servin, M A, Hindorf, C, Akil, S, Hedeer, F, Jogi, J, Engblom, H, Martire, V D, Pis Diez, E R, Martire, M V, Portillo, D O, Hoff, C M, Balche, A, Majgaard, J, Tolbod, L P, Harms, H J, Soerensen, J, Froekiaer, J, Nudi, F, Neri, G, Procaccini, E, Pinto, A, Vetere, M, Biondi-Zoccai, G, Soares, J, Do Val, R, Oliveira, M A, Meneghetti, J C, Tekabe, Y, Anthony, T, Li, Q, Schmidt, A M, Johnson, L, Groenman, M, Tarkia, M, Kakela, M, Halonen, P, Kiviniemi, T, Pietila, M, Yla-Herttuala, S, Roivainen, A, Nekolla, S, Swirzek, S, Higuchi, T, Reder, S, Schachoff, S, Bschorner, M, Laitinen, I, Robinson, S, Yousefi, B, Schwaiger, M, Kero, Tanja, Lindsjo, L, Antoni, Gunnar, Westermark, P, Carlson, K, Wikstrom, G, Sörensen, Jens, Lubberink, Mark, Rouzet, F, Cognet, T, Guedj, K, Morvan, M, El Shoukr, F, Louedec, L, Choqueux, C, Nicoletti, A, Le Guludec, D, Jimenez-Heffernan, A, Munoz-Beamud, F, Sanchez De Mora, E, Borrachero, C, Salgado, C, Ramos-Font, C, Lopez-Martin, J, Hidalgo, M L, Lopez-Aguilar, R, Soriano, E, Okizaki, A, Nakayama, M, Ishitoya, S, Sato, J, Takahashi, K, Burchert, I, Caobelli, F, Wollenweber, T, Nierada, M, Fulsche, J, Dieckmann, C, Bengel, F M, Shuaib, S, Mahlum, D, Port, S, Refoyo, E, Cuesta, E, Guzman, G, Lopez, T, Valbuena, S, Del Prado, S, Moreno, M, Harbinson, M, Donnelly, L, Einstein, A J, Johnson, L L, Deluca, A J, Kontak, A C, Groves, D W, Stant, J, Pozniakoff, T, Cheng, B, Rabbani, L E, Bokhari, S, Schuetze, C, Aguade-Bruix, S, Pizzi, M N, Romero-Farina, G, Terricabras, M, Villasboas, D, Castell-Conesa, J, Candell-Riera, J, Brunner, S, Gross, L, Todica, A, Lehner, S, Di Palo, A, Niccoli Asabella, A, Magarelli, C, Notaristefano, A, Ferrari, C, Rubini, G, Sellem, A, Melki, S, Elajmi, W, Hammami, H, Ziadi, M C, Montero, J, Ameriso, J L, Villavicencio, R L, Benito Gonzalez, T F, Mayorga Bajo, A, Gutierrez Caro, R, Rodriguez Santamarta, M, Alvarez Roy, L, Martinez Paz, E, Barinaga Martin, C, Martin Fernandez, J, Alonso Rodriguez, D, Iglesias Garriz, I, Rosillo, S, Taleb, S, Cherkaoui Salhi, G, Regbaoui, Y, Ait Idir, M, Guensi, A, Martin Lopez, C E, Castano Ruiz, M, Bouyoucef, S E, Uusitalo, V, Kamperidis, V, De Graaf, M A, Maaniitty, T, Stenstrom, I, Broersen, A, Scholte, A J, Saraste, A, Bax, J J, Knuuti, J, Furuhashi, T, Moroi, M, Awaya, T, Masai, H, Minakawa, M, Kunimasa, T, Fukuda, H, Sugi, K, Berezin, A, Kremzer, A, Clerc, O F, Kaufmann, B, Possner, M, Liga, R, Vontobel, J, Mikulicic, F, Graeni, C, Benz, D C, Kaufmann, P A, Buechel, R B, Ferreira, Mjv, Cunha, M J, Albuquerque, A, Ramos, D, Costa, G, Lima, J, Pego, M, Peix, A, Cisneros, L, Cabrera, L O, Padron, K, Rodriguez, L, Heres, F, Carrillo, R, Mena, E, Fernandez, Y, Huizing, E D, Van Dijk, J D, Van Dalen, J A, Timmer, J R, Ottervanger, J P, Slump, C H, Jager, P L, Venuraju, S, Jeevarethinam, A, Yerramasu, A, Atwal, S, Mehta, V S, Lahiri, A, Arjonilla Lopez, A, Calero Rueda, M J, Gallardo, G, Fernandez-Cuadrado, J, Hernandez Aceituno, D, Sanchez Hernandez, J, Yoshida, H, Mizukami, A, Matsumura, A, Smettei, O, Abazid, R, Sayed, S, Mlynarska, A, Mlynarski, R, Golba, K, Sosnowski, M, Winther, S, Svensson, M, Jorgensen, H S, Bouchelouche, K, Gormsen, L C, Holm, N R, Botker, H E, Ivarsen, P R, Bottcher, M, Cortes, C M, Aramayo G, E N, Daicz, M, Casuscelli, J F, Alaguibe, E D, Neira Sepulveda, A, Cerda, M, Ganum, G E, Embon, M, Vigne, J, Enilorac, B, Lebasnier, A, Valancogne, L, Peyronnet, D, Manrique, A, Agostini, D, Menendez, D, Rajpal, S, Kocherla, C, Acharya, M, Reddy, P, Sazonova, I, Ilushenkova, Yun, Batalov, R E, Rogovskaya, Y V, Lishmanov, Y B, Popov, S V, Varlamova, N V, Prado Diaz, S, Jimenez Rubio, C, Gemma, D, Refoyo Salicio, E, Valbuena Lopez, S C, Moreno Yanguela, M, Torres, M, Fernandez-Velilla, M, Lopez-Sendon, J L, Guzman Martinez, G, Puente, A, Rosales, S, Martinez, C, Cabada, M, Melendez, G M, Ferreira, R, Gonzaga, A, Santos, J, Vijayan, S, Smith, Smg, Smith, M, Muthusamy, R, Takeishi, Y, Oikawa, M, Goral, J L, Napoli, J, Montana, O R, Damico, A C, Quiroz, M C, Damico, A E, Forcada, P J, Schmidberg, J M, Zucchiatti, N E, Olivieri, D B, Dumo, A, Ruano, S, Rakhit, R, Davar, J, Nair, D, Cohen, M, Darko, D, Yokota, S, Maas, Ahe, Mouden, M, Knollema, S, Sanja Mazic, S M, Lazovic, B, Marina Djelic, Mdj, Jelena Suzic Lazic, J S, Tijana Acimovic, T A, Milica Deleva, M D, Vesnina, Z H, Zafrir, N, Bental, T, Mats, I, Solodky, A, Gutstein, A, Hasid, Y, Belzer, D, Kornowski, R, Ben Said, Rim, Ben Mansour, N, Ibn Haj Amor, H, Chourabi, C, Hagui, A, Fehri, W, Hawala, H, Shugushev, Z, Patrikeev, A, Maximkin, D, Chepurnoy, A, Kallianpur, V, Mambetov, A, Dokshokov, G, Teresinska, A, Wozniak, O, Maciag, A, Wnuk, J, Dabrowski, A, Czerwiec, A, Jezierski, J, Biernacka, K, Robinson, J, Prosser, J, Cheung, Gsm, Allan, S, Mcmaster, G, Reid, S, Tarbuck, A, Martin, W, Queiroz, R C, Falcao, A, Giorgi, McP, Imada, R, Nogueira, S A, Chalela, W A, Kalil Filho, R, Meneghetti, W A, Matveev, V V, Bubyenov, A S, Podzolkov, V I, Baranovich, V, Faibushevich, A, Kolzhecova, Y, Volkova, O, Fernandez, J, Lopez, G, Dondi, M, Paez, D, Butcher, Cjt, Reyes, E, Al-Housni, M B, Green, R, Santiago, H, Ghiotto, F, Hinton-Taylor, S, Pottle, A, Mason, M, Underwood, S R, Casans Tormo, I, Diaz-Exposito, R, Plancha-Burguera, E, Elsaban, K, Alsakhri, Hijji, Yoshinaga, K, Ochi, N, Tomiyama, Y, Katoh, C, Inoue, M, Nishida, M, Suzuki, E, Manabe, O, Ito, Y M, Tamaki, N, Tahilyani, A, Jafary, Fahim, Ho Hee Hwa, H H, Ozdemir, S, Kirilmaz, B, Barutcu, A, Tan, Y Z, Celik, F, Sakgoz, S, Cabada Gamboa, M, Puente Barragan, A, Morales Vitorino, N, Medina Servin, M A, Hindorf, C, Akil, S, Hedeer, F, Jogi, J, Engblom, H, Martire, V D, Pis Diez, E R, Martire, M V, Portillo, D O, Hoff, C M, Balche, A, Majgaard, J, Tolbod, L P, Harms, H J, Soerensen, J, Froekiaer, J, Nudi, F, Neri, G, Procaccini, E, Pinto, A, Vetere, M, Biondi-Zoccai, G, Soares, J, Do Val, R, Oliveira, M A, Meneghetti, J C, Tekabe, Y, Anthony, T, Li, Q, Schmidt, A M, Johnson, L, Groenman, M, Tarkia, M, Kakela, M, Halonen, P, Kiviniemi, T, Pietila, M, Yla-Herttuala, S, Roivainen, A, Nekolla, S, Swirzek, S, Higuchi, T, Reder, S, Schachoff, S, Bschorner, M, Laitinen, I, Robinson, S, Yousefi, B, Schwaiger, M, Kero, Tanja, Lindsjo, L, Antoni, Gunnar, Westermark, P, Carlson, K, Wikstrom, G, Sörensen, Jens, Lubberink, Mark, Rouzet, F, Cognet, T, Guedj, K, Morvan, M, El Shoukr, F, Louedec, L, Choqueux, C, Nicoletti, A, Le Guludec, D, Jimenez-Heffernan, A, Munoz-Beamud, F, Sanchez De Mora, E, Borrachero, C, Salgado, C, Ramos-Font, C, Lopez-Martin, J, Hidalgo, M L, Lopez-Aguilar, R, Soriano, E, Okizaki, A, Nakayama, M, Ishitoya, S, Sato, J, Takahashi, K, Burchert, I, Caobelli, F, Wollenweber, T, Nierada, M, Fulsche, J, Dieckmann, C, Bengel, F M, Shuaib, S, Mahlum, D, Port, S, Refoyo, E, Cuesta, E, Guzman, G, Lopez, T, Valbuena, S, Del Prado, S, Moreno, M, Harbinson, M, Donnelly, L, Einstein, A J, Johnson, L L, Deluca, A J, Kontak, A C, Groves, D W, Stant, J, Pozniakoff, T, Cheng, B, Rabbani, L E, Bokhari, S, Schuetze, C, Aguade-Bruix, S, Pizzi, M N, Romero-Farina, G, Terricabras, M, Villasboas, D, Castell-Conesa, J, Candell-Riera, J, Brunner, S, Gross, L, Todica, A, Lehner, S, Di Palo, A, Niccoli Asabella, A, Magarelli, C, Notaristefano, A, Ferrari, C, Rubini, G, Sellem, A, Melki, S, Elajmi, W, Hammami, H, Ziadi, M C, Montero, J, Ameriso, J L, Villavicencio, R L, Benito Gonzalez, T F, Mayorga Bajo, A, Gutierrez Caro, R, Rodriguez Santamarta, M, Alvarez Roy, L, Martinez Paz, E, Barinaga Martin, C, Martin Fernandez, J, Alonso Rodriguez, D, Iglesias Garriz, I, Rosillo, S, Taleb, S, Cherkaoui Salhi, G, Regbaoui, Y, Ait Idir, M, Guensi, A, Martin Lopez, C E, and Castano Ruiz, M
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- 2015
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6. Rapid Fire Abstract session: usefulness of CT and radionuclide imaging in different clinical scenarios378Improving the cost-effectiveness of chest pain investigations using single photon emission computed tomography379Is autonomic nervous dysfunction severity associated to less benefit from cardiac resynchronization therapy?380Validation of stress Thallium-201/Rest Technetium-99m sequential dual isotope high-speed myocardial perfusion imaging against fractional flow reserve for the detection of the extent of ischemia.381Nuclear imaging to predict adverse events in heart failure patients382Autonomic nervous system modulation in patients with heart failure and resynchronization after high intensity interval training383Long-term prediction of cardiac events using low-dose coronary ct angiography with prospective triggering384Left atrial appendage sizing for percutaneous occlusion with Amplatzer cardiac plug: a multimodality imaging approach385Evaluation of PAPVR using cardiac CT or MR imaging in patients with Turner syndrome.
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Lagan, J, primary, Rio, P, primary, Barone-Rochette, G, primary, Limeres Freire, J, primary, Abreu, A, primary, Clerc, O F, primary, Iriart, X, primary, Van Den Hoven, AT, primary, Meah, M, additional, Hasleton, J, additional, Mcshane, J, additional, Trent, R, additional, Abreu, A, additional, Santos, V, additional, Santa-Clara, H, additional, Oliveira, L, additional, Martins Oliveira, M, additional, Silva Cunha, P, additional, Moura Branco, L, additional, Mota Carmo, M, additional, Cruz Ferreira, R, additional, Zoreka, FZ, additional, Calizzano, A, additional, Vautrin, E, additional, Quesada, JL, additional, Broisat, A, additional, Riou, L, additional, Baguet, JP, additional, Fagret, D, additional, Ghezzi, C, additional, Rodriguez, J, additional, Oristrell, G, additional, Quiroga, X, additional, Pizzi, N, additional, Perez-Rodon, J, additional, Galve, E, additional, Aguade, S, additional, Santa Clara, H, additional, Oliveira, M, additional, Rio, P, additional, Cunha, P, additional, Portugal, G, additional, Ferreira, R, additional, Kaufmann, B P, additional, Possner, M, additional, Liga, R, additional, Vontobel, J, additional, Mikulicic, F, additional, Graeni, C, additional, Benz, D C, additional, Kaufmann, P A, additional, Buechel, R R, additional, Selmi, W, additional, Jalal, Z, additional, Thambo, JB, additional, Saru-Chelu, RG, additional, Duijnhouwer, AL, additional, Van Hagen, IM, additional, and Roos-Hesselink, JW, additional
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- 2015
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7. Young Investigator Award session – Clinical Science442Left bundle branch block and coronary artery disease in coronary ct angiography443Focal myocardial fibrosis and abnormal left ventricular strain in patients with sarcoidosis without clinical evidence of cardiac disease444Arhgap24, a first gene for fibro elastic deficiency mitral valve prolapse? A phenotypic study445Advantage of using ASE/EACVI criteria for detection of subclinical cardiotoxicity in breast cancer patients undergoing anthracycline and trastuzumab therapy
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Clerc, O F, primary, Lima Da Silva, G, primary, Jobbe Duval, A, primary, Santoro, C, primary, Possner, M, additional, Liga, R, additional, Fuchs, T A, additional, Dougoud, S, additional, Stehli, J, additional, Vontobel, J, additional, Mikulicic, F, additional, Kaufmann, P A, additional, Gaemperli, O, additional, Almeida, A M G, additional, David, C, additional, Francisco, AR, additional, Guimaraes, T, additional, Placido, R, additional, Menezes, M, additional, Pinto, FJ, additional, Rimbert, A, additional, Cueff, C, additional, Lecointe, S, additional, Hagege, AA, additional, Levine, R, additional, Merot, J, additional, Le Marec, H, additional, Schott, JJ, additional, Le Tourneau, T, additional, Lembo, M, additional, Esposito, R, additional, Cocozza, S, additional, Ilardi, F, additional, Arpino, G, additional, De Placido, S, additional, De Simone, G, additional, Trimarco, B, additional, and Galderisi, M, additional
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- 2015
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8. First experience with single-source, dual-energy CCTA for monochromatic stent imaging
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Stehli, J., primary, Fuchs, T. A., additional, Singer, A., additional, Bull, S., additional, Clerc, O. F., additional, Possner, M., additional, Gaemperli, O., additional, Buechel, R. R., additional, and Kaufmann, P. A., additional
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- 2014
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9. Coronary computed tomography angiography with model-based iterative reconstruction using a radiation exposure similar to chest X-ray examination
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Fuchs, T. A., primary, Stehli, J., additional, Bull, S., additional, Dougoud, S., additional, Clerc, O. F., additional, Herzog, B. A., additional, Buechel, R. R., additional, Gaemperli, O., additional, and Kaufmann, P. A., additional
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- 2014
- Full Text
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10. Consommation d'alcool, syndrome métabolique et diabète dans une population à consommation moyenne d'alcool élevée
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Clerc, O. F. and Clerc, O. F.
- Abstract
ButsDans la littérature actuelle, peu d'études existent sur la relation entre la consommation d'alcool et le syndrome métabolique. Les quelques données disponibles sont contradictoires et très limitées chez les buveurs à haut risque. Quant au diabète, une association est connue entre la consommation à bas risque d'alcool et une prévalence diminuée de la maladie. Là encore, les données sur la consommation à haut risque sont très limitées. Par conséquent, notre but était d'étudier la relation entre la consommation d'alcool, le syndrome métabolique et le diabète dans la cohorte lausannoise (CoLaus), où la consommation moyenne d'alcool est nettement plus élevée que dans la plupart des études disponibles, notamment celles des États-Unis.MéthodesNous avons analysé les données de 6172 hommes et femmes, âgés de 35 à 75 ans. La consommation d'alcool a été catégorisée en 0,1-6, 7-13, 14-20, 21-27, 28-34 et >35 boissons par semaine ou comme non-buveurs (0), buveurs à bas risque (1-13), à risque moyen à élevé (14-34) et à très haut risque (>35). Nous avons confirmé la consommation d'alcool par la y- glutamyl transferase et la transferrine déficiente en hydrates de carbone (CDT). Après l'analyse des caractéristiques des groupes de consommateurs, nous avons utilisé des régressions multivariées pour évaluer la relation entre la consommation d'alcool, la prévalence du syndrome métabolique et du diabète ainsi que la résistance à l'insuline, déterminée par le modèle d'homéostasie de la résistance à l'insuline (HOMA-IR). Dans le modèle d'ajustement, nous avons inclus l'âge, le genre, le status tabagique, l'activité physique et le niveau de formation. Nous avons aussi comparé la relation du type d'alcool (vin, bière et spiritueux) avec le syndrome métabolique, le diabète et le HOMA-IR en testant l'hypothèse d'égalité de leurs coefficients de régression, après ajustement.RésultatsParmi les participants, 73% buvaient de l'alcool, 16% étant buveurs à risque moyen à élevé et 2% à ris
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- 2011
11. Rapid Fire Abstract session: usefulness of CT and radionuclide imaging in different clinical scenarios
- Author
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Lagan, J, Meah, M, Hasleton, J, Mcshane, J, Trent, R, Rio, P, Abreu, A, Santos, V, Santa-Clara, H, Oliveira, L, Martins Oliveira, M, Silva Cunha, P, Moura Branco, L, Mota Carmo, M, Cruz Ferreira, R, Barone-Rochette, G, Zoreka, FZ, Calizzano, A, Vautrin, E, Quesada, JL, Broisat, A, Riou, L, Baguet, JP, Fagret, D, Ghezzi, C, Limeres Freire, J, Rodriguez, J, Oristrell, G, Quiroga, X, Pizzi, N, Perez-Rodon, J, Galve, E, Aguade, S, Abreu, A, Santa Clara, H, Santos, V, Oliveira, L, Oliveira, M, Rio, P, Cunha, P, Portugal, G, Ferreira, R, Mota Carmo, M, BETTER-HF, Clerc, O F, Kaufmann, B P, Possner, M, Liga, R, Vontobel, J, Mikulicic, F, Graeni, C, Benz, D C, Kaufmann, P A, Buechel, R R, Iriart, X, Selmi, W, Jalal, Z, Thambo, JB, Van Den Hoven, AT, Saru-Chelu, RG, Duijnhouwer, AL, Van Hagen, IM, and Roos-Hesselink, JW
- Abstract
Purpose: The National Institute for Health and Care Excellence (NICE) and the European Society of Cardiology (ESC) support the use of different cardiac imaging modalities in patients with suspected ischaemic heart disease (IHD). The cost of single photon emission computed tomography (SPECT) and invasive coronary angiography (ICA) in UK is estimated at £293 and £1052 respectively. Following positive SPECT, a large number of patients at our institution progressed to ICA which did not confirm significant coronary artery disease. As a result, a new SPECT scanner was acquired with ECG gating and in-built CT to correct for diaphragm / breast attenuation. Methods: We calculated cumulative cost of SPECT +/- ICA per patient before and after the scanner change. We screened patients with fixed / no defects on SPECT for acute coronary syndromes and cardiac related deaths in one year after the scan. Results: See Table 1. The new scanner detected significantly more fixed perfusion defects (p=0.0007, Fisher's exact test) and less reversible defects necessitating progression to ICA (p=0.001, Chi-square test). The cost of SPECT +/- ICA per patient was £713.8 in the old scanner group (£57,104 in total) and £468.3 in the new scanner group (£44,460 in total). Patients with normal SPECT or fixed defects did not have cardiac related deaths or acute coronary syndromes during following 12 months. Conclusions: The new scanner allowed for significant cost savings in our institution reducing the cost of SPECT +/- ICA from £713.8 to £468.3 per patient without compromising patients' safety. This is crucial in current climate of financial austerity. Our study was limited by the small number of patients and by the fact that many patients with reversible ischaemia were not referred for ICA due to different reasons: minor symptoms / ischaemia on SPECT (n=15), patients not attending follow up (n=3), non cardiac death (n=1), other imaging modalities chosen (n=2).
Old Scanner New Scanner Number of SPECT 80 96 Reversible defect on SPECT 42 (52.5%) 27 (28.1%) Fixed defect on SPECT 3 (3.75%) 20 (20.8%) Number of ICA 32 (40%) 16 (16.7%) Cost of SPECT +/- ICA per patient £713.8 £468.3 SPECT/ICA results - Published
- 2015
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12. Young Investigator Award session - Clinical Science
- Author
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Clerc, O F, Possner, M, Liga, R, Fuchs, T A, Dougoud, S, Stehli, J, Vontobel, J, Mikulicic, F, Kaufmann, P A, Gaemperli, O, Lima Da Silva, G, Almeida, A M G, David, C, Francisco, AR, Guimaraes, T, Placido, R, Menezes, M, Pinto, FJ, Jobbe Duval, A, Rimbert, A, Cueff, C, Lecointe, S, Hagege, AA, Levine, R, Merot, J, Le Marec, H, Schott, JJ, Le Tourneau, T, Santoro, C, Lembo, M, Esposito, R, Cocozza, S, Ilardi, F, Arpino, G, De Placido, S, De Simone, G, Trimarco, B, and Galderisi, M
- Abstract
Purpose: Left bundle branch block (LBBB) is considered an unfavourable prognostic marker in heart disease. Testing for coronary artery disease (CAD) is often prompted by incidental LBBB finding, but published studies disagree about an association between LBBB and CAD. Thus, we assessed the association of LBBB with CAD in patients undergoing coronary CT angiography (CCTA). Methods: We enrolled 818 patients (106 LBBB patients and 712 controls) without known CAD, cardiomyopathy, valvular or congenital heart disease who underwent CCTA. Image quality was assessed on a 4-point scale for each coronary segment. After exclusion of non-diagnostic studies, comparison of CAD prevalence (≥50% coronary stenosis) was performed using triple case-matching for pre-test probability (based on age, gender and typicality of symptoms) in 101 LBBB patients and 303 matched controls. Results: Mean age was 57.2 ± 11.1 years. CAD prevalence did not differ between LBBB patients and matched controls: 15% vs. 16% (p=0.88). Similarly, no significant differences were found in cardiovascular risk factors (CVRF), stenosis severity, CAD extent, non-obstructive disease and vessel-based analysis. In multivariate analysis, age, gender, typical angina and CVRF, but not LBBB (p=0.94), emerged as significant and independent predictors of obstructive CAD. Image quality was very high in LBBB and controls (3.8 versus 3.9). LBBB did not affect image quality in multivariate analysis including technical factors (p=0.70). Conclusion: CAD prevalence is similar in LBBB patients at low-to-moderate pre-test probability compared to controls matched for age, gender, symptom typicality and CVRF. LBBB does not affect image quality in CCTA, which is therefore a useful imaging modality in LBBB patients.
Prevalence of CAD by severity - Published
- 2015
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