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44 results on '"Clemow, David B"'

1. Two-Year Efficacy and Safety of Mirikizumab Following 104 Weeks of Continuous Treatment for Ulcerative Colitis: Results From the LUCENT-3 Open-Label Extension Study.

Author

Sands, Bruce E, D'Haens, Geert, Clemow, David B, Irving, Peter M, Johns, Jordan T, Gibble, Theresa Hunter, Abreu, Maria T, Lee, Scott, Hisamatsu, Tadakazu, Kobayashi, Taku, Dubinsky, Marla C, Vermeire, Severine, Siegel, Corey A, Peyrin-Biroulet, Laurent, Moses, Richard E, Milata, Joe, Arora, Vipin, Panaccione, Remo, and Dignass, Axel

Published
2024
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2. Misuse of Methylphenidate

Author

Clemow, David B., Geyer, Mark A., Series editor, Ellenbroek, Bart A., Series editor, Marsden, Charles A., Series editor, Barnes, Thomas R.E., Series editor, L. Andersen, Susan, Series editor, Nielsen, Suzanne, editor, Bruno, Raimondo, editor, and Schenk, Susan, editor

Published
2017
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3. S848 Two-Year Efficacy and Safety of Mirikizumab Following 104 Weeks of Continuous Treatment: Interim Results From the LUCENT-3 Open-Label Extension Study

Author

Sands, Bruce E., primary, D'Haens, Geert, additional, Clemow, David B., additional, Irving, Peter M., additional, Johns, Jordan, additional, Gibble, Theresa Hunter, additional, Abreu, Maria T., additional, Lee, Scott, additional, Hisamatsu, Tadakazu, additional, Kobayashi, Taku, additional, Dubinsky, Marla C., additional, Vermeire, Séverine, additional, Siegel, Corey A., additional, Peyrin-Biroulet, Laurent, additional, Moses, Richard E., additional, Milata, Joe, additional, Arora, Vipin, additional, Panaccione, Remo, additional, and Dignass, Axel, additional

Published
2023
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5. Medical Writing Competency Model — Section 1: Functions, Tasks, and Activities

Author

Clemow, David B., Wagner, Bertil, Marshallsay, Christopher, Benau, Dan, L’Heureux, Darryl, Brown, David H., Dasgupta, Devjani Ghosh, Girten, Eileen, Hubbard, Frank, Gawrylewski, Helle-Mai, Ebina, Hiroko, Stoltenborg, Janet, York, J. P., Green, Kim, Wood, Linda Fossati, Toth, Lisa, Mihm, Michael, Katz, Nancy R., Vasconcelos, Nina-Maria, Sakiyama, Norihisa, Whitsell, Robin, Gopalakrishnan, Shobha, Bairnsfather, Susan, Wanderer, Tatyana, Schindler, Thomas M., Mikyas, Yeshi, and Aoyama, Yumiko

Published
2018
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6. Medical Writing Competency Model — Section 2: Knowledge, Skills, Abilities, and Behaviors

Author

Clemow, David B., Wagner, Bertil, Marshallsay, Christopher, Benau, Dan, L’Heureux, Darryl, Brown, David H., Dasgupta, Devjani Ghosh, Girten, Eileen, Hubbard, Frank, Gawrylewski, Helle-Mai, Ebina, Hiroko, Stoltenborg, Janet, York, J. P., Green, Kim, Wood, Linda Fossati, Toth, Lisa, Mihm, Michael, Katz, Nancy R., Vasconcelos, Nina-Maria, Sakiyama, Norihisa, Whitsell, Robin, Gopalakrishnan, Shobha, Bairnsfather, Susan, Wanderer, Tatyana, Schindler, Thomas M., Mikyas, Yeshi, and Aoyama, Yumiko

Published
2018
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21. Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding

Author

Clemow, David B., Steers, William D., McCarty, Richard, and Tuttle, Jeremy B.

Subjects
Nerve growth factor -- Physiological aspects, Hypertension -- Physiological aspects, Urination -- Physiological aspects, Rats -- Physiological aspects, Biological sciences
Abstract

The factors influencing the high levels of nerve growth factor (NGF) seen in spontaneously hypertensive rats (SHRs) were investigated and the role of elevated NGF in hyperactive voiding was examined. Findings indicate that the high tissue NGF presence in SHRs was a result of the high basal NGF secretion of the vascular and bladder smooth muscle cells in SHR. Moreover, a defect in the regulation of NGF production in SHR smooth muscle cells result in the suppression of the inhibitory signaling pathways and the hyperresponsiveness of excitatory signaling mechanisms of NGF production.

Published
1998

22. Expanding Horizons as a Medical Writer.

Author

Clemow, David B.

Subjects
*AWARDS, *COMMUNICATION, *CONFERENCES & conventions, *INFORMATION display systems, *MEDICAL technology, *MEDICAL writing, *VOCATIONAL guidance, *CERTIFICATION, *JOB performance
Published
2020

26. Atomoxetine monotherapy compared with combination therapy for the treatment of ADHD: a retrospective chart review study

Author

Clemow, David B., primary, Mason, Oren W., additional, Sarkis, Elias H., additional, Ruff, Dustin D., additional, Berman, Brad D., additional, Donnelly, Craig L., additional, Robb, Adelaide S., additional, Holland, Donna S., additional, Schuh, Kory J., additional, Barnes, Janet M., additional, and Araujo, Andre B., additional

Published
2015
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29. A review of the efficacy of atomoxetine in the treatment of attention-deficit hyperactivity disorder in children and adult patients with common comorbidities.

Author

Clemow, David B., Bushe, Chris, Mancini, Michele, Ossipov, Michael H., and Upadhyaya, Himanshu

Subjects
*ATTENTION-deficit hyperactivity disorder, *ATTENTION-deficit disorder in adults, *ATOMOXETINE, *COMORBIDITY, *PATIENTS, *THERAPEUTICS
Abstract

Attention-deficit hyperactivity disorder (ADHD) is a common neuropsychiatric disorder that is often diagnosed during childhood, but has also increasingly been recognized to occur in adults. Importantly, up to 52% of children (including adolescents) and 87% of adults with ADHD also have a comorbid psychiatric disorder. The presence of a comorbid disorder has the potential to impact diagnosis and could affect treatment outcomes. Atomoxetine is a nonstimulant treatment for ADHD. Despite numerous published studies regarding efficacy of atomoxetine in the treatment of ADHD in patients with comorbid disorders, there is limited information about the impact of individual common comorbid disorders on the efficacy of atomoxetine for ADHD, especially with regard to adults. Moreover, a cumulative review and assessment of these studies has not been conducted. For this reason, we performed a literature review to find, identify, and cumulatively review clinical studies that examined the efficacy of atomoxetine in the treatment of patients with ADHD and comorbid psychiatric disorders. We found a total of 50 clinical studies (37 in children; 13 in adults) that examined the efficacy of atomoxetine in patients with ADHD and a comorbid disorder. The comorbidities that were studied in children or in adults included anxiety, depression, and substance use disorder. Overall, the presence of comorbidity did not adversely impact the efficacy of atomoxetine in treatment of ADHD symptoms in both patient populations. In the studies identified and assessed in this review, atomoxetine did not appear to exacerbate any of the comorbid conditions and could, therefore, be an important therapy choice for the treatment of ADHD in the presence of comorbid disorders. [ABSTRACT FROM AUTHOR]

Published
2017
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42. PHARMACEUTICAL MEDICAL WRITING COMPETENCY MODEL: PRACTICAL APPLICATIONS.

Author

Clemow, David B.

Subjects
*AUTHORSHIP, *CLINICAL competence, *EMPLOYEE selection, *EMPLOYEE recruitment, *PERSONNEL management, *PUBLISHING, *EMPLOYEE retention, *ORGANIZATIONAL structure, *NATIONAL competency-based educational tests
Abstract

This article describes the practical applications of a medical writing competency model developed by a medical writing task force associated with the Drug Information Association. The model describes work functions, activities, knowledge, skills, and behaviors deemed necessary to perform successfully as a medical writer in the pharmaceutical industry. The focus of this article is on how the model can be a professional tool to help medical writers and medical writing organizations with organizational structure development; recruiting and hiring; onboarding, training, and development; setting expectations and aligning to assignments; performance evaluation and staff retention; and defining the profession. [ABSTRACT FROM AUTHOR]

Published
2011

44. PHYSIOLOGICAL SOCIETY SYMPOSIUM: THE PHYSIOLOGY AND PATHOPHYSIOLOGY OF THE LOWER URINARY TRACT: THE SPONTANEOUSLY HYPERTENSIVE RAT: INSIGHT INTO THE PATHOGENESIS OF IRRITATIVE SYMPTOMS IN BENIGN PROSTATIC HYPERPLASIA AND YOUNG ANXIOUS MALES

Author

STEERS, WILLIAM D., CLEMOW, DAVID B., PERSSON, KATARINA, SHERER, TODD B., ANDERSSON, KARL‐ERIK, and TUTTLE, JEREMY B.

Abstract

Recent epidemiological studies have shown that hypertensive men are more likely to undergo surgical intervention for irritative voiding symptoms from BPH than age‐matched controls. Indeed, noradrenergic nerves which regulate vascular tone also participate in the functional component of bladder outlet obstruction due to BPH. Newer, less invasive therapies for BPH such as thermal therapy can relieve symptoms yet do not eliminate obstruction based on urodynamic studies. Coincidentally, drugs such as α‐adrenoceptor antagonists, which have been thought to relieve obstruction due to a peripheral effect, can be given intrathecally in animals to relieve urinary frequency due to obstruction. Taken together these observations implicate both peripheral and central sympathetic pathways in the motor control of the urinary bladder especially with disease states.

Published
1999
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