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20 results on '"Clemm, Hege H."'

6. Left Vocal Cord Paralysis, Lung Function and Exercise Capacity in Young Adults Born Extremely Preterm With a History of Neonatal Patent Ductus Arteriosus Surgery—A National Cohort Study

Author

Engan, Mette, primary, Engeset, Merete S., additional, Sandvik, Lorentz, additional, Gamlemshaug, Ole C. O., additional, Engesæter, Ingvild Ø., additional, Øymar, Knut, additional, Vollsæter, Maria, additional, Røksund, Ola D., additional, Hufthammer, Karl Ove, additional, Halvorsen, Thomas, additional, and Clemm, Hege H., additional

Published
2022
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14. Severe Exercise-Induced Laryngeal Obstruction Treated With Supraglottoplasty

Author

Sandnes, Astrid, primary, Hilland, Magnus, additional, Vollsæter, Maria, additional, Andersen, Tiina, additional, Engesæter, Ingvild Øvstebø, additional, Sandvik, Lorentz, additional, Heimdal, John-Helge, additional, Halvorsen, Thomas, additional, Eide, Geir Egil, additional, Røksund, Ola Drange, additional, and Clemm, Hege H., additional

Published
2019
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20. Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended.

Author

Muralitharan P, Carlsen P, Hilland M, Delestre-Levai I, Vollsæter M, Hufthammer KO, Engan M, Røksund OD, Halvorsen T, and Clemm HH

Abstract

Introduction: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young adults. Current management generally consists of breathing advice, speech therapy, inspiratory muscle training or supraglottoplasty in highly motivated subjects with supraglottic collapse. Inhaled ipratropium bromide (IB) is a muscarinic receptor antagonist used to treat asthma that is suggested in a few reports to improve EILO symptoms. The aim of the present study was to investigate effects of inhaled IB in EILO diagnosed by continuous laryngoscopy exercise (CLE) test and classified by CLE scores., Methods: A randomised crossover trial was conducted at Haukeland University Hospital, Bergen, Norway, enrolling participants diagnosed with EILO defined by characteristic symptoms and CLE score ≥3 (range 0-12). Two consecutive CLE tests were performed within 2 weeks, one test with and one test without prior administration of inhaled IB in a randomised order. Main outcomes were the CLE score, dyspnoea measured using a modified BORG scale (range 0-10) and cardiopulmonary exercise data provided by the CLE test., Results: 20 participants (14 females) aged 12-25 years participated, and all ran to exhaustion on both tests. Mean CLE score, BORG score and peak oxygen consumption were similar in tests performed with and without IB; mean differences (95% confidence interval) were 0.08 (-0.28-0.43), 0.35 (-0.29-0.99) and -0.4 (-1.9-1.1) mL·kg -1 ·min -1 , respectively., Conclusion: Inhaled IB did not improve CLE score, dyspnoea or exercise capacity in subjects with EILO. The study does not support the use of inhaled IB to treat EILO., Competing Interests: Conflict of interest: The authors have no conflicts of interest to disclose., (Copyright ©The authors 2023.)

Published
2023
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