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17 results on '"Clemens, C. H M"'

1. Smoking is Associated with Higher Disease-related Costs and Lower Health-related Quality of Life in Inflammatory Bowel Disease

Author

Severs, M., Mangen, M-J. J., van der Valk, M. E., Fidder, H. H., Dijkstra, G., van der Have, M., van Bodegraven, A. A., de Jong, D. J., van der Woude, C. J., Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J. M., van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Vermeijden, J. R., van der Meulen- de Jong, A. E., Pierik, M., Siersema, P. D., and Oldenburg, B.

Published
2017
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2. Smoking is Associated With Extra-intestinal Manifestations in Inflammatory Bowel Disease

Author

Severs, M., van Erp, S. J. H., van der Valk, M. E., Mangen, M. J. J., Fidder, H. H., van der Have, M., van Bodegraven, A. A., de Jong, D. J., van der Woude, C. J., Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J. M., van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerk, C., Vermeijden, J. R., Pierik, M. J., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., Dijkstra, G., and Oldenburg, B.

Published
2016
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7. Smoking is Associated with Higher Disease-related Costs and Lower Health-related Quality of Life in Inflammatory Bowel Disease

Author

UMC Utrecht, Unit Opleiding Aios, Cancer, HEE, MS MDL 1, Infection & Immunity, Severs, M., Mangen, M. J.J., van der Valk, M. E., Fidder, H. H., Dijkstra, G., van der Have, M., Van Bodegraven, Ad A., de Jong, J., van der Woude, C Janneke, Romberg-Camps, Mariëlle J L, Clemens, C. H. M., Jansen, J. M., van de Meeberg, Paul C, Mahmmod, N., Ponsioen, Cyriel Y, Vermeijden, Jacob R., Van der Meulen-de Jong, Andrea E, Pierik, M., Siersema, P. D., Oldenburg, B., COIN study group and the Dutch Initiative on Crohn and Colitis, UMC Utrecht, Unit Opleiding Aios, Cancer, HEE, MS MDL 1, Infection & Immunity, Severs, M., Mangen, M. J.J., van der Valk, M. E., Fidder, H. H., Dijkstra, G., van der Have, M., Van Bodegraven, Ad A., de Jong, J., van der Woude, C Janneke, Romberg-Camps, Mariëlle J L, Clemens, C. H. M., Jansen, J. M., van de Meeberg, Paul C, Mahmmod, N., Ponsioen, Cyriel Y, Vermeijden, Jacob R., Van der Meulen-de Jong, Andrea E, Pierik, M., Siersema, P. D., Oldenburg, B., and COIN study group and the Dutch Initiative on Crohn and Colitis

Published
2017

8. Smoking is associated with extra-intestinal manifestations in inflammatory bowel disease

Author

MS MDL 1, Cancer, HTA Onderzoek Team 1, JC onderzoeksprogramma Infectieziekten, Circulatory Health, JC onderzoeksprogramma Methodologie, Infection & Immunity, Unit Opleiding Aios, Severs, M., van Erp, S. J H, van der Valk, M. E., Mangen, M. J J, Fidder, H. H., van der Have, M., van Bodegraven, A. A., de Jong, D. J., van der Woude, C. J., Romberg-Camps, M. J L, Clemens, C. H M, Jansen, J. M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerkm, C., Vermeijden, J. R., Pierik, M. J., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., Dijkstra, G., Oldenburg, Bas, MS MDL 1, Cancer, HTA Onderzoek Team 1, JC onderzoeksprogramma Infectieziekten, Circulatory Health, JC onderzoeksprogramma Methodologie, Infection & Immunity, Unit Opleiding Aios, Severs, M., van Erp, S. J H, van der Valk, M. E., Mangen, M. J J, Fidder, H. H., van der Have, M., van Bodegraven, A. A., de Jong, D. J., van der Woude, C. J., Romberg-Camps, M. J L, Clemens, C. H M, Jansen, J. M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerkm, C., Vermeijden, J. R., Pierik, M. J., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., Dijkstra, G., and Oldenburg, Bas

Published
2016

9. Smoking is associated with extra-intestinal manifestations in inflammatory bowel disease

Author

Severs, M., van Erp, S., Dijkstra, G., van der Valk, M. E., Mangen, M. -J., van der Have, M., van Bodegraven, A. A., Fidder, H. H., de Jong, D. J., Pierik, M., van der Woude, J, Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerk, C. J., Vermeijden, J. R., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., Oldenburg, B., Severs, M., van Erp, S., Dijkstra, G., van der Valk, M. E., Mangen, M. -J., van der Have, M., van Bodegraven, A. A., Fidder, H. H., de Jong, D. J., Pierik, M., van der Woude, J, Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerk, C. J., Vermeijden, J. R., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., and Oldenburg, B.

Published
2015

10. Comparison of costs and quality of life in ulcerative colitis patients with an ileal pouch-anal anastomosis, ileostomy and anti-TNFα therapy

Author

van der Valk, M.E., Mangen, MJJ, Severs, M, van der Have, M, Dijkstra, G., van Bodegraven, A.A., Fidder, HH, de Jong, D.J., Pierik, M., van der Woude, C.J., Romberg-Camps, M.J., Clemens, C. H. M., Jansen, J.M., van de Meeberg, P.C., Mahmmod, N., van der Meulen-de Jong, A.E., Ponsioen, C.Y., Bolwerk, C.J.M., Vermeijden, J.R., Siersema, PD, Leenders, Max, Oldenburg, B, van der Valk, M.E., Mangen, MJJ, Severs, M, van der Have, M, Dijkstra, G., van Bodegraven, A.A., Fidder, HH, de Jong, D.J., Pierik, M., van der Woude, C.J., Romberg-Camps, M.J., Clemens, C. H. M., Jansen, J.M., van de Meeberg, P.C., Mahmmod, N., van der Meulen-de Jong, A.E., Ponsioen, C.Y., Bolwerk, C.J.M., Vermeijden, J.R., Siersema, PD, Leenders, Max, and Oldenburg, B

Published
2015

11. Smoking is associated with extra-intestinal manifestations in inflammatory bowel disease

Author

MS MDL 1, Cancer, HTA Onderzoek Team 1, JC onderzoeksprogramma Infectious Diseases, JC onderzoeksprogramma Methodology, Unit Opleiding Aios, Infection & Immunity, Severs, M., van Erp, S., Dijkstra, G., van der Valk, M. E., Mangen, M. -J., van der Have, M., van Bodegraven, A. A., Fidder, H. H., de Jong, D. J., Pierik, M., van der Woude, J, Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerk, C. J., Vermeijden, J. R., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., Oldenburg, B., MS MDL 1, Cancer, HTA Onderzoek Team 1, JC onderzoeksprogramma Infectious Diseases, JC onderzoeksprogramma Methodology, Unit Opleiding Aios, Infection & Immunity, Severs, M., van Erp, S., Dijkstra, G., van der Valk, M. E., Mangen, M. -J., van der Have, M., van Bodegraven, A. A., Fidder, H. H., de Jong, D. J., Pierik, M., van der Woude, J, Romberg-Camps, M. J. L., Clemens, C. H. M., Jansen, J M, van de Meeberg, P. C., Mahmmod, N., Ponsioen, C. Y., Bolwerk, C. J., Vermeijden, J. R., Siersema, P. D., Leenders, M., van der Meulen-de Jong, A. E., and Oldenburg, B.

Published
2015

12. Smoking is Associated With Extra-intestinal Manifestations in Inflammatory Bowel Disease

Author

Severs, M., primary, van Erp, S. J. H., additional, van der Valk, M. E., additional, Mangen, M. J. J., additional, Fidder, H. H., additional, van der Have, M., additional, van Bodegraven, A. A., additional, de Jong, D. J., additional, van der Woude, C. J., additional, Romberg-Camps, M. J. L., additional, Clemens, C. H. M., additional, Jansen, J. M., additional, van de Meeberg, P. C., additional, Mahmmod, N., additional, Ponsioen, C. Y., additional, Bolwerk, C., additional, Vermeijden, J. R., additional, Pierik, M. J., additional, Siersema, P. D., additional, Leenders, M., additional, van der Meulen-de Jong, A. E., additional, Dijkstra, G., additional, and Oldenburg, B., additional

Published
2015
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14. Abnormalities of left colonic motility in ambulant nonconstipated patients with irritable bowel syndrome

Author

Clemens, C. H. M., Samsom, M., van Berge Henegouwen, G. P., Smout, A. J. P. M., and Other departments

Abstract

Our objective was to evaluate left colonic motility patterns recorded under physiological conditions during 24 hr in fully ambulant nonconstipated IBS patients compared to healthy controls. A 42-hr manometry of the left colon was performed in 11 nonconstipated IBS patients and 10 age- and sex-matched healthy volunteers. On day 1, a 6-channel, 10-cm interval, solid-state catheter was positioned. Frequency, amplitude, and motility index (MI) of segmenting pressure waves in the descending and sigmoid colon were calculated during the 24-hr study period on day 2. High-amplitude propagated contractions (HAPCs) were identified visually and their characteristics were calculated. In IBS patients a higher frequency of segmenting pressure waves was observed in the sigmoid colon compared to the descending colon (P = 0.006). In contrast, no regional differences were observed in controls. Awakening (P = 0.048) as well as having a meal (P = 0.024) was associated with a smaller increase of contraction frequency in the descending colon of IBS patients compared to controls. HAPCs occurred more frequently in IBS patients than in controls (P = 0.035). HAPCs in IBS patients reached a more distal colonic level and occurred more frequently in clusters. Defecation in IBS patients, but not in controls was always preceded by a cluster of HAPCs. In conclusion, left colonic segmenting pressure waves and HAPC characteristics are altered in nonconstipated IBS patients

Published
2003

16. Association between pain episodes and high amplitude propagated pressure waves in patients with irritable bowel syndrome.

Author

Clemens CH, Samsom M, Roelofs JM, van Berge Henegouwen GP, and Smout AJ

Subjects
Adult, Colon physiology, Colonic Diseases, Functional complications, Female, Humans, Male, Manometry, Monitoring, Ambulatory, Pain complications, Colon physiopathology, Colonic Diseases, Functional physiopathology, Gastrointestinal Motility physiology, Pain physiopathology
Abstract

Objectives: In the pathogenesis of irritable bowel syndrome (IBS), both increased visceral sensitivity and altered colonic motility seem to play a role. The aim of this study was to quantify the temporal relationship between pain episodes and the occurrence of high amplitude propagated pressure waves (HAPPWs)., Methods: A total of 11 IBS patients with the nonconstipation predominant pattern of IBS and 10 sex- and age-matched healthy volunteers were studied. On day 1, a solid state manometric catheter was positioned in the left colon and connected to a data logger. The subjects then went home. Thereafter they pressed a button on the data logger at the beginning and end of each pain episode. The 24-h manometric signal recorded on day 2 was divided into consecutive 5-min periods. These periods were evaluated for the occurrence of pain and HAPPWs. Fisher's exact test was applied to calculate the probability that HAPPWs and pain episodes were unrelated. The symptom association probability (SAP) was calculated as (1.0 - P) x 100%. A SAP of >95% was considered to indicate that the observed association did not occur by chance., Results: In four of seven patients with pain on day 2, the SAP was >95%. HAPPWs that were related to pain originated at a more proximal level (p = 0.026) and occurred earlier (p = 0.007) than HAPPWs that were not related to pain. The duration of a pain period was correlated with the number of pain-related HAPPWs in that period (r = 0.906, p = 0.013). Two of the 10 healthy subjects experienced pain, and these pain episodes were not associated with HAPPWs., Conclusions: Using objective analysis techniques, an association between pain episodes and HAPPWs was found in nonconstipated IBS patients with pain. HAPPWs that are associated with pain are only slightly different from HAPPWs not associated with pain.

Published
2003
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17. Abnormalities of left colonic motility in ambulant nonconstipated patients with irritable bowel syndrome.

Author

Clemens CH, Samsom M, Van Berge Henegouwen GP, and Smout AJ

Subjects
Adult, Case-Control Studies, Circadian Rhythm, Constipation, Defecation physiology, Female, Humans, Incidence, Male, Manometry, Colon physiopathology, Colonic Diseases, Functional physiopathology, Gastrointestinal Motility physiology
Abstract

Our objective was to evaluate left colonic motility patterns recorded under physiological conditions during 24 hr in fully ambulant nonconstipated IBS patients compared to healthy controls. A 42-hr manometry of the left colon was performed in 11 nonconstipated IBS patients and 10 age- and sex-matched healthy volunteers. On day 1, a 6-channel, 10-cm interval, solid-state catheter was positioned. Frequency, amplitude, and motility index (MI) of segmenting pressure waves in the descending and sigmoid colon were calculated during the 24-hr study period on day 2. High-amplitude propagated contractions (HAPCs) were identified visually and their characteristics were calculated. In IBS patients a higher frequency of segmenting pressure waves was observed in the sigmoid colon compared to the descending colon (P = 0.006). In contrast, no regional differences were observed in controls. Awakening (P = 0.048) as well as having a meal (P = 0.024) was associated with a smaller increase of contraction frequency in the descending colon of IBS patients compared to controls. HAPCs occurred more frequently in IBS patients than in controls (P = 0.035). HAPCs in IBS patients reached a more distal colonic level and occurred more frequently in clusters. Defecation in IBS patients, but not in controls was always preceded by a cluster of HAPCs. In conclusion, left colonic segmenting pressure waves and HAPC characteristics are altered in nonconstipated IBS patients.

Published
2003
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