64 results on '"Cleary SD"'
Search Results
2. PHS47 - A Cross Sectional Study of the Factors that Affect Therapy Adherence in Children with Attention Deficit Disorder/ Attention Deficit/Hyperactivity Disorder
- Author
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Saeed, NS, Cleary, SD, and Maneno, M
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- 2018
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3. The validity of self-reports of smoking: analyses by race/ethnicity in a school sample of urban adolescents.
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Wills TA and Cleary SD
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OBJECTIVES: This research compared the validity of self-reports of cigarette smoking for African-American, Hispanic, and White respondents. Previous research has raised a question about the validity of self-report for African Americans. METHODS: A self-report of cigarette smoking was obtained together with a measure of carbon monoxide from expired air. Convergence between self-reported smoking and the biochemical measure was analyzed separately for three ethnic groups at 7th grade, 8th grade, 9th grade, and 10th grade. RESULTS: Analyses indicated that the validity of self-reports of smoking was generally comparable across ethnic groups. Sensitivity and specificity were comparable with data reported in recent meta-analyses. Though sensitivity was slightly lower for minority adolescents than for White adolescents, prevalence rates corrected for group differences in sensitivity showed significantly lower smoking rates for African-American and Hispanic adolescents than for White adolescents. CONCLUSIONS: The lower smoking rates reported for African-American adolescents are real and are not substantially a consequence of reporting artifacts. [ABSTRACT FROM AUTHOR]
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- 1997
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4. Cognitive and academic functioning of homeless children compared with housed children.
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Rubin DH, Erickson CJ, San Agustin M, Cleary SD, Allen JK, and Cohen P
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- 1996
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5. Adolescent victimization and associated suicidal and violent behaviors.
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Cleary SD
- Abstract
This study examined the relationship between victimization and both suicidal and violent behaviors among 1,569 public high school students in New York State (excluding New York City). They had participated in the 1997 Youth Risk Behavior Survey and, based on their responses, were divided into four groups: no suicidal or violent behavior, suicidal behavior only, violent behavior only, and both suicidal and violent behaviors. Males reported significantly more victimization, less suicidal behavior, and more violent behavior compared with females. Logistic regression analyses indicated that all categories of suicidal/violent behaviors were more frequent among those who had been victimized compared with the nonvictimized, for both males and females. In addition, victimized males were over two times more likely than victimized females to report violent behavior only. Gender differences were not significant for victimized students in two groups, suicidal behavior only and both suicidal and violent behaviors, although the results were in the hypothesized direction for suicidal behavior (e.g., females were more prone to suicidal behavior only). It was concluded that identifying and treating the victims of violence should be an integral component of suicide prevention programs and interventions aimed at reducing interpersonal violence in schools. [ABSTRACT FROM AUTHOR]
- Published
- 2000
6. Attitudes of Forensic Fellowship Psychiatry Directors towards an Applicant Match.
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Gupta DR, Candilis PJ, Choi O, Abi Zeid Daou M, Kapoor R, Cleary SD, Binder R, and Ash P
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- Humans, United States, Surveys and Questionnaires, Personnel Selection, Attitude of Health Personnel, Female, Physician Executives, Male, Adult, Fellowships and Scholarships, Forensic Psychiatry education
- Abstract
Forensic psychiatry fellowship programs recruit applicants through a nonstandardized process that differs by program. Although there are deadlines, informal guidance, and more recent communication guidelines, perceived differences in recruitment practices persist between geographic regions, small and large programs, and newer and more well-established programs. In the wake of a survey of fellowship applicants that found mixed opinions surrounding the application process, U.S. forensic fellowship directors undertook a mixed method quantitative-qualitative survey of their colleagues to assess interest in a match as a potential improvement and factors influencing that interest (e.g., program size, age, and unfilled positions). With responses from all 46 active U.S. programs, results indicated broad support for principles of fairness, transparency, and minimizing pressure on applicants, with an almost perfectly divided interest in a match. Respondents supported the use of a centralized database to standardize the application process and favored certain exceptions for internal applicants. Hypotheses about the reasons underlying program directors' attitudes toward a match did not yield significant results, with only the size of a program approaching significance. This novel comprehensive survey of forensic fellowship directors offers a model for assessing and monitoring the evolution of application processes for medical subspecialties interested in expanding and improving their recruitment., (© 2024 American Academy of Psychiatry and the Law.)
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- 2024
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7. Value-driven attitude surveys: Lessons from the refugee crisis in Greece.
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Qadir S, Feruni J, Mastora A, Karampoutakis G, Tveit M, Nikopoulos S, Anitsi E, Cleary SD, Dyer AR, and Candilis PJ
- Abstract
Community reaction to refugees and asylum-seekers is often gauged by attitude surveys that are not designed to overcome built-in bias. Questionnaires that do not account for context and background consequently yield results that misrepresent community attitudes and offer predictably negative responses to immigrant groups. Such surveys can alter public perception, fuel anti-refugee sentiment, and affect policy simply because of how they are constructed. This model survey among humanitarian aid-workers from nine Greek non-governmental organizations uses specific techniques designed to overcome these challenges by applying sample familiarity, non-inflammatory hypothesis-testing, educational question stems, intentional ordering of questions, and direct questioning rather than surrogate measures like statistical approximation. Respondents working in the refugee crisis in Greece demonstrate how empathy, education, and exposure to refugees serve to overcome the harmful stereotypes of outsiders as contributors to crime, terror, and social burden., Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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8. Pathway to terrorist behaviors: The role of childhood experiences, personality traits, and ideological motivations in a sample of Iraqi prisoners.
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Cleary SD, Candilis PJ, Dhumad S, Dyer AR, and Khalifa N
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- Male, Adult, Humans, Iraq, Motivation, Cross-Sectional Studies, Antisocial Personality Disorder, Terrorism, Prisoners, Spiperone analogs & derivatives
- Abstract
Radicalization to terrorism is a multifaceted process with no single theory or approach to explain it. Although research has focused on understanding the process, there is still a dearth of studies that examine an empirically driven pathway to terrorism behavior. This study examines a cross-sectional sample of incarcerated men convicted of terrorism in Iraq (N = 160). A questionnaire-guided interview included adverse childhood experiences (ACEs), conduct disorder (CD), antisocial personality disorder (ASPD), religious and political ideology, views about causes of terrorism, and the severity of terrorist acts. Path analysis was employed to examine the relationships between these factors and to identify the model with the best fit. After adjusting for age, employment, and location, results indicated that ACEs positively impacted CD, ASPD, religious guidance, and terrorism attitudes. ASPD positively affected political commitment and terrorism attitudes, but inversely affected current religious commitment. Political commitment inversely influenced terrorism attitudes. Religious commitment positively influenced the prioritization of religion in life, which subsequently impacted terrorism attitudes and behavior severity. Additionally, attitudes toward terrorism directly affected the severity of terrorism behavior. All paths in the final model were statistically significant at p < 0.05. Although these findings may be limited in generalizability due to the unique sample, results support the complex and interdependent nature of childhood and adult experiences on the development of both terrorism attitudes and the severity of terrorism behavior., (© 2023 American Academy of Forensic Sciences.)
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- 2024
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9. Assessing Racial Effects on Adjudicative Competence.
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Hobart KS, Krishnan S, Cleary SD, and Candilis PJ
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- Humans, Mental Competency psychology, Retrospective Studies, Psychological Tests, Forensic Psychiatry methods, Mental Disorders psychology
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As racial influences on forensic outcomes are identified in every aspect of practice, scholars are exploring methods to disentangle race from its historical, economic, and attitudinal antecedents. Because jurisdictions vary in these influences, definitions and data may differ among them, creating inconsistencies in analysis and policy. This retrospective database review compared differences in racial outcomes among 200 pretrial defendants, 160 Black and 40 White, exploring a wide range of socioeconomic, clinical, and forensic influences before, during, and after hospitalization. Because of the tight relationship of socioeconomic factors and race, investigators hypothesized that it would be difficult to distinguish racial influences alone. Using a confirmatory approach to data collection and a statistical analysis based in logistic regression, only differences in referral for psychological testing were identified. Application of this method based on local demographics and culture may prove useful for institutions interested in evaluating racial influences on forensic outcomes., (© 2023 American Academy of Psychiatry and the Law.)
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- 2023
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10. Use of a Water Filter at Home Reduces Sugary Drink Consumption among Parents and Infants/Toddlers in a Predominantly Hispanic Community: Results from the Water Up!@ Home Intervention Trial.
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Reese AC, Burgos-Gil R, Cleary SD, Lora K, Rivera I, Gittelsohn J, Seper S, Monge-Rojas R, and Colón-Ramos U
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- Child, Preschool, Humans, Infant, Beverages, Hispanic or Latino, Parents, United States, Water, Sugar-Sweetened Beverages
- Abstract
Background: Water is recommended as an alternative for sugar-sweetened beverages (SSBs). Low-income, minority groups in the United States continue to exhibit high SSB and low water consumption, and are more likely to exceed 100% fruit juice recommendations., Objective: To test the effects of a home-based intervention designed to replace SSBs with tap water and reduce excess juice consumption among parents and their infants/toddlers., Design: Randomized controlled trial., Participants: Parents (n = 92) of infants/toddlers who participated in three Early Head Start home-visiting programs that serve predominantly Hispanic, low-income communities during 2019-2021., Intervention: The 12-week intervention (Water Up!@Home) simultaneously addressed physical barriers to tap water consumption (via a water filter) and sociocultural barriers to replacing SSBs and juice with water (via a curriculum). Comparison group received a water filter only. We hypothesized that the intervention would lead to a reduction of 6 fl oz/d in SSB and juice consumption., Main Outcomes: Parent-reported self and infant/toddler SSBs, water (filtered, tap, or bottled), and 100% fruit juice consumption., Statistical Analyses: Analysis of covariance to compare changes in consumption between experimental groups was performed. We also conducted t tests to assess changes within groups., Results: Participants in both groups reported significant reductions in SSBs from baseline (parents: intervention [-11.2 fl oz/d; P < 0.01]; comparison [-8.0 fl oz/d; P < 0.01]; children: intervention [-1.50 fl oz/d; P = 0.03]; comparison [-1.56 fl oz/d; P = 0.02]), increased water consumption (parents in both groups [+5.6 fl oz/d]; children: intervention [+3.61 fl oz/d; P = 0.01], comparison [+2.24 fl oz/d; P = 0.05]), mostly from filtered tap water. Differences between groups were not statistically significant. Intervention participants reported significant reductions in 100% fruit juice vs comparison (parents: -3.6 fl oz/d vs -1.0 fl oz/d; P < 0.01; children: -0.73 fl oz/d vs +0.48 fl oz/d; P = .03)., Conclusions: The intervention effectively reduced 100% fruit juice consumption. Water security should be examined as a contributor to SSB consumption in this population., (Copyright © 2023 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
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11. Distinguishing lone from group actor terrorists: A comparison of attitudes, ideologies, motivations, and risks.
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Dhumad S, Candilis PJ, Cleary SD, Dyer AR, and Khalifa NR
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- Humans, Male, Cross-Sectional Studies, Risk Factors, Motivation, Terrorism psychology, Group Dynamics
- Abstract
The increasing recognition of the risks posed by lone-actor terrorists provides the impetus for understanding the psychosocial and ideological characteristics that distinguish lone from group actors. This study examines differences between lone and group actor terrorists in two domains: (i) attitudes toward terrorism, ideology, and motivation for terrorist acts; and (ii) empirically derived risk factors for terrorism. Using a cross-sectional research design and primary source data from 160 men convicted of terrorism in Iraq, this study applied bivariate and logistic regression analyses to assess group differences. It tested the hypothesis that there are no statistically significant differences between the groups. Bivariate analyses revealed that lone actors were less likely than group actors, to be unemployed, to cite personal or group benefit as the main motives for terrorist activity, and to believe that acts of terrorism achieved their goals. Regression analysis indicated that having an authoritarian father was the only factor that significantly predicted group membership, with group actors three times more likely to report this trait. Lone actors and group actors are almost indistinguishable except for certain differences in attitudes, motives, employment, and having an authoritarian father., (© 2022 American Academy of Forensic Sciences.)
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- 2023
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12. How providing a low-cost water filter pitcher led Latino parents to reduce sugar-sweetened beverages and increase their water intake: explanatory qualitative results from the Water Up!@Home intervention trial.
- Author
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Santillán-Vázquez C, Hernández L, Reese AC, Burgos-Gil R, Cleary SD, Rivera IM, Gittelsohn J, Edberg MC, Monge-Rojas R, and Colón-Ramos U
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- Beverages, Drinking, Hispanic or Latino, Humans, Parents, Drinking Water, Sugar-Sweetened Beverages
- Abstract
Objective: This study sought to explain results of the Water Up!@Home randomised controlled trial where low-income parents were randomised to receive an educational intervention +a low-cost water filter pitcher or only the filter. Parents in both groups had reported statistically significant reductions in sugar-sweetened beverages (SSB) and increases in water intake post-intervention., Design: Qualitative explanatory in-depth interviews analysed thematically and deductively., Setting: Washington, DC metropolitan area, USA., Participants: Low-income Latino parents of infants/toddlers who had participated in the Water Up! @Home randomised controlled trial., Results: The filter-stimulated water consumption in both groups by (1) increasing parents' perception of water safety; (2) acting as a cue to action to drink water; (3) improving the flavour of water (which was linked to perceptions of safety) and (4) increasing the perception that this option was more economical than purchasing bottled water. Safe and palatable drinking water was more accessible and freely available in their homes; participants felt they did not need to ration their water consumption as before. Only intervention participants were able to describe a reduction in SSB intake and described strategies, skills and knowledge gained to reduce SSB intake. Among the comparison group, there was no thematic consensus about changes in SSB or any strategies or skills to reduce SSB intake., Conclusions: A low-cost water filter facilitated water consumption, which actively (or passively for comparison group) displaced SSB consumption. The findings have implications for understanding and addressing the role of water security on SSB consumption.
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- 2022
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13. The Adelante project: Realities, challenges and successes in addressing health disparities among central American immigrant youth.
- Author
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Edberg MC, Cleary SD, Andrade EL, Evans WD, Quinteros-Grady L, Alvayero RD, and Gonzalez A
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- Adolescent, Central America, Female, Hispanic or Latino, Humans, Internet, Pregnancy, Sexual Behavior, Emigrants and Immigrants, Substance-Related Disorders prevention & control
- Abstract
Objective: The Adelante intervention, implemented between 2013 and 2018, addressed an important syndemic health disparity for Central American immigrant youth approaching or in high school-the co-occurrence of substance abuse, sex risk (pregnancy, sexually transmitted infections, HIV), and interpersonal violence. Adelante was implemented and evaluated by the Avance Center for the Advancement of Immigrant/Refugee Health, which built on a university-community partnership that has been in place since 2005. Using a tailored, ecological positive youth development (PYD) approach, Adelante employed intervention strategies across ecological levels, including individual, family, peer, and community levels, with the use of social marketing and digital media strategies to link activities under one aspirational identity and support community engagement., Method: Using a Community Based Participatory Research approach with multiple community partners involved in the effort, the research assessed changes in co-occurring behavioral outcomes and tested hypotheses concerning relationships between PYD mediators and these outcomes. Multiple methods were used in collaboration with partners to assess intervention inputs and outcomes-detailed implementation process records; prepost surveys to assess changes in PYD assets, risk behavior knowledge, and prevention skills; a community survey in the intervention and comparison communities (total N = 3,600) at baseline and two follow-up waves; surveys of a high risk cohort ( n = 238) at baseline and follow-up; and social marketing campaign surveys ( n = 1,549) at baseline with 2 follow-up waves., Results: Analysis showed multiple improvements in PYD mediators and risk behavior outcomes, including an overall 70% increase in knowledge and a 15% increase in prevention skills. Preliminary analysis of risk behavior outcomes demonstrated, for example, a significant, inverse effect on reported sexual activity (past 3 months) for both Adelante intervention community and cohort samples. In addition, self-reported exposure to the social marketing campaign was associated with positive effects on multiple outcomes, including drug use risk and violence attitudes, and improvement in violence/sexual risk behavior outcomes in the intervention versus comparison community., Conclusion: There are few models in the literature that provide a roadmap for how to address multiple, related health conditions in marginalized, immigrant communities, even as most health disparities are associated with complex social ecologies. The Adelante intervention adds a useful model of this nature to the evidence base, and provides support for the ecological approach to PYD with respect to such communities. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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- 2022
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14. Ethics Oversight in Psychiatry: Data from a Model of Organizational Monitoring.
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Hume M, Hobart K, Briz L, Amara S, Cleary SD, and Candilis PJ
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- Humans, United States, Psychiatry, Societies, Medical
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Hallmarks of professions include self-regulation. The American Psychiatric Association fulfills this responsibility by delegating the handling of ethics complaints against members to each of 72 District Branches (DBs). The authors sought to explore the number and typology of ethics complaints received by member DBs, the handling of complaints, the relationship between the DB and state licensing authorities, the challenges and resources needed for conducting complaints, and the overall attitude of DBs regarding ethics review. This analysis presents the results of the survey and outlines how the process may be useful for professional medical organizations adhering to principles of transparency and empirically informed policy., (Copyright © 2021 Elsevier Inc. All rights reserved.)
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- 2021
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15. Using a Community-Based Participatory Mixed Methods Research Approach to Develop, Evaluate, and Refine a Nutrition Intervention to Replace Sugary Drinks with Filtered Tap Water among Predominantly Central-American Immigrant Families with Infants and Toddlers: The Water Up @Home Pilot Evaluation Study.
- Author
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McCarley S, López-Ríos M, Burgos Gil R, Turner MM, Cleary SD, Edberg M, and Colón-Ramos U
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- Adolescent, Adult, Aged, Central America ethnology, Child, Preschool, Filtration, Humans, Infant, Middle Aged, Parents, Pilot Projects, United States, Young Adult, Community-Based Participatory Research methods, Drinking Water administration & dosage, Emigrants and Immigrants statistics & numerical data, Hispanic or Latino statistics & numerical data, Program Evaluation methods, Sugar-Sweetened Beverages
- Abstract
Descriptions of the implementation of community-based participatory mixed-methods research (CBPMMR) in all phases of the engagement approach are limited. This manuscript describes the explicit integration of mixed-methods in four stages of CBPR: (1) connecting and diagnosing, (2) prescribing-implementing, (3) evaluating, and (4) disseminating and refining an intervention that aimed to motivate Latino parents (predominantly Central American in the US) of infants and toddlers to replace sugary drinks with filtered tap water. CBPMMR allowed for co-learning that led to the identification of preliminary behavioral outcomes, insights into potential mechanisms of behavior change, and revisions to the intervention design, implementation and evaluation.
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- 2021
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16. Factors influencing adjudicative competence and length of time to restoration.
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Secarea CM, Cleary SD, and Candilis PJ
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- Adolescent, Adult, Female, Hospitals, Psychiatric, Humans, Insanity Defense, Male, Middle Aged, Psychotherapy, Retrospective Studies, Young Adult, Institutionalization, Mental Competency, Mental Disorders therapy
- Abstract
Few studies on adjudicative competence explore the relationship between diagnosis, treatment, and restorability. Most focus on demographics and major psychiatric diagnosis with very few exploring the diagnoses common to the forensic population (i.e., personality disorders and substance abuse). Our study of 365 defendants who were incompetent to stand trial at a state psychiatric facility indicates that non-restored defendants have a greater likelihood of cognitive disorders, misdemeanor charges, and histories of prior hospitalization, and less likelihood of personality disorders. In addition, the odds of having a substance use disorder and being medication non-adherent was greater among restored defendants. The mean length of time to restoration (LOR) of 56 days was significantly different from the mean length of time to adjudication (LOA) for those not restored (88 days). This study supports prior literature on restorability while distinguishing those treated for psychosis from those treated for substance use and personality disorder. In its novel focus on medication adherence, the study expands the remediable factors available to clinical and forensic professionals and supports interventions that improve treatment and shorten the time to restoration., (© 2021 American Academy of Forensic Sciences.)
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- 2021
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17. Toward Understanding Youth Athletes' Fun Priorities: An Investigation of Sex, Age, and Levels of Play.
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Visek AJ, Mannix H, Chandran A, Cleary SD, McDonnell KA, and DiPietro L
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Colloquial conjecture asserts perceptions of difference in what is more or less important to youth athletes based on binary categorization, such as sex (girls vs. boys), age (younger vs. older), and level of competitive play (recreational vs. travel). The fun integration theory's FUN MAPS, which identify 11 fun-factors comprised of 81 fun-determinants, offers a robust framework from which to test these conceptions related to fun. Therefore, the purposes of this study were to scientifically explore: (a) the extent to which soccer players' prioritization of the 11 fun-factors and 81 fun-determinants were consistent with the gender differences hypothesis or the gender similarities hypothesis, and (b) how their fun priorities evolved as a function of their age and level of play. Players' ( n = 141) data were selected from the larger database that originally informed the conceptualization of the fun integration theory's FUN MAPS. Following selection, innovative pattern match displays and go-zone displays were produced to identify discrete points of consensus and discordance between groups. Regardless of sex, age, or level of play, results indicated extraordinarily high consensus among the players' reported importance of the fun-factors ( r = .90-.97) and fun-determinants ( r = .92-.93), which were consistently grouped within strata of primary, secondary, and tertiary importance. Overall, results were consistent with the gender similarities hypothesis, thereby providing the first data to dispel common conceptions about what is most fun with respect to sex, in addition to age and level of play, in a sample of youth soccer players.
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- 2020
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18. E-cigarettes and smoking cessation: a prospective study of a national sample of pregnant smokers.
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Chiang SC, Abroms LC, Cleary SD, Pant I, Doherty L, and Krishnan N
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- Adult, Female, Follow-Up Studies, Humans, Longitudinal Studies, Odds Ratio, Pregnancy, Pregnancy Complications psychology, Prevalence, Prospective Studies, Smoking Cessation psychology, Text Messaging, Treatment Outcome, Vaping psychology, Pregnancy Complications epidemiology, Pregnancy Complications therapy, Smoking Cessation methods, Vaping epidemiology, Vaping therapy
- Abstract
Background: Smoking during pregnancy has adverse health consequences for the mother and fetus. E-cigarettes could aid with smoking cessation but there is limited research on the prevalence and patterns of e-cigarette use, and their association with smoking cessation among pregnant smokers., Methods: We conducted a secondary analysis of a randomized controlled trial of a text-messaging program for smoking cessation among a U.S. national cohort of pregnant smokers (n = 428). Outcomes assessed were trajectories of e-cigarettes use from baseline to one-month follow-up, and longitudinal association between e-cigarette use at baseline and smoking cessation at one-month follow-up., Results: At baseline, 74 (17.29%) pregnant smokers used e-cigarettes in the past 30 days and 36 (8.41%) used e-cigarettes in the past 7 days. The primary reason stated for using e-cigarettes during pregnancy was for quitting. E-cigarette use between baseline and 1-month was inconsistent. Of 36 dual-users at baseline, 20 (55.56%) stopped using e-cigarettes by the 1-month follow-up and 14 initiated e-cigarette use. There was no evidence of an association between e-cigarette use at baseline and the primary smoking cessation outcome, 7-day point prevalence abstinence [adjusted odds ratio = 0.79, 95% confidence intervals = 0.33-1.92]., Conclusions: A secondary analysis of a national sample of pregnant smokers indicates that use of e-cigarettes is inconsistent and is not associated with improved smoking cessation outcomes. There is an urgent need to further examine the risk and benefits of e-cigarette use, especially during pregnancy.
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- 2019
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19. Factor structure of the Cannabis Experiences Questionnaire in a first-episode psychosis sample.
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Birnbaum ML, Cleary SD, Ramsay Wan C, Pauselli L, and Compton MT
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- Adolescent, Adult, Factor Analysis, Statistical, Female, Humans, Male, Young Adult, Marijuana Smoking psychology, Psychotic Disorders psychology, Surveys and Questionnaires statistics & numerical data
- Abstract
Aim: The Cannabis Experiences Questionnaire (CEQ) was developed to measure the subjective experiences of cannabis use both during and after intoxication. Despite the need to better understand the nature of the complex and significant relationship between cannabis use and early psychosis, this questionnaire has rarely been used in individuals with first-episode psychosis., Methods: We conducted a set of factor analyses using CEQ data from 194 first-episode psychosis patients who used cannabis in order to uncover the underlying factor structure of the questionnaire and thus the overarching types of psychological experiences during/after using cannabis in young people with psychotic disorders., Results: Our exploratory factor analysis identified 4 subscales, including: Distortions of Reality and Self-Perception (Factor 1), Euphoria Effects (Factor 2), Slowing and Amotivational Effects (Factor 3), and Anxiety and Paranoia Effects (Factor 4)., Conclusions: Elucidating the underlying factor structure of the CEQ in first-episode psychosis samples could help researchers move towards a deeper understanding of the types of experiences associated with cannabis intoxication among young adults with first-episode psychosis and could inform the development of programs designed to reduce use, improve the course of illness, and possibly delay or prevent the onset of psychotic symptoms in those at risk., (© 2017 John Wiley & Sons Australia, Ltd.)
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- 2019
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20. Strategies to Increase Latino Immigrant Youth Engagement in Health Promotion Using Social Media: Mixed-Methods Study.
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Andrade EL, Evans WD, Barrett N, Edberg MC, and Cleary SD
- Abstract
Background: Generating participant engagement in social media applications for health promotion and disease prevention efforts is vital for their effectiveness and increases the likelihood of effecting sustainable behavior change. However, there is limited evidence regarding effective strategies for engaging Latino immigrant youth using social media. As part of the Avance Center for the Advancement of Immigrant/Refugee Health in Washington, DC, USA, we implemented Adelante, a branded primary prevention program, to address risk factors for co-occurring substance use, sexual risk, and interpersonal violence among Latino immigrant adolescents aged 12 to 19 years in a Washington, DC suburb., Objective: The objectives of this study were to (1) characterize Adelante participant Facebook reach and engagement and (2) identify post content and features that resulted in greater user engagement., Methods: We established the Adelante Facebook fan page in October of 2013, and the Adelante social marketing campaign used this platform for campaign activities from September 2015 to September 2016. We used Facebook Insights metrics to examine reach and post engagement of Adelante Facebook page fans (n=743). Data consisted of Facebook fan page posts between October 1, 2013 and September 30, 2016 (n=871). We developed a 2-phased mixed-methods analytical plan and coding scheme, and explored the association between post content categories and features and a composite measure of post engagement using 1-way analysis of variance tests. P<.05 determined statistical significance., Results: Posts on the Adelante Facebook page had a total of 34,318 clicks, 473 comments, 9080 likes or reactions, and 617 shares. Post content categories that were statistically significantly associated with post engagement were Adelante program updates (P<.001); youth achievement showcases (P=.001); news links (P<.001); social marketing campaign posts (P<.001); and prevention topics, including substance abuse (P<.001), safe sex (P=.02), sexually transmitted disease prevention (P<.001), and violence or fighting (P=.047). Post features that were significantly associated with post engagement comprised the inclusion of photos (P<.001); Spanish (P<.001) or bilingual (P=.001) posts; and portrayal of youth of both sexes (P<.001) portrayed in groups (P<.001) that were facilitated by adults (P<.001)., Conclusions: Social media outreach is a promising strategy that youth programs can use to complement in-person programming for augmented engagement. The Latino immigrant youth audience in this study had a tendency toward more passive social media consumption, having implications for outreach strategies and engagement measurement in future studies. While study findings confirmed the utility of social marketing campaigns for increasing user engagement, findings also highlighted a high level of engagement among youth with posts that covered casual, day-to-day program activity participation. This finding identifies an underexplored area that should be considered for health messaging, and also supports interventions that use peer-to-peer and user-generated health promotion approaches., (©Elizabeth Louise Andrade, W Douglas Evans, Nicole Barrett, Mark Cameron Edberg, Sean D Cleary. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 19.12.2018.)
- Published
- 2018
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21. Perceived importance of the fun integration theory's factors and determinants: A comparison among players, parents, and coaches.
- Author
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Visek AJ, Mannix H, Chandran A, Cleary SD, McDonnell K, and DiPietro L
- Abstract
Conceptualized by youth soccer players, parents, and coaches, the fun integration theory's FUN MAPS identify 11 fun-factors and 81 fun-determinants. The purpose of this study was to conduct a secondary analysis of those data to explore the extent to which the parents (responsible for supporting) and the coaches (tasked with delivering soccer programs) perceived importance of the factors and determinants were congruent with the players' self-reported importance. We produced pattern-match displays and go-zone displays, which are innovative, visual representations of group comparisons that are unique to concept-mapping methods, to determine the overall consensus between the groups, in addition to identifying exact points of agreement and disagreement. Results indicated congruence between parents and players was extraordinarily high ( r = 0.89-0.93) and significantly more congruent than coaches and players ( r = 0.75-0.84). Results also indicated consensus was significantly lower among adolescent players and coaches ( r = 0.66-0.71) compared to younger players and coaches ( r = 0.77-0.90). Disparities in the perceived importance of specific fun-factors and fun-determinants between groups are discussed. In addition, transformative learning theory is introduced as an immersive approach to developing fun schemas consistent with the youth athletes' fun ethos that will enable coaches to be athlete-centric when creating fun, positive sport experiences for youth., Competing Interests: Declaration of Conflicting Interests The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
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- 2018
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22. Immigrant Trauma and Mental Health Outcomes Among Latino Youth.
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Cleary SD, Snead R, Dietz-Chavez D, Rivera I, and Edberg MC
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- Adolescent, Anxiety ethnology, Child, Comorbidity, Depression ethnology, Female, Hispanic or Latino, Humans, Male, Regression Analysis, Socioeconomic Factors, Stress Disorders, Post-Traumatic ethnology, United States epidemiology, Emigrants and Immigrants psychology, Emigration and Immigration statistics & numerical data, Mental Health ethnology, Psychological Trauma ethnology, Violence psychology
- Abstract
While research has demonstrated an association between trauma and mental health, this study examined the association between trauma experienced premigration, during migration, and postmigration, and current mental health status among Latino youth aged 12-17 years old living in the US for < 3 years. Participants reported traumatic events experienced in their home country, during migration, and after settling in the US. Regression models examined trauma experienced at each stage of the migration process predicting current levels of depression, anxiety, and post-traumatic stress disorder. Two-thirds of youth experienced at least one traumatic event, 44% experienced an event once, and 23% experienced two or more traumatic events during migration. Trauma experienced at different migration stages was associated with distinctive mental health outcomes. It is essential that access to culturally sensitive assessment and treatment services be available to ensure transition to a healthy adulthood.
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- 2018
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23. The aprosody of schizophrenia: Computationally derived acoustic phonetic underpinnings of monotone speech.
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Compton MT, Lunden A, Cleary SD, Pauselli L, Alolayan Y, Halpern B, Broussard B, Crisafio A, Capulong L, Balducci PM, Bernardini F, and Covington MA
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- Adult, Female, Humans, Male, Phonetics, Psychotic Disorders complications, Schizophrenia complications, Speech Disorders etiology, Psycholinguistics methods, Psychotic Disorders physiopathology, Schizophrenia physiopathology, Speech Acoustics, Speech Disorders diagnosis, Speech Disorders physiopathology, Speech Production Measurement methods
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Objective: Acoustic phonetic methods are useful in examining some symptoms of schizophrenia; we used such methods to understand the underpinnings of aprosody. We hypothesized that, compared to controls and patients without clinically rated aprosody, patients with aprosody would exhibit reduced variability in: pitch (F0), jaw/mouth opening and tongue height (formant F1), tongue front/back position and/or lip rounding (formant F2), and intensity/loudness., Methods: Audiorecorded speech was obtained from 98 patients (including 25 with clinically rated aprosody and 29 without) and 102 unaffected controls using five tasks: one describing a drawing, two based on spontaneous speech elicited through a question (Tasks 2 and 3), and two based on reading prose excerpts (Tasks 4 and 5). We compared groups on variation in pitch (F0), formant F1 and F2, and intensity/loudness., Results: Regarding pitch variation, patients with aprosody differed significantly from controls in Task 5 in both unadjusted tests and those adjusted for sociodemographics. For the standard deviation (SD) of F1, no significant differences were found in adjusted tests. Regarding SD of F2, patients with aprosody had lower values than controls in Task 3, 4, and 5. For variation in intensity/loudness, patients with aprosody had lower values than patients without aprosody and controls across the five tasks., Conclusions: Findings could represent a step toward developing new methods for measuring and tracking the severity of this specific negative symptom using acoustic phonetic parameters; such work is relevant to other psychiatric and neurological disorders., (Copyright © 2018 Elsevier B.V. All rights reserved.)
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- 2018
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24. Computational linguistic analysis applied to a semantic fluency task to measure derailment and tangentiality in schizophrenia.
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Pauselli L, Halpern B, Cleary SD, Ku BS, Covington MA, and Compton MT
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- Adult, Cognition physiology, Cognition Disorders diagnosis, Cognition Disorders psychology, Female, Humans, Male, Middle Aged, Reproducibility of Results, Young Adult, Linguistics, Proof of Concept Study, Schizophrenia diagnosis, Schizophrenic Psychology, Semantics, Thinking physiology
- Abstract
Although rating scales to assess formal thought disorder exist, there are no objective, high-reliability instruments that can quantify and track it. This proof-of-concept study shows that CoVec, a new automated tool, is able to differentiate between controls and patients with schizophrenia with derailment and tangentiality. According to ratings from the derailment and tangentiality items of the Scale for the Assessment of Positive Symptoms, we divided the sample into three groups: controls, patients without formal thought disorder, and patients with derailment/tangentiality. Their lists of animals produced during a one-minute semantic fluency task were processed using CoVec, a newly developed software that measures the semantic similarity of words based on vector semantic analysis. CoVec outputs were Mean Similarity, Coherence, Coherence-5, and Coherence-10. Patients with schizophrenia produced fewer words than controls. Patients with derailment had a significantly lower mean number of words and lower Coherence-5 than controls and patients without derailment. Patients with tangentiality had significantly lower Coherence-5 and Coherence-10 than controls and patients without tangentiality. Despite the small samples of patients with clinically apparent thought disorder, CoVec was able to detect subtle differences between controls and patients with either or both of the two forms of disorganization., (Copyright © 2018 Elsevier B.V. All rights reserved.)
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- 2018
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25. Development of the place-based Adelante social marketing campaign for prevention of substance use, sexual risk and violence among Latino immigrant youth.
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Andrade EL, Evans WD, Barrett ND, Cleary SD, Edberg MC, Alvayero RD, Kierstead EC, and Beltran A
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- Adolescent, Central America ethnology, Child, Female, Focus Groups, Humans, Male, Maryland, Social Media, Young Adult, Emigrants and Immigrants, Health Promotion methods, Hispanic or Latino, Sexual Behavior, Social Marketing, Substance-Related Disorders prevention & control, Violence prevention & control
- Abstract
Immigrant Latino youth represent a high-risk subgroup that should be targeted with health promotion efforts. However, there are considerable barriers to engagement in health-related programming. Little is known about the engagement possibilities of social marketing campaigns and digital strategies for traditionally 'hard-to-reach' immigrants, underscoring the importance of testing these techniques with immigrant Latino adolescents. We developed and piloted a place-based social marketing campaign in coordination with the branded, Positive Youth Development-based (PYD) Adelante intervention targeting risk factors for co-occurring youth substance abuse, sexual risk and violence. Building on prior research, we conducted a four-phase formative research process, and planned the Adelante social marketing campaign based on findings from one group interview and ongoing consultation with Adelante staff (n=8) and four focus groups with youth (n=35). Participants identified four overarching campaign themes, and suggested portrayal of resilient, proud youth who achieved goals despite adversity. Youth guided selection of campaign features and engagement strategies, including message/visual content, stylistic elements, and a mixed language approach. We developed a 12-month campaign to be delivered via print ads, multi-platform social media promotion, contests, youth-generated videos, blog posts, and text messaging. We describe the process and outcome of campaign development and make recommendations for future campaigns.
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- 2018
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26. The Mediating Effect of Adelante brand equity on Latino Immigrant Positive Youth Development Outcomes.
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Evans WD, Andrade EL, Barrett ND, Cleary SD, Snider J, and Edberg M
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- Acculturation, Adaptation, Psychological, Adolescent, Female, Humans, Male, Parent-Child Relations, Poverty, Safe Sex, Social Support, Substance-Related Disorders prevention & control, Violence prevention & control, Adolescent Behavior, Emigrants and Immigrants psychology, Health Promotion methods, Hispanic or Latino psychology, Psychology, Adolescent, Social Marketing
- Abstract
This paper reports on mediation analysis of effects of the Adelante brand, an innovative program for Latino immigrant adolescents and their families, and positive youth development (PYD) outcomes. Specific objectives were to increase adolescent engagement and participation in a community-based program called Adelante, based on PYD theory, which sought to reduce substance use, sexual risk taking, and interpersonal violence among Latino immigrant youth. A total of 238 parent-child dyads were recruited from a predominantly low-income Latino immigrant community and followed for an average of 22 months. Measures included demographics; acculturation; stress and coping; social support; violence, substance use, and sexual risk attitudes; future expectations; the Adelante brand equity scale; and PYD asset measures. Multiple regression modeling shows that the leadership brand equity construct is associated with decreased proviolence and increased antiviolence attitudes. Additionally, having any program exposure (vs. none) is associated with improved substance abuse attitudes in models adjusting for the loyalty brand equity construct. In mediation analysis, we observed a mediating effect of the leadership brand equity construct on improved antiviolence attitudes among those exposed to the Adelante program. As found in previous research, Adelante brand equity operated as a mediator of program effects on Latino youth PYD outcomes.
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- 2018
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27. A Randomized Trial of Text Messaging for Smoking Cessation in Pregnant Women.
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Abroms LC, Johnson PR, Leavitt LE, Cleary SD, Bushar J, Brandon TH, and Chiang SC
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- Adult, Age Factors, Female, Follow-Up Studies, Health Promotion methods, Humans, Intention to Treat Analysis, Postpartum Period, Pregnancy, Pregnancy Trimesters, Pregnant Women psychology, Saliva chemistry, Smoking epidemiology, Time Factors, Young Adult, Smokers psychology, Smoking Cessation methods, Smoking Prevention methods, Text Messaging
- Abstract
Introduction: There is a need for innovation in both the enrollment of pregnant smokers in smoking cessation treatment programs and in the types of treatments offered. The study tests whether an interactive and intensive text messaging program, Quit4baby, can promote smoking cessation for pregnant women already enrolled in a health text messaging program, Text4baby., Methods: Between July 2015 and February 2016, a total of 35,957 recruitment text messages were sent to Text4baby subscribers. Eligible pregnant smokers were enrolled and randomized to receive Text4baby (control) or Text4baby and Quit4baby (intervention; N=497). Participants were surveyed at 1 month, 3 months, and 6 months post-enrollment, and saliva samples were collected at 3 months for biochemical verification of smoking status. Data were collected from 2015 to 2016 and analyzed in 2016., Results: Using an intention-to-treat analysis, 28.80% of the intervention group and 15.79% of the control group reported not smoking in the past 7 days at 1 month (p<0.01), and 35.20% of the intervention group and 22.67% of the control group reported not smoking in the past 7 days at 3 months (p<0.01). Biochemical verification of smoking status at 3 months indicated no significant differences between groups (15.60% in the intervention group and 10.93% in the control group [p=0.13]), although significant differences favoring the intervention were found for older smokers (p<0.05) and for those who enrolled in their second or third trimester of pregnancy (p<0.05). Self-report of late pregnancy 7- and 30-day point prevalence abstinence favored the intervention group (p<0.001, p<0.01). No significant differences were observed at the 6-month follow-up or in the postpartum period., Conclusions: Results provide limited support of the efficacy of the Quit4baby text messaging program in the short term and late in pregnancy, but not in the postpartum period., (Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.)
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- 2017
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28. Applying Ecological Positive Youth Development Theory to Address Co-Occurring Health Disparities Among Immigrant Latino Youth.
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Edberg MC, Cleary SD, Andrade EL, Evans WD, Simmons LK, and Cubilla-Batista I
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- Adolescent, Adolescent Development, Cooperative Behavior, Family Relations, Humans, Leadership, Sexual Behavior ethnology, Sexual Health, Substance-Related Disorders ethnology, Violence ethnology, Emigrants and Immigrants, Health Promotion organization & administration, Health Status Disparities, Hispanic or Latino, Social Environment
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This article outlines the theory and resulting approach employed in a multilevel, integrated, collaborative community intervention called Adelante, implemented by a university-community partnership in a Latino immigrant community to address co-occurring health disparities of substance abuse, sex risk, and interpersonal violence among youth. The basis for the intervention is a social-ecological interpretation of positive youth development theory, which focuses on changes in the person environment context and community assets as a preventive mechanism. This approach is viewed as appropriate for a community facing multiple barriers to health equity. The article describes the translation of this positive youth development model to practice, including the design of the intervention, intervention components, and the protocol for evaluation. The Adelante intervention is intended to reduce health disparities and, in addition, to add a broader community model to the evidence base.
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- 2017
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29. Recruiting pregnant smokers from Text4baby for a randomized controlled trial of Quit4baby.
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Leavitt L, Abroms L, Johnson P, Schindler-Ruwisch J, Bushar J, Singh I, Cleary SD, McInvale W, and Turner M
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- Adult, Emotions, Feasibility Studies, Female, Follow-Up Studies, Humans, Pregnancy, Pregnant Women psychology, Reward, Smokers psychology, Smoking psychology, Telephone, Patient Selection, Pregnancy Complications therapy, Smoking therapy, Smoking Cessation methods, Text Messaging
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Recruiting pregnant smokers into clinical trials is challenging since this population tends to be disadvantaged, the behavior is stigmatized, and the intervention window is limited. The purpose of this study is to test the feasibility and effectiveness of recruiting pregnant smokers into a smoking cessation trial by sending recruitment text messages to an existing subscriber list. Recruitment messages were sent to subscribers flagged as pregnant in Text4baby, a national text messaging program for pregnant women and mothers. Four recruitment messages were rotated to test the effectiveness of different emotional frames and a financial incentive. Study staff called subscribers who expressed interest to screen for eligibility and enroll eligible women. Between October 6, 2015 and February 2, 2016, 10,194 recruitment messages were sent to Text4baby subscribers flagged as pregnant, and 10.18% (1038) responded indicating interest. No significant increase in cancellation was observed compared to subscribers who received other ad hoc messages. Of respondents, 54.05% (561) were reached by phone for follow-up, and 21.97% (228) were found to be eligible. Among the eligible, 87% (199) pregnant smokers enrolled. The recruitment message with a pride emotional appeal had a significantly higher response (p = 0.02) compared to the recruitment message with no emotional appeal, but enrollment did not significantly differ between recruitment messages with different emotional appeals. The recruitment messages with a reference to financial incentive yielded higher response (p < 0.01) and enrollment (p = 0.03) compared to a recruitment message without. This study demonstrates success recruiting pregnant smokers using text message. Future studies should consider building on this approach for recruiting high-risk populations.
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- 2017
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30. Risk Prediction Models in Psychiatry: Toward a New Frontier for the Prevention of Mental Illnesses.
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Bernardini F, Attademo L, Cleary SD, Luther C, Shim RS, Quartesan R, and Compton MT
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- Anxiety Disorders diagnosis, Anxiety Disorders psychology, Bipolar Disorder diagnosis, Bipolar Disorder psychology, Depressive Disorder, Major diagnosis, Depressive Disorder, Major psychology, Humans, Likelihood Functions, Psychotic Disorders diagnosis, Psychotic Disorders psychology, Schizophrenia diagnosis, Stress Disorders, Post-Traumatic diagnosis, Stress Disorders, Post-Traumatic psychology, Anxiety Disorders epidemiology, Anxiety Disorders prevention & control, Bipolar Disorder epidemiology, Bipolar Disorder prevention & control, Depressive Disorder, Major epidemiology, Depressive Disorder, Major prevention & control, Psychotic Disorders epidemiology, Psychotic Disorders prevention & control, Risk Assessment statistics & numerical data, Schizophrenia epidemiology, Schizophrenia prevention & control, Schizophrenic Psychology, Stress Disorders, Post-Traumatic epidemiology, Stress Disorders, Post-Traumatic prevention & control
- Abstract
Objective: We conducted a systematic, qualitative review of risk prediction models designed and tested for depression, bipolar disorder, generalized anxiety disorder, posttraumatic stress disorder, and psychotic disorders. Our aim was to understand the current state of research on risk prediction models for these 5 disorders and thus future directions as our field moves toward embracing prediction and prevention., Data Sources: Systematic searches of the entire MEDLINE electronic database were conducted independently by 2 of the authors (from 1960 through 2013) in July 2014 using defined search criteria. Search terms included risk prediction, predictive model, or prediction model combined with depression, bipolar, manic depressive, generalized anxiety, posttraumatic, PTSD, schizophrenia, or psychosis., Study Selection: We identified 268 articles based on the search terms and 3 criteria: published in English, provided empirical data (as opposed to review articles), and presented results pertaining to developing or validating a risk prediction model in which the outcome was the diagnosis of 1 of the 5 aforementioned mental illnesses. We selected 43 original research reports as a final set of articles to be qualitatively reviewed., Data Extraction: The 2 independent reviewers abstracted 3 types of data (sample characteristics, variables included in the model, and reported model statistics) and reached consensus regarding any discrepant abstracted information., Results: Twelve reports described models developed for prediction of major depressive disorder, 1 for bipolar disorder, 2 for generalized anxiety disorder, 4 for posttraumatic stress disorder, and 24 for psychotic disorders. Most studies reported on sensitivity, specificity, positive predictive value, negative predictive value, and area under the (receiver operating characteristic) curve., Conclusions: Recent studies demonstrate the feasibility of developing risk prediction models for psychiatric disorders (especially psychotic disorders). The field must now advance by (1) conducting more large-scale, longitudinal studies pertaining to depression, bipolar disorder, anxiety disorders, and other psychiatric illnesses; (2) replicating and carrying out external validations of proposed models; (3) further testing potential selective and indicated preventive interventions; and (4) evaluating effectiveness of such interventions in the context of risk stratification using risk prediction models., (© Copyright 2017 Physicians Postgraduate Press, Inc.)
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- 2017
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31. Trends in the Incidence of Fatal Prostate Cancer in the United States by Race.
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Kelly SP, Rosenberg PS, Anderson WF, Andreotti G, Younes N, Cleary SD, and Cook MB
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- Age Factors, Aged, Health Status Disparities, Humans, Incidence, Male, Middle Aged, Prostatic Neoplasms epidemiology, SEER Program statistics & numerical data, Survival Analysis, United States epidemiology, Black or African American statistics & numerical data, Prostatic Neoplasms ethnology, Prostatic Neoplasms mortality, SEER Program trends, White People statistics & numerical data
- Abstract
Background: Prostate-specific antigen (PSA) testing has dramatically changed the composition of prostate cancer (PCa), making it difficult to interpret incidence trends. New methods are needed to examine temporal trends in the incidence of clinically significant PCa and whether trends vary by race., Objective: To conduct an in-depth analysis of incidence trends in clinically significant PCa, defined as cases in which PCa was the underlying cause of death within 10 yr of diagnosis., Design, Setting, and Participants: We extracted incident PCa cases during the period 1975-2002 and associated causes of death and survival through 2012 from nine cancer registries in the population-based Surveillance Epidemiology and End Results program database., Outcome Measurements and Statistical Analysis: We applied joinpoint regression analysis to identify when significant changes in trends occurred and age-period-cohort models to examine longitudinal and cross-sectional trends in the incidence of fatal PCa., Results and Limitations: Among 51 680 fatal PCa cases, incidence increased 1% per year prior to 1992, declined 15% per year from 1992 to 1995, and further declined by 5% per year through 2002. Age-specific incidence rates of fatal disease decreased >2% per year among men aged ≥60 yr, yet rates remained relatively stable among men aged ≤55 yr. Fatal disease rates were >2-fold higher in black men compared with white men, a racial disparity that increased to 4.2-fold among younger men., Conclusions: The incidence of fatal PCa substantially declined after widespread PSA screening and treatment advances. Nevertheless, rates of fatal disease among younger men have remained relatively stable, suggesting the need for additional attention to early onset PCa, especially among black men. The persistent black-to-white racial disparity observed in fatal PCa underscores the need for greater understanding of the causes of this difference so that strategies can be implemented to eliminate racial disparities., Patient Summary: We assessed how the incidence of ultimately fatal prostate cancer (PCa) changed over time. We found that the incidence of fatal PCa declined by >50% since the introduction of prostate-specific antigen testing and advances in treatment options; however, incidence rates among younger men remained relatively stable, and younger black men exhibited a 4.2-fold higher risk for fatal disease compared with white men., (Published by Elsevier B.V.)
- Published
- 2017
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32. Determinants of Light and Intermittent Smoking in the United States: Results from Three Pooled National Health Surveys.
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Reyes-Guzman CM, Pfeiffer RM, Lubin J, Freedman ND, Cleary SD, Levine PH, and Caporaso NE
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- Adolescent, Adult, Female, Humans, Incidence, Male, Middle Aged, Odds Ratio, Prevalence, Retrospective Studies, Smoking ethnology, Socioeconomic Factors, United States epidemiology, Young Adult, Ethnicity, Health Surveys methods, Nutrition Surveys methods, Racial Groups, Smoking adverse effects, Tobacco Use Disorder ethnology
- Abstract
Background: Light and/or intermittent smokers have been the fastest growing segment of cigarette smokers in the United States over the past two decades. Defining their behavioral characteristics is a critical public health priority., Methods: Our sample included 78,229 U.S. adults from three pooled contemporary population-based surveys: the 2012 NHIS, 2012 NSDUH, and 2011-2012 NHANES. We classified current smokers into four categories (light and intermittent [LITS], light-daily, heavier-intermittent, and heavier-daily) and assessed smoking behaviors, illicit drug use, and mental health indicators using weighted analyses., Results: Analyses associated smoking categories with nicotine dependence, age of smoking initiation, race/ethnicity, and other demographic and behavioral factors. Compared with heavier-daily smokers, smokers who were LITS were most likely to have mild or no nicotine dependence (weighted odds ratio [OR], 16.92; 95% confidence interval [CI], 13.10-21.85), to start smoking cigarettes regularly after age 21 (OR, 3.42; 95% CI, 2.84-4.12), and to be Hispanic (OR, 5.38; 95% CI, 4.38-6.61). Additional significant results were found for other categories of smokers., Conclusions: Based on pooled data from three large national surveys, light and/or intermittent smokers differed in smoking, drug use, and mental health behaviors from heavier-daily, former, and never smokers. Notable differences by level of smoking frequency and intensity were observed for nicotine dependence, age of smoking initiation, and race/ethnicity., Impact: Our results may help focus preventive measures and policies for the growing number of light and/or intermittent smokers in the United States because smoking patterns vary by behavioral and socioeconomic factors. Cancer Epidemiol Biomarkers Prev; 26(2); 228-39. ©2016 AACR., (©2016 American Association for Cancer Research.)
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- 2017
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33. Prediagnostic Body Mass Index Trajectories in Relation to Prostate Cancer Incidence and Mortality in the PLCO Cancer Screening Trial.
- Author
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Kelly SP, Graubard BI, Andreotti G, Younes N, Cleary SD, and Cook MB
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- Aged, Follow-Up Studies, Humans, Male, Mass Screening methods, Middle Aged, Obesity complications, Obesity metabolism, Proportional Hazards Models, Prospective Studies, Prostate-Specific Antigen blood, Risk Factors, Surveys and Questionnaires, Treatment Outcome, Body Mass Index, Early Detection of Cancer methods, Prostatic Neoplasms epidemiology, Prostatic Neoplasms mortality
- Abstract
Background: Evidence suggests that obesity in adulthood is associated with increased risk of "clinically significant" prostate cancer. However, studies of body mass index (BMI) across the adult life course and prostate cancer risks remain limited., Methods: In a prospective cohort of 69 873 men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined associations of prediagnostic BMI across the adult life course with risk of incident prostate cancer and fatal prostate cancer (prostate cancer-specific mortality). At 13 years of follow-up, we identified 7822 incident prostate cancer cases, of which 3078 were aggressive and 255 fatal. BMI trajectories were determined using latent-class trajectory modeling. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs)., Results: BMI at age 20 years, 50 years, and baseline questionnaire (mean age = 63 years) were associated with increased risks of fatal prostate cancer (HRs = 1.27-1.32 per five-unit increase). In five BMI trajectories identified, fatal prostate cancer risk was increased in men who had a normal BMI (HR = 1.95, 95% CI = 1.21 to 3.12) or who were overweight (HR = 2.65, 95% CI = 1.35 to 5.18) at age 20 years and developed obesity by baseline compared with men who maintained a normal BMI. Aggressive and nonaggressive prostate cancer were not associated with BMI, and modest inverse associations were seen for total prostate cancer., Conclusions: Our results suggest that BMI trajectories during adulthood that result in obesity lead to an elevated risk of fatal prostate cancer., (Published by Oxford University Press 2016. This work is written by US Government employees and is in the public domain in the US.)
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- 2016
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34. Male Pattern Baldness in Relation to Prostate Cancer-Specific Mortality: A Prospective Analysis in the NHANES I Epidemiologic Follow-up Study.
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Zhou CK, Levine PH, Cleary SD, Hoffman HJ, Graubard BI, and Cook MB
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- Adult, Aged, Humans, Male, Middle Aged, Nutrition Surveys, Prospective Studies, United States epidemiology, Alopecia epidemiology, Prostatic Neoplasms epidemiology
- Abstract
We used male pattern baldness as a proxy for long-term androgen exposure and investigated the association of dermatologist-assessed hair loss with prostate cancer-specific mortality in the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. From the baseline survey (1971-1974), we included 4,316 men who were 25-74 years of age and had no prior cancer diagnosis. We estimated hazard ratios and used Cox proportional hazards regressions with age as the time metric and baseline hazard stratified by baseline age. A hybrid framework was used to account for stratification and clustering of the sample design, with adjustment for the variables used to calculate sample weights. During follow-up (median, 21 years), 3,284 deaths occurred; prostate cancer was the underlying cause of 107. In multivariable models, compared with no balding, any baldness was associated with a 56% higher risk of fatal prostate cancer (hazard ratio = 1.56; 95% confidence interval: 1.02, 2.37), and moderate balding specifically was associated with an 83% higher risk (hazard ratio = 1.83; 95% confidence interval: 1.15, 2.92). Conversely, patterned hair loss was not statistically significantly associated with all-cause mortality. Our analysis suggests that patterned hair loss is associated with a higher risk of fatal prostate cancer and supports the hypothesis of overlapping pathophysiological mechanisms., (Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.)
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- 2016
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35. Racial and ethnic disparities in parent-reported diagnosis of ADHD: National Survey of Children's Health (2003, 2007, and 2011).
- Author
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Collins KP and Cleary SD
- Subjects
- Adolescent, Child, Child, Preschool, Female, Health Surveys, Humans, Male, Prevalence, Socioeconomic Factors, United States epidemiology, Attention Deficit Disorder with Hyperactivity epidemiology, Attention Deficit Disorder with Hyperactivity ethnology, Child Health trends, Ethnicity statistics & numerical data, Health Status Disparities, Parents psychology
- Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed mental disorder among children in the United States. While overall ADHD prevalence continues to rise, few have examined difference by race/ethnicity., Objective: To examine trends in parent-reported ADHD prevalence between 2003 and 2011 across racial/ethnic groups and the role of sociodemographic factors in observed differences in ADHD., Method: Data were from 3 waves of the National Survey of Children's Health (2003, 2007, and 2011), including 190,408 children aged 5-17 years. Independent variables included race/ethnicity (white non-Hispanic, black non-Hispanic, Hispanic, other non-Hispanic), gender, age, poverty level, primary language, insurance status, parental marital status, and neighborhood safety. Sociodemographic factors and year were compared among those diagnosed with ADHD and between racial/ethnic groups using χ(2) tests. Adjusted logistic regression models, stratified by race/ethnicity, were fit to examine the association between identified risk factors and ADHD across racial/ethnic groups. Parental report of an ADD or ADHD diagnosis for a child aged 5-17 years was the dependent variable. If the household included more than 1 child aged 5-17 years, 1 was selected at random., Results: Increasing trends were observed over the past decade in the prevalence of parent-reported ADHD overall (43%, P < .001), among children aged 10-14 years (47%, P < .001), and adolescents aged 15-17 years (52%, P < .001). Although the ADHD prevalence was still highest among whites, increasing trends were observed for all racial/ethnic groups, most notably among Hispanics, increasing 83% from 2003 to 2011 (P < .001). A greater increase in ADHD was also observed among females (55%, P < .001) than among males (40%)., Conclusions: Economics, family status, non-English language in the home, and neighborhood safety factors differentially impacted diagnosed ADHD across racial/ethnic groups. Although new insights into the role of economic, family, and neighborhood factors on parent-reported ADHD diagnoses were noted, more research is needed to understand causes of the observed racial/ethnic disparities., (© Copyright 2016 Physicians Postgraduate Press, Inc.)
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- 2016
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36. Racial Disparities in Pain Management of Children With Appendicitis in Emergency Departments.
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Goyal MK, Kuppermann N, Cleary SD, Teach SJ, and Chamberlain JM
- Subjects
- Adolescent, Adult, Child, Cross-Sectional Studies, Emergency Service, Hospital, Ethnicity, Female, Humans, Male, Practice Patterns, Physicians' statistics & numerical data, Young Adult, Analgesia statistics & numerical data, Analgesics therapeutic use, Appendicitis drug therapy, Healthcare Disparities statistics & numerical data, Pain Management
- Abstract
Importance: Racial disparities in use of analgesia in emergency departments have been previously documented. Further work to understand the causes of these disparities must be undertaken, which can then help inform the development of interventions to reduce and eradicate racial disparities in health care provision., Objective: To evaluate racial differences in analgesia administration, and particularly opioid administration, among children diagnosed as having appendicitis., Design, Setting, and Participants: Repeated cross-sectional study of patients aged 21 years or younger evaluated in the emergency department who had an International Classification of Diseases, Ninth Revision diagnosis of appendicitis, using the National Hospital Ambulatory Medical Care Survey from 2003 to 2010. We calculated the frequency of both opioid and nonopioid analgesia administration using complex survey weighting. We then performed multivariable logistic regression to examine racial differences in overall administration of analgesia, and specifically opioid analgesia, after adjusting for important demographic and visit covariates, including ethnicity and pain score., Main Outcomes and Measures: Receipt of analgesia administration (any and opioid) by race., Results: An estimated 0.94 (95% CI, 0.78-1.10) million children were diagnosed as having appendicitis. Of those, 56.8% (95% CI, 49.8%-63.9%) received analgesia of any type; 41.3% (95% CI, 33.7%-48.9%) received opioid analgesia (20.7% [95% CI, 5.3%-36.0%] of black patients vs 43.1% [95% CI, 34.6%-51.4%] of white patients). When stratified by pain score and adjusted for ethnicity, black patients with moderate pain were less likely to receive any analgesia than white patients (adjusted odds ratio = 0.1 [95% CI, 0.02-0.8]). Among those with severe pain, black patients were less likely to receive opioids than white patients (adjusted odds ratio = 0.2 [95% CI, 0.06-0.9]). In a multivariable model, there were no significant differences in the overall rate of analgesia administration by race. However, black patients received opioid analgesia significantly less frequently than white patients (12.2% [95% CI, 0.1%-35.2%] vs 33.9% [95% CI, 0.6%-74.9%], respectively; adjusted odds ratio = 0.2 [95% CI, 0.06-0.8])., Conclusions and Relevance: Appendicitis pain is undertreated in pediatrics, and racial disparities with respect to analgesia administration exist. Black children are less likely to receive any pain medication for moderate pain and less likely to receive opioids for severe pain, suggesting a different threshold for treatment.
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- 2015
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37. Brief Report: Increasing Acceptance of Homosexuality in the United States Across Racial and Ethnic Subgroups.
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Glick SN, Cleary SD, and Golden MR
- Subjects
- HIV Infections epidemiology, HIV Infections psychology, HIV Infections transmission, Humans, Male, Racial Groups, Risk Factors, United States, Homosexuality, Male psychology, Psychological Distance
- Abstract
After recent civil rights expansions for sexual minorities in the United States, we updated previous findings on population-level attitudes toward homosexuality measured in the General Social Survey. In 2014, 40.1% of respondents reported that homosexuality was "always wrong" compared with 54.8% in 2008 (P < 0.001). Although black and Hispanic respondents consistently reported more negative attitudes regarding homosexuality than white respondents throughout 2008 to 2014, the percentage declined among all racial/ethnic groups. Among MSM, more positive attitudes were associated with HIV testing. Research shows a potential association between homophobia and HIV risk; thus, these population-level changes may promote better health among MSM.
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- 2015
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38. Male pattern baldness in relation to prostate cancer risks: an analysis in the VITamins and lifestyle (VITAL) cohort study.
- Author
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Zhou CK, Littman AJ, Levine PH, Hoffman HJ, Cleary SD, White E, and Cook MB
- Subjects
- Adult, Aged, Cohort Studies, Humans, Incidence, Life Style, Male, Middle Aged, Prospective Studies, Risk, Surveys and Questionnaires, Alopecia epidemiology, Prostatic Neoplasms epidemiology
- Abstract
Background: Male pattern baldness and prostate cancer may share common pathophysiological mechanisms in terms of advancing age, heritability, and endogenous hormones. Results from previous epidemiologic studies are inconsistent. Therefore, we investigated the association of prostate cancer risks with male pattern baldness at age 30 years, age 45 years, and baseline (median age = 60.5 years) in the VITamins And Lifestyle (VITAL) cohort study., Methods: We included 32,583 men who were aged 50-76 years and without prior cancer diagnosis (excluding non-melanoma skin cancer) at the start of follow-up. First primary incident prostate cancers were ascertained via linkage to the western Washington Surveillance, Epidemiology, and End Results (SEER) program. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated using Cox proportional hazards regressions with adjustment for potential confounders., Results: During follow-up (median = 9 years), 2,306 incident prostate cancers were diagnosed. Male pattern baldness at age 30 years, age 45 years, and baseline were not statistically significantly associated with overall or subtypes of prostate cancer., Conclusion: This study did not provide support for the hypothesis that male pattern baldness may be a marker for subsequent prostate cancer. Previous evidence indicates that a distinct class of frontal with vertex balding may be associated with increased risk of aggressive prostate cancer, but all such balding classes were captured as a single exposure category by the VITAL cohort questionnaire. Prostate 75:415-423, 2015. © 2014 Wiley Periodicals, Inc., (© 2014 Wiley Periodicals, Inc.)
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- 2015
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39. Relationship between male pattern baldness and the risk of aggressive prostate cancer: an analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
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Zhou CK, Pfeiffer RM, Cleary SD, Hoffman HJ, Levine PH, Chu LW, Hsing AW, and Cook MB
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- Aged, Alopecia physiopathology, Biopsy, Early Detection of Cancer, Follow-Up Studies, Humans, Incidence, Male, Mass Screening, Middle Aged, Neoplasm Grading, Neoplasm Staging, Proportional Hazards Models, Prospective Studies, Prostate pathology, Prostatic Neoplasms physiopathology, Risk Assessment, Risk Factors, United States epidemiology, Alopecia epidemiology, Alopecia pathology, Prostatic Neoplasms epidemiology, Prostatic Neoplasms pathology
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Purpose: Male pattern baldness and prostate cancer appear to share common pathophysiologic mechanisms. However, results from previous studies that assess their relationship have been inconsistent. Therefore, we investigated the association of male pattern baldness at age 45 years with risks of overall and subtypes of prostate cancer in a large, prospective cohort—the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial., Methods: We included 39,070 men from the usual care and screening arms of the trial cohort who had no cancer diagnosis (excluding nonmelanoma skin cancer) at the start of follow-up and recalled their hair-loss patterns at age 45 years. Hazard ratios (HRs) and 95% CIs were estimated by using Cox proportional hazards regression models with age as the time metric., Results: During follow-up (median, 2.78 years), 1,138 incident prostate cancer cases were diagnosed, 571 of which were aggressive (biopsy Gleason score ≥ 7, and/or clinical stage III or greater, and/or fatal). Compared with no baldness, frontal plus moderate vertex baldness at age 45 years was not significantly associated with overall (HR, 1.19; 95% CI, 0.98 to 1.45) or nonaggressive (HR, 0.97; 95% CI, 0.72 to 1.30) prostate cancer risk but was significantly associated with increased risk of aggressive prostate cancer (HR, 1.39; 95% CI, 1.07 to 1.80). Adjustment for covariates did not substantially alter these estimates. Other classes of baldness were not significantly associated with overall or subtypes of prostate cancer., Conclusion: Our analysis indicates that frontal plus moderate vertex baldness at age 45 years is associated with an increased risk of aggressive prostate cancer and supports the possibility of common pathophysiologic mechanisms., (© 2014 by American Society of Clinical Oncology.)
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- 2015
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40. Victor and Erika Webnovela: An Innovative Generation @ Audience Engagement Strategy for Prevention.
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Andrade EL, Evans WD, Edberg MC, Cleary SD, Villalba R, and Batista IC
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- Adolescent, Diffusion of Innovation, Hispanic or Latino statistics & numerical data, Humans, Risk-Taking, Sexual Behavior psychology, Substance-Related Disorders prevention & control, United States, Violence prevention & control, Health Education methods, Hispanic or Latino psychology, Internet, Motion Pictures, Sexual Behavior ethnology, Substance-Related Disorders ethnology, Violence ethnology
- Abstract
Entertainment-education (E-E) approaches for young audiences continue to evolve in order to keep stride with younger generations' affinity for technology. E-E and novelas have been used with a wide variety of audiences in the United States, in particular hard-to-reach Latino populations, and have demonstrated effectiveness in disseminating culturally relevant prevention information for a wide variety of health-related risk factors and behaviors. This study discusses the formative research and active engagement of Latino youth living in Langley Park, Maryland, for the development and filming of an innovative 6-episode webnovela titled Victor and Erika (V&E). V&E is part of a larger branding strategy of the Adelante Positive Youth Development intervention that seeks to prevent substance abuse, sexual risk, and interpersonal violence among Latino youth; V&E is also an intervention component. The V&E webnovela is a dramatic portrayal of the lives of 2 immigrant Latino teenagers that also disseminates risk prevention messages. The storyline represents the turning the corner (to a better life) theme that underlies the Adelante intervention brand. Formative research was conducted for character development (n = 20) and creative development of the episodes (n = 14). Results of the formative research showed that youth recommended inclusion of the following topics in V&E episodes: sex, unintended pregnancy, fidelity, trust, family dynamics, immigration status, violence, school dropout, respect, home life, and poverty. Detailed character and episode descriptions are provided, and the implications of using the V&E series as a tool for in-person and online engagement of youth and the dissemination of prevention messages are also discussed.
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- 2015
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41. Measuring insight through patient self-report: an in-depth analysis of the factor structure of the Birchwood Insight Scale.
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Cleary SD, Bhatty S, Broussard B, Cristofaro SL, Wan CR, and Compton MT
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- Adolescent, Adult, Aged, Factor Analysis, Statistical, Female, Humans, Male, Mental Disorders psychology, Middle Aged, Models, Psychological, Reproducibility of Results, Schizophrenic Psychology, Young Adult, Awareness, Psychological Tests, Psychotic Disorders psychology, Self Report
- Abstract
Little research has focused on item analysis and factor structure of the most commonly used measures of insight. We examined the factorial structure of the Birchwood Insight Scale (BIS), a brief, easy-to-administer, self-report measure. We studied the BIS in 327 first-episode psychosis patients, including a test sample (n=163) and a validation sample (n=164). We then used data from 100 patients with chronic serious mental illnesses as a second, external validation sample. Exploratory factor analysis was conducted with the test subsample, and confirmatory factor analyses with the two validation samples. Confirmatory factor analyses (in both the first-episode psychosis validation sample and the chronic serious mental illness sample) indicated that a single-factor solution, with seven items loading on a single factor-with item 1 ("Some of your symptoms are made by your mind") eliminated-was the best-fitting model. Seven of the eight original BIS items loading on a single factor fit the data well in these samples. Researchers using this efficient measure of patient-reported insight should assess the item distributions and factor structure of the BIS in their samples, and potentially consider eliminating item 1., (Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.)
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- 2014
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42. Measuring trauma and stressful events in childhood and adolescence among patients with first-episode psychosis: initial factor structure, reliability, and validity of the Trauma Experiences Checklist.
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Cristofaro SL, Cleary SD, Ramsay Wan C, Broussard B, Chapman C, Haggard PJ, Jananeh S, Myers NL, and Compton MT
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- Adolescent, Adult, Checklist, Child, Factor Analysis, Statistical, Female, Humans, Male, Parents, Psychiatric Status Rating Scales, Psychometrics instrumentation, Psychometrics statistics & numerical data, Psychotic Disorders psychology, Reproducibility of Results, Risk Factors, Social Environment, Stress Disorders, Post-Traumatic diagnosis, Child Abuse psychology, Life Change Events, Psychotic Disorders diagnosis, Stress Disorders, Post-Traumatic psychology, Surveys and Questionnaires standards
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Past trauma and stressful events, especially in childhood and adolescence, are common among individuals with serious mental illnesses like schizophrenia. Traumatic experiences are thought to be a socio-environmental risk factor not only for poorer outcomes, but also potentially for the onset of these disorders. Because improved measurement tools are needed, we developed and studied, among 205 first-episode psychosis patients, the factor structure, internal consistency reliability, and initial validity of the Trauma Experiences Checklist (TEC), our measure of trauma and stressful events during childhood/adolescence. We assessed validity of subscales using correlations with Childhood Trauma Questionnaire-Short Form, Parental Harsh Discipline, Violence Exposure, and TEC-Informant Version scores. Exploratory factor analysis resulted in two internally consistent subscales (Cronbach's α=0.79 and 0.80, respectively), interpersonal abuse and family stress, and violence, death, and legal involvement. Scores from the former subscale were substantially associated with CTQ-SF physical, emotional, and sexual abuse (r=0.42-0.57, all p<0.001) and Violence Exposure (r=0.49, p<0.001). On the other hand, violence, death, and legal involvement scores were most highly correlated with Violence Exposure (r=0.49, p<0.001), and not with most CTQ-SF subscales. The TEC is a potentially useful tool in assessing diverse traumatic life events across various social contexts during childhood and adolescence., (Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.)
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- 2013
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43. Consistency with the dietary approaches to stop hypertension diet among adults with diabetes.
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Morton S, Saydah S, and Cleary SD
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- Adult, Comorbidity, Cross-Sectional Studies, Diabetes Mellitus diet therapy, Feeding Behavior, Female, Humans, Linear Models, Male, Mental Recall, Nutrition Surveys, United States epidemiology, Diabetes Mellitus epidemiology, Diet, Sodium-Restricted psychology, Diet, Sodium-Restricted standards, Diet, Sodium-Restricted statistics & numerical data, Hypertension diet therapy, Hypertension epidemiology, Nutrition Policy
- Abstract
Few studies have documented whether the dietary patterns of adults with diabetes are similar to the Dietary Approaches to Stop Hypertension (DASH) diet. Our objective was to determine differences in the degree of consistency with the DASH diet among adults with self-reported diabetes (with and without self-reported high blood pressure) compared with those without either disease. It was a cross-sectional study using data from 5,867 nonpregnant, noninstitutionalized adults aged ≥ 20 years with two reliable 24-hour recall dietary interviews in the National Health and Nutrition Examination Survey during 2003-2004 and 2005-2006. Diabetes and hypertension status were obtained from a questionnaire, and degree of consistency with the DASH diet was calculated based on nine nutrient targets (0- to 9-point DASH score). Multiple linear regression (adjusting for age, energy intake, and other covariates such as education, race, and body mass index) was performed to compare mean DASH scores and mean nutrient intakes among adults with diabetes, with and without high blood pressure, to those without either disease. No statistically significant differences were seen in mean DASH score among the three groups in the unadjusted or fully adjusted multivariable models. Compared with adults without either disease, those with only diabetes had higher intakes of fiber (8.1 g/1,000 kcal vs 7.6 g/1,000 kcal; P=0.02) and total fat as a percentage of total energy (35.3% vs 34.1%; P=0.006), and those with both diabetes and hypertension had higher sodium intake (153.0% of DASH target vs 146.6%; P=0.04). This information about individual nutrients could help guide the development of education programs., (Copyright © 2012 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.)
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- 2012
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44. The association between major depressive disorder and obesity in US adolescents: results from the 2001-2004 National Health and Nutrition Examination Survey.
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Merikangas AK, Mendola P, Pastor PN, Reuben CA, and Cleary SD
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- Adolescent, Black or African American, Child, Comorbidity, Female, Hispanic or Latino, Humans, Male, Nutrition Surveys, Odds Ratio, Prevalence, Sex Factors, Young Adult, Depressive Disorder, Major epidemiology, Obesity epidemiology
- Abstract
The association between major depressive disorder (MDD) and obesity was assessed in 4,150 US adolescents aged 12-19 years from the 2001-2004 National Health and Nutrition Examination Survey. Weight and height were measured by health professionals and MDD was based on a structured diagnostic interview. The prevalence of MDD in the past year among US adolescents was 3.2% and 16.8% of US adolescents were obese. After adjustment for sex, age, race/ethnicity and poverty, MDD was not significantly associated with obesity among adolescents overall (adjusted odds ratio (adjOR) = 1.6, 95% confidence interval (CI) = 0.9-2.9), but an increased odds of obesity was observed among males (adjOR = 2.7, 95% CI = 1.1-7.1) and non-Hispanic blacks (adjOR = 3.1, 95% CI = 1.1-8.3) with MDD. Future research on strategies that might reduce the risk of obesity in males and non-Hispanic black adolescents with MDD may be warranted.
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- 2012
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45. Second primary breast, endometrial, and ovarian cancers in Black and White breast cancer survivors over a 35-year time span: effect of age.
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Nsouli-Maktabi HH, Henson DE, Younes N, Young HA, and Cleary SD
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- Adult, Black or African American, Age Factors, Breast Neoplasms ethnology, Endometrial Neoplasms epidemiology, Female, Humans, Middle Aged, Neoplasms, Second Primary ethnology, Ovarian Neoplasms epidemiology, Survivors, United States epidemiology, White People, Breast Neoplasms epidemiology, Neoplasms, Second Primary epidemiology
- Abstract
Breast cancer incidence increases with age and exhibits a Black-to-White crossover around age 45. Breast cancer survivors are at a significantly elevated risk of developing a second primary breast or gynecological cancer compared with the general population. The purpose of this study was to determine whether a similar crossover occurs in hormonally related second primary breast, endometrial, or ovarian cancers in Black and White women. The Surveillance, Epidemiology, and End Results' Registry 9 was used to follow 415,664 White and 39,887 Black female breast cancer survivors, diagnosed at age 19 or older, for a second primary breast, endometrial, or ovarian cancer between 1973 and 2007. Cumulative incidence curves were generated; Pepe and Mori's test was used to test for significance. Second primary breast cancer followed the incidence pattern of the first primary breast cancer in Black and White women diagnosed before age 45. It was opposite of the pattern of first primary breast cancer in Black and White women diagnosed at age 45 or later. Second primary endometrial and ovarian cancers paralleled the incidence pattern of first primaries of the same anatomic site among Black and White women, independent of the age at diagnosis of the first primary breast cancer. Despite the Black-to-White crossover of first primary breast cancer around age 40, the incidence of hormonally related second primaries does not appear affected by the age at diagnosis of the first primary.
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- 2011
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46. Cancers, infections, and endocrine diseases in women with endometriosis.
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Gemmill JA, Stratton P, Cleary SD, Ballweg ML, and Sinaii N
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- Addison Disease epidemiology, Adolescent, Adult, Aged, Comorbidity, Congenital Abnormalities epidemiology, Cross-Sectional Studies, Cushing Syndrome epidemiology, Endometriosis surgery, Female, Humans, Middle Aged, Mitral Valve Prolapse epidemiology, Prevalence, Recurrence, Self Disclosure, Skin Neoplasms epidemiology, Uterine Diseases surgery, Young Adult, Endocrine System Diseases epidemiology, Endometriosis epidemiology, Melanoma epidemiology, Ovarian Neoplasms epidemiology, Respiratory Tract Infections epidemiology, Uterine Diseases epidemiology, Vaginal Diseases epidemiology
- Abstract
Objective: To assess the prevalence of patient-reported, physician-diagnosed comorbid conditions in women with endometriosis., Design: Cross-sectional study of self-reported survey data., Setting: Academic research., Patient(s): Four thousand three hundred thirty-one Endometriosis Association (EA) members reporting surgically diagnosed endometriosis., Intervention(s): None., Main Outcome Measure(s): Self-reported, physician-diagnosed infectious diseases, cancers, and endocrine diseases., Result(s): Nearly two-thirds of women reported one or more of the assessed conditions. Recurrent upper respiratory infections and recurrent vaginal infections were common and more likely in women responding to the EA survey. Melanoma was reported by 0.7% (n=29), breast cancer by 0.4% (n=16), and ovarian cancer by 0.2% (n=10). While ovarian cancer and melanoma were significantly more common than in the general population, breast cancer was surprisingly less common. Addison's disease and Cushing's syndrome were rare (0.2% and 0.1%, respectively)., Conclusion(s): Respondents reported a higher prevalence of recurrent upper respiratory or vaginal infections, melanoma, and ovarian cancer than the general population. These findings document other potential associations related to the immune system, which may help focus future research into this disease., (Published by Elsevier Inc.)
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- 2010
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47. SAFER Latinos: a community partnership to address contributing factors for Latino youth violence.
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Edberg M, Cleary SD, Andrade E, Leiva R, Bazurto M, Rivera MI, Montero L, and Calderon M
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- Adolescent, Health Promotion, Health Status Disparities, Humans, Maryland, Models, Theoretical, Risk Factors, Social Class, Community Networks, Hispanic or Latino, Violence ethnology, Violence prevention & control
- Abstract
Background: This paper describes a multilevel youth violence prevention effort called SAFER Latinos (Seguridad, Apoyo, Familia, Educacion, y Recursos), a collaboration between The George Washington University School of Public Health and Health Services (GWU) and two key Latino community organizations., Objectives: To implement and evaluate an intervention addressing factors within the social ecology of an immigrant Latino community., Methods: The intervention includes (1) Social promotores for family outreach and problem resolution; (2) Youth peer advocates at the high school level; (3) a drop-in center with support services for families and youth; and (4) community events, capacity building, and messages. Evaluation includes a baseline and follow-up surveys (N = 1,400) and focus groups., Lessons Learned: (1) Community circumstances change, requiring regular program adaptation. (2) Community interventions with research face potential contradictions in purpose impacting management of the collaboration and model fidelity. (3) Etiological models tied to interventions may have to be revisited owing to changes in the character and dynamics of the immigrant community.
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- 2010
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48. The SAFER Latinos project: Addressing a community ecology underlying Latino youth violence.
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Edberg M, Cleary SD, Collins E, Klevens J, Leiva R, Bazurto M, Rivera I, del Cid AT, Montero L, and Calderon M
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- Adolescent, Age Factors, Central America ethnology, Emigrants and Immigrants, Female, Health Education methods, Humans, Male, Models, Psychological, Program Evaluation, Social Participation, United States, Violence statistics & numerical data, Young Adult, Health Education organization & administration, Hispanic or Latino statistics & numerical data, Preventive Health Services, Program Development, Residence Characteristics, Violence prevention & control
- Abstract
This paper describes the intervention model, early implementation experience, and challenges for the Seguridad, Apoyo, Familia, Educacion, y Recursos (SAFER) Latinos project. The SAFER Latinos project is an attempt to build the evidence for a multilevel participatory youth violence prevention model tailored to the specific circumstances of Central American immigrants. Specific circumstances targeted in this intervention are decreased family cohesion as a result of sequential immigration (i.e., parents arriving first and bringing their children years later or youth arriving without parents); multiple school barriers; community disorganization and low community efficacy; limited access to services; and a social context (including gang presence) that is linked to youth norms supporting violence. In its implementation, the initial intervention model was adapted to address barriers and challenges. These are described, along with lessons learned and the ongoing evaluation.
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- 2010
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49. Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis.
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Greene R, Stratton P, Cleary SD, Ballweg ML, and Sinaii N
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- Adolescent, Adult, Cross-Sectional Studies, Endometriosis complications, Endometriosis epidemiology, Female, Health Surveys, Humans, Incidence, Infertility, Female epidemiology, Infertility, Female etiology, Middle Aged, Pain, Postoperative epidemiology, Pelvic Pain epidemiology, Pelvic Pain etiology, Racial Groups, Surveys and Questionnaires, Endometriosis diagnosis, Endometriosis surgery, Gynecologic Surgical Procedures adverse effects
- Abstract
Objective: To determine whether first physician seen and symptoms beginning in adolescence have an impact on the diagnostic experience of endometriosis., Design: Cross-sectional study of self-reported survey data., Setting: Academic research., Patient(s): Four thousand three hundred thirty-four Endometriosis Association Survey respondents reporting surgical diagnosis of endometriosis., Intervention(s): None., Main Outcome Measure(s): Specialty of first physician seen, timing of onset of symptoms, time to seeking medical care and to diagnosis, number of physicians seen, and satisfaction with care., Result(s): Almost all respondents reported pelvic pain. Fifty percent first saw a gynecologist and 45% saw a generalist for symptoms related to endometriosis. Two thirds reported symptoms beginning during adolescence; they waited longer to seek medical care than adults did. Those seeing a generalist first took longest to get diagnosed; those seeing a gynecologist first saw fewer physicians. Sometime before diagnosis, 63% were told nothing was wrong with them., Conclusion(s): Women and girls who reported seeing a gynecologist first for symptoms related to endometriosis were more likely to have a shorter time to diagnosis, to see fewer physicians, and to report a better experience overall with their physicians. The majority reported symptoms beginning during adolescence, also reporting a longer time and worse experience while obtaining a diagnosis.
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- 2009
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50. Treatment utilization for endometriosis symptoms: a cross-sectional survey study of lifetime experience.
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Sinaii N, Cleary SD, Younes N, Ballweg ML, and Stratton P
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- Adolescent, Adult, Analgesics therapeutic use, Cross-Sectional Studies, Demography, Endometriosis physiopathology, Endometriosis surgery, Female, Humans, Middle Aged, National Institutes of Health (U.S.), Pelvic Pain etiology, Socioeconomic Factors, Surveys and Questionnaires, Treatment Outcome, United States, Complementary Therapies, Endometriosis therapy
- Abstract
Objective: To examine the lifetime utilization and perceived benefit of medical treatments and surgical procedures for endometriosis-related symptoms., Design: Cross-sectional study of self-reported survey data., Setting: Academic research setting., Patient(s): Self-reported surgically diagnosed endometriosis by 1,160 women responding to the 1998 Endometriosis Association survey., Intervention(s): None., Main Outcome Measure(s): Use, perceived helpfulness, and outcomes of medical treatments and surgical procedures., Result(s): Ninety-five percent of respondents reported pelvic pain, had endured symptoms on average of 16 years, and were young (mean: 36 years), white, and educated. Many women (46%) had tried three or more medical treatments, and almost 20% took them for 10+ years. Many reported medical treatments as helpful for symptoms (range, 36.4%-61.9%), but some reported stopping because of ineffectiveness (range, 15.6%-26.1%) or side effects (range, 10.0%-43.5%). Danazol or medroxyprogesterone acetate (MPA) was most commonly stopped because of side effects (range, 40.7%-43.5%). Surgical procedures were performed at least three times on 42%. Nearly 20% had a hysterectomy or oophorectomy; these procedures were reported as most successful in improving symptoms (45.9% and 37.8%, respectively)., Conclusion(s): Despite reporting various treatments as helpful, women used many different types and endured symptoms for an average of almost two decades, indicating the profound effect of endometriosis on women's health.
- Published
- 2007
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