1. Psychometric Properties of a Modified KINDL-R Questionnaire for Adolescents and Adults, and Construction of a Brief Version, the KINDL-A(dult)B(rief) Questionnaire, KINDL-AB
- Author
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Neuner, Bruno, Krampe, Henning, McCarthy, William J, Reinke, Sarah, Kowalski, Dorothee, Clausnizer, Hartmut, Shneyder, Maria, Rocke, Angela, and Nowak-Göttl, Ulrike
- Subjects
Biomedical and Clinical Sciences ,Cardiovascular Medicine and Haematology ,Adolescent ,Adult ,Aged ,Blood Coagulation Disorders ,Cross-Sectional Studies ,Female ,Humans ,Male ,Middle Aged ,Psychometrics ,Quality of Life ,Reproducibility of Results ,Surveys and Questionnaires ,Quality of life ,Hereditary bleeding disorder ,Transition ,KINDL-R questionnaire ,Cardiorespiratory Medicine and Haematology ,Immunology ,Cardiovascular medicine and haematology - Abstract
Background/aimsThe generic quality of life KINDL-R -questionnaire is validated for use in children/adolescents ≤16 years. The aim of this cross-sectional investigation was to modify the KINDL-R questionnaire for use in adults and to validate its psychometric properties.MethodsFive items of the KINDL-R questionnaire were adapted and the newly developed KINDL-A(dult) questionnaire administered to 255 patients with hereditary and acquired bleeding disorders (mean age 53 years). Its internal consistency and convergent and divergent construct validity were investigated and confirmatory factor analysis was used to evaluate the latent factor structure.ResultsThe KINDL-A questionnaire showed satisfactory reliability, varying construct validity, but inconclusive factor structure. The KINDL-AB(rief) was developed by removing half of the items and combining 2 sub-axes. This led to factor loadings between 0.62 and 0.91 and increased overall fit (Goodness of fit > 0.8 and Root Mean Square Error of Approximation, RMSEA, < 0.08). Results were validated in 966 healthy blood donors (mean age 38 years). In this group, the KINDL-AB questionnaire showed factor loadings between 0.43 and 0.77, Goodness of fit > 0.95 and RMSEA < 0.05.ConclusionsThe new KINDL-AB suggests sufficient to good psychometric properties in adult patients with hereditary and acquired bleeding disorders.
- Published
- 2018