Search

Your search keyword '"Claudia R. Gordijo"' showing total 169 results
Start Over Author "Claudia R. Gordijo"
169 results on '"Claudia R. Gordijo"'

1. Data from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia

Author

Xiao Yu Wu, Ralph S. DaCosta, Andrew M. Rauth, Azusa Maeda, Mohammad Ali Amini, Claudia R. Gordijo, and Azhar Z. Abbasi

Abstract

Hypoxia in the tumor microenvironment (TME) mediates resistance to radiotherapy and contributes to poor prognosis in patients receiving radiotherapy. Here we report the design of clinically suitable formulations of hybrid manganese dioxide (MnO2) nanoparticles (MDNP) using biocompatible materials to reoxygenate the TME by reacting with endogenous H2O2. MDNP containing hydrophilic terpolymer-protein-MnO2 or hydrophobic polymer-lipid-MnO2 provided different oxygen generation rates in the TME relevant to different clinical settings. In highly hypoxic murine or human xenograft breast tumor models, we found that administering either MDNP formulation before radiotherapy modulated tumor hypoxia and increased radiotherapy efficacy, acting to reduce tumor growth, VEGF expression, and vascular density. MDNP treatment also increased apoptosis and DNA double strand breaks, increasing median host survival 3- to 5-fold. Notably, in the murine model, approximately 40% of tumor-bearing mice were tumor-free after a single treatment with MDNPs plus radiotherapy at a 2.5-fold lower dose than required to achieve the same curative treatment without MDNPs. Overall, our findings offer a preclinical proof of concept for the use of MDNP formulations as effective radiotherapy adjuvants. Cancer Res; 76(22); 6643–56. ©2016 AACR.

Published
2023

3. Supplementary Figures S1-S9 from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia

Author

Xiao Yu Wu, Ralph S. DaCosta, Andrew M. Rauth, Azusa Maeda, Mohammad Ali Amini, Claudia R. Gordijo, and Azhar Z. Abbasi

Abstract

Characterization of NPs (S1); Immunofluorescence detection and quantification of EMT6 tumor hypoxia (S2); IF detection and quantification of EMT6 tumor hypoxia (S3); Quantification of IHC images (S4); Effect of IT treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S5); Effect of IT administered MDNPs alone or in combination with RT on the growth of murine EMT6 breast tumor (S6); Effect of IV treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S7); H&E stained mammary fat pad tissues of a healthy mouse and a LMD+RT surviving mouse (S8); Effect of MDNPs treatment post irradiation (S9).

Published
2023

7. CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Author

Benjamin G. Perry, Rommie E. Amaro, Claudia R. Gordijo, Cora Scholten, Andrew R. Leach, Alexander Hillisch, Kristina Edfeldt, Johanna M. Jansen, Uta Lessel, Gerhard F. Ecker, Rima Al-awar, Matthieu Schapira, Daniel Kuhn, Masoud Vedadi, John D. Chodera, Suzanne Ackloo, Ian Dunham, Robert A. Batey, Wendy D. Cornell, Ingo Muegge, Ulrich A. K. Betz, Hatylas Azevedo, Cristian Bologa, Yoshua Bengio, Kumar Singh Saikatendu, Timothy M. Willson, Aled M. Edwards, Vijayaratnam Santhakumar, John Moult, Alpha A. Lee, Patrick Riley, Michael K. Gilson, Matthew H. Todd, Gerhard Hessler, Cheryl H. Arrowsmith, Andrea Volkamer, Tudor I. Oprea, Anders Hogner, and John J. Irwin

Subjects
Public–private partnership, Open science, Development (topology), Computer science, Drug discovery, Critical assessment, Relevance (information retrieval), Benchmarking, Cache, Data science
Abstract

Computational approaches in drug discovery and development hold great promise, with artificial intelligence methods undergoing widespread contemporary use, but the experimental validation of these new approaches is frequently inadequate. We are initiating Critical Assessment of Computational Hit-finding Experiments (CACHE) as a public benchmarking project that aims to accelerate the development of small molecule hit-finding algorithms by competitive assessment. Compounds will be identified by participants using a wide range of computational methods for dozens of protein targets selected for different types of prediction scenarios, as well as for their potential biological or pharmaceutical relevance. Community-generated predictions will be tested centrally and rigorously in an experimental hub(s), and all data, including the chemical structures of experimentally tested compounds, will be made publicly available without restrictions. The ability of a range of computational approaches to find novel compounds will be evaluated, compared, and published. The overarching goal of CACHE is to accelerate the development of computational chemistry methods by providing rapid and unbiased feedback to those developing methods, with an ancillary and valuable benefit of identifying new compound-protein binding pairs for biologically interesting targets. The initiative builds on the power of crowd sourcing and expands the open science paradigm for drug discovery.

Published
2021

8. CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Author

Suzanne Ackloo, Rima Al-awar, Rommie E. Amaro, Cheryl H. Arrowsmith, Hatylas Azevedo, Robert A. Batey, Yoshua Bengio, Ulrich A.K. Betz, Cristian G. Bologa, John D. Chodera, Wendy D. Cornell, Ian Dunham, Gerhard F. Ecker, Kristina Edfeldt, Aled M. Edwards, Michael K. Gilson, Claudia R. Gordijo, Gerhard Hessler, Alexander Hillisch, Anders Hogner, John J. Irwin, Johanna M. Jansen, Daniel Kuhn, Andrew R. Leach, Alpha A. Lee, Uta Lessel, John Moult, Ingo Muegge, Tudor I. Oprea, Benjamin G. Perry, Patrick Riley, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Matthieu Schapira, Cora Scholten, Matthew H. Todd, Masoud Vedadi, Andrea Volkamer, and Timothy M. Willson

Subjects
public-private partnership, machine learning, in silico design, CACHE, open science, small molecule drug discovery, artificial intelligence, computational chemistry, hit-finding challenges
Abstract

Computational approaches in drug discovery and development hold great promise, with artificial intelligence methods undergoing widespread contemporary use, but the experimental validation of these new approaches is frequently inadequate. We are initiating Critical Assessment of Computational Hit-finding Experiments (CACHE) as a public benchmarking project that aims to accelerate the development of small molecule hit-finding algorithms by competitive assessment. Compounds will be identified by participants using a wide range of computational methods for dozens of protein targets selected for different types of prediction scenarios, as well as for their potential biological or pharmaceutical relevance. Community-generated predictions will be tested centrally and rigorously in an experimental hub(s), and all data, including the chemical structures of experimentally tested compounds, will be made publicly available without restrictions. The ability of a range of computational approaches to find novel compounds will be evaluated, compared, and published. The overarching goal of CACHE is to accelerate the development of computational chemistry methods by providing rapid and unbiased feedback to those developing methods, with an ancillary and valuable benefit of identifying new compound-protein binding pairs for biologically interesting targets. The initiative builds on the power of crowd sourcing and expands the open science paradigm for drug discovery., ACKNOWLEDGEMENTS The Structural Genomics Consortium is a registered charity (no: 1097737) that receives funds from Bayer AG, Boehringer Ingelheim, Bristol Myers Squibb, Genentech, Genome Canada through Ontario Genomics Institute [OGI-196], Janssen, Merck KGaA (aka EMD in Canada and US), Pfizer, Takeda and the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875510. The JU receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA and Ontario Institute for Cancer Research, Royal Institution for the Advancement of Learning McGill University, Kungliga Tekniska Hoegskolan, Diamond Light Source Limited. This communication reflects the views of the authors and the JU is not liable for any use that may be made of the information contained herein. M. K. Gilson acknowledges funding from National Institute of General Medical Sciences (GM061300). J. J. Irwin acknowledges funding from National Institute of General Medical Sciences (GM133836). These findings are solely of the authors and do not necessarily represent the views of the NIH. The Lee laboratory at the University of Cambridge receives funding from multiple sources, including Pfizer, AstraZeneca, the Engineering and Physical Sciences Research Council and the Winton Programme for the Physics of Sustainability. T.I. Oprea and C. G. Bologa acknowledge funding from the National Institutes of Health Common Fund program, Illuminating the Druggable Genome (CA224370 and TR002278). COMPETING INTERESTS M. K. Gilson has an equity interest in and is a cofounder and scientific advisor of VeraChem LLC. J. J. Irwin is a co-founder of Blue Dolphin LLC, which undertakes fee-for-service ligand discovery. A.A. Lee is the chief scientific officer and a shareholder of PostEra Inc. T. I. Oprea has received honoraria from or consulted for Abbott, AstraZeneca, Chiron, Genentech, Infinity Pharmaceuticals, Merz Pharmaceuticals, Merck Darmstadt, Mitsubishi Tanabe, Novartis, Ono Pharmaceuticals, Pfizer, Roche, Sanofi and Wyeth, and is on the Scientific Advisory Board of ChemDiv and InSilico Medicine.

Published
2021

9. Combining Tumor Microenvironment Modulating Nanoparticles with Doxorubicin to Enhance Chemotherapeutic Efficacy and Boost Antitumor Immunity

Author

Mohammad Ali Amini, Claudia R. Gordijo, Li Zhang, Hoyin Lip, Jason Li, Xiao Yu Wu, Andrew M. Rauth, Azhar Z. Abbasi, Branson Chen, and Ping Cai

Subjects
Cancer Research, Combination therapy, Polymers, medicine.medical_treatment, Apoptosis, Breast Neoplasms, Mice, 03 medical and health sciences, 0302 clinical medicine, Tumor Cells, Cultured, Tumor Microenvironment, medicine, Splenocyte, Animals, Humans, Doxorubicin, Cell Proliferation, Mice, Inbred BALB C, Chemotherapy, Tumor microenvironment, Antibiotics, Antineoplastic, business.industry, technology, industry, and agriculture, Oxides, Immunosuppression, Immunotherapy, Xenograft Model Antitumor Assays, 3. Good health, Manganese Compounds, Oncology, 030220 oncology & carcinogenesis, Cancer research, Nanoparticles, Drug Therapy, Combination, Female, business, medicine.drug
Abstract

Background Tumor microenvironment (TME) and associated multiple factors are found to contribute to the failures in cancer therapies, including chemo- and immunotherapy. Here we report a new multimodal strategy that uses a bioreactive multifunctional hybrid polymer-lipid encapsulated manganese dioxide nanoparticle (PLMD NP) system to remodel the TME, suppress drug resistance factors, reverse immunosuppressive conditions, and enhance chemotherapy efficacy. Methods The influence of PLMD NPs on enhancing cellular uptake in EMT6 mouse breast cancer cells and tumor penetration of doxorubicin (DOX) in EMT6 orthotopic breast tumor mouse model was evaluated using confocal microscopy (n = 3-4). Immunohistochemistry was employed to examine the effect of PLMD NPs on downregulating hypoxia-induced drug resistance proteins and anticancer activity of DOX (n = 3-4). The efficacy of the combination therapy with PLMD NPS and DOX was assessed in murine EMT6 (n = 15-23) and 4T1 (n = 7) orthotopic breast tumor mouse models. Rechallenge and splenocyte transfer were performed to validate the stimulation of adaptive tumor immunity in the surviving mice. Results PLMD NPs enhanced intratumoral penetration and efficacy of DOX, and reduced intratumoral expression of P-glycoprotein, p53, and carbonic anhydrase IX by 74.5%, 38.0%, and 58.8% vs saline control, respectively. Combination treatment with PLMD NPs and DOX increased the number of tumor-infiltrated CD8+ T cells and resulted in up to 60.0% complete tumor regression. Of naive mice (n = 7) that received splenocytes from the PLMD+DOX-treated surviving mice, 57.1% completely suppressed tumor growth whereas 100% of mice that received splenocytes from DOX-treated mice (n = 3) and the control group (n = 7) showed rapid tumor growth. Conclusions The clinically suitable PLMD NPs can effectively downregulate TME-associated drug resistance and immunosuppression. The combination therapy with PLMD NPs and DOX is a multimodal and translational treatment approach for enhancing chemotherapeutic efficacy and boosting antitumor immunity.

Published
2018

10. Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model

Author

Xiao Yu Wu, Kuan Chen, Jason Li, Claudia R. Gordijo, Azhar Z. Abbasi, Oliver Plettenburg, Michael K.L. Chu, Matthias Löhn, Adria Giacca, and Hibret A. Adissu

Subjects
Blood Glucose, Male, Materials science, Biocompatibility, Polymers, Diabetic rat, medicine.medical_treatment, Biophysics, Biocompatible Materials, Bioengineering, Streptozocin, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, Biomaterials, chemistry.chemical_compound, Drug Delivery Systems, Insulin Infusion Systems, Immune system, medicine, Animals, Insulin, Inflammation, Microporous material, Catalase, Fibrosis, Rats, Disease Models, Animal, Glucose, Membrane, chemistry, Mechanics of Materials, Drug Design, Ceramics and Composites, Microtechnology, Implant, Ethylene glycol, Biomedical engineering
Abstract

Implantation of a medical implant within the body inevitably triggers a host inflammatory response that negatively impacts its function and longevity. Nevertheless, the degree and severity of this response may be reduced by selecting appropriate materials, implant geometry, surface topography and surface treatment. Here we demonstrate a strategy to improve the biocompatibility of a chemically-driven closed-loop insulin delivery implant. A microfabricated microporous, poly(ethylene glycol)-grafted polydimethylsiloxane membrane was placed on top of the glucose-responsive insulin release plug of the implant. Implant biocompatibility was assessed in healthy rats while implant function was evaluated in a type 1 diabetic rat model. The microporous membrane with a small distance to the plug provided a geometric barrier to inflammatory cell migration and prevented leukocyte-mediated degradation of the plug for at least 30 days. Membrane-protected devices elicited a significantly milder inflammatory response and formation of a well-defined fibrous capsule at the device opening compared to unprotected devices. The device's glucose-responsiveness was nearly unchanged, although the insulin release rate decreased with decreasing pore size. The microporous membrane improved biocompatibility and prolonged in vivo efficacy of the implant by ∼3-fold. This work suggests the importance of implant design in modulating inflammatory response and thereby extending the functional duration of the implant.

Published
2015

11. Design of Hybrid MnO2-Polymer-Lipid Nanoparticles with Tunable Oxygen Generation Rates and Tumor Accumulation for Cancer Treatment

Author

Peter J. O'Brien, Ping Cai, Xiao Yu Wu, Ho Yin Lip, Mohammad Ali Amini, Azusa Maeda, Claudia R. Gordijo, Andrew M. Rauth, Ralph S. DaCosta, and Azhar Z. Abbasi

Subjects
Tumor microenvironment, Materials science, Tumor hypoxia, Biocompatibility, Nanotechnology, Hypoxia (medical), Tumor Oxygenation, Condensed Matter Physics, In vitro, Electronic, Optical and Magnetic Materials, Biomaterials, In vivo, Electrochemistry, medicine, Systemic administration, Biophysics, medicine.symptom
Abstract

Manganese dioxide (MnO2) nanoparticles (NPs) were discovered in previous work to be effective in improving tumor oxygenation (hypoxia) and reducing H2O2 and acidity in the tumor microenvironment (TME) via local injection. To develop MnO2 formulations useful for clinical application, hybrid NPs are designed with tailored hydrophobicity and structure suitable for intravenous injection, with good blood circulation, biocompatibility, high tumor accumulation, and programmable oxygen generation rate. Two different hybrid NPs are constructed by embedding polyelectrolyte-MnO2 (PMD) in hydrophilic terpolymer/protein-MnO2 (TMD) or hydrophobic polymer/lipid-MnO2 (LMD) matrices. The in vitro reactivity of the MnO2 toward H2O2 is controlled by matrix material and NP structure and dependent on pH with up to two-fold higher O2 generation rate at acidic (tumor) pH than at systemic pH. The hybrid NPs are found to be safe to cells in vitro and organs in vivo and effectively decrease tumor hypoxia and hypoxia-inducible-factor-1alpha through local or systemic administration. Fast acting TMD reduces tumor hypoxia by 70% in 0.5 h by local injection. Slow acting LMD exhibits superior tumor accumulation and retention through the systemic administration and decreased hypoxia by 45%. These findings encourage a broader use of hybrid MD NPs to overcome TME factors for cancer treatment.

Published
2015

12. Enhancing thermal stability of a highly concentrated insulin formulation with Pluronic F-127 for long-term use in microfabricated implantable devices

Author

Jason Li, Xiao Yu Wu, Adria Giacca, Brian Lu, Oliver Plettenburg, Claudia R. Gordijo, Kuan Chen, Sako Mirzaie, and Michael K. Chu

Subjects
Blood Glucose, Male, Circular dichroism, medicine.medical_treatment, Pharmaceutical Science, Nanotechnology, 02 engineering and technology, Poloxamer, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Diabetes Mellitus, Experimental, Hydrophobic effect, Rats, Sprague-Dawley, Drug Stability, Amphiphile, medicine, Animals, Hypoglycemic Agents, Insulin, Thermal stability, chemistry.chemical_classification, Drug Implants, Temperature, Polymer, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Drug Liberation, chemistry, Delayed-Action Preparations, Drug delivery, Biophysics, Microtechnology, 0210 nano-technology, Gels
Abstract

Development of highly concentrated formulations of protein and peptide drugs is a major challenge due to increased susceptibility to aggregation and precipitation. Numerous drug delivery systems including implantable and wearable controlled-release devices require thermally stable formulations with high concentrations due to limited device sizes and long-term use. Herein we report a highly concentrated insulin gel formulation (up to 80 mg/mL, corresponding to 2200 IU/mL), stabilized with a non-ionic amphiphilic triblock copolymer (i.e., Pluronic F-127 (PF-127)). Chemical and physical stability of insulin was found to be improved with increasing polymer concentration, as evidenced by reduced insulin fibrillation, formation of degradation products, and preserved secondary structure as measured by HPLC and circular dichroism spectroscopy, respectively. This formulation exhibits excellent insulin stability for up to 30 days in vitro under conditions of continuous shear at 37 °C, attributable to the amphiphilic properties of the copolymer and increased formulation viscosity. The mechanism of stabilizing insulin structure by PF-127 was investigated by coarse-grained molecular dynamics (CG-MD), all-atom MD, and molecular docking simulations. The computation results revealed that PF-127 could reduce fibrillation of insulin by stabilizing the secondary structure of unfolded insulin and forming hydrophobic interaction with native insulin. The gel formulations contained in microfabricated membrane-reservoir devices released insulin at a constant rate dependent on both membrane porosity and copolymer concentration. Subcutaneous implantation of the gel formulation-containing devices into diabetic rats resulted in normal blood glucose levels for the duration of drug release. These findings suggest that the thermally stable gel formulations are suitable for long-term and implantable drug delivery applications.

Published
2017

13. Multifunctional Albumin–MnO2 Nanoparticles Modulate Solid Tumor Microenvironment by Attenuating Hypoxia, Acidosis, Vascular Endothelial Growth Factor and Enhance Radiation Response

Author

Ralph S. DaCosta, Angela Ip, Claudia R. Gordijo, Azhar Z. Abbasi, Preethy Prasad, Xiao Yu Wu, Andrew M. Rauth, and Azusa Maeda

Subjects
chemistry.chemical_classification, Reactive oxygen species, Tumor microenvironment, biology, General Engineering, Serum albumin, General Physics and Astronomy, In vitro, 3. Good health, Vascular endothelial growth factor, chemistry.chemical_compound, chemistry, Biochemistry, Tumor progression, Cancer cell, biology.protein, medicine, Cancer research, General Materials Science, medicine.symptom, Acidosis
Abstract

Insufficient oxygenation (hypoxia), acidic pH (acidosis), and elevated levels of reactive oxygen species (ROS), such as H2O2, are characteristic abnormalities of the tumor microenvironment (TME). These abnormalities promote tumor aggressiveness, metastasis, and resistance to therapies. To date, there is no treatment available for comprehensive modulation of the TME. Approaches so far have been limited to regulating hypoxia, acidosis, or ROS individually, without accounting for their interdependent effects on tumor progression and response to treatments. Hence we have engineered multifunctional and colloidally stable bioinorganic nanoparticles composed of polyelectrolyte–albumin complex and MnO2 nanoparticles (A-MnO2 NPs) and utilized the reactivity of MnO2 toward peroxides for regulation of the TME with simultaneous oxygen generation and pH increase. In vitro studies showed that these NPs can generate oxygen by reacting with H2O2 produced by cancer cells under hypoxic conditions. A-MnO2 NPs simultaneously...

Published
2014

15. Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia

Author

Azhar Z. Abbasi, Mohammad Ali Amini, Claudia R. Gordijo, Ralph S. DaCosta, Azusa Maeda, Andrew M. Rauth, and Xiao Yu Wu

Subjects
Cancer Research, Pathology, medicine.medical_specialty, medicine.medical_treatment, Endogeny, Breast Neoplasms, 02 engineering and technology, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Humans, Tumor microenvironment, Tumor hypoxia, Radiotherapy, Cancer, Oxides, Hypoxia (medical), 021001 nanoscience & nanotechnology, medicine.disease, Radiation therapy, Oncology, Manganese Compounds, Cell culture, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, Nanoparticles, Tumor Hypoxia, Female, medicine.symptom, 0210 nano-technology
Abstract

Hypoxia in the tumor microenvironment (TME) mediates resistance to radiotherapy and contributes to poor prognosis in patients receiving radiotherapy. Here we report the design of clinically suitable formulations of hybrid manganese dioxide (MnO2) nanoparticles (MDNP) using biocompatible materials to reoxygenate the TME by reacting with endogenous H2O2. MDNP containing hydrophilic terpolymer-protein-MnO2 or hydrophobic polymer-lipid-MnO2 provided different oxygen generation rates in the TME relevant to different clinical settings. In highly hypoxic murine or human xenograft breast tumor models, we found that administering either MDNP formulation before radiotherapy modulated tumor hypoxia and increased radiotherapy efficacy, acting to reduce tumor growth, VEGF expression, and vascular density. MDNP treatment also increased apoptosis and DNA double strand breaks, increasing median host survival 3- to 5-fold. Notably, in the murine model, approximately 40% of tumor-bearing mice were tumor-free after a single treatment with MDNPs plus radiotherapy at a 2.5-fold lower dose than required to achieve the same curative treatment without MDNPs. Overall, our findings offer a preclinical proof of concept for the use of MDNP formulations as effective radiotherapy adjuvants. Cancer Res; 76(22); 6643–56. ©2016 AACR.

Published
2015

16. Nanotechnology-Enabled Closed Loop Insulin Delivery Device: In Vitro and In Vivo Evaluation of Glucose-Regulated Insulin Release for Diabetes Control

Author

Adria Giacca, Leonardo D. Bonifacio, Adam J. Shuhendler, Huiyu Huang, Xiao Yu Wu, Geoffrey A. Ozin, Simon Chiang, Khajag Koulajian, and Claudia R. Gordijo

Subjects
chemistry.chemical_classification, Materials science, biology, Biocompatibility, Insulin, medicine.medical_treatment, Pharmacology, Condensed Matter Physics, In vitro, Electronic, Optical and Magnetic Materials, Biomaterials, Enzyme, chemistry, In vivo, Electrochemistry, PEGylation, medicine, biology.protein, Glucose oxidase, Bovine serum albumin
Abstract

Recently, a new multifunctional, bio-inorganic nanocomposite membrane with the ability to self-regulate the release of insulin in response to blood glucose (BG) levels was reported. Herein, the application of this material as part of a small, implantable, closed-loop insulin delivery device designed to continuously monitor BG concentrations and regulate insulin release is proposed. The insulin delivery device consists of a nanocomposite glucose-responsive plug covalently bound to an insulin reservoir made of surface-modified silicone. The plug is prepared with crosslinked bovine serum albumin (BSA) and enzymes (glucose oxidase (GOx) and catalase (CAT)), pH-responsive hydrogel nanoparticles, and multifunctional MnO2 nanoparticles. The plug functions both as a glucose sensor and controlled delivery unit to release higher rates of insulin from the reservoir in response to hyperglycemic BG levels and basal insulin rates at normal BG concentration. The surfaces of the device are modified by silanization followed by PEGylation to ensure its safety and biocompatibility and the stability of encased insulin. Our results show that insulin release can be modulated in vitro in response to glucose concentrations. In vivo experiments show that the glycemia of diabetic rats can be controlled with implantation of the prototype device. The glucose-responsiveness of the device is also demonstrated by rapid drop in BG level after challenging diabetic rats with bolus injection of glucose solution. In addition, it is demonstrated that surface PEGylation of the device is necessary for reducing the immune response of the host to the implanted foreign object and maintaining insulin stability and bioactivity. With this molecular architecture and the bio-inorganic nanocomposite plug, the device has the ability to maintain normal BG levels in diabetic rats.

Published
2010

17. Abstract 5218: Boosting doxorubicin-induced immunogenic cell death by using tumor microenvironment modulating nanoparticles

Author

Li Zhang, Claudia R. Gordijo, Azhar Z. Abbasi, Hoyin Lip, Xiao Yu Wu, Jason Li, Michael Rauth, Mohammad Ali Amini, and Ping Cai

Subjects
Cancer Research, Tumor microenvironment, Tumor hypoxia, business.industry, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Tumor antigen, 0104 chemical sciences, Immune system, Oncology, Cancer cell, medicine, Splenocyte, Cancer research, Immunogenic cell death, Doxorubicin, 0210 nano-technology, business, medicine.drug
Abstract

Background: Immunogenic cell death (ICD) is a cell death modality which triggers an immune response against dead-cell antigens, particularly when they derive from cancer cells. ICD has been reported to be highly induced by anthracycline drugs, such as doxorubicin (DOX), via facilitating tumor antigen presentation to and activation of T cells. However, these immunogenic effects may be compromised due to the immunosuppressive tumor microenvironment (TME), such as excess ROS, particularly H2O2, produced by tumor cells and dysfunctional macrophages in the tumor. We hypothesize that modulating immunosuppressive factors in the TME can enhance tumor response to chemotherapy and boost immunity. Specifically, polymer-lipid encapsulated manganese dioxide nanoparticles (PLMD NPs) are used to reduce tumor hypoxia and ROS by scavenging H2O2 and generating oxygen. Antitumor immunity against the cancer cells can be enhanced by the combination therapy with PLMD and DOX. Methods: PLMD NPs were prepared by dispersing MnO2 precursor particles in melted lipid and polymer in a surfactant-containing aqueous medium. The efficacy of the combination treatment was evaluated in immunocompetent mice-bearing orthotopic murine EMT6 breast tumor. The mice were treated by intravenous (IV) injection of free DOX alone, or 4 h after PLMD NP IV injection. A re-challenge study was performed by re-inoculating EMT6 cells in cured mice 120 days after the initial treatments. to validate the presence of adaptive anti-tumor immunity in the animals treated with PLMD+DOX combination, splenocyte transfer study was carried out. Ex-vivo imaging techniques were used to measure the number of infiltrated CD8+ T cells into the tumor and polarization of the M2 to M1 macrophages. Results: The PLMD+DOX combination treatment resulted in the median survival time by ~ 5.6-fold as compared to DOX alone, and led to 60% cure rate (9 out of 15 mice). This combination therapy also generated anti-tumor immunity against tumor re-inoculation in 88% of surviving mice and provided anti-tumor immunity in naïve mice that received splenocyte transfer with 57% of mice without tumor growth after inoculation. Ex-vivo studies resulted a 400% increase in the number of intratumoral CD8+ T cells, 5 days after PLMD+DOX treatment, while DOX alone treatment showed only 150% increase when compared to saline treatment. Moreover, M1 macrophages-related CD86 positive cells were found up-regulated by 51% while a significant loss of M2 marker CD163 (-47%) was observed in PLMD+DOX-treated tumors compared to DOX alone-treated ones. Conclusions: The present work demonstrated that clinically suitable PLMD NPs can effectively downregulate TME-associated immunosuppression factors and boost DOX efficacy. The PLMD NPs and DOX combination therapy presents a multimodal and a translational treatment approach to enhancing DOX-induced ICD and boosting anti-tumor immunity. Citation Format: Mohammad Ali Amini, Azhar Abbasi, Ping Cai, Hoyin Lip, Jason Li, Claudia Gordijo, Li Zhang, Michael Rauth, Xiao Yu Wu. Boosting doxorubicin-induced immunogenic cell death by using tumor microenvironment modulating nanoparticles [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 5218.

Published
2018

18. Glucose-Responsive Bioinorganic Nanohybrid Membrane for Self-Regulated Insulin Release

Author

Adam J. Shuhendler, Claudia R. Gordijo, and Xiao Yu Wu

Subjects
chemistry.chemical_classification, Materials science, biology, Insulin, medicine.medical_treatment, Bioinorganic chemistry, Permeation, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, Biomaterials, Enzyme, Membrane, chemistry, Biochemistry, Self-healing hydrogels, Electrochemistry, biology.protein, medicine, Glucose oxidase, Bovine serum albumin
Abstract

A bioinorganic nanohybrid glucose-responsive membrane is developed for self-regulated insulin delivery analogous to a healthy human pancreas. The application of MnO2 nanoparticles as a multifunctional component in a glucose-responsive, protein-based membrane with embedded pH-responsive hydrogel nanoparticles is proposed. The bio-nanohybrid membrane is prepared by crosslinking bovine serum albumin (BSA)–MnO2 nanoparticle conjugates with glucose oxidase and catalase in the presence of poly(N-isopropyl acrylamide-co-methacrylic acid) nanoparticles. The preparation and performance of this new nanocomposite material for a glucose-responsive insulin release system is presented. The activity and stability of immobilized glucose oxidase and the morphology and mechanical properties of the membrane are investigated. The enzymatic activity is well preserved in the membranes. The use of MnO2 nanoparticles not only reinforces the mechanical strength and the porous structure of the BSA-based membrane, but enhances the long-term stability of the enzymes. The in vitro release of insulin across the membrane is modulated by changes in glucose concentration mimicking possible fluctuations of blood-glucose level in diabetic patients. A four-fold increase in insulin permeation is observed when the glucose concentration is increased from normal to hyperglycemic levels, which returns to the baseline level when the glucose concentration is reduced to a normal level.

Published
2010

19. Manganese oxide and docetaxel co-loaded fluorescent polymer nanoparticles for dual modal imaging and chemotherapy of breast cancer

Author

Preethy Prasad, Xiao Yu Wu, Azhar Z. Abbasi, Warren D. Foltz, Mohammad Ali Amini, Chunsheng He, Ping Cai, Claudia R. Gordijo, and Andrew M. Rauth

Subjects
Fluorescence-lifetime imaging microscopy, Polymers, Pharmaceutical Science, Nanoparticle, Nanotechnology, Antineoplastic Agents, Breast Neoplasms, 02 engineering and technology, Docetaxel, Mice, SCID, 010402 general chemistry, 01 natural sciences, Cell Line, Tumor, Fluorescence microscope, medicine, Animals, Humans, Tissue Distribution, Particle Size, Cytotoxicity, Fluorescent Dyes, Chemistry, Magnetic Phenomena, Oxides, 021001 nanoscience & nanotechnology, Fluoresceins, Fluorescence, Magnetic Resonance Imaging, 0104 chemical sciences, Tumor Burden, Drug Liberation, Manganese Compounds, Microscopy, Fluorescence, Cancer cell, Drug delivery, Biophysics, Nanoparticles, Female, Taxoids, 0210 nano-technology, medicine.drug
Abstract

Multifunctional nanoparticles (NPs) have found important applications in diagnosis, chemotherapy, and image-guided surgery of tumors. In this work, we have developed polymeric theranostic NPs (PTNPs) containing the anticancer drug docetaxel (DTX), a fluorescent dye, and magnetic manganese oxide (MnO) NPs for dual modal imaging and chemotherapy. PTNPs ~150 nm in diameter were synthesized by co-loading hydrophobic DTX and MnO NPs ~5 nm in diameter, into the matrix of a fluorescent dye-labeled amphiphilic polymer. The PTNPs enabled high loading efficiency and sustained in vitro release of DTX. Energy-dependent cellular uptake and extended cytoplasmic retention of the PTNPs in MDA-MB-231 human breast cancer cells were observed by fluorescence microscopy examination. DTX-loaded PTNPs exhibited higher cytotoxicity than free DTX with a 3 to 4.4-fold decrease in drug dose required for 50% cell growth inhibition. The hydrophilic backbone of the amphiphilic polymer improved the fluidity of PTNPs which enhanced the longitudinal relaxivity (r1) of loaded MnO NPs by 2.7-fold with r1=2.4mM(-1)s(-1). Whole body fluorescence imaging (FI) and magnetic resonance imaging (MRI) showed significant accumulation and prolonged retention of PTNPs in orthotopic MDA-MB-231 breast tumors. These results suggest that the new amphiphilic polymer-based PTNP system, able to simultaneously deliver a poorly soluble anticancer drug, enhance MRI contrast, and stain tumor tissue by fluorescence, is a good candidate for cancer theranostic applications.

Published
2014

20. Multifunctional albumin-MnO₂ nanoparticles modulate solid tumor microenvironment by attenuating hypoxia, acidosis, vascular endothelial growth factor and enhance radiation response

Author

Preethy, Prasad, Claudia R, Gordijo, Azhar Z, Abbasi, Azusa, Maeda, Angela, Ip, Andrew Michael, Rauth, Ralph S, DaCosta, and Xiao Yu, Wu

Subjects
Models, Molecular, Vascular Endothelial Growth Factor A, Protein Conformation, Biological Transport, Oxides, Serum Albumin, Bovine, Hydrogen Peroxide, Hydrogen-Ion Concentration, Hypoxia-Inducible Factor 1, alpha Subunit, Radiation Tolerance, Cell Hypoxia, Oxygen, Mice, Drug Stability, Manganese Compounds, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Nanoparticles, Cattle, Acidosis
Abstract

Insufficient oxygenation (hypoxia), acidic pH (acidosis), and elevated levels of reactive oxygen species (ROS), such as H2O2, are characteristic abnormalities of the tumor microenvironment (TME). These abnormalities promote tumor aggressiveness, metastasis, and resistance to therapies. To date, there is no treatment available for comprehensive modulation of the TME. Approaches so far have been limited to regulating hypoxia, acidosis, or ROS individually, without accounting for their interdependent effects on tumor progression and response to treatments. Hence we have engineered multifunctional and colloidally stable bioinorganic nanoparticles composed of polyelectrolyte-albumin complex and MnO2 nanoparticles (A-MnO2 NPs) and utilized the reactivity of MnO2 toward peroxides for regulation of the TME with simultaneous oxygen generation and pH increase. In vitro studies showed that these NPs can generate oxygen by reacting with H2O2 produced by cancer cells under hypoxic conditions. A-MnO2 NPs simultaneously increased tumor oxygenation by 45% while increasing tumor pH from pH 6.7 to pH 7.2 by reacting with endogenous H2O2 produced within the tumor in a murine breast tumor model. Intratumoral treatment with NPs also led to the downregulation of two major regulators in tumor progression and aggressiveness, that is, hypoxia-inducible factor-1 alpha and vascular endothelial growth factor in the tumor. Combination treatment of the tumors with NPs and ionizing radiation significantly inhibited breast tumor growth, increased DNA double strand breaks and cancer cell death as compared to radiation therapy alone. These results suggest great potential of A-MnO2 NPs for modulation of the TME and enhancement of radiation response in the treatment of cancer.

Published
2014

21. Abstract 745: Hybrid bioactive nanoparticles for modulating prostate tumor microenvironment and enhancing radiation therapy

Author

Azhar Z. Abbasi, Andrew M. Rauth, Claudia R. Gordijo, Mohammad Ali Amini, Ping Cai, Xiao Yu Wu, and Robert G. Bristow

Subjects
Oncology, Cancer Research, medicine.medical_specialty, Biodistribution, Tumor microenvironment, Tumor hypoxia, Chemistry, medicine.medical_treatment, medicine.disease, Radiation therapy, Prostate cancer, medicine.anatomical_structure, Prostate, Internal medicine, Cancer research, medicine, Radiosensitivity, Ex vivo
Abstract

Introduction Tumor hypoxia is a poor prognostic factor in a number of malignancies such as prostate cancer (PCa). Clinically relevant hypoxic levels are detected in 30-90% PCa with oxygen concentrations below that required for half-maximal radiosensitivity, thus making radiotherapy (RT) ineffective alone [10]. Recently our lab has created pharmaceutically acceptable bioreactive hybrid manganese dioxide nanoparticles (MDNPs) and demonstrated their ability to modulate tumor microenvironment (TME) by reacting with H2O2 and protons and producing O2 in hypoxic tumors, as well as to enhance radiation response of tumor. Methods Lipid encapsulated and polymer stabilizedMDNPs (LMD NPs) were prepared by dispersing MnO2 precursor particles in melted lipid and polymer and then characterized for the particle size and zeta potential. In-vitro oxygen generation of LMD NPs was examined by measuring oxygen saturation level (sO2) in the blood using photoacoustic (PA) imaging method with addition of LMD NPs and H2O2. Biodistribution of LMD NPs in PCa tumor-bearing mice was evaluated by using a Xenogen IVIS Spectrum Imaging System following IV injection of ICG labeled NPs through the tail vein. Mice were monitored non-invasively for up to 24 hours. To investigate the effect of combination of MDNPs and radiation therapy on tumor growth delay and survival, PCa tumor-bearing mice were treated intravenously with LMD NPs with saline as a control. Four hour post injection, 10 Gy radiation dose was given at the site of the tumor. Mice were monitored every 2 days by measuring tumor size using a caliper. Mice were sacrificed when the tumor size reached 500 mm3. Results PA imaging demonstrated a controlled and prolonged generation of O2 in the blood with maximum oxygen saturation (90-95%) being reached within 60 min after incubation with LMD NPs and H2O2. The biodistribution and ex-vivo images of the resected organs showed that LMD NPs accumulated in the prostate tumor sites within 1 h post i.v. injection and remained in the tumor for at least 24 h. The ex vivo optical data of excised tissue showed a significant uptake of LMD nanoparticles by prostate tumor 24 hpost particle administration. The combination of LMD NPs treatment with single dose 10 Gy RT inhibited tumor growth by 24% at 5 days post treatment, whereas the tumor size increased about 47% in mice treated with RT alone. LMD NPs plus RT also improved survival rate of the cancerous mice for up to 53 days, which was about 3.3-fold enhancement in the mean survival rate compared to saline plus RT treatment (30 days). Conclusion The new bioreactive MnO2 NPs exhibited desirable oxygen- generating profile and high tumor accumulation and retention after systemic administration. This work has demonstrated, in a preclinical prostate tumor model, that the combination of LMD NPs with radiation therapy is a promising treatment approach for solid tumor.. Citation Format: Mohammad Ali Amini, Azhar Z. Abbasi, Claudia R. Gordijo1, Ping Cai, Andrew M. Rauth, Robert G. Bristow, Xiao Yu Wu. Hybrid bioactive nanoparticles for modulating prostate tumor microenvironment and enhancing radiation therapy. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 745.

Published
2016

22. In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats

Author

Xiao Yu Wu, Michael K.L. Chu, Jian Chen, Yu Sun, Khajag Koulajian, Alexander Ivovic, Simon Chiang, Adria Giacca, and Claudia R. Gordijo

Subjects
Cell Membrane Permeability, medicine.medical_treatment, Biomedical Engineering, Metal Nanoparticles, Bioengineering, Carbohydrate metabolism, Biochemistry, Hydrogel, Polyethylene Glycol Dimethacrylate, Diabetes Mellitus, Experimental, Glucose Oxidase, In vivo, Diabetes mellitus, medicine, Animals, Insulin, Glucose oxidase, Dimethylpolysiloxanes, Serum Albumin, Drug Carriers, biology, Chemistry, Albumin, Membranes, Artificial, Oxides, General Chemistry, Hydrogen-Ion Concentration, Microfluidic Analytical Techniques, medicine.disease, Catalase, In vitro, Rats, Glucose, Manganese Compounds, biology.protein, Biosensor, Biomedical engineering
Abstract

We have developed glucose-responsive implantable microdevices for closed-loop delivery of insulin and conducted in vivo testing of these devices in diabetic rats. The microdevices consist of an albumin-based bioinorganic membrane that utilizes glucose oxidase (GOx), catalase (CAT) and manganese dioxide (MnO(2)) nanoparticles to convert a change in the environmental glucose level to a pH stimulus, which regulates the volume of pH-sensitive hydrogel nanoparticles and thereby the permeability of the membrane. The membrane is integrated with microfabricated PDMS (polydimethylsiloxane) structures to form compact, stand-alone microdevices, which do not require tethering wires or tubes. During in vitro testing, the microdevices showed glucose-responsive insulin release over multiple cycles at clinically relevant glucose concentrations. In vivo, the microdevices were able to counter hyperglycemia in diabetic rats over a one-week period. The in vitro and in vivo testing results demonstrated the efficacy of closed-loop biosensing and rapid response of the 'smart' insulin delivery devices.

Published
2012

23. Hybrid quantum dot−fatty ester stealth nanoparticles: toward clinically relevant in vivo optical imaging of deep tissue

Author

Behrouz Soroushian, Peter J. O'Brien, Kui Yu, Adam J. Shuhendler, Andrew M. Rauth, Claudia R. Gordijo, Ho-Ka Carol Chan, Preethy Prasad, Xiao Yu Wu, and Michael C. Kolios

Subjects
Photoluminescence, Materials science, Fluorophore, breast tumor model, General Physics and Astronomy, Quantum yield, Nanoparticle, Mice, Nude, Nanotechnology, Breast Neoplasms, hybrid quantum dot−fatty ester nanoparticles, Photochemistry, chemistry.chemical_compound, Mice, deep tissue penetration, Nanocapsules, In vivo, Cell Line, Tumor, Quantum Dots, Animals, Humans, General Materials Science, near-infrared whole-body imaging, Fatty Acids, technology, industry, and agriculture, General Engineering, Chemical modification, equipment and supplies, Rats, chemistry, Nanocrystal, Microscopy, Fluorescence, Quantum dot, high biocompatibility
Abstract

Despite broad applications of quantum dots (QDs) in vitro, severe toxicity and dominant liver uptake have limited their clinical application. QDs that excite and emit in the ultraviolet and visible regions have limited in vivo applicability due to significant optical interference exerted by biological fluids and tissues. Hence we devised a new biocompatible hybrid fluorophore composed of near-infrared-emitting PbSe quantum dots encapsulated in solid fatty ester nanoparticles (QD-FEN) for in vivo imaging. The quantum yield and tissue penetration depth of the QD-FEN were characterized, and their biological fate was examined in a breast tumor-bearing animal model. It was found for the first time that chemical modification of the headgroup of QD-encapsulating organic fatty acids was a must as these groups quenched the photoluminescence of PbSe nanocrystals. The use of fatty esters enhanced aqueous quantum yields of PbSe QDs up to ∼45%, which was 50% higher than that of water-soluble PbSe nanocrystals in an aqueous medium. As a result, a greater than previously reported tissue penetration depth of fluorescence was recorded at 710 nm/840 nm excitation/emission wavelengths. The QD-FEN had much lower short-term cytotoxicity compared to nonencapsulated water-soluble QDs. More importantly, reduced liver uptake, increased tumor retention, lack of toxic response, and nearly complete clearance of QD-FEN from the tested animals was demonstrated. With a combination of near-infrared spectral properties, enhanced optical properties,and significantly improved biosafety profile, this novel hybrid nanoparticulate fluorophore system demonstrably provides real-time, deep-tissue fluorescent imaging of live animals, laying a foundation for further development toward clinical application.

Published
2012

24. Scanning Thermal Profiler

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

25. Surface Forces Apparatus

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

26. Small angle X-Ray Scattering in Grazing Incidence Geometry

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

27. Scanning Force Microscopy in Liquids

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

28. Seebeck Effect

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

29. SEM

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

30. Si Nanotubes

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

31. Subwavelength Antireflective Surfaces Arrays

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

32. Spectroscopic Techniques

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

33. Solid Lipid Nanospheres

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

34. Self-Regeneration

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

35. Sense Organ

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

36. Scanning Near-Field Optical Microscopy

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

37. Small-Angle Neutron Scattering

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

38. Structure and Stability of Protein Materials

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

39. Solid Lipid-Based Nanoparticles

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

40. Scanning Tunneling Microscopy

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

41. Self-Assembled Monolayers

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

42. Surface Tension and Chemical Potential at Nanoscale

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

43. Shark Skin Effect

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

44. Smart Carbon Nanotube-Polymer Composites

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

45. siRNA Delivery

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

46. Soil/Terrestrial Ecosystem/Terrestrial Compartment

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

47. Strain Gradient Plasticity Theory

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

48. Small Unilamellar Vesicle (SUV)

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

49. Spontaneous Polarization

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

50. Self-Assembly for Heterogeneous Integration of Microsystems

Author

Yimei Zhu, Hiromi Inada, Achim Hartschuh, Li Shi, Ada Della Pia, Giovanni Costantini, Amadeo L. Vázquez de Parga, Rodolfo Miranda, Antoine Barbier, Cristian Mocuta, Rachid Belkhou, Bharat Bhushan, J. H. Hoo, K. S. Park, R. Baskaran, K. F. Böhringer, Wei Lu, Michael Nosonovsky, Moon-Ho Ham, Ardemis A. Boghossian, Jong Hyun Choi, Michael S. Strano, Amy Lang, Maria Laura Habegger, Philip Motta, Thomas Bachmann, Hermann Wagner, Donald W. Brenner, Jian Chen, Nika Shakiba, Qingyuan Tan, Yu Sun, Julia R. Greer, M. Laver, S. M. Khaled, Alessandro Parodi, Ennio Tasciotti, Bakul C. Dave, Sarah B. Lockwood, Claudia Musicanti, Paolo Gasco, Fritz Vollrath, Alexander Booth, Andy C. McIntosh, Novid Beheshti, Richard Walker, Lars Uno Larsson, Andrew Copestake, Hyundoo Hwang, Yoon-Kyoung Cho, Michael Chu, Claudia R. Gordijo, Xiao Yu Wu, Mathias Kolle, Ullrich Steiner, Szu-Wen Wang, Frederik Ceyssens, Robert Puers, Xiaodong Han, Shengcheng Mao, Ze Zhang, Lei Jiang, Ling Lin, Regina Ragan, Vanni Lughi, Carlos Drummond, Marina Ruths, Weiqiang Mu, John B. Ketterson, Pierre Berini, Ya-Pu Zhao, Feng-Chao Wang, Shaurya Prakash, Simon J. Henley, José V. Anguita, S. Ravi P. Silva, Munish Chanana, Cintia Mateo, Verónica Salgueirino, Miguel A. Correa-Duarte, Swastik Kar, Saikat Talapatra, Javier Calvo Fuentes, José Rivas, M. Arturo López-Quintela, and Soichiro Tsuda

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results