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The article extends J. S. McMullen's 2024 entrepreneurial growth model inspired by the novel and the film "The Martian", arguing that incorporating AI and 3D printing into a closed-system environment allows for continuous, rather than just survival-driven, growth. It proposes that labor substitution, independent knowledge generation, and structural capital transformation can drive exponential growth, unlike McMullen’s entropy-limited model. By focusing on human desires for comfort and long-term innovation cycles, the model envisions sustained wealth creation even in constrained environments.

Polytraumatic injuries, specifically long bone fracture and traumatic brain injury (TBI), frequently occur together. Clinical observation has long held that TBI can accelerate fracture healing, yet the complexity and heterogeneity of these injuries has produced conflicting data with limited information on underlying mechanisms. We developed a murine polytrauma model with TBI and fracture to evaluate healing in a controlled system. Fractures were created both contralateral and ipsilateral to the TBI to test whether differential responses of humoral and/or neuronal systems drove altered healing patterns. Our results show increased bone formation after TBI when injuries occur contralateral to each other, rather than ipsilateral, suggesting a role of the nervous system based on the crossed neuroanatomy of motor and sensory systems. Analysis of the humoral system shows that blood cell counts and inflammatory markers are differentially modulated by polytrauma. A data-driven multivariate analysis integrating all outcome measures showed a distinct pathological state of polytrauma and co-variations between fracture, TBI and systemic markers. Taken together, our results suggest that a contralateral bone fracture and TBI alter the local neuroinflammatory state to accelerate early fracture healing. We believe applying a similar data-driven approach to clinical polytrauma may help to better understand the complicated pathophysiological mechanisms of healing.

International entrepreneurship—the field dedicated to the discovery, enactment, evaluation, and exploitation of opportunities across national borders to create future goods and services—is as inextricably linked to firm activity as entrepreneurship, strategy, or international business. However, for much of the past 30 years the field has been hampered by confusion and inconsistency over definitions and existential questions such as, "What is a born global?"; "what is an international new venture?"; and "how does one distinguish emerging firm types?" While many of these questions have been previously answered in isolation, confusion remains, as the field lacks a coherent unified perspective of firm activity. In this introduction to our thematic issue on international entrepreneurship, we address this need, present a unified model of international new ventures drawn from the latest definitions and distinctions, and call for future research that fully integrates form into the conversations of opportunity, technology, liability, and the unique network and value-chain alignments that exist across borders. We also discuss how we can better integrate and add value to nascent trends more broadly from neuroscience, deglobalization, intercultural arbitrage, and other areas. [ABSTRACT FROM AUTHOR]

Entrepreneurial orientation (EO) is an important construct in the fields of management and entrepreneurship research. Interest in EO knowledge continues to thrive with a burgeoning research agenda in multiple contexts and with diverse implications. However, a subset of this research, which endeavors to apply the EO construct to explain or predict individuals' entrepreneurial beliefs and behaviors, has met with resistance. This paper examines the case for EO at the individual level (Ind.EO). We consider the EO legacy concerns, and the various theoretical implications and benefits of doing so. Drawing upon an "EO as a family of constructs" framework, we propose paths forward for studying Ind.EO credibly, consistent with, but distinct from, traditional firm-level EO. Finally, we outline a research agenda and discuss the contributions and potential implications for Ind.EO research across the wider entrepreneurship discipline. [ABSTRACT FROM AUTHOR]

We propose and test a process where potential entrepreneurs (PEs) prioritize a venture idea consideration set using preference-based decision-specific heuristics to assess idea feasibility and desirability. We test our hypotheses through two studies with PEs. The first experiment shows that prioritization occurs, with 113 of 122 PEs voluntarily changing a randomized list of their ideated ventures into a rank-ordered priority list of potential opportunities. Second, we employ a novel "equivocal forced-choice" conjoint design with 250 PEs. We find empirical support that PEs prioritize via relative preferences for experience-based knowledge, strong social ties, and low risk/low reward venture ideas. We contribute to the entrepreneurship literature by theorizing and providing evidence of a prioritization stage for multiple idea sets before evaluation. Further, we demonstrate the influence of individual and social network factors on prioritization and expand our understanding of how PEs conceptualize risk in venturing. [ABSTRACT FROM AUTHOR]

Proton-conducting oxides, such as BaZr0.9Y0.1O3−δ (BZY10), are receiving significant scientific attention for application in a variety of electrochemical applications. It has been shown that the synthesis route has a significant effect on the ionic behavior of these materials, especially the grain boundaries (GB). In this study, laser-pulsed atom probe tomography (APT) is used to characterize the GB chemistry of BZY10 samples prepared by four different methods: (1) spark plasma sintering (SPS), (2) conventional sintering followed by high-temperature annealing (HT), (3) conventional sintering with NiO used as a sintering aid (SSR-Ni), and (4) solid-state reactive sintering of oxide precursor powders with NiO as a reactive sintering aid (SSRS-Ni). Oxygen depletion (corresponding to oxygen vacancy accumulation) was observed at every GB in this study, consistent with the positive space-charge GB region commonly assigned to these materials. In contrast to the consistent trends associated with oxygen depletion, cation constituents showed varying segregation/depletion behaviors. The samples that used NiO revealed Ni preferentially segregating to the GB. The most common impurities in BZY10 are Al, Fe, Mg, Si, and Sr, all of which generally accumulate at GBs. In order to quantify these chemical trends, the APT method was optimized for this material supplemented with understanding from density functional theory (DFT). This APT study reveals the complexity of BZY10 GB chemistry and shows that even adjacent GBs in the same material can sometimes show surprisingly different GB chemistry. [ABSTRACT FROM AUTHOR]

Research on entrepreneurial mindset (EM) has proliferated in recent years. Its importance rests on a key assumption: EM matters for entrepreneurial behavior. However, to date, EM conceptualizations remain fragmented, and theories delineating the relationship between EM and the behaviors underpinning entrepreneurship are limited. In this article, we conceptualize EM as a goal orientation formed through dispositional beliefs about entrepreneurship and opportunity beliefs, which results in entrepreneurial behaviors. We draw upon recent advances in entrepreneurial orientation (EO) research at the individual level as a model for dispositional beliefs. Further, we theorize the origins, mechanisms, manifestations, and effect of EM. Finally, we discuss important implications for stakeholders interested in leveraging EM to stimulate entrepreneurial activity and lay out a research agenda for future development of our disposition-based framework. [ABSTRACT FROM AUTHOR]

New ventures that internationalize aggressively from or near founding have been of continued interest in international entrepreneurship. A rich literature now exists in which researchers make numerous distinctions between types or subcategories of rapidly internationalizing firms and how these relate to nuances in performance outcomes. Conversely, little progress has been made toward a theoretical understanding of why these seemingly unique firms emerge in the first place. We contend that a key question remains unanswered: Why do some entrepreneurs from the outset compound the liability of newness, inherent in entrepreneurship, with the liability of foreignness, inherent in internationalization? Drawing from social cognitive careers theory, we developed a model explaining the emergence of entrepreneurial intentions to found explicitly global ventures. We tested our model across two distinct studies, using a multiwave multicountry approach, and found consistent support for an interest pathway to these entrepreneurial intentions. The simple, yet novel, implication is that noneconomic logic shaping entrepreneurs' vocational choices can help explain why some founders take additional risks by overtly focusing on aggressive global growth from inception. [ABSTRACT FROM AUTHOR]