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1. Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML

Author

Leire Iralde-Lorente, Giusy Tassone, Ylenia Cau, Claire Munier, Lorenzo Franci, Cecilia Pozzi, Adriano Angelucci, Mario Chiariello, Matthew Perry, Stefano Mangani, and Maurizio Botta

Subjects
14-3-3, Protein-protein interactions, c-Abl, chronic myeloid leukemia (CML), General Works
Abstract

c-Abl is a tyrosine kinase implicated in the regulation of proliferation, adhesion, motility, andcell survival [...]

Published
2019
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