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1. Elevations in High-Sensitive Cardiac Troponin T and N-Terminal Prohormone Brain Natriuretic Peptide Levels in the Serum Can Predict the Development of Anthracycline-Induced Cardiomyopathy

Author

Bisoc, Alina, Ciurescu, Daniel, Rădoi, Mariana, Tântu, Monica M, Rogozea, Liliana, Sweidan, Alexander J, and Bota, Daniela A

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Cancer, Cardiovascular, Heart Disease, 4.2 Evaluation of markers and technologies, Detection, screening and diagnosis, Adult, Aged, Anthracyclines, Antineoplastic Agents, Biomarkers, Cardiomyopathies, Doxorubicin, Echocardiography, Female, Humans, Male, Middle Aged, Natriuretic Peptide, Brain, Neoplasms, Predictive Value of Tests, Prospective Studies, Protein Precursors, Stroke Volume, Treatment Outcome, Troponin T, Young Adult, anthracycline-induced cardiomyopathy, hs-cTnT, NT-proBNP, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundAnthracyclines remain the cornerstone of the treatment in many cancers including lymphomas, leukemia and sarcomas, and breast cancer. The cardiomyopathy that develops from anthracyclines can lead to heart failure and decreased survival. Multiple mechanisms are involved in the pathophysiology of anthracycline-induced heart failure.Study questionWe hypothesize that anthracycline-induced cardiac (AIC) pathology can be monitored using a panel of blood biomarkers including high-sensitive cardiac troponin T (hs-cTnT) for myocyte necrosis and N-terminal prohormone brain natriuretic peptide (NT-proBNP) for parietal stress.Study designA prospective, institutionally approved study recruited all patients with cancer scheduled to start anthracycline chemotherapy in the Transylvania University cancer clinics.Measures and outcomesTransthoracic 2D echocardiography and the measurements of NT-proBNP and hs-cTnT plasma levels were performed at the beginning of the study and 3 months and 6 months after anthracycline treatment initiation.ResultsThe plasma levels of hs-cTnT at 3 months (rho = 0.439, P = 0.0001) and 6 months (rho = 0.490, P = 0.0001) are correlated with AIC occurrence. For a cutoff value of hs-cTnT at 3 months > 0.008 ng/mL, we obtained 66.7% sensitivity and 67.9% specificity for developing AIC at 6 months, with a 54.5% positive predictive value and a 87.8% negative predictive value. The NT-proBNP serum levels at 3 months (rho = 0.495, P = 0.0001) and 6 months (rho = 0.638, P = 0.0001) are correlated with an AIC diagnosis at 6 months. For a cutoff value of NT-proBNP at 3 months >118.5 pg/mL, we obtained 80% sensitivity and 79.2% specificity for evolution to AIC at 6 months, with 52.2% positive predictive value and 93.3% negative predictive value.ConclusionsIn anthracycline-treated cancer patients, the increase in plasma levels of NT-proBNP and of hs-cTnT can predict the development of anthracycline-induced cardiomyopathy. Early identification of at-risk patients will potentially allow for targeted dose reductions and will diminish the number of patients developing cardiac pathology.

Published
2020

3. Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Author

Adamchuk, Grigory, Ahn, Myung-Ju, Alexandru, Aurelia, Altundag, Ozden, Alyasova, Anna, Andrusenko, Orest, Aoe, Keisuke, Araujo, Antonio, Aren, Osvaldo, Arrieta Rodriguez, Oscar, Ativitavas, Touch, Avendano, Oscar, Barata, Fernando, Barrios, Carlos Henrique, Beato, Carlos, Bergstrom, Per, Betticher, Daniel, Bolotina, Larisa, Bondarenko, Igor, Botha, Michiel, Buddu, Sayeuri, Caglevic, Christian, Cardona, Andres, Castro, Gilberto, Jr, Castro, Hugo, Cay Senler, Filiz, Cerny, Carlos Alexandre Sydow, Cesas, Alvydas, Chan, Gee-Chen, Chang, Jianhua, Chen, Gongyan, Chen, Xi, Cheng, Susanna, Cheng, Ying, Cherciu, Nelly, Chiu, Chao-Hua, Cho, Byoung Chul, Cicenas, Saulius, Ciurescu, Daniel, Cohen, Graham, Costa, Marcos Andre, Danchaivijitr, Pongwut, De Angelis, Flavia, de Azevedo, Sergio Jobim, Dediu, Mircea, Deliverski, Tsvetan, De Marchi, Pedro Rafael Martins, de The Bustamante Valles, Flor, Ding, Zhenyu, Doganov, Boyan, Dreosti, Lydia, Duarte, Ricardo, Edusma-Dy, Regina, Emelyanov, Sergey, Erman, Mustafa, Fan, Yun, Fein, Luis, Feng, Jifeng, Fenton, David, Fernandes, Gustavo, Ferreira, Carlos, Franke, Fabio Andre, Freitas, Helano, Fujisaka, Yasuhito, Galindo, Hector, Galvez, Christina, Ganea, Doina, Gil, Nuno, Girotto, Gustavo, Goker, Erdem, Goksel, Tuncay, Gomez Aubin, Gonzalo, Gomez Wolff, Luis, Griph, Hakan, Gumus, Mahmut, Hall, Jacqueline, Hart, Gregory, Havel, Libor, He, Jianxing, He, Yong, Hernandez Hernandez, Carlos, Hespanhol, Venceslau, Hirashima, Tomonori, Ho, Chung Man James, Horiike, Atsushi, Hosomi, Yukio, Hotta, Katsuyuki, Hou, Mei, How, Soon Hin, Hsia, Te-Chun, Hu, Yi, Ichiki, Masao, Imamura, Fumio, Ivashchuk, Oleksandr, Iwamoto, Yasuo, Jaal, Jana, Jassem, Jacek, Jordaan, Christa, Juergens, Rosalyn Anne, Kaen, Diego, Kalinka-Warzocha, Ewa, Karaseva, Nina, Karaszewska, Boguslawa, Kazarnowicz, Andrzej, Kasahara, Kazuo, Katakami, Nobuyuki, Kato, Terufumi, Kawaguchi, Tomoya, Kim, Joo Hang, Kishi, Kazuma, Kolek, Vitezslav, Koleva, Marchela, Kolman, Petr, Koubkova, Leona, Kowalyszyn, Ruben, Kowalski, Dariusz, Koynov, Krassimir, Ksienski, Doran, Kubota, Kaoru, Kudaba, Iveta, Kurata, Takayasu, Kuusk, Gerli, Kuzina, Lyudmila, Laczo, Ibolya, Ladrera, Guia Elena Imelda, Laktionov, Konstantin, Landers, Gregory, Lazarev, Sergey, Lerzo, Guillermo, Lesniewski Kmak, Krzysztof, Li, Wei, Liam, Chong Kin, Lifirenko, Igor, Lipatov, Oleg, Liu, Xiaoqing, Liu, Zhe, Lo, Sing Hung, Lopes, Valeria, Lopez, Karla, Lu, Shun, Martinengo, Gaston, Mas, Luis, Matrosova, Marina, Micheva, Rumyana, Milanova, Zhasmina, Miron, Lucian, Mok, Tony, Molina, Matias, Murakami, Shuji, Nakahara, Yasuharu, Nguyen, Tien Quang, Nishimura, Takashi, Ochsenbein, Adrian, Ohira, Tatsuo, Ohman, Ronny, Ong, Choo Khoon, Ostoros, Gyula, Ouyang, Xuenong, Ovchinnikova, Elena, Ozyilkan, Ozgur, Petruzelka, Lubos, Pham, Xuan Dung, Picon, Pablo, Piko, Bela, Poltoratsky, Artem, Ponomarova, Olga, Popelkova, Patrice, Purkalne, Gunta, Qin, Shukui, Ramlau, Rodryg, Rappaport, Bernardo, Rey, Felipe, Richardet, Eduardo, Roubec, Jaromir, Ruff, Paul, Rusyn, Andrii, Saka, Hideo, Salas, Jorge, Sandoval, Mario, Santos, Lucas, Sawa, Toshiyuki, Seetalarom, Kasan, Seker, Mesut, Seki, Nobuhiko, Seolwane, Freddy, Shepherd, Lucinda, Shevnya, Sergii, Shimada, Andrea Kazumi, Shparyk, Yaroslav, Sinielnikov, Ivan, Sirbu, Daniela, Smaletz, Oren, Soares, Joao Paulo Holanda, Sookprasert, Aumkhae, Speranza, Giovanna, Srimuninnimit, Vichien, Sriuranpong, Virote, Stara, Zinaida, Su, Wu-Chou, Sugawara, Shunichi, Szpak, Waldemar, Takahashi, Kazuhisa, Takigawa, Nagio, Tanaka, Hiroshi, Tan Chun Bing, Jerry, Tang, Qiyou, Taranov, Pavel, Tejada, Hermes, Tho, Lye Mun, Torii, Yoshitaro, Trukhyn, Dmytro, Turdean, Maria, Turna, Hande, Ursol, Grygoriy, Vanasek, Jaroslav, Varela, Mirta, Vallejo, Marcela, Vera, Luis, Victorino, Ana-Paula, Vlasek, Tomas, Vynnychenko, Ihor, Wang, Buhai, Wang, Jie, Wang, Kai, Wu, Yilong, Yamada, Kazuhiko, Yang, Chih-Hsin, Yokoyama, Takuma, Yokoyama, Toshihide, Yoshioka, Hiroshige, Yumuk, Fulden, Zambrano, Angela, Zarba, Juan Jose, Zarubenkov, Oleg, Zemaitis, Marius, Zhang, Li, Zhang, Xin, Zhao, Jun, Zhou, Caicun, Zhou, Jianying, Zhou, Qing, Zippelius, Alfred, Mok, Tony S K, Wu, Yi-Long, Kowalski, Dariusz M, Turna, Hande Z, Laktionov, Konstantin K, Lubiniecki, Gregory M, Zhang, Jin, Kush, Debra, and Lopes, Gilberto

Published
2019
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7. T-RAC: Study protocol of a randomised clinical trial for assessing the acceptability and preliminary efficacy of adding an exergame-augmented dynamic imagery intervention to the behavioural activation treatment of depression

Author

Tiba, Alexandru, primary, Drugaș, Marius, additional, Sârbu, Ioana, additional, Simona, Trip, additional, Bora, Carmen, additional, Miclăuș, Daiana, additional, Voss, Laura, additional, Sanislav, Ioana, additional, and Ciurescu, Daniel, additional

Published
2023
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10. New Trends in Uric Acid Electroanalysis.

Author

Chelmea, Ligia, Badea, Mihaela, Scarneciu, Ioan, Moga, Marius Alexandru, Dima, Lorena, Restani, Patrizia, Murdaca, Cecilia, Ciurescu, Daniel, and Gaman, Laura Elena

Subjects
ELECTROCHEMICAL analysis, MEDICAL research personnel, URIC acid, CLINICAL medicine, DETECTORS, HYPERURICEMIA
Abstract

Considering the increasing incidence of hyperuricemia and oxidative stress-related diseases, quantification of uric acid has become essential. Therefore, the evolution on sensing devices being favorable, these questions are more often addressed to the field of medical researchers. As for many metabolites, (bio)sensors provide a reliable method for screening and evaluation of uric acid status. Due to the numerous categories of (bio)sensors available, choosing the appropriate one is a challenge. This study reviews the scientific information concerning the most suitable (bio)sensors for quantification of uric acid, presenting a list of sensors from the last decade, categorized by configurations and materials. In addition, this review includes a comparison of sensors according to their interference behavior and sensitivity, offering an objective perspective for identifying devices that are suitable for clinical applications. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Adjunctive use of InGaAsP and Er,Cr:YSGG lasers in nonsurgical periodontal therapy: a randomized controlled clinical study.

Author

Ciurescu, Codruta Elena, Cosgarea, Raluca, Ciurescu, Daniel, Gheorghiu, Anca, Popa, Daniela, Franzen, Rene, Arweiler, Nicole B., Sculean, Anton, and Gutknecht, Norbert

Subjects
DIODES, PERIODONTAL disease treatment, CHRONIC disease treatment, LASER therapy, DEBRIDEMENT, TREATMENT effectiveness
Abstract

Objective: To evaluate clinically and microbiologically the outcomes following the combined application of InGaAsP diode laser and Er,Cr:YSGG laser for nonsurgical treatment of chronic periodontitis (ChP). Method and materials: Forty-two patients (age 45.31 ± 9.78 years, 22 female, 23 smokers) with ChP were randomly treated with subgingival debridement (SD) by means of ultrasonic and hand instruments (control group, n = 21) or with InGaAsP followed 1 week later by InGaAsP + SD + Er,Cr:YSGG (test group, n = 21). In the test group, a second laser treatment was performed for all residual sites (bleeding sites with probing depth [PD] ≥ 4 mm) 2 months after the first laser therapy. At baseline and 6 months after therapy, periodontal clinical and microbiologic parameters were evaluated. Results: Six months after therapy, statistically significant clinical and microbiologic improvements (PD reduction, clinical attachment level [CAL] gain, quantitative reduction of periopathogens) were observed in both groups compared to baseline. However, the use of InGaAsP followed by SD and the adjunctive use of an Er,Cr:YSGG laser, yielded statistically significantly higher clinical (PD, CAL, bleeding on probing, number of sites with PD ≥ 5 mm, PD ≥ 6 mm, PD ≥ 7 mm) and microbiologic (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, Peptostreptococcus micros, Fusobacterium nucleatum) improvements (P < .05) compared to SD alone. Conclusions: In patients with ChP, the adjunctive use of InGaAsP and Er,Cr:YSGG to SD may additionally improve the clinical and microbiologic parameters obtained with SD alone, thus representing a valuable approach in nonsurgical periodontal therapy. [ABSTRACT FROM AUTHOR]

Published
2019
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12. Efficacy of chemotherapy for pain control in patients at the onset of their disease.

Author

Spînu, Ștefan, Sur, Daniel, Creciun, Veronica, Moșoiu, Daniela, and Ciurescu, Daniel

Subjects
CANCER pain, BRIEF Pain Inventory, PAIN management, PATHOLOGY, CANCER chemotherapy
Abstract

Objective. The rationale of the present study is to measure the impact of antineoplastic treatment (chemotherapy) on the pain generated by the disease. Materials and method. The present study was based on the completion of two standardized questionnaires for the assessment of physical symptoms (Brief Pain Inventory [BPI] and revised Edmonton Symptom Assessment System [ESASr]) in three different moments. The research was carried out in the Prof. Dr. Ion Chiricuţă” Institute of Oncology, Cluj-Napoca, Romania, between 2022 and 2023. Results. Twenty-four patients were included in the study (18 men), and they received different cytostatic treatment regimens, adapted to the underlying pathology. We have analyzed first the distribution of all symptoms from the ESASr and the total score. In terms of the general situation, if we exclude pain, there is never a difference between Time 2 and Time 3. Furthermore, in all cases where there is a statistically significant effect, there is a difference between Time 1 and Time 3. We also analyzed the distribution of activities with which pain interacts – with BPI. Regarding the general situation, three patterns of influence of pain on the examined parameters are found: for general activity, mood, ability to work and sleep, there are significant differences between moments 1-2 and 1-3, without significant differences between moments 2-3. The second pattern identified refers to the lack of effect of pain on the ability to walk and on the relationship with other people. The peculiarity is represented by the influence on the enjoyment of life that was significantly improved only from Time 1 to Time 3, not between 1-2 or 2-3. Conclusions. The present study demonstrated a considerable effect of cytostatic treatment on the management of cancer-related pain, as shown across different evaluations. [ABSTRACT FROM AUTHOR]

Published
2024

14. Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Author

Mok, Tony S K, primary, Wu, Yi-Long, additional, Kudaba, Iveta, additional, Kowalski, Dariusz M, additional, Cho, Byoung Chul, additional, Turna, Hande Z, additional, Castro, Gilberto, additional, Srimuninnimit, Vichien, additional, Laktionov, Konstantin K, additional, Bondarenko, Igor, additional, Kubota, Kaoru, additional, Lubiniecki, Gregory M, additional, Zhang, Jin, additional, Kush, Debra, additional, Lopes, Gilberto, additional, Adamchuk, Grigory, additional, Ahn, Myung-Ju, additional, Alexandru, Aurelia, additional, Altundag, Ozden, additional, Alyasova, Anna, additional, Andrusenko, Orest, additional, Aoe, Keisuke, additional, Araujo, Antonio, additional, Aren, Osvaldo, additional, Arrieta Rodriguez, Oscar, additional, Ativitavas, Touch, additional, Avendano, Oscar, additional, Barata, Fernando, additional, Barrios, Carlos Henrique, additional, Beato, Carlos, additional, Bergstrom, Per, additional, Betticher, Daniel, additional, Bolotina, Larisa, additional, Botha, Michiel, additional, Buddu, Sayeuri, additional, Caglevic, Christian, additional, Cardona, Andres, additional, Castro, Hugo, additional, Cay Senler, Filiz, additional, Cerny, Carlos Alexandre Sydow, additional, Cesas, Alvydas, additional, Chan, Gee-Chen, additional, Chang, Jianhua, additional, Chen, Gongyan, additional, Chen, Xi, additional, Cheng, Susanna, additional, Cheng, Ying, additional, Cherciu, Nelly, additional, Chiu, Chao-Hua, additional, Cicenas, Saulius, additional, Ciurescu, Daniel, additional, Cohen, Graham, additional, Costa, Marcos Andre, additional, Danchaivijitr, Pongwut, additional, De Angelis, Flavia, additional, de Azevedo, Sergio Jobim, additional, Dediu, Mircea, additional, Deliverski, Tsvetan, additional, De Marchi, Pedro Rafael Martins, additional, de The Bustamante Valles, Flor, additional, Ding, Zhenyu, additional, Doganov, Boyan, additional, Dreosti, Lydia, additional, Duarte, Ricardo, additional, Edusma-Dy, Regina, additional, Emelyanov, Sergey, additional, Erman, Mustafa, additional, Fan, Yun, additional, Fein, Luis, additional, Feng, Jifeng, additional, Fenton, David, additional, Fernandes, Gustavo, additional, Ferreira, Carlos, additional, Franke, Fabio Andre, additional, Freitas, Helano, additional, Fujisaka, Yasuhito, additional, Galindo, Hector, additional, Galvez, Christina, additional, Ganea, Doina, additional, Gil, Nuno, additional, Girotto, Gustavo, additional, Goker, Erdem, additional, Goksel, Tuncay, additional, Gomez Aubin, Gonzalo, additional, Gomez Wolff, Luis, additional, Griph, Hakan, additional, Gumus, Mahmut, additional, Hall, Jacqueline, additional, Hart, Gregory, additional, Havel, Libor, additional, He, Jianxing, additional, He, Yong, additional, Hernandez Hernandez, Carlos, additional, Hespanhol, Venceslau, additional, Hirashima, Tomonori, additional, Ho, Chung Man James, additional, Horiike, Atsushi, additional, Hosomi, Yukio, additional, Hotta, Katsuyuki, additional, Hou, Mei, additional, How, Soon Hin, additional, Hsia, Te-Chun, additional, Hu, Yi, additional, Ichiki, Masao, additional, Imamura, Fumio, additional, Ivashchuk, Oleksandr, additional, Iwamoto, Yasuo, additional, Jaal, Jana, additional, Jassem, Jacek, additional, Jordaan, Christa, additional, Juergens, Rosalyn Anne, additional, Kaen, Diego, additional, Kalinka-Warzocha, Ewa, additional, Karaseva, Nina, additional, Karaszewska, Boguslawa, additional, Kazarnowicz, Andrzej, additional, Kasahara, Kazuo, additional, Katakami, Nobuyuki, additional, Kato, Terufumi, additional, Kawaguchi, Tomoya, additional, Kim, Joo Hang, additional, Kishi, Kazuma, additional, Kolek, Vitezslav, additional, Koleva, Marchela, additional, Kolman, Petr, additional, Koubkova, Leona, additional, Kowalyszyn, Ruben, additional, Kowalski, Dariusz, additional, Koynov, Krassimir, additional, Ksienski, Doran, additional, Kurata, Takayasu, additional, Kuusk, Gerli, additional, Kuzina, Lyudmila, additional, Laczo, Ibolya, additional, Ladrera, Guia Elena Imelda, additional, Laktionov, Konstantin, additional, Landers, Gregory, additional, Lazarev, Sergey, additional, Lerzo, Guillermo, additional, Lesniewski Kmak, Krzysztof, additional, Li, Wei, additional, Liam, Chong Kin, additional, Lifirenko, Igor, additional, Lipatov, Oleg, additional, Liu, Xiaoqing, additional, Liu, Zhe, additional, Lo, Sing Hung, additional, Lopes, Valeria, additional, Lopez, Karla, additional, Lu, Shun, additional, Martinengo, Gaston, additional, Mas, Luis, additional, Matrosova, Marina, additional, Micheva, Rumyana, additional, Milanova, Zhasmina, additional, Miron, Lucian, additional, Mok, Tony, additional, Molina, Matias, additional, Murakami, Shuji, additional, Nakahara, Yasuharu, additional, Nguyen, Tien Quang, additional, Nishimura, Takashi, additional, Ochsenbein, Adrian, additional, Ohira, Tatsuo, additional, Ohman, Ronny, additional, Ong, Choo Khoon, additional, Ostoros, Gyula, additional, Ouyang, Xuenong, additional, Ovchinnikova, Elena, additional, Ozyilkan, Ozgur, additional, Petruzelka, Lubos, additional, Pham, Xuan Dung, additional, Picon, Pablo, additional, Piko, Bela, additional, Poltoratsky, Artem, additional, Ponomarova, Olga, additional, Popelkova, Patrice, additional, Purkalne, Gunta, additional, Qin, Shukui, additional, Ramlau, Rodryg, additional, Rappaport, Bernardo, additional, Rey, Felipe, additional, Richardet, Eduardo, additional, Roubec, Jaromir, additional, Ruff, Paul, additional, Rusyn, Andrii, additional, Saka, Hideo, additional, Salas, Jorge, additional, Sandoval, Mario, additional, Santos, Lucas, additional, Sawa, Toshiyuki, additional, Seetalarom, Kasan, additional, Seker, Mesut, additional, Seki, Nobuhiko, additional, Seolwane, Freddy, additional, Shepherd, Lucinda, additional, Shevnya, Sergii, additional, Shimada, Andrea Kazumi, additional, Shparyk, Yaroslav, additional, Sinielnikov, Ivan, additional, Sirbu, Daniela, additional, Smaletz, Oren, additional, Soares, Joao Paulo Holanda, additional, Sookprasert, Aumkhae, additional, Speranza, Giovanna, additional, Sriuranpong, Virote, additional, Stara, Zinaida, additional, Su, Wu-Chou, additional, Sugawara, Shunichi, additional, Szpak, Waldemar, additional, Takahashi, Kazuhisa, additional, Takigawa, Nagio, additional, Tanaka, Hiroshi, additional, Tan Chun Bing, Jerry, additional, Tang, Qiyou, additional, Taranov, Pavel, additional, Tejada, Hermes, additional, Tho, Lye Mun, additional, Torii, Yoshitaro, additional, Trukhyn, Dmytro, additional, Turdean, Maria, additional, Turna, Hande, additional, Ursol, Grygoriy, additional, Vanasek, Jaroslav, additional, Varela, Mirta, additional, Vallejo, Marcela, additional, Vera, Luis, additional, Victorino, Ana-Paula, additional, Vlasek, Tomas, additional, Vynnychenko, Ihor, additional, Wang, Buhai, additional, Wang, Jie, additional, Wang, Kai, additional, Wu, Yilong, additional, Yamada, Kazuhiko, additional, Yang, Chih-Hsin, additional, Yokoyama, Takuma, additional, Yokoyama, Toshihide, additional, Yoshioka, Hiroshige, additional, Yumuk, Fulden, additional, Zambrano, Angela, additional, Zarba, Juan Jose, additional, Zarubenkov, Oleg, additional, Zemaitis, Marius, additional, Zhang, Li, additional, Zhang, Xin, additional, Zhao, Jun, additional, Zhou, Caicun, additional, Zhou, Jianying, additional, Zhou, Qing, additional, and Zippelius, Alfred, additional

Published
2019
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16. STUDII PRIVIND VARIAŢII ALE PROFILULUI LIPIDIC LA LOTURI DE NEFUMĂTORI, FUMĂTORI CU ŞI FĂRĂ PATOLOGII RESPIRATORII.

Author

Pârvu, Monica Andreea, Rogozea, Liliana, Alexandrescu, Dana, Ciurescu, Daniel, Rădoi, Mariana, and Badea, Mihaela

Abstract

Copyright of Brasov Medical Journal / Jurnal Medical Brasovean is the property of Transilvania University of Brasov, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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18. NIVELUL DE CUNOAŞTERE AL PROBLEMATICII CANCERULUI MAMAR. STUDIU EFECTUAT ÎN ANUL 2016 ÎN CENTRUL DE DIAGNOSTIC ŞI TRATAMENT ONCOLOGIC BRAŞOV.

Author

Simon, Mădălina Georgiana, Simon, Gabriela, Ciurescu, Daniel, Sechel, Gabriela, and Badea, Mihaela

Abstract

Breast cancer is a malignancy with a very high frequency in women, having several forms, the most common being followed by lobular carcinoma ductal carcinoma. The research team made and administered questionnaires with questions and suggested answers that covered various issues: status of health insurance, history of cancer in their families, the frequency of selfexamination breast, guiding self-examination of the breasts, frequency of performing ultrasound and mammography, sources of information concerning the prevention and the treatment of breast cancer, causes of breast cancer, reliability of oncologic system in Romania, the assessment of their health status. It was noticed that both healthy women and those diagnosed with breast cancer have confidence or trust in the medical oncology in Romania because it was observed that many patients with breast cancer were monitored and controlled by system oncology at long period of time. [ABSTRACT FROM AUTHOR]

Published
2017

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