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1. A gene expression-based classifier for HER2-low breast cancer

Author

Di Cosimo, Serena, Pizzamiglio, Sara, Ciniselli, Chiara Maura, Duroni, Valeria, Cappelletti, Vera, De Cecco, Loris, De Marco, Cinzia, Silvestri, Marco, De Santis, Maria Carmen, Vingiani, Andrea, Paolini, Biagio, Orlandi, Rosaria, Iorio, Marilena Valeria, Pruneri, Giancarlo, and Verderio, Paolo

Published
2024
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9. Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse

Author

Ciceri, Sara, Montalvão-de-Azevedo, Rafaela, Tajbakhsh, Amir, Bertolotti, Alessia, Spagnuolo, Rosalin Dolores, Boschetti, Luna, Capasso, Maria, D’Angelo, Paolo, Serra, Annalisa, Diomedi-Camassei, Francesca, Meli, Mariaclaudia, Nantron, Marilina, Quarello, Paola, Buccoliero, Anna Maria, Tamburini, Angela, Ciniselli, Chiara Maura, Verderio, Paolo, Collini, Paola, Radice, Paolo, Spreafico, Filippo, and Perotti, Daniela

Published
2021
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11. Periprosthetic effusions surrounding breast expander: a flow cytometric, immunohistochemical and molecular characterization

Author

Sala, Laura, primary, Ciniselli, Chiara Maura, additional, Bozzi, Fabio, additional, Summo, Valeria, additional, Bonini, Chiara, additional, Brich, Silvia, additional, Bertolotti, Alessia, additional, Viola, Trupia Desiré, additional, Volpi, Chiara Costanza, additional, Pizzamiglio, Sara, additional, Paolini, Biagio, additional, Aiello, Antonella, additional, Apolone, Giovanni, additional, Verderio, Paolo, additional, and Cortinovis, Umberto, additional

Published
2023
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13. Alterations in Plasma Lipid Profiles Associated with Melanoma and Therapy Resistance.

Author

Dei Cas, Michele, Ciniselli, Chiara Maura, Vergani, Elisabetta, Ciusani, Emilio, Aloisi, Mariachiara, Duroni, Valeria, Verderio, Paolo, Ghidoni, Riccardo, Paroni, Rita, Perego, Paola, Beretta, Giovanni Luca, Gatti, Laura, and Rodolfo, Monica

Subjects
*BLOOD lipids, *SATURATED fatty acids, *UNSATURATED fatty acids, *FATTY acid derivatives, *LIPID metabolism, *LIPIDS
Abstract

Dysfunctions of lipid metabolism are associated with tumor progression and treatment resistance of cutaneous melanoma. BRAF/MEK inhibitor resistance is linked to alterations of melanoma lipid pathways. We evaluated whether a specific lipid pattern characterizes plasma from melanoma patients and their response to therapy. Plasma samples from patients and controls were analyzed for FASN and DHCR24 levels and lipidomic profiles. FASN and DHCR24 expression resulted in association with disease condition and related to plasma cholesterol and triglycerides in patients at different disease stages (n = 144) as compared to controls (n = 115). Untargeted lipidomics in plasma (n = 40) from advanced disease patients and controls revealed altered levels of different lipids, including fatty acid derivatives and sphingolipids. Targeted lipidomics identified higher levels of dihydroceramides, ceramides, sphingomyelins, ganglioside GM3, sphingosine, sphingosine-1-phosphate, and dihydrosphingosine, saturated and unsaturated fatty acids. When melanoma patients were stratified based on a long/short-term clinical response to kinase inhibitors, differences in plasma levels were shown for saturated fatty acids (FA 16:0, FA18:0) and oleic acid (FA18:1). Our results associated altered levels of selected lipid species in plasma of melanoma patients with a more favorable prognosis. Although obtained in a small cohort, these results pave the way to lipidomic profiling for melanoma patient stratification. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Abstract 5506: Circulating immature neutrophils early detect hyperprogressive disease upon first-line PD-1/PD-L1 inhibitors in non-small cell lung cancer patients selecting best candidates for platinum-based chemotherapy and PD-1/PD-L1 inhibitors combinations

Author

Ferrara, Roberto, primary, Russo, Giuseppe Lo, additional, Ciniselli, Chiara Maura, additional, Piva, Annamaria, additional, Bassani, Barbara, additional, Jachetti, Elena, additional, Calareso, Giuseppina, additional, Duroni, Valeria, additional, Gregorio, Settimio Di, additional, Proto, Claudia, additional, Prelaj, Arsela, additional, De Toma, Alessandro, additional, Occhipinti, Mario, additional, Brambilla, Marta, additional, Manglaviti, Sara, additional, Mazzeo, Laura, additional, Rinaldi, Arturo, additional, Beninato, Teresa, additional, Ganzinelli, Monica, additional, De Braud, Filippo, additional, Garassino, Marina Chiara, additional, Verderio, Paolo, additional, Colombo, Mario Paolo, additional, and Sangaletti, Sabina, additional

Published
2023
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15. Supplementary Figure 1 from Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study

Author

Belfiore, Antonino, primary, Ciniselli, Chiara Maura, primary, Signoroni, Stefano, primary, Gariboldi, Manuela, primary, Mancini, Andrea, primary, Rivoltini, Licia, primary, Morelli, Daniele, primary, Masci, Enzo, primary, Bruno, Eleonora, primary, Macciotta, Alessandra, primary, Ricci, Maria Teresa, primary, Daveri, Elena, primary, Cattaneo, Laura, primary, Gargano, Giuliana, primary, Apolone, Giovanni, primary, Milione, Massimo, primary, Verderio, Paolo, primary, Pasanisi, Patrizia, primary, and Vitellaro, Marco, primary

Published
2023
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16. Data from Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study

Author

Belfiore, Antonino, primary, Ciniselli, Chiara Maura, primary, Signoroni, Stefano, primary, Gariboldi, Manuela, primary, Mancini, Andrea, primary, Rivoltini, Licia, primary, Morelli, Daniele, primary, Masci, Enzo, primary, Bruno, Eleonora, primary, Macciotta, Alessandra, primary, Ricci, Maria Teresa, primary, Daveri, Elena, primary, Cattaneo, Laura, primary, Gargano, Giuliana, primary, Apolone, Giovanni, primary, Milione, Massimo, primary, Verderio, Paolo, primary, Pasanisi, Patrizia, primary, and Vitellaro, Marco, primary

Published
2023
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17. Supplementary Legends from Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study

Author

Belfiore, Antonino, primary, Ciniselli, Chiara Maura, primary, Signoroni, Stefano, primary, Gariboldi, Manuela, primary, Mancini, Andrea, primary, Rivoltini, Licia, primary, Morelli, Daniele, primary, Masci, Enzo, primary, Bruno, Eleonora, primary, Macciotta, Alessandra, primary, Ricci, Maria Teresa, primary, Daveri, Elena, primary, Cattaneo, Laura, primary, Gargano, Giuliana, primary, Apolone, Giovanni, primary, Milione, Massimo, primary, Verderio, Paolo, primary, Pasanisi, Patrizia, primary, and Vitellaro, Marco, primary

Published
2023
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18. Supplementary Figure 2 from Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study

Author

Belfiore, Antonino, primary, Ciniselli, Chiara Maura, primary, Signoroni, Stefano, primary, Gariboldi, Manuela, primary, Mancini, Andrea, primary, Rivoltini, Licia, primary, Morelli, Daniele, primary, Masci, Enzo, primary, Bruno, Eleonora, primary, Macciotta, Alessandra, primary, Ricci, Maria Teresa, primary, Daveri, Elena, primary, Cattaneo, Laura, primary, Gargano, Giuliana, primary, Apolone, Giovanni, primary, Milione, Massimo, primary, Verderio, Paolo, primary, Pasanisi, Patrizia, primary, and Vitellaro, Marco, primary

Published
2023
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19. Supplementary Table 1 from Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study

Author

Belfiore, Antonino, primary, Ciniselli, Chiara Maura, primary, Signoroni, Stefano, primary, Gariboldi, Manuela, primary, Mancini, Andrea, primary, Rivoltini, Licia, primary, Morelli, Daniele, primary, Masci, Enzo, primary, Bruno, Eleonora, primary, Macciotta, Alessandra, primary, Ricci, Maria Teresa, primary, Daveri, Elena, primary, Cattaneo, Laura, primary, Gargano, Giuliana, primary, Apolone, Giovanni, primary, Milione, Massimo, primary, Verderio, Paolo, primary, Pasanisi, Patrizia, primary, and Vitellaro, Marco, primary

Published
2023
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20. Supplementary Figure 2 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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21. Supplementary Figure 5 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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22. Supplementary Table 3 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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23. Supplementary Figure 4 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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24. Supplementary Figure 1 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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25. Supplementary Table 1 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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26. Supplementary Table 2 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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27. Supplementary Figure 3 from Integrated Molecular and Immune Phenotype of HER2-Positive Breast Cancer and Response to Neoadjuvant Therapy: A NeoALTTO Exploratory Analysis

Author

Pizzamiglio, Sara, primary, Ciniselli, Chiara Maura, primary, Triulzi, Tiziana, primary, Gargiuli, Chiara, primary, De Cecco, Loris, primary, de Azambuja, Evandro, primary, Fumagalli, Debora, primary, Sotiriou, Christos, primary, Harbeck, Nadia, primary, Izquierdo, Miguel, primary, Nuciforo, Paolo, primary, Huober, Jens, primary, Cappelletti, Vera, primary, Cinieri, Saverio, primary, Piccart, Martine, primary, Daidone, Maria Grazia, primary, Pruneri, Giancarlo, primary, Colombo, Mario Paolo, primary, Tagliabue, Elda, primary, Verderio, Paolo, primary, and Di Cosimo, Serena, primary

Published
2023
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31. Periprosthetic effusions surrounding breast expander: a flow cytometric, immunohistochemical and molecular characterization

Author

Sala, Laura, Ciniselli, Chiara Maura, Bozzi, Fabio, Summo, Valeria, Bonini, Chiara, Brich, Silvia, Bertolotti, Alessia, Trupia, Desiré Viola, Volpi, Chiara Costanza, Pizzamiglio, Sara, Paolini, Biagio, Aiello, Antonella, Apolone, Giovanni, Verderio, Paolo, and Cortinovis, Umberto

Abstract

Introduction The synthesis of the periprosthetic capsule during implant-based breast reconstruction is the result of a coordinate cascade of inflammatory events ending in a fibrous tissue deposition around the expander or implant. Although the development of small volumes of fluid is one of the complications of prosthetic-based breast reconstruction, the characterization of the periprosthetic effusions coupled with the micro-textured devices, that have been recently introduced after the recall of macro-textured ones, is still lacking. The investigation of these periprosthetic effusions and paired capsules in terms of immunological content were the primary and secondary aims of the present study, respectively.Methods For this, 68 women, 41 of whom had periprosthetic effusions at the time of expander replacement with implant, were recruited. For each case, capsule and healthy dermal tissues were taken and for women with periprosthetic effusion, peripheral blood was also collected. Periprosthetic effusions and peripheral blood were characterized by cytometry while capsules and dermal tissues by immunohistochemistry and Nanostring analysis.Results The results showed an increase of Th1, Th2 lymphocytes and a HLA-DR+brightCD16+ cells (likely representing monocytes-derived macrophages) in periprosthetic effusions in respect to peripheral blood. These pro-inflammatory cells were counterbalanced by the gain of suppressive CD4 Treg cells. In the corresponding capsules, immunohistochemistry revealed the absence of Th1 cells and the presence of tissutal FOXP3 Treg. No significant difference in expression of inflammatory-related genes between capsules and dermal tissues was present.Conclusions These results suggest the presence of a Treg-controlled inflammation in both periprosthetic effusions and capsules.

Published
2024
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32. In a cohort of breast cancer screened patients the proportion of HER2 positive cases is lower than that earlier reported and pathological characteristics differ between HER2 3+ and HER2 2+/Her2 amplified cases

Author

Giuliani, Silvia, Ciniselli, Chiara Maura, Leonardi, Elena, Polla, Enzo, Decarli, Nicola, Luchini, Claudio, Cantaloni, Chiara, Gasperetti, Fabio, Cazzolli, Daniela, Berlanda, Gabriella, Bernardi, Daniela, Pellegrini, Marco, Triolo, Renza, Ferro, Antonella, Verderio, Paolo, and Barbareschi, Mattia

Published
2016
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35. Predictive Role of CD36 Expression in HER2-Positive Breast Cancer Patients Receiving Neoadjuvant Trastuzumab

Author

Ligorio, Francesca, primary, Di Cosimo, Serena, additional, Verderio, Paolo, additional, Ciniselli, Chiara Maura, additional, Pizzamiglio, Sara, additional, Castagnoli, Lorenzo, additional, Dugo, Matteo, additional, Galbardi, Barbara, additional, Salgado, Roberto, additional, Loi, Sherene, additional, Michiels, Stefan, additional, Triulzi, Tiziana, additional, Tagliabue, Elda, additional, El-Abed, Sarra, additional, Izquierdo, Miguel, additional, de Azambuja, Evandro, additional, Nuciforo, Paolo, additional, Huober, Jens, additional, Moscetti, Luca, additional, Janni, Wolfgang, additional, Coccia-Portugal, Maria Antonia, additional, Corsetto, Paola Antonia, additional, Belfiore, Antonino, additional, Lorenzini, Daniele, additional, Daidone, Maria Grazia, additional, Vingiani, Andrea, additional, Gianni, Luca, additional, Pupa, Serenella Maria, additional, Bianchini, Giampaolo, additional, Pruneri, Giancarlo, additional, and Vernieri, Claudio, additional

Published
2022
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36. Reply to Serrano et al. Comment on “Colletti et al. Prevalence and Management of Cancer of the Rectal Stump after Total Colectomy and Rectal Sparing in Patients with Familial Polyposis: Results from a Registry-Based Study. Cancers 2022, 14, 298”

Author

Colletti, Gaia, primary, Ciniselli, Chiara Maura, additional, Rausa, Emanuele, additional, Signoroni, Stefano, additional, Cocco, Ivana Maria Francesca, additional, Magarotto, Andrea, additional, Ricci, Maria Teresa, additional, Brignola, Clorinda, additional, Mancini, Andrea, additional, Cavalcoli, Federica, additional, Cattaneo, Laura, additional, Milione, Massimo, additional, Verderio, Paolo, additional, and Vitellaro, Marco, additional

Published
2022
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37. Predictive Role of CD36 Expression in HER2-Positive Breast Cancer Patients Receiving Neoadjuvant Trastuzumab

Author

Ligorio, Francesca, Di Cosimo, Serena, Verderio, Paolo, Ciniselli, Chiara Maura, Pizzamiglio, Sara, Castagnoli, Lorenzo, Dugo, Matteo, Galbardi, Barbara, Salgado, Roberto, Loi, Sherene, Michiels, Stefan, Triulzi, Tiziana, Tagliabue, Elda, El-abed, Sarra, Izquierdo, Miguel, de Azambuja, Evandro, Nuciforo, Paolo Giovanni, Huober, J., Moscetti, Luca, Janni, Wolfgang, Coccia-Portugal, Maria Antonia, Corsetto, Paola Antonia, Belfiore, Antonino, Lorenzini, Daniele, Daidone, Maria Grazia, Vingiani, Andrea, Gianni, Luca, Pupa, Serenella Maria, Bianchini, Giampaolo, Pruneri, Giancarlo, Vernieri, Claudio, Ligorio, Francesca, Di Cosimo, Serena, Verderio, Paolo, Ciniselli, Chiara Maura, Pizzamiglio, Sara, Castagnoli, Lorenzo, Dugo, Matteo, Galbardi, Barbara, Salgado, Roberto, Loi, Sherene, Michiels, Stefan, Triulzi, Tiziana, Tagliabue, Elda, El-abed, Sarra, Izquierdo, Miguel, de Azambuja, Evandro, Nuciforo, Paolo Giovanni, Huober, J., Moscetti, Luca, Janni, Wolfgang, Coccia-Portugal, Maria Antonia, Corsetto, Paola Antonia, Belfiore, Antonino, Lorenzini, Daniele, Daidone, Maria Grazia, Vingiani, Andrea, Gianni, Luca, Pupa, Serenella Maria, Bianchini, Giampaolo, Pruneri, Giancarlo, and Vernieri, Claudio

Abstract

Background: Despite huge efforts to identify biomarkers associated with long-term clinical outcomes in patients with early-stage HER2-positive breast cancer (HER2+ BC) treated with (neo)adjuvant anti-HER2 therapy, no reliable predictors have been identified so far. Fatty acid uptake, a process mediated by the transmembrane transporter CD36, has recently emerged as a potential determinant of resistance to anti-HER2 treatments in preclinical HER2+ BC models. Methods: Here, we investigated the association between baseline intratumor CD36 gene expression and event-free survival in 180 patients enrolled in the phase III trial Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimization (NeoALTTO), which randomly assigned stage II-III HER2+ BC patients to receive neoadjuvant lapatinib, trastuzumab, or lapatinib-trastuzumab in combination with chemotherapy. To this aim, we selected NeoALTTO trial patients for whom pretreatment whole transcriptomic data were available. The main study results were validated in an independent cohort of patients enrolled in the neoadjuvant phase II trial NeoSphere. Results: In 180 NeoALTTO patients, high intratumor CD36 expression was independently associated with worse event-free survival in patients treated with trastuzumab-based therapy (hazard ratio [HR] = 1.72, 95% confidence interval [CI] = 1.20 to 2.46), but not with lapatinib-based (HR = 1.02, 95% CI = 0.68 to 1.53) or trastuzumab-lapatinib-based (HR = 1.08, 95% CI = 0.60 to 1.94) therapy. Among 331 NeoSphere patients evaluated, high CD36 expression was independently associated with worse patient disease-free survival in both the whole study cohort (HR = 1.197, 95% CI = 1.002 to 1.428) and patients receiving trastuzumab-based neoadjuvant therapy (HR = 1.282, 95% CI = 1.049 to 1.568). Conclusions: High CD36 expression predicts worse clinical outcomes in early-stage HER2+ BC treated with trastuzumab-based neoadjuvant therapy., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2022

39. Additional file 1 of Gene signatures of circulating breast cancer cell models are a source of novel molecular determinants of metastasis and improve circulating tumor cell detection in patients

Author

Fina, Emanuela, Cleris, Loredana, Dugo, Matteo, Lecchi, Mara, Ciniselli, Chiara Maura, Lecis, Daniele, Bianchi, Giulia Valeria, Verderio, Paolo, Daidone, Maria Grazia, and Cappelletti, Vera

Subjects
Data_FILES
Abstract

Additional file 1: Supplementary information. File includes extended Methods section, 5 Figures and 6 Tables.

Published
2022
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40. sj-docx-3-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-3-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
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41. sj-docx-4-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-4-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
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42. sj-docx-6-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-6-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
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43. sj-docx-7-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-7-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
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44. sj-docx-2-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-2-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
View/download PDF

45. sj-docx-1-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fucà, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
View/download PDF

46. sj-docx-5-tam-10.1177_17588359221108687 – Supplemental material for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, Lecchi, Mara, Ciniselli, Chiara Maura, Ottini, Arianna, Spagnoletti, Andrea, Mazzeo, Laura, Morelli, Daniele, Frati, Paola, Stroscia, Martina, Ebrahem, Elisabella, Sottotetti, Elisa, Galli, Giulia, D’Elia, Maria Grazia, Lobefaro, Riccardo, Ducceschi, Monika, Di Guardo, Lorenza, Bhoori, Sherrie, Provenzano, Salvatore, Platania, Marco, Niger, Monica, Colombo, Elena, Nichetti, Federico, Duca, Matteo, Rivoltini, Licia, Mortarini, Roberta, Baili, Paolo, Apolone, Giovanni, de Braud, Filippo, Verderio, Paolo, and Damian, Silvia

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-5-tam-10.1177_17588359221108687 for Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center by Giovanni Fuc’, Mara Lecchi, Chiara Maura Ciniselli, Arianna Ottini, Andrea Spagnoletti, Laura Mazzeo, Daniele Morelli, Paola Frati, Martina Stroscia, Elisabella Ebrahem, Elisa Sottotetti, Giulia Galli, Maria Grazia D’Elia, Riccardo Lobefaro, Monika Ducceschi, Lorenza Di Guardo, Sherrie Bhoori, Salvatore Provenzano, Marco Platania, Monica Niger, Elena Colombo, Federico Nichetti, Matteo Duca, Licia Rivoltini, Roberta Mortarini, Paolo Baili, Giovanni Apolone, Filippo de Braud, Paolo Verderio and Silvia Damian in Therapeutic Advances in Medical Oncology

Published
2022
Full Text
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47. Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial

Author

Gündisch, Sibylle, Slotta-Huspenina, Julia, Verderio, Paolo, Ciniselli, Chiara Maura, Pizzamiglio, Sara, Schott, Christina, Drecoll, Enken, Viertler, Christian, Zatloukal, Kurt, Kap, Marcel, Riegman, Peter, Esposito, Irene, Specht, Katja, Babaryka, Gregor, Asslaber, Martin, Bodó, Koppany, den Bakker, Michael, den Hollander, Jan, Fend, Falko, Neumann, Jens, Reu, Simone, Perren, Aurel, Langer, Rupert, Lugli, Alessandro, Becker, Ingrid, Richter, Thomas, Kayser, Gian, May, Annette M., Carneiro, Fatima, Lopes, José Manuel, Sobin, Leslie, Höfler, Heinz, and Becker, Karl-Friedrich

Published
2014
Full Text
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48. Abstract P2-13-12: High CD36 expression predicts worse event free survival in HER2-positive breast cancer patients treated with neoadjuvant trastuzumab-based therapy: An exploratory analysis of the NeoALTTO study

Author

Ligorio, Francesca, primary, Cosimo, Serena Di, additional, Verderio, Paolo, additional, Ciniselli, Chiara Maura, additional, Pizzamiglio, Sara, additional, Castagnoli, Lorenzo, additional, Triulzi, Tiziana, additional, Tagliabue, Elda, additional, El-Abed, Sarra, additional, Izquierdo, Miguel, additional, de Azambuja, Evandro, additional, Nuciforo, Paolo, additional, Huober, Jens, additional, Moscetti, Luca, additional, Janni, Wolfgang, additional, Coccia-Portugal, M, additional, Corsetto, Paola, additional, Belfiore, Antonino, additional, Lorenzini, Daniele, additional, Daidone, Maria Grazia, additional, VIngiani, Andrea, additional, Pupa, Serenella M, additional, Pruneri, Giancarlo, additional, and Vernieri, Claudio, additional

Published
2022
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49. Prevalence and Management of Cancer of the Rectal Stump after Total Colectomy and Rectal Sparing in Patients with Familial Polyposis: Results from a Registry-Based Study

Author

Colletti, Gaia, primary, Ciniselli, Chiara Maura, additional, Signoroni, Stefano, additional, Cocco, Ivana Maria Francesca, additional, Magarotto, Andrea, additional, Ricci, Maria Teresa, additional, Brignola, Clorinda, additional, Bagatin, Clara, additional, Cattaneo, Laura, additional, Mancini, Andrea, additional, Cavalcoli, Federica, additional, Milione, Massimo, additional, Verderio, Paolo, additional, and Vitellaro, Marco, additional

Published
2022
Full Text
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50. Efficacy of mRNA anti-SARS-CoV-2 vaccination and dynamics of humoral immune response in patients with solid tumors: results from the institutional registry of an Italian tertiary cancer center

Author

Fucà, Giovanni, primary, Lecchi, Mara, additional, Ciniselli, Chiara Maura, additional, Ottini, Arianna, additional, Spagnoletti, Andrea, additional, Mazzeo, Laura, additional, Morelli, Daniele, additional, Frati, Paola, additional, Stroscia, Martina, additional, Ebrahem, Elisabella, additional, Sottotetti, Elisa, additional, Galli, Giulia, additional, D’Elia, Maria Grazia, additional, Lobefaro, Riccardo, additional, Ducceschi, Monika, additional, Di Guardo, Lorenza, additional, Bhoori, Sherrie, additional, Provenzano, Salvatore, additional, Platania, Marco, additional, Niger, Monica, additional, Colombo, Elena, additional, Nichetti, Federico, additional, Duca, Matteo, additional, Rivoltini, Licia, additional, Mortarini, Roberta, additional, Baili, Paolo, additional, Apolone, Giovanni, additional, de Braud, Filippo, additional, Verderio, Paolo, additional, and Damian, Silvia, additional

Published
2022
Full Text
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