159 results on '"Cignarella, Giorgio"'
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2. Antinociceptive action of DBO 17 and DBO 11 in mice: two 3,8 diazabicyclo (3.2.1.) octane derivates with selective μ opioid receptor affinity
3. Computer-aided structure-affinity relationships in a set of piperazine and 3,8-diazabicyclo[3.2.1]octane derivatives binding to the μ-opioid receptor
4. Selective γ-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of γ-hydroxybutyric acid
5. Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3′ allyl end and at the phenyl ring of the cinnamyl chain on μ-receptor affinity and opioid antinociception
6. N-3(9)-Arylpropenyl- N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes as μ-Opioid receptor agonists. Effects on μ-Affinity of arylalkenyl chain modifications
7. Stereoselectivity of NCS-382 binding to γ-hydroxybutyrate receptor in the rat brain
8. Central effects of 1,4-butanediol are mediated by GABA B receptors via its conversion into γ-hydroxybutyric acid
9. 3,8-Diazabicyclo-[3.2.1]-octane derivatives as analogues of ambasilide, a Class III antiarrhythmic agent
10. Role of GABA B receptors in the sedative/hypnotic effect of γ-hydroxybutyric acid
11. The opioid-receptor-like 1 (ORL-1) as a potential target for new analgesics
12. I 3,6-diazabiciclo[3.1.1]eptani: una nuova serie di potenti agonisti per i recettori µ degli oppioidi
13. ChemInform Abstract: Pyridazinones and Their Tricyclic Congeners: Chemistry and Biology
14. ChemInform Abstract: Novel Adrenoceptor Antagonists with a Tricyclic Pyrrolodipyridazine Skeleton.
15. ChemInform Abstract: Behavior of 5,6-Dihydrobenzo[h]cinnolinones Towards Hydrazine. Synthesis of Benzo[h]cinnolinones and of 4-Aminobenzo[h]cinnolinones.
16. ChemInform Abstract: The Opioid-Receptor-Like 1 (ORL-1) as a Potential Target for New Analgesics
17. ChemInform Abstract: Preparation of Thieno[3,2-h]cinnolinones as Matrix Metalloproteinase Inhibitors.
18. ChemInform Abstract: Synthesis and Cytotoxic Activities of Pyrrole[2,3-d]pyridazin-4-one Derivatives.
19. Synthesis, Modelling, and Antimitotic Properties of Tricyclic Systems Characterised by a 2-(5-Phenyl-1H-pyrrol-3-yl)-1,3,4-oxadiazole Moiety
20. Synthesis, Screening, and Molecular Modeling of New Potent and Selective Antagonists at the α1d Adrenergic Receptor
21. Congo red analogues as potential anti-prion agents
22. 6-Chloropyridazin-3-yl Derivatives Active as Nicotinic Agents: Synthesis, Binding, and Modeling Studies
23. Central effects of 1,4-butanediol are mediated by GABAB receptors via its conversion into γ-hydroxybutyric acid
24. ChemInform Abstract: 3,8‐Diazabicyclo‐[3.2.1]‐octane Derivatives as Analogues of Ambasilide, a Class III Antiarrhythmic Agent.
25. Synthesis and Cytotoxic Activities of Pyrrole[2,3-d]pyridazin-4-one Derivatives.
26. Role of GABAB receptors in the sedative/hypnotic effect of γ-hydroxybutyric acid
27. Phenylpiperazinylalkylamino Substituted Pyridazinones as Potent α1 Adrenoceptor Antagonists
28. ChemInform Abstract: Synthesis and Aldose Reductase Inhibitory Activity of a New Series of Benzo[h]cinnolinone Derivatives.
29. Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives
30. Synthesis, Molecular Modeling, and Opioid Receptor Affinity of 9,10-Diazatricyclo[4.2.1.12,5]decanes and 2,7-Diazatricyclo[4.4.0.03,8]decanes Structurally Related to 3,8-Diazabicyclo[3.2.1]octanes
31. ChemInform Abstract: Behavior of 5,6‐Dihydrothieno[2,3‐h]cinnolin‐3(2H)‐one and 5,6‐Dihydrothieno[3,2‐h]cinnolin‐3(2H)‐one Towards Hydrazine. Synthesis of Thienocinnolinones and of 4‐Aminothienocinnolinones.
32. Preparation of Thieno[3,2-h]cinnolinones as Matrix Metalloproteinase Inhibitors
33. Structural and Conformational Studies of 3,8-Diazabicyclo[3.2.1]octane Derivatives, Selective Agonists of m-Opioid Receptors
34. Behaviour of 5,6‐dihydrothieno[2,3‐h]cinnolin‐3(2H)‐one and 5,6‐dihydrothieno[3,2‐h]cinnolin‐3(2H)‐one towards hydrazine. Synthesis of thienocinnolinones and of 4‐aminothienocinnolinones
35. ChemInform Abstract: Diabetes Complications and Their Potential Prevention: Aldose Reductase Inhibition and Other Approaches
36. Behavior of 5,6‐dihydrobenzo[h]cinnolinones towards hydrazine. Synthesis of benzo[h]cinnolinones and of 4‐Aminobenzo[h]cinnolinones
37. Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches
38. Novel Adrenoceptor Antagonists with a Tricyclic Pyrrolodipyridazine Skeleton
39. Pyridazinones and their tricyclic congeners: Chemistry and biology
40. Mono- and Disubstituted-3,8-diazabicyclo[3.2.1]octane Derivatives as Analgesics Structurally Related to Epibatidine: Synthesis, Activity, and Modeling
41. Development of pharmacophores for inhibitors of the rapid component of the cardiac delayed rectifier potassium current
42. Development of pharmacophores for inhibitors of the rapid component of the cardiac delayed rectifier potassium current
43. New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications
44. 2,2,6- and 2,3,5-Trimethylpiperazines as monocyclic analogues of the μ-opioid agonist 3,8-diazabicyclo[3.2.1]octanes: Synthesis, modeling, and activity
45. Tricyclic indenopyridazine derivatives: Synthesis, cytotoxic activity and DNA‐binding properties
46. Synthesis, Activity, and Molecular Modeling of a New Series of Tricyclic Pyridazinones as Selective Aldose Reductase Inhibitors
47. Unexpected behaviour of the oxidizing agent sodiumm-nitrobenzenesulfonate: Synthesis of a new class of 5-hydroxy benzopyrano-[4,3-c]pyridazin-3(2H)-ones
48. Computer-aided structure-affinity relationships in a set of piperazine and 3,8-diazabicyclo[3.2.1]octane derivatives binding to the ?-opioid receptor
49. Synthesis of a new series of 8-substituted-2,8-diazaspiro[4.5]decan-3-ones
50. Synthesis of a new series ofN-substituted-3-[l-alkyl(aryl)- 4-piperidyl]azetidin-2-ones as possible muscarinic agents
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