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Abstract Preeclampsia is a pregnancy disorder that seriously affects the outcome of mothers and infants and lacks effective prediction and diagnosis methods. ELABELA is the second endogenous ligand of the apelin receptor (APJ) and is associated with the pathogenesis of preeclampsia. In a previous study, the authors found that the downregulation of ELABELA expression is closely related to late‐onset preeclampsia, which may be a marker for the clinical diagnosis of late‐onset preeclampsia. In this study, the authors again collected 120 maternal blood samples, including 60 pregnant women with a medical diagnosis of late‐onset preeclampsia. ELISA results showed that the serum ELABELA concentration in late‐onset preeclampsia pregnant women (12.57 ± 7.77 ng/mL) was significantly lower than that in normal pregnant women (36.99 ± 23.58 ng/mL), which was consistent with previously reported results. Therefore, the authors used an ELABELA monoclonal antibody to label four colloidal gold nanoparticles with different diameters (15, 30, 55, and 150 nm) and developed a transverse‐flow immunochromatographic band for the rapid and accurate detection of serum ELABELA levels. The strip test shows that colloidal gold with a diameter of 30 nm can be used as a good ELABELA detection marker and had more than 90% positive detection effect. Therefore, the authors hope that the colloidal gold strip with ELABELA as the diagnostic index developed by us will be popularized and applied in clinical diagnosis.

The three-dimensional (3D) reconstruction of buildings using photogrammetric point clouds is important for many applications, ranging from digital city construction to urban energy consumption analysis. However, problems such as building complexity and point cloud flaws may lead to incorrect modeling, which will affect subsequent steps such as texture mapping. This paper introduces a pipeline for building surface reconstruction from photogrammetric point clouds, employing a hybrid method that combines connection evaluation and framework optimization. Firstly, the plane segmentation method divides building point clouds into several pieces, which is complemented by a proposed candidate plane generation method aimed at removing redundancies and merging similarities. Secondly, the improved connection evaluation method detects potential skeleton lines from different planes. Subsequently, a framework optimization method is introduced to select suitable undirected polygonal boundaries from planes, forming the basis for plane primitives. Finally, by triangulating all plane primitives and filling holes, a building surface polygonal model is generated. Experiments conducted on various building examples provide both qualitative and quantitative evidence that the proposed hybrid method outperforms many existing methods, including traditional methods and deep learning methods. Notably, the proposed method successfully reconstructs the main building structures and intricate details, which can be further used to generate textural models and semantic models. Experimental results validate that the proposed method can be used for the surface reconstruction from photogrammetric point clouds of planar buildings.

Abstract We present a new 3‐D seismic structural model of the eastern Indonesian region and its surroundings from full‐waveform inversion (FWI) that exploits seismic data filtered at periods between 15–150 s. SASSY21—a recent 3‐D FWI tomographic model of Southeast Asia—is used as a starting model, and our study region is characterized by particularly good data coverage, which facilitates a more refined image. We use the spectral‐element solver Salvus to determine the full 3‐D wavefield, accounting for the fluid ocean explicitly by solving a coupled system of acoustic and elastic wave equations. This is computationally more expensive but allows seismic waves within the water layer to be simulated, which becomes important for periods ≤20 s. We investigate path‐dependent effects of surface elevation (topography and bathymetry) and the fluid ocean on synthetic waveforms, and compare our final model to the tomographic result obtained with the frequently used ocean loading approximation. Furthermore, we highlight some of the key features of our final model—SASSIER22—after 34 L‐BFGS iterations, which reveals detailed anomalies down to the mantle transition zone, including a convergent double‐subduction zone along the southern segment of the Philippine Trench, which was not evident in the starting model. A more detailed illumination of the slab beneath the North Sulawesi Trench reveals a pronounced positive wavespeed anomaly down to 200 km depth, consistent with the maximum depth of seismicity, and a more diffuse but aseismic positive wavespeed anomaly that continues to the 410 km discontinuity.

Unlike stable cratons elsewhere in the world, the lithosphere is strongly thinned in the east of both the North China Craton (NCC) and the Yangtze Craton (YZC) compared with the west. We deployed four active-source onshore-offshore wide-angle seismic survey lines in the eastern NCC and YZC from 2010 to 2016 with the aim of revealing the mechanism of lithospheric thinning and the process of the collision between the NCC and YZC. We obtained high-resolution crustal P-wave velocity models for the eastern NCC and YZC based on seismic forward modeling, travel-time tomography, and finite-difference wave-field modeling. Based on our integrated geophysical study and previous work, we propose a five-stage model for the collision between the YZC and NCC, with different dominant geodynamic mechanisms in each stage. Our collision model shows that lithospheric thinning in the eastern NCC and YZC is a consequence of the NCC-YZC collision and subduction of the Pacific plate.

Abstract The region around the Celebes Sea, SE Asia, is evolving within a convergent tectonic environment involving the Pacific plate to the east and the Indian‐Australian plate to the south. It is arguably one of the most tectonically complex regions in the world and serves as an ideal setting to study dynamic interactions between the Pacific and Tethys tectonic domains. The issue of which subducting plate plays a leading role in governing the regional mantle flow is not well understood. Mantle flow can be characterized by seismic anisotropy observations, providing clues for understanding regional tectonics. We conducted SKS‐wave splitting analysis by using data from seven seismic stations located around the Celebes Sea. Our results, when combined with previous observations, suggest the presence of various types of mantle flow in this area, including (a) corner flow in the mantle wedge above the westward‐subducting Molucca Sea (Sangihe) slab, (b) two‐layer anisotropy related to the eastward‐subducting Molucca Sea (Halmahera) slab, (c) deflected flow due to proximity to the Sangihe slab's edges, (d) trench‐normal mantle flow beneath southeastern Borneo due to the subduction of the Indian‐Australian plate, and (e) Northwest Borneo‐Palawan trough‐parallel mantle flow beneath northeastern Borneo. Various types of mantle flow indicate that the dynamic interactions of adjacent subduction zones played crucial roles in influencing the regional upper mantle dynamics between the Tethys and western Pacific domains since the breakup of the Gondwana supercontinent in the Mesozoic.